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Results for "

ADP

" in MedChemExpress (MCE) Product Catalog:

By Targets:	PARP (26) Poly(ADP-ribose) Glycohydrolase (PARG) (11) Adenosine Receptor (3) Adenylate Cyclase (2) Adrenergic Receptor (1) Apoptosis (11) Arrestin (2) ATP Citrate Lyase (1) ATP Synthase (1) Autophagy (1) Bacterial (6) Bcl-2 Family (1) Biochemical Assay Reagents (3) Calcium Channel (2) Caspase (2) Cathepsin (1) CD38 (1) CDK (1) CFTR (1) CMV (1) Cytochrome P450 (3) DNA/RNA Synthesis (6) Drug Metabolite (2) Endogenous Metabolite (29) Enterovirus (1) Fluorescent Dye (2) Fungal (2) GSK-3 (1) HCV (1) HSV (1) Integrin (1) Isotope-Labeled Compounds (5) JAK (1) Myosin (1) NF-κB (1) NO Synthase (1) Nucleoside Antimetabolite/Analog (8) P-selectin (1) P2Y Receptor (25) PGE synthase (1) Phosphodiesterase (PDE) (1) PPAR (1) PROTACs (1) Pyruvate Kinase (1) RIP kinase (1) SARS-CoV (1) Src (1) STAT (1) Syk (1) Toll-like Receptor (TLR) (1) TRP Channel (2) ULK (1)
By Research Areas:	Cancer (52) Cardiovascular Disease (35) Endocrinology (6) Infection (11) Inflammation/Immunology (17) Metabolic Disease (21) Neurological Disease (12)
Click Chemistry:	Azide (1)

170

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Targets Recommended: Poly(ADP-ribose) Glycohydrolase (PARG) PARP

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W010918

Adenosine 5'-diphosphate Adenosine diphosphate; ADP	Endogenous Metabolite	Others
Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-134354A

pNP-ADPr disodium ADP-ribose-pNP disodium	Poly(ADP-ribose) Glycohydrolase (PARG)	Others
pNP-ADPr disodium is a colorimetric substrate that used for the first continuous Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activity assays. pNP-ADPr disodium can be used for the research of poly(ADP-ribose)polymerase (PARP) enzymes .

HY-100973A

Adenosine 5′-diphosphoribose sodium 2 Publications Verification ADP ribose sodium
Adenosine 5′-diphosphoribose sodium (ADP ribose sodium) is a nicotinamide adenine nucleotide (NAD ⁺) metabolite. Adenosine 5′-diphosphoribose sodium is the most potent and primary intracellular Ca ²⁺-permeable cation TRPM2 channel activator. Adenosine 5′-diphosphoribose sodium also can enhance autophagy .

HY-134354

pNP-ADPr ADP-ribose-pNP	Poly(ADP-ribose) Glycohydrolase (PARG)	Others
pNP-ADPr is a colorimetric substrate that used for the first continuous Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activity assays. pNP-ADPr can be used for the research of poly(ADP-ribose)polymerase (PARP) enzymes .

HY-136830

ADP-Glucose disodium Adenosine-5'-diphosphoglucose disodium	Biochemical Assay Reagents	Others
ADP-Glucose disodiumIs an immediate precursor for the biosynthesis of storage polysaccharides in plants, green algae and cyanobacteria, and structural polysaccharides in some bacteria, by the addition of glucose. It is used to produce amylose, amylopectin, starch and other polysaccharides by amylose synthase or starch synthase in plastids. ADPGUsually produced in plastids, although it can be biosynthesized in the cytoplasm of some grasses and imported into plastids by membrane-bound transporters .

HY-W010918S

Adenosine 5'-diphosphate-d13 dilithium Adenosine diphosphate-d¹³ dilithium; ADP--d¹³ dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Others
Adenosine 5'-diphosphate-d₁₃ (Adenosine diphosphate-d₁₃ dilithium; ADP-d₁₃) dilithium is deuterium labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-W010918S1

Adenosine 5'-diphosphate-13C10 dilithium Adenosine diphosphate-¹³C₁₀ dilithium; ADP-¹³C₁₀ dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Others
Adenosine 5'-diphosphate- ¹³C₁₀ (Adenosine diphosphate- ¹³C₁₀ dilithium; ADP- ¹³C₁₀) dilithium is ¹³C-labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-W010918S2

Adenosine 5'-diphosphate-15N5 dilithium Adenosine diphosphate-¹⁵N₅ dilithium; ADP-¹⁵N₅ dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Others
Adenosine 5'-diphosphate- ¹⁵N₅ (Adenosine diphosphate- ¹⁵N₅ dilithium; ADP- ¹⁵N₅) dilithium is ¹⁵N labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-15904

ADPS ESPAS	Biochemical Assay Reagents	Others
ADPS is a kind of new Trinder's reagents, which are high water-soluble aniline derivatives, widely used in diagnostic and biochemical tests.

HY-N7395

*Cyclic ADP-ribose* cADPR	Calcium Channel TRP Channel Endogenous Metabolite	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Endocrinology
Cyclic ADP-ribose (cADPR) is a potent second messenger for calcium mobilization that is synthesized from NAD ⁺ by an ADP-ribosyl cyclase. Cyclic ADP-ribose increases cytosolic calcium mainly by Ryanodine receptor-mediated release from endoplasmic reticulum and also by extracellular influx through the opening of TRPM2 channels .

HY-134318B

*8-Azido-ADP* disodium**	DNA/RNA Synthesis	Others
8-Azido-ADP (disodium) is a covalent-binding inhibitor of mitochondrial adenine nucleotide translocation. 8-Azido-ADP (disodium) causes irreversible inhibition of adenine nucleotide exchange in a light-dependent reaction. 8-Azido-ADP (disodium) inhibits the normal state 4 → 3 transitions of mitochondrial respiration induced by ADP . 8-Azido-ADP (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-N7395A

*Cyclic ADP-ribose ammonium* cADPR ammonium	Calcium Channel TRP Channel Endogenous Metabolite	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Endocrinology
Cyclic ADP-ribose ammonium (cADPR ammonium) is a potent second messenger for calcium mobilization that is synthesized from NAD ⁺ by an ADP-ribosyl cyclase. Cyclic ADP-ribose ammonium increases cytosolic calcium mainly by Ryanodine receptor-mediated release from endoplasmic reticulum and also by extracellular influx through the opening of TRPM2 channels .

HY-146248

TFMU-ADPr	Poly(ADP-ribose) Glycohydrolase (PARG)	Others
TFMU-ADPr is a general substrate for monitoring poly(ADP-ribose) glycohydrolase (PARG) activity. TFMU-ADPr can directly report on total PAR hydrolase activity via release of a fluorophore. TFMU-ADPr has excellent reactivity, generality, stability, and usability. TFMU-ADPr is a versatile tool for assessing small-molecule inhibitors in vitro and probing the regulation of ADP-ribosyl catabolic enzymes .

HY-146248A

TFMU-ADPr triethylamine	Poly(ADP-ribose) Glycohydrolase (PARG)	Others
TFMU-ADPr triethylamine is a general substrate for monitoring poly(ADP-ribose) glycohydrolase (PARG) activity. TFMU-ADPr triethylamine can directly report on total PAR hydrolase activity via release of a fluorophore. TFMU-ADPr triethylamine has excellent reactivity, generality, stability, and usability. TFMU-ADPr triethylamine is a versatile tool for assessing small-molecule inhibitors in vitro and probing the regulation of ADP-ribosyl catabolic enzymes .

HY-112658

p-Iodoclonidine hydrochloride	Adrenergic Receptor Adenosine Receptor	Endocrinology
p-Iodoclonidine hydrochloride is a partial agonist of α2-adrenergic receptor. p-Iodoclonidine hydrochloride also has minimal agonist activity in inhibiting adenylate cyclase in platelet membranes, and potentiates ADP induced platelet aggregation with an EC₅₀ of 1.5 μM .

HY-107867

(±)-Clopidogrel bisulfate	Others	Cardiovascular Disease
Clopidogrel sulfate is an antiplatelet agent. Specifically, Clopidogrel sulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. Clopidogrel sulfate can be used for research of heart disease and stroke .

