Search Result
Results for "
7-(4-Bromobutoxy)-3,4-dihydro-2(1H)-quinolinone-d8
" in MedChemExpress (MCE) Product Catalog:
5
Biochemical Assay Reagents
17
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W010130
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3,4-dihydro-7-hydroxy-2(1H)-quinolinone
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Monoamine Oxidase
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Neurological Disease
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7-Hydroxy-3,4-dihydro-2(1H)-quinolinone (3,4-Dihydro-7-hydroxy-2(1H)-quinolinone) is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B .
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- HY-N1637
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Bacterial
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Infection
Cancer
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1-Methyl-2-pentyl-4(1H)-quinolinone, a quinolone alkaloid isolated from the fruits of Evodia Rutaecarpa, possesses antibacterial and cytotoxic activities for cancer cells .
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- HY-135021
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5-HT Receptor
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Others
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3,4-Dihydro Naratriptan is a serotonin 5-HT1-receptor agonist. 3,4-Dihydro Naratriptan exhibits selective vasoconstrictor activity. 3,4-Dihydro Naratriptan can be used for migraine diseases research .
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- HY-131252
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dihydro E2020
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Cholinesterase (ChE)
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Neurological Disease
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Dihydro Donepezil (Dihydro E2020) is a metabolite of Donepezil. Donepezil is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bAChE and hAChE, respectively .
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- HY-N10456
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Bacterial
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Infection
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1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone is a potent antibacterial agent with an MIC50 value of 22 µM and an MIC90 value of 50 µM for Helicobacter pyloriStrain 51. 1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone has the potential for the research of gastric and duodenal ulcers .
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- HY-N10497
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nAChR
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Neurological Disease
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Dihydro-β-erythroidine is a a competitive nicotinic receptor antagonist. Dihydro-β-erythroidine blocks the discriminative stimulus properties of nicotine. Dihydro-β-erythroidine inhibits the anxiolytic effect of nicotine induced .
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- HY-114862
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13,14-dihydro-15(R)-PGE1
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Endogenous Metabolite
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Others
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13,14-dihydro-15(R)-Prostaglandin E1 (13,14-dihydro-15(R)- PGE1) is an analog of 13,14-dihydro- PGE1 which has the hydroxyl group at C-15 in the unnatural R configuration .
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- HY-142180S
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- HY-146770S
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- HY-146775S
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-
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- HY-N10350
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Others
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Cancer
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2,3-Dihydro-3-methoxywithaferin A is an analogue of 2,3-dihydrowithaferin-A. 2,3-Dihydro-3-methoxywithaferin A inhibits proiiferation of P388 cells[1].
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- HY-144235S
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-
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- HY-N9301
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Others
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Others
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11,12-Dihydro-7-hydroxyhedychenone (compound 11) is a natural compound .
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- HY-118830
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DK-PGD2; 15-Oxo-13,14-dihydro-PGD2; 13,14-dihydro-15-keto-PGD2
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Prostaglandin Receptor
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Endocrinology
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13, 14-Dihydro-15-keto prostaglandin D2 (DK-PGD2) is a PGD2 metabolite formed by the 15-hydroxyl PGDH pathway. 13, 14-Dihydro-15-keto prostaglandin D2 is a selective agonist for the DP2 receptor. 13, 14-Dihydro-15-keto prostaglandin D2 can inhibit ion flux in canine colonic mucosa preparation .
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- HY-N10748
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Others
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Cancer
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2',3'-Dihydro-2'-hydroxyprotoapigenone is a natural protoflavonoid found in ferns impair .
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- HY-N6787
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dihydrothymine
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Endogenous Metabolite
|
Metabolic Disease
|
5,6-Dihydro-5-methyluracil (Dihydrothymine), an intermediate breakdown product of thymine, comes from animal or plants. 5,6-Dihydro-5-methyluracil (Dihydrothymine) can be toxic when present at abnormally high levels .
