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Results for "

Advanced+glycation

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (4) Aldose Reductase (7) Amyloid-β (8) Apoptosis (6) Autophagy (2) Bacterial (2) Biochemical Assay Reagents (4) Caspase (2) CDK (1) COX (2) Cytochrome P450 (2) Dipeptidyl Peptidase (4) DNA/RNA Synthesis (1) Drug Intermediate (1) Drug Metabolite (2) EAAT (1) Endogenous Metabolite (8) Environmental Pollutants (1) ERK (2) Fc Receptor (FcR) (1) GABA Receptor (2) GLP Receptor (1) Glycosidase (3) Glyoxalase (GLO) (1) HIV (2) Insulin Receptor (1) Interleukin Related (2) Isotope-Labeled Compounds (3) Keap1-Nrf2 (2) Mitophagy (2) MMP (1) Neurokinin Receptor (2) NF-κB (1) NO Synthase (1) PARP (1) PI3K (1) PKC (1) Polo-like Kinase (PLK) (1) Reactive Oxygen Species (ROS) (5) Reference Standards (10) Serotonin Transporter (1) TNF Receptor (2) Toll-like Receptor (TLR) (2)
By Research Areas:	Cancer (19) Cardiovascular Disease (8) Endocrinology (5) Infection (2) Inflammation/Immunology (15) Metabolic Disease (38) Neurological Disease (13)

By Targets:

Adrenergic Receptor (4)

Aldose Reductase (7)

Amyloid-β (8)

Apoptosis (6)

Autophagy (2)

Bacterial (2)

Biochemical Assay Reagents (4)

Caspase (2)

CDK (1)

COX (2)

Cytochrome P450 (2)

Dipeptidyl Peptidase (4)

DNA/RNA Synthesis (1)

Drug Intermediate (1)

Drug Metabolite (2)

EAAT (1)

Endogenous Metabolite (8)

Environmental Pollutants (1)

ERK (2)

Fc Receptor (FcR) (1)

GABA Receptor (2)

GLP Receptor (1)

Glycosidase (3)

Glyoxalase (GLO) (1)

HIV (2)

Insulin Receptor (1)

Interleukin Related (2)

Isotope-Labeled Compounds (3)

Keap1-Nrf2 (2)

Mitophagy (2)

MMP (1)

Neurokinin Receptor (2)

NF-κB (1)

NO Synthase (1)

PARP (1)

PI3K (1)

PKC (1)

Polo-like Kinase (PLK) (1)

Reactive Oxygen Species (ROS) (5)

Reference Standards (10)

Serotonin Transporter (1)

TNF Receptor (2)

Toll-like Receptor (TLR) (2)

By Research Areas:

Cancer (19)

Cardiovascular Disease (8)

Endocrinology (5)

Infection (2)

Inflammation/Immunology (15)

Metabolic Disease (38)

Neurological Disease (13)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-141537

ABR-238901 5 Publications Verification	Toll-like Receptor (TLR)	Inflammation/Immunology
ABR-238901 is an orally active and potent S100A8/A9 blocker and inhibits S100A8/A9 interaction with its receptors RAGE (receptor for advanced glycation endproducts) and TLR4 (toll-like receptor 4). ABR-238901 has the potential for myocardial infarction (MI) research .

HY-50682

Azeliragon Maximum Cited Publications 15 Publications Verification TTP488; PF-04494700	Amyloid-β	Neurological Disease Cancer
Azeliragon (TTP488) is an orally bioavailable inhibitor of the *receptor for advanced glycation* end products (RAGE)** in development as a potential treatment to slow disease progression with mild Alzheimer’s disease (AD) . Azeliragon also can cross the blood-brain barrier (BBB) .

HY-B1041

Aminoguanidine hydrochloride 5+ Cited Publications Pimagedine hydrochloride; GER-11; Aminoguanidinium chloride	NO Synthase Apoptosis ERK	Neurological Disease Metabolic Disease Inflammation/Immunology
Aminoguanidine (Pimagedine) hydrochloride is an inhibitor of diamine oxidase (DAO) and nitric oxide synthase (NOS). Aminoguanidine hydrochloride can reduce the formation of advanced glycation end products (AGEs). Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on Doxorubicin (HY-15142)-induced cell apoptosis. Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in the research of diabetic nephropathy .

HY-106024B

Alagebrium chloride 5+ Cited Publications ALT711	Endogenous Metabolite	Metabolic Disease
Alagebrium chloride (ALT711) is an advanced glycation end product (AGE) inhibitor.

HY-N0033

Poliumoside Maximum Cited Publications 8 Publications Verification	Aldose Reductase	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Poliumoside, a caffeoylated phenylpropanoid glycoside, is isolated from Brandisia hancei stems and leaves. Poliumoside is an advanced glycation end product (AGE) formation and rat lens aldose reductase (RLAR) inhibitor, with IC₅₀s of 19.69 and 8.47 μM, respectively. Poliumoside also has antiinflammatory and antioxidant activity .

HY-B1235

Acetohydroxamic acid 1 Publications Verification N-Hydroxyacetamide	Bacterial HIV	Infection Inflammation/Immunology
Acetohydroxamic acid is the inhibitor for bacterial and plant urease that can be used for chronic urinary tract infections. Acetohydroxamic acid selectively inhibits arachidonic acid 5-lipoxygenase that is useful in the research of asthma. Acetohydroxamic acid inhibits the formation of advanced glycation end products, and reduces oxidative stress and inflammatory responses. Acetohydroxamic acid exhibits antiviral activity against HIV .

HY-N7426

3-Deoxyglucosone 3-Deoxy-D-glucosone	GLP Receptor	Metabolic Disease
3-Deoxyglucosone (3-Deoxy-D-glucosone) is a reactive intermediate of the Maillard reaction and the polyol pathway. 3-Deoxyglucosone rapidly reacts with protein amino groups to form advanced glycation end products (AGEs), such as imidazolone, it is the most specific AGE for 3-DG. 3-Deoxyglucosone synergizes with low glucose to potentiate GLP-1 secretion and is considered as a biomarker for diabetes .