HY-E70238

2-Azido-NAD Nicotinamide 2-azidoadenine dinucleotide	Others	Others
2-Azido-NAD is a NAD ⁺ analog that can be used for visualization of intracellular Poly(ADP ribos)ylation (PARylation) processes .

HY-N7614

Anemarrhenasaponin A2 Schidigerasaponin F2; Timosaponin AII	Others	Cardiovascular Disease
Anemarrhenasaponin A2 (Schidigerasaponin F2) is a steroidal saponin isolated from the rhizomes of Anemarrhena asphodeloides. Anemarrhenasaponin A2 inhibits ADP-induced platelet aggregation .

HY-15284

Prasugrel PCR 4099	P2Y Receptor	Cardiovascular Disease
Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .

HY-15284A

Prasugrel hydrochloride PCR 4099 hydrochloride	P2Y Receptor	Cardiovascular Disease
Prasugrel hydrochloride (PCR 4099 hydrochloride), a thienopyridine and proagent, inhibits platelet function. Prasugrel hydrochloride is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .

HY-137591

13,14-Dihydro-15-keto-PGE1	Others	Endocrinology
13,14-Dihydro-15-keto-PGE1 is an inactive metabolite of PGE1. 13, 14-Dihydro-15-Keto-pGE1 inhibited platelet aggregation in ADP-induced human isolated platelet-rich plasma with IC₅₀ 14.8 μg/mL .

HY-136501

MRS2395	P2Y Receptor	Cardiovascular Disease
MRS2395, an dipivaloyl derivative, is a potent P2Y12 receptor antagonist. MRS2395 inhibits ADP-induced platelet activation with a K_i of 3.6 μM. MRS2395 inhibits cAMP induced by ADP in rat platelets in the presence of PGE1 with an IC₅₀ of 7 µM. MRS2395 enhances platelet dense granule release in response to TRAP-6 .

HY-15284B

Prasugrel (Maleic acid) PCR 4099 (Maleic acid)	P2Y Receptor	Cardiovascular Disease
Prasugrel (PCR 4099) Maleic acid is a thienopyridine and proagent, inhibits platelet function. Prasugrel Maleic acid is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .

HY-134216

MAHMA NONOate	Endogenous Metabolite NO Synthase	Cardiovascular Disease
MAHMA NONOate is a NO donor. MAHMA NONOate effectively inhibits platelet aggregation induced by either collagen or ADP .

HY-N10272

Avenaciolide	Fungal Bacterial	Infection
Avenaciolide is an antifungal bis-γ-lactone found in Aspergillus avenaceus. Avenaciolide has also antibacterial action. Avenaciolide is a specific inhibitor of glutamate transport in rat liver mitochondria. Avenaciolide interferes with the ability of ADP to stimulate the rate of glutamate oxidation .

HY-108665

AR-C66096 tetrasodium FPL 66096 tetrasodium; PSFM-ATP tetrasodium	Biochemical Assay Reagents	Cardiovascular Disease
AR-C66096 tetrasodium is a selective platelet P2Y_T receptor antagonist. AR-C66096 tetrasodium effectively blocks ADP-induced platelet aggregation. AR-C66096 tetrasodium can be used in the research of thromboembolism .

HY-113723

MRS2298	P2Y Receptor	Cardiovascular Disease
MRS2298? is a potent acyclic P2Y1 receptor antagonist with a K_i of 29.6 nM. MRS2298 inhibits the ADP-induced aggregation of human platelets with an IC₅₀ of 62.8 nM. MRS2298 inhibits Ca ²⁺ rise in platelets with an IC₅₀ of 810 nM .

HY-134266

8-Bromo-AMP 1 Publications Verification 8-Bromoadenosine 5'-monophosphate; 8-Bromoadenylic acid	Others	Cardiovascular Disease
8-Bromo-AMP (8-Bromoadenosine 5'-monophosphate) is a membrane permeable cAMP analogue. 8-Bromo-AMP can improve the ability of the heart to recover from ischemia and reperfusion by increasing the levels of ATP, ADP, and total adenine nucleotides .

HY-125989

2-Methylthio-AMP 1 Publications Verification 2-MeSAMP; 2-Methylthioadenosine 5′-monophosphate; 2-Methylthioadenosine 5′-phosphate	P2Y Receptor	Cardiovascular Disease
2-Methylthio-AMP (2-MeSAMP) is a selective and direct P2Y₁₂ antagonist. 2-Methylthio-AMP is an inhibitor of ADP-dependent platelet aggregation .

HY-125989B

2-Methylthio-AMP diTEA 2-MeSAMP diTEA; 2-Methylthioadenosine 5′-monophosphate diTEA; 2-Methylthioadenosine 5′-phosphate diTEA	P2Y Receptor	Cardiovascular Disease
2-Methylthio-AMP (2-MeSAMP) diTEA is a selective and direct P2Y₁₂ antagonist. 2-Methylthio-AMP diTEA is an inhibitor of ADP-dependent platelet aggregation .

HY-18740A

Trequinsin hydrochloride HL 725	Phosphodiesterase (PDE)	Metabolic Disease
Trequinsin hydrochloride (HL 725) is an extremely potent inhibitor of platelet CAMP phosphodiesterase (PDE), with an IC₅₀ of 0.25 nM. Trequinsin hydrochloride (HL 725) is an extremely potent inhibitor of the aggregation of human platelets induced in vitro by ADP, collagen, thrombin and epinephrine .

HY-108657

MRS2279	P2Y Receptor	Neurological Disease
MRS2279 is a selective and high affinity P2Y1 receptor antagonist, with a K_i of 2.5 nM and an IC₅₀ of 51.6 nM. MRS2279 competitively inhibits ADP-promoted platelet aggregation with an apparent affnity (pK_B=8.05) .

HY-N12070

11-O-β-D-glucopyranosyl thamnosmonin	Others	Cardiovascular Disease
11-O-β-D-glucopyranosyl thamnosmonin, a coumarin glucosides, can be isolated from the roots of Angelica apaensis. 11-O-β-D-glucopyranosyl thamnosmonin has weak inhibitory activity on the aggregation of rabbit platelets induced by PAF, AA, and ADP .

HY-108657A

MRS2279 diammonium 1 Publications Verification	P2Y Receptor	Neurological Disease
MRS2279 diammonium is a selective and high affinity P2Y1 receptor antagonist, with a K_i value of 2.5 nM and an IC₅₀ value of 51.6 nM. MRS2279 diammonium competitively inhibits ADP-promoted platelet aggregation with an pK_b value of 8.05 .

HY-108658

MRS2500 tetraammonium	P2Y Receptor	Cardiovascular Disease
MRS2500 tetraammonium is a potent, selective and stable antagonist of the P2Y1 receptor (K_i=0.78 nM for recombinant human P2Y1 receptor). MRS2500 tetraammonium inhibits the ADP-induced aggregation of human platelets with an IC₅₀ value of 0.95 nM. Antithrombotic activity .

HY-111557

YM-254890 5+ Cited Publications	P2Y Receptor	Cardiovascular Disease
YM-254890 is a selective G_αq/11 protein inhibitor isolated from Chromobacterium sp. YM-254890 shows no inhibition of other G protein subtypes. YM-254890 inhibits platelet aggregation induced by ADP by blocking the P2Y₁ signal transduction pathway, with an IC₅₀ value below 0.6 μM .

HY-N2522

Carboxyatractyloside dipotassium 1 Publications Verification Gummiferin dipotassium	Others	Others
Carboxyatractyloside dipotassium is a toxic natural product, acts as an inhibitor of ADP/ATP carrier, inhibits mitochondrial ADP/ATP transport .

HY-110043

(±)-Clopidogrel hydrochloride	Others	Cardiovascular Disease
(±)-Clopidogrel hydrochloride is an antithrombotic agent that is ADP-selective and orally available. (±)-Clopidogrel hydrochloride inhibits platelet aggregation by inhibiting the binding of ADP to its platelet receptors .