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- HY-N10091
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Apoptosis
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Others
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2,3-Dihydro-3α-methoxynimbolide is a limonoid compound isolated from the extracts of bark, leaves, roots, and seeds of Azadirachta indica A. Juss. var. siamensis Valeton. 2,3-Dihydro-3α-methoxynimbolide exhibits potent cyto-toxicities against one or more cell lines. 2,3-Dihydro-3α-methoxynimbolide activates caspases-3, -8, and -9, while increases the ratio of Bax/Bcl-2. 2,3-Dihydro-3α-methoxynimbolide induces apoptosis via both mitochondrial and death receptor pathways in AZ521 .
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- HY-106689
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- HY-106689A
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-
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- HY-N10907
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Bacterial
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Infection
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4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl- (compound 2) is a quinolone alkaloid that can be isolated from Cnidium. 4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl- has methicillin-resistant Staphylococcus aureus (MRSA) activity, with MIC values of 32 μg/mL (ATCC 33591) and 16 μM/mL (ATCC 25923), respectively .
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- HY-118754
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- HY-N9088
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-
-
- HY-135385
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-
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- HY-137591
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Others
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Endocrinology
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13,14-Dihydro-15-keto-PGE1 is an inactive metabolite of PGE1. 13, 14-Dihydro-15-Keto-pGE1 inhibited platelet aggregation in ADP-induced human isolated platelet-rich plasma with IC50 14.8 μg/mL .
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-
- HY-113254S1
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-
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- HY-113254S
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-
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- HY-147178
-
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Others
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Others
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C-6 NBD-dihydro-Ceramide is a membrane-permeable ceramides. C-6 NBD-dihydro-Ceramide is a biologically active fluorescent analog of short chain .
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-
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- HY-113461
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Others
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Others
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13,14-Dihydro-15-keto-prostaglandin A2 is a product of the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2. It is further broken down into bicyclo PGE2, which acts as a biomarker for PGE2 synthesis .
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- HY-N6787S
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dihydrothymine-d6
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Endogenous Metabolite
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Metabolic Disease
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5,6-Dihydro-5-methyluracil-d6 is the deuterium labeled 5,6-Dihydro-5-methyluracil. 5,6-Dihydro-5-methyluracil (Dihydrothymine), an intermediate breakdown product of thymine, comes from animal or plants. 5,6-Dihydro-5-methyluracil (Dihydrothymine) can be toxic when present at abnormally high levels[1].
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- HY-W319671S
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-
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- HY-130484
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Parasite
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2,3-Dehydro-3,4-dihydro ivermectin is an analog of ivermectin (HY-15310) and an anthelmintic. 2,3-Dehydro-3,4-dihydro ivermectin has activity against L. amazonensis promastigotes and amastigotes (IC50s=13.8 and 3.6 µM, respectively) without inducing cytotoxicity to macrophages (IC50= 65.5 µM).
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- HY-163373
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Others
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13,14-Dihydro-15-keto prostaglandin D1 is a derivative of prostaglandin D1 .
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- HY-N8888
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Others
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Others
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10,11-Dihydro-24-hydroxyaflavinine (10,23,24,25-tetrahydro-24-hydroxyaflavinine), an aflavinine analog, is a natural product that can be isolated from Ascostromata of Eupenicillium crustaceum .
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- HY-W008646
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- HY-116083
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Endogenous Metabolite
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Others
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13,14-Dihydro-15-keto-tetranor prostaglandin D2 (Compound VI) is a prostaglandin D2 metabolite. 13,14-Dihydro-15-keto-tetranor prostaglandin D2 as a biomarker can be used to study prostaglandin D2-related diseases .
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- HY-78667
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Biochemical Assay Reagents
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Others
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6,7-Dihydro-4-benzo[b]thiophenone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-N10676
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Others
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Cancer
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8,8a-Dihydro-8-hydroxygambogic acid is a natural product, that can be isolated from the resin of Garcinia hanburyi. 8,8a-Dihydro-8-hydroxygambogic acid shows anticancer activity .
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- HY-113208
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Endogenous Metabolite
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Others
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13,14-Dihydro-15-keto PGF2a is an endogenous metabolite present in Blood that can be used for the research of Pregnancy .
