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Results for "

Adenosine_deaminase

" in MedChemExpress (MCE) Product Catalog:

31

Inhibitors & Agonists

2

Biochemical Assay Reagents

6

Natural
Products

3

Recombinant Proteins

7

Isotope-Labeled Compounds

4

Antibodies

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-114175

    RnADA

    Adenosine Deaminase Inflammation/Immunology
    Adenosine deaminase (RnADA) (EC 3.5.4.4) is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively.
    Adenosine deaminase, microorganism
  • HY-A0006
    Pentostatin
    Maximum Cited Publications
    9 Publications Verification

    CI-825; Deoxycoformycin

    Adenosine Deaminase Antibiotic Cancer
    Pentostatin (CI-825; Deoxycoformycin) is an irreversible inhibitor of adenosine deaminase with Ki of 2.5 pM.
    Pentostatin
  • HY-D0855A

    Biochemical Assay Reagents Others
    ADA (disodium) is a buffer salt derived from ADA (adenosine deaminase) and is widely used in biochemical research, especially in the preparation of enzyme buffers.
    ADA disodium
  • HY-N7368

    Adenosine Deaminase Neurological Disease Inflammation/Immunology Cancer
    Hibifolin, a flavonol glycoside, is a potential inhibitor of adenosine deaminase (ADA), with a Ki of 49.92 μM. Hibifolin protects neurons against beta-amyloid-induced neurotoxicity .
    Hibifolin
  • HY-114175A

    RnADA, Calf Spleen

    Adenosine Deaminase Inflammation/Immunology
    Adenosine deaminase, Calf Spleen is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively .
    Adenosine deaminase, Calf Spleen
  • HY-122154

    Adenosine Deaminase Inflammation/Immunology
    FR234938 is a non-nucleoside adenosine deaminase inhibitor with an IC50 of 17 nM for recombinant human adenosine deaminase enzyme. FR234938 has anti-rheumatic and anti-inflammatory effects .
    FR234938
  • HY-119048

    2'-Chloropentostatin

    Others Others
    Adechlorin (2'-Chloropentostatin) is an adenosine deaminase inhibitor isolated from actinomycete culture, with potent inhibitory activity against calf intestinal adenosine deaminase, a Ki value that is comparable to other known inhibitors, and can enhance the antiviral activity of Ara-A, and has lower acute toxicity in mice than other analogs.
    Adechlorin
  • HY-120248

    Adenosine Deaminase Cancer
    FR221647 is an orally active non-nucleoside inhibitor of adenosine deaminase. FR221647 is not cytotoxic at a concentration of 100 μM .
    FR221647
  • HY-117260

    Adenosine Deaminase Bacterial Antibiotic Infection Cancer
    Coformycin, a nucleoside antibiotic, is a potent inhibitor of adenosine deaminase (ADA) from Streptomyces species. Coformycin possesses anti-tumor and anti-bacterial activity .
    Coformycin
  • HY-A0006R

    Adenosine Deaminase Antibiotic Cancer
    Pentostatin (Standard) is the analytical standard of Pentostatin. This product is intended for research and analytical applications. Pentostatin (CI-825; Deoxycoformycin) is an irreversible inhibitor of adenosine deaminase with Ki of 2.5 pM.
    Pentostatin (Standard)
  • HY-145443

    Others Cancer
    Fludarabine-Cl has an inhibitory effect on RNA adenosine deaminase 1 (ADAR1) with an IC50 of 0.87 μM and can be used to prevent and/or study cancer or tumor-related diseases .
    Fludarabine-Cl
  • HY-W011552

    Endogenous Metabolite Cardiovascular Disease
    2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities .
    2'-O-Methyladenosine
  • HY-103159

    Adenosine Deaminase Cancer
    1-Deazaadenosine is a potent Adenosine deaminase (ADA) inhibitor with a Ki value of 0.66 μM. 1-Deazaadenosine exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders .
    1-Deazaadenosine
  • HY-103237

    Adenosine Deaminase Neurological Disease
    L-Adenosine is a metabolically stable enantiomeric analog and also is a potential probe. L-Adenosine has weakly inhibitory adenosine deaminase (ADA) activity with an Ki value of 385 μM. L-Adenosine can be used for the research of adenosine uptake and accumulation .
    L-Adenosine
  • HY-N7368R

    Adenosine Deaminase Neurological Disease Inflammation/Immunology Cancer
    Hibifolin (Standard) is the analytical standard of Hibifolin. This product is intended for research and analytical applications. Hibifolin, a flavonol glycoside, is a potential inhibitor of adenosine deaminase (ADA), with a Ki of 49.92 μM. Hibifolin protects neurons against beta-amyloid-induced neurotoxicity .
    Hibifolin (Standard)
  • HY-128790S1

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    4-Methoxyestrone- 13C6 is a 13C-labeled 5'-Guanylic acid. 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and
    4-Methoxyestrone-13C6
  • HY-N5134
    5'-Guanylic acid
    1 Publications Verification

    5'-GMP; 5'-guanosine monophosphate

    Endogenous Metabolite Metabolic Disease
    5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway. 5'-Guanylic acid can form a supramolecular catalyst with iron(III)-hemoglobin that has peroxidase activity .
    5'-Guanylic acid
  • HY-W011552R

