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" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-18351

    LMP-400; NSC-724998

    Topoisomerase Cancer Infection
    Indotecan (LMP-400), an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis.