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Targets Recommended: GPR84

Results for "6833-84-7" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-N6790

    Ammonium ionophore I

    Potassium Channel Mitochondrial Metabolism Apoptosis Cancer Infection
    Nonactin is a naturally occurring macrotetrolide antibiotic from Streptomyces griseus. Nonactin acts as an ionophore for monovalent cations, including K +, and NH4 +. Nonactin is able to uncouple the oxidative phosphorylation of mitochondria. Nonactin selectively induces apoptosis in cell lines harboring active mutant β-catenin. Nonactin inhibits the surface expression of endogenous HSP60.