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Targets Recommended: NEDD8-activating Enzyme

Results for "862505-00-8" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-13241A
    Ralimetinib

    LY2228820

    p38 MAPK Autophagy Cancer Inflammation/Immunology
    Ralimetinib (LY2228820) is a potent and selective, ATP-competitive inhibitor of p38 MAPK α/β, with IC50s of 5.3 and 3.2 nM, respectively. Ralimetinib (LY2228820) selectively inhibits phosphorylation of MK2 (Thr334), with no effect on phosphorylation of p38α MAPK, JNK, ERK1/2, c-Jun, ATF2, or c-Myc.