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Results for "

AEG

" in MedChemExpress (MCE) Product Catalog:

18

Inhibitors & Agonists

12

Peptides

3

Recombinant Proteins

8

Antibodies

2

Click Chemistry

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-107599
    AEG3482

    		JNK Apoptosis Neurological Disease
    AEG3482 is a potent antiapoptotic compound that inhibits Jun kinase (JNK) activity through induced expression of heat shock protein 70 (HSP70). AEG3482 directly binds HSP90, thereby facilitating HSF1-dependent expression of HSP70 and HSP25 .
    AEG3482
  • HY-RS26269
    Crisp3 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Crisp3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Crisp3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Crisp3 Rat Pre-designed siRNA Set A
    Crisp3 Rat Pre-designed siRNA Set A
  • HY-120434
    AEG40826

    HGS1029

    		 IAP Cancer
    AEG40826 (HGS1029), a second mitochondria-derived activator of caspases (SMAC) mimetic, is an inhibitor of apoptosis (IAP) inhibitor. AEG40826 degrades cellular IAP1 (cIAP1) and blocks TNF-α pro-survival signaling. AEG40826 can be used for cancer research .
    AEG40826
  • HY-151738
    Fmoc-Aeg(N3)-OH

    		ADC Linker Others
    Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis . Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Fmoc-Aeg(N3)-OH
  • HY-151828
    N3-Gly-Aeg(Fmoc)-OH

    		ADC Linker Others
    N3-Gly-Aeg(Fmoc)-OH is a click chemistry reagent containing an azide group. PNA building-block that can be further modified using Click-chemistry . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    N3-Gly-Aeg(Fmoc)-OH
  • HY-W131404
    Boc-Aeg-OEt

    		Biochemical Assay Reagents Others
    Boc-Aeg-OEt is an aminoethylglycine monomer based on a Boc- and ethyl ester-protected AEG backbone, with substitution by a pyridine ligand. Boc-Aeg-OEt reduces steric hindrance in a series of dipeptide synthesis reactions, and has higher solubility in common solvents than the Fmoc-aeg-OtBu backbone .
    Boc-Aeg-OEt
  • HY-107599R
    AEG3482 (Standard)

    		Reference Standards JNK Apoptosis Neurological Disease
    AEG3482 (Standard) is the analytical standard of AEG3482 (HY-107599). This product is intended for research and analytical applications. AEG3482 is a potent antiapoptotic compound that inhibits Jun Kinase (JNK) activity through induced expression of heat shock protein 70 (HSP70). AEG3482 directly binds HSP90, thereby facilitating HSF1-dependent expression of HSP70 and HSP25 .
    AEG3482 (Standard)
  • HY-P11690
    Fmoc-Aeg-OBn

    		Biochemical Assay Reagents Cancer
    Fmoc-Aeg-OBn is a benzyl-protected N-(2-aminoethyl)-glycine PNA backbone derivative. Fmoc-Aeg-OBn serves as a key intermediate for the synthesis of Fmoc-protected PNA monomers with modified nucleobases. Fmoc-Aeg-OBn can be used to prepare PNA with unique physicochemical properties, which is suitable for antisense and gene diagnostic applications. Fmoc-Aeg-OBn is applicable to cancer-related research .
    Fmoc-Aeg-OBn
  • HY-P11695
    Fmoc-Aeg(Dde)

    		Biochemical Assay Reagents Others
    Fmoc-Aeg (Dde) is a protected aminoethylglycine (AEG) monomer used for solid-phase synthesis of peptide nucleic acids (PNAs). Fmoc-Aeg (Dde) contains the fluorenylmethoxycarbonyl (Fmoc) and 1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene) ethyl (Dde) protecting groups .
    Fmoc-Aeg(Dde)
  • HY-W574398
    Fmoc-Aeg-OH

    		Biochemical Assay Reagents Others
    Fmoc-Aeg-OH is a peptide nucleic acid (PNA) backbone intermediate and an Fmoc-protected carboxylic acid. Fmoc-Aeg-OH can be coupled with base acetic acids to synthesize Fmoc-protected PNA monomers, including those with modified bases .
    Fmoc-Aeg-OH
  • HY-P11694
    Alloc-Aeg(Fmoc)-OH

    		Biochemical Assay Reagents Neurological Disease
    Alloc-Aeg (Fmoc)-OH is a protected serine triphosphate building block and an Nα-Fmoc protected amino acid. Alloc-Aeg (Fmoc)-OH contains serine protected by α-N-allyloxycarbonyl (Alloc) and bis (allyl) phosphate groups, and it can be used in the synthesis of peptide nucleic acids (PNAs). Alloc-Aeg (Fmoc)-OH is applicable to research related to Alzheimer's disease .
    Alloc-Aeg(Fmoc)-OH
  • HY-W871908
    Boc-Aeg(Fmoc)-OH

    		Biochemical Assay Reagents Others
    Boc-Aeg(Fmoc)-OH is a Boc/Fmoc-protected 2-aminoethylglycine building block. Boc-Aeg(Fmoc)-OH facilitates solid-phase synthesis of acridine oligomers with a (2-aminoethyl)glycine backbone .
    Boc-Aeg(Fmoc)-OH
  • HY-P11693
    Fmoc-Aeg-OMe hydrochloride

    		Drug Intermediate Others
    Fmoc-Aeg-OMe hydrochloride is a methyl ester derivative of Fmoc-protected aminoethylglycine and can be used fo polyamide nucleic acid synthesis .
    Fmoc-Aeg-OMe hydrochloride
  • HY-W424255
    Fmoc-Aeg-OMe

    		Drug Intermediate Others
    Fmoc-Aeg-OMe is a methyl ester derivative of Fmoc-protected aminoethylglycine and can be used fo polyamide nucleic acid synthesis .
    Fmoc-Aeg-OMe
  • HY-P11692
    Fmoc-Aeg-OtBu

    		Drug Intermediate Others
    Fmoc-Aeg-OtBu is an intermediate in solid-phase peptide synthesis, and serves as a building block for introducing pseudoproline motifs or backbone modifications .
    Fmoc-Aeg-OtBu
  • HY-W415169
    H-Aeg(Fmoc)-OBzl hydrochloride

    		Drug Intermediate Others
    H-Aeg(Fmoc)-OBzl hydrochloride is an Fmoc-protected aminoethylglycine derivative with benzyl ester and can be used for synthesis of peptide nucleic acid and protected oligomers.
    H-Aeg(Fmoc)-OBzl hydrochloride
  • HY-P11696
    H-Aeg(Fmoc)-OH hydrochloride

    		Drug Intermediate Others
    H-Aeg(Fmoc)-OH hydrochloride is an Fmoc-protected aminoethylglycine monomer with a free carboxyl group and can be used for peptide nucleic acid synthesis.
    H-Aeg(Fmoc)-OH hydrochloride
  • HY-W402665
    Fmoc-PNA-T-OH

    Fmoc-C(Bhoc)-AEG-OH

    		 Drug Intermediate Metabolic Disease
    Fmoc-PNA-T-OH (Fmoc-C (Bhoc)-Aeg-OH) is a Bhoc-protected peptide nucleic acid (PNA) monomer. Fmoc-PNA-T-OH is used in the research of type 2 diabetes (t2d) .
    Fmoc-PNA-T-OH

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