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Results for "

Acridine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (2) Autophagy (1) Bacterial (5) Cholinesterase (ChE) (2) DNA Stain (4) Fluorescent Dye (4) HDAC (2) HIF/HIF Prolyl-Hydroxylase (1) HIV (1) IRE1 (2) Parasite (3) Potassium Channel (1) SARS-CoV (1)
By Research Areas:	Cancer (5) Infection (5) Neurological Disease (2)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101879

Acridine Orange hydrochloride Maximum Cited Publications 16 Publications Verification	DNA Stain Parasite Fluorescent Dye	Others
Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .

HY-D0993

Acridine Orange 10-Nonyl Bromide 1 Publications Verification NonylAcridine orange	Fluorescent Dye	Others
Acridine Orange 10-Nonyl Bromide is a fluorescent probe for cardiolipin (λ_ex: 489 nm, λ_em: 525 nm).

HY-D1660

Acridine homodimer NSC 219743	DNA Stain	Others
Acridine homodimer (NSC 219743), acridine dimer, is a fluorescence dye. Acridine homodimer emits a blue-green fluorescence when bound to DNA. Acridine homodimer has extremely high affinity for AT-rich regions of nucleic acids, can be used for chromosome banding .

HY-D0942

Acridine Orange zinc chloride salt Euchrysine 3RX	Parasite Fluorescent Dye DNA Stain	Others
Acridine Orange (Euchrysine 3RX) zinc chloride salt is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange zinc chloride salt produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .

HY-D0952

Acridine Orange base	Parasite	Others
Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays .

HY-B1741A

Proflavine dihydrochloride 3,6-DiaminoAcridine dihydrochloride	Bacterial Fluorescent Dye	Infection
Proflavine (3,6-Diaminoacridine) dihydrochloride, an acridine dye, is a DNA intercalating agent and Anti-microbial agent. Proflavine dihydrochloride behaves as a pore blocker for Kir3.2. Proflavine dihydrochloride is a potential lead compound for Kir3.2-associated neurological diseases .

HY-U00460

3,6-DMAD hydrochloride	IRE1	Cancer
3,6-DMAD hydrochloride, an acridine derivative, is a potent IRE1α-XBP1s pathway inhibitor. 3,6-DMAD hydrochloride promotes IL-6 secretion via the IRE1α-XBP1s pathway. 3,6-DMAD hydrochloride inhibits IRE1α oligomerization and endoribonuclease (RNase) activity. 3,6-DMAD hydrochloride can be used for research of cancer .

HY-U00460B

3,6-DMAD dihydrochloride	IRE1	Cancer
3,6-DMAD dihydrochloride, an acridine derivative, is a potent IRE1α-XBP1s pathway inhibitor. 3,6-DMAD dihydrochloride promotes IL-6 secretion via the IRE1α-XBP1s pathway. 3,6-DMAD dihydrochloride inhibits IRE1α oligomerization and endoribonuclease (RNase) activity. 3,6-DMAD dihydrochloride can be used for research of cancer .

HY-106991A

Amustaline dihydrochloride S-303 dihydrochloride	HIV Bacterial	Infection
Amustaline (S-303) dihydrochloride, a nucleic acid-targeted alkylator, is an efficient pathogen inactivation agent for blood components containing red blood cells. Amustaline dihydrochloride has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products) .

HY-W007771

Acridone	Bacterial	Infection Cancer
Acridone is an organic compound based on the acridine skeleton. Acridone has antibacterial, antimalarial, antiviral and anti neoplastic activities .

HY-B1741

Proflavine 3,6-DiaminoAcridine
Proflavine, an acridine dye, is a known DNA intercalating agent. Anti-microbial agent . Proflavine behaves as a pore blocker for K_ir3.2. Proflavine is a potential lead compound for K_ir3.2-associated neurological diseases .

HY-B0883

Proflavine hemisulfate 1 Publications Verification Proflavin hemisulfate; 3,6-DiaminoAcridine hemisulfate	Bacterial Potassium Channel Autophagy	Infection Cancer
Proflavine hemisulfate, an acridine dye, is a known DNA intercalating agent. Anti-microbial agent . Proflavine hemisulfate behaves as a pore blocker for K_ir3.2. Proflavine hemisulfate is a potential lead compound for K_ir3.2-associated neurological diseases .

HY-W088075

Acriflavine hydrochloride 4 Publications Verification Acriflavinium chloride hydrochloride	HIF/HIF Prolyl-Hydroxylase Bacterial SARS-CoV	Infection Cancer
Acriflavine hydrochloride (Acriflavinium chloride hydrochloride) is a fluorescent acridine dye that can be used to label nucleic acid . Acriflavine hydrochloride is an antiseptic. Acriflavine hydrochloride is a potent HIF-1 inhibitor, with antitumor activity. Acriflavine hydrochloride has antimicrobial and antiviral activities . Acriflavine hydrochloride is a potent papain-like protease (PL ^pro) inhibitor, which inhibits SARS-CoV-2

HY-146678

HDAC6-IN-5	HDAC Amyloid-β Cholinesterase (ChE)	Neurological Disease
HDAC6-IN-5 (compound 11b) is a potent and BBB-penetrated HDAC6 inhibitor, with an IC₅₀ of 0.025 μM. HDAC6-IN-5 exhibits strong inhibitory activity against Aβ_1-42 self-aggregation and AChE, with IC₅₀ values of 3.0 and 0.72 μM. HDAC6-IN-5 can enhance neurite outgrowth without significant neurotoxicity .