HY-F0001

NADH disodium salt 3 Publications Verification Disodium NADH	Endogenous Metabolite	Metabolic Disease
NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-F0001A

NADH disodium hydrate Disodium NADH hydrate	Endogenous Metabolite	Metabolic Disease
NADH disodium salt (Disodium NADH) hydrate is an orally active reduced coenzyme. NADH disodium salt hydrate is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt hydrate plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-P2799

Creatine phosphokinase, Rabbit muscle CPK	Endogenous Metabolite	Metabolic Disease
Creatine phosphokinase, Rabbit muscle (CPK) catalyzes the reversible reaction of creatine and ATP to form phosphocreatine and ADP. Creatine phosphokinase is a key enzyme for maintaining a constant ATP/ADP ratio during rapid energy turnover .

HY-W250154

β-Nicotinamide adenine dinucleotide reduced dipotassium	Endogenous Metabolite	Metabolic Disease
β-Nicotinamide adenine dinucleotide reduced dipotassium is an orally active reduced coenzyme. β-Nicotinamide adenine dinucleotide reduced dipotassium is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. β-Nicotinamide adenine dinucleotide reduced dipotassium plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-156623

Lerzeparib

PARP Cancer

Lerzeparib is an (ADP-ribose) polymerase (PARP) inhibitor, with antineoplastic activity .

Lerzeparib	PARP	Cancer
Lerzeparib is an (ADP-ribose) polymerase (PARP) inhibitor, with antineoplastic activity .

HY-N1502

Carboxyatractyloside tripotassium 1 Publications Verification Gummiferin tripotassium
Carboxyatractyloside (Gummiferin) tripotassium is a toxic natural product, acts as an inhibitor of ADP/ATP carrier, inhibits mitochondrial ADP/ATP transport from the inner mitochondria to the inner mitochondria. Carboxyatractyloside tripotassium can be used for the study of cellular energy metabolism and mitochondrial biology .

HY-P990037

Erzotabart	CD38	Cancer
Erzotabart is an IgG1-kappa, anti-CD38 (ADP-ribosyl cyclase 1, cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, cADPR1) Homo sapiens monoclonal antibody. Erzotabart shows antineoplastic activity .

HY-147245

Basroparib

STP1002
PARP Cancer

Basroparib is a potent poly (ADP-ribose) polymerase (PARP) inhibitor, with antineoplastic activity .

Basroparib STP1002	PARP	Cancer
Basroparib is a potent *poly (ADP-ribose) polymerase (PARP)* inhibitor, with antineoplastic activity .

HY-P2984

Adenosine triphosphatase	Endogenous Metabolite	Metabolic Disease
Adenosine triphosphatase is an enzyme that catalyzes the decomposition of ATP into ADP and a free phosphate ion (Pi) .

HY-B0153A

Ticlopidine hydrochloride	Adenosine Receptor	Cardiovascular Disease
Ticlopidine hydrochloride is an adenosine diphosphate (ADP) receptor inhibitor against platelet aggregation with IC50 of ~2 μM.

HY-135846

PDD00031705

Poly(ADP-ribose) Glycohydrolase (PARG) Cancer

PDD00031705 is a benzimidazolone core cell-inactive inhibitor of Poly (ADP-ribose) glycohydrolase (PARG) .

HY-P2806

Pyruvate Kinase, Microorganism PK; Fluorokinase	Endogenous Metabolite	Metabolic Disease
Pyruvate Kinase, Microorganism (PK) is a glycolytic enzyme that catalyzes the conversion of phosphoenolpyruvate and ADP to pyruvate and ATP .

Cat. No.	Product Name	Type

HY-15904

ADPS

ESPAS
Biochemical Assay Reagents

ADPS is a kind of new Trinder's reagents, which are high water-soluble aniline derivatives, widely used in diagnostic and biochemical tests.

HY-136830

ADP-Glucose disodium

Adenosine-5'-diphosphoglucose disodium

Biochemical Assay Reagents

ADP-Glucose disodiumIs an immediate precursor for the biosynthesis of storage polysaccharides in plants, green algae and cyanobacteria, and structural polysaccharides in some bacteria, by the addition of glucose. It is used to produce amylose, amylopectin, starch and other polysaccharides by amylose synthase or starch synthase in plastids. ADPGUsually produced in plastids, although it can be biosynthesized in the cytoplasm of some grasses and imported into plastids by membrane-bound transporters .

HY-W250154

β-Nicotinamide adenine dinucleotide reduced dipotassium

Biochemical Assay Reagents

β-Nicotinamide adenine dinucleotide reduced dipotassium is an orally active reduced coenzyme. β-Nicotinamide adenine dinucleotide reduced dipotassium is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. β-Nicotinamide adenine dinucleotide reduced dipotassium plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-P2984

Adenosine triphosphatase

Biochemical Assay Reagents

Adenosine triphosphatase is an enzyme that catalyzes the decomposition of ATP into ADP and a free phosphate ion (Pi) .

HY-E70035

Glucuronokinase (AtGlcAK)	Biochemical Assay Reagents
Glucuronokinase (AtGlcAK) is a member of the GHMP-kinase. Glucuronokinase (AtGlcAK) shows unique substrate specificity for D-glucuronic acid with a K_m value of 0.7 mM. Glucuronokinase (AtGlcAK) catalyzes D-glucuronic acid and ATP to produce D-glucuronic acid-1-phosphate and ADP .

HY-100767

Guanylyl Imidodiphosphate trisodium Guanosine 5'-[β,γ-imido]triphosphate trisodium	Biochemical Assay Reagents
Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010918

Adenosine 5'-diphosphate Adenosine diphosphate; ADP	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease markers Nervous System Disorder Endogenous metabolite Disease Research Fields Cardiovascular System Disorder	Endogenous Metabolite
Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-N7395A

*Cyclic ADP-ribose ammonium* cADPR ammonium	Cardiovascular Disease Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Endocrinology	Calcium Channel TRP Channel Endogenous Metabolite
Cyclic ADP-ribose ammonium (cADPR ammonium) is a potent second messenger for calcium mobilization that is synthesized from NAD ⁺ by an ADP-ribosyl cyclase. Cyclic ADP-ribose ammonium increases cytosolic calcium mainly by Ryanodine receptor-mediated release from endoplasmic reticulum and also by extracellular influx through the opening of TRPM2 channels .

HY-134216

MAHMA NONOate	Cardiovascular Disease Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite NO Synthase
MAHMA NONOate is a NO donor. MAHMA NONOate effectively inhibits platelet aggregation induced by either collagen or ADP .

HY-N7395

*Cyclic ADP-ribose* cADPR	Cardiovascular Disease Natural Products Classification of Application Fields Neurological Disease Source classification Endogenous metabolite Disease Research Fields Inflammation/Immunology Endocrinology	Calcium Channel TRP Channel Endogenous Metabolite
Cyclic ADP-ribose (cADPR) is a potent second messenger for calcium mobilization that is synthesized from NAD ⁺ by an ADP-ribosyl cyclase. Cyclic ADP-ribose increases cytosolic calcium mainly by Ryanodine receptor-mediated release from endoplasmic reticulum and also by extracellular influx through the opening of TRPM2 channels .

HY-N7614

Anemarrhenasaponin A2 Schidigerasaponin F2; Timosaponin AII	Cardiovascular Disease Liliaceae Classification of Application Fields Source classification Anemarrhena asphodeloides Bunge Plants Disease Research Fields Steroids	Others
Anemarrhenasaponin A2 (Schidigerasaponin F2) is a steroidal saponin isolated from the rhizomes of Anemarrhena asphodeloides. Anemarrhenasaponin A2 inhibits ADP-induced platelet aggregation .

HY-N10272

Avenaciolide	Infection Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Fungal Bacterial
Avenaciolide is an antifungal bis-γ-lactone found in Aspergillus avenaceus. Avenaciolide has also antibacterial action. Avenaciolide is a specific inhibitor of glutamate transport in rat liver mitochondria. Avenaciolide interferes with the ability of ADP to stimulate the rate of glutamate oxidation .

