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Results for "

Antibacteria

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (2) Bacterial (19) Beta-lactamase (2) DNA/RNA Synthesis (1) NF-κB (1) STAT (1) Thymidylate Synthase (8)
By Research Areas:	Cancer (2) Infection (19) Inflammation/Immunology (2)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0622

Morusin 4 Publications Verification Mulberrochromene	NF-κB STAT Bacterial	Infection Inflammation/Immunology Cancer
Morusin is a prenylated flavonoid isolated from Morus alba Linn. with various biological activities, such as antitumor, antioxidant, and anti-bacteria property. Morusin could inhibit NF-κB and STAT3 activity.

HY-N8089

Bis(dihydrochelerythrinyl)amine

Bacterial Infection Inflammation/Immunology

Bis(dihydrochelerythrinyl)amine possesses anti-bacteria activity .
HY-147274

Funobactam

XNW4107
Beta-lactamase Bacterial Infection

Funobactam (XNW4107) is a β-lactamase inhibitor, can be used for researching anti-bacteria .

Bis(dihydrochelerythrinyl)amine	Bacterial	Infection Inflammation/Immunology
Bis(dihydrochelerythrinyl)amine possesses anti-bacteria activity .

Funobactam XNW4107	Beta-lactamase Bacterial	Infection
Funobactam (XNW4107) is a β-lactamase inhibitor, can be used for researching anti-bacteria .

HY-146426

MraY-IN-2	Bacterial	Infection
MraY-IN-2 (compound 6) is a potent MurNAc-pentapeptide translocase (MraY) inhibitor with an IC₅₀ value of 4.5 μM. MraY-IN-2 can be used for researching anti-bacteria .

HY-146702

MtTMPK-IN-8	Bacterial Thymidylate Synthase	Infection
MtTMPK-IN-8 (compound 27) is a moderate M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor. MtTMPK-IN-8 has sub-micromolar activity against mycobacteria (MICs = 0.78~9.4 μM) without significant cytotoxicity. MtTMPK-IN-8 can be used for researching tuberculosis .

HY-146703

MtTMPK-IN-9	Bacterial Thymidylate Synthase	Infection
MtTMPK-IN-9 (compound 28) is a moderate M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC₅₀ value of 48 μM. MtTMPK-IN-9 has sub-micromolar activity against mycobacteria (MICs = 6.25~9.4 μM) without significant cytotoxicity. MtTMPK-IN-9 can be used for researching tuberculosis .

HY-146699

MtTMPK-IN-5	Bacterial Thymidylate Synthase	Infection
MtTMPK-IN-5 (compound 17) is a potent M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC₅₀ value of 34 μM. MtTMPK-IN-5 combines favorable enzyme inhibitory activity with significant activity against M. tuberculosis (MIC = 12.5 μM). MtTMPK-IN-5 can be used for researching tuberculosis .

HY-146700

MtTMPK-IN-6	Bacterial Thymidylate Synthase	Infection
MtTMPK-IN-6 (compound 1) is a potent M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC₅₀ value of 29 μM. MtTMPK-IN-6 can be used for researching tuberculosis .

HY-146701

MtTMPK-IN-7	Bacterial Thymidylate Synthase	Infection
MtTMPK-IN-7 (compound 26) is a moderate M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC₅₀ value of 47 μM. MtTMPK-IN-7 has sub-micromolar activity against mycobacteria (MICs = 2.3~4.7 μM) without significant cytotoxicity. MtTMPK-IN-7 can be used for researching tuberculosis .

HY-146075

β-Lactamase-IN-8	Beta-lactamase Bacterial	Infection
β-Lactamase-IN-8 (compound 20) is a potent and oral bioavailable broad-spectrum cyclic boronate β-lactamase inhibitor. β-Lactamase-IN-8 can be used for researching antibacteria .

HY-143482

MMV688844	Bacterial DNA/RNA Synthesis	Infection
MMV688844 is a potent Mycobacterium abscessus (Mabs) DNA Gyrase inhibitor with an IC₅₀ value of 2 μM. MMV688844 has bactericidal properties against Mabs bamboo with a MIC₅₀ of 12 μM. MMV688844 can be used for researching anti-bacteria .

HY-B1075A

Fosfomycin MK-0955	Bacterial Antibiotic	Infection
Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .

HY-144663

MtTMPK-IN-1	Bacterial Thymidylate Synthase	Infection
MtTMPK-IN-1 (compound 3) is a potent Mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC₅₀ value of 2.5 μM. MtTMPK-IN-1 has moderate to weak activity against Mtb H37Rv and low cytotoxicity in human fibroblast cells MRC-5. MtTMPK-IN-1 can be used for researching tuberculosis .

HY-144664

MtTMPK-IN-2	Bacterial Thymidylate Synthase	Infection
MtTMPK-IN-2 (compound 15) is a potent Mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC₅₀ value of 1.1 μM. MtTMPK-IN-2 has inhibitory activity against Mtb H37Rv (MIC = 12.5 μM). MtTMPK-IN-2 exhibits certain cytotoxicity in human fibroblast cells MRC-5 (EC₅₀ = 6.1 μM). MtTMPK-IN-2 can be used for researching tuberculosis .

HY-144665

MtTMPK-IN-3	Bacterial Thymidylate Synthase	Infection
MtTMPK-IN-3 (compound 25) is a potent Mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC₅₀ value of 0.12 μM. MtTMPK-IN-3 has inhibitory activity against Mtb H37Rv (MIC = 12.5 μM). MtTMPK-IN-3 exhibits certain cytotoxicity in human fibroblast cells MRC-5 (EC₅₀ = 12.5 μM). MtTMPK-IN-3 can be used for researching tuberculosis .

HY-146304

YXL-13	Bacterial	Infection
YXL-13 is a potent Pseudomonas aeruginosa (PAO1) inhibitor with an IC₅₀ value of 3.686 μM. YXL-13 can inhibit virulence factors and biofilm formation of PAO1. YXL-13 reduces the pathogenicity and agent resistance of PAO1 by inhibition of the quorum sensing (QS) system. YXL-13 can be used for researching anti-bacteria .

HY-144728

MraY-IN-3 hydrochloride	Bacterial	Infection
MraY-IN-1 (compound 12a) is a potent MraY inhibitor with an IC₅₀ value of 140 μM. MraY-IN-1 has antimicrobial activity against Escherichia coli K12, Bacillus subtilis W23 and Pseudomonas fluorescens Pf-5 with MIC₅₀s of 7 µg/mL, 12 µg/mL and 46 µg/mL, respectively. MraY-IN-1 can be used for researching anti-bacteria .

HY-B1075AS

(Rac)-Fosfomycin (benzylamine)-13C3 MK-0955 (benzylamine)-¹³C₃	Bacterial Antibiotic	Infection
(Rac)-Fosfomycin (benzylamine)- ¹³C₃ is the ¹³C labeled Fosfomycin[1]. Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[2][3].

HY-N10391

(-)-Cleistenolide Cleistenolide	Bacterial	Infection Cancer
(-)-Cleistenolide is a α,β-unsaturated δ-lactone isolated from Cleistochlamys kirkii Oliver. (-)-Cleistenolide has antibacterial and antitumor activity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0622

Morusin 4 Publications Verification Mulberrochromene	Structural Classification Classification of Application Fields Flavones Anti-aging Source classification Plants Infection Flavonoids other families Phenols Polyphenols Inflammation/Immunology Disease Research Fields	NF-κB STAT Bacterial
Morusin is a prenylated flavonoid isolated from Morus alba Linn. with various biological activities, such as antitumor, antioxidant, and anti-bacteria property. Morusin could inhibit NF-κB and STAT3 activity.

HY-N8089

Bis(dihydrochelerythrinyl)amine	Alkaloids Classification of Application Fields Chelidonium majus Source classification Plants Disease Research Fields Inflammation/Immunology Papaveraceae Alkaloid Dimers	Bacterial
Bis(dihydrochelerythrinyl)amine possesses anti-bacteria activity .

HY-N10391

(-)-Cleistenolide Cleistenolide	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Annonaceae Disease Research Fields Cleistochlamys kirkii Oliver Cancer	Bacterial
(-)-Cleistenolide is a α,β-unsaturated δ-lactone isolated from Cleistochlamys kirkii Oliver. (-)-Cleistenolide has antibacterial and antitumor activity .

Cat. No.	Product Name	Chemical Structure

HY-B1075AS

(Rac)-Fosfomycin (benzylamine)-13C3
(Rac)-Fosfomycin (benzylamine)- ¹³C₃ is the ¹³C labeled Fosfomycin[1]. Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[2][3].

(Rac)-Fosfomycin (benzylamine)-13C3

(Rac)-Fosfomycin (benzylamine)- ¹³C₃ is the ¹³C labeled Fosfomycin[1]. Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[2][3].

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