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ACA

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

3

Peptides

1

Natural
Products

10

Recombinant Proteins

1

Antibodies

2

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-118628
    N-(p-amylcinnamoyl) Anthranilic Acid
    2 Publications Verification

    ACA

    Phospholipase TRP Channel Cardiovascular Disease
    N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker . N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is also an effective reversible inhibitor of calcium-activated chloride channels, has potential to treat arrhythmia .
    N-(p-amylcinnamoyl) Anthranilic Acid
  • HY-147855

    ERK Apoptosis Cancer
    ACA-28 (compound 2a) is a potent ERK MAPK signaling modulator. ACA-28 selectively inhibits cancer cell growth by inducing apoptosis with ERK hyperactivation ACA-28 inhibits cell growth of melanoma cells (SK-MEL-28) and normal melanocytes (NHEM), with IC50 values of 5.3 and 10.1 μM, respectively .
    <em>ACA</em>-28
  • HY-B1434
    7-Aminocephalosporanic acid
    1 Publications Verification

    7-ACA

    Beta-lactamase Bacterial Antibiotic Infection
    7-aminocephalosporanic acid (7-ACA) is a HSP90β inhibitor and an antibiotic. 7-Aminocephalosporanic acid is the core chemical structure of the synthesis of cephalosporin antibiotics and an effective β-lactamase inhibitor .
    7-Aminocephalosporanic acid
  • HY-151861

    ADC Linker Others
    N3-Aca-Aca-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
    N3-<em>Aca</em>-<em>Aca</em>-OH
  • HY-151787

    ADC Linker Others
    Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution .
    Fmoc-L-Lys(N3-<em>Aca</em>-DIM)-OH
  • HY-162321

    Ras Cancer
    ZINC57632462 (ACA-6) is a non-covalent allosteric KRAS inhibitor. ZINC57632462 disrupts nucleotide exchange and inhibits RAS-effector interaction. ZINC57632462 can be used for the research of cancer .
    ZINC57632462
  • HY-E70137

    Others Others
    AMG 118 Immobilized cephalosporin C acylase is an enzyme that catalyzes in immobilized form and is generally used in industrial catalytic production of the important pharmaceutical intermediate 7-aminocephalosporanic acid (7-ACA). It contains CPC acylase, a highly specialized beta-lactam acylase or peptidase that cleaves the amide bonds between beta-lactams .
    AMG 118 (Immobilized cephalosporin C acylase)
  • HY-P4832

    Amyloid-β Neurological Disease
    Acetyl-Tau Peptide (273-284) amide is an acetylated Tau peptide fragment. Acetyl-Tau Peptide (273-284) amide limits the substantial aggregation of Ac-Aβ(25–35)-NH2 and can be used as an inhibitor of Ac-Aβ(25–35)-NH2. Acetyl-Tau Peptide (273-284) amide can be used as an experimental model to investigate the Aβ/Tau cross-interaction .
    Acetyl-Tau Peptide (273-284) amide
  • HY-34887

    Others Others
    Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM .
    Acridone-4-carboxylic acid
  • HY-150014

    Others Others
    AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells .
    AMT-NHS

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