HY-N12070

11-O-β-D-glucopyranosyl thamnosmonin	Structural Classification Source classification Coumarins Phenylpropanoids Plants Umbelliferae Angelica apaensis R. H. Shan & C. Q. Yuan	Others
11-O-β-D-glucopyranosyl thamnosmonin, a coumarin glucosides, can be isolated from the roots of Angelica apaensis. 11-O-β-D-glucopyranosyl thamnosmonin has weak inhibitory activity on the aggregation of rabbit platelets induced by PAF, AA, and ADP .

HY-111557

YM-254890 Maximum Cited Publications 7 Publications Verification	Cardiovascular Disease Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	P2Y Receptor
YM-254890 is a selective G_αq/11 protein inhibitor isolated from Chromobacterium sp. YM-254890 shows no inhibition of other G protein subtypes. YM-254890 inhibits platelet aggregation induced by ADP by blocking the P2Y₁ signal transduction pathway, with an IC₅₀ value below 0.6 μM .

HY-N2522

Carboxyatractyloside dipotassium 1 Publications Verification Gummiferin dipotassium	other families Classification of Application Fields Terpenoids Source classification Other Diseases Diterpenoids Plants Disease Research Fields	Others
Carboxyatractyloside dipotassium is a toxic natural product, acts as an inhibitor of ADP/ATP carrier, inhibits mitochondrial ADP/ATP transport .

HY-F0001

NADH disodium salt 3 Publications Verification Disodium NADH	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-W250154

β-Nicotinamide adenine dinucleotide reduced dipotassium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
β-Nicotinamide adenine dinucleotide reduced dipotassium is an orally active reduced coenzyme. β-Nicotinamide adenine dinucleotide reduced dipotassium is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. β-Nicotinamide adenine dinucleotide reduced dipotassium plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-145520

(±)-2'-hydroxy Ceramide (d18:0/18:0) (±)-2'-hydroxy Cer(d18:0/18:0)	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(±)-2'-hydroxy Ceramide (d18:0/18:0) is a sphingomyelin that can be isolated from mammalian platelets stimulation by ADP .

HY-113432

Nudifloramide 2PY	Alkaloids Structural Classification Classification of Application Fields Other disease Source classification Disease markers Pyridine Alkaloids Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite PARP
Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits *poly(ADP-ribose) polymerase (PARP-1)* activity in vitro .

HY-N4266

Vinaginsenoside R8	Cardiovascular Disease Panax ginseng C. A. Meyer Triterpenes Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Araliaceae	Others
Vinaginsenoside R8, a triterpenoid glycoside isolated from the rhizomes of Panacis majoris. Vinaginsenoside R8 displays activities against adenosine diphosphate (ADP)-induced platelet aggregation (IC₅₀=25.18 μM) .

HY-N7765

Oenothein B	Infection Structural Classification other families Classification of Application Fields Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	HCV Bacterial Apoptosis Fungal
Oenothein B is a dimeric macrocyclic ellagitannin and has widely pharmacological activities, including antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties. Oenothein B is a potent and specific inhibitor of *poly(ADP-ribose) glycohydrolase* .

HY-N2374

Eupatorin	Structural Classification Flavonoids Classification of Application Fields Flavones Cruciferae Source classification Phenols Polyphenols Isatis tinctoria L. Plants Disease Research Fields Cancer	Apoptosis
Eupatorin, a naturally occurring flavone, arrests cells at the G2-M phase of the cell cycle and induces apoptotic cell death involving activation of multiple caspases, mitochondrial release of cytochrome c and poly(ADP-ribose) polymerase cleavage .

HY-113371

2-Methylcitric acid Methylcitric acid	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate .

HY-W051513

2-Methylquinazolin-4-ol	Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields	PARP
2-Methylquinazolin-4-ol is a potent competitive *poly(ADP-ribose) synthetase* inhibitor, with a K_i of 1.1 μM. 2-Methylquinazolin-4-ol mammalian aspartate transcarbamylase (ATCase) inhibitor, with 0.20 mM .

HY-W010791

Adenosine 5'-diphosphate sodium salt	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Adenosine 5'-diphosphate (ADP) sodium salt is a nucleoside diphosphate, which is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors .

HY-113371A

2-Methylcitric acid trisodium Methylcitric acid trisodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Methylcitric acid trisodium (Methylcitric acid trisodium) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid trisodium accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid trisodium markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate .

HY-134313A

8-NH2-ATP tetrasodium 8-Aminoadenosine-5'-O-triphosphate tetrasodium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	DNA/RNA Synthesis Endogenous Metabolite
8-NH2-ATP tetrasodium, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado tetrasodium induces apoptosis-related cleavage of poly (ADP-ribose) polymerase .

HY-134313

8-NH2-ATP 8-Aminoadenosine-5'-O-triphosphate	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	DNA/RNA Synthesis Endogenous Metabolite
8-NH2-ATP, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado is reported to be potent as shown by induction of apoptosis-related cleavage of poly (ADP-ribose) polymerase .

HY-134556

2'-Hydroxyflavanone	Structural Classification Flavonoids Mimosa pudica Linn. Leguminosae Flavonones Source classification Plants	Apoptosis
2'-Hydroxyflavanone is a flavanone that can inhibit cancer cell proliferation, induce apoptosis, and reduce inflammation. 2'-Hydroxyflavanone shows inhibitory effect on platelet aggregation caused by two inducers with IC₅₀s 47.8 μM arachidonic acid (AA) and 147.2 μM aenosine diphosphate (ADP) .

HY-N2374R

Eupatorin (Standard)	Structural Classification Flavonoids Classification of Application Fields Cruciferae Source classification Phenols Isatis tinctoria L. Plants Disease Research Fields Cancer	Apoptosis
Eupatorin (Standard) is the analytical standard of Eupatorin. This product is intended for research and analytical applications. Eupatorin, a naturally occurring flavone, arrests cells at the G2-M phase of the cell cycle and induces apoptotic cell death involving activation of multiple caspases, mitochondrial release of cytochrome c and poly(ADP-ribose) polymerase cleavage .

HY-Z0283

Benzamide Benzenecarboxamide; Phenylamide	Structural Classification Alkaloids Human Gut Microbiota Metabolites Classification of Application Fields Other Alkaloids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite PARP
Benzamide (Benzenecarboxamide) is a potent *poly(ADP-ribose) polymerase (PARP)* inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature .

HY-N5021

Anhydrosafflor yellow B AHSYB	Quinones Simple Phenylpropanols Carthamus tinctorius L. Source classification Phenols Polyphenols Benzene Quinones Phenylpropanoids Plants Compositae	Others
Anhydrosafflor yellow B (AHSYB) is a quinochalcone C-glycoside isolated from Carthamus tinctorius. Anhydrosafflor yellow B inhibits ADP-induced platelet aggregation, exhibits significant anti-oxidative effects in vitro, and possesses certain activity against H₂O₂-induced cytotoxicity in cultured PC12 cells and primary neuronal cells .

HY-N10481

Aviculin	Classification of Application Fields Polygonum aviculare L. Polygonaceae Source classification Lignans Phenylpropanoids Plants Disease Research Fields Cancer	Apoptosis Caspase PARP Bcl-2 Family
Aviculin, a lignan glycoside, is a potent anticancer agent. Aviculin reduces metabolic activity on MCF-7 cells below 50%, with an IC₅₀ of 75.47 μM. Aviculin induces breast cancer cell apoptosis through the intrinsic apoptosis pathway. Aviculin increases expression of initiator caspase-9, executioner caspase-7, and poly (ADP-ribose) polymerase (PARP). Aviculin shows an increase in the Bax/Bcl-2 ratio .

HY-N6818

5,7,4'-Trimethoxyflavone	Structural Classification Flavonoids Classification of Application Fields Flavones Source classification Kaempferia parviflora Wall. ex Baker Plants Disease Research Fields Cancer Zingiberaceae	Apoptosis Caspase PARP Endogenous Metabolite CFTR
5,7,4’-Trimethoxyflavone can be isolated from the medicinal plant Kaempferia parviflora (KP). 5,7,4’-Trimethoxyflavone is a CFTR activator and EC₅₀ is 64 μM. 5,7,4’-Trimethoxyflavone induces apoptosis, increases proteolytic activation of caspase-3, and degradation of ADP-ribose polymerase (PARP) protein. 5,7,4’-Trimethoxyflavone has antitumor activity. 5,7,4’-Trimethoxyflavone can be used to prevent skin aging and oxidative stress .

Species:	Human (31) Rat (5) Mouse (6) Cynomolgus (4) Rabbit (1)
Tag:	His (33) Tag Free (3) Strep (1) Avi (2) Myc (2) GST (4) MBP (1) Fc (8) Flag (4)
Source:	HEK293 (24) E. coli Cell-free (2) CHO (1) Sf9 insect cells (5) E. coli (15)

Cat. No.	Compare	Product Name	Species	Source

HY-P72356

	CD38 Protein, Human (Biotinylated, HEK293, His-Avi) ADP-ribosyl cyclase1; 2'-phospho-ADP-ribosyl cyclase; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1	Human	HEK293
	The CD38 protein plays a key role in cell signaling, proficiently synthesizing cyclic ADP-ribose (cADPR) as a critical second messenger for glucose-induced insulin secretion. It also promotes the synthesis of the calcium mobilizer niacin-adenine dinucleotide phosphate (NAADP+). CD38 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD38 protein, expressed by HEK293 , with N-Avi, N-6*His labeled tag. The total length of CD38 Protein, Human (Biotinylated, HEK293, His-Avi) is 258 a.a., with molecular weight of 40-50 kDa.

HY-P702585

	PARP2 Protein, Human (sf9, His) Poly [ADP-ribose] polymerase 2; ADP-ribosyltransferase diphtheria toxin-like 2; DNA ADP-ribosyltransferase PARP2; NAD(+) ADP-ribosyltransferase 2; ADPRT-2; pADPRT-2; EC:2.4.2.30; ADPRT2; ADPRTL2	Human	Sf9 insect cells

HY-P70731

	CD38 Protein, Human (HEK293, His) ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; CD38 antigen; CD38 molecule; CD38	Human	HEK293
	The CD38 protein plays a key role in cell signaling, proficiently synthesizing cyclic ADP-ribose (cADPR) as a critical second messenger for glucose-induced insulin secretion. It also promotes the synthesis of the calcium mobilizer niacin-adenine dinucleotide phosphate (NAADP+). CD38 Protein, Human (HEK293, His) is the recombinant human-derived CD38 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD38 Protein, Human (HEK293, His) is 258 a.a., with molecular weight of 38-50 kDa.

HY-P72896

	CD38 Protein, Rabbit (HEK293, His) ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; ADPRC 1; CD38	Rabbit	HEK293
	CD38 protein performs diverse functions, synthesizing cyclic ADP-ribose (cADPR) for glucose-induced insulin secretion. It produces nicotinate-adenine dinucleotide phosphate (NAADP+), mobilizing calcium ions through 2'-phospho-cADPR and nicotinic acid, along with NADP+ and nicotinic acid. Additionally, CD38 acts as a cADPR hydrolase. CD38 Protein, Rabbit (HEK293, His) is the recombinant Rabbit-derived CD38 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD38 Protein, Rabbit (HEK293, His) is 256 a.a., with molecular weight of 33-49 kDa.

HY-P72897

	CD38 Protein, Rat (HEK293, Fc) ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; ADPRC 1; CD38	Rat	HEK293
	CD38 protein plays diverse roles, synthesizing key second messengers: cyclic ADP-ribose (cADPR) for glucose-induced insulin secretion and nicotinate-adenine dinucleotide phosphate (NAADP) as a calcium mobilizer. Its cADPR hydrolase activity adds to its versatility. Notably, CD38 also regulates osteoclastic bone resorption, likely by producing cADPR and initiating a calcium ion signal through ryanodine receptor activation. CD38 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD38 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD38 Protein, Rat (HEK293, Fc) is 259 a.a., with molecular weight of ~67 kDa.

HY-P70731A

	CD38 Protein, Human (HEK293, C-His) ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; CD38 antigen; CD38 molecule; CD38	Human	HEK293
	The CD38 protein plays a key role in cell signaling, proficiently synthesizing cyclic ADP-ribose (cADPR) as a critical second messenger for glucose-induced insulin secretion. It also promotes the synthesis of the calcium mobilizer niacin-adenine dinucleotide phosphate (NAADP+). CD38 Protein, Human (HEK293, C-His) is the recombinant human-derived CD38 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD38 Protein, Human (HEK293, C-His) is 258 a.a., with molecular weight of 38-50 kDa.

HY-P701631

	TNKS1 Protein, Human (His) TNKS; Poly [ADP-ribose] polymerase tankyrase-1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; Protein poly-ADP-ribosyltransferase tankyrase-1; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I; Tankyrase-1; TANK1	Human	E. coli
	The TNKS1 protein is a polyADP-ribosyltransferase that is integral to multiple cellular processes, including the Wnt signaling pathway, telomere length regulation, and vesicle trafficking. In Wnt signaling, TNKS1 activates this pathway by poly-ADP-ribosylating AXIN1 and AXIN2, promoting their degradation. TNKS1 Protein, Human (His) is the recombinant human-derived TNKS1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of TNKS1 Protein, Human (His) is 235 a.a., .

HY-P701632

	TNKS1 Protein, Human TNKS; Poly [ADP-ribose] polymerase tankyrase-1; ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; Protein poly-ADP-ribosyltransferase tankyrase-1; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I; Tankyrase-1; TANK1	Human	E. coli
	The TNKS1 protein is a polyADP-ribosyltransferase that is integral to multiple cellular processes, including the Wnt signaling pathway, telomere length regulation, and vesicle trafficking. In Wnt signaling, TNKS1 activates this pathway by poly-ADP-ribosylating AXIN1 and AXIN2, promoting their degradation. TNKS1 Protein, Human is the recombinant human-derived TNKS1 protein, expressed by E. coli , with tag free. The total length of TNKS1 Protein, Human is 235 a.a., .

HY-P70022

	CD38 Protein, Human (HEK293, Fc) rHuADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Fc; ADP-ribosyl cyclase 1; cyclic ADP-ribose hydrolase; CD38; T10	Human	HEK293
	The CD38 protein plays a key role in cell signaling, proficiently synthesizing cyclic ADP-ribose (cADPR) as a critical second messenger for glucose-induced insulin secretion. It also promotes the synthesis of the calcium mobilizer niacin-adenine dinucleotide phosphate (NAADP+). CD38 Protein, Human (HEK293, Fc) is the recombinant human-derived CD38 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD38 Protein, Human (HEK293, Fc) is 258 a.a., with molecular weight of 75-90 kDa.

HY-P70044

	CD38 Protein, Mouse (HEK293, Fc) rMuADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Fc; ADP-ribosyl cyclase 1; cyclic ADP-ribose hydrolase; CD38; T10	Mouse	HEK293
	CD38 protein is pivotal in synthesizing crucial second messengers, cyclic ADP-ribose (cADPR) and nicotinate-adenine dinucleotide phosphate (NAADP). cADPR participates in glucose-induced insulin secretion, and NAADP functions as a calcium mobilizer. CD38 also displays cADPR hydrolase activity, showcasing its multifunctionality. CD38 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CD38 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD38 Protein, Mouse (HEK293, Fc) is 260 a.a., with molecular weight of 70-90 kDa.

HY-P70074

	CD38 Protein, Cynomolgus (HEK293, His) rCynADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, His; ADP-ribosyl cyclase 1; cyclic ADP-ribose hydrolase; CD38; T10	Cynomolgus	HEK293
	The CD38 protein plays multifaceted roles in cell signaling and is critical for the synthesis of cyclic ADP-ribose (cADPR) as a possible second messenger in glucose-induced insulin secretion. CD38 also promotes calcium mobilization through the synthesis of niacin adenine dinucleotide phosphate (NAADP+) and exhibits cADPR hydrolase activity. CD38 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD38 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD38 Protein, Cynomolgus (HEK293, His) is 258 a.a., with molecular weight of 38-50 kDa.

