1. Search Result
Search Result
Results for "

Alkyl

" in MedChemExpress (MCE) Product Catalog:

343

Inhibitors & Agonists

2

Screening Libraries

1

Fluorescent Dye

3

Biochemical Assay Reagents

1

Peptides

7

Natural
Products

3

Recombinant Proteins

5

Isotope-Labeled Compounds

75

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-136160

    E3 Ligase Ligand-Linker Conjugates Cancer
    Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride can be used to design the PROTACs .
    Thalidomide 4'-oxyacetamide-<em>alkyl</em>-C2-amine hydrochloride
  • HY-128961

    Drug-Linker Conjugates for ADC Cancer
    MC-Alkyl-Hydrazine Modified MMAF is a agent-linker conjugate for ADC with potent antitumor activity by using the Modified MMAF (a tubulin inhibitor), linked via the noncleavable MC-Alkyl-Hydrazine .
    MC-<em>Alkyl</em>-Hydrazine Modified MMAF
  • HY-13956S1

    Isotope-Labeled Compounds PPAR Ferroptosis Metabolic Disease Cancer
    Pioglitazone-d4 (alkyl) (U 72107-d4 (alkyl)) is the deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively[1][2].
    Pioglitazone-d4 (<em>alkyl</em>)
  • HY-161132

    Ligands for E3 Ligase Others
    Lenalidomide 4'-alkyl-C5-azide is a functionalized cerebellar ligand for PROTAC development that contains an E3 ligand and an alkyl LC5 ligand with terminal azides that can be coupled to a target protein ligand .
    Lenalidomide 4'-<em>alkyl</em>-C5-azide
  • HY-161131

    Ligands for E3 Ligase Apoptosis Molecular Glues Inflammation/Immunology
    Lenalidomide 4'-alkyl-C3-azide (compound 4a) is a click chemical modified Lenalidomide (HY-A0003) that can be used to synthesize PROTACs. Lenalidomide is an orally active immunomodulator and a ligand for the ubiquitin E3 ligase cereblon (CRBN). Lenalidomide 4'-alkyl-C3-azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition reactions (SPAAC) can also occur with molecules containing DBCO or BCN groups .
    Lenalidomide 4'-<em>alkyl</em>-C3-azide
  • HY-140341A

    PROTAC Linkers Others
    Sulfo-NHS-Acetate sodium is an alkyl chain-based PROTAC linker. Sulfo-NHS-Acetate sodium can be used in the synthesis of PROTACs .
    Sulfo-NHS-Acetate sodium
  • HY-W570890

    DNA/RNA Synthesis Others
    2'-O-MOE-5-Me-C (Bz) is a nucleotide for the stereoselective synthesis of nucleoside alkyl phosphonates .
    2'-O-MOE-5-Me-C(Bz)
  • HY-151665

    ADC Linker Others
    Alkyne-PEG2-iodide is a click chemistry reagent with terminal alkyne and alkyl iodide groups.
    Alkyne-PEG2-iodide
  • HY-132004

    PROTAC Linkers Cancer
    Tos-O-C4-NH-Boc is an alkyl ether-based PROTAC linker can be used in the synthesis of PROTACs, such as BSJ-03-204 (HY-136250) .
    Tos-O-C4-NH-Boc
  • HY-130470

    PROTAC Linkers Cancer
    Chloroacetamido-PEG4-C2-Boc is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
    Chloroacetamido-PEG4-C2-Boc
  • HY-127008

    Fluorescent Dye Others
    N-Butylfluorescein is an alkyl-substituted fluorescein, can be used for synthesis of fluorogenic substrates for assaying phosphatidylinositol-specific phospholipase C .
    N-Butylfluorescein
  • HY-140239

    PROTAC Linkers Cancer
    Amino-PEG4-benzyl ester is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
    Amino-PEG4-benzyl ester
  • HY-141406

    PROTAC Linkers Cancer
    m-PEG5-2-methylacrylate is a PEG- and Alkyl/ester-based PROTAC linker can be used in the synthesis of PROTACs .
    m-PEG5-2-methylacrylate
  • HY-141404

    PROTAC Linkers Cancer
    m-PEG4-CH2-methyl ester is a PEG- and Alkyl/ester-based PROTAC linker can be used in the synthesis of PROTACs .
    m-PEG4-CH2-methyl ester
  • HY-140406

    PROTAC Linkers Cancer
    Aminooxy-PEG3-C2-NH-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
    Aminooxy-PEG3-C2-NH-Boc
  • HY-140596

    PROTAC Linkers Cancer
    m-PEG3-S-PEG3-Boc is a PEG- and Alkyl/ether -based PROTAC linker can be used in the synthesis of PROTACs .
    m-PEG3-S-PEG3-Boc
  • HY-N7330

    HIV Integrase HIV Infection
    Integracin B is a potent dimeric alkyl aromatic inhibitor of HIV-1 integrase discovered from the screening of fungal extracts using an in vitro assay. Integracin B inhibits both coupled and strand transfer activity of HIV-1 integrase .
    Integracin B
  • HY-139661

    PROTAC Linkers Cancer
    Boc-bipiperidine-ethynylbenzoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of ARD-61 . Boc-bipiperidine-ethynylbenzoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Boc-bipiperidine-ethynylbenzoic acid
  • HY-120775

    ADC Linker PROTAC Linkers Cancer
    Boc-NH-PEG1-CH2CH2COOH is a cleavable (1 unit PEG) ADC linker and also a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of antibody-drug conjugates (ADCs) or PROTACs .
    Boc-NH-PEG1-CH2CH2COOH
  • HY-130420

