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Results for "

AG-3-5

" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-11062
    Icilin

    AG-3-5

    		 TRP Channel Inflammation/Immunology Neurological Disease
    Icilin (AG-3-5) is a super-agonist of the transient receptor potential M8 (TRPM8) ion channel. Icilin activates TRPM8 in EGTA in a dose-dependent manner (EC50=1.4 μM). Icilin is a “super-cooling agent”. Icilin attenuates autoimmune neuroinflammation through modulation of the T-cell response.