HY-NP165

Advanced glycation end products AGEs	Biochemical Assay Reagents	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Advanced glycation end products (AGEs) are a series of stable compounds generated through non-enzymatic reactions between reducing sugars and proteins, lipids, or nucleic acids. Advanced glycation end products are often used as targets to evaluate the inhibitory effects of anti-glycation compounds. Advanced glycation end products can be applied to research on diabetes, cardiovascular and cerebrovascular diseases, inflammation, aging, and other conditions .

HY-14892A

Gemigliptin tartrate LC15-0444 tartrate	Dipeptidyl Peptidase	Metabolic Disease
Gemigliptin tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor, with an IC₅₀ of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibits potent anti-glycation properties. Gemigliptin tartrate can be used for the research of advanced glycation end products (AGE)-related diabetic complications .

HY-B1392

Esmolol hydrochloride 3 Publications Verification	Adrenergic Receptor Caspase Apoptosis Aldose Reductase Neurokinin Receptor	Cardiovascular Disease Endocrinology Cancer
Esmolol hydrochloride is an ultra-short-acting cardioselective β1-adrenergic blocker. Esmolol hydrochloride exerts its antiarrhythmic effect by activating Neurokinin 1 Receptor. Esmolol hydrochloride attenuates post resuscitation myocardial dysfunction. Esmolol hydrochloride improves diabetic wound healing by inhibiting aldose reductase and the production of advanced glycation end products and promoting fibroblast migration. Esmolol hydrochloride can be used to study cardiac diseases such as arrhythmias and diabetic foot ulcers .

HY-W286743

Nε-(Carboxymethyl)-L-lysine 1 Publications Verification CML; N6-(Carboxymethyl)-L-lysine; Nε-(1-Carboxymethyl)-L-lysine	Polo-like Kinase (PLK) ERK NF-κB	Cancer
Nε-(Carboxymethyl)-L-lysine (CML) is an orally active advanced glycation end product. Nε-(Carboxymethyl)-L-lysine upregulates the expression of PLK1 and CEP20, and induces the activation of RAGE and ERK/NFκB. Nε-(Carboxymethyl)-L-lysine drives centrosome amplification. Nε-(Carboxymethyl)-L-lysine induces malignant transformation of hepatocytes and promotes the development of hepatocellular carcinoma. Nε-(Carboxymethyl)-L-lysine induces epithelial-mesenchymal transition in osteosarcoma cells and enhances their migration and invasion properties .

HY-B1745

Pyridoxylamine 5+ Cited Publications	Endogenous Metabolite	Metabolic Disease
Pyridoxylamine is an advanced glycation end production (AGEs) and lipoxidation end products (ALEs) inhibitor, to protect against diabetes-induced retinal vascular lesions.

HY-129611

Bromelain	Apoptosis	Inflammation/Immunology Cancer
Bromelain is an anti-inflammatory agent derived from pineapple stem that acts through down-regulation of plasma kininogen, inhibition of Prostaglandin E2 expression, degradation of advanced glycation end product receptors and regulation of angiogenic biomarkers as well as antioxidant action upstream in the COX-pathway . Bromelain exhibits various fibrinolytic, antiedematous, antithrombotic, and anti-inflammatory activities. Bromelain also possesses some anticancerous activities and promotes apoptotic cell death .

HY-P2268

RAGE antagonist peptide 4 Publications Verification	Amyloid-β	Inflammation/Immunology Cancer
RAGE antagonist peptide is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide (RAP) possesses anti-tumor and anti-inflammatory activities .

HY-W019724

2,2-Dihydroxyacetic acid	Drug Intermediate Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease Cancer
2,2-Dihydroxyacetic acid is an endogenous metabolite, which is the monohydrate of Glyoxylic Acid. 2,2-Dihydroxyacetic acid may participate in the microbial glyoxylate cycle, induce an increase in reactive oxygen species, promote cell differentiation, and modify proteins to form advanced glycation end products (AGEs) (HY-NP165). 2,2-Dihydroxyacetic acid is associated with metabolic diseases such as primary hyperoxaluria .

HY-N4089

Quercetin 3-gentiobioside	Aldose Reductase Cytochrome P450	Metabolic Disease Cancer
Quercetin 3-gentiobioside is a flavonoid found in Artemisia iwayomogi. Quercetin 3-gentiobioside inhibits aromatase with an K_i of 46.77 nM. Quercetin 3-gentiobioside inhibits aldose reductase (AR) and the formation of advanced glycation end products (AGEs), with IC₅₀ values of 10.60 μM and 109.46 μM, respectively. Quercetin 3-gentiobioside inhibits proliferation of cancer cells and fibroblast-like synoviocytes. Quercetin 3-gentiobioside can be used for the research of cancer, such as lung carcinoma .

HY-124750

NecroX-7	TNF Receptor Interleukin Related Toll-like Receptor (TLR) Reactive Oxygen Species (ROS)	Cardiovascular Disease Inflammation/Immunology
NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease (GVHD) research .

HY-B1745A

Pyridoxylamine dihydrochloride 5+ Cited Publications	Endogenous Metabolite	Metabolic Disease
Pyridoxylamine dihydrochloride is an advanced glycation end production (AGEs) and lipoxidation end products (ALEs) inhibitor, to protect against diabetes-induced retinal vascular lesions .

HY-76383

LR-90	COX	Metabolic Disease Inflammation/Immunology
LR-90 is an advanced glycation end product (AGE) inhibitor, inhibits inflammatory responses in human monocytes . LR-90 is also used in the research of diabetic animal model .

HY-N4170

Chebulic acid 2 Publications Verification	Keap1-Nrf2 Reactive Oxygen Species (ROS)	Metabolic Disease
Chebulic acid is a phenolic acid compound isolated from Terminalia chebula with strong antioxidant activity, which breaks protein cross-links induced by advanced glycation end products (AGEs) and inhibits the formation of AGEs. Chebulic acid is effective in controlling elevated metabolic parameters, oxidative stress, and liver damage, supporting its beneficial role in asthma, diabetes, and liver protection .

