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Targets Recommended: NEDD8-activating Enzyme

Results for "74252-25-8" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-14397A
    Indomethacin sodium hydrate

    Indometacin sodium hydrate

    COX Autophagy Cancer Inflammation/Immunology
    Indomethacin sodium hydrate (Indometacin sodium hydrate) is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells. Indomethacin sodium hydrate disrupts autophagic flux by disturbing the normal functioning of lysosomes.