Search Result
Results for "
Antibiotic
" in MedChemExpress (MCE) Product Catalog:
2141
Inhibitors & Agonists
11
Biochemical Assay Reagents
168
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-B1915
-
|
Gentamicin C2b; Antibiotic XK-62-2; Sagamicin
|
Antibiotic
Bacterial
|
Infection
|
|
Micronomicin (Gentamicin C2b) is an aminoglycoside antibiotic, with antibacterial and bactericidal activities .
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-
-
- HY-100833
-
-
-
- HY-137085
-
|
|
Antibiotic
Fungal
|
Infection
|
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Antibiotic AB023b is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023a (HY-137084). Antibiotic AB023b exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea, Fusarium moniliforme and Pythium ultimum .
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-
-
- HY-137084
-
|
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Antibiotic
Fungal
|
Infection
|
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Antibiotic AB023a is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023b (HY-137085). Antibiotic AB023a exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea (MIC= 5 μg/mL), Fusarium moniliforme and Pythium ultimum .
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-
-
- HY-121405
-
|
Antibiotic K16
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Antibiotic
Parasite
|
Infection
|
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Malonomicin (Antibiotic K16) is an antibiotic with anti-protozoa and anti-trypanosome activities. Malonomicin also shows anti-trypanosome activity in vivo .
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-
-
- HY-120333
-
|
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Antibiotic
Fungal
Bacterial
|
Infection
|
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Antibiotic PF 1052 is an antibiotic extracted from a natural product library. Antibiotic PF 1052 has an inhibitory effect on murine neutrophil migration .
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-
-
- HY-113602
-
|
Antibiotic 273 A1-beta
|
Antibiotic
Bacterial
|
Infection
|
|
Paldimycin B (Antibiotic 273 A1-beta) is a powerful semi-synthetic antibiotic with antibacterial activity against S. aureus and coagulase-negative staphylococci .
|
-
-
- HY-P2364
-
|
Antibiotic 1907-II
|
Antibiotic
Parasite
|
Infection
|
|
Leucinostatin B (Antibiotic 1907-II) is a peptide antibiotic with antitrypanosomal activities, which is found in soil fungi, Paecilomyces sp.. Leucinostatin B shows activity against both strains GUTat 3.1 and STIB900 with IC50 values ranging from 3.4-8.3 ng/mL .
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-
-
- HY-165272
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Antibiotic SF-2132 is a peptide antibiotic identified in Nocardiopsis sp., which exhibits inhibitory activity against β-lactam antibiotic-resistant strains, such as Pseudomonas and Escherichia .
|
-
-
- HY-113622
-
|
Palmarumycin C13; Diepoxin ζ; Antibiotic Sch53514
|
Fungal
Antibiotic
|
Infection
|
|
Cladospirone bisepoxide is a metabolite that isolated from cultures of a fungus. Cladospirone bisepoxide displays selective antibiotic activity against several bacteria and fungi and inhibits germinations of Lepidium sativum at low concentrations .
|
-
-
- HY-136822
-
-
-
- HY-135171
-
|
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Antibiotic
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Others
|
|
Antibiotic JI 20A is an aminocyclol antibiotic derived from Micronionospora. The structure of Antibiotic JI 20A is related to gentamicin .
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-
-
- HY-14366
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Antibiotic A-338533, an antibiotic, can be isolated from Streptomyces strain. Antibiotic A-338533 has anti-bacterial activity against Staphylococcus aureus, Mycoplasma gallisepticum with MIC values of 2 μg/mL and ≤1.56 μg/mL, respectively .
|
-
-
- HY-B1222A
-
|
Antibiotic 6640; Rickamicin
|
Bacterial
Antibiotic
|
Infection
|
|
Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria .
|
-
-
- HY-128488
-
-
-
- HY-N12913
-
|
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Antibiotic
Fungal
|
Infection
|
|
Antibiotic WB is an antibioticwith antifungal activity and can be isolated from the soil fungus strain 38 .
|
-
-
- HY-A0097A
-
|
Antibiotic MDL-507 sodium; MDL-507 sodium
|
Antibiotic
HIV
SARS-CoV
|
Infection
|
|
Teicoplanin sodium is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin sodium shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity .
|
-
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- HY-12820
-
|
Antibiotic-202
|
Bacterial
Antibiotic
|
Infection
|
|
Sibofimloc (Antibiotic-202) is a first-in-class, gut-restricted, orally active FimH adhesion inhibitor extracted from patent WO2014100158A1, Compound Example 202. Sibofimloc has anti-bacterial infective activity. Sibofimloc is developed for inflammatory bowel disease (IBD) .
|
-
-
- HY-126826
-
-
-
- HY-136666
-
|
|
Bacterial
|
Others
|
|
Antibiotic AC4437 is a compound with antimicrobial activity isolated from specific soil microorganisms and has an inhibitory effect on Bacillus subtilis.
|
-
-
- HY-N1724
-
|
Antibiotic X 4357B; Folimycin; X 4357B
|
Proton Pump
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
Cancer
|
|
Concanamycin A (Folimycin; Antibiotic X 4357B) is a macrolide antibiotic, a vacuolar type H +-ATPase (V-ATPase) inhibitor. Concanamycin A is also an inhibitor of lysosomal acidification, can be used to T cell-mediated inflammation research - .
|
-
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- HY-112661
-
|
Antibiotic PC-766B
|
Antibiotic
Bacterial
Fungal
|
Infection
Cancer
|
|
PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na +, K +-ATPase .
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-
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- HY-P2047
-
|
Antibiotic FR-900201
|
Antibiotic
Bacterial
|
Infection
|
|
Lavendomycin is a peptide antibiotic from Streptomyces. Lavendomycin inhibits Gram-positive bacteria .
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-
-
- HY-161870
-
|
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Antibiotic
|
Infection
|
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Antibiotic adjuvant 1 (compound 3e) is an antibiotic adjuvant that presents insufficient antibacterial activity (MIC > 128 µg/mL) and potentiate the activity of Cloxacillin (HY-B0466A)(66-fold) with synergistic effect .
|
-
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- HY-19965
-
|
Antibiotic UK 2A
|
Antibiotic
Fungal
|
Infection
|
|
UK-2A (Antibiotic UK 2A) is a potent antifungal antibiotic. UK-2A shows antifungal activity .
|
-
-
- HY-P2450
-
|
Antibiotic P168
|
Fungal
Antibiotic
|
Infection
Cancer
|
|
Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies .
|
-
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- HY-B1908
-
|
SF-837; Antibiotic SF-837
|
Bacterial
Antibiotic
|
Infection
|
|
Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria.
|
-
-
- HY-107767
-
|
DC 81
|
Antibiotic
Apoptosis
DNA/RNA Synthesis
|
Cancer
|
|
Antibiotic DC 81 (DC 81), an antitumor antibiotic produced by Streptomyces species, is a PBD (pyrrolo[2,1-c][1,4]benzodiazepine). Antibiotic DC 81 is potent inhibitor of nucleic acid synthesis. Antibiotic DC 81 can recognize and bind to specific sequences of DNA and form a labile covalent adduct .
|
-
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- HY-108191
-
|
Antibiotic 273a1α
|
Bacterial
Antibiotic
|
Infection
|
|
Paldimycin A (Antibiotic 273a1α) is an antibiotic derived from Streptomyces paulus, primarily targeting Gram-positive bacteria. Paldimycin A exerts its antibacterial effects by interfering with bacterial protein synthesis and cell membrane function .
|
-
-
- HY-126788
-
|
DC 102
|
Antibiotic
|
Infection
Metabolic Disease
|
|
Antibiotic DC 102 is a new glycosidic pyrrole(1,4)benzodiazepine antibiotic with a MIC value of 42 μg/mL target Bacillus subtilis No. 10707. Antibiotic DC 102 has an LD50 value of 1.5mg/mL(i.p) in mouse .
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-
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- HY-103397A
-
|
Antibiotic YS-02931K-β
|
Biochemical Assay Reagents
|
Infection
|
|
Dihydrokalafungin (Antibiotic YS-02931K-β) is a benzoisochromanequinone that used as a natural substrate in enzyme assays of the ActVB-ActVA system .
|
-
-
- HY-15739
-
-
-
- HY-19606
-
|
Antibiotic MI 43-37F11
|
Interleukin Related
NO Synthase
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Cytogenin (Antibiotic MI 43-37F11) is an orally active antineoplastic antibiotic. Cytogenin regulates the inflammatory cytokine, reduces the levels of iNOS, NO and IL-6 in mouse macrophages, and exhibits antidiabetic efficacy in mice. Cytogenin inhibits growth of Ehrlich ascites tumor in mouse model .
|
-
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- HY-108718
-
|
Geneticin; Antibiotic G-418
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
G-418 (Geneticin) is an aminoglycoside antibiotic with a structure similar to gentamicin. It is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis .
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-
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- HY-123720
-
|
Antibiotic EV22; L-660631
|
Antibiotic
Fungal
|
Infection
|
|
Sch 31828 is a novel antifungal antibiotic, with mean MICs against Candida of 0.034 /g/mL .
|
-
-
- HY-122507
-
|
A 28695A; Antibiotic A 28695A
|
Antibiotic
|
Infection
|
|
Septamycin (A 28695A) is a metal complexing polyether antibiotic. Septamycin is produced by a strain of Streptomyces hygroscopicus NRRL 5678. Septamycin has anticoccidial activity .
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-
-
- HY-A0097
-
|
Antibiotic MDL-507; MDL-507
|
Bacterial
Antibiotic
|
Infection
|
|
Teicoplanin is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity .
|
-
-
- HY-108307
-
|
Gentamicin C2b sulfate; Antibiotic XK-62-2 sulfate; Sagamicin sulfate
|
Antibiotic
Bacterial
|
Infection
|
|
Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside antibiotic isolated from Micromonospora. Micronomicin sulfate is a broad-spectrum antibiotic close to the gentamicin-type antibiotics, exhibits a high activity against Pseudomonas, Proteus, Klebsiella pneumoniae, Serratia, etc (MIC=0.001-8.3 μg/ml) .
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-
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- HY-117818
-
|
Antibiotic DC 116
|
Antibiotic
|
Cancer
|
|
Sapurimycin is an antitumor antibiotic isolated from Streptomyces DO-116 and belongs to the capramycin family. Sapurimycin exhibits potent activity against Gram-positive bacteria and exhibits significant antitumor effects against leukemia P388 and sarcoma 180 in mouse models. In vitro studies have shown that Sapurimycin can induce single-strand breaks in supercoiled plasmid DNA .
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-
-
- HY-17561
-
|
Geneticin sulfate; Antibiotic G-418 sulfate
|
Bacterial
Antibiotic
|
Infection
|
|
G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells .
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- HY-N6687
-
|
A-23187; Antibiotic A-23187
|
Oxidative Phosphorylation
Bacterial
Fungal
Apoptosis
Autophagy
Antibiotic
|
Infection
Cancer
|
|
Calcimycin (A-23187) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin induces Ca 2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin induces apoptosis .
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-
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- HY-118593
-
|
Madumycin II; Antibiotic A 2315A
|
Antibiotic
|
Infection
|
|
A2315A (Madumycin II) is an alanine-containing streptogramin A antibiotic. A2315A is a potent peptidyl transferase center (PTC) inhibitor. A2315A inhibits the ribosome prior to the first cycle of peptide bond formation .
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-
-
- HY-B1071
-
-
-
- HY-129454
-
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Antibiotic TPU-0037-A
|
Antibiotic
|
Infection
|
|
TPU-0037A is an antibiotic and a congener of lydicamycin. It inhibits the growth of Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA), B. subtilis, and M. luteus (MICs=1.56-12.5 μg/mL), but not Gram-negative E. coli, P. mirabilis, P. vulgaris, or P. aeruginosa strains (MICs=>50 μg/mL).
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-
-
- HY-P10795
-
|
Antibiotic NK 2
|
Parasite
Bacterial
Fungal
|
Infection
|
|
NK-2 (Antibiotic NK 2), a shortened linear amphipathic NK-Lysin analog (comprising residues 39 to 65 of NK-lysin), is an antimicrobial peptide that exhibits potent activities against trypanosoma cruzi, Candida albicans, gram-positive and gram-negative bacteria. NK-2 can kill trypanosomes residing inside the human glioblastoma cell line 86HG39, left the host cells apparently unharmed .
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-
-
- HY-115669
-
|
Antibiotic A 15104 Y; PClP
|
Myosin
TGF-β Receptor
|
Cancer
|
|
Pentachloropseudilin (Antibiotic A 15104 Y; PClP) is a reversible and allosteric potent inhibitor of Myo1s (class 1 myosins) with IC50s range from 1 to 5 μM for mammalian class-1 myosins and greater than 90 μM for class-2 and class-5 myosins. Pentachloropseudilin is a potent inhibitor of transforming growth factor-β (TGF-β)-stimulated signaling, with an IC50 of 0.1 to 0.2 μM for TGF-β .
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-
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- HY-121716
-
|
Antibiotic 2088A; LL-14I352α
|
Bacterial
|
Cancer
|
|
Pelagiomicin A is a novel phenazine antibiotic produced by the marine bacterium Pelagiobacter variabilis. The compound is unstable in water and small alcohols. The absolute structure of its major component, Pelagiomicin A, as well as the properties of minor amounts of other structures, were determined by spectroscopic data and synthesis. Pelagiomicin A is active against both Gram-positive and Gram-negative bacteria and exhibits antitumor activity in vitro and in vivo.
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-
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- HY-N6687B
-
|
A-23187 hemimagnesium; Antibiotic A-23187 hemimagnesium
|
Oxidative Phosphorylation
Bacterial
Fungal
Apoptosis
Autophagy
|
Infection
Cancer
|
|
Calcimycin (A-23187) hemimagnesium is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemimagnesium induces Ca 2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemimagnesium inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemimagnesium also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemimagnesium induces apoptosis .
|
-
-
- HY-N6687A
-
|
A-23187 hemicalcium salt; Antibiotic A-23187 hemicalcium salt
|
Oxidative Phosphorylation
Bacterial
Fungal
Apoptosis
Autophagy
Antibiotic
|
Infection
Cancer
|
|
Calcimycin hemicalcium salt (A-23187 hemicalcium salt) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemicalcium salt induces Ca 2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemicalcium salt inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemicalcium salt also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemicalcium salt induces apoptosis .
|
-
-
- HY-130340
-
|
Teichomycin A3 factor 1; Antibiotic L 17054
|
Antibiotic
|
Infection
|
|
Teicoplanin A3-1 is a degradation product of teicoplanins A2-1 to 5 (Item Nos. 20187, 20188, 20189, 20192). Teicoplanins are glycopeptide antibiotics produced by A. teichomyceticus that are broadly effective against Gram-positive bacteria in vitro.
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-
- HY-100833R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cabozantinib (S-malate) (Standard) is the analytical standard of Cabozantinib (S-malate). This product is intended for research and analytical applications. Cabozantinib S-malate (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.
|
-
- HY-N6732
-
|
SF2370; Antibiotic K 252a; Antibiotic SF 2370
|
PKC
PKA
CaMK
Trk Receptor
Autophagy
Antibiotic
|
Infection
Inflammation/Immunology
|
|
K-252a, a staurosporine analog, inhibits protein kinase, with IC50 values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca 2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively . K-252a is a potent inhibitor (IC50 of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene .
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-
- HY-126699
-
|
Antibiotic TAN 420D
|
Bacterial
|
Infection
|
|
Herbimycin C is a bacterial metabolite originally isolated from S. hygroscopicus. It is cytotoxic to HeLa and Ehrlich cells (IC50s=7.3 and 1.2 μg/mL, respectively).
|
-
- HY-117986
-
|
Antibiotic AB3217A
|
Parasite
|
Infection
|
|
AB 3217-A, an anti-mite substance, can be isolated from the fermentation broth of a streptomycete strain .
|
-
- HY-P2331
-
|
Antibiotic A 3802-IV-3; Gardimycin
|
Antibiotic
|
Infection
|
|
Actagardin is a tetracyclic lantibiotic produced by several species of Actinoplanes. It is composed of macrocyclic rings formed by thioether bridges. Actagardin preferably targets Gram-positive bacteria, inhibiting the synthesis of peptidoglycan.
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-
- HY-15141
-
|
Antibiotic AM-2282; STS; AM-2282
|
PKC
PKA
Apoptosis
Bacterial
Fungal
Antibiotic
|
Infection
Cancer
|
|
Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC50 of 3 μM. Staurosporine is an apoptosis inducer .
|
-
- HY-129694
-
|
Ro 21-6150; Antibiotic A-130-A
|
β-catenin
CDK
Reactive Oxygen Species
|
Cancer
|
|
Lenoremycin (Ro 21-6150) is a microbial metabolite. Lenoremycin decreases β-catenin and cyclin D1 proteins levels. Lenoremycin decreases cancer stem cells (CSCs) populations via inducing reactive oxygen species production .
|
-
- HY-101938
-
-
- HY-104051
-
-
- HY-105393
-
|
Antibiotic LB 10517 sodium
|
Bacterial
|
Infection
|
LB 10517 (sodium) is a type of cephalosporin. LB 10517 (sodium) has broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria, including Enterobacteriaceae, Pseudomonas aeruginosa, Staphylococcus, and Streptococcus .
|
-
- HY-15141G
-
|
Antibiotic AM-2282; STS; AM-2282
|
PKC
|
Infection
Cancer
|
|
Staurosporine (AM-2282) (GMP) is Staurosporine (HY-15141) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases .
|
-
- HY-134090
-
|
Antibiotic TS 885; NSC 248958
|
Bacterial
|
Infection
|
|
9-Methylstreptimidone is a microbial metabolite originally isolated from Streptomyces sp. S-885 that has antifungal and antiviral activities. It is active against several fungi, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus (MICs=4-20 μg/mL) and has antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro (MIC=0.02 μg/mL for all). 9-Methylstreptimidone increases survival in mouse models of infection with influenza A2 (H2N2) or C. albicans when administered prior to infection.
|
-
- HY-111221
-
-
- HY-B1071A
-
-
- HY-16384
-
|
Antibiotic L 156602; PD 124966
|
Complement System
|
Inflammation/Immunology
|
|
L-156602 is a C5a receptor antagonist. L-156602 inhibits inflammation, and the migration of monocytes and neutrophils to the infiltrating site in mouse inflammatory models. L-156602 suppresses the efferent phase of delayed-type hypersensitivity (DTH) .
|
-
- HY-171233
-
|
|
Bacterial
|
Infection
|
|
MRSA antibiotic 2 (compound 2) shows MIC of 2 μg/mL for S. aureus (MRSA). MRSA antibiotic 2 selectively target Gram-positive bacteria over Gram-negative bacteria and human cells .
|
-
- HY-135181
-
-
- HY-120009
-
-
- HY-126479
-
-
- HY-129312
-
-
- HY-111134
-
|
|
Antibiotic
|
Infection
Cancer
|
|
TAN 420C is an antibiotic that shows a strong cytotoxic activity against the lymphocytic leukemia .
|
-
- HY-126696
-
-
- HY-P1612
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Hormaomycin is a potent and selective macrocyc antibiotic agent. Hormaomycin has broad-spectrum antibiotic activity against numerous Gram-positive .
|
-
- HY-122285
-
-
- HY-163321
-
|
|
Antibiotic
|
Infection
|
|
DapE-IN-1 (compound 3y) is a diaminopimelate desuccinylase (DapE) inhibitor and a potentially potent antibiotic .
|
-
- HY-117566
-
-
- HY-124262
-
-
- HY-125539
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Roridin E is an antibiotic that has cell-inhibiting and fungicidal activities similar to verrucarin .
|
-
- HY-B1864C
-
|
Ksg sulfate
|
Antibiotic
Fungal
|
Infection
|
Kasugamycin (sulfate) is an aminoglycoside antibiotic that can be used to treat rice blast caused by fungi .
|
-
- HY-113582
-
-
- HY-122327
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Nodusmicin is a macrolide antibiotic against antibiotic-susceptible and -resistant S. aureus with MIC values of 125, 250 and 250 μg/mL for UC-76, UC-6685, and UC-6690 strains, respectively .
|
-
- HY-P5728
-
-
- HY-120579
-
-
- HY-113562
-
-
- HY-130069
-
-
- HY-N9425
-
-
- HY-157987
-
|
|
Bacterial
|
Infection
|
|
MBX3135 is an efflux pump inhibitor which can enhance the effect of antibiotics through the AcrB target of bacteria. MBX3135 can be used for research of infection and antibiotics .
|
-
- HY-122415
-
|
|
Antibiotic
|
Infection
|
|
Tunicamine is a high carbohydrate antibiotic that is part of the structure of Tunicamycin. Tunicamycin is a nucleoside antibiotic and a reversible polyprenol-phosphate inhibitor .
|
-
- HY-B1682
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Loracarbef, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class .
|
-
- HY-B1682A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Loracarbef hydrate, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class .
|
-
- HY-P5726
-
|
|
Antibiotic
|
Cancer
|
|
Aurein 1.2 is an active amphibian antibiotic peptide with antibiotic and anticancer activities .
|
-
- HY-126605
-
|
|
Bacterial
|
Infection
|
|
Trinactin is a macrotetrolide antibiotic. Trinactin also is a cation carrier .
|
-
- HY-129342
-
|
|
Antibiotic
|
Infection
|
|
Lincomycin B is an antibiotic that can be isolated from Streptomyces lincolnensis .
|
-
- HY-121395
-
|
|
Antibiotic
Fungal
|
Infection
|
Lepiochlorin is an antibiotic metabolite produced by a fungus (Lepiota species) that is cultivated by ants, which can prevent fungal contamination .
|
-
- HY-P5725
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Aurein 2.1 is an antibiotic peptide that can be found in the Australian Bell Frogs Litoria aurea and Litoria raniformis .
|
-
- HY-125720
-
|
|
Antibiotic
|
Infection
|
|
A-39183A is an antibiotic that shows significant cytotoxicity to HeLa cells, with an IC50 value of 1.8 μM .
|
-
- HY-113945
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Abbeymycin is an antibiotic derived from the actinobacterium Streptomyces sp. AB-999F-52. Abbeymycin is a specifically acting antibiotic with antimicrobial activity, primarily targeting anaerobic bacteria. Abbeymycin is employed in research concerning antibiotic discovery and screening .
|
-
- HY-B0507S
-
-
- HY-W439855
-
-
- HY-118992
-
|
X 5108; Goldinomycin
|
Antibiotic
Bacterial
|
Infection
|
|
Aurodox (X 5108) is an antibiotic obtained from a streptomyces variant, Aurodox can against a number of gram-positive bacteria. Aurodox shows a very low toxicity in mice and promoted poultry growth .
|
-
- HY-N13149
-
-
- HY-105113
-
-
- HY-N13147
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Tetromycin C5 is an antibiotic, that exhibits board-spectrum antibacterial activity against gram-positive bacteria and their drug-resistant bacteria .
|
-
- HY-B0273S1
-
-
- HY-24463
-
|
|
Antibiotic
|
Others
|
|
3,4-Di-O-acetyl-L-fucal is the reactant for synthesis antibiotics (extracted from patent WO1999026956A1) .
