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" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-12113

    ONX 0912; PR-047

    Proteasome Autophagy Cancer
    Oprozomib (PR-047) is an orally bioavailable and selective peptide epoxyketone proteasome inhibitor with IC50s of 36 and 82 nM for proteasome (β5) and immunoproteasome (LMP7), respectively. Oprozomib (ONX 0912) induces apoptosis in MM cells.