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- HY-W756041
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rel-(1S,2S)-dihydro bupropion-d9 hydrochloride
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Isotope-Labeled Compounds
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Others
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rel-(1S,2S)-Dihydro bupropion-d9 hydrochloride is the deuterium labeled rel-(1S,2S)-Dihydro bupropion hydrochloride.
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- HY-34692
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(3,4-Dihydro-2H-pyran-2-yl)methanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-152352
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Nucleoside Antimetabolite/Analog
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Cancer
|
7,8-Dihydro-8-oxo-7-propargyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-113208AS1
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-
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- HY-W867679S
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- HY-77434
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9-DHAB III; 13-Acetyl-9-dihydrobaccatin III
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Others
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Cancer
|
9-Dihydro-13-acetylbaccatin III (9-DHAB III) is an intermediate for taxol analog preparations.
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- HY-W745349
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-
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- HY-107670
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DHβE hydrobromide
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nAChR
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Neurological Disease
|
Dihydro-β-erythroidine (DHβE) hydrobromide is a potent, orally active, and competitive antagonist of neuronal nAChRs. Dihydro-β-erythroidine hydrobromide shows selectivity for α4β4 and α4β2 nAChRs, with IC50s of 0.19 and 0.37 μM, respectively. Antidepressant-like activities .
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- HY-113113
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13,14-dihydroprostaglandin E1
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Endogenous Metabolite
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Metabolic Disease
|
13,14-Dihydro PGE1 is a metabolite of PGE1 (Prostaglandin E1) which inhibits the ADP-induced platelet aggregation (ID50 = 10.8 ng/mL platelet rich plasma) .
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- HY-139968S
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Isotope-Labeled Compounds
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Others
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13,14-Dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 is the deuterium labeled 13,14-Dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1[1].
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- HY-34097
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5-Bromo-2,3-dihydro-1H-isoindol-1-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-114656
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dihydroprostaglandin F1α
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Others
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Endocrinology
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Dihydro-PGF1α is a potential metabolite of PGF1α .
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-
- HY-154284
-
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Nucleoside Antimetabolite/Analog
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Cancer
|
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-152347
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|
Nucleoside Antimetabolite/Analog
|
Cancer
|
1-Amino-3’-deoxy-7,8-dihydro-8-oxoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
- HY-N0975
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Others
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Metabolic Disease
|
1,11b-Dihydro-11b-hydroxymaackiain, a pterocarpane extract from the stems of Erycibe expansa, show a hepatoprotective effect .
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- HY-152338
-
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Nucleoside Antimetabolite/Analog
|
Cancer
|
7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-152385
-
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Nucleoside Antimetabolite/Analog
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Others
|
5,6-Dihydro-ara-uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152364
-
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Nucleoside Antimetabolite/Analog
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Cancer
|
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-152604
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Nucleoside Antimetabolite/Analog
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Others
|
3,4-Dihydro-3-oxo-4-β-D-ribofuranosyl-2-pyrazinecarboxamide is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
- HY-152824
-
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Nucleoside Antimetabolite/Analog
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Others
|
(R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152373
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Nucleoside Antimetabolite/Analog
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Cancer
|
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-N1772
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|
(3S,4S)-3,4-Dihydro-3,4-dihydroxynaphthalen-1(2H)-one (compound 9) is α-tetralone galloylglucoside that can be isolated from Juglans sigillata .
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- HY-152407
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Nucleoside Antimetabolite/Analog
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Others
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7-Allyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152431
-
|
Nucleoside Antimetabolite/Analog
|
Others
|
1-Amino-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
- HY-152436
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Nucleoside Antimetabolite/Analog
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Others
|
7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152328
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Nucleoside Antimetabolite/Analog
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Cancer
|
7-Ethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
- HY-152381
-
|
Nucleoside Antimetabolite/Analog
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Cancer
|
1,9-Dihydro-9-β-D-xylofuranosyl-6H-purin-6-one is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154283
-
|
Nucleoside Antimetabolite/Analog
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Cancer
|
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-152341
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Nucleoside Antimetabolite/Analog
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Cancer
|
7-(Butyn-2-yl)-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7-(Butyn-2-yl)-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-W053705
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-
- HY-N9303
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-
- HY-152491
-
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Nucleoside Antimetabolite/Analog
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Others
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7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
- HY-152333
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Nucleoside Antimetabolite/Analog
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Cancer
|
7-n-Butyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
- HY-152331
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|
Nucleoside Antimetabolite/Analog
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Cancer
|
7-n-Propyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-D1507
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Fluorescent Dye
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Others
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1-[3-(Succinimidyloxycarbonyl)benzyl]-4-[2-(3,4-dihydro-2H-1-benzopyran-6-yl)-5-oxazolyl]pyridinium bromide is a fluorescence dye .
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- HY-154425
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Nucleoside Antimetabolite/Analog
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Others
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2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-105000S1
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Isotope-Labeled Compounds
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Others
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trans-Dihydro Tetrabenazine-d7 is deuterium labeled (2S,3S,11bS)-3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol.
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- HY-152432
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Nucleoside Antimetabolite/Analog
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Others
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1-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
- HY-N4164
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Apoptosis
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Cancer
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Schinifoline, a 4-quinolinone derivative isolated from Zanthoxylum schinifolium Sieb, improves radiosensitizing effect, and effects cell cycle and apoptotic-inducing effects in cancer .
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-
- HY-N10885
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Others
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Others
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α,β-Dihydro-4,6-dihydroxy-2-methoxy-3-methylchalcone (compound 7) is a nature product that could be isolated from dragons blood of Daemonorops draco .
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-
- HY-N9300
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Others
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Inflammation/Immunology
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1,6-Dihydro-4,7-epoxy-1-methoxy-3,4-methylenedioxy-6-oxo-3,8-lignan, a lignan derivative from the ethyl acetate soluble fraction of twigs of Magnolia denudate (Magnoliaceae), exhibits anti-platelet-activating factor (PAF) activity. PAF is a potent lipid mediator in inflammation and asthma .
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- HY-W140284S
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Isotope-Labeled Compounds
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Others
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6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate-d8 (hydrochloride) is the deuterium labeled 6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate hydrochloride[1].
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- HY-152703
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Nucleoside Antimetabolite/Analog
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Others
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2-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(beta-D-xylo furanosyl)purine (G159-82) PTPD-2 Confidential is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
- HY-152405
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Nucleoside Antimetabolite/Analog
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Others
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6-Amino-1,2-dihydro-2-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
- HY-152616
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Nucleoside Antimetabolite/Analog
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Others
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2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
- HY-135794
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11-KDHT; 5α-dihydro-11-keto testosterone
|
Androgen Receptor
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Endocrinology
|
11-Ketodihydrotestosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a Ki of 20.4 nM and an EC50 of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells .
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-
- HY-146708S
-
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Isotope-Labeled Compounds
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Others
|
((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- 15N4 (sodium) is a 15N-labeled ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate (so
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- HY-N10639
-
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Others
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Others
|
(1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran is a sesquiterpene polyol ester. (1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran can be used for the research of various biochemical .
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-
- HY-W068697
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Vinylacetic acid
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Others
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Others
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3-Butenoic acid (Vinylacetic acid) can be used to synthesize bicyclic 3,6-dihydro-1,2-oxazine. Strained bicyclic 3,6-dihydro-1,2-oxazine is a reactive substrate in domino metathesis with an external alkene .
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-
- HY-N0976
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11b-Hydroxy-11b,1-dihydromedicarpin
|
Interleukin Related
|
Inflammation/Immunology
|
1,11b-Dihydro-11b-hydroxymedicarpin (11b-Hydroxy-11b,1-dihydromedicarpin) is a pterocarpan from Ononis viscosa subsp. breviflora is a Medicarpin derivative . Medicarpin, a natural pterocarpan, heals cortical bone defect by activation of Notch and Wnt canonical signaling pathways . Medicarpin prevents arthritis in post-menopausal conditions by arresting the expansion of TH17 cells and pro-inflammatory cytokines. Medicarpin down-regulates pro-inflammatory cytokines like TNF-α, IL-6 and IL-17A, while up-regulates anti-inflammatory cytokine IL-10 in arthritis (CIA) model of mice .
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-
- HY-135794S
-
11-KDHT-d3; 5α-dihydro-11-keto testosterone-d3
|
Androgen Receptor
|
Endocrinology
|
11-Ketodihydrotestosterone-d3 is the deuterium labeled 11-Ketodihydrotestosterone. 11-Ketodihydrotestosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a Ki of 20.4 nM and an EC50 of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells[1][2].
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- HY-116474
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Fungal
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Infection
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Viridicatol, a quinolinone alkaloid, is isolated from the fermentation of an endophytic fungus Penicillium sp. R22 in Nerium indicum. Viridicatol has strong antifungal activity against Staphylococcus aureus with MIC value of 15.6 μg/mL .
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- HY-118116
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bicyclo-PGEM; bicyclo-Prostaglandin E2
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Others
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Others
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bicyclo-PGE2 (bicyclo-PGEM) is a stable decomposition product of PGE2 and 13, 14-dihydro-15-ketone PGE2 .
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- HY-76487
-
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Biochemical Assay Reagents
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Others
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Dihydro-2H-pyran-4(3H)-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-W002623
-
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Biochemical Assay Reagents
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Others
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2,3-Dihydro-1,4-benzodioxine-6-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-W012991
-
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Biochemical Assay Reagents
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Others
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1,2-Dihydro-3H-1,2,4-triazole-3-thione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W002530
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Biochemical Assay Reagents
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Others
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(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-157925
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Bicyclo Prostaglandin E1
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Others
|
Others
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Bicyclo-PGE1 (Bicyclo Prostaglandin E1) is a stable, base-catalyzed transformation product of the PGE1 metabolite 13,14-dihydro-15-keto PGE1. Bicyclo-PGE1 can be used to estimate the biosynthesis and metabolism of PGE1 in vivo .
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-
- HY-N6619A
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-
- HY-N6619
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
Lycoramine hydrobromide, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine hydrobromide is a potent acetylcholinesterase (AChE) inhibitor .
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-
- HY-132994
-
|
Others
|
Others
|
TVD-0003510 is a carboxamide derivative, and involves in synthesis of (2-((6-(2-aminopyrimidine-5-carboxamido)-8-methoxy-3,4-dihydro-2H-pyrimido[1,2-c]quinazolin-9-yl)oxy)ethyl)piperazine-l-carboxylate (C51), as a part of tert-butyl2-(4-hydroxyphenyl)acetate .
|
-
- HY-149975
-
|
iGluR
|
Neurological Disease
|
AMPA receptor modulator-4, a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BTD), is an orally active positive allosteric modulator of the AMPA receptors (AMPAR PAMs). AMPA receptor modulator-4 can cross the blood-brain barrier. AMPA receptor modulator-4 increases the cognition performance and improves working memory performance in mice .
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Cat. No. |
Product Name |
Type |
-
- HY-78667
-
|
Biochemical Assay Reagents
|
6,7-Dihydro-4-benzo[b]thiophenone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-76487
-
|
Biochemical Assay Reagents
|
Dihydro-2H-pyran-4(3H)-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002623
-
|
Biochemical Assay Reagents
|
2,3-Dihydro-1,4-benzodioxine-6-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W012991
-
|
Biochemical Assay Reagents
|
1,2-Dihydro-3H-1,2,4-triazole-3-thione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002530
-
|
Biochemical Assay Reagents
|
(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No. |
Product Name |
Target |
Research Area |
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Compare |
Product Name |
Species |
Source |
Compare Products
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* This product has been "discontinued".
Optimized version of product available:
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Cat. No. |
Product Name |
Chemical Structure |
-
- HY-113254S1
-
|
13,14-Dihydro-15-keto-PGE2-d9 is the deuterium labeled 13,14-Dihydro-15-keto-PGE2[1].
|
-
-
- HY-142180S
-
|
cis (2,3)-Dihydro tetrabenazine-d6 is the deuterium labeled cis (2,3)-Dihydro tetrabenazine[1].
|
-
-
- HY-146770S
-
|
Dihydro FF-MAS-d6 is deuterium labeled Dihydro FF-MAS.
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-
-
- HY-146775S
-
|
Dihydro T-MAS-d6 is deuterium labeled Dihydro T-MAS.