|
-
- HY-B0507
-
-
- HY-17028A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
(Rac)-Besifloxacin hydrochloride is the enantiomer of Besifloxacin hydrochloride. Besifloxacin hydrochloride is a broad-spectrum fourth-generation fluoroquinolone antibiotic .
|
-
- HY-125358
-
|
MK 2266 B
|
Antibiotic
Fungal
|
Infection
|
|
Dactylfungin B (MK 2266 B) is an antifungal antibiotic that is active against Candida pseudotropicalis and other fungi, with an MIC value at <10 μg/mL .
|
-
- HY-126867
-
-
- HY-135532
-
|
|
Antibiotic
|
Infection
|
|
Amoxicillin-clavulanate potassium is an antibiotic. Amoxicillin-clavulanate potassium has the potential for the research of various bacterial infection .
|
-
- HY-119405
-
-
- HY-115843
-
-
- HY-126602
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Kinamycin B is an antibiotic found in Streptomyces murayamaensis of the genus Streptomyces that exhibits antifungal activity .
|
-
- HY-N8252
-
|
|
Antibiotic
|
Infection
|
|
Xanthoquinodin A1 is an anticoccidial antibiotic having a new xanthone-anthraquinone conjugate system .
|
-
- HY-125732
-
|
|
Antibiotic
|
Infection
|
|
Decarestrictine D exhibits inhibitory activity against cholesterol levels. Decarestrictine D is utilized as receptor for glycosylation reactions to synthesize novel hybrid antibiotics .
|
-
- HY-N3300
-
-
- HY-123350
-
|
|
Antibiotic
|
Infection
|
|
Saroaspidin B, a dimer of a phloroglucinol moiety, is an antibiotic compound .
|
-
- HY-126577
-
|
|
Antibiotic
Bacterial
|
|
|
Dactylocycline B, an antibiotic, is active against gram-positive bacteria, including tetracycline-resistant bacteria .
|
-
- HY-113629R
-
|
|
Drug Metabolite
|
Infection
|
|
Cefixime (trihydrate) (Standard) is the analytical standard of Cefixime (trihydrate). This product is intended for research and analytical applications. Cefixime trihydrate (FR-17027 trihydrate) is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections .
|
-
- HY-161018
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
CF3–K11 is a stable antibiotic with antibacterial activity. CF3–K11 has strong antibacterial activity against Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus (MRSA).
|
-
- HY-123552
-
|
|
Antibiotic
|
Infection
|
|
RK-1441A is a pyrrolobenzodiazepine antibiotic with antibacteriophage activity .
|
-
- HY-126559
-
|
Mycotrienin I
|
Fungal
Antibiotic
|
Infection
|
|
Ansatrienin A is an antifungal antibiotic that can be isolated from Streptomyces collinus .
|
-
- HY-126838
-
|
|
Antibiotic
|
Infection
|
|
Lavendofuseomycin is a macrolide pentaene antibiotic that can be utilized for antibacterial research .
|
-
- HY-121050
-
|
W7783
|
Antibiotic
Fungal
|
Infection
|
|
Ambruticin (W7783) is an orally active and potent antifungal antibiotic. Ambruticin represents a class of antibiotics, that can be isolated from a strain of Polyangium cellulosum var. fulvum, a bacterium belonging to the class Myxobacteriales. Ambruticin is a cyclopropyl-polyene-pyran acid and is active against fungi .
|
-
- HY-P3884
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Arylomycin A2, an antibiotic (Antibiotic), is a lipopeptide type I signal peptidase (SPase I) inhibitor. Arylomycin A2 has antibacterial effects .
|
-
- HY-138083
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Parvodicin C2 is a glycopeptide antibiotic that can be isolated from parvosata. Parvodicin C2 has antibacterial activity .
|
-
- HY-136428
-
|
|
Drug Metabolite
|
Cancer
|
|
Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound .
|
-
- HY-121347
-
-
- HY-B0220S3
-
|
|
Bacterial
|
Infection
|
|
Erythromycin- 13C2 is a macrolide antibiotic that can be used to treat respiratory infections, skin infections, and chlamydia infections .
|
-
- HY-A0153
-
-
- HY-A0153A
-
|
Cefapirin sodium
|
Bacterial
Antibiotic
|
Infection
|
|
Cephapirin sodium (Cefapirin sodium) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .
|
-
- HY-116272
-
-
- HY-111331
-
|
|
Antibiotic
Hexokinase
|
Infection
|
|
Germicidin B is an antibiotic with bactericidal properties. Germicidin B can inhibit hexokinase II, with an IC50 of 25.16 μM .
|
-
- HY-150523
-
|
|
Antibiotic
|
Infection
|
|
Ristocetin is a glycopeptide antibiotic. Ristocetin induces platelet aggregation. Ristocetin can be used for Research of Von Willebrand’s disease .
|
-
- HY-B0276
-
|
2-Ethylthioisonicotinamide
|
Bacterial
Antibiotic
|
Infection
|
|
Ethionamide (2-ethylthioisonicotinamide) is a second-line anti-tuberculosis antibiotic with antibacterial effect and oral activity .
|
-
- HY-126746
-
|
|
Antibiotic
|
Infection
|
|
Corynecin I is an antibiotic produced by Corynebacterium hydrocarboclastus, and its precursor (D-(-) threo-p-amino phenyl serinol-N-acetylamine) has a minimal inhibitory effect on the synthesis of Corynecin from mevalonic acid .
|
-
- HY-112663
-
|
|
Antibiotic
|
Infection
|
|
Monazomycin is a polyene-like antibiotic produced by Streptomyces. Monazomycin molecular weight is about 1200 .
|
-
- HY-17565A
-
|
|
DNA/RNA Synthesis
Antibiotic
|
Cancer
|
|
Bleomycin hydrochloride is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic .
|
-
- HY-16035
-
|
|
DNA/RNA Synthesis
Antibiotic
|
Cancer
|
|
Alatrofloxacin, the parenteral proagent of Trovafloxacin, is a fluoronaphthyridone which contains an L-alanyl-L-alanyl salt. Alatrofloxacin functions similar to other fluoroquinolone antibiotics in that it not only has antibiotic activity to kill invading organisms by interfering with DNA synthesis, it possesses immunosuppressive activity .
|
-
- HY-119604
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cafamycin is a polyether antibiotic active against gram-positive bacteria, including Staphylococcus aureus. Cafamycin also demonstrates insecticidal and antiprotozoal activities. Cafamycin is isolated from the culture fluid of Streptomyces sp., an organism producing the anthracycline antibiotic galtamycin .
|
-
- HY-125395
-
-
- HY-P2599
-
-
- HY-126406
-
-
- HY-15087A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Spergualin trihydrochloride is a natural occurring antibiotic initially identified from culture filtrates of Bacillus laterosporus BMG162-aF2 .
|
-
- HY-130339
-
-
- HY-P10211
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Virgilagicin is a Gram-positive active antibiotic that has a dual polyprenyl phosphate binding mechanism that impedes resistance development .
|
-
- HY-130338
-
-
- HY-157492
-
|
|
Bacterial
|
Infection
|
|
RO7075573 (compound 3) is an antibiotics that targets the lipopolysaccharide (LPS) transport machine in Acinetobacter. RO7075573 protects mice from A. baumannii infections .
|
-
- HY-105981
-
|
GR 50692; TA 5901
|
Antibiotic
Bacterial
|
Infection
|
|
Cefempidone (GR 50692) is a third-generation cephalosporin antibiotic. Cefempidone exerts antibacterial activity by inhibiting penicillin-binding proteins in bacterial cell wall synthesis .
|
-
- HY-122309
-
|
|
Antibiotic
|
Infection
|
|
A-71497 is the 3-formyl derivative of the antibiotic Tosufloxacin (HY-B1802). A-71497 can produce high plasma levels of tosufloxacin upon both oral and subcutaneous administration to mice .
|
-
- HY-123598
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Corynecin III is a Chloramphenicol (HY-B0239)-like antibiotic, which is found in Corynebacterium. Corynecin III inhibits the growth of Gram-positive and Gram-negative bacteria with MIC values of 2.6-83 μg/mL .
|
-
- HY-125707
-
|
MCH 210
|
Proton Pump
Antibiotic
|
Infection
|
|
Concanamycin B is a macrolide antibiotic, which can inhibit the cavitation type H+-ATPases, and the IC50 value is 5 nM .
|
-
- HY-123635
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Nybomycin, an antibiotic, exhibits antiphage and antibacterial properties. Nybomycin binds to DNA and induces a unique morphological change to mycobacterial bacilli leading the bacterial cell death .
|
-
- HY-B0507R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfathiazole (Standard) is the analytical standard of Sulfathiazole. This product is intended for research and analytical applications. Sulfathiazole, an organosulfur compound, is used as a short-acting sulfonamide antibiotic .
|
-
- HY-169175
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
CN-CC-861 is a broad-spectrum antibiotic. CN-CC-861 shows antibiotic activities for susceptible and multidrug-resistant bacteria. CN-CC-861 shows potent bactericidal activity in vivo .
|
-
- HY-147359
-
|
|
Antibiotic
Apoptosis
|
Cancer
|
|
Boanmycin is an antibiotic with antitumor activity that induces cellular senescence and apoptosis .
|
-
- HY-A0246A
-
-
- HY-A0246
-
-
- HY-111019A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
SCH 34343 sodium is a potent β-lactam Antibiotic with bactericidal activity against Streptococcus pneumoniae, viridans streptococci, streptococci of groups A, B, C and G, and Str. bovis .
|
-
- HY-N10469
-
|
Phleomycin F
|
Antibiotic
|
Cancer
|
|
Bleomycin B4 (Phleomycin F) is an antibiotic. Bleomycin B4 has antitumor activity. Bleomycin B4 can be used for the research of cancer .
|
-
- HY-137324
-
|
|
Drug Metabolite
Antibiotic
|
Infection
|
|
α-Apooxytetracycline is a degradation product of Oxytetracycline (HY-B0275). Oxytetracycline is an antibiotic belonging to the tetracycline class .
|
-
- HY-121780
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Aranorosin, a potent antifungal antibiotic, has been isolated from the culture filtrate and mycelium of a strain of Pseudoarachniotus roseus Kuehn .
|
-
- HY-135285
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Rifamexil is an antibiotic Rifamycin (HY-B1907A) derivative that is active against Mycobacterium avium complex and other mycobacteria .
|
-
- HY-135393S
-
|
|
Isotope-Labeled Compounds
Bacterial
|
Infection
|
|
Sulfadimethoxypyrimidine-d4 is a deuterium labeled Sulfadimethoxypyrimidine. Sulfadimethoxypyrimidine is a sulfonamide antibiotic with a broad-spectrum antibacterial effect[1].
|
-
- HY-105267
-
|
|
Fungal
Antibiotic
|
Infection
|
|
LY 121019 is a semi-synthetic antifungal antibiotic with strong anticandida activity with MIC50 value of 0.625 μg/mL .
|
-
- HY-129034
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Ramoplanin is a broad-spectrum lipoglycodepsipeptide antibiotic derived from the Actinoplanes spp with with activity against gram-positive bacteria .
|
-
- HY-N6705
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tropodithietic acid is a sulfur-containing antibiotic produced by the marine bacterium Phaeobacter inhibens. Tropodithietic acid exhibits a strong antibiotic activity against a broad spectrum of bacteria including alpha- and gammaproteobacteria, flavobacteria and actinobacteria .
|
-
- HY-B0273
-
-
- HY-136461
-
|
Polyoxorim
|
Fungal
Antibiotic
|
Infection
|
|
Polyoxin D (Polyoxorim), a polyoxin antibiotic fungicide, is a potent chitin synthetase inhibitor .
|
-
- HY-B1459
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Dicloxacillin sodium is a β-lactam antibiotic of the penicillin family. Dicloxacillin sodium against Gram-positive bacteria. Dicloxacillin sodium is active against β-lactamase-producing organisms such as Staphylococcus aureus .
|
-
- HY-B1459A
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Dicloxacillin is a β-lactam antibiotic of the penicillin family. Dicloxacillin against Gram-positive bacteria. Dicloxacillin is active against β-lactamase-producing organisms such as Staphylococcus aureus .
|
-
- HY-P10209
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cilagicin, a dodeca-lipodepsipeptide, is a Gram-positive active antibiotic. Cilagicin has a dual polyprenyl phosphate binding mechanism that impedes resistance development .
|
-
- HY-123716
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Rubradirin B is an antibiotic, which inhibits a variety of Gram-positive bacteria and Haemophilus influenza. Rubradirin B affects the ribosome functions .
|
-
- HY-156189
-
|
|
Antibiotic
|
Infection
|
|
CcpA-IN-1 is a Staphylococcus aureus antibiotic. CcpA-IN-1 has significant bactericidal activity (MICS=460 nM) .
|
-
- HY-122328
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Flambamycin is an antibiotic found in Streptomyces hygroscopicus DS 23230 strain, active against Gram-positive and Gram-negative cocci and some Gram-positive rods. Flambamycin can be used in research on antibiotic screening .
|
-
- HY-12450
-
|
Lomondomycin
|
Antibiotic
Bacterial
|
Infection
|
|
Lomofungin is a novel antibiotic produced by Streptomyces lomondensis sp.N . Lomofungin can inhibit MBNL1-CUG RNA binding. Lomofungin has antibacterial activity .
|
-
- HY-136443
-
|
|
Antibiotic
|
Infection
|
|
4-Epitetracycline hydrochloride is an epimer of Tetracycline (HY-A0107). Tetracycline can undergo epimerization in
solution to 4-Epitetracycline hydrochloride, which shows a much lower antibiotic activity .
|
-
- HY-129269
-
|
A-68567
|
Antibiotic
Bacterial
|
Infection
|
|
Pacidamycin I (A-68567) is a nucleoside peptide antibiotic that is highly specific for Pseudomonas aeruginosa .
|
-
- HY-13952
-
|
|
Bacterial
|
Infection
|
|
TP-808 is an intermediate used in tetracycline antibiotic synthesis with antimicrobial activity. TP-808 binds to the 30S ribosome subunit of the bacteria, preventing aminoacyl-trNA from entering the A site, thereby inhibiting the extension of the protein chain. TP-808 can be used in antibiotic drug development research .
|
-
- HY-N6783
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Oligomycin C is a macrolide antibiotic produced by Streptomyces strains. Oligomycin C exhibits a strong activity against Aspergillus niger, Alternaria alternata, Botrytis cinerea and Phytophthora capsici but no activity toward bacteria .
|
-
- HY-B0337A
-
|
Sulphadimethoxine sodium
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfadimethoxine sodium (Sulphadimethoxine sodium) is a sulfonamide antibiotic used to treat many infections .
|
-
- HY-B0337
-
|
Sulphadimethoxine
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfadimethoxine (Sulphadimethoxine) is a sulfonamide antibiotic used to treat many infections .
|
-
- HY-135372
-
|
|
Drug Metabolite
|
Infection
|
|
Descarbamoyl cefuroxime is a degradation product of Cefuroxime. Descarbamoyl cefuroxime is also an intermediate for the synthesis of Cephalosporin antibiotics .
|
-
- HY-125656
-
|
Rhodosporin
|
Antibiotic
Bacterial
|
Infection
|
|
Bostrycin (Rhodosporin) is a new type of red pigment antibiotic that is primarily effective against Gram-positive bacteria .
|
-
- HY-133695
-
|
|
Drug Metabolite
|
Infection
|
|
Florfenicol amine is a metabolite of Florfenicol (HY-B1374). Florfenicol, a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases .
|
-
- HY-146646
-
|
|
Antibiotic
|
Infection
Cancer
|
|
Bleomycin A2, an antitumor antibiotic promoting DNA-degradation, is an aspartate/asparagine-β-hydroxylase (AspH) inhibitor with an IC50 of 1.47 μM .
|
-
- HY-137989A
-
|
Voriconazole oxynitride hydrochloride
|
Drug Metabolite
|
Infection
|
|
Voriconazole N-oxide (Voriconazole oxynitride) (hydrochloride) is the main metabolite of Voriconazole (HY-76200) , a widely used triazole antibiotic (fungal). Voriconazole N-oxide (hydrochloride) provides information on the patient's drug metabolism capacity .
|
-
- HY-136428R
-
|
|
Drug Metabolite
Antibiotic
|
Cancer
|
|
Desoxycarbadox (Standard) is the analytical standard of Desoxycarbadox. This product is intended for research and analytical applications. Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound .
|
-
- HY-122457
-
|
|
Antibiotic
|
Infection
|
|
Δ2,3-Doramectin is the primary pH degradation products of doramectin (HY-17035). Doramectin is a antiparasitic antibiotic .
|
-
- HY-B0322S
-
-
- HY-B0555B
-
-
- HY-W002677
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Fluoroquinolonic acid is a bacteriostatic antibiotic. Fluoroquinolonic acid has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
|
-
- HY-B0555A
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Nafcillin sodium monohydrate, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium monohydrate can be used for the research of staphylococcal infections .
|
-
- HY-113753
-
|
|
Antibiotic
|
Infection
|
|
PDF-IN-1 (compound 2) is a potential Peptide deformylase (PDF) inhibitor. PDF-IN-1 can be used for the development of new broad-spectrum antibiotics 。
|
-
- HY-W747516
-
|
|
Antibiotic
|
Infection
Cancer
|
|
Butylcycloheptylprodigiosin is the secondary metabolite produced by some bacteria, such as Streptomyces. Butylcycloheptylprodigiosin is a red-pigmented antibiotic and exhibits cytotoxicity against cancer cell MCF-7 and HDF .
|
-
- HY-A0153R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cephapirin (Standard) is the analytical standard of Cephapirin. This product is intended for research and analytical applications. Cephapirin (Cefapirin) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .
|
-
- HY-N7151
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Aurachin D is an antibiotic. Aurachin D inhibits Gram-positive bacteria and a few funguses. Aurachin D blocks NADH oxidation in beef heart submitochondrial particles .
|
-
- HY-19581
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria .
|
-
- HY-A0153AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cephapirin (sodium) (Standard) is the analytical standard of Cephapirin (sodium). This product is intended for research and analytical applications. Cephapirin sodium (Cefapirin sodium) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .
|
-
- HY-139748
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
ETX0462 is a gram-negative chemotype antibiotic. ETX0462 has potent in vitro and in vivo activity against Pseudomonas aeruginosa plus all other Gram-negative ESKAPE pathogens, Stenotrophomonas maltophilia and biothreat pathogens .
|
-
- HY-B0273A
-
-
- HY-N10174
-
|
|
Antibiotic
|
Infection
|
|
Tomaymycin is an antitumor antibiotic. Tomaymycin has antimicrobial activity against Grampositive bacteria .
|
-
- HY-125617
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
α-Lipomycin is an acyclic polyene antibiotic isolated from the gram-positive bacterium Streptomyces aureofaciens Tü117 .
|
-
- HY-A0111A
-
|
Ro15-8074/001; Deacetoxycefotaxime sodium
|
Antibiotic
Bacterial
|
Infection
|
|
Cefetamet sodium is a cephalosporin antibiotic. Cefetamet sodium has the potential for the research of both upper and lower community-acquired respiratory tract infections .
|
-
- HY-106681
-
|
Fungichromin; Pentamycin; Cogomycin
|
Antibiotic
Fungal
|
Cancer
|
|
Lagosin (Fungichromin) is a polyene macrolide antibiotic. Lagosin has demonstrated broad-spectrum antifungal activity and is impervious to agent resistance .
|
-
- HY-A0111
-
|
Ro 15-8074; Deacetoxycefotaxime
|
Antibiotic
Bacterial
|
Infection
|
|
Cefetamet is a cephalosporin antibiotic. Cefetamet has the potential for the research of both upper and lower community-acquired respiratory tract infections .
|
-
- HY-123321
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sakyomicin A is an antibiotic isolated from Actinomycete strain M-53. Sakyomicin A is active against Gram-positive bacteria .
|
-
- HY-B0273S
-
|
|
Bacterial
|
Infection
|
|
Sulfadiazine-d4 is a deuterium labeled Sulfadiazine. Sulfadiazine is a sulfonamide antibiotic used for the treatment of toxoplasmosis[1][2].
|
-
- HY-122071
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Bicyclomycin is an antibiotic. Bicyclomycin has anti-Bacterial activity against Gram-negative bacteria except Proteus and Pseudomonas aeruginosa .
|
-
- HY-B1418
-
|
CL-298741; YTR-830H
|
Beta-lactamase
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Tazobactam (CL-298741) is a potent β-lactamases inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research .
|
-
- HY-A0162
-
|
|
Bacterial
|
Infection
|
|
Quinupristin is a streptogramin antibiotic. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits .
|
-
- HY-P10721
-
|
|
Antibiotic
Bacterial
|
Infection
|
Plectasin is a peptide antibiotic derived from saprophytic fungi. Plectasin can kill pneumococcus in vitro. Plectasin can alleviate experimental peritonitis and pneumonia caused by pneumococcus in mice .
|
-
- HY-A0162A
-
|
|
Bacterial
|
Infection
|
|
Quinupristin mesylate is a streptogramin antibiotic. Quinupristin mesylate blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits .
|
-
- HY-135397
-
|
(R)-PNU-100766
|
Drug Metabolite
|
Infection
|
|
(R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis .
|
-
- HY-119789
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Albofungin (Antibiotic P-42-1) is isolated from the culture filtrate of Actinomyces tumemacerans strain INMI.P-42. Albofungin shows highly active on a wide variety of gram-positive bacteria and fungi. Albofungin shows cytotoxic to HeLa cell cultures and exhibited antitumor activity on EHRLICH ascites tumor in mice.
|
-
- HY-117778
-
|
|
Enolase
Bacterial
Antibiotic
|
Infection
Cancer
|
|
SF2312, a natural phosphonate antibiotic (Antibiotic), is a highly potent Enolase inhibitor with IC50s of 37.9 nM and 42.5 nM for human recombinant ENO1 and ENO2, respectively. SF2312 is active against bacteria under anaerobic conditions .
|
-
- HY-N11422
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Mycaminosyltylonolide is a potent antibiotic. Mycaminosyltylonolide shows antibacterial activity. Mycaminosyltylonolide inhibits luciferase synthesis .
|
-
- HY-N7784
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Liriodenine methiodide is an antibiotic that is active against C. albicans and S. cereuisiae with antimicrobial activities .
|
-
- HY-P3511
-
|
|
Bacterial
|
Infection
|
|
Friulimicin D, a lipopeptide antibiotic, like Friulimicin B, is isolated from the actinomycete Actinoplanes friuliensis .
|
-
- HY-W048303
-
|
|
Antibiotic
|
Infection
Cancer
|
|
L-Azatyrosine is an antitumor antibiotic isolated from Streptomyces chibaensis. L-Azatyrosine can restore normal phenotypic behavior to transformed cells bearing oncogenic Ras genes .
|
-
- HY-136502
-
|
SQ-28429
|
Antibiotic
Bacterial
|
Infection
|
|
(E)-Aztreonam (SQ-28429) is a monocyclic beta-lactam antibiotic. (E)-Aztreonam has the potential for the research of infections caused by gram-negative pathogens .
|
-
- HY-152965
-
-
- HY-114938
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Fumaramidmycin is an antibiotic found in Streptomyces kurssanovii NR-7GG1. Fumaramidmycin shows an antimicrobial activity against both Gram-positive and Gram-negative bacteria .
