APOA1 Inhibitors

By Targets:	Biochemical Assay Reagents (1) Small Interfering RNA (siRNA) (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-124187

Pinolenic acid ethyl ester Ethyl pinolenate	Biochemical Assay Reagents	Others
Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.

HY-RS00829

APOA1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
APOA1 Human Pre-designed siRNA Set A contains three designed siRNAs for APOA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

APOA1 Human Pre-designed siRNA Set A APOA1 Human Pre-designed siRNA Set A

Cat. No.	Product Name	Type

HY-124187

Pinolenic acid ethyl ester Ethyl pinolenate	Biochemical Assay Reagents
Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.

Pinolenic acid ethyl ester

Ethyl pinolenate

Biochemical Assay Reagents

Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.

Species:	Human (4) Mouse (4)
Tag:	His (3) Tag Free (1) Fc (3)
Source:	HEK293 (7) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P7526

	*Apolipoprotein A-I/APOA1* Protein, Human** rHuApolipoprotein A-I; APOA1; Apolipoprotein A-I	Human	E. coli
	Apolipoprotein A-I Protein, Human expresses in E. coli. Apolipoprotein A-I (ApoA-I), the major protein component in high-density lipoprotein (HDL), plays key roles in the Reverse Cholesterol Transport pathway. Apolipoprotein A-I is associated with dengue virus (DV) particles and enhances virus infection through SR-BI.

HY-P7525

	*Apolipoprotein A-I/APOA1* Protein, Human (HEK293, His)** 1 Publications Verification rHuApolipoprotein A-I, His; APOA1; Apolipoprotein A-I	Human	HEK293
	Apolipoprotein A-I Protein, Human (HEK293, His) expresses in HEK293 with a His tag at the N-terminus. Apolipoprotein A-I (ApoA-I), the major protein component in high-density lipoprotein (HDL), plays key roles in the Reverse Cholesterol Transport pathway. Apolipoprotein A-I is associated with dengue virus (DV) particles and enhances virus infection through SR-BI.

HY-P72832

	*Apolipoprotein A-I/APOA1* Protein, Human (HEK293, Fc)** Apolipoprotein A-I; Apo-AI; ProAPOA-I; APOA1	Human	HEK293
	Apolipoprotein AI plays a key role in reverse cholesterol transport, promoting cholesterol efflux from tissues and acting as a cofactor for lecithin cholesterol acyltransferase (LCAT). It forms homodimers and participates in the SPAP complex, which is essential for sperm motility, interacting with both NAXE and CLU. Apolipoprotein A-I/APOA1 Protein, Human (HEK293, Fc) is the recombinant human-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Apolipoprotein A-I/APOA1 Protein, Human (HEK293, Fc) is 243 a.a., with molecular weight of 55-65 kDa.

HY-P78238

	*Apolipoprotein A-I/APOA1* Protein, Mouse (240a.a, HEK293, Fc)** Apo-AI; ProAPOA-I; APOA1; Apolipoprotein A-I; APOA1; MGC117399; Alp-1; Brp-14; Ltw-1; Lvtw-1; Sep-1; Sep-2	Mouse	HEK293
	Apolipoprotein A-I (APOA1) Protein, pivotal in cholesterol reverse transport, facilitates efflux from tissues and acts as a crucial cofactor for lecithin cholesterol acyltransferase (LCAT), promoting cholesterol excretion. As a homodimer, APOA1 is integral to the sperm activating protein complex (SPAP), interacting with APOA1BP, CLU, NDRG1, SCGB3A2, NAXE, and YJEFN3, demonstrating diverse molecular associations. Its involvement extends beyond cholesterol metabolism to influence cellular processes like spermatozoa motility and protein interactions. Apolipoprotein A-I/APOA1 Protein, Mouse (240a.a, HEK293, Fc) is the recombinant mouse-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293, with C-hFc labeled tag. The total length of Apolipoprotein A-I/APOA1 Protein, Mouse (240a.a, HEK293, Fc) is 240 a.a., with molecular weight of 55-65 kDa.