HY-P701954

	PARP6 Protein, Human PARP6; Protein mono-ADP-ribosyltransferase PARP6; ADP-ribosyltransferase diphtheria toxin-like 17; ARTD17; Poly [ADP-ribose] polymerase 6; PARP-6	Human	E. coli
	PARP6 protein, a mono-ADP-ribosyltransferase, specializes in mediating the mono-ADP-ribosylation of target proteins. PARP6 Protein, Human is the recombinant human-derived PARP6 protein, expressed by E. coli , with tag free. The total length of PARP6 Protein, Human is 227 a.a., .

HY-P76204

	CD157 Protein, Rat (HEK293, Fc) ADP-ribosyl cyclase; BST1; Cyclic ADP-ribose hydrolase 2; CD157	Rat	HEK293
	CD157 protein catalyzes the synthesis of cADPR from NAD(+) and hydrolyzes cADPR to ADPR. cADPR acts as a second messenger, releasing calcium from intracellular stores. CD157 protein may also contribute to pre-B cell growth. CD157 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD157 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD157 Protein, Rat (HEK293, Fc) is 293 a.a., with molecular weight of ~67 KDa.

HY-P76205

	CD157 Protein, Rat (HEK293, His) ADP-ribosyl cyclase; BST1; Cyclic ADP-ribose hydrolase 2; CD157	Rat	HEK293
	CD157 protein catalyzes the synthesis of cADPR from NAD(+) and hydrolyzes cADPR to ADPR. cADPR acts as a second messenger, releasing calcium from intracellular stores. CD157 protein may also contribute to pre-B cell growth. CD157 Protein, Rat (HEK293, His) is the recombinant rat-derived CD157 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD157 Protein, Rat (HEK293, His) is 293 a.a., with molecular weight of 38-42 KDa.

HY-P70892A

	IL-17RA Protein, Human (CHO, His) ADP-ribosyl cyclase 1; cyclic ADP-ribose hydrolase; CD38; T10	Human	CHO
	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F[1][2]. IL-17RA Protein, Human (CHO, His) is produced in CHO cells with eight C-Terminal His-tags. It consists of 288 amino acids (L33-T320).

HY-P7792

	CD157 Protein, Human (HEK293, Fc) ADP-ribosyl cyclase; ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST1; Cyclic ADP-ribose hydrolase 2; CD157	Human	HEK293
	CD157 Protein, Human (HEK293, Fc) is a recombinant human CD157 expressed in HEK 293 cells with a C-Fc tag at the C-terminus. CD157 Protein is a cell surface receptor and an immunoregulatory molecule.

HY-P701955

	PARP6 Protein, Human (FLAG, GST, Avi) PARP6; Protein mono-ADP-ribosyltransferase PARP6; ADP-ribosyltransferase diphtheria toxin-like 17; ARTD17; Poly [ADP-ribose] polymerase 6; PARP-6	Human	E. coli
	PARP6 protein, a mono-ADP-ribosyltransferase, specializes in mediating the mono-ADP-ribosylation of target proteins. PARP6 Protein, Human (FLAG, GST, Avi) is the recombinant human-derived PARP6 protein, expressed by E. coli , with C-Avi, N-Flag, N-GST labeled tag. The total length of PARP6 Protein, Human (FLAG, GST, Avi) is 227 a.a., .

HY-P7791

	CD157 Protein, Human (HEK293, His) rHuCD157, His; ADP-ribosyl cyclase; ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST1; Cyclic ADP-ribose hydrolase 2; CD157	Human	HEK293
	CD157 Protein, Human (HEK293, His) is a recombinant human CD157 expressed in HEK 293 cells with a His tag at the N-terminus. CD157 Protein is a cell surface receptor and an immunoregulatory molecule.

HY-P7793

	CD157 Protein, Mouse (HEK293, His) rMuCD157, His; ADP-ribosyl cyclase; ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST1; Cyclic ADP-ribose hydrolase 2; CD157	Mouse	HEK293
	CD157 Protein, Mouse (HEK293, His) is a recombinant mouse CD157 expressed in HEK 293 cells with a His tag at the N-terminus. CD157 Protein is a cell surface receptor and an immunoregulatory molecule.

HY-P701951

	PARP14 Protein, Human PARP14; Protein mono-ADP-ribosyltransferase PARP14; ADP-ribosyltransferase diphtheria toxin-like 8; ARTD8; B aggressive lymphoma protein 2; Poly [ADP-ribose] polymerase 14; PARP-14	Human	E. coli
	The PARP14 protein is an ADP-ribosyltransferase that uniquely mono-ADP-ribosylates glutamic acid residues on target proteins such as STAT1 and STAT6, unlike PARP1 and PARP2. It catalyzes STAT1 mono-ADP ribosylation at “Glu-657” and “Glu-705”, reduces STAT1 phosphorylation and inhibits the production of pro-inflammatory cytokines in macrophages following IFNG stimulation. PARP14 Protein, Human is the recombinant human-derived PARP14 protein, expressed by E. coli , with tag free. The total length of PARP14 Protein, Human is 180 a.a., .

HY-P70892

	IL-17RA Protein, Human (288a.a, HEK293, His) ADP-ribosyl cyclase 1; cyclic ADP-ribose hydrolase; CD38; T10	Human	HEK293
	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Human (288a.a, HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 288 amino acids (L33-W320).

HY-P72732

	CD38 Protein, Mouse (HEK293, His) ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADPRC 1; T10; CD38	Mouse	HEK293
	CD38 protein is pivotal in synthesizing crucial second messengers, cyclic ADP-ribose (cADPR) and nicotinate-adenine dinucleotide phosphate (NAADP). cADPR participates in glucose-induced insulin secretion, and NAADP functions as a calcium mobilizer. CD38 also displays cADPR hydrolase activity, showcasing its multifunctionality. CD38 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD38 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD38 Protein, Mouse (HEK293, His) is 260 a.a., with molecular weight of 38-47 kDa.

HY-P701952

	PARP14 Protein, Human (His, Strep) PARP14; Protein mono-ADP-ribosyltransferase PARP14; ADP-ribosyltransferase diphtheria toxin-like 8; ARTD8; B aggressive lymphoma protein 2; Poly [ADP-ribose] polymerase 14; PARP-14	Human	E. coli
	The PARP14 protein is an ADP-ribosyltransferase that uniquely mono-ADP-ribosylates glutamic acid residues on target proteins such as STAT1 and STAT6, unlike PARP1 and PARP2. It catalyzes STAT1 mono-ADP ribosylation at “Glu-657” and “Glu-705”, reduces STAT1 phosphorylation and inhibits the production of pro-inflammatory cytokines in macrophages following IFNG stimulation. PARP14 Protein, Human (His, Strep) is the recombinant human-derived PARP14 protein, expressed by E. coli , with N-Strep, N-8*His labeled tag. The total length of PARP14 Protein, Human (His, Strep) is 180 a.a., .

HY-P701953

	PARP15 Protein, Human (His) PARP15; Protein mono-ADP-ribosyltransferase PARP15; ADP-ribosyltransferase diphtheria toxin-like 7; ARTD7; B-aggressive lymphoma protein 3; Poly [ADP-ribose] polymerase 15; PARP-15	Human	E. coli
	PARP15 protein, acting as a mono-ADP-ribosyltransferase, facilitates the mono-ADP-ribosylation of target proteins. It also functions as a transcriptional negative regulator, impacting cellular processes and gene expression. PARP15 Protein, Human (His) is the recombinant human-derived PARP15 protein, expressed by E. coli , with N-6*His labeled tag. The total length of PARP15 Protein, Human (His) is 176 a.a., .

HY-P72089

	ARF1 Protein, Human (His-GST, Myc) ADP Ribosylation Factor 1; ADP-ribosylation factor 1; ARF 1; ARF1; ARF1_HUMAN	Human	E. coli
	ARF1 is a small GTPase responsible for coordinating protein transport within the Golgi complex. In its GTP-bound state, ARF1 critically regulates Golgi vesicle budding and uncoating by recruiting coat proteins. ARF1 Protein, Human (His-GST, Myc) is the recombinant human-derived ARF1 protein, expressed by E. coli , with N-10*His, C-Myc, GST labeled tag. The total length of ARF1 Protein, Human (His-GST, Myc) is 180 a.a., with molecular weight of ~55 kDa.

