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Results for "913822-46-5" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-10496
    SC75741

    NF-κB Caspase Influenza Virus Infection
    SC75741 is a broad and efficient NF-κB inhibitor with an IC50 of 200 nM for p65. SC75741 blocks influenza viruses (IV) replication in non-toxic concentrations. SC75741 impairs DNA binding of the NF-κB subunit p65, resulting in reduced expression of cytokines, chemokines, and pro-apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase-mediated nuclear export of viral ribonucleoproteins.