ADA

By Targets:	Adenosine Deaminase (5) Antibiotic (1) Bacterial (1) Biochemical Assay Reagents (1) CCR (1) Endogenous Metabolite (1) HIV (1) Influenza Virus (1) Isotope-Labeled Compounds (2) Phosphodiesterase (PDE) (1) Small Interfering RNA (siRNA) (4)
By Research Areas:	Cancer (5) Cardiovascular Disease (3) Endocrinology (1) Infection (3) Inflammation/Immunology (2) Neurological Disease (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0855

ADA

Biochemical Assay Reagents Others

ADA is a biological buffer . ADA can serve as a chelator .

*ADA*	Biochemical Assay Reagents	Others
ADA is a biological buffer . ADA can serve as a chelator .

HY-RS00258

ADA Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ADA Human Pre-designed siRNA Set A contains three designed siRNAs for ADA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ADA Human Pre-designed siRNA Set A ADA Human Pre-designed siRNA Set A

HY-RS00259

Ada Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ada Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ada gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ada Mouse Pre-designed siRNA Set A Ada Mouse Pre-designed siRNA Set A

HY-RS00260

Ada Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ada Rat Pre-designed siRNA Set A contains three designed siRNAs for Ada gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ada Rat Pre-designed siRNA Set A Ada Rat Pre-designed siRNA Set A

HY-RS00261

ADA2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ADA2 Human Pre-designed siRNA Set A contains three designed siRNAs for ADA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ADA2 Human Pre-designed siRNA Set A ADA2 Human Pre-designed siRNA Set A

HY-103160A

EHNA hydrochloride 3 Publications Verification	Adenosine Deaminase Phosphodiesterase (PDE) Influenza Virus	Infection Cardiovascular Disease Neurological Disease Cancer
EHNA hydrochloride is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2)(IC₅₀=4 μM) and adenosine deaminase (ADA). EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)(IC₅₀:0.8 μM (human), 2 μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA hydrochloride play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects .

HY-117260

Coformycin	Adenosine Deaminase Bacterial Antibiotic	Infection Cancer
Coformycin, a nucleoside antibiotic, is a potent inhibitor of adenosine deaminase (ADA) from Streptomyces species. Coformycin possesses anti-tumor and anti-bacterial activity .

HY-N7368

Hibifolin	Adenosine Deaminase	Neurological Disease Inflammation/Immunology Cancer
Hibifolin, a flavonol glycoside, is a potential inhibitor of adenosine deaminase (ADA), with a K_i of 49.92 μM. Hibifolin protects neurons against beta-amyloid-induced neurotoxicity .

HY-116578

Metopimazine EXP999; RP9965	Others	Inflammation/Immunology
Metopimazine (EXP999) is a phenothiazine derivative used to prevent emesis during chemotherapy. Metopimazine belongs to the anti-dopaminergic anti-emetics (ADA) class. Metopimazine can be used for the research of gastroenteritis (GE) .

HY-W011552

2'-O-Methyladenosine	Endogenous Metabolite	Cardiovascular Disease
2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities .

HY-103159

1-Deazaadenosine	Adenosine Deaminase	Cancer
1-Deazaadenosine is a potent Adenosine deaminase (ADA) inhibitor with a K_i value of 0.66 μM. 1-Deazaadenosine exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders .

HY-103237

L-Adenosine	Adenosine Deaminase	Neurological Disease
L-Adenosine is a metabolically stable enantiomeric analog and also is a potential probe. L-Adenosine has weakly inhibitory adenosine deaminase (ADA) activity with an K_i value of 385 μM. L-Adenosine can be used for the research of adenosine uptake and accumulation .

HY-158009

SGF29-IN-1	Others	Cancer
SGF29-IN-1 (Compound Cpd_DC60) is a selective inhibitor for Spt-Ada-Gcn5 acetyltransferase (SAGA)–associated factor 29 (SGF29)-Tudor domain. SGF29-IN-1 exhibits activity against leukemia .

HY-P5201S

VTSEGAGLQLQK-13C6,15N2	Isotope-Labeled Compounds	Others
VTSEGAGLQLQK- ¹³C₆, ¹⁵N₂ is the ¹³C and ¹⁵N labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA). VTSEGAGLQLQK can be used to bind anti-drug antibodies (ADA) in plasma and quantitatively analyze the therapeutic effect .