    PROTAC Linkers Cancer
    Azido-PEG5-PFP ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG5-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    Azido-PEG5-PFP ester
  • HY-130742

    PROTAC Linkers Cancer
    Azido-PEG8-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG8-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    Azido-PEG8-Boc
  • HY-43721

    PROTAC Linkers Cancer
    N-Boc-4-pentyne-1-amine is a PROTAC linker, which refers to the alkyl chain composition. N-Boc-4-pentyne-1-amine can be used in the synthesis of the PROTAC MG-277 (HY-130122) . N-Boc-4-pentyne-1-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    N-Boc-4-pentyne-1-amine
  • HY-130693

    PROTAC Linkers Cancer
    Azido-PEG5-CH2CO2-PFP is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-PFP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    Azido-PEG5-CH2CO2-PFP
  • HY-133044

    PROTAC Linkers Cancer
    Boc-Pip-alkyne-Ph-COOH is a PROTAC linker, which refers to the alkyl/ether composition. Boc-Pip-alkyne-Ph-COOH can be used in the synthesis of a series of PROTACs, such as ARD-266 (HY-133020). ARD-266 effectively induces degradation of androgen receptor (AR) protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines with DC50 values of 0.2-1 nM . Boc-Pip-alkyne-Ph-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Boc-Pip-alkyne-Ph-COOH
  • HY-130184

    ADC Linker PROTAC Linkers Cancer
    Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    Azido-PEG8-NHS ester
  • HY-130474

    ADC Linker PROTAC Linkers Cancer
    Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    Azido-PEG6-NHS ester
  • HY-42618

    ADC Linker PROTAC Linkers Cancer
    Azido-PEG4-CH2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-CH2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    Azido-PEG4-CH2-Boc
  • HY-130985

    PROTAC Linkers Cancer
    9-Decyn-1-ol is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. 9-Decyn-1-ol can be used to conjugate GDC-0068 with Lenalidomide to generate INY-03-041. INY-03-041 is a potent, highly selective and PROTAC-based pan-Akt degrader. INY-03-041 inhibits Akt1, Akt2 and Akt3 with IC50s of 2.0 nM, 6.8 nM and 3.5 nM, respectively . 9-Decyn-1-ol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    9-Decyn-1-ol
  • HY-42489

    ADC Linker PROTAC Linkers Cancer
    N3-PEG3-CH2CH2-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG3-CH2CH2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    N3-PEG3-CH2CH2-Boc
  • HY-102054

    FAAH Cardiovascular Disease
    Acetylhydrolase-IN-1 is a 1-Alkyl-2-acetylglycerophosphocholine esterase (Alkylacetyl-GPC: acetylhydrolase) inhibtor.
    Acetylhydrolase-IN-1
  • HY-N8082

    HSV Infection
    Stearyl gallate is an alkyl gallate with a long alkyl chain (carbon number of 18). Stearyl gallate has an antioxidant activity, and a weak antiviral activity against HSV-1 .
    Stearyl gallate
  • HY-W100681

    Others Others
    2'-Hydroxy-5'-methylacetophenone belongs to the class of organic compounds known as alkyl-phenylketones. These are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group.
    2'-Hydroxy-5'-methylacetophenone
  • HY-N8055

    Others Others
    Bancroftinone, a natural product, belongs to the class of alkyl-phenylketones .
    Bancroftinone
  • HY-162130

    Bacterial Infection
    Antibacterial agent 176 (Compound 6f) is a potent PqsR antagonist. Antibacterial agent 176 has a good inhibitory effect on P. aeruginosa CF, and a significant inhibitory effect on the production of pyocyanin, 2-alkyl-4 (1H) -quinolones .
    Antibacterial agent 176
  • HY-141263

    PROTAC Linkers Cancer
    Methyltetrazine-acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
    Methyltetrazine-acid
  • HY-130458

    EGS crosslinker

    PROTAC Linkers Cancer
    EGNHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
    EGNHS
  • HY-W014831

    PROTAC Linkers Cancer
    11-Aminoundecanoic acid is an alkyl chain based PROTAC linker can be used in the synthesis of PROTACs.
    11-Aminoundecanoic acid
  • HY-119343

    PROTAC Linkers Cancer
    Biotin-PFP ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
    Biotin-PFP ester
  • HY-124318

    PROTAC Linkers Cancer
    SMPH Crosslinker is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
    SMPH Crosslinker
  • HY-140341

    PROTAC Linkers Cancer
    Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
    Sulfo-NHS-Acetate
  • HY-141176

    PROTAC Linkers Cancer
    TCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
    TCO-amine
  • HY-141260

    PROTAC Linkers Cancer
    Methyltetrazine-propylamine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
    Methyltetrazine-propylamine
  • HY-140338

    PROTAC Linkers Cancer
    Benzenedimethanamine-diethylamine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
    Benzenedimethanamine-diethylamine
  • HY-141175

    PROTAC Linkers Cancer
    TCO-PNB ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
    TCO-PNB ester
  • HY-141186

    PROTAC Linkers Cancer
    TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
    TCO-OH
  • HY-130887

    PROTAC Linkers Cancer
    (+)-Biotin-SLC is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
    (+)-Biotin-SLC
  • HY-130888

    (+)-Biotin 4-nitrophenyl ester

    PROTAC Linkers Cancer
    (+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
    (+)-Biotin-ONP
  • HY-141165

    PROTAC Linkers Cancer
    TCO-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
    TCO-NHS ester
  • HY-130893

    PROTAC Linkers Cancer
    Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
    Biotin-EDA
  • HY-138467

    PROTAC Linkers Cancer
    Mal-PFP ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
    Mal-PFP ester

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: