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Results for "

80s ribosome Inhibitors

" in MCE Product Catalog:

By Targets:	Antibiotic (1) Apoptosis (1) Bacterial (1) DNA/RNA Synthesis (1) JNK (1) Parasite (1) Ser/Thr Protease (2)
By Research Areas:	Cancer (2) Cardiovascular Disease (2) Infection (1)

3

Inhibitors & Agonists

1

MCE Kits

1

Natural
Products

Cat. No.	Product Name	Target	Research Areas

R-IMPP PF-00932239	Ser/Thr Protease	Cancer Cardiovascular Disease
R-IMPP (PF-00932239) is an anti-secretagogue of PCSK9 (IC₅₀=4.8 μM), which targets the 80S ribosome to inhibit PCSK9 protein translation.

Anisomycin 45+ Cited Publications Flagecidin; Wuningmeisu C	DNA/RNA Synthesis JNK Bacterial Apoptosis Antibiotic Parasite	Cancer Infection
Anisomycin is a potent protein synthesis inhibitor which interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. Anisomycin is a JNK activator, which increases phospho-JNK. Anisomycin is a bacterial antibiotic.

PF-06446846	Ser/Thr Protease	Cardiovascular Disease
PF-06446846 is an orally active proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. PF-06446846 directly and selectively inhibits translation of PCSK9 by stalling the 80S ribosome in the proximity of codon region.

Cat. No.	Product Name

G418 Selective Antibiotic, Sterile 2 Publications Verification
MCE G418 Selective Antibiotic, Sterile is an aminoglycoside antibiotic produced by Micromonospora rhodorangea. It acts by binding to the 80S subunit of the bacterial ribosome, thus inhibiting protein synthesis in both prokaryotic and eukaryotic cells.

Cat. No.	Product Name	Target	Category

Anisomycin 45+ Cited Publications Flagecidin; Wuningmeisu C	DNA/RNA Synthesis JNK Bacterial Apoptosis Antibiotic Parasite	Structural Classification Antibiotics Antibacterial Disease Research Other Antibiotics Microorganisms Source classification Infection Disease Research Fields Classification of Application Fields
Anisomycin is a potent protein synthesis inhibitor which interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. Anisomycin is a JNK activator, which increases phospho-JNK. Anisomycin is a bacterial antibiotic.

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