Search Result

Pathways Recommended:	TGF-beta/Smad
Targets Recommended:	Integrin PGC-1α 5 alpha Reductase TGF-beta/Smad β-catenin IFNAR TGF-β Receptor Beta-secretase Dopamine β-hydroxylase CRM1 PD-1/PD-L1 Mps1 PAI-1 PDK-1 IRE1 Wee1 URAT1 Ack1 sFRP-1 MALT1 IGF-1R MCHR1 (GPR24) Keap1-Nrf2 Adrenergic Receptor Amyloid-β E1/E2/E3 Enzyme c-Fms GPR40 EGFR IRAK EAAT2 Adenosine Receptor P-glycoprotein FXR PTEN Oct3/4 PIKfyve

Results for "Alpha 7 beta 1 integrin Inhibitors" in MCE Product Catalog:

By Targets:	5 alpha Reductase (1) Adrenergic Receptor (6) Amyloid-β (4) GPR40 (1) IFNAR (2) Integrin (59) AChE (1) ADC Cytotoxin (1) Androgen Receptor (1) Antibiotic (2) Apoptosis (11) Aromatase (1) Autophagy (7) Bacterial (9) Bcl-2 Family (1) Bcr-Abl (1) Calcium Channel (1) CaMK (1) Casein Kinase (1) Complement System (1) Drug-Linker Conjugates for ADC (1) DYRK (2) Endogenous Metabolite (11) Ephrin Receptor (1) Factor Xa (1) Ferroptosis (1) Fungal (1) GABA Receptor (1) GLUT (1) HIV (2) Influenza Virus (1) Leukotriene Receptor (1) Lipoxygenase (1) Melanocortin Receptor (2) mGluR (1) Microtubule/Tubulin (1) MMP (1) nAChR (2) NF-κB (1) Nucleoside Antimetabolite/Analog (2) Opioid Receptor (2) p38 MAPK (1) Parasite (1) Phosphatase (1) PI3K (1) PI4K (1) PKA (1) PKC (1) Potassium Channel (1) PROTAC Linker (10) Reactive Oxygen Species (1) Reverse Transcriptase (1) SARS-CoV (1) Sodium Channel (1) Thrombin (1) TNF Receptor (1) TRP Channel (1) Tyrosinase (2) VD/VDR (6) Virus Protease (1)
By Research Areas:	Cancer (72) Cardiovascular Disease (23) Endocrinology (12) Infection (14) Inflammation/Immunology (43) Metabolic Disease (22) Neurological Disease (17)

By Targets:

5 alpha Reductase (1)

Adrenergic Receptor (6)

Amyloid-β (4)

GPR40 (1)

IFNAR (2)

Integrin (59)

AChE (1)

ADC Cytotoxin (1)

Androgen Receptor (1)

Antibiotic (2)

Apoptosis (11)

Aromatase (1)

Autophagy (7)

Bacterial (9)

Bcl-2 Family (1)

Bcr-Abl (1)

Calcium Channel (1)

CaMK (1)

Casein Kinase (1)

Complement System (1)

Drug-Linker Conjugates for ADC (1)

DYRK (2)

Endogenous Metabolite (11)

Ephrin Receptor (1)

Factor Xa (1)

Ferroptosis (1)

Fungal (1)

GABA Receptor (1)

GLUT (1)

HIV (2)

Influenza Virus (1)

Leukotriene Receptor (1)

Lipoxygenase (1)

Melanocortin Receptor (2)

mGluR (1)

Microtubule/Tubulin (1)

MMP (1)

nAChR (2)

NF-κB (1)

Nucleoside Antimetabolite/Analog (2)

Opioid Receptor (2)

p38 MAPK (1)

Parasite (1)

Phosphatase (1)

PI3K (1)

PI4K (1)

PKA (1)

PKC (1)

Potassium Channel (1)

PROTAC Linker (10)

Reactive Oxygen Species (1)

Reverse Transcriptase (1)

SARS-CoV (1)

Sodium Channel (1)

Thrombin (1)

TNF Receptor (1)

TRP Channel (1)

Tyrosinase (2)

VD/VDR (6)

Virus Protease (1)

By Research Areas:

Cancer (72)

Cardiovascular Disease (23)

Endocrinology (12)

Infection (14)

Inflammation/Immunology (43)

Metabolic Disease (22)

Neurological Disease (17)

179

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

113

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas

HY-N1064

Xanthoplanine	nAChR	Neurological Disease
Xanthoplanine, isolated from theroot of Xylopia parviflora, fully inhibits the EC₅₀ ACh responses of both alpha7 and alpha4beta2 nACh receptors with estimated IC₅₀ values of 9 μM (alpha7) and 5 μM (alpha4beta2).

HY-130119

Integrin-IN-2	Integrin	Cancer
Integrin-IN-2 (compound 39) is an orally bioavailable pan αv integrin inhibitor. Integrin-IN-2 can increases the αvβ6, αvβ3, αvβ5 and αvβ8 binding affinities with pIC₅₀ values of 7.8, 8.4, 8.4 and 7.4, respectively.

HY-18668

Integrin Antagonists 27
Integrin Cancer

Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist with binding affinity of 18 nM, as s novel anticancer agent.

Integrin Antagonists 27	Integrin	Cancer
Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist with binding affinity of 18 nM, as s novel anticancer agent.

HY-100445

αvβ1 integrin-IN-1	Integrin	Cancer Cardiovascular Disease
αvβ1 integrin-IN-1 (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC₅₀ of 0.63 nM. Antifibrotic effects.

HY-12149

A-867744	nAChR Autophagy	Neurological Disease
A-867744 is a highly potent and selective type II positive allosteric modulator (PAM) of the alpha7 nicotinic acetylcholine receptors (nAChR) with an EC₅₀ of 1.0 μM.

HY-100445A

*αvβ1 integrin-IN-1* TFA**	Integrin	Cancer Cardiovascular Disease
αvβ1 integrin-IN-1 TFA (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC₅₀ of 0.63 nM. Antifibrotic effects.

HY-P1868

*α2β1 Integrin* Ligand Peptide**	Integrin	Infection
α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors.

HY-P1868A

*α2β1 Integrin* Ligand Peptide TFA**	Integrin	Others
α2β1 Integrin Ligand Peptide TFA interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors.

HY-129453

BOP sodium	Integrin	Inflammation/Immunology
BOP sodium is a potent and selective dual **α9β1/α4β1 integrin inhibitor with K_d** values in the picomolar range. BOP sodium shows the rapid and preferential mobilization of hematopoietic stem cell (HSC) and progenitors. BOP sodium has little inhibitory activity on α4β7, α1β1, α2β1, and α5β1, αIIBβ3 integrins.

HY-P0178

LXW7	Integrin	Inflammation/Immunology
LXW7, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor. LXW7 has a high binding affinity to αvβ3 integrin with an IC₅₀ of 0.68 μM. LXW7 increases phosphorylation of VEGFR-2 and activation of ERK1/2. Anti-inflammatory effect.

HY-B0381A

Betaxolol hydrochloride SL75212	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Betaxolol Hydrochloride is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma.

HY-B0381

Betaxolol	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Betaxolol is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma.

HY-P0023

Cyclo(-RGDfK)	Integrin	Cancer
Cyclo(-RGDfK) is a potent and selective inhibitor of the α_vβ₃ integrin, with an IC₅₀ of 0.94 nM. Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface.

HY-P0178A

LXW7 TFA	Integrin	Inflammation/Immunology
LXW7 TFA, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor. LXW7 has a high binding affinity to αvβ3 integrin with an IC₅₀ of 0.68 μM. LXW7 TFA increases phosphorylation of VEGFR-2 and activation of ERK1/2. Anti-inflammatory effect.

HY-P0023A

Cyclo(-RGDfK) TFA	Integrin	Cancer
Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the α_vβ₃ integrin, with an IC₅₀ of 0.94 nM. Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface.

HY-P9911

Vedolizumab Anti-Human lymphocyte α4β7 integrin, Humanized Antibody	Integrin	Inflammation/Immunology
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 *integrin* for the treatment of ulcerative colitis and Crohn's disease.

HY-A0275

Amezinium methylsulfate Amezinium metilsulfate; Lu-1631	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Amezinium metilsulfate has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition ofnoradrenaline and tyramine uptake.

HY-B1154

Penbutolol sulfate (-)-Terbuclomine	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Penbutolol sulfate is able to bind to both beta-1 adrenergic receptors and beta-2 adrenergic receptors (the two subtypes), thus making it a non-selective β blocker.

HY-U00439

Protein kinase inhibitors 1
DYRK Cancer

Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC₅₀ of 74 nM and K_d of 9.5 nM.

*Protein kinase inhibitors* 1**	DYRK	Cancer
Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC₅₀ of 74 nM and K_d of 9.5 nM.

HY-W008859

Tetrac Tetraiodothyroacetic acid; 3,3',5,5'-Tetraiodothyroacetic acid	Others	Cancer
Tetrac is a naturally occurring metabolite of L-Thyroxine (T4). Tetrac can specifically block the binding and thyroid hormone action at the integrin receptor, and has anticancer and anti-angiogenic activity.

HY-100607A

Landiolol hydrochloride ONO1101 hydrochloride	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Landiolol hydrochloride (ONO1101 hydrochloride) is a highly beta1 selective ultra-short acting beta-blocker (β1/β2 selectivity = 255:1, a half-life of 4 min)， acts as an adrenoceptor antagonist.

HY-N6712

Thiolutin Acetopyrrothin	Bacterial Antibiotic	Infection Metabolic Disease
Thiolutin (Acetopyrrothin) is a disulfide-containing antibiotic and anti-angiogenic compound produced by Streptomyces. Thiolutin inhibits the JAMM metalloproteases Csn5, Associated-molecule-with-the-SH3-Domain-of-STAM (AMSH) and Brcc36. Thiolutin is a potent and selective inhibitor of endothelial cell adhesion accompanied by rapid induction of Heat-shock protein beta-1 (Hsp27) phosphorylation.

HY-100506

GLPG0187
Integrin Cancer

GLPG0187 is a broad spectrum integrin receptor antagonist with antitumor activity; inhibits α_vβ₁-integrin with an IC₅₀ of 1.3 nM.
HY-70073

Zaurategrast
CT7758
Integrin Inflammation/Immunology

Zaurategrast (CT7758) is a potent and oral-effective α₄-integrin inhibitor.
HY-P0290A

GRGDSP TFA
Integrin Cancer

GRGDSP (TFA) is an integrin inhibitor.
HY-111413

c(phg-isoDGR-(NMe)k)
Integrin Cancer

c(phg-isoDGR-(NMe)k) is a selective and potent α5β1-integrin ligand with an IC₅₀ of 2.9 nM.
HY-111413A

c(phg-isoDGR-(NMe)k) TFA
Integrin Cancer

c(phg-isoDGR-(NMe)k) TFA is a selective and potent α5β1-integrin ligand with an IC₅₀ of 2.9 nM.
HY-P0290

GRGDSP
Integrin Cancer

GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.

GLPG0187	Integrin	Cancer
GLPG0187 is a broad spectrum *integrin* receptor antagonist with antitumor activity; inhibits α_vβ₁-integrin with an IC₅₀ of 1.3 nM.

Zaurategrast CT7758	Integrin	Inflammation/Immunology
Zaurategrast (CT7758) is a potent and oral-effective *α₄-integrin* inhibitor.

GRGDSP TFA	Integrin	Cancer
GRGDSP (TFA) is an *integrin* inhibitor.

c(phg-isoDGR-(NMe)k)	Integrin	Cancer
c(phg-isoDGR-(NMe)k) is a selective and potent *α5β1-integrin* ligand with an IC₅₀ of 2.9 nM.

c(phg-isoDGR-(NMe)k) TFA	Integrin	Cancer
c(phg-isoDGR-(NMe)k) TFA is a selective and potent *α5β1-integrin* ligand with an IC₅₀ of 2.9 nM.

GRGDSP	Integrin	Cancer
GRGDSP, a synthetic linear RGD peptide, is an *integrin* inhibitor.

HY-13306

Pyrintegrin	Integrin	Metabolic Disease
Pyrintegrin is an *β1-integrin* agonist and a 2,4-disubstituted pyrimidine that promotes embryonic stem cells survival. Pyrintegrin enhances cell-extracellular matrix (ECM) adhesion-mediated *integrin* signaling. Pyrintegrin can be used as a podocyte-protective agent and has robustly adipogenic.

HY-17369

Tirofiban hydrochloride monohydrate	Integrin	Cardiovascular Disease
Tirofiban hydrochloride monohydrate is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist IC50 value: Target: integrin IIb/IIIa Tirofiban hydrochloride monohydrate blocks platelet aggregation and thrombus formation.

HY-N1163

Tetrahydroalstonine	Adrenergic Receptor	Endocrinology Neurological Disease
Tetrahydroalstonine, a indole alkaloid isolated from the fruits of Rhazya stricta, is a selective alpha 2-adrenoceptor antagonist.

HY-12290

Arg-Gly-Asp-Ser RGDS peptide; Fibronectin tetrapeptide	Integrin	Inflammation/Immunology
Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function, decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9.

HY-17369B

Tirofiban L700462; MK383	Integrin	Cardiovascular Disease
Tirofiban(L700462;MK383) is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist Target: integrin IIb/IIIa Tirofiban hydrochloride monohydrate blocks platelet aggregation and thrombus formation.

HY-115677

ILK-IN-3
Integrin Cancer

ILK-IN-3 is an integrin linked kinase inhibitor with antitumor activity.
HY-100563

Cyclo(RGDyK) trifluoroacetate
Integrin Cancer

Cyclo(RGDyK) trifluoroacetate is a potent and selective α_Vβ₃ integrin inhibitor with an IC₅₀ of 20 nM.
HY-100563A

Cyclo(RGDyK)
Integrin Cancer

Cyclo(RGDyK) is a potent and selective α_Vβ₃ integrin inhibitor with an IC₅₀ of 20 nM.
HY-14857

Carotegrast
Integrin Inflammation/Immunology

Carotegrast is an orally available α4 integrin receptor inhibitor with anti-inflammatories activities.
HY-131005

Ehp inhibitor 2
Ephrin Receptor Cancer

Ehp inhibitor 2 is a Eph family tyrosine kinase inhibitor.
HY-12799

6-Alpha Naloxol
Alpha-Naloxol
Opioid Receptor Neurological Disease

6-Alpha Naloxol(Alpha-Naloxol) is an opioid antagonist closely related to naloxone; a human metabolite of naloxone.
HY-14571

E7820
ER68203-00
Integrin Cancer

E7820 is an angiogenesis inhibitor by suppressing integrin a2, a cell adhesion molecule expressed on endothelial cells.

