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Results for "

AZ3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	JAK (1) MicroRNA (4)
By Research Areas:	Cancer (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*AZ-3*	JAK	Cancer
AZ-3 is a potent and selective JAK1 inhibitor with an IC₅₀ of 34 nM.

hsa-miR-548az-3p mimic	MicroRNA	Cancer
hsa-miR-548az-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-548az-3p mimic hsa-miR-548az-3p mimic

hsa-miR-548az-3p inhibitor	MicroRNA
hsa-miR-548az-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-548az-3p inhibitor hsa-miR-548az-3p inhibitor

hsa-miR-548az-3p agomir	MicroRNA
hsa-miR-548az-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-548az-3p agomir hsa-miR-548az-3p agomir

hsa-miR-548az-3p antagomir	MicroRNA
hsa-miR-548az-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-548az-3p antagomir hsa-miR-548az-3p antagomir

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