|
-
- HY-122306
-
|
Mycotrienin II
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Ansatrienin B (Mycotrienin II) is an ansamycin antibiotic isolated from Streptomyces. Ansatrienin B is active against fungi and yeasts, but inactive against bacteria.Ansatrienin B displays antitumor antibiotic activity and can be used as an ADC Toxin .
|
-
- HY-122350
-
|
SF-2052 sulfate
|
Antibiotic
|
Infection
|
|
Dactimicin sulfate (SF-2052 sulfate) is an antibiotic produced by Dactylosporangium matsuzakiense and belongs to the fortimicin antibiotic family. Dactimicin sulfate is an aminoglycoside antibiotic containing a carboximido group and inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria. Dactimicin sulfate can be used in research on infections caused by sensitive bacteria .
|
-
- HY-128780
-
|
SPR206
|
Bacterial
|
Infection
Cancer
|
|
Upleganan (SPR206), a polymyxin analogue, and shows antibiotic activity against multidrug resistant Gram-negative pathogen. The MIC values of Upleganan against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301 are both 0.125 mg/L .
|
-
- HY-113799
-
-
- HY-146199
-
|
|
Bacterial
|
Infection
|
|
Antibacterial agent 108 (Compound 1h) is a potent antibacterial agent with a MIC of both 3 μM against MRSA and antibiotic resistance strains .
|
-
- HY-N8386
-
|
|
Antibiotic
|
Infection
Cancer
|
|
Berkeleylactone F is an antibiotic macrolide compound. Berkeleylactone F showed modest inhibition of CCRF-CEM leukemia cells .
|
-
- HY-W743988
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cilastatin ammonium salt is an antibiotic that is relatively effective against Gram-positive cocci with a half-life of 3-4 h .
|
-
- HY-147429A
-
|
Abx MCP TFA; RG6006 TFA
|
Antibiotic
Bacterial
|
Infection
|
|
Zosurabalpin TFA is a tethered macrocyclic peptide antibiotic, acting specifically on A. baumannii. Zosurabalpin TFA inhibits lipopolysaccharide-transport .
|
-
- HY-P2363
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Leucinostatin K is a peptide antibiotic with anti-gram-positive bacterial and fungal effects, which is found in Paecilomyces lilacinus .
|
-
- HY-B1128B
-
|
Cephamandole lithium
|
Antibiotic
Bacterial
|
Infection
|
|
Cefamandole (Cephamandole) lithium is a second-generation broad-spectrum cephalosporin antibiotic with antibacterial activity. Cefamandole lithium breaks down in the body and then releases free NMTT, which can lead to low prothrombinemia .
|
-
- HY-B1459AR
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Dicloxacillin (Standard) is the analytical standard of Dicloxacillin. This product is intended for research and analytical applications. Dicloxacillin is a β-lactam antibiotic of the penicillin family. Dicloxacillin against Gram-positive bacteria. Dicloxacillin is active against β-lactamase-producing organisms such as Staphylococcus aureus .
|
-
- HY-A0248B
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Polymyxin B2 is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 can be used in antibiotic development and treatment of drug-resistant strains .
|
-
- HY-117660
-
|
U-10149
|
Antibiotic
Bacterial
|
Infection
|
|
Lincomycin, a lincosamide antibiotic, is an antimicrobial agent used for the research of Gram-positive bacteria infections .
|
-
- HY-16473
-
|
Aldesulfone disodium
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
|
Sulfoxone (Aldesulfone) disodium is an orally active sulphonamide antibiotic that is used against leprosy. Sulfoxone disodium can also be used in study of dermatitis herpetiformis .
|
-
- HY-126780
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Nikkomycin N is a nucleoside antibiotic, which is initially produced by Streptomyces tendae. Nikkomycin N exhibits fungicidal and insecticidal properties through inhibition of chitin synthesis .
|
-
- HY-W127442
-
|
Ethyl 2-Ethylbutyrate
|
Bacterial
|
Others
|
|
Etzadroxil (Ethyl 2-Ethylbutyrate) is a volatile ester compound. Sulopenem Etzadroxil is an orally available ester proagent form of Sulopenem, an antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria .
|
-
- HY-170609
-
|
|
Bacterial
|
Infection
|
|
Antimicrobial agent-36 (Compound 8b) is an antimicrobial agent that significantly inhibits the level of DNA gyrase, with an IC50 value of 4.56 µM. Antimicrobial agent-36 can also be used for the preparation of nanopharmaceutical formulations, for the research and development of novel antibiotics .
|
-
- HY-122783
-
|
|
Antibiotic
|
Cancer
|
|
Isogambogic acid is an antibiotic and anti-cancer agent which efficiently elicit cell death in LLC and SK-LU-1 within a low micromolar range with IC50s of 2.26 μM and 2.02 μM. Isogambogic acid can be used for cancer research .
|
-
- HY-125060
-
-
- HY-125419
-
|
|
Antibiotic
Parasite
Bacterial
|
Infection
|
|
Amythiamicin B is a trisubstituted pyridine thiopeptide with antibiotic properties against Gram-positive bacteria and activity against Plasmodium falciparum .
|
-
- HY-B0337S1
-
|
Sulphadimethoxine-d6
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfadimethoxine-d6 is the deuterium labeled Sulfadimethoxine. Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections[1].
|
-
- HY-126850
-
|
|
EGFR
|
Cancer
|
|
4-Epidoxycycline is a liver metabolite of the antibiotic doxycycline (doxycycline, HY-N0565) and doesn't have antibiotic properties in mice. 4-Epidoxycycline’s ability to regulate HER2 gene expression in vitro and in live mouse models is similar to that of doxycycline, and it shows comparable high efficacy in tumor tissues, achieving over 95% tumor regression rates .
|
-
- HY-A0248C
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Polymyxin B2 Sulfate is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 Sulfate kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 Sulfate can be used in antibiotic development and treatment of drug-resistant strains .
|
-
- HY-P1926
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
A-54556A (ADEP 1) is an acyldepsipeptide (ADEP) antibiotic. A-54556A shows antibacterial activity against a broad range of Gram-positive bacteria .
|
-
- HY-B0213
-
|
Sulfametoxydiazine; 5-Methoxysulfadiazine
|
Antibiotic
Bacterial
|
Infection
|
|
Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis .
|
-
- HY-N12228
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Phenelfamycin E is an elfamycin-type antibiotic and is active against Gram-positive anaerobes, including Clostridium difficile. Phenelfamycin E can be used for anti-bacteria research .
|
-
- HY-145158
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Temocillin, a 6-alpha-methoxy penicillin derivative, is a semisynthetic beta-lactam antibiotic with a spectrum of activity against most aerobic Gram-negative bacteria .
|
-
- HY-161300
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Antibacterial agent 191 (compound 11a) is a potent semi-synthetic antibiotic. Antibacterial agent 191 exhibits preferable metabolic stability .
|
-
- HY-P1699
-
-
- HY-124334
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
L-161240 is an antibiotic, which exhibits antibacterial activity against Escherichia coli, through inhibition of LpxC enzyme (Ki is 50 nM) .
|
-
- HY-150520
-
|
|
Antibiotic
|
Infection
Cancer
|
|
Neomycin is an aminoglycoside antibiotic. Neomycin can be used for the research of external or internal bacterial infections, is primarily administered in veterinary medicine as a sulfate salt .
|
-
- HY-B0974
-
|
Meticillin sodium
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
|
|
Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation .
|
-
- HY-A0107
-
|
MK-801 maleate
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections .
|
-
- HY-W653871
-
|
|
Isotope-Labeled Compounds
|
Infection
|
|
Florfenicol amine-d3 is deuterated labeled Florfenicol amine. Florfenicol amine is a metabolite of Florfenicol (HY-B1374). Florfenicol, a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases .
|
-
- HY-B0273R
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Sulfadiazine (Standard) is the analytical standard of Sulfadiazine. This product is intended for research and analytical applications. Sulfadiazine is a sulfonamide antibiotic with antimalarial activity. Sulfadiazine can be used for toxoplasmosis research .
|
-
- HY-116168
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aldecalmycin is an antibiotic showing antimicrobial activities against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MICs values of 6.25-25 μg/mL .
|
-
- HY-122414
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Phosalacine is a phosphorouscontaining tripeptide herbicidal antibiotic that can be isolated from soil isolate Kitasatosporia phosalacinea KA-338. Phosalacine also shows antibacterial and antifungal activity .
|
-
- HY-B0395C
-
|
DU6859a hydrate
|
Bacterial
Antibiotic
|
Infection
|
|
Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections .
|
-
- HY-W714002
-
|
|
HIV
Bacterial
|
Infection
|
|
Feglymycin is a HIV replication inhibitor. Feglymycin is also an antibiotic peptide that has antibacterial activity (MIC: 32-64 μg/mL for Staphylococcus aureus) .
|
-
- HY-A0147
-
|
OPC-17116; dl-Grepafloxacin
|
Antibiotic
Bacterial
|
Infection
|
|
Grepafloxacin (OPC-17116) is an oral actively fluoroquinolone antibiotic with potent activity against community-acquired respiratory pathogens including Streptococcus pneumonia. Grepafloxacin has high tissue penetration and a promising pharmacodynamic profile .
|
-
- HY-136590
-
|
|
Antibiotic
|
Others
|
|
2-Nitrosopyridine is a nitroso compound that can be used to synthesize antibiotics. 2-Nitrosopyridine can be used as a Click or Diels-Alder derivatization reagent and an excellent dienophile .
|
-
- HY-B0467
-
|
Amoxycillin sodium
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Amoxicillin (Amoxycillin) sodium is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin sodium inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
|
-
- HY-B0467A
-
|
Amoxycillin
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Amoxicillin (Amoxycillin) is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
|
-
- HY-136443R
-
|
|
Antibiotic
|
Infection
|
|
4-Epitetracycline (hydrochloride) (Standard) is the analytical standard of 4-Epitetracycline (hydrochloride). This product is intended for research and analytical applications. 4-Epitetracycline hydrochloride is an epimer of Tetracycline (HY-A0107). Tetracycline can undergo epimerization in
solution to 4-Epitetracycline hydrochloride, which shows a much lower antibiotic activity .
|
-
- HY-N0465
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Olaquindox, a quinoxalin derivative, is an orally active antibiotic. Olaquindox stimulates growth and decreases intestinal mucosal immunity of piglets .
|
-
- HY-W715444
-
-
- HY-A0147A
-
|
OPC-17116 hydrochloride; dl-Grepafloxacin hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Grepafloxacin (OPC-17116) hydrochloride is an oral actively fluoroquinolone antibiotic with potent activity against community-acquired respiratory pathogens including Streptococcus pneumonia. Grepafloxacin hydrochloride has high tissue penetration and a promising pharmacodynamic profile .
|
-
- HY-N15179
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Minosaminomycin is an antibiotic containing myo-inosamine that can be extracted from Streptomyces No. MA514A1. Minosaminomycin exerts antimicrobial activity against Mycobacterium smegrnatis ATCC 607 and Mycobacterium phlei (MIC= 1.56/6.25 mcg/mL) .
|
-
- HY-P10518
-
|
|
Bacterial
|
Infection
|
|
Anoplin is an antimicrobial peptide found in the venom of the solitary wasp (Anoplius samariensis). Anoplin exhibits antimicrobial activity against a wide range of bacteria, including both gram-positive and gram-negative bacteria. Anoplin can be used in the development of antibiotics .
|
-
- HY-117108
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Nocardicin A is a beta-lactam antibiotic with selective antibacterial activity. Nocardicin A has moderate antibacterial activity against a broad spectrum of Gram-negative bacteria including Proteus and Pseudomonas; it has no inhibitory effect on Staphylococcus, Mycobacterium, fungi, and yeast .
|
-
- HY-139398
-
TBI-223
1 Publications Verification
|
Antibiotic
Bacterial
|
Infection
|
|
TBI-223 is an orally bioavailable oxazolidinone antibiotic and an antimicrobial. TBI-223 shows activity against Mycobacterium tuberculosis (Mtb) .
|
-
- HY-135562
-
-
- HY-N10495
-
|
|
Antibiotic
Bacterial
Topoisomerase
|
Infection
|
|
Seconeolitsine, an antibiotic, and is an inhibitor of targeting topoisomerase I (TopA). Seconeolitsine also is a new antimicrobial agent that can inhibit S. pneumoniae growth. Seconeolitsine can inhibit TopA relaxation activity with an IC50 value of 17 μM. Seconeolitsine can be used for the research of S. pneumoniae infections resistant to other antibiotics .
|
-
- HY-N11407
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Bagougeramine B is an orally active nucleoside antibiotic with antimicrobial activity, which is found in Bacillus circulans. Bagougeramine B inhibits the growth of Gram-positive and Gram-negative bacteria and some fungi .
|
-
- HY-N12258
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aranciamycin A is an anthracyclic antibiotic and can be isolated from Streptomyces. Aranciamycin A shows antibacterial activity against M. bovis and B. subtilis with the MIC values of 30 and 7.5 µM, respectively .
|
-
- HY-12396
-
|
2-Aminothiazole; 2-Thiazolylamine
|
Bacterial
Fungal
Virus Protease
|
Infection
|
|
Aminothiazole (2-Aminothiazole), a typical heterocyclic amine, is a precursor for the synthesis of biologically active molecules including sulfur agents, biocides, fungicides, antibiotics, dyes and chemical reaction accelerators .
|
-
- HY-B0529A
-
|
Sodium azlocillin
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Azlocillin sodium salt (Sodium azlocillin), a semisynthetic penicillin, is a broad spectrum β-lactam antibiotic. Azlocillin sodium salt shows antipseudomonal activity, and also potent against the malarial parasite Plasmodium falciparum .
|
-
- HY-19581R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Baquiloprim (Standard) is the analytical standard of Baquiloprim. This product is intended for research and analytical applications. Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria .
|
-
- HY-133695R
-
|
|
Drug Metabolite
|
Infection
|
|
Florfenicol amine (Standard) is the analytical standard of Florfenicol amine. This product is intended for research and analytical applications. Florfenicol amine is a metabolite of Florfenicol (HY-B1374). Florfenicol, a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases .
|
-
- HY-116271
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sperabillin C is an antibacterial antibiotic with activity against both Gram-negative and Gram-positive bacteria, including resistant strains of Pseudomonas aeruginosa and Staphylococcus aureus .
|
-
- HY-B0337AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfadimethoxine (sodium) (Standard) is the analytical standard of Sulfadimethoxine (sodium). This product is intended for research and analytical applications. Sulfadimethoxine sodium (Sulphadimethoxine sodium) is a sulfonamide antibiotic used to treat many infections .
|
-
- HY-B0555
-
|
|
Beta-lactamase
Antibiotic
Bacterial
|
Infection
|
|
Nafcillin, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin exhibits bactericidal activity, and can be used for the research of staphylococcal infections .
|
-
- HY-150036
-
|
|
Antibiotic
Cholecystokinin Receptor
|
Cancer
|
|
Anthramycin, a member of the pyrolobenzodiazepine (PBD) family, is a potent antibiotic. Anthramycin has potent antitumor activity. Anthramycin can act as an potent antagonist of cholecystokinin in the central nervous system in mice .
|
-
- HY-123886
-
|
|
Antibiotic
|
Cancer
|
|
Aranciamycin (Compound 1) is an anthracycline antibiotic with collagenase inhibitory activity (IC503.7*10-7M). Aranciamycin can be used to inhibit DNA synthesis in tumor cells .
|
-
- HY-148576
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Antibacterial agent 136 (compound 3) is an antibiotic of oxadiazolones. Antibacterial agent 136 have high antibacterial potency against Staphylococcus aureus (MRSA) with a MIC50 value of 0.8 μM .
|
-
- HY-W002677R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Fluoroquinolonic acid (Standard) is the analytical standard of Fluoroquinolonic acid. This product is intended for research and analytical applications. Fluoroquinolonic acid is a bacteriostatic antibiotic. Fluoroquinolonic acid has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
|
-
- HY-B0467C
-
|
Amoxycillin arginine
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Amoxicillin (Amoxycillin) arginine is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin arginine inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
|
-
- HY-B0467B
-
|
Amoxycillin trihydrate
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Amoxicillin (Amoxycillin) trihydrateis an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin trihydrateis inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
|
-
- HY-B0555BR
-
|
|
Beta-lactamase
Antibiotic
Bacterial
|
Infection
|
|
Nafcillin (sodium) (Standard) is the analytical standard of Nafcillin (sodium). This product is intended for research and analytical applications. Nafcillin sodium, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium can be used for the research of staphylococcal infections .
|
-
- HY-B0555AR
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Nafcillin (sodium monohydrate) (Standard) is the analytical standard of Nafcillin (sodium monohydrate). This product is intended for research and analytical applications. Nafcillin sodium monohydrate, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium monohydrate can be used for the research of staphylococcal infections .
|
-
- HY-P5459
-
|
|
Bacterial
Elastase
|
Infection
|
|
Elafin,also known as elafin-specific inhibitor (ESI) or skin anti-leucoprotease (SKALP), is a low molecular weight inhibitor of human neutrophil elastase (HNE) and proteinase 3 in lung. Elafin is antibiotic against Pseudomonas aeruginosa and Staphylococcus aureus .
|
-
- HY-B1418R
-
|
|
Beta-lactamase
Antibiotic
Bacterial
|
Infection
|
|
Tazobactam (Standard) is the analytical standard of Tazobactam. This product is intended for research and analytical applications. Tazobactam (CL-298741) is a potent β-lactamases inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research .
|
-
- HY-126490
-
|
|
Bacterial
Antibiotic
DNA/RNA Synthesis
|
Infection
Cancer
|
|
Phleomycin is an anticancer glycopeptide antibiotic found in Streptomyces verticillus, which cause DNA cleavage. Phleomycin binds and intercalates DNA to damage the integrity of the double helix, which is similar to Bleomycin (HY-17565A) .
|
-
- HY-B0337S
-
|
Sulphadimethoxine-d4
|
Bacterial
|
Infection
|
|
Sulfadimethoxine-d4 is a deuterium labeled Sulfadimethoxine (Sulphadimethoxine). Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections[1].
|
-
- HY-B0643
-
|
LY237216
|
Bacterial
Antibiotic
|
Infection
|
|
Dirithromycin (LY237216), a derivative of Erythromycin, is a potent and orally active semi-synthetic macrolide antibiotic. Dirithromycin is active against gram-positive bacteria, Legionella spp., Helicobacter pylori, and Chlamydia trachomatis .
|
-
- HY-A0111R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cefetamet (Standard) is the analytical standard of Cefetamet. This product is intended for research and analytical applications. Cefetamet is a cephalosporin antibiotic. Cefetamet has the potential for the research of both upper and lower community-acquired respiratory tract infections .
|
-
- HY-136457
-
|
|
Drug Metabolite
|
Others
|
|
2-NP-AHD is a 2-nitrophenyl derivative of AHD (a metabolite of nitrofurans type of antibiotics), can be used as indicator of the illegal usage of nitrofuran agents .
|
-
- HY-N10470
-
|
Pingyangmycin
|
Apoptosis
|
Infection
Inflammation/Immunology
Cancer
|
|
Bleomycin A5 (Pingyangmycin) is an orally active glycopeptide antibiotics. Bleomycin A5 has a role as an antineoplastic agent, an apoptosis inducer and a bacterial metabolite .
|
-
- HY-115249
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa .
|
-
- HY-W009168
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Tazobactam sodium is an antibiotic of the beta-lactamase inhibitor class. Ceftolozane combines with Tazobactam, extends the activity of ceftolozane against many ESBL-producing Enterobacteriaceae and some Bacteroides spp..
|
-
- HY-137801
-
|
|
Parasite
|
Infection
|
|
Sesquicillin A is an insecticidal antibiotic, a fungal metabolite isolated from white plantain. Sesquicillin A inhibits the growth of A. salina brine shrimp with the MIC value of 6.25 µg/mL .
|
-
- HY-34588
-
|
D-(-)-4-Hydroxyphenylglycine; 4-Hydroxy-D-phenylglycine
|
Antibiotic
|
Others
|
|
D-4-Hydroxyphenylglycine (D-(-)-4-Hydroxyphenylglycine) is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Amoxicillin (HY-B0467A) and Cefadroxil (HY-B1190) .
|
-
- HY-B1327A
-
|
7-Chlorotetracycline
|
Bacterial
Antibiotic
Parasite
|
Infection
Inflammation/Immunology
|
|
Chlortetracycline (7-Chlorotetracycline) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline is also a antibiotic that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline is a specific and potent calcium ionophore antibiotic, inhibiting binding of aminoacyl-tRNA to ribosomes .
|
-
- HY-B1327
-
|
7-Chlorotetracycline hydrochloride
|
Bacterial
Antibiotic
Parasite
|
Infection
Inflammation/Immunology
|
|
Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline hydrochloride is also a antibiotic that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline hydrochloride is a specific and potent calcium ionophore antibiotic, inhibiting binding of aminoacyl-tRNA to ribosomes .
|
-
- HY-P2223
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Hypeptin is a cyclo-deposited peptide antibiotic produced by Lysobacter sp.K5869. Hypeptin blocks bacterial cell wall biosynthesis by binding to multiple undecaprenyl pyrophosphate-containing biosynthesis intermediates, forming a stoichiometric 2:1 complex. Hypeptin has antibacterial activity .
|
-
- HY-135397R
-
|
|
Drug Metabolite
|
Infection
|
|
(R)-Linezolid (Standard) is the analytical standard of (R)-Linezolid. This product is intended for research and analytical applications. (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis .
|
-
- HY-19137
-
|
KW 2189 free base
|
Antibiotic
|
Infection
Cancer
|
|
Pibrozelesin (KW 2189 free base) is the derivative of antibiotic Duocarmycin B2. Pibrozelesin exhibits antitumor activity, inhibits proliferation of cell H69 with an IC50 of 1.9 μM. Pibrozelesin induces the DNA strand breaks upon activation via carboxyl esterase .
|
-
- HY-B0273AR
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Sulfadiazine (sodium) (Standard) is the analytical standard of Sulfadiazine (sodium). This product is intended for research and analytical applications. Sulfadiazine sodium is a sulfonamide?antibiotic with antimalarial activity. Sulfadiazine can be used for toxoplasmosis research .
|
-
- HY-N14922
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Nikkomycin Lx is an antibiotic that can be extracted from Streptomyces tendae TU901. Nikkomycin Lx exhibits anti-Candida Albicans activity and can be utilized in relevant research .
|
-
- HY-19647
-
|
FCE 22891; RIPM-AC; Ritipenem acetoxymethyl ester
|
Beta-lactamase
Antibiotic
Bacterial
|
Infection
|
|
Ritipenem acoxil (FCE 22891; RIPM-AC) is an oral active beta-lactamase antibiotic and can be used for study of bacterial pneumonia .
|
-
- HY-15993
-
|
AZD2563; AZD5847
|
Antibiotic
|
Infection
|
|
Posizolid (AZD2563), an oxazolidinone antibiotic, is developed by AstraZeneca for the study of bacterial infections. Posizolid shows very good anti-mycobacterial activity .
|
-
- HY-B1267
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery .
|
-
- HY-128502
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Nifurtoinol is a nitrofuran-derivative antibiotic with antibacterial effects. Nifurtoinol can be used for the research of urinary tract infections .
|
-
- HY-B0974R
-
|
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
|
|
Methicillin (sodium salt) (Standard) is the analytical standard of Methicillin (sodium salt). This product is intended for research and analytical applications. Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation .
|
-
- HY-118448
-
|
|
Antibiotic
Bacterial
Fungal
Parasite
|
Infection
|
|
2,4-Diacetylphloroglucinol, produced by some isolates of the beneficial bacterium Pseudomonas fluorescens, is a potent antibiotic. 2,4-Diacetylphloroglucinol is active against numerous organisms, including plants, fungi, viruses, bacteria, and nematodes .
|
-
- HY-111190
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Thiotropocin is a tropothione Antibiotic with antibacterial activities against Gram-positive and Gram-negative bacteria, some phytopathogens and mycoplasma. Thiotropocin causes morphological changes of Proteus mirabilis and Escherichia coli .
|
-
- HY-17591
-
|
Benzylpenicillin potassium
|
Antibiotic
Bacterial
|
Infection
|
|
Penicillin G potassium is a fast-acting penicillin family antibiotic. Penicillin G potassium can be used for the research of bacterial infections that affect the blood, heart, lungs, joints, and genital areas .
|
-
- HY-136817
-
|
OM173-αA; Nanaomycin A methyl ester
|
Antibiotic
|
Infection
|
|
Nanaomycin αA (OM173-αA) is an antibiotic with antimicrobial activity. Nanaomycin αA can be isolated from a fermentation broth of Streptomyces hebeiensis derived from lichen .
|
-
- HY-128780B
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
SPR206 acetate is a polymyxin analog with antibiotic activity against Gram-negative pathogens, including multidrug-resistant (MDR) variants. SPR206 acetate has an anti-bacterial infection effect by interacting with the bacterium’s outer membrane. The MIC values of SPR206 acetate against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301 are both 0.125 mg/L .
|
-
- HY-108913
-
|
|
Beta-lactamase
Antibiotic
Bacterial
|
Infection
|
|
Nitrocefin is a highly activated, chromogenic cephalosporin derivative. Nitrocefin is a chromogenic β-lactamase substrate. Nitrocefin undergoes a distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics .
|
-
- HY-120242
-
|
|
Antibiotic
|
Infection
|
|
N-(3-Oxobutanoyl)-L-homoserine lactone (3-oxo-C4-HSL) is a carbapenem antibiotic biosynthesis autoregulator in Erwinia carotovora ATCC 39048. N-(3-Oxobutanoyl)-L-homoserine lactone induces expression of rhiI in R. leguminosarum .
|
-
- HY-116571
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
RU44790 is a monocyclic beta-lactam antibiotic that exerts potent activity against gram-negative bacteria and is highly resistant to hydrolysis by various beta-lactamases. RU44790 can be utilized in anti-bacteria research .
|
-
- HY-138179
-
|
|
Bacterial
|
Infection
|
|
7-APRA is a semi-synthetic intermediate of cephalosporin antibiotics. 7-APRA has antibacterial activity and is mainly used in the synthesis of other Cefaclor (HY-B0198) and Cefprozil (HY-B0458A) .
|
-
- HY-B0395CR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sitafloxacin (hydrate) (Standard) is the analytical standard of Sitafloxacin (hydrate). This product is intended for research and analytical applications. Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections .
|
-
- HY-117430
-
-
- HY-120838
-
|
Koningic acid
|
Caspase
|
Infection
Cancer
|
|
Heptelidic acid (Koningic acid) is a sesquiterpene antibiotic . Heptelidic acid inhibits Etoposide-induced apoptosis via downregulation of caspases . Koningic acid (KA) is a specific GAPDH inhibitor with an IC50of 90 μM .
|
-
- HY-136068
-
|
|
Antibiotic
Bacterial
Autophagy
|
Infection
Cancer
|
|
DCAP is a broad-spectrum antibiotic targeting the membranes of both Gram-positive and Gram-negative bacteria. DCAP blocks autophagy at the late stages by preventing autophagolysosome maturation and interrupting the autophagic flux .
|
-
- HY-124438
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Herbicidin A is an adenosine-derived nucleoside antibiotic, but also is a herbicide against dicotyledonous plants. Herbicidin A can be isolated from Streptomyces scopuliridis M40 .
|
-
- HY-121300
-
|
(-)-TAN2162
|
Antibiotic
Bacterial
Endothelin Receptor
CGRP Receptor
|
Infection
Cancer
|
|
Kendomycin ((−)-TAN 2162) is a polyketide antibiotic with remarkable antibacterial and cancer cells cytotoxic activities. Kendomycin tends to be bacteriostatic rather than bactericidal and inhibits the growth of the methicillin-resistant Staphylococcus aureus (MRSA) strain COL at a low concentration (MIC of 5 μg/mL). Kendomycin is a potent antagonist of the endothelin receptor and a calcitonin receptor agonist which plays its role as an anti-osteoporotic agent .
|
-
- HY-D2437
-
|
|
Fluorescent Dye
Antibiotic
|
Cardiovascular Disease
Cancer
|
|
DOX-PEG-Cy3 (Doxorubicin-PEG-Cy3) is a Cy3 (HY-D0822) labeled DOX-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. DOX is a broad-spectrum anthracycline antibiotic with cytotoxic properties .
|
-
- HY-108913R
-
|
|
Beta-lactamase
Antibiotic
|
Infection
|
|
Nitrocefin (Standard) is the analytical standard of Nitrocefin. This product is intended for research and analytical applications. Nitrocefin is a chromogenic β-lactamase substrate that undergoes a distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics .
|
-
- HY-A0107R
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Tetracycline (Standard) is the analytical standard of Tetracycline. This product is intended for research and analytical applications. Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections .
|
-
- HY-125414
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Lydicamycin is an antibiotic isolated from the fermentation broth of an actinomycete strain identified as Streptomyces lydicus. Lydicamycin is active against Gram-positive bacteria and a certain yeast, but inactive against Gram-negative bacteria .
|
-
- HY-B0522C
-
|
L-(+)-α-Aminobenzylpenicillin
|
Antibiotic
|
Infection
|
|
L-(+)-Ampicillin (L-(2S) ampicillin) is the L-isomer of Ampicillin (HY-B0522). Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .
|
-
- HY-B0213R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sulfameter (Standard) is the analytical standard of Sulfameter. This product is intended for research and analytical applications. Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis .
|
-
- HY-N7151R
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Kasugamycin (hydrochloride) (Standard) is the analytical standard of Kasugamycin (hydrochloride). This product is intended for research and analytical applications. Kasugamycin hydrochloride (Ksg hydrochloride) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin hydrochloride (Ksg hydrochloride) mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation .
|
-
- HY-N1500S1
-
|
|
TRP Channel
Endogenous Metabolite
Isotope-Labeled Compounds
|
Inflammation/Immunology
|
|
Pulegone-d8 is deuterated labeled Tetracycline (HY-A0107). Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections .
|
-
- HY-149154
-
|
|
Antibiotic
|
Infection
|
|
(4S,5S,6S,12aS)-Oxytetracycline is a broad-spectrum antibiotic that can inhibit the synthesis of protein in bacteria. (4S,5S,6S,12aS)-Oxytetracycline is an important member of the bacterial aromatic polyketone family, a type of natural product with diverse structures .
|
-
- HY-131165
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
|
-
- HY-161239A
-
|
|
Antibiotic
|
Infection
Cancer
|
|
IB-96212 (compound 5) is a member of oligomycin class which can be extracted ftom the marine Micromonospora sp. L-25-ES25-008 ref. IB-96212 is an antitumor antibiotic against P-388, it also exhibits antimicrobial activity against Micrococcus luteus .
|
-
- HY-77641
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment .
|
-
- HY-117660R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Lincomycin (Standard) is the analytical standard of Lincomycin. This product is intended for research and analytical applications. Lincomycin, a lincosamide antibiotic, is an antimicrobial agent used for the research of Gram-positive bacteria infections .
|
-
- HY-B1329
-
|
Nebramycin II sulfate
|
Bacterial
Antibiotic
|
Infection
|
|
Apramycin (EBL 1003) sulfate is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin sulfate is a potential anti-drug-resistance antibiotic .
|
-
- HY-116010
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Oleandomycin is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes .
|
-
- HY-135470
-
|
P-7138
|
Antibiotic
Bacterial
|
Infection
|
|
Nifurpirinol (P-7138) is a nitroaromatic antibiotic and acts as a novel substrate for the bacterial nitroreductase (NTR) enzyme. Nifurpirinol is a more potent proagent compared to Metronidazole to trigger cell-ablation in nitroreductase expressing transgenic models .
|
-
- HY-127019
-
|
|
Potassium Channel
NOD-like Receptor (NLR)
Bacterial
Antibiotic
Pyroptosis
Wnt
β-catenin
|
Infection
Cancer
|
|
Nigericin is an antibiotic derived from Streptomyces hygroscopicus that act as a K +/H + ionophore, promoting K +/H + exchange across mitochondrial membranes. Nigericin is a NLRP3 activator. Nigericin shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt/β-catenin signals. Nigericin induces pyroptosis through caspase 1/GSDMD in TNBC .
|
-
- HY-B0467AR
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Amoxicillin (Standard) is the analytical standard of Amoxicillin. This product is intended for research and analytical applications. Amoxicillin (Amoxycillin) is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
|
-
- HY-129234
-
-
- HY-106882
-
|
MDL 62879
|
Bacterial
Antibiotic
|
Infection
|
|
GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection .
|
-
- HY-113629
-
|
D-Glucosone; D-Arabino-hexos-2-ulose
|
Drug Metabolite
|
Infection
|
|
2-Keto-D-Glucose (D-Glucosone) is a key intermediate in a secondary metabolic pathway leading to the antibiotic Cortalcerone. 2-Keto-D-Glucose is also an intermediate in the conversion of D-glucose into D-fructose. 2-Keto-D-Glucose is found in various natural sources, including fungi, algae, and shellfish .
|
-
- HY-19160
-
|
PA-1806; BMS 180680-01
|
Antibiotic
Bacterial
|
Infection
|
|
BMS-180680 (PA-1806) is an antibiotic, which exhibits a board-spectrum antibacterial activity against gram-negative bacteria. BMS-180680 inihibits Pseudomonas aeruginosa with MIC of 0.25 µg/ml. BMS-180680 exhibits resistance to hydrolysis by β-lactamases, such as TEM-2 and PSE enzymes .
|
-
- HY-113542
-
|
(+)-Blasticidin A
|
Bacterial
Antibiotic
Parasite
|
Infection
|
|
Blasticidin A ((+)-Blasticidin A) is an inhibitor of Aflatoxin production by Aspergillus parasiticus. Blasticidin A almost completely inhibits Aflatoxin production at 0.5 μM . Blasticidin A is a potent antibiotic produced by Streptomyces, inhibits Aflatoxin production without strong growth inhibition toward Aflatoxin-producing fungi .
|
-
- HY-159666
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Nystatin A1 is a polyene macrolide antifungal antibiotic that can be isolated from Streptomyces noursei. Nystatin A1 binds to ergosterol on the fungal cell membrane, increasing the permeability of the cell membrane and causing leakage of cell contents, thereby inhibiting the growth and reproduction of fungi .
|
-
- HY-B0529AR
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Azlocillin (sodium salt) (Standard) is the analytical standard of Azlocillin (sodium salt). This product is intended for research and analytical applications. Azlocillin sodium salt (Sodium azlocillin), a semisynthetic penicillin, is a broad spectrum β-lactam antibiotic. Azlocillin sodium salt shows antipseudomonal activity, and also potent against the malarial parasite Plasmodium falciparum .
|
-
- HY-A0251
-
|
Cefpodoxime acid; R 3763
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Cefpodoxime (Cefpodoxime acid) is a potent antibiotic active against gram-positive and gram-negative bacteria. Cefpodoxime inhibits the majority of cells in microbial populations. Cefpodoxime can be used for acute otitis media, sinusitis and tosillopharyngitis research .
|
-
- HY-162174
-
|
|
Beta-lactamase
Bacterial
|
Infection
|
|
MBL-IN-2 ((2R, 2R')-5αC) is an inhibitor of Metallo-β-lactamase (MBL) that can inhibit New Delhi Metallo-β-lactamase-1 (NDM-1) with an IC50 of 0.3 μM. MBL-IN-2 ((2R, 2R')-5αC) can be used for the study of resistance to β-lactam antibiotics .
|
-
- HY-B0734A
-
|
SCE-963 hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Cefotiam (SCE-963) hydrochloride is a parenteral cephalosporin antibiotic. Cefotiam hydrochloride has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
|
-
- HY-B0734
-
|
SCE-963; Cefotiam Dihydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Cefotiam (SCE-963) is a parenteral cephalosporin antibiotic. Cefotiam has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
|
-
- HY-B0734B
-
|
SCE-963 dihydrochloride hydrate
|
Antibiotic
Bacterial
|
Infection
|
|
Cefotiam (SCE-963) dihydrochloride hydrate is a parenteral cephalosporin antibiotic. Cefotiam dihydrochloride hydrate has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
|
-
- HY-A0155
-
|
|
Antibiotic
Bacterial
|
Cancer
|
|
Viomycin is a potent antibiotic against Mycobacteria. Viomycin rapidly inhibits polypeptide chain elongation when added to purified endogenous Escherichia coli polysomes actively engaged in polypeptide synthesis .
|
-
- HY-W013549
-
|
6-APA
|
Bacterial
|
Infection
|
|
6-Aminopenicillanic acid (6-APA) is an important precursor for the synthesis of -lactam antibiotics. 6-Aminopenicillanic acid is the main product of Penicillin G (PenG) hydrolyzed by penicillin acylase (PA) .
|
-
- HY-B0278
-
|
Zinc bacitracin
|
Bacterial
Antibiotic
|
Infection
|
|
Bacitracin Zinc is a complex formed by the binding of Bacitracin (HY-107193) with zinc ions. Bacitracin Zinc is an orally active polypeptide antibiotic with bactericidal properties. Bacitracin Zinc can cause DNA and deoxyribose damage, as well as improve the gut microbiota of broiler and beef cattle .
|
-
- HY-N15337
-
|
OS-4742 A1
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Vineomycin A1 (OS-4742 A1) is an antibiotic against Gram-positive bacteria, which is found in Streptomyces matensis subsp. vineus. Vineomycin A1 also shows antitumor activity in mice. Vineomycin A1 is promising for research of skin fibrosis .
|
-
- HY-126837
-
|
Spicamycin VIII
|
Antibiotic
|
Cancer
|
|
SPM VIII is a dodecanoyl analogue of spicamycin, a nucleoside antibiotic that contains fatty acids of various chain lengths. SPM VIII exhibits potent antitumor activity against the human gastric cancer SC-9 xenograft model .
|
-
- HY-N13154
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Malolactomycin C (compound 1) is a macrolide antifungal antibiotic isolated from Streptomyces strain KP-3144. Malolactomycin C is an effective inhibitor of Botrytis cinerea and thus controls a variety of plant diseases including gray mold .
|
-
- HY-N13278
-
|
2-Acetyl-2-decarboxamidooxytetracycline
|
Antibiotic
|
Others
|
|
2-Acetyl-2-decarboxamidotetracycline (2-Acetyl-2-decarboxamidooxytetracycline) is an antibiotic of the tetracycline type. 2-Acetyl-2-decarboxamidotetracycline shows an ultraviolet absorption spectrum which is identical with that of tetracycline or of 5-oxytetracycline above 300 mμ, a region characteristic of the BCD-ring system .
|
-
- HY-128423
-
|
Acetylisovaleryltylosin tartrate
|
Antibiotic
Bacterial
NF-κB
Apoptosis
|
Infection
Inflammation/Immunology
|
|
Tylvalosin (Acetylisovaleryltylosin) tartrate is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin tartrate is an antiviral agent useful in studying PRRSV infection. Tylvalosin tartrate induces apoptosis. Tylvalosin tartrate also has anti-inflammatory activity, relieves oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation .
|
-
- HY-129306
-
|
|
Antibiotic
Bacterial
|
Inflammation/Immunology
|
|
Gilvocarcin M is an antibiotic and can be isolated from S. gilvotanareus. Gilvocarcin M is active against S. aureus at a concentration of 32 µg/ml and inhibits growth of KB cells with the IC50 of 0.52 µg/ml. Gilvocarcin M intercalates into bacteriophage PM2 DNA .
|
-
- HY-B0643R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Dirithromycin (Standard) is the analytical standard of Dirithromycin. This product is intended for research and analytical applications. Dirithromycin (LY237216), a derivative of Erythromycin, is a potent and orally active semi-synthetic macrolide antibiotic. Dirithromycin is active against gram-positive bacteria, Legionella spp., Helicobacter pylori, and Chlamydia trachomatis .
|
-
- HY-N0465R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Olaquindox (Standard) is the analytical standard of Olaquindox. This product is intended for research and analytical applications. Olaquindox, a quinoxalin derivative, is an orally active antibiotic. Olaquindox stimulates growth and decreases intestinal mucosal immunity of piglets .
|
-
- HY-19791
-
-
- HY-116060
-
|
|
Antibiotic
PKC
Bacterial
Fungal
|
Infection
|
|
RK-286D is an antibiotic and a PKC inhibitor with antimicrobial activity. RK-286D shows inhibitory activities against bleb formation induced by PDBu (HY-18985) and in vitro PKC activity .
|
-
- HY-P4848
-
|
|
Antibiotic
|
Infection
|
|
Dermcidin-1L (human) is an antibiotic peptide secreted by sweat glands. Dermcidin-1L (human) has antimicrobial activity. Dermcidin-1L (human) can be used for the research of inflammatory skin disorders .
|
-
- HY-B0136
-
|
FK-482; CI-983
|
Bacterial
Antibiotic
|
Infection
|
|
Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .
|
-
- HY-B0467BR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Amoxicillin (trihydrate) (Standard) is the analytical standard of Amoxicillin (trihydrate). This product is intended for research and analytical applications. Amoxicillin (Amoxycillin) trihydrateis an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin trihydrateis inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
|
-
- HY-13434
-
|
SQ23377
|
Calcium Channel
PKC
Bacterial
Apoptosis
Antibiotic
|
Infection
Cancer
|
|
Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC) .
|
-
- HY-B0518A
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition .
|
-
- HY-155047
-
|
|
Bacterial
|
Infection
|
|
BDM91514 improves antibiotic potency through AcrB inhibition. BDM91514 prevents the growth of E. coliBW25113 (EC90: 8 μM) in the presence of 8 μg/mL Pyridomycin. BDM91514 has suitable plasma and microsomal stability .
|
-
- HY-N6686
-
|
Pristinamycin IIA; Ostreogrycin A
|
Bacterial
Antibiotic
|
Infection
|
|
Virginiamycin M1 (Pristinamycin IIA; Ostreogrycin A), produced by Streptomyces virginiae, is an polyunsaturated macrocyclic lactone antibiotic and acts as a component of Virginiamycin (HY-112665) . Virginiamycin M1 alone is against Staphylococcus aureus with a MIC of 0.25 μg/mL.
|
-
- HY-B1526
-
|
Thioacetazone; Amithiozone
|
Bacterial
Antibiotic
|
Infection
|
|
Thiacetazone (Thioacetazone) is a thiourea-containing antitubercular agent and is an orally active antibiotic. Thiacetazone has antibacterial action, which inhibits growth of Mycobacterium tuberculosis H37Rv with a MIC value of 0.1 μg/mL .
|
-
- HY-125117
-
|
|
DNA/RNA Synthesis
Bacterial
|
Infection
Cancer
|
|
Simocyclinone D8 is an anthracycline antibiotic with antibacterial and antitumor activity against Gram-positive bacteria. Simocyclinone D8 inhibits DNA gyrase and thus has an inhibitory effect on a variety of tumor cell lines .
|
-
- HY-129292
-
|
Quinocarmycin; DC-52; KW2152 free base
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Quinocarcin (DC-52) is a potent antitumor antibiotic. Quinocarcin inhibits Bacillus subtilis DNA, RNA and protein syntheses .
|
-
- HY-P10027
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Clovibactin is an antibiotic for drug-resistant bacterial pathogens without detectable resistance. Clovibactin TFA inihibits cell wall synthesis by targeting pyrophosphate of peptidoglycan precursors .
|
-
- HY-156198
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Bottromycin A2 is a natural antibiotic. Bottromycin A2 is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) .
|
-
- HY-156283
-
|
|
Antibiotic
|
Infection
|
|
Antibacterial agent 159 (Compound 6d) is an antibiotic. Antibacterial agent 159 can effective against impetigo and C. difficile infection (CDI). Antibacterial agent 159 has no observed recurrence for C. difficile and exertes a minimal impact on the beneficial gut microbiome .
|
-
- HY-115249R
-
|
|
Parasite
Antibiotic
Bacterial
|
Infection
|
|
Metronidazole acetic acid (Standard) is the analytical standard of Metronidazole acetic acid. This product is intended for research and analytical applications. Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa .
|
-
- HY-138023
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Leucomycin A4 is a macrolide antibiotic that can be extracted from S. kitasatoensis. Leucomycin A4 inhibits a variety of bacteria, including S. aureus, B. subtilis, C. diphtheriae, N. gonorrhoeae, and H. influenzae (MICs = 0.15, 1.25, 0.15, 0.6, and 0.15 µg/ml, respectively) .
|
-
- HY-105237
-
|
|
Antibiotic
DNA/RNA Synthesis
|
Cancer
|
|
Esperamicin A1, as an extremely potent antitumor antibiotic, is isolated from cultures of Actinomadura verrucosospora. Esperamicin A1 can be used for the research of antitumor . Eesperamicin A1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-P4200
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Lugdunin is an antibiotic peptide. Lugdunin inhibits bacteria by dissipating their membrane potential. Lugdunin is active against Gram-positive bacteria, such as S. aureus, and reduces S. aureus skin and nasal colonization. Lugdunin induces LL-37 and CXCL8/MIP-2 in human keratinocytes and mouse skin .
|
-
- HY-13234
-
|
|
Bacterial
Antibiotic
DNA/RNA Synthesis
|
Infection
Cancer
|
|
Rifaximin, a gastrointestinal-selective antibiotic, binds the β-subunit of bacterial DNA-dependent RNA polymerase, resulting in inhibition of bacterial RNA synthesis. Rifaximin susceptibility is higher against Gram-positive strains (MIC: 0.03-5 mg/ml) compared to Gram-negative bacteria (MIC: 8-50 mg/mL) .
|
-
- HY-B1267R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfaguanidine (Standard) is the analytical standard of Sulfaguanidine. This product is intended for research and analytical applications. Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery .
|
-
- HY-18061
-
|
(Rac)-STA-21
|
STAT
Bacterial
|
Infection
Cancer
|
|
Ochromycinone ((Rac)-STA-21) is a natural antibiotic and a STAT3 inhibitor. Ochromycinone can inhibits STAT3 DNA binding activity, STAT3 dimerization. Ochromycinone has anticancer and antimicrobial activity .