HY-N1470

Plantagoside	Glycosidase	Metabolic Disease
Plantagoside is a flavanone glucoside found in Plantago asiatica seeds, acting as a specific non-competitive α-mannosidase inhibitor with IC₅₀ values of 5 μM and a K_i of 2.7 μM (jack bean). Plantagoside suppresses antibody response and Concanavalin A (HY-P2149)-induced lymphocyte proliferation in mouse spleen cells. Plantagoside inhibits the Maillard reaction, advanced glycation end product formation, and glycation-dependent protein-protein cross-link formation. Plantagoside can be used for the research of diabetes .

HY-107207

Kaempferol 3-neohesperidoside 3 Publications Verification Kaempferol 3-O-neohesperidoside	Insulin Receptor PI3K PKC	Metabolic Disease
Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside) is a flavonoid. Kaempferol 3-neohesperidoside mimics insulin action via the PI3K/PKC pathway, significantly promoting glucose uptake and increasing muscle glycogen content in rat soleus muscles. Kaempferol 3-neohesperidoside also exhibits anti-glycation activity. Kaempferol 3-neohesperidoside binds to albumin through hydrogen bonding and hydrophobic interactions, and inhibits the formation of advanced glycation end products. Kaempferol 3-neohesperidoside can be used in studies of diabetes and its related complications .

HY-P2268A

RAGE antagonist peptide TFA 4 Publications Verification	Amyloid-β	Inflammation/Immunology Cancer
RAGE antagonist peptide TFA is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide TFA prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide TFA possesses anti-tumor and anti-inflammatory activities .

HY-114883

Homocarnosine L-Homocarnosine	GABA Receptor Endogenous Metabolite	Neurological Disease Inflammation/Immunology
Homocarnosine is a dipeptide of γ-aminobutyric acid (GABA) and histidine unique to brain. Homocarnosine is an inhibitory neuromodulator synthesized in the neuron from GABA and exhibiting anticonvulsant effects .Homocarnosine has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation .

HY-14892

Gemigliptin LC15-0444	Dipeptidyl Peptidase	Metabolic Disease Cancer
Gemigliptin (LC15-0444 ) is a highly selective, reversible and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor, with an IC₅₀ of 10.3 nM for human recombinant DPP-4. Gemigliptin exhibits potent anti-glycation properties. Gemigliptin can be used for the research of advanced glycation end products (AGE)-related diabetic complications .

HY-113033

Pentosidine	Others Biochemical Assay Reagents	Neurological Disease Metabolic Disease Inflammation/Immunology
Pentosidine is a fluorescent advanced glycation end product (AGE) and cross-linker. Pentosidine is a fluorescent cross-linked structure formed by lysine and arginine in sugar oxidation reactions, and it is commonly found in collagen, skin, bone, lens and plasma proteins . Pentosidine is used in research related to type 1 diabetes, brown cataracts, rheumatoid arthritis, atherosclerosis and neurodegenerative diseases .

HY-N7628

Cassiaside C Toralactone 9-O-β-D-gentiobioside	Endogenous Metabolite	Metabolic Disease
Cassiaside C (Toralactone 9-O-β-D-gentiobioside) is a naphthopyrone isolated from the seed of Cassia tora and has inhibitory activity on advanced glycation end products (AGE) formation in vitro .

HY-Y0785

Glyoxal (40% w/w in water)	Drug Metabolite	Metabolic Disease
Glyoxal is a cytotoxic α-oxoaldehyde. Glyoxal induces cell damage and promotes protein glycation to form advanced glycation end-products (AGEs). Glyoxal is promising for research of oxidative stress-related diseases (such as atherosclerosis, cataract, Alzheimer's disease), and the formation of calcium oxalate kidney stones .

HY-114883A

Homocarnosine TFA L-Homocarnosine TFA	GABA Receptor Endogenous Metabolite	Neurological Disease
Homocarnosine TFA is a dipeptide of γ-aminobutyric acid (GABA) and histidine unique to brain. Homocarnosine TFA is an inhibitory neuromodulator synthesized in the neuron from GABA and exhibiting anticonvulsant effects . Homocarnosine TFA has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation .

HY-W585874

Nε-(Carboxyethyl)lysine	EAAT Apoptosis	Neurological Disease Metabolic Disease
Nε-(Carboxyethyl) lysine is an advanced glycation end product (AGE). Nε-(Carboxyethyl) lysine induces cross-linking between proteins, thereby affecting protein structure and function and causing protein denaturation. Nε-(Carboxyethyl) lysine binds to the RAGE receptor, affects cell signal transduction, and regulates processes such as inflammatory responses, cell proliferation, and apoptosis. Nε-(Carboxyethyl) lysine affects glutamate transporters, reduces glutamate uptake and S100β protein secretion, influences neurotransmission in the nervous system, and exhibits diabetes-related neurotoxicity .

HY-N8375

Sieboldin	Others	Metabolic Disease
Sieboldin is a dihydrochalcone, which inhibits the production of advanced glycation end products (AGE) produced by bovine serum albumins (BSA), has free radical scavenging activity and cytotoxicity in cancer cell lines, and is also used to capture of methylglyoxal (MGO) from Malus baccata .

HY-Y0785S

Glyoxal-d2	Isotope-Labeled Compounds Drug Metabolite	Metabolic Disease
Glyoxal-d₂ is the deuterium labeled Glyoxal (HY-Y0785). Glyoxal is a cytotoxic α-oxoaldehyde. Glyoxal induces cell damage and promotes protein glycation to form advanced glycation end-products (AGEs). Glyoxal is promising for research of oxidative stress-related diseases (such as atherosclerosis, cataract, Alzheimer's disease), and the formation of calcium oxalate kidney stones .

