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" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-15023
    3 Publications Verification


    Oxytocin Receptor Endocrinology
    Cligosiban (PF-3274167), a high oral bioavailability and good brain-penetrant non-peptide oxytocin receptor antagonist, shows a high-affinity (Ki=9.5 nM) and an excellent selectivity versus the vasopressin receptors with almost no affinity for the V1b and V1a subtypes. Cligosiban inhibits ejaculatory physiology in rodents.