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Algo bio Inhibitors

" in MedChemExpress (MCE) Product Catalog:

32

Inhibitors & Agonists

2

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2

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3

Biochemical Assay Reagents

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4

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-118810

    TGF-β Receptor Cancer
    BIO-013077-01 is a pyrazole TGF-β inhibitor .
    <em>BIO</em>-013077-01
  • HY-103035

    Phosphodiesterase (PDE) Cancer
    BIO-32546 (example 12b, S-isomer) is an autotaxin (ATX) modulator (IC50: 1 nM), extracted from the patent US20170158687A1 .
    <em>BIO</em>-32546
  • HY-122663A

    TNF Receptor Apoptosis Metabolic Disease
    BIO8898 is a potent CD40-CD154 inhibitor. BIO8898 inhibits soluble CD40L binding to CD40-Ig with an IC50 value of 25 µM. BIO8898 inhibits CD40L-induced apoptosis .
    <em>BIO</em>8898
  • HY-D2258

    Fluorescent Dye Others
    Bio-17-ATP is a substrate that can be used for AMPylation assays .
    <em>Bio</em>-17-ATP
  • HY-162359

    IRAK Neurological Disease Inflammation/Immunology
    BIO-7488 is a potent, selective, oral active and CNS-penetrant IRAK4 inhibitor with the IC50 of 0.6 nM and > 30 μM for IRAK4 and hERG, respectively .
    <em>BIO</em>-7488
  • HY-115448

    Bacterial Infection
    Bio-AMS is a potent bacterial biotin protein ligase inhibitor. Bio-AMS possesses selective activity against Mycobacterium tuberculosis (Mtb) and arrests fatty acid and lipid biosynthesis .
    <em>Bio</em>-AMS
  • HY-123802

    Integrin Cancer
    BIO7662 is a specific α4β1 antagonist. BIO7662 can be used to study α4β1 integrin-ligand interactions .
    <em>BIO</em>7662
  • HY-155486

    Others Cancer
    HCy-AAN-Bio is a tumor-targeted hemicyanine (HCy) probe for Fluorescent/photoacoustic (FL/PA) imaging of legumain in vivo. Legumain can specifically cleave HCy-AAN-Bio with the generation of FL/PA signal. HCy-AAN-Bio is a powerful tool for early diagnosis of associated cancer .
    HCy-AAN-<em>Bio</em>
  • HY-115448A

    Bacterial Infection
    Bio-AMS (TFA) is a potent bacterial biotin protein ligase inhibitor. Bio-AMS (TFA) possesses selective activity against Mycobacterium tuberculosis (Mtb) and arrests fatty acid and lipid biosynthesis .
    <em>Bio</em>-AMS TFA
  • HY-131933

    Others Others
    DCP-Bio3 is a biotinylated probe that can detect labeled proteins in polyacrylamide gels. DCP-Bio3 can be used in research for the identification of oxidized and modified proteins .
    DCP-<em>Bio</em>3
  • HY-107589A
    BIO5192 hydrate
    1 Publications Verification

    Integrin Inflammation/Immunology
    BIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor (Kd<10 pM). BIO5192 hydrate selectively binds to α4β1 (IC50=1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels .
    <em>BIO</em>5192 hydrate
  • HY-107589
    BIO5192
    1 Publications Verification

    Integrin Inflammation/Immunology
    BIO5192 is a selective and potent integrin α4β1 (VLA-4) inhibitor (Kd<10 pM). BIO5192 selectively binds to α4β1 (IC50=1.8 nM) over a range of other integrins. BIO5192 results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels .
    <em>BIO</em>5192
  • HY-15356
    BIO-acetoxime
    1 Publications Verification

    BIA

    GSK-3 Apoptosis HSV Infection Neurological Disease Inflammation/Immunology
    BIO-acetoxime (BIA) is a potent and selective GSK-3 inhibitor, with IC50s of both 10 nM for GSK-3α/β. BIO-acetoxime has anticonvulsant and anti-infection activity.
    <em>BIO</em>-acetoxime
  • HY-14126
    BIO-1211
    2 Publications Verification

