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Results for "

ABHD11

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18544
    AA38-3

    		MAGL FAAH Metabolic Disease
    AA38-3 is a serine hydrolase (SH) inhibitor. AA38-3 can inhibit three SHs, ABHD6, ABHD11, and FAAH .
    AA38-3
  • HY-128035
    ML-211

    		Phospholipase MAGL
    ML-211 is a carbamate-based dual inhibitor of acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) (IC50=17 nM) and LYPLA2 (IC50=30 nM). ML-211 also inhibits theserine hydrolase ABHD11 with an IC50 value of 10 nM but is ≥ 50-fold selective for LYPLA in a panel of 20 additional serine hydrolases .
    ML-211
  • HY-18540
    KT109

    		MAGL Metabolic Disease Inflammation/Immunology
    KT109 is a potent and an isoform-selective inhibitor of diacylglycerol lipase-β (DAGLβ) with an IC50 of 42 nM. KT109 has ~60-fold selectivity for DAGLβ over DAGLα. KT109 shows inhibitory activity against PLA2G7 (IC50=1 µM). KT109 shows negligible activity against FAAH, MGLL, ABHD11, and cytosolic phospholipase A2 (cPLA2 or PLA2G4A). KT109 perturbs a lipid network involved in macrophage inflammatory responses and lowers 2-arachidonoylglycerol (2-AG), arachidonic acid and eicosanoids in mouse peritoneal macrophages .
    KT109
  • HY-RS00085
    ABHD11 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    ABHD11 Human Pre-designed siRNA Set A contains three designed siRNAs for ABHD11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ABHD11 Human Pre-designed siRNA Set A
    ABHD11 Human Pre-designed siRNA Set A
  • HY-129121
    ML-​226

    		MAGL Neurological Disease
    ML226 is a potent α/β hydrolase domain-containing protein 11 (ABHD11) inhibitor in vitro and in situ with IC50s of 15 and 0.68 nM, respectively .
    ML-​226

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