HY-P702410

	P2RY12 Protein, Human (Cell-Free, His) P2Y purinoceptor 12; ADP-glucose receptor; ADPG-R; P2T(AC); P2Y(AC); P2Y(cyc); P2Y12 platelet ADP receptor; P2Y(ADP); SP1999	Human	E. coli Cell-free
	P2RY12 Protein, a receptor for adenosine diphosphate (ADP) and adenosine triphosphate (ATP), inhibits the adenylyl cyclase second messenger system via G-proteins. Unlike uridine diphosphate (UDP) and uridine triphosphate (UTP), P2RY12 crucially regulates platelet aggregation and blood coagulation, serving as a key regulator in these physiological processes. P2RY12 Protein, Human (Cell-Free, His) is the recombinant human-derived P2RY12 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of P2RY12 Protein, Human (Cell-Free, His) is 342 a.a., with molecular weight of 42.2 kDa.

HY-P75502

ARF5 Protein, Human (His)

ADP-ribosylation factor 5; ARF5
Human E. coli

HY-P75583

	ARF3 Protein, Human (His) ADP-ribosylation factor 3; ARF3	Human	E. coli
	ARF3 protein, a GTP-binding allosteric activator of cholera toxin, plays a role in protein trafficking and vesicle dynamics in the Golgi apparatus. Beyond toxin activation, ARF3 interacts with PRKCABP, participating in diverse cellular processes. It also associates with PI4KB and NCS1/FREQ at the Golgi complex, emphasizing its role in crucial molecular interactions for cellular functions. ARF3 Protein, Human (His) is the recombinant human-derived ARF3 protein, expressed by E. coli , with N-His labeled tag. The total length of ARF3 Protein, Human (His) is 181 a.a., with molecular weight of ~23 kDa.

HY-P702020

	SLC25A5 Protein, Human (Sf9, His, MBP, FLAG) SLC25A5; ADP/ATP translocase 2; ADP; ATP carrier protein 2; ADP; ATP carrier protein; fibroblast isoform; Adenine nucleotide translocator 2; ANT 2; Solute carrier family 25 member 5	Human	Sf9 insect cells
	The SLC25A5 protein is an ADP:ATP antiporter on the inner mitochondrial membrane that imports ADP for ATP synthesis and exports ATP for cellular processes. It operates via an alternating access mechanism, cycling between a cytoplasmic open state and a stromal open state. SLC25A5 Protein, Human (Sf9, His, MBP, FLAG) is the recombinant human-derived SLC25A5 protein, expressed by Sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag. The total length of SLC25A5 Protein, Human (Sf9, His, MBP, FLAG) is 297 a.a., .

HY-P7462

	ADPRH/ARH1 Protein, Human (His) rHuADP-ribosylarginine hydrolase, His; ADPRH; ARH-1; ADP-ribosylarginine hydrolase	Human	E. coli
	ADPRH/ARH1 Protein, Human (His) is human recombinant ADP-ribosylarginine hydrolase (ADPRH) with a N-terminal His-tag. ADPRH/ARH1 Protein, Human (His) is expressed in E. coli.

HY-P71660

	ARL2BP Protein, Human (GST) ADP ribosylation factor like 2 binding protein; ADP-ribosylation factor-like protein 2-binding protein; ARL2BP protein; BART; BART1; Binder of ARF2 protein 1	Human	E. coli
	The ARL2BP protein cooperates with ARL2 to play a crucial role in the nuclear translocation, retention, and transcriptional activity of STAT3, highlighting its cellular involvement. As a potential effector of ARL2, ARL2BP forms a complex with ARL2, SLC25A6, and ARL3. ARL2BP Protein, Human (GST) is the recombinant human-derived ARL2BP protein, expressed by E. coli , with N-GST labeled tag. The total length of ARL2BP Protein, Human (GST) is 163 a.a., with molecular weight of ~45.8 kDa.

HY-P76525

	NUDT5 Protein, Human (His) ADP-sugar pyrophosphatase; Nudix motif 5; hNUDT5; YSA1H; NUDIX5	Human	E. coli
	The NUDT5 protein acts as an ADP-glycopyrophosphatase or synthesizes ATP. NUDT5 Protein, Human (His) is the recombinant human-derived NUDT5 protein, expressed by E. coli , with N-His labeled tag. The total length of NUDT5 Protein, Human (His) is 218 a.a., with molecular weight of 30-35 KDa.

HY-P702409

	P2RY1 Protein, Mouse (Cell-Free, His) P2Y purinoceptor 1; ADP receptor; Purinergic receptor	Mouse	E. coli Cell-free
	The P2RY1 Protein serves as a receptor for extracellular adenine nucleotides, particularly ADP. In platelets, ADP binding to P2RY1 triggers intracellular calcium mobilization through phospholipase C activation, inducing platelet shape changes and culminating in platelet aggregation. P2RY1 Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived P2RY1 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of P2RY1 Protein, Mouse (Cell-Free, His) is 373 a.a., with molecular weight of 48.3 kDa.

HY-P75955

	PARP3 Protein, Human (sf9, His-GST) Protein mono-ADP-ribosyltransferase PARP3; ARTD3; IRT1; ADPRT-3; PARP-3	Human	Sf9 insect cells
	The PARP3 protein is a mono-ADP ribosyltransferase that responds to DNA damage, focusing on mono-ADP ribosylation of proteins such as histone H2B, XRCC5, and XRCC6. PARP3 plays a key role in the DNA repair process, participating in precise nonhomologous end joining and inhibiting G-quadruplex structure. PARP3 Protein, Human (sf9, His-GST) is the recombinant human-derived PARP3 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of PARP3 Protein, Human (sf9, His-GST) is 533 a.a., with molecular weight of ~95 kDa.

HY-P76730

ARL6IP6 Protein, Human (HEK293, Fc)

ADP-ribosylation factor-like protein 6-interacting protein 6; Aip-6; PFAAP1
Human HEK293

HY-P76156

	ARL2BP Protein, Human (His) ADP ribosylation factor like 2 binding protein; BART; BART1; Binder of ARF2 protein 1	Human	E. coli
	The ARL2BP protein cooperates with ARL2 to play a crucial role in the nuclear translocation, retention, and transcriptional activity of STAT3, highlighting its cellular involvement. As a potential effector of ARL2, ARL2BP forms a complex with ARL2, SLC25A6, and ARL3. ARL2BP Protein, Human (His) is the recombinant human-derived ARL2BP protein, expressed by E. coli , with N-6*His labeled tag. The total length of ARL2BP Protein, Human (His) is 163 a.a., with molecular weight of ~21 KDa.

HY-P701629

	P2Y1 Protein, Human (Sf9, FLAG) P2RY1; P2Y purinoceptor 1; P2Y1; ADP receptor; Purinergic receptor	Human	Sf9 insect cells
	The P2Y1 protein acts as a receptor for extracellular adenine nucleotides, specifically ADP. In platelets, ADP binding activates phospholipase C, leading to intracellular calcium mobilization, platelet shape changes, and aggregation. P2Y1 Protein, Human (Sf9, FLAG) is the recombinant human-derived P2Y1 protein, expressed by Sf9 insect cells , with N-Flag labeled tag. The total length of P2Y1 Protein, Human (Sf9, FLAG) is 372 a.a., .

HY-P701630

	P2Y1 Protein, Human (Sf9, FLAG, His) P2RY1; P2Y purinoceptor 1; P2Y1; ADP receptor; Purinergic receptor	Human	Sf9 insect cells
	The P2Y1 protein acts as a receptor for extracellular adenine nucleotides, specifically ADP. In platelets, ADP binding activates phospholipase C, leading to intracellular calcium mobilization, platelet shape changes, and aggregation. P2Y1 Protein, Human (Sf9, FLAG, His) is the recombinant human-derived P2Y1 protein, expressed by Sf9 insect cells , with C-10*His, N-Flag labeled tag. The total length of P2Y1 Protein, Human (Sf9, FLAG, His) is 372 a.a., .