HY-B1235R

Acetohydroxamic acid (Standard) N-Hydroxyacetamide (Standard)	Reference Standards Bacterial HIV	Infection Inflammation/Immunology
Acetohydroxamic acid (Standard) is the analytical standard of Acetohydroxamic acid. This product is intended for research and analytical applications. Acetohydroxamic acid is the inhibitor for bacterial and plant urease that can be used for chronic urinary tract infections. Acetohydroxamic acid selectively inhibits arachidonic acid 5-lipoxygenase that is useful in the research of asthma. Acetohydroxamic acid inhibits the formation of advanced glycation end products, and reduces oxidative stress and inflammatory responses. Acetohydroxamic acid exhibits antiviral activity against HIV .

HY-B1745R

Pyridoxylamine (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Pyridoxylamine (Standard) is the analytical standard of Pyridoxylamine. This product is intended for research and analytical applications. Pyridoxylamine is an advanced glycation end production (AGEs) and lipoxidation end products (ALEs) inhibitor, to protect against diabetes-induced retinal vascular lesions.

HY-N7069

4-Isopropylbenzyl alcohol	Environmental Pollutants	Cancer
4-Isopropylbenzyl alcohol is a chemical composition of the essential oils from the leaves and flowers of Camellia nitidissima. C. nitidissima possess multiple biological activities including antioxidant activity, anticancer activity, and cytotoxicity as well as inhibiting the formation of advanced glycation end-products .

HY-14892C

Gemigliptin hydrochloride LC15-0444 hydrochloride	Dipeptidyl Peptidase	Metabolic Disease Cancer
Gemigliptin hydrochloride is the hydrochloride salt of Gemigliptin (HY-14892). Gemigliptin hydrochloride is a highly selective, reversible and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor, with an IC₅₀ of 10.3 nM for human recombinant DPP-4. Gemigliptin hydrochloride exhibits potent anti-glycation properties. Gemigliptin hydrochloride can be used for the research of advanced glycation end products (AGE)-related diabetic complications .

HY-50682S

Azeliragon-d9 TTP488-d₉; PF-04494700-d₉	Isotope-Labeled Compounds Amyloid-β	Neurological Disease Endocrinology
Azeliragon-d₉ (TTP488-d₉) is the deuterium labeled Azeliragon (HY-50682). Azeliragon (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression with mild Alzheimer’s disease (AD) . Azeliragon also can cross the blood-brain barrier (BBB) .

HY-146619

RAGE/SERT-IN-1	Amyloid-β Serotonin Transporter	Neurological Disease
RAGE/SERT-IN-1 is a potent and orally active advanced glycation end products (RAGE) and serotonin transporter (SERT) inhibitor with IC₅₀s of 8.26 μM and 31.09 nM, respectively. RAGE/SERT-IN-1 exhibits significant neuroprotective effect against Aβ_25-35-induced neuronal damage and alleviates depressive behavior of mice. RAGE/SERT-IN-1 can be used for researching the comorbidity of Alzheimer's disease and depression .

HY-N6883

6-Methoxytricin	Aldose Reductase	Metabolic Disease
6-Methoxytricin (Compound 6) is an flavonoid isolated from Artemisia iwayomogi. 6-Methoxytricin (Compound 6) is an inhibitor on aldose reductase (AR) and advanced glycation endproduct (AGE) formation activities with IC₅₀ values of 30.29 μM and 134.88 μM, respectively. 6-Methoxytricin (Compound 6) has potential as an anti-diabetic complications agent .

HY-14892B

Gemigliptin tartrate hydrate LC15-0444 tartrate hydrate	Dipeptidyl Peptidase	Metabolic Disease
Gemigliptin (LC15-0444 ) tartrate hydrate is a selective, reversible and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor, with an IC₅₀ of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate hydrate exhibits potent anti-glycation properties. Gemigliptin tartrate hydrate can be used for the research of advanced glycation end products (AGE)-related diabetic complications .

HY-B1392A

Esmolol	Adrenergic Receptor Caspase Apoptosis Aldose Reductase Neurokinin Receptor	Cardiovascular Disease Endocrinology Cancer
Esmolol is an ultra-short-acting cardioselective β1-adrenergic blocker. Esmolol exerts its antiarrhythmic effect by activating Neurokinin 1 Receptor. Esmolol attenuates post resuscitation myocardial dysfunction. Esmolol improves diabetic wound healing by inhibiting aldose reductase and the production of advanced glycation end products and promoting fibroblast migration. Esmolol can be used to study cardiac diseases such as arrhythmias and diabetic foot ulcers .

HY-131528

Tenilsetam CAS 997	TNF Receptor	Neurological Disease Metabolic Disease
Tenilsetam (CAS 997) is an antidementia compound. Tenilsetam is an advanced glycation end product (AGE) inhibitor. Tenilsetam inhibits early retinopathy in experimental diabetes rats .

HY-B1745AR

Pyridoxylamine dihydrochloride (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Pyridoxylamine (dihydrochloride) (Standard) is the analytical standard of Pyridoxylamine (dihydrochloride). This product is intended for research and analytical applications. Pyridoxylamine dihydrochloride is an advanced glycation end production (AGEs) and lipoxidation end products (ALEs) inhibitor, to protect against diabetes-induced retinal vascular lesions .

HY-N12071

Lucidin-ω-Me ether	Others	Others
Lucidin-ω-Me ether (Compound 2) can be isolated from the roots of Knoxia valerianoides. Lucidin-ω-Me ether inhibits the advanced glycation end products (AGEs) formation in vitro(IC₅₀: 62.79 μM) .

HY-50682A

Azeliragon dihydrochloride TTP488 dihydrochloride; PF-04494700 dihydrochloride	Amyloid-β	Neurological Disease Cancer
Azeliragon dihydrochloride (TTP488) is an orally bioavailable inhibitor of the *receptor for advanced glycation* end products (RAGE)** in development as a potential treatment to slow disease progression with mild Alzheimer’s disease (AD) . Azeliragon dihydrochloride also can cross the blood-brain barrier (BBB) .