    Integrin Inflammation/Immunology
    BIO-1211 is a highly selective and orally active α4β1 (VLA-4) inhibitor, with IC50 values of 4 nM and 2 μM for α4β1 and α4β7, respectively .
    <em>BIO</em>-1211
  • HY-122663

    TNF Receptor Cancer
    (Rac)-BIO8898 is a CD40-CD154 co-stimulatory interaction inhibitor. (Rac)-BIO8898 inhibits CD154 binding to CD40-Ig with an IC50 of 25 μM .
    (Rac)-<em>BIO</em>8898
  • HY-128867

    CDK Cancer
    bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7. THZ1 is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM .
    <em>bio</em>-THZ1
  • HY-121035

    7-Bromoindirubin-3-Oxime

    CDK GSK-3 Neurological Disease
    7BIO (7-Bromoindirubin-3-Oxime) is the derivate of indirubin. 7BIO (7-Bromoindirubin-3-Oxime) has inhibitory effects against cyclin-dependent kinase-5 (CDK5) and glycogen synthase kinase-3β (GSK3β). 7BIO (7-Bromoindirubin-3-Oxime) inhibits Aβ oligomer-induced neuroinflammation, synaptic impairments, tau hyper-phosphorylation, activation of astrocytes and microglia, and attenuates Aβ oligomer-induced cognitive impairments in mice [1].
    7<em>BIO</em>
  • HY-114903

    GSK-​3 Inhibitor X

    GSK-3 CDK Neurological Disease Metabolic Disease Cancer
    (E/Z)-BIO-acetoxime (GSK-3 Inhibitor X) is a potent and selective GSK-3α/β inhibitor, with an IC50 of 10 nM. (E/Z)-BIO-acetoxime shows more than 200-flod selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B (IC50=2.4, 4.3, 63 μM) .
    (E/Z)-<em>BIO</em>-acetoxime
  • HY-B1937

    bio-Soft S 101 sodium

    Sodium dodecylbenzenesulfonate (Bio-Soft S 101 sodium) is a nonionic surfactant commonly used in a variety of applications for cleaning and treating industrial equipment. It has good cleaning power and environmental compatibility, and can effectively remove oil, dirt and other forms of contamination. In addition, in textile, paper, leather and other industries, the compound can also be used for fixing and stabilizing dyes and colors. Although the compound has no direct application in the medical field, it plays an important role in industry and laboratory research.
    Sodium dodecylbenzenesulfonate
  • HY-10580
    GSK 3 Inhibitor IX
    Maximum Cited Publications
    10 Publications Verification

    6-Bromoindirubin-3'-oxime; bio; MLS 2052

    GSK-3 CDK Apoptosis Cancer
    GSK 3 Inhibitor IX (6-Bromoindirubin-3'-oxime; BIO) is a potent, selective, reversible and ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex with IC50s of 5 nM/320 nM/80 nM for (GSK-3α/β)/CDK1/CDK5, respectively.
    GSK 3 Inhibitor IX
  • HY-15905

    N-Ethyl-N-sulfopropylaniline sodium salt

    Fluorescent Dye Others
    ALPS(N-Ethyl-N-sulfopropylaniline sodium salt) is a bio-chemical reagents/chromogenic reagent.
    ALPS
  • HY-123638

    Others Inflammation/Immunology
    6-hydroxykaempferol 3,6,7-tri-O-β-D-glucoside is a bio-active flavonoid from Carthamus tinctorius with antioxidant capacities in vitro .
    6-Hydroxykaempferol 3,6,7-tri-O-β-D-glucoside
  • HY-151752

    ADC Linker Others
    Mal-AMCHC-N-Propargylamide is a click chemistry reagent containing an azide group. Mal-AMCHC-N-Propargylamide can be a bio-conjugation reagent for antibody-agent-conjugate synthesis using Click-Chemistry .
    Mal-AMCHC-N-Propargylamide
  • HY-W017132