ILK-IN-3	Integrin	Cancer
ILK-IN-3 is an integrin linked kinase inhibitor with antitumor activity.

Cyclo(RGDyK) trifluoroacetate	Integrin	Cancer
Cyclo(RGDyK) trifluoroacetate is a potent and selective α_Vβ₃ integrin inhibitor with an IC₅₀ of 20 nM.

Cyclo(RGDyK)	Integrin	Cancer
Cyclo(RGDyK) is a potent and selective α_Vβ₃ integrin inhibitor with an IC₅₀ of 20 nM.

Carotegrast	Integrin	Inflammation/Immunology
Carotegrast is an orally available *α4 integrin* receptor** inhibitor with anti-inflammatories activities.

Ehp inhibitor 2	Ephrin Receptor	Cancer
Ehp inhibitor 2 is a Eph family tyrosine kinase inhibitor.

*6-Alpha* Naloxol** Alpha-Naloxol	Opioid Receptor	Neurological Disease
6-Alpha Naloxol(Alpha-Naloxol) is an opioid antagonist closely related to naloxone; a human metabolite of naloxone.

E7820 ER68203-00	Integrin	Cancer
E7820 is an angiogenesis inhibitor by suppressing integrin a2, a cell adhesion molecule expressed on endothelial cells.

HY-16143

Cilengitide TFA EMD 121974 TFA	Integrin Autophagy	Cancer
Cilengitide is a potent and selective *integrin* inhibitor for α_vβ₃ and α_vβ₅ receptor, with IC₅₀ values of 4 nM and 79 nM, respectively.

HY-P1613A

Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA
Integrin Cancer

Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) is an inhibitor of integrin αvβ3, with antitumor activity.

Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA	Integrin	Cancer
Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) is an inhibitor of integrin αvβ3, with antitumor activity.

HY-125833

Alpha-Naphthoflavone	Aromatase	Cancer
Alpha-Naphthoflavone is a synthetic flavonoid, acts as a potent and competitive aromatase inhibitor with an IC₅₀ and a K_i of 0.5 and 0.2 μM, respectively.

HY-N1917

Alpha-Solamarine
Others Metabolic Disease

Alpha-Solamarine is a glycoalkaloid isolated from Solanum aculeastrum.

Alpha-Solamarine	Others	Metabolic Disease
Alpha-Solamarine is a glycoalkaloid isolated from Solanum aculeastrum.

HY-121222

alpha-Bisabolol	Apoptosis	Cancer
alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC₅₀=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells.

HY-12290A

Arg-Gly-Asp-Ser (TFA) RGDS peptide (TFA); Fibronectin tetrapeptide (TFA)	Integrin	Inflammation/Immunology
Arg-Gly-Asp-Ser (TFA) is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser (TFA) directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1.

HY-121879

SHP836
Phosphatase Cancer

SHP836 is a SHP2 allosteric inhibitor, with an IC₅₀ of 12 μM for the full length SHP2.

SHP836	Phosphatase	Cancer
SHP836 is a SHP2 allosteric inhibitor, with an IC₅₀ of 12 μM for the full length SHP2.

HY-N1501

Beta-asarone	Others	Inflammation/Immunology Neurological Disease
Beta-asarone is a major ingredient of Acorus tatarinowii Schott, penetrates blood brain barrier, with the properties of immunosuppression, central nervous system inhibition, sedation, and hypothermy. Beta-asarone protects against Parkinson’s disease.

HY-N2188

Beta-Acetoxyisovalerylshikonin
Others Inflammation/Immunology

Beta-Acetoxyisovalerylshikonin is a naphthoquinone derivative isolated from Arnebia euchroma.

HY-N6018

Beta-Eudesmol	TRP Channel	Metabolic Disease
Beta-Eudesmol is a natural oxygenated sesquiterpene, activates *hTRPA1, with an EC₅₀* of 32.5 μM. Beta-Eudesmol increases appetite through TRPA1.

HY-113418

Beta-Cortol
Endogenous Metabolite Endocrinology

Beta-Cortol is an androgen metabolite present in adults.

HY-N6740

Beta-Zearalanol	Apoptosis	Metabolic Disease
Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells. Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid.

HY-P2267

LDV
Integrin

LDV, a non-fluorescent derivative of LDV FITC, is a α4β1 integrin (VLA-4) ligand (K_d ~ 12 nM).
HY-14951

Firategrast
SB 683699
Integrin Neurological Disease

Firategrast is an orally bioavailable α4β1/α4β7 integrin antagonist.
HY-13535

ATN-161
Integrin Cancer

ATN-161 is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model.

HY-13535A

ATN-161 trifluoroacetate salt ATN-161 TFA salt	Integrin	Cancer
ATN-161 trifluoroacetate salt is a novel **integrin α5β1** antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model.

HY-P0278

RGD
Integrin Cancer

RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.
HY-P0031

Cyclo(RADfK)
Integrin Others

Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.

HY-P0278A

RGD Trifluoroacetate	Integrin	Cancer
RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; RGD Trifluoroacetate binds to *integrins*.

HY-16141

Cilengitide EMD 121974	Integrin Autophagy	Cancer
Cilengitide, a cyclic RGD-containing peptide, is a potent and selective *integrin* inhibitor for α_vβ₃ and α_vβ₅ receptor, with IC₅₀s of 4 and 79 nM, respectively.

HY-128417

alpha-D-glucose
Endogenous Metabolite Metabolic Disease

alpha-D-glucose is an endogenous metabolite.

HY-125648

Euphorbadienol Alpha-Euphorbol	Others	Infection
Euphorbadienol (alpha-Euphorbol), a triterpenic compound, isolated from the latex of Euphorbia resinifera. The derivatives of Euphorbadienol can be used as elicitors of disease resistance, and has antileishmanial and antitrypanosomal activity.

HY-B1761

Santonin
Alpha-Santonin
Parasite Infection

Santonin is an active principle of the plant Artemisia cina, which is formely used to treat worms.

HY-19373

RWJ-445167 3DP-10017	Thrombin Factor Xa	Cardiovascular Disease
RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with K_i of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity.

HY-16787

ICA-121431	Sodium Channel	Cardiovascular Disease
ICA-121431 is a nanomolar potent and broad-spectrum voltage-gated sodium channel (Na_v) blocker, shows equipotent selectivity for human Na_v1.1 and Na_v1.3 subtypes with IC₅₀ values of 13 nM and 23 nM, respectively. ICA-121431 shows less potent inhibition of Na_v1.2 (IC₅₀=240 nM) and 1,000 fold selectivity against Na_v1.4, Na_v1.6, and the TTX-resistant human Na_v1.5 and Na_v1.8 channels (IC₅₀s >10 µM).

HY-N1484

7beta-Hydroxylathyrol
Others Others

7beta-Hydroxylathyrol is a natural product.

HY-107589A

BIO5192 hydrate	Integrin	Inflammation/Immunology
BIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor (K_d<10 pM). BIO5192 hydrate selectively binds to α4β1 (IC₅₀=1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels.

HY-107589

BIO5192	Integrin	Inflammation/Immunology
BIO5192 is a selective and potent integrin *α4β1* (VLA-4) inhibitor (K_d<10 pM). BIO5192 selectively binds to α4β1 (IC₅₀=1.8 nM) over a range of other integrins. BIO5192 results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels.

HY-108831

Natalizumab	Integrin	Inflammation/Immunology
Natalizumab is a recombinant, humanized monoclonal antibody, binds to α4β1-integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1). Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses.

HY-15701

Leukadherin-1
Complement System Integrin Inflammation/Immunology

Leukadherin-1 is a specific agonist of complement receptor 3 (CR3) and the leukocyte surface αMβ2 integrin CD11b/CD18.
HY-P1187

HSDVHK-NH2
Integrin Cancer

HSDVHK-NH2 is an antagonist of the integrin αvβ3-vitronectin interaction, with an IC₅₀ of 1.74 pg/mL (2.414 pM).

HY-U00439A

*Protein kinase inhibitors* 1 hydrochloride** (E)-5-((2-Oxo-6'-(piperazin-1-yl)-1,2-dihydro-[3,3'-bipyridin]-5-yl)methylene)thiazolidine-2,4-dione hydrochloride	DYRK	Cancer
Protein kinase inhibitors 1 hydrochloride is a potent HIPK2 inhibitor, with IC₅₀s of 136 and 74 nM for HIPK1 and HIPK2, and a K_d of 9.5 nM for HIPK2.

HY-P1187A

HSDVHK-NH2 TFA
Integrin Cancer

HSDVHK-NH2 TFA is an antagonist of the integrin αvβ3-vitronectin interaction, with an IC₅₀ of 1.74 pg/mL (2.414 pM).

HY-N0255

alpha-Hederin α-Hederin	Apoptosis	Others
alpha-Hederin (α-Hederin) is a water-soluble pentacyclic triterpenoid saponin, possessing several biological properties such as antispasmodic, moliscicidic, anthelmithic and inhibiting cell proliferation，

HY-N0328

alpha-Mangostin α-Mangostin	Reactive Oxygen Species Apoptosis Bacterial Fungal Virus Protease	Cancer
alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a K_i of 2.85 μM.

HY-100371

(RS)-MCPG Alpha-MCPG	mGluR	Neurological Disease
(RS)-MCPG (alpha-MCPG) is a competitive and selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. (RS)-MCPG blocks theta-burst stimulation (TBS)-induced shifts in both juvenile and neonatal rat hippocampal neurons.

HY-P2291

Beta-defensin 103 isoform X1, pig	Bacterial	Inflammation/Immunology
Beta-defensin 103 isoform X1, pig is an antimicrobial peptide found in different living organisms, involved in the first line of defense in their innate immune response against pathogens.

HY-W012037

8-Hydroxyquinoline hemisulfate 8-Quinolinol hemisulfate	Bacterial Antibiotic	Infection
8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.

HY-15770

TR-14035
Integrin Inflammation/Immunology

TR-14035 is a a dual alpha4beta7(IC50=7 nM)/alpha4beta1 (IC50=87 nM) integrin antagonist .

HY-19344

Lifitegrast SAR 1118; SHP-606	Integrin	Inflammation/Immunology
Lifitegrast (SAR 1118) is an integrin lymphocyte function-associated antigen-1 (LFA-1) antagonist; inhibits Jurkat T cell attachment to *ICAM-1* with an IC₅₀ of 2.98 nM.

HY-P2290

Beta-defensin 1, pig	Bacterial	Infection Inflammation/Immunology
Beta-defensin 1, pig is an antimicrobial peptide found primarily in tongue mucosa of pig. Beta-defensin 1, pig is active against bacteria such as *Escherichia coli, Salmonella typhimurium, Listeria monocytogenes, Staphylococcus aureus, Bordetella pertussis* and Candida albicans.

HY-B1837A

β-Cyfluthrin beta-Cyfluthrin	Calcium Channel	Infection
β-Cyfluthrin (beta-Cyfluthrin) is a type II synthetic pyrethroid and also an active ingredient of many insecticide products used for pestsin agriculture. β-Cyfluthrin is a neurotoxicant and affects calcium concentration in nervous tissue by inhibiting Ca²⁺ ATPase involved in calcium transport.

HY-19773

*beta-lactamase-IN-1*	Bacterial	Cancer
beta-lactamase-IN-1 targets Neisseria gonorrhoeae infection which comprises administering to a subject in need thereof novel Tricyclic nitrogen containing compounds and corresponding pharmaceutical compositions as described herein.

HY-N0087

Gambogic Acid beta-Guttiferrin	Bcl-2 Family Autophagy	Cancer
Gambogic Acid (Beta-Guttiferrin) is derived from the gamboges resin of the tree Garcinia hanburyi. Gambogic Acid (Beta-Guttiferrin) inhibits Bcl-X_L, Bcl-2, Bcl-W, Bcl-B, *Bfl-1* and *Mcl-1* with IC₅₀s of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM.

HY-N0941

beta-Mangostin
β-Mangostin
Others Others

beta-Mangostin is a natural product.
HY-18644

CWHM-12
Integrin Cancer

CWHM-12 is a potent inhibitor of αV integrins with IC₅₀s of 0.2, 0.8, 1.5, and 1.8 nM for αvβ8, αvβ3, αvβ6, and αvβ1.

HY-P2291A

Beta-defensin 103 isoform X1, pig TFA	Bacterial	Inflammation/Immunology
Beta-defensin 103 isoform X1, pig TFA is an antimicrobial peptide found in different living organisms, involved in the first line of defense in their innate immune response against pathogens.

HY-12836

IFN alpha-IFNAR-IN-1	IFNAR	Inflammation/Immunology
IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM).

HY-B0141A

Alpha-Estradiol Alfatradiol; Epiestradiol; Epiestrol	5 alpha Reductase Endogenous Metabolite	Inflammation/Immunology
Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.

HY-135813

LtaS-IN-1	Bacterial	Infection
LtaS-IN-1 (compound 1771) is a potent small-molecule inhibitor of Lipoteichoic acid (LTA) synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 alone inhibits Enterococcus.spp 28 strains with varying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 combination with antibiotics abolishs multidrug-resistant E. faecium growth almost completely.

HY-125957

A-3 hydrochloride	PKA Casein Kinase CaMK PKC	Others
A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It against PKA (K_i=4.3 µM), casein kinase II (K_i=5.1 µM) and myosin light chain kinase (MLCK) (K_i=7.4 µM). A-3 hydrochloride also inhibits PKC and casein kinase I with K_i values of 47 µM and 80 µM, respectively.

HY-75385

Zaurategrast ethyl ester CDP323; UCB1184197	Integrin	Inflammation/Immunology
Zaurategrast ethyl ester (CDP323), the ethyl ester prodrug of CT7758, is a *α4β1/α4β7* integrin antagonist used for the treatment of inflammatory and autoimmune disorders.

HY-N4180

*Pennogenin 3-O-beta-chacotrioside*	Autophagy	Cancer
Pennogenin 3-O-beta-chacotrioside is an active component isolated from Paris polyphylla, modulates autophagy via increasing the expressions of autophagy-related proteins LC3 and Beclin-1. Anti-colorectal cancer activity.

HY-N2100

*6'-O-beta-D-Glucosylgentiopicroside*	Others	Metabolic Disease
6'-O-beta-D-Glucosylgentiopicroside is a secoiridoid isolated from the roots of G. straminea. 6'-O-beta-D-Glucosylgentiopicroside strongly suppresses N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced superoxide generation.