HY-171336

TRC4186	Interleukin Related	Metabolic Disease
TRC4186 is a potent advanced glycation end-product (AGE) inhibitor. TRC4186 demonstrates AGE-breaking activities in vitro and improvement in the endothelial and myocardial function in animal models of diabetes mellitus. TRC4186 can be used for complications associated with diabetes research .

HY-50682R

Azeliragon (Standard) TTP488 (Standard); PF-04494700 (Standard)	Amyloid-β Reference Standards	Neurological Disease Cancer
Azeliragon (Standard) is the analytical standard of Azeliragon. This product is intended for research and analytical applications. Azeliragon (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression with mild Alzheimer’s disease (AD) . Azeliragon also can cross the blood-brain barrier (BBB) .

HY-113033A

Pentosidine TFA	Biochemical Assay Reagents	Neurological Disease Metabolic Disease
Pentosidine TFA is an advanced glycation end product (AGE) and cross-linked substance with fluorescent properties. Pentosidine TFA is present in various human tissues and can serve as a biomarker for diabetes, aging, uremia, protein accumulation damage, and non-enzymatic modification of long-lived proteins in the Maillard reaction. It aids in gaining a deeper understanding of the overall role of the Maillard reaction in aging and disease .

HY-168957

RuDiOBn	MMP Reactive Oxygen Species (ROS)	Others
RuDiOBn scanvages DPPH and ABTS free radicals (13.2% and 5.9% clearance at 100 μg/mL), exhibits low antioxidant activity. RuDiOBn inhibits the collagen glycation, reduces the formation of advanced glycation end products (AGEs) with an IC₅₀ of 2.45 μg/mL. RuDiOBn enhances the proliferation and migration of fibroblasts, stimulates the synthesis of collagen, promoting the skin repair and regeneration. RuDiOBn also inhibits collagenase .

HY-N0033R

Poliumoside (Standard)	Reference Standards Aldose Reductase	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Poliumoside (Standard) is the analytical standard of Poliumoside. This product is intended for research and analytical applications. Poliumoside, a caffeoylated phenylpropanoid glycoside, is isolated from Brandisia hancei stems and leaves. Poliumoside is an advanced glycation end product (AGE) formation and rat lens aldose reductase (RLAR) inhibitor, with IC₅₀s of 19.69 and 8.47 μM, respectively. Poliumoside also has antiinflammatory and antioxidant activity .

Cat. No.	Product Name	Type

HY-NP165

Advanced glycation end products

AGEs

Biochemical Assay Reagents

Advanced glycation end products (AGEs) are a series of stable compounds generated through non-enzymatic reactions between reducing sugars and proteins, lipids, or nucleic acids. Advanced glycation end products are often used as targets to evaluate the inhibitory effects of anti-glycation compounds. Advanced glycation end products can be applied to research on diabetes, cardiovascular and cerebrovascular diseases, inflammation, aging, and other conditions .

HY-W286743

Nε-(Carboxymethyl)-L-lysine

1 Publications Verification

CML; N6-(Carboxymethyl)-L-lysine; Nε-(1-Carboxymethyl)-L-lysine

Biochemical Assay Reagents

Nε-(Carboxymethyl)-L-lysine (CML) is an orally active advanced glycation end product. Nε-(Carboxymethyl)-L-lysine upregulates the expression of PLK1 and CEP20, and induces the activation of RAGE and ERK/NFκB. Nε-(Carboxymethyl)-L-lysine drives centrosome amplification. Nε-(Carboxymethyl)-L-lysine induces malignant transformation of hepatocytes and promotes the development of hepatocellular carcinoma. Nε-(Carboxymethyl)-L-lysine induces epithelial-mesenchymal transition in osteosarcoma cells and enhances their migration and invasion properties .

Cat. No.	Product Name	Target	Research Area

HY-P2268

RAGE antagonist peptide 4 Publications Verification	Amyloid-β	Inflammation/Immunology Cancer
RAGE antagonist peptide is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide (RAP) possesses anti-tumor and anti-inflammatory activities .

HY-P2268A

RAGE antagonist peptide TFA 4 Publications Verification	Amyloid-β	Inflammation/Immunology Cancer
RAGE antagonist peptide TFA is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide TFA prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide TFA possesses anti-tumor and anti-inflammatory activities .

HY-114883

Homocarnosine L-Homocarnosine	GABA Receptor Endogenous Metabolite	Neurological Disease Inflammation/Immunology
Homocarnosine is a dipeptide of γ-aminobutyric acid (GABA) and histidine unique to brain. Homocarnosine is an inhibitory neuromodulator synthesized in the neuron from GABA and exhibiting anticonvulsant effects .Homocarnosine has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation .

HY-114883A

Homocarnosine TFA L-Homocarnosine TFA	GABA Receptor Endogenous Metabolite	Neurological Disease
Homocarnosine TFA is a dipeptide of γ-aminobutyric acid (GABA) and histidine unique to brain. Homocarnosine TFA is an inhibitory neuromodulator synthesized in the neuron from GABA and exhibiting anticonvulsant effects . Homocarnosine TFA has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation .

Cat. No.	Product Name	Target	Research Area	Image

HY-P992465

SIWA318H	Fc Receptor (FcR)	Cancer
SIWA318H is an adbanvced glycation end product (AGE) specific antibody. SIWA318H selectively binds to advanced glycation end product biomarkers, human FcγRIIIa, and pancreatic cancer cells, and cancer-associated fibroblasts. SIWA318H suppresses tumor growth in mouse PSN1 xenografts. SIWA318H can be used for the research of pancreatic cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-106024B

Alagebrium chloride 5+ Cited Publications ALT711	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Alagebrium chloride (ALT711) is an advanced glycation end product (AGE) inhibitor.

