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87-11-6

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6712
    Thiolutin
    2 Publications Verification

    Acetopyrrothin

    		 Bacterial Antibiotic Endogenous Metabolite Deubiquitinase Infection Metabolic Disease
    Thiolutin (Acetopyrrothin) is a disulfide-containing antibiotic and anti-angiogenic compound produced by Streptomyces. Thiolutin inhibits the JAMM metalloproteases Csn5, Associated-molecule-with-the-SH3-Domain-of-STAM (AMSH) and Brcc36 . Thiolutin is a potent and selective inhibitor of endothelial cell adhesion accompanied by rapid induction of Heat-shock protein beta-1 (Hsp27) phosphorylation .
    Thiolutin

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