|
-
- HY-N13150A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
N-Demethylvancomycin hydrochloride is a glycopeptide antibiotic which can be found in Nocardia orientalis and active against several strains of S. aureus and S. epidermidis. N-Demethylvancomycin hydrochloride can be used for infection research .
|
-
- HY-103250
-
|
|
Antibiotic
|
Infection
|
|
PF-945863 is an orally active macrolide antibiotic that can be used for the research of multidrug resistant respiratory tract bacterial strains .
|
-
- HY-W015851
-
|
(R)-(-)-3-Hydroxybutanoic acid sodium; (R)-3-Hydroxybutyric acid sodium
|
Endogenous Metabolite
|
Metabolic Disease
|
|
(R)-3-Hydroxybutanoic acid ((R)-3-Hydroxybutyric acid) sodium is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones .
|
-
- HY-B1369A
-
|
N-Formimidoyl thienamycin; MK0787
|
Antibiotic
Bacterial
|
Infection
|
|
Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
|
-
- HY-125335
-
|
Rutamycin A
|
Ras
|
Cancer
|
|
Oligomycin D (Rutamycin A) is an antibiotic. Oligomycin D can be derived from a strain of S. rutgersensis. Oligomycin D also is a potent inhibitors of K-Ras PM localization. Oligomycin D can be used for the research of various cancers .
|
-
- HY-N13150
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
N-Demethylvancomycin is a glycopeptide antibiotic which can be extracted from Nocardia orientalis and active against several strains of S. aureus and S. epidermidis. N-Demethylvancomycin can be used for infection research .
|
-
- HY-B0322S1
-
|
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
|
Infection
|
|
Sulfamethoxazole- 13C6 is a 13C labeled Sulfamethoxazole. Sulfamethoxazole (Ro 4-2130) is a sulfonamide bacteriostatic antibiotic, used for bacterial infections. Sulfonamides is a competitive antagonist of para-aminobenzoic acid (PABA) .
|
-
- HY-B1329R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Apramycin (sulfate) (Standard) is the analytical standard of Apramycin (sulfate). This product is intended for research and analytical applications. Apramycin (EBL 1003) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic .
|
-
- HY-A0294
-
|
MK-0826
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Ertapenem (MK-0826) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .
|
-
- HY-13625
-
|
L-749345; MK-826
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Ertapenem sodium (L-749345) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem sodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem sodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .
|
-
- HY-17591R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Penicillin G (potassium) (Standard) is the analytical standard of Penicillin G (potassium). This product is intended for research and analytical applications. Penicillin G potassium is a fast-acting penicillin family antibiotic. Penicillin G potassium can be used for the research of bacterial infections that affect the blood, heart, lungs, joints, and genital areas .
|
-
- HY-106922
-
|
GV104326
|
Antibiotic
Bacterial
|
Infection
|
|
Sanfetrinem (GV104326) is a β-lactamase-stable antibiotic. Sanfetrinem has broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria .
|
-
- HY-B1252
-
-
- HY-N12654
-
|
|
Fungal
Parasite
Antibiotic
|
Infection
|
|
Irumamycin is a natural 20-membered macrolide antibiotic. Irumamycin is active in vitro against some phytopathogenic fungi . Irumamycin also shows potent antitrypanosomal activity .
|
-
- HY-B1252A
-
-
- HY-144767
-
|
|
Bacterial
|
Infection
|
|
PA3552-IN-1 (compound 15) is an antibiotic adjuvant that restores sensitivity of MDR P. aeruginosa DK2 strain to Polymyxin B. PA3552-IN-1 can reduce PA3552 expression .
|
-
- HY-B0212
-
|
|
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Sulfapyridine, a major metabolite of Sulfasalazine, is a sulfonamide antibiotic agent. Sulfapyridine inhibits recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. Sulfapyridine has antibacterial, anti-inflammatory and anti-rheumatic activities .
|
-
- HY-125104
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Mirosamicin is an antibiotic with high antibacterial activity that targets a wide range of gram-positive bacteria and certain Gram-negative bacteria as well as mycoplasma. Mirosamicin can be used for research in the field of food safety monitoring .
|
-
- HY-B0322A
-
|
Ro 4-2130 sodium
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic . Sulfamethoxazole sodium is used to treat various urinary tract pathogens and in combination with Trimethoprim is considered the gold standard in the treatment of urinary tract infections (UTIs) .
|
-
- HY-122494
-
|
SF-1293
|
Bacterial
|
Infection
|
|
Bilanafos is a natural organic phosphine tripeptide antibiotic metabolized by Streptomyces hydroscopius or Streptomyces viridochromeogenes. Bialaphos has antimicrobial activity aganist Gram-negative and positive bacteria as well as some fungal plant diseases .
|
-
- HY-102026
-
-
- HY-135751
-
|
|
Antibiotic
DNA/RNA Synthesis
|
Infection
Cancer
|
|
Holomycin is a secondary metabolite of the dithiolopyrrolone class. Holomycin also is a broad spectrum antibiotic. Holomycin has antitumor activity and can act in vivo on RNA synthesis .
|
-
- HY-13434A
-
|
SQ23377 calcium
|
Calcium Channel
PKC
Bacterial
Apoptosis
Antibiotic
|
Infection
Cancer
|
|
Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin calcium (SQ23377 calcium) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin calcium (SQ23377 calcium) also induces the activation of protein kinase C (PKC) .
|
-
- HY-136457R
-
|
|
Drug Metabolite
|
Others
|
|
2-NP-AHD (Standard) is the analytical standard of 2-NP-AHD. This product is intended for research and analytical applications. 2-NP-AHD is a 2-nitrophenyl derivative of AHD (a metabolite of nitrofurans type of antibiotics), can be used as indicator of the illegal usage of nitrofuran agents .
|
-
- HY-129252
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Prothracarcin is an antibiotic with antitumor activity that exerts its tumor cell toxicity by covalently binding to the C-2 amino group of guanine residues in the minor groove of DNA. Prothracarcin also shows antibacterial activity against Gram-positive bacteria and some Gram-negative bacteria such as Escherichia coli .
|
-
- HY-108345
-
|
|
Antibiotic
|
Cancer
|
|
Bleomycin is a glycopeptide antibiotic. Bleomycin has potent antitumour activities against a range of lymphomas, head and neck cancers and germ-cell tumours. Bleomycin can be used for the research of cancer and chemotherapy .
|
-
- HY-N15029
-
|
|
Antibiotic
Bacterial
Fungal
Parasite
Adenylate Cyclase
|
Infection
|
|
Destomycin A is an aminoglycoside antibiotic with antibacterial (Gram-positive bacteria, Gram-negative bacteria), antifungal and anthelmintic activities. Destomycin A inhibits the polypeptide synthesis in cells of Escherichia coli and stimulation of adenylate cyclase in animal tissues .
|
-
- HY-77641R
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Cinnamoylglycine (Standard) is the analytical standard of Cinnamoylglycine. This product is intended for research and analytical applications. Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment .
|
-
- HY-N10273
-
|
|
Fungal
|
Infection
|
|
Deoxyfusapyrone is an antifungal alpha-pyrone from Fusarium semitectum. Deoxyfusapyrone shows a strong antibiotic activity towards Geotrichum candidum in disk diffusion assays, but is not toxic to Artemia salina larvae .
|
-
- HY-B1327R
-
|
|
Bacterial
Antibiotic
Parasite
|
Infection
Inflammation/Immunology
|
|
Chlortetracycline (hydrochloride) (Standard) is the analytical standard of Chlortetracycline (hydrochloride). This product is intended for research and analytical applications. Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is a specific and potent calcium ionophore antibiotic that inhibits the binding of aminoacyl-tRNA to ribosomes.
|
-
- HY-N12201
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Funiculosin is a neutral lipophilic antibiotic that inhibits DNA and RNA viruses. Funiculosin also has antifungal activity. Funiculosin inhibits infections caused by pathogenic fungi in primary chicken embryo fibroblasts .
|
-
- HY-A0251R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cefpodoxime (Standard) is the analytical standard of Cefpodoxime. This product is intended for research and analytical applications. Cefpodoxime (Cefpodoxime acid) is a potent antibiotic active against gram-positive and gram-negative bacteria. Cefpodoxime inhibits the majority of cells in microbial populations. Cefpodoxime can be used for acute otitis media, sinusitis and tosillopharyngitis research .
|
-
- HY-128423R
-
|
|
Antibiotic
Bacterial
NF-κB
Apoptosis
|
Infection
Inflammation/Immunology
|
|
Tylvalosin (tartrate) (Standard) is the analytical standard of Tylvalosin (tartrate). This product is intended for research and analytical applications. Tylvalosin (Acetylisovaleryltylosin) tartrate is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin tartrate is an antiviral agent useful in studying PRRSV infection. Tylvalosin tartrate induces apoptosis. Tylvalosin tartrate also has anti-inflammatory activity, relieves oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation [4].
|
-
- HY-B0136R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefdinir (Standard) is the analytical standard of Cefdinir. This product is intended for research and analytical applications. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .
|
-
- HY-A0294A
-
|
MK-0826 disodium
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Ertapenem (MK-0826) disodium is a broad spectrum and long acting β-lactam antibiotic. Ertapenem disodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem disodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .
|
-
- HY-108402
-
|
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
|
|
Cefodizime is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime has no renal toxic effect, good tolerance and immune regulation activity, and has the potential for severe infections of the respiratory and urinary tracts .
|
-
- HY-136457S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2-NP-AHD- 13C3 is the 13C labled 2-NP-AHD (HY-136457) . 2-NP-AHD is a 2-nitrophenyl derivative of AHD (a metabolite of nitrofurans type of antibiotics), can be used as indicator of the illegal usage of nitrofuran agents .
|
-
- HY-125652
-
|
|
Antibiotic
|
Infection
|
|
Macrosphelide A is a macrolide antibiotic. Macrosphelide A inhibits growth of some ascomycetes, basidiomycetes, oomycetes and all four Gram-positive bacteria tested, including the medically important Staphylococcus aureus with a MIC of ≤500 μg/mL .
|
-
- HY-108402A
-
|
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
|
|
Cefodizime sodium is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime sodium has no renal toxic effect, good tolerance and immune regulation activity, and can be used for the research of severe infections of the respiratory and urinary tracts .
|
-
- HY-162861
-
|
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
3-Methyl-chuangxinmycin is an antibiotic. 3-Methyl-chuangxinmycin can affect the translation process in bacteria and mammalian cells by inhibiting the enzyme that synthesizes tryptophan tRNA (TrpRS). 3-Methyl-chuangxinmycin can downregulate genes related to interferon, TNF, and inflammatory responses in RDEB_L1 cells .
|
-
- HY-A0248
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Polymyxin B Sulfate is a potent antibacterial agent and a relatively toxic antibiotic. Polymyxin B Sulfate also is a antiendotoxin agent. Polymyxin B Sulfate shows endotoxin-neutralizing properties can be used as adjunctive research in gram-negative sepsis. Polymyxin B Sulfate shows antibacterial activities in vitro and in vivo .
|
-
- HY-16035A
-
|
|
DNA/RNA Synthesis
Antibiotic
|
Infection
|
|
Alatrofloxacin mesylate is an antibiotic with antibacterial activity. Alatrofloxacin mesylate exhibits significant hydrophilicity in the aqueous phase, forming a very stable suspension. The degradation products of Alatrofloxacin mesylate become hydrophobic upon exposure, causing aggregation of its particles. The long-term stability of Alatrofloxacin mesylate is closely related to its polar interaction. The changes in surface tension characteristics of Alatrofloxacin mesylate particles under different lighting conditions affect their physical and chemical properties .
|
-
- HY-B0278R
-
|
Zinc bacitracin (Standard)
|
Bacterial
Antibiotic
|
Infection
|
|
Bacitracin Zinc (Standard) is the analytical standard of Bacitracin Zinc (HY-B0278). Bacitracin Zinc (Standard) is a complex formed by the binding of Bacitracin (HY-107193) with zinc ions. Bacitracin Zinc (Standard) is an orally active polypeptide antibiotic with bactericidal properties. Bacitracin Zinc (Standard) can cause DNA and deoxyribose damage, as well as improve the gut microbiota of broiler and beef cattle .
|
-
- HY-105463
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Saptomycin D is an antibiotic with antitumor activity isolated from the Streptomyces sp. HP530 strain. Saptomycin D exhibits potent inhibitory effects against Gram-positive bacteria, while demonstrating weaker inhibitory activities against certain Gram-negative bacteria and yeasts. Saptomycin D also displays remarkable antitumor properties. Saptomycin D is applicable in research within the field of oncology .
|
-
- HY-P2233
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Globomycin is a lipopeptide antibiotic and a signal peptidase II (LspA) inhibitor. Globomycin inhibits processing of the prolipoprotein by binding irreversibly to the peptidase. Globomycin has toxic for the mollicute Spiroplasma melliferum with a MIC in the range 6.25-12.5 μM .
|
-
- HY-16137
-
|
Cephaloglycin
|
Bacterial
|
Infection
|
|
Cefaloglycin (Cephaloglycin) is an orally active nephrotoxic β-lactam cephalosporin antibiotic with antibacterial activity. Cefaloglycin is activity against Gram-Positive cocci other than enterococci. Cefaloglycin is toxic to mitochondrial substrate uptake and respiration .
|
-
- HY-N7449
-
-
- HY-13234R
-
|
|
Bacterial
Antibiotic
DNA/RNA Synthesis
|
Infection
Cancer
|
|
Rifaximin (Standard) is the analytical standard of Rifaximin. This product is intended for research and analytical applications. Rifaximin, a gastrointestinal-selective antibiotic, binds the β-subunit of bacterial DNA-dependent RNA polymerase, resulting in inhibition of bacterial RNA synthesis. Rifaximin susceptibility is higher against Gram-positive strains (MIC: 0.03-5 mg/ml) compared to Gram-negative bacteria (MIC: 8-50 mg/mL) .
|
-
- HY-155504
-
|
|
Beta-lactamase
Bacterial
|
Infection
|
|
Metallo-β-lactamase-IN-11 (compound 5f) is a Metallo-β-lactamases (MBLs) inhibitor, potent against bacterial metallophyllactamase CphA (IC50=45 µM). Metallo-β-lactamase-IN-11 (10 µM) inhibits NDM-1 by 49% and AIM-1 by 61%. Metallo-β-lactamase-IN-11 can be used in the research of inhibiting antibiotic resistance .
|
-
- HY-138075
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Obafluorin is a β-Lactone Antibiotic, that can be produced by Pseudomonas fluorescens ATCC 39502. Obafluorin exhibits antibacterial activity against a range of Gram-positive and Gram-negative bacteria. Obafluorin fully inhibits E. coli threonyl-tRNA synthetase .
|
-
- HY-B1703
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Nifursol is a potent and orally active veterinary antibiotic for the prevention of histomoniasis. Nifursol rapidly metabolizes to form the metabolic marker 3,5-dinitrosalicyclic acid hydrazide (DNSAH) which can persist for a long time. Nifursol is widely used for the research of Escherichia Gastroenteropathy in poultry, fowl and aquatic animal .
|
-
- HY-109539
-
|
|
Antibody-Drug Conjugates (ADCs)
Apoptosis
|
Cancer
|
|
Gemtuzumab ozogamicin is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin (IgG4) antibody directed against CD33 that is conjugated to the cytotoxic agent Calicheamicin (HY-19609). Calicheamicin is a cytotoxic antibiotic. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia (AML) .
|
-
- HY-B0518AR
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Naftifine (hydrochloride) (Standard) is the analytical standard of Naftifine (hydrochloride). This product is intended for research and analytical applications. Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition .
|
-
- HY-17586
-
|
MDL-63397 hydrochloride; BI-397 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Dalbavancin hydrochloride (MDL-63397 hydrochloride) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin hydrochloride inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively .
|
-
- HY-17586A
-
|
MDL-63397; BI-397
|
Bacterial
Antibiotic
|
Infection
|
|
Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively .
|
-
- HY-N4117
-
|
|
Bacterial
|
Infection
|
|
Hamamelitannin, a polyphenol extracted from the bark of Hamamelis virginiana, is a quorum-sensing (QS) inhibitor. Hamamelitannin increases antibiotic susceptibility of staphylococcus aureus biofilms by affecting peptidoglycan biosynthesis and eDNA release .
|
-
- HY-19071
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
BK-218 is an orally active cephalosporin antibiotic that binds to penicillin-binding proteins (PBPs) and has a greater inhibitory effect than Cephalexin (HY-B0200) and Cefoxitin (HY-B1825). BK-218 has similar antibacterial activity to Cefamandole (HY-B1128) and can be used in the development of antibacterial drugs .
|
-
- HY-B1369AR
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Imipenem (Standard) is the analytical standard of Imipenem. This product is intended for research and analytical applications. Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
|
-
- HY-N5160
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Arborcandin A is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin A exhibits IC50 values of 0.25 μg/mL and 0.05 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin A has an MIC of 4-8 μg/mL against the genus Candida .
|
-
- HY-N5165
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Arborcandin F is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin F exhibits IC50 values of 0.012 μg/mL against both Candida albicans and Aspergillus fumigatus. Additionally, Arborcandin F has an MIC of 2-4 μg/mL against the genus Candida .
|
-
- HY-W013549R
-
|
|
Drug Metabolite
Bacterial
|
Infection
|
|
6-Aminopenicillanic acid (Standard) is the analytical standard of 6-Aminopenicillanic acid. This product is intended for research and analytical applications. 6-Aminopenicillanic acid (6-APA) is an important precursor for the synthesis of ?-lactam antibiotics. 6-Aminopenicillanic acid is the main product of Penicillin G (PenG) hydrolyzed by penicillin acylase (PA) .
|
-
- HY-B0479
-
|
Thiophenicol; Dextrosulphenidol
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
|
-
- HY-163331
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cresomycin is a bridged macrobicyclic antibiotic that can bind to the bacterial ribosome. Cresomycin exhibits efficacy against both Gram-positive and Gram-negative bacteria, including multidrug-resistant strains of Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa .
|
-
- HY-A0090A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Nitrofurantoin sodium is a potent and orally active antibacterial agent. Nitrofurantoin sodium acts as an antibiotic. Nitrofurantoin sodium can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .
|
-
- HY-136943
-
|
|
Antibiotic
Parasite
Bacterial
|
Infection
|
|
K-41 is an orally active antibiotic. K-41 can be obtained from Streptomyces hygroscopicus. K-41 has antibacterial and antiplasmodial activity .
|
-
- HY-115349
-
|
|
Antibiotic
Bacterial
|
Infection
Neurological Disease
Cancer
|
|
Neamine tetrahydrochloride, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine tetrahydrochloride is an anti-angiogenesis agent targeting angiogenin. Neamine tetrahydrochloride has potent antibacterial, antitumor and neuroprotective activities .
|
-
- HY-N5163
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Arborcandin D is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin D exhibits IC50 values of 3 μg/mL and 0.35 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin D has an MIC of 4 μg/mL against the genus Candida .
|
-
- HY-N6686R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Virginiamycin M1 (Standard) is the analytical standard of Virginiamycin M1. This product is intended for research and analytical applications. Virginiamycin M1 (Pristinamycin IIA; Ostreogrycin A), produced by Streptomyces virginiae, is an polyunsaturated macrocyclic lactone antibiotic and acts as a component of Virginiamycin (HY-112665) . Virginiamycin M1 alone is against Staphylococcus aureus with a MIC of 0.25 μg/mL.
|
-
- HY-B0356B
-
|
Bay-09867 hydrochloride monohydrate
|
Topoisomerase
Apoptosis
Antibiotic
Bacterial
Mitochondrial Metabolism
Reactive Oxygen Species
|
Infection
Cancer
|
|
Ciprofloxacin (Bay-09867) hydrochloride monohydrate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin hydrochloride monohydrate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin hydrochloride monohydrate has anti-proliferative activity and induces apoptosis. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .
|
-
- HY-121071
-
|
|
Bacterial
Nucleoside Antimetabolite/Analog
Antibiotic
|
Infection
|
|
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. Ascamycin has a selective antibacterial activity against Xanthomonas species with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL for Xanthomonas citri, Xanthomonas oryzae and Mycobacterium phlei, respectively .
|
-
- HY-N5162
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Arborcandin C is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin C exhibits IC50 values of 0.15 μg/mL and 0.015 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin C has an MIC of 1-2 μg/mL against the genus Candida .
|
-
- HY-B0395B
-
|
DU6859a monohydrate
|
Bacterial
Antibiotic
|
Infection
|
|
Sitafloxacin (DU6859a) monohydrate is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin monohydrate shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin monohydrate can be used for the research of respiratory tract infection and urinary tract infection .
|
-
- HY-N5161
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Arborcandin B is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin B exhibits IC50 values of 0.30 μg/mL and 0.025 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin B has an MIC of 2-4 μg/mL against the genus Candida .
|
-
- HY-B0356
-
-
- HY-B0975
-
|
Phenoxymethylpenicillin potassium salt
|
Bacterial
Antibiotic
|
Infection
|
|
Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally active antibiotic. Penicillin V Potassium inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V Potassium can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis .
|
-
- HY-B1252R
-
|
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
|
Cefalonium (Standard) is the analytical standard of Cefalonium. This product is intended for research and analytical applications. Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .
|
-
- HY-121544A
-
|
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
Histamine Receptor
|
Infection
|
|
Methicillin sodium hydrate is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin sodium hydrate is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins. Methicillin sodium hydrate can be used for the research of skin infections, osteomyelitis, and endocarditis .
|
-
- HY-130838
-
|
|
Bacterial
|
Infection
|
|
JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-33 displays outstanding antibiotic activity with a MIC value of 0.66 μg/mL .
|
-
- HY-130837
-
|
|
Bacterial
|
Infection
|
|
JH-LPH-28, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-28 displays outstanding antibiotic activity with a MIC value of 0.83 μg/mL .
|
-
- HY-121544
-
|
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
Histamine Receptor
|
Infection
|
|
Methicillin is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins.Methicillin can be used for the research of skin infections, osteomyelitis, and endocarditis .
|
-
- HY-N5164
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Arborcandin E is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin E exhibits IC50 values of 0.1 μg/mL and 0.012 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin E has an MIC of 0.5-2 μg/mL against the genus Candida .
|
-
- HY-136288
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Azide-PEG4-VC-PAB-Doxorubicin is a agent-linker conjugate composed of a cytotoxic anthracycline antibiotic Doxorubicin and a linker Azide-PEG4-VC-PAB to make antibody agent conjugate (ADC) . Azide-PEG4-VC-PAB-Doxorubicin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-77036
-
Furagin
1 Publications Verification
Furazidine; Furazidin
|
Antibiotic
Bacterial
Carbonic Anhydrase
|
Infection
Cancer
|
|
Furagin (Furazidine), an analogue of Nitrofurantoin (HY-A0090), is an antibiotic with antibacterial activity against ESKAPE pathogens with MIC values of 0-32 µg/mL. Furagin inhibits human Carbonic anhydrases . Furagin is promising for research of cancer and urinary tract infections (UTIs) .
