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" in MCE Product Catalog:
Targets Recommended: NEDD8-activating Enzyme
Cat. No. Product Name Target Research Areas
  • HY-10454


    Proteasome NF-κB Apoptosis Cancer
    Delanzomib (CEP-18770) is a potent and orally active chymotrypsin-like activity of the proteasome inhibitor with an IC50 of 3.8 nM. Delanzomib inhibits NF-κB activity, induces cancer cell apoptotic, and has strong antiangiogenic and anti-cancer activities.