HY-17377

Vicriviroc maleate SCH-417690 maleate; SCH-D maleate	CCR HIV	Infection Endocrinology
Vicriviroc maleate (SCH-417690 maleate; SCH-D maleate) is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5, with a K_i of 2.5 nM, and also inhibits HIV-1 in PBMC cells, with IC₉₀s of 3.3 nM (JrFL), 2.8 nM (ADA-M), 1.8 nM (301657), 4.9 nM (JV1083) and 10 nM (RU 570).

HY-W753672

2'-O-Methyladenosine-d3	Isotope-Labeled Compounds	Cardiovascular Disease
2'-O-Methyl Adenosine-d₃ is deuterium labeled 2'-O-Methyl Adenosine. 2'-O-Methyl Adenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyl Adenosine exhibits unique hypotensive activities .

Cat. No.	Product Name	Type

HY-D0855

ADA

Biochemical Assay Reagents

ADA is a biological buffer . ADA can serve as a chelator .

*ADA*	Biochemical Assay Reagents
ADA is a biological buffer . ADA can serve as a chelator .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7368

Hibifolin	Flavonols Flavonoids other families Classification of Application Fields Neurological Disease Source classification Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology	Adenosine Deaminase
Hibifolin, a flavonol glycoside, is a potential inhibitor of adenosine deaminase (ADA), with a K_i of 49.92 μM. Hibifolin protects neurons against beta-amyloid-induced neurotoxicity .

HY-W011552

2'-O-Methyladenosine	Cardiovascular Disease Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities .

HY-117260

Coformycin	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Anticancer Disease Research Fields Other Antibiotics	Adenosine Deaminase Bacterial Antibiotic
Coformycin, a nucleoside antibiotic, is a potent inhibitor of adenosine deaminase (ADA) from Streptomyces species. Coformycin possesses anti-tumor and anti-bacterial activity .

Species:	Human (2)
Tag:	His (2)
Source:	Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P76250

	CECR1 Protein, Human (sf9, His) Adenosine deaminase 2; ADA2; ADGF; CECR1; IDGFL	Human	Sf9 insect cells
	CECR1, an adenosine deaminase, degrades extracellular adenosine, a pivotal signaling molecule, with activity dependent on elevated adenosine levels. It binds cell surfaces through proteoglycans, hinting at roles in cell proliferation and differentiation beyond its enzyme function. This dual functionality highlights its potential significance in cellular regulatory processes. CECR1 Protein, Human (sf9, His) is the recombinant human-derived CECR1 protein, expressed by Sf9 insect cells, with C-His labeled tag. The total length of CECR1 Protein, Human (sf9, His) is 511 a.a., with molecular weight of ~58 KDa.

HY-P74429

	*Adenosine Deaminase/ADA* Protein, Human (sf9, His)** Adenosine deaminase; ADA; ADA1	Human	Sf9 insect cells
	The adenosine deaminase/ADA protein catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine, which is critical for purine metabolism and adenosine homeostasis. It affects cell signaling indirectly by regulating extracellular adenosine. Adenosine Deaminase/ADA Protein, Human (sf9, His) is the recombinant human-derived Adenosine Deaminase/ADA protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Adenosine Deaminase/ADA Protein, Human (sf9, His) is 363 a.a., with molecular weight of ~44 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-P5201S

VTSEGAGLQLQK-13C6,15N2
VTSEGAGLQLQK- ¹³C₆, ¹⁵N₂ is the ¹³C and ¹⁵N labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA). VTSEGAGLQLQK can be used to bind anti-drug antibodies (ADA) in plasma and quantitatively analyze the therapeutic effect .

HY-W753672

2'-O-Methyladenosine-d3
2'-O-Methyl Adenosine-d₃ is deuterium labeled 2'-O-Methyl Adenosine. 2'-O-Methyl Adenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyl Adenosine exhibits unique hypotensive activities .

Cat. No.	Product Name	Application	Reactivity

HY-P82862

Adenosine Deaminase Antibody (YA2607)

ADA; ADA1
WB, ICC/IF, IP Human, Rat

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Inhibitors & Agonists

Biochemical Assay Reagents

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Recombinant Proteins

Isotope-Labeled Compounds

Antibodies