HY-N3523

*3-O-Beta-D-Glucopyranosylplatycodigenin*	Others	Cancer
3-O-Beta-D-Glucopyranosylplatycodigenin is an oleanane-type triterpenoid isolated from roots of Platycodon grandiflorum. 3-O-Beta-D-Glucopyranosylplatycodigenin exhibits anti-proliferative activities against HSC-T6 cell line with an IC₅₀ of 13.36 μM.

HY-N0406

*2"-O-beta-L-galactopyranosylorientin*	Others	Metabolic Disease
2"-O-beta-L-galactopyranosylorientin is extracted from the flowers of Trollius ledebouri. 2"-O-beta-L-galactopyranosylorientin involves transporter mediated efflux in addition to passive diffusion and is the substrate of multidrug resistance protein 2 (MRP2).

HY-N2075

3-Acetyl-beta-boswellic acid
Others Inflammation/Immunology

3-Acetyl-beta-boswellic acid is a boswellic acid isolated from Boswellia serrata gum resin.

HY-P2290A

Beta-defensin 1, pig TFA	Bacterial	Infection Inflammation/Immunology
Beta-defensin 1, pig TFA is an antimicrobial peptide found primarily in tongue mucosa of pig. Beta-defensin 1, pig TFA is active against bacteria such as *Escherichia coli, Salmonella typhimurium, Listeria monocytogenes, Staphylococcus aureus, Bordetella pertussis* and Candida albicans.

HY-P0295

Gly-Arg-Gly-Asp-Ser	Integrin	Others
Gly-Arg-Gly-Asp-Ser is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC₅₀ of ∼5 and ∼6.5 μM

HY-P0122

iRGD peptide c(CRGDKGPDC)	Integrin	Cancer
iRGD peptide is a 9-amino acid cyclic peptide, triggers tissue penetration of drugs by first binding to av integrins, then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties.

HY-75385A

Zaurategrast ethyl ester sulfate CDP323 sulfate; UCB1184197 sulfate	Integrin	Inflammation/Immunology
Zaurategrast ethyl ester sulfate (CDP323 sulfate), the ethyl ester prodrug of CT7758, is a *α4β1/α4β7* integrin antagonist used for the treatment of inflammatory and autoimmune disorders.

HY-P0295A

Gly-Arg-Gly-Asp-Ser (TFA)	Integrin	Inflammation/Immunology
Gly-Arg-Gly-Asp-Ser (TFA) is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC₅₀ of ∼5 and ∼6.5 μM.

HY-101918

DS-1040 Tosylate	Others	Cardiovascular Disease
DS-1040 Tosylate is an orally active, selective inhibitor of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC₅₀s of 5.92 nM and 8.01 nM for human and rat TAFIa. DS-1040 Tosylate is a fibrinolysis enhancer for thromboembolic diseases.

HY-18728

STF-31
GLUT Autophagy Cancer

STF-31 is a selective inhibitor of glucose transporter 1 (GLUT1), with an IC₅₀ of 1μM^[1][2].

HY-12836A

*IFN alpha-IFNAR-IN-1* hydrochloride**	IFNAR	Inflammation/Immunology
IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM).

HY-N0700

alpha-Asarone α-Asarone; trans-Asarone	GABA Receptor	Neurological Disease
alpha-Asarone (α-Asarone) is one of the main psychoactive compounds, and possesses an antidepressant-like activity in mice.

HY-N0710

alpha-Cyperone α-Cyperone; (+)-α-Cyperone	Endogenous Metabolite	Inflammation/Immunology
alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.

HY-W013636

2-Ketoglutaric acid Alpha-Ketoglutaric acid	Tyrosinase Endogenous Metabolite	Others
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM).

HY-N0611

alpha-Boswellic acid
α-Boswellic acid
Others Inflammation/Immunology

alpha-Boswellic acid is a natural product.

HY-W020044

*DL-alpha-Tocopherol* DL-α-Tocopherol	Ferroptosis	Others
DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB.

HY-32348

Doxercalciferol
1.Alpha.-Hydroxyvitamin D2
VD/VDR Metabolic Disease Cancer

Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor, and prevent renal disease.
HY-141126

Azido-PEG4-alpha-D-mannose
PROTAC Linker Cancer

Azido-PEG4-alpha-D-mannose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-14190

Valategrast R-411 free base	Integrin	Inflammation/Immunology
Valategrast (R-411 free base) is a potent and orally active integrin α4β1 (VLA-4) and *α4β7* dual antagonist. Valategrast has the potential for Chronic obstructive pulmonary disease (COPD) and asthma treatment.

HY-N4099

*Luteolin-3-O-beta-D-glucuronide*	Others	Infection Inflammation/Immunology
Luteolin-3-O-beta-D-glucuronide is a luteolin glucosiduronic acid consisting of luteolin having a beta-D-glucosiduronic acid residue attached at the 3'-position.

HY-P1524

Beta-Amyloid(1-14),mouse,rat
Amyloid-β Neurological Disease

Beta-Amyloid(1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide.

HY-125033

Beta-d-N4-hydroxycytidine NHC	Influenza Virus	Infection
Beta-d-N4-hydroxycytidine (NHC) is a very potent anti-VEEV (venezuelan equine encephalitis virus) agent with EC₅₀, EC₉₀, and EC₉₉ are 0.426, 1.036, and 2.5 μM, respectively.

HY-141131

Propargyl-PEG2-beta-D-glucose
PROTAC Linker Cancer

Propargyl-PEG2-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
HY-141132

Propargyl-PEG4-beta-D-glucose
PROTAC Linker Cancer

Propargyl-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-N0411

β-Carotene Provitamin A; beta-Carotene	Endogenous Metabolite	Metabolic Disease
β-Carotene (Provitamin A) is an organic compound and classified as a terpenoid. It is a precursor (inactive form) of vitamin A.

HY-N2337

11beta-Hydroxyprogesterone 11β-Hydroxyprogesterone	Endogenous Metabolite	Cardiovascular Disease
11beta-Hydroxyprogesterone is a potent inhibitors of 11β-Hydroxysteroid dehydrogenase; also activates human mineralocorticoid receptor in COS-7 cells with an ED₅₀ of 10 nM.

HY-140012

Azido-PEG4-beta-D-glucose
PROTAC Linker Cancer

Azido-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-N2142

*3-O-beta-Allopyranosyl-(1->4)-beta-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin B*	Others	Cancer
3-O-beta-Allopyranosyl-(1->4)-beta-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin B is a chemical constituent of the plant Poria cocos ^[1].

HY-P1740

RGD peptide (GRGDNP)	Integrin Apoptosis	Inflammation/Immunology
RGD peptide (GRGDNP) acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation. RGD peptide (GRGDNP) promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing.

HY-15583

Auristatin F	Microtubule/Tubulin ADC Cytotoxin	Cancer
Auristatin F is a potent cytotoxin. Auristatin F, a potent microtubule inhibitor and vascular damaging agent (VDA), can be used in antibody-drug conjugates (ADC).

HY-P1740A

RGD peptide (GRGDNP) (TFA)	Integrin Apoptosis	Inflammation/Immunology Cancer
RGD peptide (GRGDNP) (TFA) acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation. RGD peptide (GRGDNP) (TFA) promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing.

HY-131089

*MC-VC-PABC-C6-alpha-Amanitin*	Drug-Linker Conjugates for ADC	Cancer
MC-VC-PABC-C6-alpha-Amanitin is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-tumor agent, alpha-Amanitin, linked via the cleavable linker MC-VC-PABC-C6.

HY-P9908

Adalimumab
Anti-Human TNF-Alpha, Human Antibody
TNF Receptor Inflammation/Immunology

Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).
HY-15156

1alpha, 24, 25-Trihydroxy VD2
VD/VDR Metabolic Disease

1alpha, 24, 25-Trihydroxy VD2 is a vitamin D analog.
HY-N6260

4-O-beta-Glucopyranosyl-cis-coumaric acid
Others Others

4-O-beta-Glucopyranosyl-cis-coumaric acid is a natural compound isolated formn Nelumbo nucifera Gaertn.

HY-N2190

*Hederagenin 28-O-beta-D-glucopyranosyl ester*	Others	Inflammation/Immunology Cardiovascular Disease
Hederagenin 28-O-beta-D-glucopyranosyl ester, a triterpenoid saponin isolated from Ilex cornuta, exhibits protective effects against H₂O₂-induced myocardial cell injury.

HY-111642

3'-Azido-3'-deoxy-beta-L-uridine
Nucleoside Antimetabolite/Analog Others

3'-Azido-3'-deoxy-beta-L-uridine (Compound 25) is a nucleoside derivative.

HY-N2587

Irigenin	Integrin	Cancer
Irigenin is a is a lead compound, and mediates its anti-metastatic effect by specifically and selectively blocking *α9β1* and *α4β1* integrins binding sites on C-C loop of Extra Domain A (EDA). Irigenin shows anti-cancer properties. It sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells.

HY-122470

Stampidine	Reverse Transcriptase HIV	Infection
Stampidine is a nucleoside reverse transcriptase inhibitor (NRTI) with potent and broad-spectrum anti-HIV activity. Stampidine inhibits the laboratory HIV-1 strain HTLV_IIIB (B-envelope subtype) and primary clinical isolates with IC₅₀s of 1 nM and 2 nM, respectively. Stampidine also inhibits NRTI-resistant primary clinical isolates and NNRTI-resistant clinical isolates with IC₅₀s of 8.7 nM and 11.2 nM, respectively.

HY-140960

*DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000)*	PROTAC Linker	Cancer
DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-W013636A

2-Ketoglutaric acid Sodium Alpha-Ketoglutaric acid Sodium	Tyrosinase Endogenous Metabolite	Metabolic Disease
2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM).

HY-112716

*N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride*	Others	Cancer
N-alpha-Tosyl-L-lysine chloromethyl ketone (TLCK), a trypsin like protease inhibitor, sensitizes HeLa cells to Fas-mediated cell death.

HY-10003

Alfacalcidol 1-hydroxycholecalciferol; 1.Alpha.-Hydroxyvitamin D3	VD/VDR	Metabolic Disease
Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis.

HY-15327

1alpha, 25-Dihydroxy VD2-D6
VD/VDR Metabolic Disease

1alpha, 25-Dihydroxy VD2-D6 is a deuterated form of vitamin D.

HY-10220

SF1126	PI3K Apoptosis	Cancer
SF1126 is a relevant pan and dual first-in-class PI3K/BRD4 inhibitor, has antitumor and anti-angiogenic activity. SF1126 is an RGDS-conjugated LY294002 prodrug, which is designed to exhibit increased solubility and bind to specific integrins within the tumor compartment. SF1126 induces cell *apoptosis*.

HY-P1521

β-Amyloid 15-21
beta-Amyloid (15-21)
Amyloid-β Neurological Disease

β-amyloid (15-21) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.
HY-141133

Propargyl-PEG4-tetra-Ac-beta-D-glucose
PROTAC Linker Cancer

Propargyl-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
HY-141135

Propargyl-PEG4-tetra-Ac-beta-D-galactose
PROTAC Linker Cancer

Propargyl-PEG4-tetra-Ac-beta-D-galactose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
HY-15679

PI4KIII beta inhibitor 3
PI4K Cancer

PI4KIII beta inhibitor 3 is a novel and high effective PI4KIIIβ inhibitor with IC₅₀ of 5.7 nM.
HY-141127

Azido-PEG4-tetra-Ac-beta-D-glucose
PROTAC Linker Cancer

Azido-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-125773

β-cyano-L-Alanine beta-cyano-l-alanine	Others	Neurological Disease
β-cyano-L-Alanine (Beta-cyano-l-alanine), a nitrile of widespread occurrence in higher plants, is enzymatically produced by cyanoalanine synthase from cyanide and cysteine as substrates. β-cyano-L-Alanine abolishes the protective effect of ethanol on cerebral ischemia/reperfusion (I/R) injury.

HY-15102

MK-0429 L-000845704	Integrin	Inflammation/Immunology Cancer
MK-0429 (L-000845704) is an orally active, potent, selective and nonpeptide *pan-integrin* antagonist with IC₅₀ values of 1.6 nM, 2.8 nM, 0.1 nM, 0.7 nM, 0.5 nM and 12.2 nM for αvβ1, αvβ3, αvβ5, αvβ6, αvβ8 and α5β1, respectively.

HY-11007

GNF-2
Bcr-Abl SARS-CoV Cancer

GNF-2 is a highly selective, allosteric, non-ATP competitive inhibitor of Bcr-Abl. GNF-2 inhibits Ba/F3.p210 proliferation with an IC₅₀ of 138 nM ^[1].

HY-114362

*DL-alpha-Tocopherol methoxypolyethylene glycol succinate* TPGS-750-M	Others	Others
DL-alpha-Tocopherol methoxypolyethylene glycol succinate solution (TPGS-750-M) is an amphiphile, acts as a surfactant.

HY-N5039

1,2-O-Dilinoleoyl-3-O-Beta-D-Galactopyranosylracglycerol
Others Others

1,2-O-Dilinoleoyl-3-O-Beta-D-Galactopyranosylracglycerol is isolated from the flower of Magnolia denudate.
HY-P1522

β-Amyloid 29-40
Amyloid beta-protein(29-40)
Amyloid-β Neurological Disease

β-Amyloid (29-40) is a fragment of Amyloid-β peptide.

HY-141137

*2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide*	PROTAC Linker	Cancer
2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-16686

α-Tocopherol phosphate Alpha-Tocopherol phosphate; TocP; vitamin E phosphate	Others	Others
α-Tocopherol phosphate is the compound demonstrating the highest vitamin E activity, which is available both in its natural form as RRR-alpha-tocopherol isolated from plant sources.

HY-N1968

Quercetin-3-O-β-D-glucose-7-O-β-D-gentiobiosiden Quercetin-3-O-beta-D-glucose-7-O-beta-D-gentiobioside	Others	Others
Quercetin-3-O-β-D-glucose-7-O-β-D-gentiobiosiden is a flavonoid from Quercetin.

HY-125849

Chrysin 7-O-beta-gentiobioside
Chrysin 7-O-β-gentiobioside
Others Cancer

Chrysin 7-O-beta-gentiobioside (Chrysin 7-O-β-gentiobioside) is the glycosylation product of Chrysin.

HY-N6652

1-beta-D-Arabinofuranosyluracil Uracil 1-β-D-arabinofuranoside	Others	Cancer Inflammation/Immunology Cardiovascular Disease
1-beta-D-Arabinofuranosyluracil (Uracil 1-β-D-arabinofuranoside) isolated from the Caribbean sponge Tectitethya crypta, is a methoxyadenosine derivative. 1-beta-D-Arabinofuranosyluracil has demonstrated a diverse bioactivity profile including anti-inflammatory activity, analgesic and vasodilation properties. 1-beta-D-Arabinofuranosyluracil reduces a proliferation of mouse lymphoma cells.

HY-111638

1-(2'-O-4-C-Methylene-beta-D-ribofuranosyl)thymine
Nucleoside Antimetabolite/Analog Infection

1-(2'-O-4-C-Methylene-beta-D-ribofuranosyl)thymine is a bicyclic nucleoside.

HY-N2056

*11-Keto-beta-boswellic acid* 11-Keto-β-boswellic acid	Lipoxygenase Leukotriene Receptor NF-κB	Cancer
11-Keto-beta-boswellic acid (11-Keto-β-boswellic acid) is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense. 11-Keto-beta-boswellic acid has the anti-inflammatory activity is primarily due to inhibit 5-lipoxygenase (5-LOX) and subsequent leukotriene and nuclear factor-kappa B (NF-κB) activation and tumor necrosis factor alpha generation production.

HY-19306

SB-267268	Integrin	Cancer
SB-267268 is a selective and nonpeptidic alpha(v)beta3 (αvβ3) and alpha(v)beta5 (αvβ5) integrins antagonist, with K_is of 0.9, 0.5 and 0.7 nM for human αvβ3, monkey αvβ3 and human αvβ5, respectively. SB-267268 inhibits human and mouse αvβ3 with IC₅₀s of 0.68 and 0.29 nM, respectively. SB-267268 reduces angiogenesis and VEGF expression.

HY-13249

1alpha-Hydroxy VD4 1α-Hydroxy vitamin D4	VD/VDR	Cancer
1alpha-Hydroxy VD4 , a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells.

HY-17552

sn-Glycero-3-phosphocholine Choline Alfoscerate; Alpha-GPC; L-α-GPC	AChE Endogenous Metabolite	Neurological Disease
sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia.

HY-100260

beta-L-D4A
2'3'-didehydro-2'3'-dideoxyadenosine
HIV Infection

beta-L-D4A is a nucleoside HIV-1 reverse transcriptase inhibitor.

HY-P1504

β-Melanocyte Stimulating Hormone (MSH), human beta-MSH (1-22) (human)	Melanocortin Receptor	Metabolic Disease Neurological Disease Endocrinology
β-Melanocyte Stimulating Hormone (MSH), human, a 22-residue peptide, acts as an endogenous melanocortin-4 receptor (MC4-R) agonist.

HY-114464

*11-Beta-hydroxyandrostenedione* 4-Androsten-11β-ol-3,17-dione	Endogenous Metabolite	Endocrinology
11-Beta-hydroxyandrostenedione (4-Androsten-11β-ol-3,17-dione) is a steroid mainly found in the the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue). 11-Beta-hydroxyandrostenedione is a 11β-hydroxysteroid dehydrogenase (11βHSD) isozymes inhibitor. As 4-androstenedione increases, measuring plasma 11-Beta-hydroxyandrostenedione can distinguish the adrenal or ovarian origin of hyperandrogenism.

HY-N7035

*Wogonin 7-O-beta-D-glucuronide methyl ester* Wogonoside methyl ester	Others	Metabolic Disease
Wogonin 7-O-beta-D-glucuronide methyl ester is a natural compound isolated from Huanglian Jiedutang.

HY-15589

GW9508	GPR40 Potassium Channel	Metabolic Disease Inflammation/Immunology Cardiovascular Disease
GW9508 is a potent and selective G protein-coupled receptors FFA1 (GPR40) and GPR120 agonist with pEC₅₀s of 7.32 and 5.46, respectively. GW9508 shows ~100-fold selectivity for GPR40 over GPR120. GW9508 is inactive against other GPCRs, kinases, proteases, integrins and PPARs. GW9508 is a glucose-sensitive insulin secretagogue and an ATP-sensitive potassium (K_ATP) channels opener. Anti-inflammatory and anti-atherosclerotic activities.

HY-141139

1-(Isopropylthio)-2,3,4,6-tetra-o-Ac-beta-D-glucosylpyranose	PROTAC Linker	Cancer
1-(Isopropylthio)-2,3,4,6-tetra-o-Ac-beta-D-glucosylpyranose is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-12780S

*6-beta-Naloxol D5 hydrochloride* 6β-Naloxol D5 hydrochloride	Opioid Receptor	Neurological Disease
6-beta-Naloxol D5 hydrochloride is the deuterium labeled 6-beta-Naloxol, which is an opioid antagonist closely related to naloxone.

HY-N0171A

Beta-Sitosterol (purity>98%) β-Sitosterol (purity>98%); 22,23-Dihydrostigmasterol (purity>98%)	Apoptosis	Cancer Inflammation/Immunology Cardiovascular Disease
Beta-Sitosterol (purity>98%) is a plant sterol. Beta-Sitosterol (purity>98%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation.

HY-P1504A

β-Melanocyte Stimulating Hormone (MSH), human TFA beta-MSH (1-22) (human) TFA	Melanocortin Receptor	Metabolic Disease Neurological Disease Endocrinology
β-Melanocyte Stimulating Hormone (MSH), human TFA, a 22-residue peptide, acts as an endogenous melanocortin-4 receptor (MC4-R) agonist.

HY-N0171B

Beta-Sitosterol (purity>75%) β-Sitosterol (purity>75%); 22,23-Dihydrostigmasterol (purity>75%)	Apoptosis	Cancer Inflammation/Immunology Cardiovascular Disease
Beta-Sitosterol (purity>75%) includes 75% β-sitosterol and 10% campesterol. Beta-Sitosterol is a plant sterol. Beta-Sitosterol (purity>75%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation.

HY-N0171

Beta-Sitosterol (purity>80%) β-Sitosterol (purity>80%); 22,23-Dihydrostigmasterol (purity>80%)	Endogenous Metabolite Apoptosis	Cancer Inflammation/Immunology Cardiovascular Disease
Beta-Sitosterol (purity>80%) includes β-sitosterol (≥80%), stigmasterol, campesterol and brassicasterol mainly. Beta-Sitosterol is a plant sterol. Beta-Sitosterol (purity>98%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation.

HY-18676

OSU-T315	Integrin Autophagy Apoptosis	Cancer
OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC₅₀ of 0.6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain). OSU-T315 abrogates AKT activation by impeding AKT localization in lipid rafts and triggers caspase-dependent apoptosis in an ILK-independent manner. OSU-T315 causes cell death through apoptosis and *autophagy*.

HY-13331

Clascoterone Cortexolone 17 Alpha-propionate; Cortexolone 17α-propionate; CB-03-01	Androgen Receptor	Endocrinology
Clascoterone (Cortexolone 17 alpha-propionate;Cortexolone 17α-propionate;CB-03-01) is a new topical and peripherally selective androgen antagonist.

HY-32337

Tacalcitol 1,24(R)-Dihydroxyvitamin D3; 1.Alpha.,24R-Dihydroxyvitamin D3	VD/VDR	Metabolic Disease
Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium.

HY-122872

MKK7-COV-9	p38 MAPK	Cancer
MKK7-COV-9 is a potent and selective covalent inhibitor of *MKK7* and targets a specific protein–protein interaction of MKK7. MKK7-COV-9 blocks primary B cell activation in response to LPS with an EC₅₀ of 4.98 μM.

HY-P0128

β-Amyloid (25-35) Amyloid beta-peptide (25-35); Aβ25-35; β-Amyloid peptide (25-35)	Amyloid-β	Neurological Disease
β-Amyloid (25-35) (Amyloid beta-peptide (25-35)) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, has shown neurotoxic activities in cultured cells.

HY-N6006

1,3,6-Tri-O-galloyl-beta-D-glucose 1,3,6-Tri-O-galloyl-β-D-glucose	Others	Others
1,3,6-Tri-O-galloyl-beta-D-glucose (1,3,6-Tri-O-galloyl-β-D-glucose) is a phenolic compound in Black Walnut Kernels.

HY-120944

BAY-7598	MMP	Inflammation/Immunology
BAY-7598 is a potent, orally bioavailable, and selective MMP12 inhibitor probe with IC₅₀s of 0.085, 0.67 and 1.1 nM for human MMP12, murine MMP12, and rat MMP12, respectively.

HY-104004

Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH Fmoc-Ser-(GalNAc(Ac)3-Alpha-D)-OH; Fmoc-Ser[GalNAc(Ac)3-α-D]-OH; Fmoc-Ser(Ac3AcNH-α-Gal)-OH	Others	Cancer
Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH is a drug for cancer.

Cat. No.	Product Name	Type

HY-111413

c(phg-isoDGR-(NMe)k)
Biochemical Assay Reagents

c(phg-isoDGR-(NMe)k) is a selective and potent α5β1-integrin ligand with an IC₅₀ of 2.9 nM.
HY-111413A

c(phg-isoDGR-(NMe)k) TFA
Biochemical Assay Reagents

c(phg-isoDGR-(NMe)k) TFA is a selective and potent α5β1-integrin ligand with an IC₅₀ of 2.9 nM.

HY-18593

6-O-α-Maltosyl-β-cyclodextrin 6-O-Alpha-D-Maltosyl-beta-cyclodextrin	Biochemical Assay Reagents
6-O-α-Maltosyl-β-cyclodextrin is a cellular cholesterol modifier which can form soluble inclusion complex with cholesterol.

HY-101461

Methyl-β-cyclodextrin Methyl-beta-cyclodextrin	Biochemical Assay Reagents
Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin) is a water-soluble cyclic heptasaccharide used to deliver hydrophobic drugs based on its property of solubilizing non-polar substances. Methyl-β-cyclodextrin is also extensively used as a cholesterol-depleting reagent.

HY-W039911

4-Nitrophenyl α-D-galactopyranoside PNP-Alpha-D-Gal; PNP-α-D-Gal	Enzyme Substrates
4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates.

Cat. No.	Product Name	Target	Research Area

HY-P1868

*α2β1 Integrin* Ligand Peptide**	Integrin	Infection
α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors.

HY-P1868A

*α2β1 Integrin* Ligand Peptide TFA**	Integrin	Others
α2β1 Integrin Ligand Peptide TFA interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors.

HY-P0178

LXW7	Integrin	Inflammation/Immunology
LXW7, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor. LXW7 has a high binding affinity to αvβ3 integrin with an IC₅₀ of 0.68 μM. LXW7 increases phosphorylation of VEGFR-2 and activation of ERK1/2. Anti-inflammatory effect.

HY-P0178A

LXW7 TFA	Integrin	Inflammation/Immunology
LXW7 TFA, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor. LXW7 has a high binding affinity to αvβ3 integrin with an IC₅₀ of 0.68 μM. LXW7 TFA increases phosphorylation of VEGFR-2 and activation of ERK1/2. Anti-inflammatory effect.

HY-P0322

GRGDSPK EMD 56574	Peptides	Metabolic Disease Cardiovascular Disease
GRGDSPK (EMD 56574) is a peptide incluing Arg-Gly-Asp (RGD). GRGDSPK (EMD 56574) is an competitive and reversible inhibitory peptide for inhibiting integrin-fibronectin binding. GRGDSPK is used to study the role of integrins in bone formation and resorption.

HY-P0322A

GRGDSPK TFA EMD 56574 TFA	Peptides	Metabolic Disease Cardiovascular Disease
GRGDSPK TFA (EMD 56574 TFA) is a peptide incluing Arg-Gly-Asp (RGD). GRGDSPK TFA is an competitive and reversible inhibitory peptide for inhibiting integrin-fibronectin binding. GRGDSPK TFA is used to study the role of integrins in bone formation and resorption.

HY-P1897

Fibronectin Active Fragment Control	Peptides	Inflammation/Immunology
Fibronectin Active Fragment Control is an active peptide fragment of fibronectin. Fibronectin is a glycoprotein interacting with integrins.

HY-P0290A

GRGDSP TFA
Integrin Cancer

GRGDSP (TFA) is an integrin inhibitor.
HY-P0290

GRGDSP
Integrin Cancer

GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.
HY-100563A

Cyclo(RGDyK)
Integrin Cancer

Cyclo(RGDyK) is a potent and selective α_Vβ₃ integrin inhibitor with an IC₅₀ of 20 nM.

HY-12290A

Arg-Gly-Asp-Ser (TFA) RGDS peptide (TFA); Fibronectin tetrapeptide (TFA)	Integrin	Inflammation/Immunology
Arg-Gly-Asp-Ser (TFA) is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser (TFA) directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1.

HY-P2267

LDV
Integrin

LDV, a non-fluorescent derivative of LDV FITC, is a α4β1 integrin (VLA-4) ligand (K_d ~ 12 nM).
HY-P0278

RGD
Integrin Cancer

RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.
HY-P0031

Cyclo(RADfK)
Integrin Others

Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.

HY-P0278A

RGD Trifluoroacetate	Integrin	Cancer
RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; RGD Trifluoroacetate binds to *integrins*.

HY-P1187

HSDVHK-NH2
Integrin Cancer

HSDVHK-NH2 is an antagonist of the integrin αvβ3-vitronectin interaction, with an IC₅₀ of 1.74 pg/mL (2.414 pM).
HY-P1187A

HSDVHK-NH2 TFA
Integrin Cancer

HSDVHK-NH2 TFA is an antagonist of the integrin αvβ3-vitronectin interaction, with an IC₅₀ of 1.74 pg/mL (2.414 pM).

HY-P2291

Beta-defensin 103 isoform X1, pig	Bacterial	Inflammation/Immunology
Beta-defensin 103 isoform X1, pig is an antimicrobial peptide found in different living organisms, involved in the first line of defense in their innate immune response against pathogens.

HY-P2290

Beta-defensin 1, pig	Bacterial	Infection Inflammation/Immunology
Beta-defensin 1, pig is an antimicrobial peptide found primarily in tongue mucosa of pig. Beta-defensin 1, pig is active against bacteria such as *Escherichia coli, Salmonella typhimurium, Listeria monocytogenes, Staphylococcus aureus, Bordetella pertussis* and Candida albicans.

HY-P2291A

Beta-defensin 103 isoform X1, pig TFA	Bacterial	Inflammation/Immunology
Beta-defensin 103 isoform X1, pig TFA is an antimicrobial peptide found in different living organisms, involved in the first line of defense in their innate immune response against pathogens.

HY-P1888

*HIF-1 alpha* (556-574)**	Peptides	Cardiovascular Disease
HIF-1 alpha (556-574) is a short hypoxia-inducible factor-1 (HIF-1) 19 residues fragment. HIF-1 functions as master regulator of response to oxygen homeostasis.