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-
-
- HY-144235S
-
|
cis-Dihydro Tetrabenazine-d7 is the deuterium labeled cis-Dihydro Tetrabenazine[1].
|
-
-
- HY-113254S
-
|
13,14-Dihydro-15-keto-PGE2-d4 is the deuterium labeled 13,14-Dihydro-15-keto-PGE2[1].
|
-
-
- HY-N6787S
-
|
5,6-Dihydro-5-methyluracil-d6 is the deuterium labeled 5,6-Dihydro-5-methyluracil. 5,6-Dihydro-5-methyluracil (Dihydrothymine), an intermediate breakdown product of thymine, comes from animal or plants. 5,6-Dihydro-5-methyluracil (Dihydrothymine) can be toxic when present at abnormally high levels[1].
|
-
-
- HY-W319671S
-
|
2-Methoxy-4,5-dihydro-1H-imidazole-d4 is the deuterium labeled 2-Methoxy-4,5-dihydro-1H-imidazole[1].
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-
-
- HY-W756041
-
|
rel-(1S,2S)-Dihydro bupropion-d9 hydrochloride is the deuterium labeled rel-(1S,2S)-Dihydro bupropion hydrochloride.
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-
-
- HY-113208AS1
-
|
11β-13,14-Dihydro-15-keto Prostaglandin F2α-d4 is is the deuterium labeled 11β-13,14-dihydro-15-keto Prostaglandin F2α.
|
-
-
- HY-W867679S
-
|
5,12-Dihydro-12-phenylindolo[3,2-a]carbazole-d16 is a deuterium labeled compound.
|
-
-
- HY-W745349
-
|
rel-(1S,2R)-Dihydro bupropion-d9 hydrochloride is the deuterium labeled rel-(1S,2R)-Dihydro bupropion hydrochloride .
|
-
-
- HY-139968S
-
|
13,14-Dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 is the deuterium labeled 13,14-Dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1[1].
|
-
-
- HY-105000S1
-
|
trans-Dihydro Tetrabenazine-d7 is deuterium labeled (2S,3S,11bS)-3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol.
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-
-
- HY-W140284S
-
|
6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate-d8 (hydrochloride) is the deuterium labeled 6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate hydrochloride[1].
|
-
-
- HY-146708S
-
|
((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- 15N4 (sodium) is a 15N-labeled ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate (so
|
-
-
- HY-135794S
-
|
11-Ketodihydrotestosterone-d3 is the deuterium labeled 11-Ketodihydrotestosterone. 11-Ketodihydrotestosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a Ki of 20.4 nM and an EC50 of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells[1][2].
|
-
Cat. No. |
Product Name |
Application |
Reactivity |
-
- HY-P81140
-
8-hydroxy-2'-deoxyguanosine; 2'-Deoxy-8-oxoguanosine; 7,8-dihydro-8-oxo-2'-deoxyguanosine; 8-Oxo-7,8-dihydro-2'-deoxyguanosine; 8-Oxo-7,8-dihydrodeoxyguanosine; 2'-Deoxy-8-oxo-D-guanosine; 8-Oxo-7,8-dihydro-2μ-deoxyguanosine,8-Oxo-dG; 2'-Deoxy-8-hydroxyguanosine;
|
ELISA; IHC-P; IHC-F; IF
|
Human |
8-OHdG (DNA/RNA Damage) Antibody is an unconjugated, approximately 0.283 kDa, rabbit-derived, anti-8-OHdG (DNA/RNA Damage) polyclonal antibody. 8-OHdG (DNA/RNA Damage) Antibody can be used for: ELISA, IHC-P, IHC-F, IF expriments in human, background without labeling.
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Cat. No. |
Product Name |
|
Classification |
-
- HY-152352
-
|
|
Alkynes
|
7,8-Dihydro-8-oxo-7-propargyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-154284
-
|
|
Alkynes
|
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-152338
-
|
|
Alkynes
|
7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-152364
-
|
|
Alkynes
|
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-152373
-
|
|
Alkynes
|
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-154283
-
|
|
Alkynes
|
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-154425
-
|
|
Alkynes
|
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
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