HY-N0033

Poliumoside Maximum Cited Publications 8 Publications Verification	Cardiovascular Disease Classification of Application Fields Callicarpa formosana Rolfe Plants Simple Phenylpropanols Verbenaceae Phenols Polyphenols Scrophulariaceae Phenylpropanoids Inflammation/Immunology Disease Research Fields Brandisia hancei Hook. f. Source Classification	Aldose Reductase
Poliumoside, a caffeoylated phenylpropanoid glycoside, is isolated from Brandisia hancei stems and leaves. Poliumoside is an advanced glycation end product (AGE) formation and rat lens aldose reductase (RLAR) inhibitor, with IC₅₀s of 19.69 and 8.47 μM, respectively. Poliumoside also has antiinflammatory and antioxidant activity .

HY-N7426

3-Deoxyglucosone 3-Deoxy-D-glucosone	Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Source Classification	GLP Receptor
3-Deoxyglucosone (3-Deoxy-D-glucosone) is a reactive intermediate of the Maillard reaction and the polyol pathway. 3-Deoxyglucosone rapidly reacts with protein amino groups to form advanced glycation end products (AGEs), such as imidazolone, it is the most specific AGE for 3-DG. 3-Deoxyglucosone synergizes with low glucose to potentiate GLP-1 secretion and is considered as a biomarker for diabetes .

HY-B1745

Pyridoxylamine 5+ Cited Publications	Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Disease markers Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Pyridoxylamine is an advanced glycation end production (AGEs) and lipoxidation end products (ALEs) inhibitor, to protect against diabetes-induced retinal vascular lesions.

HY-W019724

2,2-Dihydroxyacetic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Drug Intermediate Reactive Oxygen Species (ROS)
2,2-Dihydroxyacetic acid is an endogenous metabolite, which is the monohydrate of Glyoxylic Acid. 2,2-Dihydroxyacetic acid may participate in the microbial glyoxylate cycle, induce an increase in reactive oxygen species, promote cell differentiation, and modify proteins to form advanced glycation end products (AGEs) (HY-NP165). 2,2-Dihydroxyacetic acid is associated with metabolic diseases such as primary hyperoxaluria .

HY-N4089

Quercetin 3-gentiobioside	Flavonols Structural Classification Flavonoids other families Classification of Application Fields Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Source Classification	Aldose Reductase Cytochrome P450
Quercetin 3-gentiobioside is a flavonoid found in Artemisia iwayomogi. Quercetin 3-gentiobioside inhibits aromatase with an K_i of 46.77 nM. Quercetin 3-gentiobioside inhibits aldose reductase (AR) and the formation of advanced glycation end products (AGEs), with IC₅₀ values of 10.60 μM and 109.46 μM, respectively. Quercetin 3-gentiobioside inhibits proliferation of cancer cells and fibroblast-like synoviocytes. Quercetin 3-gentiobioside can be used for the research of cancer, such as lung carcinoma .

HY-B1745A

Pyridoxylamine dihydrochloride 5+ Cited Publications	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Pyridoxylamine dihydrochloride is an advanced glycation end production (AGEs) and lipoxidation end products (ALEs) inhibitor, to protect against diabetes-induced retinal vascular lesions .

HY-N4170

Chebulic acid 2 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Combretaceae Phenols Polyphenols Metabolic Disease Terminalia chebula Retz. Plants Disease Research Fields Source Classification	Keap1-Nrf2 Reactive Oxygen Species (ROS)
Chebulic acid is a phenolic acid compound isolated from Terminalia chebula with strong antioxidant activity, which breaks protein cross-links induced by advanced glycation end products (AGEs) and inhibits the formation of AGEs. Chebulic acid is effective in controlling elevated metabolic parameters, oxidative stress, and liver damage, supporting its beneficial role in asthma, diabetes, and liver protection .

HY-N1470

Plantagoside	Plantaginaceae Structural Classification Flavonoids Classification of Application Fields Flavonones Phenols Polyphenols Metabolic Disease Plantago asiatica L. Plants Disease Research Fields Source Classification	Glycosidase
Plantagoside is a flavanone glucoside found in Plantago asiatica seeds, acting as a specific non-competitive α-mannosidase inhibitor with IC₅₀ values of 5 μM and a K_i of 2.7 μM (jack bean). Plantagoside suppresses antibody response and Concanavalin A (HY-P2149)-induced lymphocyte proliferation in mouse spleen cells. Plantagoside inhibits the Maillard reaction, advanced glycation end product formation, and glycation-dependent protein-protein cross-link formation. Plantagoside can be used for the research of diabetes .

HY-107207

Kaempferol 3-neohesperidoside 3 Publications Verification Kaempferol 3-O-neohesperidoside	Flavonols Structural Classification Flavonoids Typhaceae Classification of Application Fields Typha orientalis Presl Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Source Classification	Insulin Receptor PI3K PKC
Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside) is a flavonoid. Kaempferol 3-neohesperidoside mimics insulin action via the PI3K/PKC pathway, significantly promoting glucose uptake and increasing muscle glycogen content in rat soleus muscles. Kaempferol 3-neohesperidoside also exhibits anti-glycation activity. Kaempferol 3-neohesperidoside binds to albumin through hydrogen bonding and hydrophobic interactions, and inhibits the formation of advanced glycation end products. Kaempferol 3-neohesperidoside can be used in studies of diabetes and its related complications .

HY-114883

Homocarnosine L-Homocarnosine	Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	GABA Receptor Endogenous Metabolite
Homocarnosine is a dipeptide of γ-aminobutyric acid (GABA) and histidine unique to brain. Homocarnosine is an inhibitory neuromodulator synthesized in the neuron from GABA and exhibiting anticonvulsant effects .Homocarnosine has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation .

HY-113033

Pentosidine	Structural Classification Natural Products Disease markers Endogenous metabolite Source Classification	Others Biochemical Assay Reagents
Pentosidine is a fluorescent advanced glycation end product (AGE) and cross-linker. Pentosidine is a fluorescent cross-linked structure formed by lysine and arginine in sugar oxidation reactions, and it is commonly found in collagen, skin, bone, lens and plasma proteins . Pentosidine is used in research related to type 1 diabetes, brown cataracts, rheumatoid arthritis, atherosclerosis and neurodegenerative diseases .

