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Results for "

AST

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

1

Peptides

3

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P3016
    Aspartate aminotransferase, Genetically engineered bacteria

    EC 2.6.1.1; GOT; AST

    		 Endogenous Metabolite Others
    Aspartate aminotransferase, Genetically engineered bacteria (EC 2.6.1.1) (AST) is a transaminase enzyme, is often used in biochemical studies. Aspartate aminotransferase catalyzes aspartate and alpha-ketoglutarate converts to oxaloacetate and glutamate. Aspartate aminotransferase can be found in cerebrospinal fluid, exudates, and transudates .
    Aspartate aminotransferase, Genetically engineered bacteria
  • HY-138627A
    AST5902 trimesylate

    		EGFR Drug Metabolite Cancer
    AST5902 trimesylate is the principal metabolite of Alflutinib (AST2818) both in vitro and in vivo. AST5902 trimesylate exerts antineoplastic activity. Alflutinib is an EGFR inhibitor .
    <em>AST</em>5902 trimesylate
  • HY-15002
    AST 487
    4 Publications Verification

    NVP-AST 487

    		 RET FLT3 VEGFR c-Kit Bcr-Abl Cancer
    AST 487 is a RET kinase inhibitor with IC50 of 880 nM, inhibits RET autophosphorylation and activation of downstream effectors, also inhibits Flt-3 with IC50 of 520 nM.
    <em>AST</em> 487
  • HY-153812
    AST 7062601

    AST070

    		 Others Metabolic Disease
    AST 7062601 (AST070) is a Ucp1 inducer that strongly induces endogenous Ucp1 expression in primary mouse brown adipocytes. Ucp1 refers to uncoupling protein, found in brown and beige fat cells. In mammals, UCP1 oxidizes fatty acids and uncouples ATP production in mitochondria to promote energy dissipation as heat. AST 7062601 can be used to study thermogenic, uncoupled respiration .
    <em>AST</em> 7062601
  • HY-138627
    AST5902

    		Drug Metabolite EGFR Cancer
    AST5902 is the active metabolite of Firmonertinib (HY-112870) (EGFR inhibitor). AST5902 has antineoplastic activity .
    <em>AST</em>5902
  • HY-13427
    Allitinib tosylate

    AST-1306 (TsOH)

    		 EGFR Cancer
    Allitinib tosylate (AST-1306 (TsOH)) is an orally active and irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. Allitinib tosylate also inhibits ErbB4 with an IC50 of 0.8 nM. Allitinib tosylate is an anilino-quinazoline compound and has anti-cancer activity
    Allitinib tosylate
  • HY-15375
    Allitinib

    AST-1306; ALS 1306

    		 EGFR Cancer
    Allitinib (AST-1306) is an orally active and irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. Allitinib also inhibits ErbB4 with an IC50 of 0.8 nM. Allitinib is an anilino-quinazoline compound and has anti-cancer activity .
    Allitinib
  • HY-139785
    Cavrotolimod

    AST-008

    		 Toll-like Receptor (TLR) Others
    Cavrotolimod is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.
    Cavrotolimod
  • HY-139785A
    Cavrotolimod sodium

    AST-008 sodium

    		 Toll-like Receptor (TLR) Others
    Cavrotolimod sodium is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.
    Cavrotolimod sodium
  • HY-112870A
    Firmonertinib mesylate
    2 Publications Verification

    Alflutinib mesylate; Furmonertinib mesylate; AST2818 mesylate

    		 EGFR Cancer
    Firmonertinib (Alflutinib) mesylate is is a potent inhibitor of EGFR. Firmonertinib mesylate inhibits EGFR active mutations as well as the T790M acquired resistant mutation. Firmonertinib has the potential for the research of cancer diseases, especially non-small cell lung cancer (NSCLC) .
    Firmonertinib mesylate
  • HY-112870
    Firmonertinib

    Alflutinib; Furmonertinib; AST2818

    		 EGFR Cancer
    Firmonertinib (Alflutinib) is a potent inhibitor of EGFR. Firmonertinib inhibits EGFR active mutations as well as the T790M acquired resistant mutation. Firmonertinib has the potential for the research of cancer diseases, especially non-small cell lung cancer (NSCLC) .
    Firmonertinib
  • HY-N4033
    Horminone

    7α-Hydroxyroyleanone

    		 Bacterial Infection
    Horminone is an abietan diterpene quinone that can be isolated from Labiatae family. Horminone increases of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) serum levels in vivo. Horminone inhibits the growth of Trypanosoma cruzi and shows antibacterial activity .
    Horminone
  • HY-N6595
    Lucidone A

    		Others Others
    Lucidone A is a lanostanoid isolated from the fruiting bodies of G. resinaceum. lucidone A showed inhibitory effects against the increase of ALT and AST levels in HepG2 cells induced by H2O2 compared to a control group in the range of their maximum non-toxic concentration (MNTC) .
    Lucidone A
  • HY-133528
    OptoBI-1

    		TRP Channel Neurological Disease
    OptoBI-1 is a photochromic TRPC3 agonist, which asts as a photopharmacological tool to control of neuronal firing .
    OptoBI-1
  • HY-P3690
    Ac-Leu-Leu-Norleucinol

    		Proteasome Others
    Ac-Leu-Leu-Norleucinol (ALLN) is a calpain inhibitor, can be used for research of Acetaminophen (HY-66005) induced acute liver damage, and lowers glutamic-oxalacetic transaminease (ALT) and glutamic-pyruvic transaminase (AST) .
    Ac-Leu-Leu-Norleucinol
  • HY-N2638
    Ilexsaponin A

    		Apoptosis Cardiovascular Disease
    Ilexsaponin A, isolated from the root of Ilex pubescens, attenuates ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway. Ilexsaponin A can reduce myocardial infarct size, lower the serum levels of LDH, AST and CK-MB, increase cellular viability and inhibit apoptosis in hypoxia/reoxygenation cardiomyocytes .
    Ilexsaponin A

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