HY-146679

HDAC6-IN-6	HDAC Amyloid-β Cholinesterase (ChE)	Neurological Disease
HDAC6-IN-6 (compound 6a) is a potent and BBB-penetrated HDAC6 inhibitor, with an IC₅₀ of 0.025 μM. HDAC6-IN-6 exhibits strong inhibitory activity against Aβ_1-42 self-aggregation and AChE, with IC₅₀ values of 3.0 and 0.72 μM. HDAC6-IN-6 can enhance neurite outgrowth without significant neurotoxicity .

HY-D0996

LDS-751	DNA Stain	Others
Lds-751 is a nucleic acid stain that mainly detects DNA. Lds-751 is a nucleic acid stain that mainly detects DNA. Lds-751 has a high affinity for DNA and fluorescence is enhanced after binding, but the maximum emission wavelength is 670nm. Lds-751 and Thiazole orange can be used for the differentiation of red blood cells, platelets, reticulocytes, and nucleated cells and can be stimulated at 488nm. Studies have shown that LDS-751 binds almost exclusively to mitochondria when incubated with nucleated living cells. After nucleated Acridine Orange (HY-101879) staining and LDS-751 treatment of cells, confocal microscopy revealed almost no co-location of the cells. Staining with Rhodamine 123 (HY-D0816), a dye known to bind polarized mitochondria, was almost identical to the pattern observed with LDS-751 .

Cat. No.	Product Name	Type

HY-101879

Acridine Orange hydrochloride Maximum Cited Publications 16 Publications Verification	Fluorescent Dyes/Probes
Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .

HY-D0993

Acridine Orange 10-Nonyl Bromide 1 Publications Verification NonylAcridine orange	Fluorescent Dyes/Probes
Acridine Orange 10-Nonyl Bromide is a fluorescent probe for cardiolipin (λ_ex: 489 nm, λ_em: 525 nm).

HY-B0883

Proflavine hemisulfate 1 Publications Verification Proflavin hemisulfate; 3,6-DiaminoAcridine hemisulfate	Fluorescent Dyes/Probes
Proflavine hemisulfate, an acridine dye, is a known DNA intercalating agent. Anti-microbial agent . Proflavine hemisulfate behaves as a pore blocker for K_ir3.2. Proflavine hemisulfate is a potential lead compound for K_ir3.2-associated neurological diseases .

HY-D0942

Acridine Orange zinc chloride salt Euchrysine 3RX	DNA Stain
Acridine Orange (Euchrysine 3RX) zinc chloride salt is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange zinc chloride salt produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .

HY-D0952

Acridine Orange base	Fluorescent Dyes/Probes
Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays .

Acridine Orange base

Fluorescent Dyes/Probes

Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays .

HY-D0996

LDS-751	DNA Stain
Lds-751 is a nucleic acid stain that mainly detects DNA. Lds-751 is a nucleic acid stain that mainly detects DNA. Lds-751 has a high affinity for DNA and fluorescence is enhanced after binding, but the maximum emission wavelength is 670nm. Lds-751 and Thiazole orange can be used for the differentiation of red blood cells, platelets, reticulocytes, and nucleated cells and can be stimulated at 488nm. Studies have shown that LDS-751 binds almost exclusively to mitochondria when incubated with nucleated living cells. After nucleated Acridine Orange (HY-101879) staining and LDS-751 treatment of cells, confocal microscopy revealed almost no co-location of the cells. Staining with Rhodamine 123 (HY-D0816), a dye known to bind polarized mitochondria, was almost identical to the pattern observed with LDS-751 .

LDS-751

DNA Stain

Lds-751 is a nucleic acid stain that mainly detects DNA. Lds-751 is a nucleic acid stain that mainly detects DNA. Lds-751 has a high affinity for DNA and fluorescence is enhanced after binding, but the maximum emission wavelength is 670nm. Lds-751 and Thiazole orange can be used for the differentiation of red blood cells, platelets, reticulocytes, and nucleated cells and can be stimulated at 488nm. Studies have shown that LDS-751 binds almost exclusively to mitochondria when incubated with nucleated living cells. After nucleated Acridine Orange (HY-101879) staining and LDS-751 treatment of cells, confocal microscopy revealed almost no co-location of the cells. Staining with Rhodamine 123 (HY-D0816), a dye known to bind polarized mitochondria, was almost identical to the pattern observed with LDS-751 .

Acridine Orange zinc chloride salt Euchrysine 3RX	DNA Stain
Acridine Orange (Euchrysine 3RX) zinc chloride salt is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange zinc chloride salt produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .

Acridone	Infection Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields	Bacterial
Acridone is an organic compound based on the acridine skeleton. Acridone has antibacterial, antimalarial, antiviral and anti neoplastic activities .

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