HY-N7628

Cassiaside C Toralactone 9-O-β-D-gentiobioside	Cassia tora (L.) Roxb. Monophenols Classification of Application Fields Leguminosae Phenols Metabolic Disease Plants Disease Research Fields Source Classification	Endogenous Metabolite
Cassiaside C (Toralactone 9-O-β-D-gentiobioside) is a naphthopyrone isolated from the seed of Cassia tora and has inhibitory activity on advanced glycation end products (AGE) formation in vitro .

HY-114883A

Homocarnosine TFA L-Homocarnosine TFA	Structural Classification Natural Products Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification	GABA Receptor Endogenous Metabolite
Homocarnosine TFA is a dipeptide of γ-aminobutyric acid (GABA) and histidine unique to brain. Homocarnosine TFA is an inhibitory neuromodulator synthesized in the neuron from GABA and exhibiting anticonvulsant effects . Homocarnosine TFA has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation .

HY-N8375

Sieboldin	Balanophora involucrata Hook. f. Plants Balanophoraceae Saccharides Monosaccharides Source Classification	Others
Sieboldin is a dihydrochalcone, which inhibits the production of advanced glycation end products (AGE) produced by bovine serum albumins (BSA), has free radical scavenging activity and cytotoxicity in cancer cell lines, and is also used to capture of methylglyoxal (MGO) from Malus baccata .

HY-B1745R

Pyridoxylamine (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Disease markers Nervous System Disorder Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Pyridoxylamine (Standard) is the analytical standard of Pyridoxylamine. This product is intended for research and analytical applications. Pyridoxylamine is an advanced glycation end production (AGEs) and lipoxidation end products (ALEs) inhibitor, to protect against diabetes-induced retinal vascular lesions.

HY-N7069

4-Isopropylbenzyl alcohol	Camellia nitidissima Structural Classification Natural Products Classification of Application Fields Plants Disease Research Fields Source Classification Theaceae Cancer	Environmental Pollutants
4-Isopropylbenzyl alcohol is a chemical composition of the essential oils from the leaves and flowers of Camellia nitidissima. C. nitidissima possess multiple biological activities including antioxidant activity, anticancer activity, and cytotoxicity as well as inhibiting the formation of advanced glycation end-products .

HY-N6883

6-Methoxytricin	Flavonoids other families Classification of Application Fields Flavones Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Source Classification	Aldose Reductase
6-Methoxytricin (Compound 6) is an flavonoid isolated from Artemisia iwayomogi. 6-Methoxytricin (Compound 6) is an inhibitor on aldose reductase (AR) and advanced glycation endproduct (AGE) formation activities with IC₅₀ values of 30.29 μM and 134.88 μM, respectively. 6-Methoxytricin (Compound 6) has potential as an anti-diabetic complications agent .

HY-B1745AR

Pyridoxylamine dihydrochloride (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Pyridoxylamine (dihydrochloride) (Standard) is the analytical standard of Pyridoxylamine (dihydrochloride). This product is intended for research and analytical applications. Pyridoxylamine dihydrochloride is an advanced glycation end production (AGEs) and lipoxidation end products (ALEs) inhibitor, to protect against diabetes-induced retinal vascular lesions .

HY-N12071

Lucidin-ω-Me ether	Quinones Anthraquinones Rubiaceae Knoxia valerianoides Thorel ex Pitard Plants Source Classification	Others
Lucidin-ω-Me ether (Compound 2) can be isolated from the roots of Knoxia valerianoides. Lucidin-ω-Me ether inhibits the advanced glycation end products (AGEs) formation in vitro(IC₅₀: 62.79 μM) .

HY-N0033R

Poliumoside (Standard)	Structural Classification Simple Phenylpropanols Verbenaceae Phenols Polyphenols Scrophulariaceae Callicarpa formosana Rolfe Phenylpropanoids Plants Brandisia hancei Hook. f. Source Classification	Reference Standards Aldose Reductase
Poliumoside (Standard) is the analytical standard of Poliumoside. This product is intended for research and analytical applications. Poliumoside, a caffeoylated phenylpropanoid glycoside, is isolated from Brandisia hancei stems and leaves. Poliumoside is an advanced glycation end product (AGE) formation and rat lens aldose reductase (RLAR) inhibitor, with IC₅₀s of 19.69 and 8.47 μM, respectively. Poliumoside also has antiinflammatory and antioxidant activity .

HY-N4089R

Quercetin 3-gentiobioside (Standard)	Flavonols Structural Classification Flavonoids other families Phenols Polyphenols Plants Source Classification	Reference Standards Aldose Reductase Cytochrome P450
Quercetin 3-gentiobioside (Standard) is the analytical standard of Quercetin 3-gentiobioside (HY-N4089). This product is intended for research and analytical applications. Quercetin 3-gentiobioside is a flavonoid found in Artemisia iwayomogi. Quercetin 3-gentiobioside inhibits aromatase with an K_i of 46.77 nM. Quercetin 3-gentiobioside inhibits aldose reductase (AR) and the formation of advanced glycation end products (AGEs), with IC₅₀ values of 10.60 μM and 109.46 μM, respectively. Quercetin 3-gentiobioside inhibits proliferation of cancer cells and fibroblast-like synoviocytes. Quercetin 3-gentiobioside can be used for the research of cancer, such as lung carcinoma .

HY-107207R

Kaempferol 3-neohesperidoside (Standard) Kaempferol 3-O-neohesperidoside (Standard)	Flavonols Structural Classification Flavonoids Typhaceae Typha orientalis Presl Phenols Polyphenols Plants Source Classification	Reference Standards Others
Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside) Standard is the analytical standard of Kaempferol 3-neohesperidoside (HY-107207). This product is intended for research and analytical applications. Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside) is a flavonoid. Kaempferol 3-neohesperidoside mimics insulin action via the PI3K/PKC pathway, significantly promoting glucose uptake and increasing muscle glycogen content in rat soleus muscles. Kaempferol 3-neohesperidoside also exhibits anti-glycation activity. Kaempferol 3-neohesperidoside binds to albumin through hydrogen bonding and hydrophobic interactions, and inhibits the formation of advanced glycation end products. Kaempferol 3-neohesperidoside can be used in studies of diabetes and its related complications .

HY-N13261

Brickellin	Structural Classification Flavonoids Chrysosplenium grayanum Maxim. Flavones Saxifragaceae Plants Source Classification	Others
Brickellin is an antioxidant agent that can be isolated from Varronia curassavica Jacq.. Brickellin inhibits advanced glycation end products (AGEs) formation, protein crosslinking, and oxidative damage to proteins. Brickellin can be used for the research of diabetes .

HY-N18965

Formyline	Structural Classification Alkaloids Pyrrole Alkaloids Animals Source Classification	Biochemical Assay Reagents
Formyline (Compound 8) is a Maillard reaction product (glycated compound). Formyline is an advanced glycation end product formed by the reaction of lysine with 3-deoxypentosone, pentose, disaccharide degradation products or glucuronic acid. Formyline is commonly found in heat-processed foods such as milk, baked goods and beer, and can serve as a characteristic marker for food processing .

HY-N4170R

Chebulic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Combretaceae Phenols Polyphenols Terminalia chebula Retz. Plants Source Classification	Reference Standards Keap1-Nrf2 Reactive Oxygen Species (ROS)
Chebulic acid (Standard) is the analytical standard of Chebulic acid (HY-N4170). This product is intended for research and analytical applications. Chebulic acid is a phenolic acid compound isolated from Terminalia chebula with strong antioxidant activity, which breaks protein cross-links induced by advanced glycation end products (AGEs) and inhibits the formation of AGEs. Chebulic acid is effective in controlling elevated metabolic parameters, oxidative stress, and liver damage, supporting its beneficial role in asthma, diabetes, and liver protection .

HY-N1470R

Plantagoside (Standard)	Plantaginaceae Structural Classification Flavonoids Flavonones Phenols Polyphenols Plantago asiatica L. Plants Source Classification	Reference Standards Glycosidase
Plantagoside (Standard) is the analytical standard of Plantagoside (HY-N1470). This product is intended for research and analytical applications. Plantagoside is a flavanone glucoside found in Plantago asiatica seeds, acting as a specific non-competitive α-mannosidase inhibitor with IC₅₀ values of 5 μM and a K_i of 2.7 μM (jack bean). Plantagoside suppresses antibody response and Concanavalin A (HY-P2149)-induced lymphocyte proliferation in mouse spleen cells. Plantagoside inhibits the Maillard reaction, advanced glycation end product formation, and glycation-dependent protein-protein cross-link formation. Plantagoside can be used for the research of diabetes .

Cat. No.	Product Name	Chemical Structure

HY-Y0785S

Glyoxal-d2
Glyoxal-d₂ is the deuterium labeled Glyoxal (HY-Y0785). Glyoxal is a cytotoxic α-oxoaldehyde. Glyoxal induces cell damage and promotes protein glycation to form advanced glycation end-products (AGEs). Glyoxal is promising for research of oxidative stress-related diseases (such as atherosclerosis, cataract, Alzheimer's disease), and the formation of calcium oxalate kidney stones .

HY-50682S

Azeliragon-d9
Azeliragon-d₉ (TTP488-d₉) is the deuterium labeled Azeliragon (HY-50682). Azeliragon (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression with mild Alzheimer’s disease (AD) . Azeliragon also can cross the blood-brain barrier (BBB) .

HY-B1392S

Esmolol-d7 hydrochloride

Esmolol-d₇ hydrochloride is the deuterium labeled Esmolol hydrochloride (HY-B1392). Esmolol hydrochloride is an ultra-short-acting cardioselective β1-adrenergic blocker. Esmolol hydrochloride exerts its antiarrhythmic effect by activating Neurokinin 1 Receptoraldose reductase) and the production of advanced glycation end products and promoting fibroblast migration. Esmolol hydrochloride can be used to study cardiac diseases such as arrhythmias and diabetic foot ulcers .

Host:	Rabbit (2)
Reactivity:	Human (2) Rat (2) Mouse (2)
Application:	IHC-P (2) ICC/IF (1) mIHC (1) IF-Tissue (1) IHC-F (1) WB (2) FC (1)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Polyclonal (1) Monoclonal (1) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81086

	RAGE Antibody Advanced glycosylation end product specific receptor; Advanced glycosylation end product-specific receptor; AGER; EC 2.7.11.22; LE 9211 A antigen; LE-9211-A antigen; MGC22357; MOK; RAGE 1; RAGE1; MOK protein kinase; Receptor for advanced glycation endproducts; Renal tumor antigen 1; Renal tumor antigen; Renal cell carcinoma antigen (MOK protein kinase); Renal tumor antigen 1; RAGE_HUMAN.	WB, IHC-P, IHC-F, ICC/IF, FC	Human, Mouse, Rat
	RAGE Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to RAGE.

HY-P81086A

	RAGE Antibody(YA3549) Advanced glycosylation end product specific receptor; Advanced glycosylation end product-specific receptor; AGER; EC 2.7.11.22; LE 9211 A antigen; LE-9211-A antigen; MGC22357; MOK; RAGE 1; RAGE1; MOK protein kinase; Receptor for advanced glycation endproducts; Renal tumor antigen 1; Renal tumor antigen; Renal cell carcinoma antigen (MOK protein kinase); Renal tumor antigen 1; RAGE_HUMAN.	WB, IHC-P, IF-Tissue, mIHC	Human, Mouse, Rat
	RAGE Antibody(YA3549) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RAGE.

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