    Histone Demethylase Cancer
    2,4-PDCA (2,4 pyridine dicarboxylic acid) is a broad-spectrum inhibitor of 2OG oxygenase, including JmjC domain-containing family of histone demethylases (JHDMs). 2,4-PDCA is a target chemical in the field of bio-based plastics .
    2,4-PDCA
  • HY-B0216S

    17α-Ethynylestradiol-d4; Ethynylestradiol-d4

    Estrogen Receptor/ERR Endogenous Metabolite Endocrinology Cancer
    Ethynyl Estradiol-d4 is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Ethynyl Estradiol-d4
  • HY-108298

    PP 5; Perfluorodecahydronaphthalene

    Others Others
    Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears . Perfluorodecalin is a non-toxic, non-flammable, thermally stable, non-bio-accumulating O2-carrier and used as artificial blood . Perfluorodecalin enhances bone regeneration and cell viability .
    Perfluorodecalin
  • HY-W010177

    Biochemical Assay Reagents Others
    Ethyl heptanoate, Ethyl heptanoate is commonly used as a fragrance ingredient in a variety of products, including food, beverages, and personal care products, it can also be used as a solvent, and a building block for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, in addition , due to its low toxicity and biodegradability, Ethyl heptanoate has been investigated for its potential use as a bio-based solvent, as well as for its potential antimicrobial properties against certain bacteria and fungi.
    Ethyl heptanoate
  • HY-128676

    H-​L-​Lys(Poc)​-​OH hydrochloride

    Amino Acid Derivatives Cancer
    N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals . N-ε-propargyloxycarbonyl-L-lysine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    N-ε-propargyloxycarbonyl-L-lysine hydrochloride
  • HY-139014
    N-ε-propargyloxycarbonyl-L-lysine
    1 Publications Verification

    H-​L-​Lys(Poc)​-​OH

    Fluorescent Dye Cancer
    N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals . N-ε-propargyloxycarbonyl-L-lysine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    N-ε-propargyloxycarbonyl-L-lysine
  • HY-N1446C

    Biochemical Assay Reagents Others
    Sorbitan monooleate is a renewable polyol with unique molecular structures for the development and design of bio-based waterborne polyurethane (WPU) with versatility and excellent mechanical properties. Sorbitan monooleate can be used as an excipient, such as nonionic surfactants, emulsifiers. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
    Sorbitan monooleate
  • HY-W040144

    Fluorescent Dye Others
    Bromocresol green is a pH-sensitive triphenylmethane dye commonly used for the determination of protein and albumin in serum. Bromocresol green is a bio-based dye with a yellow-green to blue-green color. Bromocresol green turns yellow (λmax=435 nm, protonated form) when placed in acidic solution (e.g. pH=4.15), and turns blue in basic solution (λmax=615 nm, deprotonated form). Bromocresol green is widely used as a pH indicator in the field of biochemical analysis. In addition, Bromocresol green is also used to detect the concentration of molecules such as creatinine, and to judge the viability of cells .
    Bromocresol green
  • HY-W093282

    Soybean oil epoxide

    Biochemical Assay Reagents Others
    Epoxidized soya bean oil (ESBO) is a vegetable oil-derived organic compound used as a plasticizer and stabilizer in various applications. It is produced by epoxidation of soybean oil, which introduces epoxy groups into the fatty acid chains of the oil. ESBO is a viscous, pale yellow liquid that is soluble in many organic solvents, such as chloroform and ethanol, but insoluble in water. It is commonly used as a plasticizer in polyvinyl chloride (PVC) products, including toys, food packaging materials and medical devices. In addition to its plasticizing properties, ESBO acts as an antioxidant and UV stabilizer, helping to prevent degradation and discoloration of PVC products over time. ESBOs have been investigated for their potential use in biodegradable plastics and as bio-based alternatives to traditional petroleum-derived plasticizers.
    Epoxidized soya bean oil

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