HY-P1901

*Insulin alpha-chain (1-13)*	Peptides	Metabolic Disease
Insulin alpha-chain (1-13) is a human leucocyte antigen (HLA)-DR4-restricted epitope comprising the first 13 amino acids of the insulin A-chain.

HY-P2290A

Beta-defensin 1, pig TFA	Bacterial	Infection Inflammation/Immunology
Beta-defensin 1, pig TFA is an antimicrobial peptide found primarily in tongue mucosa of pig. Beta-defensin 1, pig TFA is active against bacteria such as *Escherichia coli, Salmonella typhimurium, Listeria monocytogenes, Staphylococcus aureus, Bordetella pertussis* and Candida albicans.

HY-P0295

Gly-Arg-Gly-Asp-Ser	Integrin	Others
Gly-Arg-Gly-Asp-Ser is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC₅₀ of ∼5 and ∼6.5 μM

HY-P0122

iRGD peptide c(CRGDKGPDC)	Integrin	Cancer
iRGD peptide is a 9-amino acid cyclic peptide, triggers tissue penetration of drugs by first binding to av integrins, then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties.

HY-P0295A

Gly-Arg-Gly-Asp-Ser (TFA)	Integrin	Inflammation/Immunology
Gly-Arg-Gly-Asp-Ser (TFA) is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC₅₀ of ∼5 and ∼6.5 μM.

HY-P1888A

*HIF-1 alpha* (556-574) (TFA)**	Peptides	Cardiovascular Disease
HIF-1 alpha (556-574) TFA is a short hypoxia-inducible factor-1 (HIF-1) 19 residues fragment. HIF-1 functions as master regulator of response to oxygen homeostasis.

HY-P1524

Beta-Amyloid(1-14),mouse,rat
Amyloid-β Neurological Disease

Beta-Amyloid(1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide.

HY-P1740

RGD peptide (GRGDNP)	Integrin Apoptosis	Inflammation/Immunology
RGD peptide (GRGDNP) acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation. RGD peptide (GRGDNP) promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing.

HY-P1740A

RGD peptide (GRGDNP) (TFA)	Integrin Apoptosis	Inflammation/Immunology Cancer
RGD peptide (GRGDNP) (TFA) acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation. RGD peptide (GRGDNP) (TFA) promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing.

HY-P1912

Alpha 1(I) Collagen (614-639), human
Peptides Endocrinology

Alpha 1(I) Collagen (614-639), human is a peptide fragment of alpha-1 type I collagen.
HY-P1521

β-Amyloid 15-21
beta-Amyloid (15-21)
Amyloid-β Neurological Disease

β-amyloid (15-21) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.
HY-P1522

β-Amyloid 29-40
Amyloid beta-protein(29-40)
Amyloid-β Neurological Disease

β-Amyloid (29-40) is a fragment of Amyloid-β peptide.

HY-P1504

β-Melanocyte Stimulating Hormone (MSH), human beta-MSH (1-22) (human)	Melanocortin Receptor	Metabolic Disease Neurological Disease Endocrinology
β-Melanocyte Stimulating Hormone (MSH), human, a 22-residue peptide, acts as an endogenous melanocortin-4 receptor (MC4-R) agonist.

HY-P1504A

β-Melanocyte Stimulating Hormone (MSH), human TFA beta-MSH (1-22) (human) TFA	Melanocortin Receptor	Metabolic Disease Neurological Disease Endocrinology
β-Melanocyte Stimulating Hormone (MSH), human TFA, a 22-residue peptide, acts as an endogenous melanocortin-4 receptor (MC4-R) agonist.

Cat. No.	Product Name	Target	Research Area

HY-P9911

Vedolizumab Anti-Human lymphocyte α4β7 integrin, Humanized Antibody	Integrin	Inflammation/Immunology
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 *integrin* for the treatment of ulcerative colitis and Crohn's disease.

HY-108831

Natalizumab	Integrin	Inflammation/Immunology
Natalizumab is a recombinant, humanized monoclonal antibody, binds to α4β1-integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1). Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses.

HY-P9908

Adalimumab
Anti-Human TNF-Alpha, Human Antibody
TNF Receptor Inflammation/Immunology

Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).

Cat. No.	Product Name	Target	Category

HY-N1064

Xanthoplanine	nAChR	Alkaloids
Xanthoplanine, isolated from theroot of Xylopia parviflora, fully inhibits the EC₅₀ ACh responses of both alpha7 and alpha4beta2 nACh receptors with estimated IC₅₀ values of 9 μM (alpha7) and 5 μM (alpha4beta2).

HY-W008859

Tetrac Tetraiodothyroacetic acid; 3,3',5,5'-Tetraiodothyroacetic acid	Others	Acids and Aldehydes
Tetrac is a naturally occurring metabolite of L-Thyroxine (T4). Tetrac can specifically block the binding and thyroid hormone action at the integrin receptor, and has anticancer and anti-angiogenic activity.

HY-100607A

Landiolol hydrochloride ONO1101 hydrochloride	Adrenergic Receptor	Natural Products
Landiolol hydrochloride (ONO1101 hydrochloride) is a highly beta1 selective ultra-short acting beta-blocker (β1/β2 selectivity = 255:1, a half-life of 4 min)， acts as an adrenoceptor antagonist.

HY-N6712

Thiolutin Acetopyrrothin	Bacterial Antibiotic	Natural Products
Thiolutin (Acetopyrrothin) is a disulfide-containing antibiotic and anti-angiogenic compound produced by Streptomyces. Thiolutin inhibits the JAMM metalloproteases Csn5, Associated-molecule-with-the-SH3-Domain-of-STAM (AMSH) and Brcc36. Thiolutin is a potent and selective inhibitor of endothelial cell adhesion accompanied by rapid induction of Heat-shock protein beta-1 (Hsp27) phosphorylation.

HY-N1163

Tetrahydroalstonine
Adrenergic Receptor Alkaloids

Tetrahydroalstonine, a indole alkaloid isolated from the fruits of Rhazya stricta, is a selective alpha 2-adrenoceptor antagonist.
HY-N1917

Alpha-Solamarine
Others Alkaloids Saccharides and Glycosides

Alpha-Solamarine is a glycoalkaloid isolated from Solanum aculeastrum.

HY-121222

alpha-Bisabolol	Apoptosis	Terpenoids and Glycosides
alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC₅₀=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells.

HY-N1501

Beta-asarone	Others	Phenylpropanoids
Beta-asarone is a major ingredient of Acorus tatarinowii Schott, penetrates blood brain barrier, with the properties of immunosuppression, central nervous system inhibition, sedation, and hypothermy. Beta-asarone protects against Parkinson’s disease.

HY-N2188

Beta-Acetoxyisovalerylshikonin
Others Natural Products

Beta-Acetoxyisovalerylshikonin is a naphthoquinone derivative isolated from Arnebia euchroma.

HY-N6018

Beta-Eudesmol	TRP Channel	Terpenoids and Glycosides
Beta-Eudesmol is a natural oxygenated sesquiterpene, activates *hTRPA1, with an EC₅₀* of 32.5 μM. Beta-Eudesmol increases appetite through TRPA1.

HY-N6740

Beta-Zearalanol	Apoptosis	Natural Products
Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells. Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid.

HY-128417

alpha-D-glucose
Endogenous Metabolite Saccharides and Glycosides

alpha-D-glucose is an endogenous metabolite.

HY-125648

Euphorbadienol Alpha-Euphorbol	Others	Terpenoids and Glycosides
Euphorbadienol (alpha-Euphorbol), a triterpenic compound, isolated from the latex of Euphorbia resinifera. The derivatives of Euphorbadienol can be used as elicitors of disease resistance, and has antileishmanial and antitrypanosomal activity.

HY-B1761

Santonin
Alpha-Santonin
Parasite Terpenoids and Glycosides

Santonin is an active principle of the plant Artemisia cina, which is formely used to treat worms.
HY-N1484

7beta-Hydroxylathyrol
Others Terpenoids and Glycosides

7beta-Hydroxylathyrol is a natural product.

HY-N0255

alpha-Hederin α-Hederin	Apoptosis	Saccharides and Glycosides Terpenoids and Glycosides
alpha-Hederin (α-Hederin) is a water-soluble pentacyclic triterpenoid saponin, possessing several biological properties such as antispasmodic, moliscicidic, anthelmithic and inhibiting cell proliferation，

HY-N0328

alpha-Mangostin α-Mangostin	Reactive Oxygen Species Apoptosis Bacterial Fungal Virus Protease	Natural Products
alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a K_i of 2.85 μM.

HY-N0087

Gambogic Acid beta-Guttiferrin	Bcl-2 Family Autophagy	Natural Products
Gambogic Acid (Beta-Guttiferrin) is derived from the gamboges resin of the tree Garcinia hanburyi. Gambogic Acid (Beta-Guttiferrin) inhibits Bcl-X_L, Bcl-2, Bcl-W, Bcl-B, *Bfl-1* and *Mcl-1* with IC₅₀s of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM.

HY-N0941

beta-Mangostin
β-Mangostin
Others Flavonoids

beta-Mangostin is a natural product.

HY-B0141A

Alpha-Estradiol Alfatradiol; Epiestradiol; Epiestrol	5 alpha Reductase Endogenous Metabolite	Steroids
Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.

HY-N4180

*Pennogenin 3-O-beta-chacotrioside*	Autophagy	Saccharides and Glycosides
Pennogenin 3-O-beta-chacotrioside is an active component isolated from Paris polyphylla, modulates autophagy via increasing the expressions of autophagy-related proteins LC3 and Beclin-1. Anti-colorectal cancer activity.

HY-N2100

*6'-O-beta-D-Glucosylgentiopicroside*	Others	Saccharides and Glycosides Terpenoids and Glycosides
6'-O-beta-D-Glucosylgentiopicroside is a secoiridoid isolated from the roots of G. straminea. 6'-O-beta-D-Glucosylgentiopicroside strongly suppresses N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced superoxide generation.

HY-N3523

*3-O-Beta-D-Glucopyranosylplatycodigenin*	Others	Saccharides and Glycosides Terpenoids and Glycosides
3-O-Beta-D-Glucopyranosylplatycodigenin is an oleanane-type triterpenoid isolated from roots of Platycodon grandiflorum. 3-O-Beta-D-Glucopyranosylplatycodigenin exhibits anti-proliferative activities against HSC-T6 cell line with an IC₅₀ of 13.36 μM.

HY-N0406

*2"-O-beta-L-galactopyranosylorientin*	Others	Flavonoids
2"-O-beta-L-galactopyranosylorientin is extracted from the flowers of Trollius ledebouri. 2"-O-beta-L-galactopyranosylorientin involves transporter mediated efflux in addition to passive diffusion and is the substrate of multidrug resistance protein 2 (MRP2).

HY-N2075

3-Acetyl-beta-boswellic acid
Others Terpenoids and Glycosides

3-Acetyl-beta-boswellic acid is a boswellic acid isolated from Boswellia serrata gum resin.

HY-N0700

alpha-Asarone α-Asarone; trans-Asarone	GABA Receptor	Phenylpropanoids
alpha-Asarone (α-Asarone) is one of the main psychoactive compounds, and possesses an antidepressant-like activity in mice.

HY-N0710

alpha-Cyperone α-Cyperone; (+)-α-Cyperone	Endogenous Metabolite	Terpenoids and Glycosides
alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.

HY-W013636

2-Ketoglutaric acid Alpha-Ketoglutaric acid	Tyrosinase Endogenous Metabolite	Acids and Aldehydes
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM).

HY-N0611

alpha-Boswellic acid
α-Boswellic acid
Others Terpenoids and Glycosides

alpha-Boswellic acid is a natural product.

HY-W020044

*DL-alpha-Tocopherol* DL-α-Tocopherol	Ferroptosis	Phenols
DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB.

HY-N4099

*Luteolin-3-O-beta-D-glucuronide*	Others	Flavonoids Saccharides and Glycosides
Luteolin-3-O-beta-D-glucuronide is a luteolin glucosiduronic acid consisting of luteolin having a beta-D-glucosiduronic acid residue attached at the 3'-position.

HY-N0411

β-Carotene Provitamin A; beta-Carotene	Endogenous Metabolite	Terpenoids and Glycosides
β-Carotene (Provitamin A) is an organic compound and classified as a terpenoid. It is a precursor (inactive form) of vitamin A.

HY-N2337

11beta-Hydroxyprogesterone 11β-Hydroxyprogesterone	Endogenous Metabolite	Steroids
11beta-Hydroxyprogesterone is a potent inhibitors of 11β-Hydroxysteroid dehydrogenase; also activates human mineralocorticoid receptor in COS-7 cells with an ED₅₀ of 10 nM.

HY-N2142

*3-O-beta-Allopyranosyl-(1->4)-beta-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin B*	Others	Steroids
3-O-beta-Allopyranosyl-(1->4)-beta-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin B is a chemical constituent of the plant Poria cocos ^[1].

HY-N6260

*4-O-beta-Glucopyranosyl-cis-coumaric acid*	Others	Phenylpropanoids Saccharides and Glycosides
4-O-beta-Glucopyranosyl-cis-coumaric acid is a natural compound isolated formn Nelumbo nucifera Gaertn.

HY-N2190

*Hederagenin 28-O-beta-D-glucopyranosyl ester*	Others	Saccharides and Glycosides Terpenoids and Glycosides
Hederagenin 28-O-beta-D-glucopyranosyl ester, a triterpenoid saponin isolated from Ilex cornuta, exhibits protective effects against H₂O₂-induced myocardial cell injury.

HY-N2587

Irigenin	Integrin	Flavonoids
Irigenin is a is a lead compound, and mediates its anti-metastatic effect by specifically and selectively blocking *α9β1* and *α4β1* integrins binding sites on C-C loop of Extra Domain A (EDA). Irigenin shows anti-cancer properties. It sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells.

HY-W013636A

2-Ketoglutaric acid Sodium Alpha-Ketoglutaric acid Sodium	Tyrosinase Endogenous Metabolite	Acids and Aldehydes
2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM).

HY-N5039

1,2-O-Dilinoleoyl-3-O-Beta-D-Galactopyranosylracglycerol	Others	Natural Products
1,2-O-Dilinoleoyl-3-O-Beta-D-Galactopyranosylracglycerol is isolated from the flower of Magnolia denudate.

HY-N1968

Quercetin-3-O-β-D-glucose-7-O-β-D-gentiobiosiden Quercetin-3-O-beta-D-glucose-7-O-beta-D-gentiobioside	Others	Flavonoids
Quercetin-3-O-β-D-glucose-7-O-β-D-gentiobiosiden is a flavonoid from Quercetin.

HY-N6652

1-beta-D-Arabinofuranosyluracil Uracil 1-β-D-arabinofuranoside	Others	Saccharides and Glycosides
1-beta-D-Arabinofuranosyluracil (Uracil 1-β-D-arabinofuranoside) isolated from the Caribbean sponge Tectitethya crypta, is a methoxyadenosine derivative. 1-beta-D-Arabinofuranosyluracil has demonstrated a diverse bioactivity profile including anti-inflammatory activity, analgesic and vasodilation properties. 1-beta-D-Arabinofuranosyluracil reduces a proliferation of mouse lymphoma cells.

HY-N2056

*11-Keto-beta-boswellic acid* 11-Keto-β-boswellic acid	Lipoxygenase Leukotriene Receptor NF-κB	Terpenoids and Glycosides
11-Keto-beta-boswellic acid (11-Keto-β-boswellic acid) is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense. 11-Keto-beta-boswellic acid has the anti-inflammatory activity is primarily due to inhibit 5-lipoxygenase (5-LOX) and subsequent leukotriene and nuclear factor-kappa B (NF-κB) activation and tumor necrosis factor alpha generation production.

HY-17552

sn-Glycero-3-phosphocholine Choline Alfoscerate; Alpha-GPC; L-α-GPC	AChE Endogenous Metabolite	Natural Products
sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia.

HY-N7035

*Wogonin 7-O-beta-D-glucuronide methyl ester* Wogonoside methyl ester	Others	Saccharides and Glycosides
Wogonin 7-O-beta-D-glucuronide methyl ester is a natural compound isolated from Huanglian Jiedutang.

HY-N0171A

Beta-Sitosterol (purity>98%) β-Sitosterol (purity>98%); 22,23-Dihydrostigmasterol (purity>98%)	Apoptosis	Steroids
Beta-Sitosterol (purity>98%) is a plant sterol. Beta-Sitosterol (purity>98%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation.

HY-N0171B

Beta-Sitosterol (purity>75%) β-Sitosterol (purity>75%); 22,23-Dihydrostigmasterol (purity>75%)	Apoptosis	Steroids
Beta-Sitosterol (purity>75%) includes 75% β-sitosterol and 10% campesterol. Beta-Sitosterol is a plant sterol. Beta-Sitosterol (purity>75%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation.

HY-N0171

Beta-Sitosterol (purity>80%) β-Sitosterol (purity>80%); 22,23-Dihydrostigmasterol (purity>80%)	Endogenous Metabolite Apoptosis	Steroids
Beta-Sitosterol (purity>80%) includes β-sitosterol (≥80%), stigmasterol, campesterol and brassicasterol mainly. Beta-Sitosterol is a plant sterol. Beta-Sitosterol (purity>98%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation.

HY-N6006

1,3,6-Tri-O-galloyl-beta-D-glucose 1,3,6-Tri-O-galloyl-β-D-glucose	Others	Phenols
1,3,6-Tri-O-galloyl-beta-D-glucose (1,3,6-Tri-O-galloyl-β-D-glucose) is a phenolic compound in Black Walnut Kernels.

Cat. No.	Product Name	Species	Source

HY-P7117

*Recombinant Mouse TGF-beta* 1/TGFB1 (HEK293-expressed)** rMuTGF-beta 1/TGFB1; Transforming growth factor beta-1; TGF-β1; LAP	Mouse	HEK 293
Recombinant Mouse TGF-beta 1/TGFB1 (HEK293-expressed) is a multifunctional cytokine that controls numerous biological processes including immunity, differentiation, tumor suppression, tumor metastasis, senescence, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis.

HY-P7365

Recombinant Human Heregulin-1 beta1 rHuHeregulin-1 β1; ARIA; HRG; NRG1; Neuregulin-1	Human	E. coli
Recombinant Human Heregulin-1 beta1 belongs to a family of structurally-related polypeptide growth factors derived from alternatively spliced genes, induces Fn14 expression in MCF7 cells.

HY-P7118

Recombinant Human Transforming Growth Factor β1 TGF-beta-1; TGFB1; TGFB; rHuTGF-β1	Human	CHO
TGFβ1 is a multifunctional cytokine which participates in foetal development, control of cell growth and differentiation, induces fibrosis, causes the suppression of immune response, is involved in angiogenesis, the development of tumours, and inflammatory processes.

HY-P7304

Recombinant Human Tumor Necrosis Factor beta rHuTNF-β; TNF-β; TNFSF1; Lymphotoxin-Alpha	Human	E. coli
Recombinant Human Tumor Necrosis Factor beta exhibits anti-proliferative activity and causes the cellular destruction of tumor cell lines and performs a variety of important roles in immune regulation.

HY-P7544

Recombinant Mouse Interferon -alpha2
Interferon Alpha 2; IFNA2 Protein, Mouse
E. coli

HY-P7137

*Recombinant Human Beta* Defensin-3** rHuBD-3; DEFB-3; HBD3; beta-defensin 103	Human	E. coli
Recombinant Human Beta Defensin-3 is an antibacterial peptide that exhibits antibacterial activities towards Gram-negative and Gram-positive bacteria as well as an ability to act as a chemo-attractant.

HY-P7138

*Recombinant Mouse Beta* Defensin-3** rMuBD-3; DEFB-3; HBD3; beta-defensin 103	Mouse	E. coli
Recombinant Mouse Beta Defensin-3 is an inducible antimicrobial peptide and exhibits broad-spectrum antimicrobial activity.

HY-P7139

*Recombinant Rat Beta* Defensin-3** rRtBD-3; DEFB-3; HBD3; beta-defensin 103	Rat	E. coli
Recombinant Rat Beta Defensin-3 is an inducible antimicrobial peptide and exhibits broad-spectrum antimicrobial activity.

HY-P7589

Recombinant Human beta-NGF Protein (CHO-expressed)
rHubeta-NGF Protein; beta-nerve growth factor; beta-NGF; NGF; NGFB
Human CHO

HY-P7140

*Recombinant Human Beta* Defensin-4** rHuBD-4; DEFB-4; beta-defensin 104; DEFB4; DEFB104	Human	E. coli
Recombinant Human Beta Defensin-4 is an inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity.

HY-P7141

*Recombinant Rat Beta* Defensin-4** rRtBD-4; DEFB-4; beta-defensin 104; DEFB4; DEFB104	Rat	E. coli
Recombinant Rat Beta Defensin-4 is an inducible peptide with a broad spectrum antimicrobial activity.

HY-P7542

Recombinant Human Serpin A1/alpha-1-Antitrypsin, His (HEK293-expressed) rHuSerpin A1/Alpha-1-Antitrypsin, His; Alpha-1-Antitrypsin; Alpha-1 Protease Inhibitor; Alpha-1-Antiproteinase; Serpin A1; SERPINA1; AAT; PI	Human	HEK 293
Recombinant Human Serpin A1/alpha-1-Antitrypsin, His (HEK293-expressed) produced in HEK293 cells is a mouse recombinant Serpin A1a with a His tag at the C-terminus^[1]. Alpha-1 Antitrypsin Exerts a hepatoprotective effect on immune-mediated hepatitis and acetaminophen-induced liver injury^[2].

HY-P7493

*Recombinant Human alpha-Parvin, His* rHuAlpha-Parvin, His; PARVA; MXRA2; Alpha-Parvin	Human	E. coli
Recombinant Human alpha-Parvin, His is a recombinant human alpha-Parvin with a His tag at the C-terminus. Alpha-parvin is an essential regulator of actin-dependent processes, such as cell spreading and migration^[1].

HY-P7463

*Recombinant Human Alpha-Fetoprotein, His (HEK293-expressed)* rHuAlpha-Fetoprotein, His; AFP; Alpha-Fetoprotein	Human	HEK 293
Recombinant Human Alpha-Fetoprotein, His (HEK293-expressed) is a major plasma protein produced by the yolk sac and the fetal liver during fetal development.

HY-P7464

*Recombinant Mouse Alpha-Fetoprotein, His (HEK293-expressed)* rMuAlpha-Fetoprotein, His; AFP; Alpha-Fetoprotein	Mouse	HEK 293
Recombinant Mouse Alpha-Fetoprotein, His (HEK293-expressed) is a mouse recombinant AFP with a His tag at the C-terminus. Recombinant Mouse Alpha-Fetoprotein, His is produced by Mammalian expression system and the target gene encoding Lys19-Val605 is expressed.

HY-P7190

*Recombinant Human GRO beta/CXCL2* rHuGRO-β/CXCL2; C-X-C motif chemokine 2; MIP2-Alpha; HSF	Human	E. coli
Recombinant Human GRO beta/CXCL2 is a powerful neutrophil chemoattractant and is involved in many immune responses including wound healing, cancer metastasis, and angiogenesis.

HY-P7558

*Recombinant Human Transforming Growth Factor beta3 (CHO-expressed)* rHuTGF-β3; Transforming growth factor beta-3 proprotein; Latency-associated peptide; LAP; Transforming growth factor beta-3; TGF-beta-3; TGFB3	Human	CHO

HY-P7548

*Recombinant Human Interleukin-1 alpha* (CHO-expressed)** rHuIL-1α; Interleukin-1 Alpha; IL-1 Alpha; Hematopoietin-1; IL1A; IL1F1	Human	CHO
Recombinant Human Interleukin-1 alpha (CHO-expressed) is a CHO cell derived polypeptidic cytokine that play a key role in inflammation and immunologic reactions.

HY-P7187

Recombinant Human GRO alpha/CXCL1 rHuGRO-α/CXCL1; NAP-3; MGSA; Growth-regulated Alpha protein	Human	E. coli
Recombinant Human GRO alpha/CXCL1 could play a major role in inflammation, angiogenesis, tumorigenesis, and wound healing.

HY-P7489

Recombinant Human Alpha 1-Microglobulin, His (HEK293-expressed)
rHuAlpha 1-Microglobulin, His; AMBP; Alpha 1-Microglobulin
Human HEK 293

HY-P7492

*Recombinant Human alpha-Galactosidase A, His (HEK293-expressed)* rHuAlpha-Galactosidase A, His; GLA; Alpha-Galactosidase A	Human	HEK 293
Recombinant Human alpha-Galactosidase A, His (HEK293-expressed), a recombinant human alpha-Galactosidase A produced in HEK293 cells, has a His tag at the C-terminus. Recombinant Human alpha-Galactosidase A is the lysosomal exoglycosidase responsible for the hydrolysis of terminal α-galactosyl residues from glycoconjugates and is the defective enzyme causing Fabry disease^[1].

HY-P7362

Recombinant Human Glia Maturation Factor beta rHuGMFB; GMFB	Human	E. coli
Recombinant Human Glia Maturation Factor beta is a major component of glia maturation factor family, essential in brain development and responses to stress.

HY-P7428

*Recombinant Mouse Transforming growth factor-beta* receptor type 2, His (HEK293-expressed)** TGFR-2; TGF-beta type II receptor; TGF-beta receptor type 2; TbetaR-II	Mouse	HEK 293
Recombinant Mouse Transforming growth factor-beta receptor type 2, His consists of N-terminal ectodomain and C-terminal protein kinase domain with his tag. TGF-beta receptor type-2 is the ligand-binding receptor for all members of the TGF-β family.

HY-P7557

*Recombinant Human Transforming Growth Factor beta2 (CHO-expressed)* rHuTGF-β2; Transforming growth factor beta-2 proprotein; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; Latency-associated peptide; LAP; Transforming growth factor beta-2; TGF-beta-2; TGFB2	Human	CHO

HY-P7028

Recombinant Human Interleukin-1 beta rHuIL-1β; Catabolin; IL1F2; IL-1 beta; IL1B	Human	E. coli
Recombinant Human Interleukin-1 beta is a polypeptidic cytokine that play a key role in inflammation and immunologic reactions.

HY-P7073

Recombinant Mouse Interleukin-1 beta rMuIL-1β; Catabolin; IL1F2; IL-1 beta; IL1B	Mouse	E. coli
Recombinant Mouse Interleukin-1 beta is a proinflammatory, cell-associated cytokine, produced by monocytes, tissue macrophages, keratinocytes and other epithelial cells.

HY-P7097

Recombinant Rat Interleukin-1 beta rRtIL-1β; Catabolin; IL1F2; IL-1 beta; IL1B	Rat	E. coli
Recombinant Rat Interleukin-1 beta is an immunomodulary cytokine that mediates a wide range of immune responses.

HY-P7426

*Recombinant Human Transforming growth factor-beta* receptor type 2, C-Fc (HEK293-expressed)** TGFR-2; TGF-beta type II receptor; TGF-beta receptor type 2; TbetaR-II	Human	HEK 293
Recombinant Human Transforming growth factor-beta receptor type 2, C-Fc, a fragment of transforming growth factor-beta receptor type 2 (TβRII), consists of amino acid of Thr23-Asp159 with an Fc tag at the C-terminus.

HY-P7427

*Recombinant Mouse Transforming growth factor-beta* receptor type 2, C-Fc (HEK293-expressed)** TGFR-2; TGF-beta type II receptor; TGF-beta receptor type 2; TbetaR-II	Mouse	HEK 293
Recombinant Mouse Transforming growth factor-beta receptor type 2, C-Fc, a fragment of transforming growth factor-beta receptor type 2 (TβRII), consists of amino acid of Ile24-Asp159 with a 6His tag at the C-terminus.

HY-P7027

Recombinant Human Interleukin-1 alpha rHuIL-1α; Hematopoietin-1; IL1A; IL1F1; IL-1 Alpha	Human	E. coli
Recombinant Human Interleukin-1 alpha is a polypeptidic cytokine that play a key role in inflammation and immunologic reactions.

HY-P7090

*Recombinant Mouse Tumor Necrosis Factor-alpha/TNFSF2* rMuTNF-α/TNFSF2; TNF-Alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor	Mouse	E. coli
Recombinant Mouse Tumor Necrosis Factor-alpha/TNFSF2 is a strong pro-inflammatory cytokine, effective in the immune system during inflammation, cell proliferation, differentiation and apoptosis.

HY-P7072

Recombinant Mouse Interleukin-1 alpha rMuIL-1α; Hematopoietin-1; IL1A; IL1F1; IL-1 Alpha	Mouse	E. coli
Recombinant Murine Interleukin-1 alpha, a potent immuno-modulator that mediates a wide range of immune and inflammatory responses.

HY-P7058

*Recombinant Human Tumor Necrosis Factor-alpha/TNFSF2* rHuTNF-α/TNFSF2; TNF-Alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor	Human	E. coli
Recombinant Human Tumor Necrosis Factor-alpha/TNFSF2 is a strong pro-inflammatory cytokine, exhibits high efficacy and tumor cell targeting capability, with low toxicity effects on healthy cells.

HY-P7135

Recombinant Human beta Defensin-2
rHuBD-2; DEFB2
Human E. coli

Recombinant Human beta Defensin-2 is an anti-microbial peptide that participates in the response to microbial invasion.
HY-P7136

Recombinant Mouse Beta Defensin-2
rMuBD-2; DEFB2
Mouse E. coli

Recombinant Mouse beta Defensin-2 is an anti-microbial peptide that participates in the response to microbial invasion.

HY-P7152

Recombinant Rat CXCL3 (CHO-expressed) rRtCXCL3; C-X-C motif chemokine 3; Cytokine-induced neutrophil chemoattractant 2; CINC-2; MIP2-Alpha/beta	Rat	CHO
Recombinant Rat CXCL3 (CHO-expressed) acts as a chemoattractant for neutrophils and is involved in the inflammatory response.

HY-P7073A

*Recombinant Mouse Interleukin-1 beta* (CHO-expressed)** rMuIL-1β; Catabolin; IL1F2; IL-1 beta; IL1B	Mouse	CHO
Recombinant Mouse Interleukin-1 beta (CHO-expressed) is a CHO cell derived proinflammatory, cell-associated cytokine, produced by monocytes, tissue macrophages, keratinocytes and other epithelial cells.

HY-P7563

*Recombinant Human Interleukin-2 Receptor alpha/CD25 (CHO-expressed)* rHuIL-2R α/CD25; Interleukin-2 receptor subunit Alpha; IL-2 receptor subunit Alpha; IL-2-RA; IL-2R subunit Alpha; IL2-RA; TAC antigen; p55; CD25; IL2RA	Human	CHO

HY-P7096

*Recombinant Rat Interleukin-1 alpha* (CHO-expressed)** rRtIL-1α; Hematopoietin-1; IL1A; IL1F1; IL-1 Alpha	Rat	CHO
Recombinant Rat Interleukin-1 alpha (CHO-expressed) is a nonsecreted pro-inflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells and endothelial cells.

HY-P7500

Recombinant Human Alpha-amylase 2B, His (HEK293-expressed)
rHuAlpha-amylase 2B, His; AMY2B; Alpha-amylase 2B
Human HEK 293

HY-P7097A

*Recombinant Rat Interleukin-1 beta* (HEK293-expressed)** rRtIL-1β; Catabolin; IL1F2; IL-1 beta; IL1B	Rat	HEK 293
Recombinant Rat Interleukin-1 beta (HEK293-expressed) is a HEK293 cell derived immunomodulary cytokine that mediates a wide range of immune responses.

HY-P7559

Recombinant Human Interleukin-4 Receptor (CHO-expressed) rHuIL-4R; Interleukin-4 receptor subunit Alpha; IL-4 receptor subunit Alpha; IL-4R subunit Alpha; IL-4R-Alpha; IL-4RA; CD124; IL-4 receptor subunit Alpha; IL-4R-alph; sIL4RAlpha/prot; IL-4-binding protein; IL4-BP; IL4R; IL4RA	Human	CHO
Recombinant Human Interleukin-4 Receptor (CHO-expressed) is a CHO cell derived type I transmembrane protein that can bind interleukin-4 and interleukin-13^[1].

HY-P7024

*Recombinant Human Interferon-beta* (HEK293-expressed)** rHuIFN-β; IFNB	Human	HEK 293
Recombinant Human Interferon-beta1b is a cytokine with immunomodulatory properties.Recombinant Human Interferon-beta1b can be used for the study of severe COVID-19 (coronavirus disease), it reduce viral load and improve lung pathology in a marmoset model^[3].

HY-P7090A

*Recombinant Mouse Tumor Necrosis Factor-alpha/TNFSF2 (P.pastoris-expressed)* rMuTNF-α/TNFSF2; TNF-Alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor	Mouse	P. pastoris
Recombinant Mouse Tumor Necrosis Factor-alpha/TNFSF2 (P.pastoris-expressed) is a strong pro-inflammatory cytokine, effective in the immune system during inflammation, cell proliferation, differentiation and apoptosis.

HY-P7108

*Recombinant Rat Tumor Necrosis Factor-alpha/TNFSF2 (P.pastoris-expressed)* rRtTNF-α/TNFSF2; TNF-Alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor	Rat	P. pastoris
Recombinant Rat Tumor Necrosis Factor-alpha/TNFSF2 (P.pastoris-expressed) is a strong pro-inflammatory cytokine, effective in the immune system during inflammation, cell proliferation, differentiation and apoptosis.

HY-P7058A

*Recombinant Human Tumor Necrosis Factor-alpha/TNFSF2 (P.pastoris-expressed)* rHuTNF-α/TNFSF2; TNF-Alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor	Human	P. pastoris
Recombinant Human Tumor Necrosis Factor-alpha/TNFSF2 (P.pastoris-expressed) is a strong pro-inflammatory cytokine, exhibits high efficacy and tumor cell targeting capability, with low toxicity effects on healthy cells.

HY-P7188

Recombinant Mouse GRO alpha/CXCL1 rMuGRO-α/CXCL1; Growth-regulated Alpha protein; C-X-C motif chemokine 1; KC; HSF	Mouse	E. coli
Recombinant Mouse GRO alpha/CXCL1 could play a major role in inflammation, angiogenesis, tumorigenesis, and wound healing.

HY-P7189

Recombinant Rat GRO alpha/CXCL1 rRtGRO-α/CXCL1; Growth-regulated Alpha protein; C-X-C motif chemokine 1; CINC-1	Rat	E. coli
Recombinant Rat GRO alpha/CXCL1 could play a major role in inflammation, angiogenesis, tumorigenesis, and wound healing.

HY-P7133

*Recombinant Human Beta* Defensin-1** rHuBD-1; HBD1; DEFB1	Human	E. coli
Recombinant Human Beta Defensin-1 is an antimicrobial peptide that defends epithelial surfaces including the skin, gastrointestinal, and respiratory tracts.

HY-P7134

*Recombinant Rat Beta* Defensin-1** rRtBD-1; HBD1; DEFB1	Rat	E. coli
Recombinant Rat Beta Defensin-1 is antimicrobial peptide that defends epithelial surfaces including the skin, gastrointestinal, and respiratory tracts.

HY-P7206

Recombinant Porcine Interleukin-1 beta rPoIL-1β; IL1B	Porcine	E. coli
Recombinant Porcine Interleukin-1 beta could regulate the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.

HY-P7186

*Recombinant Mouse GRO alpha/CXCL1* (CHO-expressed)** rMuGRO-α/CXCL1; Growth-regulated Alpha protein; C-X-C motif chemokine 1; KC; HSF	Mouse	CHO
Recombinant Mouse GRO alpha/CXCL1 (CHO expressed) could play a major role in inflammation, angiogenesis, tumorigenesis, and wound healing.

HY-P7491

*Recombinant Mouse Alpha-1-antitrypsin 1-1, His (HEK293-expressed)* rMuAlpha-1-antitrypsin 1-1, His; Serpin A1a; Alpha-1-antitrypsin 1-1	Mouse	HEK 293
Recombinant Mouse Alpha-1-antitrypsin 1-1, His (HEK293-expressed) is a mouse recombinant Serpin A1a with a His tag at the C-terminus. Recombinant Mouse Alpha-1-antitrypsin 1-1, His is produced by Mammalian expression system and the target gene encoding Glu25-Lys413 is expressed.

HY-P7009

Recombinant Human Endostatin (P.pastoris-expressed) rHuEndostatin; Collagen Alpha-1(XV) chain	Human	P. pastoris
Recombinant Human Endostatin (P.pastoris-expressed) is an endogenous antiangiogenic peptide with multiple antitumor roles through modulation of various receptors in the plasma membrane, such as suppression of angiogenesis and inhibition of tumor-cell migration and invasion.

HY-P7296

*Recombinant Human Transforming Growth Factor alpha* (CHO-expressed)** rHuTGF-α; ETGF; TGFA	Human	CHO
Recombinant Human Transforming Growth Factor alpha (CHO-expressed) is a potent angiogenic mediator and mitogenic polypeptide.

HY-P7302

Recombinant Bovine Tumor Necrosis Factor alpha rBoTNF-α; Cachectin; TNFA; TNF-α	Bovine	E. coli
Recombinant Bovine Tumor Necrosis Factor alpha is a cytokine involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction.

HY-P7411

Recombinant Human Transforming Growth Factor alpha rHuTGF-α; ETGF; TGF-type I	Human	E. coli
Recombinant Human Transforming Growth Factor alpha (TGF-α) is a 50-amino-acid polypeptide that binds to the epidermal growth factor (EGF) receptor and stimulates cell growth.

HY-P7207

Recombinant Rhesus Macaque Interleukin-1 beta rRhIL-1β; IL1B	Rhesus Macaque	E. coli
Recombinant Rhesus Macaque Interleukin-1 beta could regulate the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.

HY-P7490

Recombinant Human alpha-1-acid glycoprotein 2, His (HEK293-expressed)
rHuAlpha-1-acid glycoprotein 2, His; AGP2; ORM2; Alpha-1-acid glycoprotein 2
Human HEK 293

HY-P7303

Recombinant Rhesus Macaque Tumor Necrosis Factor alpha rRhTNF-α; Cachectin; TNF-α; TNFA	Rhesus Macaque	E. coli
Recombinant Rhesus Macaque Tumor Necrosis Factor alpha is a cytokine involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction.

HY-P7416

*Recombinant Human Tumor Necrosis Factor alpha, His* rHuTNF-α, His; Cachectin; TNFSF2	Human	E. coli
Recombinant Human Tumor Necrosis Factor alpha, His is recombinant human tumor necrosis factor alpha (TNF-α) with his tag. Recombinant Human Tumor Necrosis Factor alpha, a pleiotropic cytokine, is one of the major mediators of inflammation and is involved in a number of infectious and parasitic diseases. It appears to be involved in blood-brain barrier, inflammatory, thrombogenic, and vascular changes associated with brain injury.

HY-P7417

*Recombinant Mouse Tumor Necrosis Factor alpha, His* rMuTNF-α, His; Cachectin; TNFSF2	Mouse	E. coli
Recombinant Mouse Tumor Necrosis Factor alpha, His is recombinant mouse tumor necrosis factor alpha (TNF-α) with his tag. Recombinant Mouse Tumor Necrosis Factor alpha, a major mediator of inflammation, is involved in a number of infectious and parasitic diseases.

HY-P7257

*Recombinant Human MIP-1 beta/CCL4* rHuMIP-1β/CCL4; C-C motif chemokine 4; LAG-1; Macrophage inflammatory protein 1-beta; SCYA4	Human	E. coli
Recombinant Human MIP-1 beta/CCL4 is a proinflammatory chemokine that both promotes leukocyte accumulation in various inflammatory conditions and contributes to protective immunity against human immunodeficiency virus type 1 (HIV-1) (1-5).

HY-P7364

*Recombinant Rat GRO alpha/CXCL1* (HEK293-expressed)** rRtGRO-α/CXCL1; Growth-regulated Alpha protein; C-X-C motif chemokine 1; CINC-1; SCYB1	Rat	HEK 293
Recombinant Rat GRO alpha/CXCL1 (HEK293 expressed) is a growth factor as well as a chemoattractant molecule, and is implicated as an oncogenic factor in several tumor types, including prostate and melanoma cancers.

HY-P7063

Recombinant Mouse Interleukin-6 rMuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2	Mouse	E. coli
Recombinant Mouse Interleukin-6 is a multifunctional cytokine that can regulate various immune and inflammatory responses.

HY-P7044

Recombinant Human Interleukin-6 rHuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2	Human	E. coli
Recombinant Human Interleukin-6 is a potent inducer of the synthesis of acute phase proteins in adult human hepatocytes.

HY-P7120

*Recombinant Human Transforming Growth Factor beta3 (HEK293-expressed)* rHuTGF-β3; TGFB3; LAP	Human	HEK 293
Recombinant Human Transforming Growth Factor β3 is a multifunctional cytokine which participated in cell differentiation, embryogenesis and development.

HY-P7299

*Recombinant Mouse Transforming Growth Factor beta2 (HEK293-expressed)* rMuTGF-β2; TGFB2; LAP	Mouse	HEK 293
Recombinant Mouse Transforming Growth Factor beta2 (HEK293-expressed) performs many cellular functions and has a vital role during embryonic development.

HY-P7376

Recombinant Rat Interleukin-3 beta rRtIL-3β; MCGF; Hematopoietic growth factor; P-cell stimulation factor	Rat	E. coli
Recombinant Rat Interleukin-3 beta induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cells. Recombinant Rat Interleukin-3 beta also functions in the nervous system and is important during the B-1 cell regulation of chronic inflammatory diseases.

HY-P7374

*Recombinant Human Interleukin-2 Receptor alpha/CD25, Fc Chimera (HEK293-expressed)* rHuIL-2R α/CD25, Fc Chimera; TAC antigen; IL-2-RA; IL-2 R Alpha; IL-2Rα; IL2RA	Human	HEK 293
Recombinant Human Interleukin-2 Receptor alpha/CD25, Fc Chimera (HEK293-expressed) is a subunit of interleukin-2 receptor, plays a critical role in regulating the IL-2-mediated responses by modulating the affinity of the IL-2R for the ligand.

HY-P7022

*Recombinant Human Interferon-alpha2a* rHuIFN-α2a; IFNA; IFNA2; IFN-a 2a	Human	E. coli
Recombinant Human Interferon-alpha2a is a cytokine belonging to the type I Interferons, acts as a regulatory mediator of the immune response, and also shows antiviral, antitumor activity.

HY-P7023

*Recombinant Human Interferon-alpha2b* rHuIFN-α2b; IFNA; INFA2; IFN-a 2b	Human	E. coli
Recombinant Human Interferon-alpha2b is a cytokine belonging to the type I Interferons, acts as a regulatory mediator of the immune response, and also shows antiviral, antitumor activity.

HY-P7044A

Recombinant Human Interleukin-6 (CHO-expressed) rHuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2	Human	CHO
Recombinant Human Interleukin-6 (CHO-expressed) is a potent inducer of the synthesis of acute phase proteins in adult human hepatocytes.

HY-P7016A

Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor rHuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-Alpha; Molgramostin; Sargramostim	Human	E. coli
Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor is a hematopoietic growth factor and immune modulator.

HY-P7215

*Recombinant Human Interleukin-2 Receptor alpha, His (HEK293-expressed)* rHuIL-2Rα, His; TAC-antigen; CD25	Human	HEK 293
Recombinant Human Interleukin-2 Receptor alpha, His (HEK293-expressed), also known at Tac antigen and a CD25, is a 42 kDa transmembrane protein. The interleukin 2 receptor alpha, beta and gamma chain constitute the high-affinity IL2 receptor.

HY-P7103A

Recombinant Rat Interleukin-6 (HEK293-expressed) rRtIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2	Rat	HEK 293
Recombinant Rat Interleukin-6 (HEK293-expressed) is a HEK293 cell derived multifunctional cytokine that can regulate various immune and inflammatory responses.

HY-P7205

*Recombinant Human Interleukin-1 beta* (CHO-expressed)** rHuIL-1β; Catabolin; IL1F2; IL1B	Human	CHO
Recombinant Human Interleukin-1 beta (CHO-expressed) could regulate the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.

HY-P7221

*Recombinant Human Interleukin-5 Receptor alpha* (CHO-expressed)** rHuIL-5Rα; IL-5R; IL-5RA; CD125	Human	CHO
Recombinant Human Interleukin-5 Receptor alpha (CHO-expressed) is a subunit of the Interleukin-5 receptor.

HY-P7377

*Recombinant Human Interleukin-6 Receptor alpha* (Sf9 insect cells-expressed)** rHuIL-6 Receptor α; gp80; CD126	Human	Sf9 insect cells
Recombinant Human Interleukin-6 Receptor alpha (Sf9 insect cells-expressed) is a type I transmembrane glycoprotein that forms a complex with type I transmembrane signal transducer protein gp130 (CD130) and mediates the biological activities of IL-6.

HY-P7119

Recombinant Human Transforming Growth Factor β2 TGF-beta-2; Cetermin; G-TSF; TGFB2; Polyergin; rHuTGF-β2	Human	HEK 293
Recombinant Human Transforming Growth Factor β2 is a multifunctional cytokine which participates in control of cell growth and differentiation, induces fibrosis, causes the suppression of immune response and has a vital role during embryonic development.

HY-P7069

Recombinant Mouse Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed) rMuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-Alpha; Molgramostin; Sargramostim	Mouse	CHO
Recombinant Mouse Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed) is a hematopoietic growth factor and immune modulator.

HY-P7094

Recombinant Rat Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed) rRtGM-CSF; CSF-2; MGI-1GM; Pluripoietin-Alpha; Molgramostin; Sargramostim	Rat	CHO
Recombinant Rat Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed) is a hematopoietic growth factor and immune modulator.

HY-P7016

Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed) rHuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-Alpha; Molgramostin; Sargramostim	Human	CHO
Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed) is a hematopoietic growth factor and immune modulator.

HY-P7016B

Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (P.pastoris-expressed) rHuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-Alpha; Molgramostin; Sargramostim	Human	P. pastoris
Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (P.pastoris-expressed) is a hematopoietic growth factor and immune modulator.

HY-P7193

Recombinant Human GRO gama/CXCL3 rHuGRO-γ/CXCL3; C-X-C motif chemokine 3; MIP2-beta	Human	E. coli
Recombinant Human GRO gama/CXCL3 mediates its effects on its target cell by interacting with a cell surface chemokine receptor.

HY-P7287

*Recombinant Human SDF-1 beta/CXCL12* rHuSDF-1β/CXCL12; C-X-C motif chemokine 12; PBSF	Human	E. coli
Recombinant Human SDF-1 beta/CXCL12 is a member of CXC chemokine family, binds to CXCR4 and CXCR7, and is implicated in tumor proliferation, survival, vascularization, metastasis, and immunosuppression.

HY-P7353

*Recombinant Human FGFR-1 alpha, Fc Chimera (Sf9 insect cells-expressed)* rHuFGFR-1α, Fc Chimera; BFGFR; CD331; FLT-2	Human	Sf9 insect cells
Recombinant Human FGFR-1 alpha, Fc Chimera (Sf9 insect cells-expressed) is a member of fibroblast growth factor receptors.

HY-P7191

*Recombinant Rat GRO beta/CXCL2* rRtGRO-β/CXCL2; MIP-2; CINC-3; C-X-C motif chemokine 2	Rat	E. coli
Recombinant Rat GRO beta/CXCL2 is a powerful neutrophil chemoattractant and is involved in many immune responses including wound healing, cancer metastasis, and angiogenesis.

HY-P7405

*Recombinant Human Signal regulatory protein alpha, His (HEK293-expressed)* rHuSignal regulatory protein α, His; CD172a; SHPS-1; BIT; MYD1	Human	HEK 293
Recombinant Human Signal regulatory protein alpha, His (HEK293-expressed) produced in HEK293 cells is a polypeptide chain amino acids with the C-termimal His tag. Signal regulatory protein alpha (SIRPα, designated CD172a) is a monomeric about 90kDa type I transmembrane glycoprotein that belongs to the SIRP/SHPS (CD172) family of the immunoglobulin superfamily.

HY-P7192

Recombinant Human GRO gama/CXCL3 (CHO-expressed) rHuGRO-γ/CXCL3; C-X-C motif chemokine 3; MIP2-beta	Human	CHO
Recombinant Human GRO gama/CXCL3 (CHO-expressed) mediates its effects on its target cell by interacting with a cell surface chemokine receptor.

HY-P7264

*Recombinant Mouse Macrophage Inflammatory Protein-3 beta/CCL19* rMuMIP-3β/CCL19; C-C motif chemokine 19; SCYA19	Mouse	E. coli
Recombinant Mouse Macrophage Inflammatory Protein-3 beta/CCL19 is a chemokine that binds to CCR7, modulates the inflammatory response.

HY-P7522

Recombinant Human APBA3, His
rHuAPBA3, His; Amyloid beta A4 precursor protein-binding family A member 3; APBA3
Human E. coli

HY-P7163

Recombinant Human Eotaxin-3/CCL26 rHuEotaxin-3/CCL26; C-C motif chemokine 26; MIP-4-Alpha; TSC-1; SCYA26	Human	E. coli
Recombinant Human Eotaxin-3/CCL26 signals exclusively via the CCR3 receptor and has eosinophil-selective chemoattractant activity.

HY-P7256

*Recombinant Human MIP-1 alpha/CCL3* rHuMIP-1α/CCL3; C-C motif chemokine 3; MIP1A; SCYA3	Human	E. coli
Recombinant Human MIP-1 alpha/CCL3 is a member of CC subfamily, exerting various biological effects by binding to its three cell surface receptors, including CCR1, CCR3, and CCR5.

HY-P7262

*Recombinant Human MIP-3 alpha/CCL20* rHuMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20	Human	E. coli
Recombinant Human MIP-3 alpha/CCL20 is a C-C motif chemokine ligand, and has CCR6 as its sole receptor.

HY-P7284

*Recombinant Human Stromal-Cell Derived Factor-1 alpha/CXCL12* rHuSDF-1α/CXCL12; C-X-C motif chemokine 12; PBSF	Human	E. coli
Recombinant Human Stromal-Cell Derived Factor-1 alpha/CXCL12 is a member of CXC chemokine family, binds to CXCR4 and CXCR7, and is implicated in tumor proliferation, survival, vascularization, metastasis, and immunosuppression.

HY-P7285

*Recombinant Mouse Stromal-Cell Derived Factor-1 alpha/CXCL12* rMuSDF-1α/CXCL12; C-X-C motif chemokine 12; PBSF	Mouse	E. coli
Recombinant Mouse Stromal-Cell Derived Factor-1 alpha/CXCL12 is a member of CXC chemokine family, binds to CXCR4 and CXCR7, and is implicated in tumor proliferation, survival, vascularization, metastasis, and immunosuppression.

HY-P7286

*Recombinant Rat Stromal-Cell Derived Factor-1 alpha/CXCL12* rRtSDF-1α/CXCL12; C-X-C motif chemokine 12; PBSF	Rat	E. coli
Recombinant Rat Stromal-Cell Derived Factor-1 alpha/CXCL12 is a member of CXC chemokine family, binds to CXCR4 and CXCR7, and is implicated in tumor proliferation, survival, vascularization, metastasis, and immunosuppression.

HY-P7406

*Recombinant Human Signal regulatory protein alpha, Fc Chimera (HEK293-expressed)* rHuSignal regulatory protein α, Fc Chimera; CD172a; SHPS-1; BIT; MYD1	Human	HEK 293
Recombinant Human Signal regulatory protein alpha (SIRPα), Fc Chimera (HEK293-expressed) produced in HEK293 cells is a polypeptide chain containing 572 amino acids with the C-termimal human IgG1 Fc fragment. Signal regulatory protein alpha (SIRPα, designated CD172a) is a monomeric about 90kDa type I transmembrane glycoprotein that belongs to the SIRP/SHPS (CD172) family of the immunoglobulin superfamily.

HY-P7254

*Recombinant Human MIP-1 alpha/CCL3 (CHO-expressed)* rHuMIP-1α/CCL3; C-C motif chemokine 3; MIP1A; SCYA3	Human	CHO
Recombinant Human MIP-1 alpha/CCL3 (CHO-expressed) is a member of CC subfamily, exerting various biological effects by binding to its three cell surface receptors, including CCR1, CCR3, and CCR5.

HY-P7260

*Recombinant Human MIP-3 alpha/CCL20 (CHO-expressed)* rHuMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20	Human	CHO
Recombinant Human MIP-3 alpha/CCL20 (CHO-expressed) is a C-C motif chemokine ligand, and has CCR6 as its sole receptor.

HY-P7263

*Recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20* rMuMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20	Mouse	E. coli
Recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20 is a C-C motif chemokine ligand, and has CCR6 as its sole receptor.

HY-P7161

Recombinant Human Eotaxin-2/CCL24 rHuEotaxin-2/CCL24; C-C motif chemokine 24; CK-beta-6; MPIF-2; MPIF2; SCYA24	Human	E. coli
Recombinant Human Eotaxin-2/CCL24 chemoattracts CCR3 bearing cells such as eosinophils, mast cells, basophils, and Th2 cells that play a role in allergic disorders.

HY-P7162

Recombinant Rat Eotaxin-2/CCL24 rRtEotaxin-2/CCL24; C-C motif chemokine 24; CK-beta-6; MPIF-2; MPIF2; SCYA24	Rat	E. coli
Recombinant Rat Eotaxin-2/CCL24 is chemotactic for resting T lymphocytes and eosinophils.

HY-P7229

Recombinant Human I-TAC/CXCL11 rHuI-TAC/CXCL11; C-X-C motif chemokine 11; beta-R1; H174; IP-9; SCYB11	Human	E. coli
Recombinant Human I-TAC/CXCL11 is a small cytokine belonging to the CXC chemokine family which can be strongly induced by IFN-gamma, and its receptor CXCR3.

HY-P7255

*Recombinant Mouse Macrophage Inflammatory Protein-1 alpha/CCL3 (HEK293-expressed)* rMuMIP-1α/CCL3; C-C motif chemokine 3; MIP1A; SCYA3	Mouse	HEK 293
Recombinant Mouse Macrophage Inflammatory Protein-1 alpha/CCL3 (HEK293-expressed) is a member of CC subfamily, exerting various biological effects by binding to its three cell surface receptors, including CCR1, CCR3, and CCR5.

HY-P7261

*Recombinant Rat Macrophage Inflammatory Protein-3 alpha/CCL20 (HEK293-expressed)* rRtMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20	Rat	HEK 293
Recombinant Rat Macrophage Inflammatory Protein-3 alpha/CCL20 (HEK293-expressed) is a C-C motif chemokine ligand, and has CCR6 as its sole receptor.

HY-P7403

*Recombinant Mouse Stromal-Cell Derived Factor-1 alpha/CXCL12 (CHO-expressed)* rMuSDF-1α/CXCL12; SDF-1; PBSF; C-X-C motif chemokine 12; TLSF	Mouse	CHO
Recombinant Mouse Stromal-Cell Derived Factor-1 alpha/CXCL12 (CHO-expressed) is a member of CXC chemokine family, binds to CXCR4 and CXCR7, and is implicated in tumor proliferation, survival, vascularization, metastasis, and immunosuppression.

HY-P7404

*Recombinant Mouse Stromal-Cell Derived Factor-1 beta/CXCL12 (CHO-expressed)* rMuSDF-1β/CXCL12; SDF-1; PBSF; C-X-C motif chemokine 12; TLSF	Mouse	CHO
Recombinant Mouse Stromal-Cell Derived Factor-1 beta/CXCL12 (CHO-expressed) is a member of CXC chemokine family, binds to CXCR4 and CXCR7, and is implicated in tumor proliferation, survival, vascularization, metastasis, and immunosuppression.

HY-P7228

Recombinant Human I-TAC/CXCL11 (HEK293-expressed) rHuI-TAC/CXCL11; C-X-C motif chemokine 11; beta-R1; H174; IP-9; SCYB11	Human	HEK 293
Recombinant Human I-TAC/CXCL11 (HEK293-expressed) is a small cytokine belonging to the CXC chemokine family which can be strongly induced by IFN-gamma, and its receptor CXCR3.

HY-P7231

Recombinant Human LD78 beta/CCL3L1 rHuLD78β/CCL3L1; C-C motif chemokine 3-like 1; SCYA3L1	Human	E. coli
Recombinant Human LD78 beta/CCL3L1 is a potent ligand for the HIV-1 co-receptor CCR5, which is essential for viral entry into human host cells.

HY-P7389

*Recombinant Human Macrophage Inflammatory Protein-1 beta/CCL4 (CHO-expressed)* rHuMIP-1β/CCL4; MIP-1β; C-C motif chemokine 4; ACT-2; SCYA4	Human	CHO
Recombinant Human Macrophage Inflammatory Protein-1 beta/CCL4 (CHO-expressed) is a proinflammatory chemokine that both promotes leukocyte accumulation in various inflammatory conditions and contributes to protective immunity against human immunodeficiency virus type 1 (HIV-1) (1-5).

HY-P7390

Recombinant Human MPIF/CCL23, 85a.a. (CHO-expressed) rHuMPIF/CCL23, 85a.a.; C-C motif chemokine 23; SCYA23; MPIF-1; Ck-beta8; MIP-3	Human	CHO
Recombinant Human MPIF/CCL23, 85a.a. (CHO-expressed) is a CC chemokine, induces endothelial cell migration and tube formation via CCR1.