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Results for "

Amiloride

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

1

Recombinant Proteins

1

Isotope-Labeled Compounds

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0285
    Amiloride
    Maximum Cited Publications
    25 Publications Verification

    MK-870

    		 Sodium Channel TRP Channel Apoptosis Cardiovascular Disease Metabolic Disease
    Amiloride (MK-870) is an inhibitor of both epithelial sodium channel (ENaC ) and urokinase-type plasminogen activator receptor (uTPA ). Amiloride is a blocker of polycystin-2 (PC2; TRPP2 ) channel.
    <em>Amiloride</em>
  • HY-B0285AR
    Amiloride hydrochloride (Standard)
    5+ Cited Publications

    MK-870 hydrochloride (Standard)

    		 Sodium Channel TRP Channel Apoptosis Cardiovascular Disease Metabolic Disease
    Amiloride (hydrochloride) (Standard) is the analytical standard of Amiloride (hydrochloride). This product is intended for research and analytical applications. Amiloride hydrochloride (MK-870 hydrochloride) is an inhibitor of both epithelial sodium channel (ENaC ) and urokinase-type plasminogen activator receptor (uTPA ). Amiloride hydrochloride is a blocker of polycystin-2 (PC2; TRPP2 ) channel.
    <em>Amiloride</em> hydrochloride (Standard)
  • HY-B0285A
    Amiloride hydrochloride
    Maximum Cited Publications
    25 Publications Verification

    MK-870 hydrochloride

    		 Sodium Channel TRP Channel Apoptosis Cardiovascular Disease Metabolic Disease
    Amiloride hydrochloride (MK-870 hydrochloride) is an inhibitor of both epithelial sodium channel (ENaC ) and urokinase-type plasminogen activator receptor (uTPA ). Amiloride hydrochloride is a blocker of polycystin-2 (PC2; TRPP2 ) channel.
    <em>Amiloride</em> hydrochloride
  • HY-B0285B
    Amiloride hydrochloride dihydrate
    Maximum Cited Publications
    25 Publications Verification

    MK-870 hydrochloride dihydrate

    		 Sodium Channel Apoptosis TRP Channel Cardiovascular Disease Metabolic Disease
    Amiloride hydrochloride dihydrate (MK-870 hydrochloride dihydrate) is an inhibitor of both epithelial sodium channel (ENaC ) and urokinase-type plasminogen activator receptor (uTPA ). Amiloride hydrochloride dihydrate is a blocker of polycystin-2 (PC2; TRPP2 ) channel.
    <em>Amiloride</em> hydrochloride dihydrate
  • HY-B0285AS
    Amiloride-15N3 hydrochloride

    MK-870-15N3 hydrochloride

    		 Apoptosis TRP Channel Sodium Channel
    Amiloride- 15N3 (hydrochloride) is the 15N labeled Amiloride hydrochloride[1]. Amiloride hydrochloride (MK-870 hydrochloride) is an inhibitor of both epithelial sodium channel (ENaC[2]) and urokinase-type plasminogen activator receptor (uTPA[3]). Amiloride hydrochloride is a blocker of polycystin-2 (PC2;TRPP2[4]) channel.
    <em>Amiloride</em>-15N3 hydrochloride
  • HY-128067
    5-(N,N-Hexamethylene)-amiloride
    1 Publications Verification

    Hexamethylene Amiloride; HMA

    		 Sodium Channel HIV Apoptosis Infection Cancer
    5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) derives from an amiloride and is a potent Na +/H + exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 μM and 1.34 μM, respectively .
    5-(N,N-Hexamethylene)-<em>amiloride</em>
  • HY-163365
    UTX-143

    		Na+/H+ Exchanger (NHE) Cancer
    UTX-143 is an inhibitor of Na+/H+ exchange protein (NHE5). UTX-143 has antitumor activity .
    UTX-143
  • HY-B1546A
    Benzamil hydrochloride

    BenzylAmiloride hydrochloride

    		 Na+/Ca2+ Exchanger Sodium Channel Neurological Disease
    Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na +/Ca 2+ exchanger (NCX) inhibitor (IC50~100 nM). Benzamil hydrochloride also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca 2+-activated currents, with an IC50 of 1.1 μM .
    Benzamil hydrochloride
  • HY-B1546
    Benzamil

    BenzylAmiloride
    Benzamil (Benzylamiloride), an Amiloride analogue, is a Na +/Ca 2+ exchanger (NCX) inhibitor (IC50~100 nM). Benzamil also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil inhibits TRPP3-mediated Ca 2+-activated currents, with an IC50 of 1.1 μM .
    Benzamil
  • HY-108464A
    Phenamil methanesulfonate

    		Sodium Channel TRP Channel Metabolic Disease Inflammation/Immunology
    Phenamil methanesulfonate, an analog of Amiloride (HY-B0285), is a more potent and less reversible epithelial sodium channel (ENaC) blocker with an IC50 of 400 nM . Phenamil methanesulfonate is also a competive inhibitor of TRPP3 and inhibits TRPP3-mediated Ca 2+ transport with an IC50 of 140 nM in a Ca 2+ uptake assay . Phenamil methanesulfonate is an intriguing small molecule to promote bone repair by strongly activating BMP signaling pathway . Phenamil methanesulfonate is used for the research of cystic fibrosis lung disease .
    Phenamil methanesulfonate

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