HY-P72833

	*Apolipoprotein A-I/APOA1* Protein, Mouse (246a.a, HEK293, Fc)** Apolipoprotein A-I; Apo-AI; ProAPOA-I; APOA1	Mouse	HEK293
	The apolipoprotein AI (APOA1) protein is key to reverse cholesterol transport, promoting tissue efflux, and serves as an important cofactor for lecithin cholesterol acyltransferase (LCAT), promoting cholesterol excretion. As a homodimer, APOA1 is a component of the sperm activating protein complex (SPAP), interacts with APOA1BP, CLU, NDRG1, SCGB3A2, NAXE and YJEFN3, exhibiting multiple molecular associations. Apolipoprotein A-I/APOA1 Protein, Mouse (246a.a, HEK293, Fc) is the recombinant mouse-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Apolipoprotein A-I/APOA1 Protein, Mouse (246a.a, HEK293, Fc) is 246 a.a., with molecular weight of ~58 kDa.

HY-P75503A

	*Apolipoprotein A-I/APOA1* Protein, Mouse(HEK293, C-His)**	Mouse	HEK293
	The apolipoprotein AI (APOA1) protein is key to reverse cholesterol transport, promoting tissue efflux, and serves as an important cofactor for lecithin cholesterol acyltransferase (LCAT), promoting cholesterol excretion. As a homodimer, APOA1 is a component of the sperm activating protein complex (SPAP), interacts with APOA1BP, CLU, NDRG1, SCGB3A2, NAXE and YJEFN3, exhibiting multiple molecular associations. Apolipoprotein A-I/APOA1 Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Apolipoprotein A-I/APOA1 Protein, Mouse (HEK293, C-His) is 246 a.a., with molecular weight of ~26-28 kDa.

HY-P75503

	*Apolipoprotein A-I/APOA1* Protein, Mouse (HEK293, His)** Apolipoprotein L1; Apo-L; ApoL-I; APOL1; APOL	Mouse	HEK293
	The apolipoprotein AI (APOA1) protein is key to reverse cholesterol transport, promoting tissue efflux, and serves as an important cofactor for lecithin cholesterol acyltransferase (LCAT), promoting cholesterol excretion. As a homodimer, APOA1 is a component of the sperm activating protein complex (SPAP), interacts with APOA1BP, CLU, NDRG1, SCGB3A2, NAXE and YJEFN3, exhibiting multiple molecular associations. Apolipoprotein A-I/APOA1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Apolipoprotein A-I/APOA1 Protein, Mouse (HEK293, His) is 246 a.a., with molecular weight of 27-31 kDa.

HY-P76155

	APOA1BP Protein, Human (HEK293, His) NAD(P)H-hydrate epimerase; Apolipoprotein A-I-binding protein; AI-BP; YJEFN1; NAXE; AIBP	Human	HEK293
	APOA1BP protein plays a crucial role in cellular processes by catalyzing the S- and R-type epimerization of NAD(P)HX, a protein that results from enzymatic or heat-dependent hydration. Damaged form of NAD(P)H. This catalytic activity is a prerequisite for the subsequent action of S-specific NAD(P)H hydrate dehydratase, enabling the repair of both epimers of NAD(P)HX. APOA1BP Protein, Human (HEK293, His) is the recombinant human-derived APOA1BP protein, expressed by HEK293 , with C-His labeled tag. The total length of APOA1BP Protein, Human (HEK293, His) is 288 a.a., with molecular weight of ~30.6 KDa.


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Cat. No.	Product Name	Application	Reactivity

HY-P81137

APOA1 Antibody Apo-AI; APOA I; APOA-I; APOA1_HUMAN; Apolipoprotein A-I(1-242); Apolipoprotein A1; Apolipoprotein A 1; Apolipoprotein AI; Apolipoprotein A I; Brp14; Ltw1; Lvtw1; Sep1; Sep2.	WB; ELISA; IHC-P; IHC-F; Flow-Cyt; IF	Human, Mouse, Rat, Chicken(predicted: Pig, Cow)
APOA1 Antibody is an unconjugated, approximately 28 kDa, rabbit-derived, anti-APOA1 polyclonal antibody. APOA1 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, chicken, and predicted: pig, cow background without labeling.

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