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ALK

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  • HY-P72454
    TGFBR1/ALK-5 Protein, Mouse (HEK293, Fc)

    TGF-beta receptor type-1; ALK-5; SKR4; TbetaR-I; AAT5

    		 Mouse HEK293
    TGFBR1 is a transmembrane kinase that cooperates with TGFBR2 to form the TGF-β receptor complex. This complex is activated by cytokines and regulates a variety of processes, including cell cycle arrest, mesenchymal cell control, wound healing, and carcinogenesis. TGFBR1/ALK-5 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived TGFBR1/ALK-5 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TGFBR1/ALK-5 Protein, Mouse (HEK293, Fc) is 96 a.a., with molecular weight of 40-60 kDa.
  • HY-P7481
    ACVRL1/ALK1 Protein, Mouse (HEK293, Fc)

    rMuActivin Receptor-like Kinase 1, C-Fc; ALK-1; ACVRL1; Activin Receptor-like Kinase 1

    		 Mouse HEK293
    ALK-1, also known as ACVRL1, is a type I receptor for TGF-β superfamily with 2 ligands, BMP9 and BMP10. ALK-1 is predominantly expressed in endothelial cells and plays a critical role in regulating developmental and pathological angiogenesis. ACVRL1/ALK1 Protein, Mouse (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 97 amino acids (D23-P119).
  • HY-P7483
    BMPR1A/ALK-3 Protein, Mouse (129a.a, HEK293, His-Fc)

    Bone morphogenetic protein receptor type-1A; ALK-3; SKR5; CD292; ACVRLK3; BMPR-IA

    		 Mouse HEK293
    BMPR1A/ALK-3 protein (ACVRLK3) is the receptor bone morphogenetic protein (BMP) type I receptors, widely expressed in tissues. BMPR1A/ALK-3 protein mediates iron metabolism factor hepcidin expression, interacts with GDF5/6 to regulate chondrocyte differentiation and adipogenesis. BMPR1A-ID2/ZEB1-TGFBR2 signaling axis could serve as a potentia target for pulmonary arterial hypertension (PAH) and other endothelial-mesenchymal transition (EndoMT)-related vascular disorders. Mouse BMPR1A/ALK-3 has a full length of 532 a.a., with a motif (107-109 a.a.) mediating specificity for BMP ligand. BMPR1A/ALK-3 Protein, Mouse (129a.a, HEK293, His-Fc) is produced in HEK293 cells and has 129 amino acids (Q24-R152), with C-terminal Fc- and His-tags.
  • HY-P7486
    Activin RIB/ALK-4 Protein, Mouse (HEK293, Fc)

    rMuActivin Receptor IB, C-Fc; ALK-4; Activin RIB; ACVR1B

    		 Mouse HEK293
    Activin RIB, also known as activin receptor type-1B (ACVR1B) or ALK-4, is a type I transmembrane serine/threonine kinase receptor that is part of the TGF-β receptor superfamily. Activin binds to a type II activin receptor (ACVR2or ACVR2B) and then recruits ACVR1B. Activin RIB/ALK-4 Protein, Mouse (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 95 amino acids (L32-E126).
  • HY-P72819
    ACVRL1/ALK1 Protein, Mouse (HEK293, His-Fc)

    Serine/threonine-protein kinase receptor R3; SKR3; ALK-1; TSR-I; ACVRL1

    		 Mouse HEK293
    ALK-1, also known as ACVRL1, is a type I receptor for TGF-β superfamily with 2 ligands, BMP9 and BMP10. ALK-1 is predominantly expressed in endothelial cells and plays a critical role in regulating developmental and pathological angiogenesis. ACVRL1/ALK1 Protein, Mouse (HEK293, His-Fc) is produced in HEK293 cells with a C-Terminal His-tag and a C-Terminal Fc-tag. It consists of 119 amino acids (M1-P119).
  • HY-P76902
    ENPP-7 Protein, Mouse (HEK293, His)

    Ectonucleotide pyrophosphatase/phosphodiesterase family member 7; NPP-7; ALK-Smase

    		 Mouse HEK293
    The ENPP-7 protein acts as a choline-specific phosphodiesterase and is essential for sphingomyelin digestion, ceramide formation, and FA absorption in the gastrointestinal tract. It hydrolyzes sphingomyelin to release ceramide and phosphocholine. ENPP-7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ENPP-7 protein, expressed by HEK293 , with C-His labeled tag. The total length of ENPP-7 Protein, Mouse (HEK293, His) is 400 a.a., with molecular weight of ~60 kDa.
  • HY-P78041
    SLPI Protein, Mouse (HEK293, Fc)

    ALP; BLPI; HUSI-1; MPI; WAP4; WFDC4; ALK1; HUSI; SLPI

    		 Mouse HEK293
    SLPI Protein, an acid-stable proteinase inhibitor, modulates immune responses to bacterial infection. It down-regulates responses to bacterial lipopolysaccharide (LPS) and regulates NF-kappa-B activation and inflammatory responses. SLPI Protein also has antimicrobial activity against mycobacteria and contributes to resistance against M.tuberculosis and L.major. It is involved in wound healing by limiting protease activity and interacts with GRN to protect progranulin from proteolysis. SLPI Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived SLPI protein, expressed by HEK293, with C-hFc labeled tag. The total length of SLPI Protein, Mouse (HEK293, Fc) is 106 a.a., with molecular weight of 40-50 kDa.
  • HY-P76176
    BMPRIB/ALK-6 Protein, Mouse (HEK293, Fc)

    Bone morphogenetic protein receptor type-1B; BMPR-1B; CDw293

    		 Mouse HEK293
    BMPR1B/ALK-6 protein is a type I member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. BMPR1B/ALK-6 is the receptor for BMP-7/OP-1 and GDF-5, positively regulates chondrocyte differentiation through GDF-5 interaction. BMPR1B/ALK-6 also involves in SCUBE3/BMP-2/BMP-4 signals regulation, controlling growth, morphogenesis, and bone and teeth development. ALK-6/GDF-9/BMP-15 signals is essential in prolificacy of goat. The mouse BMPR1B/ALK-6 protein contains 502 amino acids and a transmembrane domain (127-148 a.a.). BMPRIB/ALK-6 Protein, Mouse (HEK293, Fc) is produced by HEK293 cells (K14-K126) with C-terminal hFc-tag.

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