HY-P77297

	ART4/CD297 Protein, Cynomolgus (HEK293, Fc) Ecto-ADP-ribosyltransferase 4; ARTC4; Mono(ADP-ribosyl)transferase 4; DO; DOK1	Cynomolgus	HEK293
	ART4/CD297 Protein belongs to the Arg-specific ADP-ribosyltransferase family. ART4/CD297 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived ART4/CD297 protein, expressed by HEK293, with C-hFc labeled tag. The total length of ART4/CD297 Protein, Cynomolgus (HEK293, Fc) is 270 a.a., with molecular weight of ~66 kDa.

HY-P77298

	ART4/CD297 Protein, Cynomolgus (HEK293, His) Ecto-ADP-ribosyltransferase 4; ARTC4; Mono(ADP-ribosyl)transferase 4; DO; DOK1	Cynomolgus	HEK293
	ART4/CD297 Protein belongs to the Arg-specific ADP-ribosyltransferase family. ART4/CD297 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived ART4/CD297 protein, expressed by HEK293, with C-His labeled tag. The total length of ART4/CD297 Protein, Cynomolgus (HEK293, His) is 270 a.a., with molecular weight of 41-46 kDa.

HY-P77299

ART4/CD297 Protein, Mouse (HEK293, Fc)

Ecto-ADP-ribosyltransferase 4; ARTC4; Mono(ADP-ribosyl)transferase 4; DO; DOK1
Mouse HEK293
HY-P77300

ART4/CD297 Protein, Mouse (HEK293, His)

Ecto-ADP-ribosyltransferase 4; ARTC4; Mono(ADP-ribosyl)transferase 4; DO; DOK1
Mouse HEK293

HY-P77301

	ART4/CD297 Protein, Rat (HEK293, His) Ecto-ADP-ribosyltransferase 4; ARTC4; Mono(ADP-ribosyl)transferase 4; DO; DOK1	Rat	HEK293
	ART4/CD297 is a predicted NAD+ ADP-ribosyltransferase that exhibits biased expression in tissues such as the adrenal gland and thymus. As an ortholog of human ART4, it is involved in peptidyl arginine ADP ribosylation. ART4/CD297 Protein, Rat (HEK293, His) is the recombinant rat-derived ART4/CD297 protein, expressed by HEK293 , with C-His labeled tag. The total length of ART4/CD297 Protein, Rat (HEK293, His) is 269 a.a., with molecular weight of 36-41 kDa.

HY-P76734

	ART1 Protein, Cynomolgus (HEK293, His) NAD(P)(+)--arginine ADP-ribosyltransferase; Mono(ADP-ribosyl)transferase	Cynomolgus	HEK293
	ART1 Protein is an arginine-specific ADP-ribosyltransferase. ART1 is involved in the regulation of a diverse array of pathophysiological processes, including proliferation, invasion, apoptosis, autophagy and angiogenesis of colorectal cancer (CRC) cells. ART1 plays a crucial role in the elevation of glucose consumption in CT26 cells and may regulate GLUT1-dependent glycolysis in CRC via the PI3K/AKT/HIF1α pathway. ART1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived ART1 protein, expressed by HEK293 , with C-His labeled tag. The total length of ART1 Protein, Cynomolgus (HEK293, His) is 272 a.a., with molecular weight of 33-43 KDa.

HY-P74409

	ART3 Protein, Human (HEK293, His) Ecto-ADP-ribosyltransferase 3; ARTC3; ART3; TMART	Human	HEK293
	ART3 is a member of the mono-ADP-ribosyltransferase family genes which is involved in cell division, DNA-repair and the regulation of the inflammatory response. The temporary and restricted expression of ART3 in spermatocytes might be linked to cell division processes underlying the formation of spermatocytes and the regulation of spermatogenesis. Moreover, it induces TNBC cell growth and invasion by activating Akt and ERK. ART3 Protein, Human (HEK293, His) is the recombinant human-derived ART3 protein, expressed by HEK293 , with C-His labeled tag. The total length of ART3 Protein, Human (HEK293, His) is 362 a.a., with molecular weight of ~49 kDa.

HY-P70077

	CD38 Protein, Rat (HEK293, His) rRtADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, His ; 17-1A; 323/A3; ACSTD1; CD326; EGP-2; EGP314; EGP40; EpCAM; MOC31; TACST-1; TACSTD1; TROP1;	Rat	HEK293
	CD38 protein plays diverse roles, synthesizing key second messengers: cyclic ADP-ribose (cADPR) for glucose-induced insulin secretion and nicotinate-adenine dinucleotide phosphate (NAADP) as a calcium mobilizer. Its cADPR hydrolase activity adds to its versatility. Notably, CD38 also regulates osteoclastic bone resorption, likely by producing cADPR and initiating a calcium ion signal through ryanodine receptor activation. CD38 Protein, Rat (HEK293, His) is the recombinant rat-derived CD38 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD38 Protein, Rat (HEK293, His) is 259 a.a., with molecular weight of 35-50 kDa.

HY-P71658

	OARD1 Protein, Human (Myc, His) C6orf130; CF130_HUMAN; Chromosome 6 open reading frame 130; dJ34B21.3; O acetyl ADP ribose deacetylase C6orf130; Uncharacterized protein C6orf130	Human	E. coli
	OARD1 is an ADP:ATP antiporter that regulates mitochondrial energy dynamics by shuttling ADP for ATP synthesis and exporting ATP. It induces mitochondrial thermogenesis, uncouples proton flux and regulates ATP production efficiency. OARD1 Protein, Human (Myc, His) is the recombinant human-derived OARD1 protein, expressed by E. coli , with N-His, C-Myc labeled tag. The total length of OARD1 Protein, Human (Myc, His) is 151 a.a., with molecular weight of ~24.3 kDa.

Cat. No.	Product Name	Chemical Structure

HY-Z0283S

Benzamide-15N

Benzamide- ¹⁵N is a ¹⁵N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP)[1][2].

HY-W010918S

Adenosine 5'-diphosphate-d13 dilithium

Adenosine 5'-diphosphate-d₁₃ (Adenosine diphosphate-d₁₃ dilithium; ADP-d₁₃) dilithium is deuterium labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-W010918S1

Adenosine 5'-diphosphate-13C10 dilithium

Adenosine 5'-diphosphate- ¹³C₁₀ (Adenosine diphosphate- ¹³C₁₀ dilithium; ADP- ¹³C₁₀) dilithium is ¹³C-labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-W010918S2

Adenosine 5'-diphosphate-15N5 dilithium

Adenosine 5'-diphosphate- ¹⁵N₅ (Adenosine diphosphate- ¹⁵N₅ dilithium; ADP- ¹⁵N₅) dilithium is ¹⁵N labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-B0153AS

Ticlopidine-d4 hydrochloride
Ticlopidine-d₄ (hydrochloride) is the deuterium labeled Ticlopidine hydrochloride. Ticlopidine hydrochloride is an adenosine diphosphate (ADP) receptor inhibitor against platelet aggregation with IC50 of ~2 μM.

HY-15284S1

Prasugrel-d3
Prasugrel-d₃ is the deuterium labeled Prasugrel. Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[1].

HY-15284S

Prasugrel-d5
Prasugrel-d₅ is deuterium labeled Prasugrel. Prasugrel (PCR 4099), a thienopyridine and prodrug, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[1].

HY-15284S2

Prasugrel-d4
Prasugrel-d₄ is the deuterium labeled Prasugrel[1]. Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[2].

HY-113432S

Nudifloramide-d3
Nudifloramide-d₃ (2PY-d3) is the deuterium labeled Nudifloramide. Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro[1].

HY-113371S

2-Methylcitric acid-d3

2-Methylcitric acid-d₃ is the deuterium labeled 2-Methylcitric acid. 2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate[1].

HY-136406S

Bongkrekic acid-13C28
Bongkrekic acid-13C28 is the C13 labeled Bongkrekic acid. Bongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans. Bongkrekic acid specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the electron transport chain. Bongkrekic acid has to cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport .

HY-17459S

Clopidogrel-d3 hydrogen sulfate

Clopidogrel-d₃ (hydrogen sulfate) is the deuterium labeled Clopidogrel hydrogen sulfate[1]. Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively. Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation．Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor[2][3][4][5][6].

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