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Targets Recommended: PI4K MAP4K Oct3/4 FXR Serotonin Transporter

Results for "847249-57-4" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-138831

    HDAC Cancer
    AES-350 is a potent and orally active HDAC6 inhibitor with an IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively. AES-350 is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, and >1μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.