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Results for "

Amiodarone-d4

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14188S
    Amiodarone-d4 hydrochloride

    		Potassium Channel Autophagy Cardiovascular Disease Cancer
    Amiodarone-d4 (hydrochloride) is the deuterium labeled Amiodarone hydrochloride. Amiodarone hydrochloride, a benzofuran-based Class III antiarrhythmic agent, inhibits WT outwardIhERG tails with an IC50 of ∼45 nM[1]. Amiodarone hydrochloride induces cell proliferation and myofibroblast differentiation via ERK1/2 and p38 MAPK signaling in fibroblasts[2]. Amiodarone hydrochloride can be used in the research of both supraventricular and ventricular arrhythmias[1].
    <em>Amiodarone-d4</em> hydrochloride
  • HY-130353S
    Desethyl Amiodarone-d4 hydrochloride

    		Isotope-Labeled Compounds Potassium Channel Autophagy Cardiovascular Disease
    Desethyl Amiodarone-d4 (hydrochloride) is the deuterium labeled Desethylamiodarone hydrochloride. Desethylamiodarone hydrochloride (N-desethylamiodarone hydrochloride) is a major active metabolite of Amiodarone. Desethylamiodarone hydrochloride is formed by CYP3A isoenzymes. Amiodarone is an antiarrhythmic agent for inhibition of ATP-sensitive potassium channel with an IC50 of 19.1 μM[1][2][3].
    Desethyl <em>Amiodarone-d4</em> hydrochloride

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