    Endogenous Metabolite Cardiovascular Disease
    2'-O-Methyladenosine (Standard) is the analytical standard of 2'-O-Methyladenosine. This product is intended for research and analytical applications. 2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities .
    2'-O-Methyladenosine (Standard)
  • HY-W753672

    Isotope-Labeled Compounds Cardiovascular Disease
    2'-O-Methyl Adenosine-d3 is deuterium labeled 2'-O-Methyl Adenosine. 2'-O-Methyl Adenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyl Adenosine exhibits unique hypotensive activities .
    2'-O-Methyladenosine-d3
  • HY-13599
    Cladribine
    4 Publications Verification

    2-Chloro-2′-deoxyadenosine; CldAdo; 2CdA

    Adenosine Deaminase Apoptosis Cardiovascular Disease Cancer
    Cladribine (2-Chloro-2′-deoxyadenosine), a purine nucleoside analog, is an orally active adenosine deaminase inhibitor. Cladribine functions as an inhibitor of DNA synthesis to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple sclerosis .
    Cladribine
  • HY-105017

    ATL 313; DE 112

    Adenosine Receptor Infection Inflammation/Immunology
    Evodenoson is a selective agonist of the A2A adenosine receptor. Evodenoson’s primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenoson’s protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α) .
    Evodenoson
  • HY-161703

    Adenosine Deaminase Cardiovascular Disease
    2-Hydroxy-3′-O-methyladenosine is a synthetic intermediate product that can be used in the research of ischemic heart disease, cerebrovascular disease, kidney disease, inflammatory allergies and other diseases. 2-phenylamino-N6,2'-O-dimethyladenosine produced from 2-Hydroxy-3′-O-methyladenosine is an inhibitor of adenosine deaminase with a Ki of 13 nM .
    2-Hydroxy-3′-O-methyladenosine
  • HY-N5134R

    5'-GMP (Standard); 5'-guanosine monophosphate (Standard)

    Endogenous Metabolite
    5'-Guanylic acid (Standard) is a standard product of 5'-Guanylic acid (5'-GMP). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway. 5'-Guanylic acid can form a supramolecular catalyst with iron(III)-hemoglobin that has peroxidase activity .
    5'-Guanylic acid (Standard)
  • HY-N5134S1

    5'-GMP-13C10 dilithium; 5'-guanosine monophosphate-13C10 dilithium

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    5'-Guanylic acid- 13C10 (5'-GMP- 13C10 dilithium; 5'-guanosine monophosphate- 13C10) dilithium is 13C-labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
    5'-Guanylic acid-13C10 dilithium
  • HY-N5134S2

    5'-GMP-15N5 dilithium; 5'-guanosine monophosphate-15N5 dilithium

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    5'-Guanylic acid- 15N5 (5'-GMP- 15N5 dilithium; 5'-guanosine monophosphate- 15N5) dilithium is 15N labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
    5'-Guanylic acid-15N5 dilithium
  • HY-N5134S3

    5'-GMP-d12 dilithium; 5'-guanosine monophosphate-d12 dilithium

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    5'-Guanylic acid-d12 (5'-GMP-d12 dilithium; 5'-guanosine monophosphate-d12) dilithium is deuterium labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
    5'-Guanylic acid-d12 dilithium
  • HY-13599R

    Adenosine Deaminase Apoptosis Cardiovascular Disease Cancer
    Cladribine (Standard) is the analytical standard of Cladribine. This product is intended for research and analytical applications. Cladribine (2-Chloro-2′-deoxyadenosine), a purine nucleoside analog, is an orally active adenosine deaminase inhibitor. Cladribine functions as an inhibitor of DNA synthesis to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple sclerosis .
    Cladribine (Standard)
  • HY-103160A
    EHNA hydrochloride
    3 Publications Verification

    Adenosine Deaminase Phosphodiesterase (PDE) Influenza Virus Infection Cardiovascular Disease Neurological Disease Cancer
    EHNA hydrochloride is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2)(IC50=4 μM) and adenosine deaminase (ADA). EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)(IC50:0.8 μM (human), 2 μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA hydrochloride play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects .
    EHNA hydrochloride
  • HY-23789

    2'-O-MOE-rG

    Nucleoside Antimetabolite/Analog Others
    2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA .
    2′-O-(2-Methoxyethyl)guanosine
  • HY-N5134S5

    5'-GMP-13C10,15N5 dilithium; 5'-guanosine monophosphate-13C10,15N5 dilithium

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    5'-Guanylic acid- 13C10, 15N5 (5'-GMP- 13C10, 15N5 dilithium; 5'-guanosine monophosphate- 13C10, 15N5) dilithium is 13C and 15N-labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
    5'-Guanylic acid-13C10,15N5 dilithium
  • HY-N5134S4

    5'-GMP-15N5,d12 dilithium; 5'-guanosine monophosphate-15N5,d12 dilithium

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    5'-Guanylic acid- 15N5,d12 (5'-GMP- 15N5,d12 dilithium; 5'-guanosine monophosphate- 15N5,d12) dilithium is deuterium and 15N labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
    5'-Guanylic acid-15N5,d12 dilithium

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