|
-
- HY-B0228S10
-
|
(R)-(-)-3-Hydroxybutanoic acid-13C2 sodium; (R)-3-Hydroxybutyric acid-13C2 sodium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
(R)-3-Hydroxybutanoic acid- 13C2 (sodium) is the 13C labeled (R)-3-Hydroxybutanoic acid (sodium) (HY-W015851). (R)-3-Hydroxybutanoic acid (sodium) is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones[1][2][3].
|
-
- HY-A0090
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .
|
-
- HY-19829
-
|
|
ADC Cytotoxin
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor activity .
|
-
- HY-108402R
-
|
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
|
|
Cefodizime (Standard) is the analytical standard of Cefodizime. This product is intended for research and analytical applications. Cefodizime is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime has no renal toxic effect, good tolerance and immune regulation activity, and has the potential for severe infections of the respiratory and urinary tracts .
|
-
- HY-108486
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Herbimycin A, an ansamycin antibiotic, acts as a Src family kinase inhibitor. Herbimycin A binds to the SH domain and inhibits the activity of p60 v-src and p210 BCR-ABL Herbimycin A inhibits Hsp90 and impairs recovery from heat shock. Herbimycin A exhibits antiangiogenic activity in endothelial cells in vitro.
|
-
- HY-N0565
-
|
|
MMP
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
|
Doxycycline, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline shows antibacterial activity and anti-cancer cell proliferation activity .
|
-
- HY-N0565A
-
|
|
MMP
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
|
Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hydrochloride shows antibacterial activity and anti-cancer cell proliferation activity .
|
-
- HY-159687
-
|
WCK 4873
|
Antibiotic
Bacterial
|
Infection
|
|
Nafithromycin (WCK 4873) is an orally available antibiotic that inhibits community-acquired pneumonia caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Methicillin (HY-121544)-susceptible Staphylococcus aureus. The MIC90 of nafithromycin against macrolide-resistant and telithromycin (HY-A0062)-insensitive Streptococcus pneumoniae is 0.12 mg/liter .
|
-
- HY-W040298
-
|
Bay-09867 lactate
|
Topoisomerase
Apoptosis
Antibiotic
Bacterial
Mitochondrial Metabolism
Reactive Oxygen Species
|
Infection
Cancer
|
|
Ciprofloxacin (Bay-09867) lactate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin lactate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin lactate has anti-proliferative activity and induces apoptosis. Ciprofloxacin lactate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .
|
-
- HY-D1571
-
|
|
DNA Stain
|
Others
|
|
CellTracker Blue CMF2HC Dye is a blue dye, can be used in two-channel nuclei acid sequencing, with blue and purple excitation light (450-460 nm/400-405nm or 415-450 nm/480-525nm). CellTracker Blue CMF2HC Dye can be used to rapid determination of antibiotic sensitivity of microorganisms .
|
-
- HY-B0356A
-
|
Bay-09867 monohydrochloride
|
Topoisomerase
Apoptosis
Antibiotic
Bacterial
Mitochondrial Metabolism
Reactive Oxygen Species
|
Infection
Cancer
|
|
Ciprofloxacin (Bay-09867) monohydrochloride is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin monohydrochloride induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin monohydrochloride has anti-proliferative activity and induces apoptosis. Ciprofloxacin monohydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .
|
-
- HY-118906
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
BO-1165 is an antibiotic with good antibacterial activity against Gram-negative bacteria, but almost no activity against Gram-positive bacteria and anaerobic bacteria. BO-1165 has high antibacterial activity against Pseudomonas aeruginosa (MIC50=3.12 mg/L) and P. cepacia (MIC50=1.56 mg/L) .
|
-
- HY-129217
-
|
|
Glycosidase
|
Others
|
|
Naringinase, a hydrolytic enzymatic complex, possesses the activity of both α-L-rhamnosidase and β-D-glucosidase. Naringinase has wide occurrence in nature. Naringinase can be used in the biotransformation of steroids, antibiotics, and mainly on glycosides hydrolysis .
|
-
- HY-B0975A
-
|
Phenoxymethylpenicillin
|
Antibiotic
Bacterial
|
Infection
|
|
Penicillin V (Phenoxymethylpenicillin) is a potent and orally active antibiotic. Penicillin V shows antibacterial activity for Streptococci, Clostridium difficile and staphylococcus aureus. Penicillin V has the potential for the research of otitis, sinusitis, pharyngitis and tonsillitis .
|
-
- HY-120435
-
|
|
Bacterial
Fungal
Influenza Virus
Antibiotic
|
Infection
|
|
Tyrothricin is a polypeptide antibiotic mixture isolated from Bacillus brevis and consists of tyrocidines and gramicidins. Tyrothricin shows activity against bacteria, fungi and some viruses. Tyrothricin containing formulations are used in sore throat agents and in agents for the healing of infected superficial and small-area wounds .
|
-
- HY-B1252AS
-
|
|
Isotope-Labeled Compounds
|
Infection
|
|
Cefalonium-d4 (hydrate) is the deuterium labeled Cefalonium (hydrate)(HY-B1252A).Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .
|
-
- HY-106338
-
|
|
Bacterial
ADC Cytotoxin
Parasite
|
Infection
Cancer
|
|
Polyketomycin is a tetracyclic quinone glycoside antibiotic isolated from Streptomyces sp. or Streptomyces diastatochromogenes. Polyketomycin inhibits growth of Gram-positive bacteria, and its MIC values is less than 0.2 µg/mL. Polyketomycin has antibacterial, anticancer, antimalarial activities .
|
-
- HY-121348
-
|
U-47929
|
Antibiotic
Bacterial
DNA/RNA Synthesis
|
Infection
|
Ficellomycin is a nitrogen-containing bicyclic antibiotic with strong activity against Gram-positive bacteria, including multidrug-resistant strains of Staphylococcus aureus. Ficellomycin works by inducing the formation of defective 34S DNA fragments, which interfere with the semi-conservative DNA replication process. These fragments lack the ability to integrate into larger DNA segments and eventually form a complete bacterial chromosome. Ficellomycin can be used in research for various bacterial diseases .
|
-
- HY-149810
-
|
|
Bacterial
Parasite
|
Infection
|
|
AcrB-IN-2 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. AcrB-IN-22 inhibits Nile Red (a known substrate of AcrB) efflux.AcrB-IN-2 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model .
|
-
- HY-110013
-
|
|
Btk
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Terreic acid, a quinone epoxide antibiotic, acts as an effective Btk inhibitor. Terreic acid blocks the interaction between PKC and the pleckstrin homology domain of Btk. Terreic acid inhibits the binding of GST-BtkPH to PKC in lysates of HMC-1 human mast cells with an IC50 of approximately 100 μM .
|
-
- HY-B1002
-
|
|
Bacterial
Antibiotic
DNA/RNA Synthesis
|
Infection
|
|
Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice .
|
-
- HY-119819
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Psicofuramine a nucleoside antibiotic and has the inhibition of xanthosine 5'-phosphate aminase. Psicofuranine also specifically inhibits GMP synthase, and interrupts parasite growth. Psicofuranine exhibits a dose-dependent inhibition of P. falciparum growth .
|
-
- HY-B0479S
-
|
Thiophenicol-d3; Dextrosulphenidol-d3
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Thiamphenicol-d3 is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria)[1][2].
|
-
- HY-122534
-
|
|
Mitochondrial Metabolism
ADC Cytotoxin
Apoptosis
|
Cancer
|
|
Mensacarcin, a highly complex polyketide, strongly inhibits cell growth universally in cancer cell lines and potently induces apoptosis in melanoma cells. Mensacarcin targets to mitochondria, affects energy metabolism in mitochondria, and activates caspase-dependent apoptotic pathways. Mensacarcin, an antibiotic, can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
|
-
- HY-B0395A
-
|
DU6859a hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Sitafloxacin (DU6859a) hydrochloride is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin hydrochloride shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin hydrochloride can be used for the research of respiratory tract infection and urinary tract infection .
|
-
- HY-B0856
-
|
|
Fungal
Tyrosinase
Antibiotic
|
Infection
|
|
Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1 μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC50 of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM .
|
-
- HY-B0536A
-
|
AM 1091 hydrochloride; CI 960 hydrochloride; PD127391 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Clinafloxacin hydrochloride (AM 1091 hydrochloride) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro . Clinafloxacin hydrochloride is against DNA gyrase and topoisomerase IV of S. aureus with IC50 values of 0.92 µg/ml and 1.62 µg/ml, respectively .
|
-
- HY-B0536
-
|
AM-1091; CI-960; PD 127391
|
Bacterial
Antibiotic
|
Infection
|
|
Clinafloxacin (AM 1091) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro . Clinafloxacin is against DNA gyrase and topoisomerase IV of?S. aureus with IC50 values of 0.92 μg/ml and 1.62 μg/ml, respectively .
|
-
- HY-P0311
-
|
|
Bacterial
|
Infection
|
|
LAH4, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 possesses high plasmid DNA delivery capacities. LAH4 has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .
|
-
- HY-B0395
-
|
DU6859a
|
Bacterial
Antibiotic
|
Infection
|
|
Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection .
|
-
- HY-N0565B
-
|
Doxycycline hydrochloride hemiethanolate hemihydrate; WC2031
|
Antibiotic
MMP
Bacterial
Parasite
|
Infection
Cancer
|
|
Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hyclate shows antibacterial activity and anti-cancer cell proliferation activity .
|
-
- HY-N0565C
-
|
|
MMP
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
|
Doxycycline calcium, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline calcium shows antibacterial activity and anti-cancer cell proliferation activity .
|
-
- HY-139554
-
|
KBP-7072
|
Bacterial
|
Infection
|
|
Zifanocycline (KBP-7072) is a semisynthetic third-generation aminomethylcycline antibiotic that inhibits the normal function of the bacterial ribosome. Zifanocycline exhibits a broad spectrum of in vitro antibacterial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline is available in both oral and injectable formulations. Zifanocycline can be used for the research of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections .
|
-
- HY-B1916
-
|
Spiramycin B; Spiramycin II; Foromacidin B
|
Antibiotic
Bacterial
Parasite
|
Infection
|
|
Acetylspiramycin (Spiramycin B) is an effective oral macrolide antibiotic produced by Streptomyces, It can inhibit the splenic lymphocyte transformation induced by phytohemagglutinin (PHA), LPS (HY-D1056) and antigen, reduce the procoagulant activity of macrophages, have good antibacterial effect on gram-positive bacteria, and is also an effective antigenic insect agent, which can be used to fight parasitic infection .
|
-
- HY-B0275
-
|
|
Bacterial
HSV
Endogenous Metabolite
Antibiotic
|
Infection
|
|
Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity .
|
-
- HY-B0275A
-
|
|
Bacterial
HSV
Antibiotic
Endogenous Metabolite
|
Infection
|
|
Oxytetracycline hydrochloride is an antibiotic belonging to the tetracycline class. Oxytetracycline hydrochloride potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity .
|
-
- HY-124508
-
-
- HY-P0311A
-
|
|
Bacterial
|
Infection
|
|
LAH4 TFA, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 TFA possesses high plasmid DNA delivery capacities. LAH4 TFA has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .
|
-
- HY-W399940
-
|
|
Antibiotic
Influenza Virus
Drug Intermediate
|
Infection
|
|
Actiphenol is an antibiotic against coxsackievirus B3 and influenza A virus (IC50s = 14.37 and 34.4 µg/mL, respectively). Actiphenol is also an aromatic ketone that exhibits weak eukaryotic translation inhibiton activity, which is found in Streptomyces species. Actiphenol can be used as a key intermediate to synthesize Cycloheximide (HY-12320) .
|
-
- HY-149812
-
|
|
Bacterial
Parasite
|
Infection
|
|
Efflux pump-IN-4 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-4 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-4 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model .
|
-
- HY-149811
-
|
|
Bacterial
Parasite
|
Infection
|
|
Efflux pump-IN-3 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-3 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-3 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model .
|
-
- HY-B0356R
-
|
|
Topoisomerase
Apoptosis
Antibiotic
Bacterial
Mitochondrial Metabolism
Reactive Oxygen Species
|
Infection
Cancer
|
|
Ciprofloxacin (Standard) is the analytical standard of Ciprofloxacin. This product is intended for research and analytical applications. Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and induces apoptosis. Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .
|
-
- HY-B0356BR
-
|
|
Topoisomerase
Apoptosis
Antibiotic
Bacterial
Mitochondrial Metabolism
Reactive Oxygen Species
|
Infection
Cancer
|
|
Ciprofloxacin (hydrochloride monohydrate) (Standard) is the analytical standard of Ciprofloxacin (hydrochloride monohydrate). This product is intended for research and analytical applications. Ciprofloxacin (Bay-09867) hydrochloride monohydrate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin hydrochloride monohydrate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin hydrochloride monohydrate has anti-proliferative activity and induces apoptosis. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .
|
-
- HY-N13221
-
|
|
Bacterial
Reactive Oxygen Species
Fungal
|
Cardiovascular Disease
Metabolic Disease
Cancer
|
Apple Cider Vinegar Powder is a soluble powdered form of apple cider vinegar. Apple Cider Vinegar Powder has anti-bacterial, anti-oxidant, and antibiotic properties and can help maintain the acid-base balance in the blood. Apple Cider Vinegar Powder can lower blood sugar and lipid levels. Apple Cider Vinegar Powder is used in research related to tumors, diabetes, and cardiovascular diseases .
|
-
- HY-N13197
-
-
- HY-B0027
-
|
|
Antibiotic
Bacterial
|
Infection
Metabolic Disease
|
|
Valnemulin hydrochloride is an orally effective truncated pleurotin antibiotic that inhibits protein synthesis in bacteria by binding to peptidyl transferase in the 50s ribosome subunit. Valnemulin hydrochloride effectively eliminates Mycobacterium bovis in the lungs in an experimental bovine model of Mycoplasma bovis infection. Valnemulin hydrochloride can reduce the mortality of epidemic rabbit enteropathy and has no adverse effect on the growth performance of rabbits .
|
-
- HY-106410A
-
|
DW-224a
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
|
Zabofloxacin hydrochloride (DW-224a) is a potent and seletive inhibitor of the bacterial type II and IV topoisomerases. Zabofloxacin hydrochloride has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia. Zabofloxacin hydrochloride is a novel fluoronaphthyridone quinolone that is considered as an alternative antibiotic for treatment of quinolone-susceptible (QSSP) and quinolone-resistant gonorrhea (QRSP) .
|
-
- HY-N6716
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Filipin complex is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I .
|
-
- HY-P3078
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Amphomycin is a lipopeptide antibiotic that inhibits peptidoglycan synthesis and blocks cell wall development. Amphomycin exhibits potent antibacterial activities against methicillin-resistant S. aureus (MRSA), vancomycin-resistant enterococci (VRE), penicillin-gentamicin-erythromycin-resistant S. pneumonia, and linezolid-quinupristin-dalfopristin-resistant enterococci .
|
-
- HY-W142073
-
|
7-Methyltryptophan
|
Amino Acid Derivatives
|
Infection
|
|
7-Methyl-DL-tryptophan (7-Methyltryptophan) is an amino acid derivative, which is a key precursor for biosynthesis of many non-ribosomal peptide antibiotics. 7-Methyl-DL-tryptophan plays an important role in synthesis of high-efficiency antibacterial agents and analogues thereof .
|
-
- HY-B0275C
-
|
|
Bacterial
HSV
Antibiotic
Endogenous Metabolite
|
Infection
|
|
Oxytetracycline calcium is an antibiotic belonging to the tetracycline class. Oxytetracycline calcium potently inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline calcium is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline calcium also possesses anti-HSV-1 activity .
|
-
- HY-B0275B
-
|
|
Bacterial
HSV
Antibiotic
Endogenous Metabolite
|
Infection
|
|
Oxytetracycline dihydrate is an antibiotic belonging to the tetracycline class. Oxytetracycline dihydrate potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline dihydrate is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline dihydrate also possesses anti-HSV-1 activity .
|
-
- HY-125365
-
|
|
Bacterial
Reactive Oxygen Species
Antibiotic
|
Infection
|
|
Rifamycin S, a quinone, is an antibiotic against Gram-positive bacteria (including MRSA). Rifamycin S is the oxidized forms of a reversible oxidation-reduction system involving two electrons. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. Rifamycin S can be used for tuberculosis and leprosy .
|
-
- HY-103397
-
|
|
Antibiotic
DNA Methyltransferase
Parasite
|
Infection
Cancer
|
|
Nanaomycin A is the first selective DNMT3B inhibitor with an IC50 of 500 nM. Nanaomycin A, a quinone antibiotics, reactivates silenced tumor suppressor genes in human cancer cells . Nanaomycin A inhibits in vitro growth of the human malaria parasite Plasmodium falciparum with an IC80 value of 33.1 nM .
|
-
- HY-106410
-
|
DW-224a Free base
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
|
Zabofloxacin (DW-224a Free base) is a potent and seletive inhibitor of the bacterial type II and IV topoisomerases. Zabofloxacin has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia. Zabofloxacin is a novel fluoronaphthyridone quinolone that is considered as an alternative antibiotic for treatment of quinolone-susceptible (QSSP) and quinolone-resistant gonorrhea (QRSP) .
|
-
- HY-121544AR
-
|
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
Histamine Receptor
|
Infection
|
|
Methicillin (sodium hydrate) (Standard) is the analytical standard of Methicillin (sodium hydrate). This product is intended for research and analytical applications. Methicillin sodium hydrate is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin sodium hydrate is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins. Methicillin sodium hydrate can be used for the research of skin infections, osteomyelitis, and endocarditis .
|
-
- HY-B0919
-
|
CI-337; O-Diazoacetyl-L-serine; P-165
|
Bacterial
Antibiotic
DNA/RNA Synthesis
|
Infection
Cancer
|
|
Azazerine (CI-337) is a competitive inhibitor of glutamine amidotransferase. Azaserine is an antibiotic, it shows antibacterial activities. Azazerine shows anti-tumor activities and it may also act as a tumor inducer. Azazerine can be used for the research of cancer and infection .
|
-
- HY-N6796
-
|
|
Antibiotic
Farnesyl Transferase
Ras
Apoptosis
Phospholipase
TNF Receptor
Atg8/LC3
|
Infection
Inflammation/Immunology
Cancer
|
|
Manumycin A is a polyketide antibiotic and an inhibitor of thioredoxin reductase 1 (TrxR-1). Manumycin A can inhibit the growth of breast cancer cells and exert its anti-tumor activity through LC3. Manumycin A can downregulate the release of pro-inflammatory cytokines in human monocytes stimulated by TNF α, and has potential anti-inflammatory activity. Manumycin A can inhibit the Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration resistant prostate cancer cells to suppress exosome biogenesis and secretion .
|
-
- HY-105284
-
|
CP-70429
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Sulopenem (CP-70429) is an orally active, parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria. Sulopenem has the potential for urinary tract infections and intra-abdominal infections treatment. Sulopenem is inactive against Pseudomonas aeruginosa and Xanthomonas maltophilia .
|
-
- HY-12456
-
|
|
Antibiotic
ADC Cytotoxin
DNA Alkylator/Crosslinker
Necroptosis
Apoptosis
|
Cancer
|
|
Duocarmycin SA is an orally active antitumor antibiotic with an IC50 of 10 pM . Duocarmycin SA is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. Duocarmycin SA demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells treated with proton radiation in vitro .
|
-
- HY-B1906
-
|
Agrept; Agrimycin; Streptomycin A
|
Antibiotic
Bacterial
|
Infection
Neurological Disease
|
|
Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes .
|
-
- HY-W040298R
-
|
|
Topoisomerase
Apoptosis
Antibiotic
Bacterial
Mitochondrial Metabolism
Reactive Oxygen Species
|
Infection
Cancer
|
|
Ciprofloxacin (lactate) (Standard) is the analytical standard of Ciprofloxacin (lactate). This product is intended for research and analytical applications. Ciprofloxacin (Bay-09867) lactate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin lactate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin lactate has anti-proliferative activity and induces apoptosis. Ciprofloxacin lactate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity [4].
|
-
- HY-164036
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Lolamicin is a Gram-negative specific antibiotic. Lolamicin is active against more than 130 multidrug-resistant clinical isolates, has shown efficacy in multiple mouse models of acute pneumonia and sepsis infection, and protects the gut microbiome of mice against secondary infection with Clostridium difficile. The selective killing of pathogenic gram-negative bacteria by Lolamicin is a result of the low sequence homology of pathogenic bacteria and symbiotic bacteria. Lolamicin can be used in the study of infection caused by Gram-negative pathogens .
|
-
- HY-B0356AR
-
|
|
Topoisomerase
Apoptosis
Antibiotic
Bacterial
Mitochondrial Metabolism
Reactive Oxygen Species
|
Infection
Cancer
|
|
Ciprofloxacin (monohydrochloride) (Standard) is the analytical standard of Ciprofloxacin (monohydrochloride). This product is intended for research and analytical applications. Ciprofloxacin (Bay-09867) monohydrochloride is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin monohydrochloride induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin monohydrochloride has anti-proliferative activity and induces apoptosis. Ciprofloxacin monohydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity [4].
|
-
- HY-N7112
-
|
Kitasamycin
|
Bacterial
Antibiotic
|
Infection
|
|
Leucomycin (Kitasamycin) is an orally active macrolide antibiotic produced by Streptomyces kitasatoensis. Leucomycin has broad-spectrum antibacterial activities against gram-positive and gram-negative bacteria, mycoplasma, leptospira, spirochaetes, rickettsiae and some larger viruses .
|
-
- HY-16770
-
|
P-005672
|
Antibiotic
Bacterial
DNA/RNA Synthesis
|
Infection
|
|
Sarecycline is an orally effective narrow-spectrum tetracycline derivative antibiotic. Sarecycline has anti-inflammatory activity. Sarecycline inhibits the activity of Gram-positive bacteria and several types of keratobacterium acnes. Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Sarecycline can be used to study moderate to severe acne .
|
-
- HY-13858A
-
|
P-005672 hydrochloride
|
Antibiotic
Bacterial
DNA/RNA Synthesis
|
Infection
|
|
Sarecycline hydrochloride is an orally active narrow-spectrum tetracycline derivative antibiotic. Sarecycline hydrochloride has anti-inflammatory activity. Sarecycline hydrochloride inhibits the activity of Gram-positive bacteria and several types of keratobacterium acnes. Sarecycline hydrochloride interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Sarecycline hydrochloride can be used to study moderate to severe acne
.
|
-
- HY-B0536R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Clinafloxacin (Standard) is the analytical standard of Clinafloxacin. This product is intended for research and analytical applications. Clinafloxacin (AM 1091) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro . Clinafloxacin is against DNA gyrase and topoisomerase IV of S. aureus with IC50 values of 0.92 µg/ml and 1.62 µg/ml, respectively .
|
-
- HY-B0856R
-
|
|
Fungal
Tyrosinase
Antibiotic
|
Infection
|
|
Validamycin A (Standard) is the analytical standard of Validamycin A. This product is intended for research and analytical applications. Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1 μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC50 of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM .
|
-
- HY-15597
-
|
Procoxacin
|
Bacterial
Wnt
β-catenin
Mitophagy
Autophagy
Apoptosis
Antibiotic
Parasite
|
Cancer
|
|
Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, selectively inhibits the growth of gram-positive bacteria. Salinomycin is a potent inhibitor of Wnt/β-catenin signaling, blocks Wnt-induced LRP6 phosphorylation. Salinomycin shows selective activity against human cancer stem cells .
|
-
- HY-A0090R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Nitrofurantoin (Standard) is the analytical standard of Nitrofurantoin. This product is intended for research and analytical applications. Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .
|
-
- HY-B0975R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Penicillin V (Potassium) (Standard) is the analytical standard of Penicillin V (Potassium). This product is intended for research and analytical applications. Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally active antibiotic. Penicillin V Potassium inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V Potassium can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis .
|
-
- HY-162836
-
|
4-O-(Carboxymethyl)-Rifamycin
|
Antibiotic
Bacterial
|
Infection
|
|
Rifamycin B (4-O-(Carboxymethyl)-Rifamycin) is a member of ansamycin antibiotics family with an anti-mycobacterial activity against tuberculosis, leprosy and AIDS-related mycobacterial infections. Rifamycin B is a metabolic product of Nocardia inediterranei, which can yield Rifamycin O and Rifamycin S (HY-125365) by microbial transformation .
|
-
- HY-147349
-
|
|
Beta-lactamase
Bacterial
|
Infection
|
|
ANT3310 sodium is a broad-spectrum covalent Serine β-Lactamase inhibitor, with IC50 values ranging from 1 nM to 175 nM (a panel of Serine β-Lactamase). ANT3310 sodium potentiates activity of β-lactam antibiotics against Carbapenem-Resistant Enterobacterales (CRE) and Acinetobacter baumannii (CRAB). ANT3310 sodium can be used in the research of bacterial infection .
|
-
- HY-P10556
-
|
|
Bacterial
|
Infection
|
|
(KFF)3K is a cell penetrating peptide that can promote the absorption of other antibiotics by disrupting the outer membrane of bacteria. (KFF)3K can be introduced into a hydrocarbon scaffold to induce its antibacterial properties, making it an effective antimicrobial peptide. (KFF)3K can be used in the development of new antimicrobial agents .
|
-
- HY-B0275AR
-
|
|
Bacterial
HSV
Antibiotic
Endogenous Metabolite
|
Infection
|
|
Oxytetracycline (hydrochloride) (Standard) is the analytical standard of Oxytetracycline (hydrochloride). This product is intended for research and analytical applications. Oxytetracycline hydrochloride is an antibiotic belonging to the tetracycline class. Oxytetracycline hydrochloride potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity .
|
-
- HY-B0275R
-
|
|
Bacterial
HSV
Endogenous Metabolite
Antibiotic
|
Infection
|
|
Oxytetracycline (Standard) is the analytical standard of Oxytetracycline. This product is intended for research and analytical applications. Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity .
|
-
- HY-130004
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
MsbA-IN-6 is a potent inhibitor of MsbA. MsbA-IN-6 is an antibiotic. Gram-negative ATP-binding cassette (ABC) transporter MsbA, an essential inner membrane protein, transports lipopolysaccharide from the inner leaflet to the periplasmic face of the inner membrane. MsbA-IN-6 kills Escherichia coli through inhibition of its ATPase and transport activity, with no loss of activity against clinical multidrug-resistant strains .
|
-
- HY-N0565AR
-
|
|
MMP
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
|
Doxycycline (hydrochloride) (Standard) is the analytical standard of Doxycycline (hydrochloride). This product is intended for research and analytical applications. Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hydrochloride shows antibacterial activity and anti-cancer cell proliferation activity [4] .
|
-
- HY-N0565R
-
|
|
MMP
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
|
Doxycycline (Standard) is the analytical standard of Doxycycline. This product is intended for research and analytical applications. Doxycycline, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline shows antibacterial activity and anti-cancer cell proliferation activity [4] .
|
-
- HY-B0975AR
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Penicillin V (Standard) is the analytical standard of Penicillin V. This product is intended for research and analytical applications. Penicillin V (Phenoxymethylpenicillin) is a potent and orally active antibiotic. Penicillin V shows antibacterial activity for Streptococci, Clostridium difficile and staphylococcus aureus. Penicillin V has the potential for the research of otitis, sinusitis, pharyngitis and tonsillitis [4].
|
-
- HY-B1374S1
-
|
(-)-Florfenicol-d3; SCH-25298-d3
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Florfenicol-d3 is the deuterium labeled Florfenicol. Florfenicol, a commonly used veterinary antibiotic, is currently indicated for bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g.
|
-
- HY-B1831
-
|
LY 333328; Orbactiv
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
|
Oritavancin (LY 333328), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .
|
-
- HY-B1286
-
|
Sodium piperacillin
|
Bacterial
Antibiotic
Penicillin-binding protein (PBP)
|
Infection
Cancer
|
|
Piperacillin sodium is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .
|
-
- HY-B1257
-
|
Sodium cefmetazole
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
|
-
- HY-B1595
-
|
CS 1170
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Cefmetazole (CS 1170) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative and anaerobic bacteria. Cefmetazole binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
|
-
- HY-N125722
-
|
Aabomycin A1
|
ATP Synthase
Antibiotic
|
Infection
|
|
Venturicidin A (Aabomycin A1), from actinomycetes, is a membrane-active natural product inhibitor of ATP synthase. Venturicidin A potentiates the aminoglycoside antibiotic gentamicin against multidrug-resistant clinical isolates of Staphylococcus, Enterococcus, and Pseudomonas aeruginosa. Venturicidin A shows noticeable toxicity toward human embryonic-kidney (HEK)cells with an IC50 of 31 μg/mL.
|
-
- HY-W062216
-
|
|
Bacterial
Arginase
|
Infection
|
|
2-Aminoimidazole is a potent antibiofilm agent that can be used as an adjuvant to antimicrobial. 2-aminoimidazoles disrupts the ability of bacteria to protect themselves by inhibiting biofilm formation and genetically-encoded antibiotic resistance traits. 2-Aminoimidazole is also a weak noncompetitive inhibitor of human arginase I with a Ki of 3.6 mM .
|
-
- HY-B0479S1
-
|
Thiophenicol-d3-1; Dextrosulphenidol-d3-1
|
Isotope-Labeled Compounds
|
Infection
|
|
Thiamphenicol-d3-1 (Thiophenicol-d3-1; Dextrosulphenidol-d3-1) is the deuterium-labeled Thiamphenicol (HY-B0479) . Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
|
-
- HY-B1906R
-
|
|
Antibiotic
Bacterial
|
Infection
Neurological Disease
|
|
Streptomycin (Standard) is the analytical standard of Streptomycin. This product is intended for research and analytical applications. Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes .
|
-
- HY-151944
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Antibacterial agent 128 is a siderophore analog-Ciprofloxacin (Ciprofloxacin (HY-B0356)) conjugate with a cleavable linker. Antibacterial agent 128 shows antibiotic activities against P. aeruginosa (MIC values of 0.25-64 μg/mL) and B. pseudomallei (MIC values of 1-32 μg/mL) .
|
-
- HY-B1831A
-
|
LY333328 diphosphate
|
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Oritavancin diphosphate (LY333328 diphosphate), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .
|
-
- HY-N0565BR
-
|
|
Antibiotic
MMP
Bacterial
Parasite
|
Infection
Cancer
|
|
Doxycycline hyclate (Standard) is the analytical standard of Doxycycline hyclate. This product is intended for research and analytical applications. Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hyclate shows antibacterial activity and anti-cancer cell proliferation activity .
|
-
- HY-B0275BR
-
|
|
Bacterial
HSV
Antibiotic
Endogenous Metabolite
|
Infection
|
|
Oxytetracycline (dihydrate) (Standard) is the analytical standard of Oxytetracycline (dihydrate). This product is intended for research and analytical applications. Oxytetracycline dihydrate is an antibiotic belonging to the tetracycline class. Oxytetracycline dihydrate potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline dihydrate is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline dihydrate also possesses anti-HSV-1 activity .
|
-
- HY-125365R
-
|
|
Bacterial
Reactive Oxygen Species
Antibiotic
|
Infection
|
|
Rifamycin S (Standard) is the analytical standard of Rifamycin S. This product is intended for research and analytical applications. Rifamycin S, a quinone, is an antibiotic against Gram-positive bacteria (including MRSA). Rifamycin S is the oxidized forms of a reversible oxidation-reduction system involving two electrons. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. Rifamycin S can be used for tuberculosis and leprosy .
|
-
- HY-P1649B
-
|
NAB741 acetate
|
Bacterial
Antibiotic
|
Infection
|
|
SPR741 acetate (NAB741 acetate) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 acetate increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 acetate inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 acetate .
|
-
- HY-N6693
-
|
NSC 122023
|
Apoptosis
Antibiotic
Autophagy
Fungal
|
Infection
Others
Cancer
|
|
Valinomycin is a potassium-specific ionophore, the valinomycin-K + complex can be incorporated into biological bilayer membranes with the hydrophobic surface of valinomycin, destroys the normal K + gradient across the membrane, and as a result kills the cells, incorporating into liposomes can significantly reduces the cytotoxicity and enhances the targeting effect. Valinomycin exhibits antibiotic, antifungal, antiviral, antitumor and insecticidal efficacy, thus can be used for relevant research .
|
-
- HY-P1649
-
|
NAB741
|
Bacterial
Antibiotic
|
Infection
|
|
SPR741 (NAB741) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 .
|
-
- HY-118230
-
|
Rubiflavin B
|
Antibiotic
|
Infection
|
|
Kidamycin is a polymycin antibiotic that can be extracted from the antitumor antibiotic rubraflavin .
|
-
- HY-13858AR
-
|
|
Antibiotic
Bacterial
DNA/RNA Synthesis
|
Infection
|
|
Sarecycline (hydrochloride) (Standard) is the analytical standard of Sarecycline (hydrochloride). This product is intended for research and analytical applications. Sarecycline hydrochloride is an orally active narrow-spectrum tetracycline derivative antibiotic. Sarecycline hydrochloride has anti-inflammatory activity. Sarecycline hydrochloride inhibits the activity of Gram-positive bacteria and several types of keratobacterium acnes. Sarecycline hydrochloride interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Sarecycline hydrochloride can be used to study moderate to severe acne .
|
-
- HY-B1831AR
-
|
|
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Oritavancin (diphosphate) (Standard) is the analytical standard of Oritavancin (diphosphate). Oritavancin diphosphate (Standard), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate (Standard) shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate (Standard) inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate (Standard) inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate (Standard) enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .
|
-
- HY-B1923A
-
|
Pipracil hydrate
|
Antibiotic
Bacterial
Beta-lactamase
Penicillin-binding protein (PBP)
|
Infection
Cancer
|
|
Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin hydrate is most commonly used in combination with the β-lactamase inhibitor Tazobactam (HY-B1418) .
|
-
- HY-B0519B
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
|
-
- HY-B0519A
-
Tylosin
1 Publications Verification
|
Bacterial
Antibiotic
|
Infection
|
|
Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
|
-
- HY-15142
-
|
Hydroxydaunorubicin hydrochloride; ADR
|
Topoisomerase
ADC Cytotoxin
AMPK
Autophagy
Apoptosis
HIV
HBV
Mitophagy
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride; ADR), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy .
|
-
- HY-B0398
-
|
|
Bacterial
Antibiotic
Topoisomerase
|
Infection
|
|
Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria .
|
-
- HY-P1649A
-
|
NAB741 TFA
|
Bacterial
Antibiotic
|
Infection
|
|
SPR741 TFA (NAB741 TFA) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 TFA increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 TFA inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 TFA .
|
-
- HY-130224
-
|
|
Antibiotic
|
Infection
|
|
Altromycin C is a pluramycin-like antibiotic with antibacterial activity. Altromycin C is related to pluramycin-type antibiotics but is structurally distinct. The biological activity of Altromycin C makes it an antibiotic complex worthy of attention .
|
-
- HY-113678
-
|
Polymyxin E
|
Antibiotic
Bacterial
|
Infection
|
|
Colistin (Polymyxin E) is an orally active polypeptide antibiotic. Colistin has excellent activity against various Gram-negative rod-shaped bacteria, including multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae. Colistin is associated with nephrotoxicity. Colistin can be used for the research of infections caused by Gram-negative bacilli .
|
-
- HY-121333
-
|
|
Antibiotic
Wnt
β-catenin
|
Infection
Neurological Disease
Cancer
|
|
Dinactin, an antibiotic ionophore produced by Streptomyces species, as an effective small molecule targeting Wnt/β-catenin signaling pathway in cancer cells. Dinactin shows marked inhibition of HCT-116 cell growth with an IC50 of 1.1 µM. Dinactin shows anti-proliferative activity against the cancer cells in apoptosis-independent manner. Dinactin is also an effective agent for the research of neuropathic pain .
|
-
- HY-B1286R
-
|
|
Bacterial
Antibiotic
Penicillin-binding protein (PBP)
|
Infection
|
|
Piperacillin (sodium) (Standard) is the analytical standard of Piperacillin (sodium). This product is intended for research and analytical applications. Piperacillin sodium is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .
|
-
- HY-B0398A
-
|
|
Bacterial
Antibiotic
Topoisomerase
|
Infection
|
|
Nalidixic acid sodium salt, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria .
|
-
- HY-B0519
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
|
-
- HY-B1257R
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Cefmetazole (sodium) (Standard) is the analytical standard of Cefmetazole (sodium). This product is intended for research and analytical applications. Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
|
-
- HY-113700
-
|
|
Antibiotic
|
Cancer
|
|
PD 116779 is an Antibiotic with anticancer activity. PD 116779 demonstrates moderate cytotoxicity against L1210 lymphocytic leukemia and HCT-8 human colon adenocarcinoma cell lines with IC50 values of 3.55x10 -7 and 4.08x10 -7 M, respectively .
|
-
- HY-B1923
-
|
Pipracil
|
Antibiotic
Bacterial
Beta-lactamase
Penicillin-binding protein (PBP)
|
Infection
Cancer
|
|
Piperacillin is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .
|
-
- HY-18324
-
|
REP-3123
|
Antibiotic
|
Inflammation/Immunology
|
|
CRS3123 is a potent and orally active narrow-spectrum antibiotic. CRS3123 inhibits bacterial methionyl-tRNA synthetase. CRS3123 has potent activity against Clostridium difficile (C. difficile) and aerobic Gram-positive bacteria but little activity against Gram-negative bacteria, including anaerobes. CRS3123 has the potential for the research of C. difficile infections .
|
-
- HY-P2302
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Defensin HNP-3 human is a cytotoxic antibiotic peptide known as "defensin". Defensin HNP-3 human has inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Defensin HNP-3 human is initially synthesized as the 94 amino acids preproHNP(1-94), which is hydrolyzed to proHNP(20-94) and converted to mature HNP(65-94) after the removal of anion precursors .
|
-
- HY-114979
-
|
|
Antibiotic
Fungal
Apoptosis
|
Infection
Cancer
|
|
Pyoluteorin is an antibiotic that inhibits Oomycete fungi, including the plant pathogen Pythium ultimum, and suppresses plant diseases caused by this fungus . Pyoluteorin induces human triple-negative breast cancer MDA-MB-231 cells apoptosis in vitro. Pyoluteorin can be used for the research of human triple-negative breast cancer .
|
-
- HY-B1118A
-
|
RP-14539 hemihydrate; PM-185184 hemihydrate
|
Antibiotic
Bacterial
Parasite
|
Infection
|
|
Secnidazole (RP-14539) hemihydrate is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole hemihydrate, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole hemihydrate has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole hemihydrate can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .
|
-
- HY-B1118
-
|
RP-14539; PM-185184
|
Parasite
Antibiotic
Bacterial
|
Infection
|
|
Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .
|
-
- HY-103251R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cefalonium (dihydrate) (Standard) is the analytical standard of Cefalonium (dihydrate). This product is intended for research and analytical applications. Cefalonium dihydrate is a cephalosporin antibiotic. Cefalonium (dihydrate) is effective against Staphylococcus aureus. Cefalonium (dihydrate) has anti-inflammatory and antibacterial activities .
|
-
- HY-113604
-
|
|
TGF-β Receptor
|
Cancer
|
Pentabromopseudilin (PBrP) is a marine antibiotic isolated from the marine bacteria Pseudomonas bromoutilis and Alteromonas luteoviolaceus. PBrP exhibits antimicrobial, anti-tumour and phytotoxic activities. PBrP is a reversible and allosteric inhibitor of myosin Va (MyoVa). PBrP also is a potent inhibitor of transforming growth factor-β (TGF-β) activity. PBrP can be used for the research of fibrotic diseases and cancer .
|
-
- HY-P1674A
-
|
POL7080 TFA
|
Bacterial
Antibiotic
|
Infection
|
|
Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC50 and MIC90 values both of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance .
|
-
- HY-P1674
-
|
POL7080
|
Bacterial
Antibiotic
|
Infection
|
|
Murepavadin (POL7080), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with both MIC50 and MIC90 values of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance .
|
-
- HY-126629
-
|
|
Bacterial
|
Infection
|
|
Antibacterial agent 12, a biaryloxazolidinone analogue, is an antibacterial agent against antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria .
|
-
- HY-125745
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Loloatin B 10 is an antibiotic, which exhibits antibacterial efficacy against gram positive antibiotic resistant human pathogens .
|
-
- HY-110271
-
|
|
Antibiotic
|
Others
|
|
N-Acetylpuromycin is a inactive form of the antibiotic puromycin. N-Acetylpuromycin is the last intermediate of the puromycin antibiotic biosynthetic pathway in Streptomyces alboniger .
|
-
- HY-15142A
-
|
Hydroxydaunorubicin
|
ADC Cytotoxin
Antibiotic
Bacterial
Topoisomerase
AMPK
HIV
Autophagy
Mitophagy
Apoptosis
HBV
|
Infection
Cancer
|
|
Doxorubicin (Hydroxydaunorubicin), a broad-spectrum anthracycline antibiotic with cytotoxic properties, is an anti-cancer chemotherapy agent. Doxorubicin has fluorescence properties. Doxorubicin inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DNA replication. Doxorubicin reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin induces apoptosis and autophagy . Doxorubicin inhibits human DNA topoisomerase I with an IC50 of 0.8 μM .
|
-
- HY-A0098
-
|
|
Bacterial
Fungal
Influenza Virus
Antibiotic
|
Infection
Inflammation/Immunology
Cancer
|
|
Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity .Tunicamycin increases exosome release in cervical cancer cells .
|
-
- HY-15142R
-
|
|
Topoisomerase
ADC Cytotoxin
AMPK
Autophagy
Apoptosis
HIV
HBV
Mitophagy
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Doxorubicin hydrochloride (Standard) is the analytical standard of Doxorubicin hydrochloride. This product is intended for research and analytical applications. Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy .
|
-
- HY-B0198A
-
-
- HY-B0198
-
-
- HY-B0519AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tylosin (Standard) is the analytical standard of Tylosin. This product is intended for research and analytical applications. Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
|
-
- HY-B0519BR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tylosin (phosphate) (Standard) is the analytical standard of Tylosin (phosphate). This product is intended for research and analytical applications. Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
|
-
- HY-P99551
-
|
KBSA301; AR-301
|
Antibiotic
|
Infection
|
|
Tosatoxumab (AR-301; KBSA301) is a human immunoglobulin G1 monoclonal antibody that specifically neutralizes alpha-toxin (alpha-hemolysin; Hla) of S. aureus. Tosatoxumab binds to an N-terminal epitope of alpha-toxin, thereby preventing functional toxin pore oligomerisation. Tosatoxumab has the potential for passive immunotherapy in the S. aureus pneumonia as an adjunctive therapy to standard antibiotic agent .
|
-
- HY-N13869
-
-
- HY-B1381A
-
|
FR-17027 trihydrate; FK-027 trihydrate; CL-284635 trihydrate
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
Cancer
|
|
Cefixime trihydrate (FR-17027 trihydrate) is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections .
|
-
- HY-B1381
-
|
FR-17027; FK-027; CL-284635
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Cefixime (FR-17027) is an orally active antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections .
|
-
- HY-120383
-
|
Sacromycin; U-4761
|
Antibiotic
Bacterial
|
Infection
|
|
Amicetin is a potent antibiotic. Amicetin shows antibiotic activities against gram-positive bacteria. Amicetin inhibits protein synthesis .
|
-
- HY-133704
-
|
|
Bacterial
Fungal
Antibiotic
|
Infection
|
|
Pyrrolnitrin is an antibiotic isolated from Pseudomonas pyrrocinia. Pyrrolnitrin shows a broad spectrum of antibiotic activity against fungi, yeast and gram-positive bacteria .
|
-
- HY-B0398R
-
|
|
Bacterial
Antibiotic
Topoisomerase
|
Infection
|
|
Nalidixic acid (Standard) is the analytical standard of Nalidixic acid. This product is intended for research and analytical applications. Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria .
|
-
- HY-B1118R
-
|
|
Parasite
Antibiotic
Bacterial
|
Infection
|
|
Secnidazole (Standard) is the analytical standard of Secnidazole. This product is intended for research and analytical applications. Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .
|
-
- HY-101593
-
-
- HY-B1923R
-
|
|
Bacterial
Antibiotic
Beta-lactamase
Penicillin-binding protein (PBP)
|
Infection
Cancer
|
|
Piperacillin (Standard) is the analytical standard of Piperacillin. This product is intended for research and analytical applications. Piperacillin is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .
|
-
- HY-B0519R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tylosin (tartrate) (Standard) is the analytical standard of Tylosin (tartrate). This product is intended for research and analytical applications. Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
|
-
- HY-100577
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Ticarcillin sodium is an injectable antibiotic for the treatment of Gram-negative bacteria, particularly Pseudomonas aeruginosa. It is also one of the few antibiotics capable of treating Stenotrophomonas maltophilia infections .
|
-
- HY-U00154
-
-
- HY-N12257
-
|
|
Fungal
Cytochrome P450
|
Infection
|
|
Antimycin A2 is the component of the antibiotic antimycin A. Antimycin A is an antibiotic, that exhibits inhibitory activity against fungi and some insects through inhibition of respiration and cytochrome b reoxidation .
|
-
- HY-106257A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Ceftolozane TFA is a cephalosporin antibiotic that can be used to inhibit Gram-negative bacterial infections. Ceftolozane TFA can be used to synthesize new antibiotic that are more potent and safer .
|
-
- HY-B0712A
-
|
Ro 13-9904 sodium hydrate
|
Bacterial
Antibiotic
GSK-3
Aurora Kinase
|
Infection
Cancer
|
|
Ceftriaxone sodium hydrate (Ro 13-9904 sodium hydrate) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium hydrate is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone sodium hydrate is an inhibitor of Aurora B. Ceftriaxone sodium hydrate has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium hydrate can be used in the study of bacterial infections and meningitis .
|
-
- HY-B0712
-
|
Ro 13-9904 free acid
|
Bacterial
Antibiotic
GSK-3
Aurora Kinase
|
Infection
Inflammation/Immunology
Cancer
|
|
Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .
|
-
- HY-A0170
-
|
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
|
Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 .
|
-
- HY-103399
-
|
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
|
Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 .
|
-
- HY-B0198R
-
-
- HY-W764182
-
|
|
Antibiotic
|
Infection
|
|
Cephalosporinase, bacillus are enzymes produced by bacillus, inactivated and degrade the ability of the cephalosporin class of antibiotics. Cephalosporins are a class of β-lactam antibiotics that are widely used to treat bacterial infections .
|
-
- HY-N0113BR
-
-
- HY-N0113B
-
|
Ordenina hydrochloride; Peyocactine hydrochloride
|
Antibiotic
|
Infection
|
|
Hordenine (hydrochloride), an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .
|
-
- HY-163190
-
|
|
Bacterial
|
Infection
|
|
NDM-1 inhibitor-4 (compound 27) is a NDM-1 inhibitor with Ki of 1.7 μM. NDM-1 inhibitor-4 has antimicrobial effect .
|
-
- HY-129475
-
-
- HY-B0671
-
-
- HY-125682
-
-
- HY-122384
-
-
- HY-17028
-
-
- HY-101818
-
-
- HY-125561
-
-
- HY-N8381
-
-
- HY-126866
-
|
|
Bacterial
|
Infection
|
|
Lankacidin C 8-acetate is an antibiotic with antibacterial activity. Lankacidin C 8-acetate, as a component of the Lankacidin group (T-2636) antibiotics, shows inhibitory effects against specific bacteria. Lankacidin C 8-acetate can generate other esterates by reacting with different acyl donors, indicating its importance in the synthesis of antibiotics .
|
-
- HY-B0198AR
-
|
|
Antibiotic
Bacterial
Penicillin-binding protein (PBP)
5-HT Receptor
|
Infection
Neurological Disease
Inflammation/Immunology
|
|
Cefaclor (monohydrate) (Standard) is the analytical standard of Cefaclor (monohydrate). This product is intended for research and analytical applications. Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections .
|
-
- HY-B0712B
-
|
Ro 13-9904
|
Antibiotic
GSK-3
Bacterial
Aurora Kinase
|
Infection
Inflammation/Immunology
Cancer
|
|
Ceftriaxone sodium salt (Ro 13-9904) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium salt is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone sodium salt is an inhibitor of Aurora B. Ceftriaxone sodium salt has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium salt can be used in the study of bacterial infections and meningitis .
|
-
- HY-121222
-
|
|
PI3K
Apoptosis
|
Cancer
|
|
alpha-Bisabolol, an orally active sesquiterpene alcohol, induces cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol exerts a protective action against Cisplatin (HY-17394)-induced nephrotoxicity by mitigating inflammation and oxidative stress through the inhibition of NFκB activation. alpha-Bisabolol exhibits anti-inflammatory, analgesic, antibiotic and anticancer activities .
|
-
- HY-N7141
-
-
- HY-N14909
-
-
- HY-P10182
-
-
- HY-W747994
-
-
- HY-B0724A
-
|
T-3762; Pazufloxacin methanesulfonate; Pazufloxacin mesilate
|
Bacterial
Antibiotic
|
Infection
|
|
Pazufloxacin (T-3761) mesylate is a fluoroquinolone antibiotic.
|
-
- HY-101575
-
|
Acetylkelfizina; Acetylsulfamethoxypyrazine; FI6073
|
Bacterial
Antibiotic
|
Infection
|
|
Acetylazide is a synthetic broad-spectrum bacteriostatic antibiotic.
|
-
- HY-B0724B
-
-
- HY-131477A
-
-
- HY-P5707
-
-
- HY-A0062
-
|
HMR3647; RU66647
|
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Telithromycin (HMR3647) is a novel ketolide antibiotic that structurally resembles macrolides. Telithromycin belongs to the ketolide family that is characterized by a keto group at position 3 of the macrolide ring and is active against bacteria causing community-acquired pneumonia, acute exacerbation of chronic bronchitis, and acute sinusitis. Telithromycin also has similar immunomodulatory effects as macrolides. Telithromycin can be used for the research of respiratory infections including bronchial asthma .
|
-
- HY-105099
-
|
KRM-1648; ABI-1648
|
DNA/RNA Synthesis
Bacterial
|
Infection
Inflammation/Immunology
|
|
Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase . Rifalazil (KRM-1648; ABI-1648) is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis with MIC values from 0.00025 to 0.0025 μg/ml . Rifalazil (KRM-1648; ABI-1648) has the potential for the treatment of Chlamydia infection, Clostridium difficile associated diarrhea (CDAD), and tuberculosis (TB) .
|
-
- HY-W018677S
-
|
|
Antibiotic
|
Infection
|
|
Quinoxaline-d4 is the deuterium labeled Quinoxaline[1]. Quinoxaline is a chemical compound that acts as an intermediate for anti-tuberculosis agent Pyrazinamide. Quinoxaline presents a structure that is similar to quinolone antibiotics[2].
|
-
- HY-N6737
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Aureothricin is a dithiolopyrrolone (DTP) antibiotic first isolated from Streptomyces and exhibits relatively broad-spectrum antibiotic activity. Aureothricin can inhibit adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin .
|
-
- HY-112665
-
|
Streptogramin; Mikamycin; RP 7293
|
Antibiotic
Bacterial
|
Infection
|
|
Virginiamycin complex contains two streptogramin antibiotics, virginiamycin M1 and virginiamycin S1 produced by S. virginiae. As a complex, the two antibiotics act synergistically to irreversibly inhibit protein synthesis in bacteria .
|
-
- HY-N6769
-
|
Monorden
|
HSP
Bacterial
Antibiotic
Parasite
|
Infection
|
|
Radicicol is an inhibitor of Hsp90 with an IC50 value < 1 μM, and leads to proteasomal degradation . Radicicol exhibits inhibition on PDK with IC50s of 230 μM (PDK1) and 400 μM (PDK3). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB . Radicicol is also an inhibitor of fat mass and obesity-associated protein (FTO), with an IC50 value of 16.04 μM .
|
-
- HY-B0712AR
-
|
|
Bacterial
Antibiotic
GSK-3
Aurora Kinase
|
Infection
Cancer
|
|
Ceftriaxone (sodium hydrate) (Standard) is the analytical standard of Ceftriaxone (sodium hydrate). This product is intended for research and analytical applications. Ceftriaxone sodium hydrate (Ro 13-9904 sodium hydrate) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium hydrate is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone sodium hydrate is an inhibitor of Aurora B. Ceftriaxone sodium hydrate has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium hydrate can be used in the study of bacterial infections and meningitis .
|
-
- HY-A0170R
-
|
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
|
Trovafloxacin (Standard) is the analytical standard of Trovafloxacin. This product is intended for research and analytical applications. Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 .
|
-
- HY-B1434
-
|
7-ACA
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
7-aminocephalosporanic acid (7-ACA) is a HSP90β inhibitor and an antibiotic. 7-Aminocephalosporanic acid is the core chemical structure of the synthesis of cephalosporin antibiotics and an effective β-lactamase inhibitor .
|
-
- HY-129329
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Lankamycin, a macrolide antibiotic, shows moderate antimicrobial activity against several gram-positive bacteria, acting as a synergistic pair with carbocyclic antibiotic Lankacidin C (HY-121412) by binding to the ribosome exit tunnel .
|
-
- HY-E70012
-
|
|
Endogenous Metabolite
|
Infection
Metabolic Disease
|
|
Penicillinase is a beta-lactamase. beta-lactamase enzymes inactivate beta-lactam antibiotics by hydrolyzing the peptide bond of the characteristic four-membered beta-lactam ring rendering the antibiotic ineffective .
|
-
- HY-A0088A
-
-
- HY-B1128
-
-
- HY-133056
-
-
- HY-B0343A
-
|
A-56620 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Sarafloxacin (hydrochloride) (A-56620 (hydrochloride)) is a quinolone antibiotic agent.
|
-
- HY-A0071
-
-
- HY-127075
-
-
- HY-B1894A
-
-
- HY-19655
-
-
- HY-B1463
-
-
- HY-P5577
-
-
- HY-B1781A
-
|
Sulfachlorpyridazine sodium
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfachloropyridazine (sodium) is a sulfonamide antibiotic that inhibits bacterial growth .
|
-
- HY-B1128A
-
-
- HY-128459
-
|
|
Drug Metabolite
|
Others
|
|
N-Demethylerythromycin A is a metabolite of Erythromycin A. Erythromycin A is an antibiotic .
|
-
- HY-B0472
-
-
- HY-122035
-
|
|
Bacterial
|
Infection
|
|
Flambalactone is a degradation product formed by methanolysis of the antibiotic flambamycin.
|
-
- HY-B1218
-
|
|
Cytochrome P450
Antibiotic
Bacterial
Necroptosis
Apoptosis
|
Infection
Cardiovascular Disease
|
|
Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion .
|
-
- HY-B0239
-
|
|
Antibiotic
Bacterial
HIF/HIF Prolyl-Hydroxylase
VEGFR
Autophagy
Apoptosis
Beclin1
JNK
Akt
MMP
|
Infection
Cancer
|
|
Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research .
|
-
- HY-B1381R
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Cefixime (Standard) is the analytical standard of Cefixime. This product is intended for research and analytical applications. Cefixime (FR-17027) is an orally active antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections .
|
-
- HY-119206
-
|
|
Antibiotic
|
Others
|
|
Sulbenicillin is an antibiotic that, in a study of its activity against Pseudomonas aeruginosa infection in mice, showed differences in activity against certain strains compared to other antibiotics, and activity against gentamicin-resistant strains was affected by the strain's own resistance.
|
-
- HY-129788
-
|
|
Antibiotic
|
Others
|
|
Deltamycin A1 is a compound with antibacterial activity. Its structure belongs to the basic macrolide antibiotic family and is different from several other antibiotics of similar structure. Its structure was determined by spectroscopic properties and verified by chemical synthesis.
|
-
- HY-A0088
-
|
Cefotaxim sodium; HR-756 sodium
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Cefotaxime (Cefotaxim) sodium, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
|
-
- HY-W016420
-
|
MK-0955 sodium
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Fosfomycin (MK-0955) sodium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin sodium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-B1075A
-
|
MK-0955
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-P2020
-
|
|
Bacterial
|
Infection
|
|
Berninamycin A is a cyclic thiopeptide antibiotic first isolated from S. bernensis. It inhibits protein biosynthesis in Gram positive bacteria through binding with ribosomal subunits. Cyclic thiopeptide antibiotics, including berninamycin A, induce the transcriptional activator TipA in Streptomyces.
|
-
- HY-B1466
-
|
BAY-f 1353 sodium
|
Bacterial
Antibiotic
|
Infection
|
|
Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research .
|
-
- HY-B1466A
-
|
BAY-f 1353
|
Antibiotic
Bacterial
|
Infection
|
|
Mezlocillin (BAY-f 1353) is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin is active against both gram-negative and gram-positive bacteria. Mezlocillin can be used in bacterial infection research .
|
-
- HY-17624
-
|
Neomycin B; Fradiomycin B
|
Bacterial
Antibiotic
|
Infection
|
|
Framycetin (Neomycin B), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections .
|
-
- HY-B1149A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Bacampicillin hydrochloride is a penicillin antibiotic, is a prodrug of ampicillin with improved oral bioavailability.
|
-
- HY-16251A
-
|
|
Bacterial
|
Infection
|
|
Hetacillin is a beta-lactam antibiotic that is part of the aminopenicillin family.
|
-
- HY-B0269
-
-
- HY-17506A
-
-
- HY-119764
-
|
|
Antibiotic
|
Others
|
|
Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME) .
|
-
- HY-B0458A
-
-
- HY-B1743
-
|
CL13900
|
Bacterial
Antibiotic
Parasite
|
Infection
|
|
Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.
|
-
- HY-123474
-
-
- HY-117849
-
|
|
Antibiotic
|
Infection
|
|
Neutramycin is a neutral macrolide antibiotic with a complex composition and classification .
|
-
- HY-B0458
-
-
- HY-N5172
-
-
- HY-N6665A
-
-
- HY-B1387
-
-
- HY-125552
-
-
- HY-121245
-
-
- HY-131093
-
|
Enramycin
|
Antibiotic
|
Infection
|
|
Enduracidin (Enramycin) is a polypeptide antibiotic produced by Streptomyces fungicides .
|
-
- HY-109755
-
-
- HY-N14913
-
-
- HY-17506
-
-
- HY-N13875
-
-
- HY-B1149
-
-
- HY-148910
-
|
|
Antibiotic
|
Infection
|
|
Paromamine is an antibiotic that recognizes ribosomal RNA (rRNA) components .
|
-
- HY-B1075
-
|
MK-0955 calcium
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Fosfomycin (MK-0955) calcium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin calcium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-B0609
-
|
MK-0955 tromethamine
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Fosfomycin (MK-0955) tromethamine is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin tromethamine shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-B1907A
-
|
Rifamycin SV
|
Bacterial
Antibiotic
|
Infection
|
|
Rifamycin (Rifamycin SV) belongs to the family of ansamycin antibiotics and has been isolated from the fermentation of A. mediterranei or its mutants. Rifamycin displays a broad spectrum of antibiotic activity against Gram-positive and, to a lesser extent, Gram-negative bacteria .
|
-
- HY-B1381AR
-
|
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
Cancer
|
|
Cefixime (trihydrate) (Standard) is the analytical standard of Cefixime (trihydrate). This product is intended for research and analytical applications. Cefixime trihydrate (FR-17027 trihydrate) is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections .
|
-
- HY-17558
-
|
Nebramycin II
|
Bacterial
Antibiotic
|
Infection
|
|
Apramycin (Nebramycin II) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic .
|
-
- HY-B1907
-
|
Rifamycin SV sodium
|
Bacterial
Antibiotic
|
Infection
|
|
Rifamycin sodium (Rifamycin SV monosodium) belongs to the family of ansamycin antibiotics and has been isolated from the fermentation of A. mediterranei or its mutants. Rifamycin sodium displays a broad spectrum of antibiotic activity against Gram-positive and, to a lesser extent, Gram-negative bacteria .
|
-
- HY-B1175
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
(2S,5R,6R)-Ticarcillin disodium is an injectable antibiotic for the treatment of Gram-negative bacteria, particularly Pseudomonas aeruginosa. It is also one of the few antibiotics capable of treating Stenotrophomonas maltophilia infections.
|
-
- HY-122146
-
-
- HY-N5173
-
-
- HY-129339
-
|
|
Fungal
|
Infection
Cancer
|
|
Akrobomycin is an anthracycline antibiotic. Akrobomycin shows antimicrobial and antitumor activities .
|
-
- HY-B1743A
-
-
- HY-131150
-
-
- HY-13644A
-
|
Spanidin; NKT-01; BMS181173
|
Antibiotic
|
Inflammation/Immunology
Cancer
|
|
Gusperimus trihydrochloride (Spanidin) is a derivative of the antitumor antibiotic spergualin with immunosuppressant activity .
|
-
- HY-B0490
-
-
- HY-141441
-
|
|
Bacterial
|
Infection
|
|
Novobiocic acid is an aglycone form of the antibiotic Novobiocin (HY-B0425).
|
-
- HY-107213
-
-
- HY-N6665
-
-
- HY-17624A
-
|
Neomycin B sulfate; Fradiomycin B sulfate
|
Antibiotic
Bacterial
|
Infection
|
|
Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin sulfate, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections .
|
-
- HY-168204
-
|
|
Bacterial
Fungal
|
Infection
|
|
3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid (compound J1) is a potent antimicrobial agent. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid shows anti-gram-positive bacteria and fungi activity. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid can be used as antibiotic adjuvants. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic disrupts the bacterial cell membrane, inserts into the DNA, and binds to DNA gyrase. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic reduces microbial count in a mouse MRSA skin infection model and accelerates wound healing .
|
-
- HY-B0239R
-
|
|
Antibiotic
Bacterial
HIF/HIF Prolyl-Hydroxylase
VEGFR
Autophagy
Apoptosis
Beclin1
JNK
Akt
MMP
|
Infection
Cancer
|
|
Chloramphenicol (Standard) is the analytical standard of Chloramphenicol. This product is intended for research and analytical applications. Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research .
|
-
- HY-B1218R
-
|
|
Cytochrome P450
Antibiotic
Bacterial
Necroptosis
Apoptosis
|
Infection
Cardiovascular Disease
|
|
Sulfaphenazole (Standard) is the analytical standard of Sulfaphenazole. This product is intended for research and analytical applications. Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion .
|
-
- HY-A0062R
-
|
|
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Telithromycin (Standard) is the analytical standard of Telithromycin. This product is intended for research and analytical applications. Telithromycin (HMR3647) is a novel ketolide antibiotic that structurally resembles macrolides. Telithromycin belongs to the ketolide family that is characterized by a keto group at position 3 of the macrolide ring and is active against bacteria causing community-acquired pneumonia, acute exacerbation of chronic bronchitis, and acute sinusitis. Telithromycin also has similar immunomodulatory effects as macrolides. Telithromycin can be used for the research of respiratory infections including bronchial asthma .
|
-
- HY-B0712S1
-
|
Ro 13-9904-13C2,d3 triethylammonium salt
|
Antibiotic
Aurora Kinase
GSK-3
Bacterial
Isotope-Labeled Compounds
|
Infection
Inflammation/Immunology
Cancer
|
|
Ceftriaxone- 13C2,d3 triethylammonium salt is 13C and deuterated labeled Ceftriaxone (HY-B0712). Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC50 value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .
|
-
- HY-126662
-
|
|
Bacterial
|
Infection
|
|
Netzahualcoyone is a triterpenoid compound isolated from the Celastraceae plant family. Netzahualcoyone exhibits broad-spectrum antibiotic activity against Gram-positive bacteria and yeasts, but is not active against Gram-negative bacteria. Netzahualcoyone can be utilized in the development of antibiotics and for studying antimicrobial mechanisms .
|
-
- HY-10394
-
|
PNU-100766
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics .
|
-
- HY-118029
-
|
|
Antibiotic
|
Infection
|
|
Saroaspidin A is an antibiotic, which can be isolated from Hypericum japonicum thunb .
|
-
- HY-125074
-
|
|
Antibiotic
|
Infection
|
|
PNU 142300 is an inactive metabolite of the oxazolidinone antibiotic Linezolid (HY-10394).
|
-
- HY-U00214
-
|
R835; S25930
|
Antibiotic
Bacterial
|
Infection
|
|
Ibafloxacine (R835) is a fluoroquinolone antibiotic agent that is developed exclusively for veterinary use.
|
-
- HY-W714019
-
-
- HY-B0465
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Oxacillin sodium monohydrate is an antibiotic similar to Flucloxacillin used in resistant staphylococci infections study .
|
-
- HY-129814
-
-
- HY-B1300
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefonicid sodium is a broadspectrum cephalosporin antibiotic which inhibits the formation of the bacterial cell wall.
|
-
- HY-N13958
-
-
- HY-125049
-
-
- HY-N13987
-
-
- HY-N13972
-
-
- HY-127142
-
-
- HY-B0992
-
-
- HY-A0256A
-
-
- HY-N13952
-
-
- HY-N13985
-
-
- HY-136968
-
-
- HY-B0915
-
|
CP-104354
|
Bacterial
Antibiotic
|
Infection
|
|
Orbifloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic which is approved for use in dogs.
|
-
- HY-N13969
-
-
- HY-W739930
-
|
|
Antibiotic
|
Infection
|
|
Desmethyl ofloxacin hydrochloride is a metabolite of the fluoroquinolone antibiotic Ofloxacin (HY-B0125).
|
-
- HY-N13983
-
-
- HY-B1824
-
-
- HY-N13956
-
-
- HY-169506
-
-
- HY-B0417A
-
-
- HY-N14182
-
-
- HY-106257S
-
|
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
|
Infection
|
|
Ceftolozane-d6 TFA is a deuterated labeled Ceftolozane TFA (HY-106257A). Ceftolozane TFA is a cephalosporin antibiotic that can be used to inhibit Gram-negative bacterial infections. Ceftolozane TFA can be used to synthesize new antibiotic that are more potent and safer .
|
-
- HY-121222R
-
|
|
PI3K
Apoptosis
|
Cancer
|
|
alpha-Bisabolol (Standard) is the analytical standard of alpha-Bisabolol. This product is intended for research and analytical applications. alpha-Bisabolol, an orally active sesquiterpene alcohol, induces cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol exerts a protective action against Cisplatin (HY-17394)-induced nephrotoxicity by mitigating inflammation and oxidative stress through the inhibition of NFκB activation. alpha-Bisabolol exhibits anti-inflammatory, analgesic, antibiotic and anticancer activities .
|
-
- HY-A0088S
-
|
Cefotaxim-d3 sodium; HR-756-d3 sodium
|
Isotope-Labeled Compounds
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Cefotaxime-d3 (sodium) is the deuterium labeled Cefotaxime (sodium salt). Cefotaxime sodium salt, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria[1][2][3][4][5].
|
-
- HY-B1166
-
-
- HY-B0108
-
-
- HY-114749
-
-
- HY-B0506
-
|
OPC7251
|
Bacterial
Antibiotic
|
Infection
|
|
Nadifloxacin (OPC7251) is a broad-spectrum fluoroquinolone antibiotic that is effective against acne vulgaris.
|
-
- HY-N14185
-
-
- HY-N14183
-
-
- HY-118983
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Pivampicillin hydrochloride is a penicillin antibiotic. Pivampicillin hydrochloride is a prodrug of Ampicillin (HY-B0522) .
|
-
- HY-N12908
-
|
Verrucarin H
|
Antibiotic
|
Infection
|
|
Roridin H (Verrucarin H) is an antibiotic and can be isolated from Myrothecium verrucaria .
|
-
- HY-131098
-
|
|
Antibiotic
|
Infection
|
|
Enduracidin A is a major component of Enduracidin. Enduracidin is a polypeptide antibiotic produced by Streptomyces fungicides .
|
-
- HY-N14937
-
-
- HY-N13871
-
-
- HY-122447
-
|
|
Antibiotic
|
Infection
|
|
Saroaspidin C (Compound 3) is an antibiotic that can be isolated from Sarothra japonica .
|
-
- HY-N7139A
-
|
Benzathine benzylpenicillin
|
Bacterial
Antibiotic
|
Infection
|
|
Penicillin G benzathine (Benzathine benzylpenicillin) is an antibiotic against many bacterial infections .
|
-
- HY-W008923
-
-
- HY-N14308
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aspiculamycin, a cytosine nucleoside, is an antibiotic. Aspiculamycin has a broad spectrum of antibacterial activity .
|
-
- HY-B0888
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfacetamide sodium monohydrate is a sulfonamide antibiotic, has been investigated for use in the treatment of pityriasis versicolor and rosacea.
|
-
- HY-122494A
-
-
- HY-119011
-
-
- HY-125723
-
-
- HY-119280
-
-
- HY-107027
-
|
|
Antibiotic
|
Infection
|
|
Polymyxin E2 sulfate is an antibiotic produced by the soil bacterium Bacillus polymyxa .
|
-
- HY-119759
-
|
|
Fungal
|
Infection
|
|
Lipoxamycin is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC50 of 21 nM .
|
-
- HY-14881A
-
|
R403323; TMC207 fumarate; R207910 fumarate
|
Bacterial
Antibiotic
|
Infection
|
|
Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
|
-
- HY-A0256B
-
-
- HY-P0092
-
-
- HY-N13890
-
-
- HY-10004
-
-
- HY-N12906
-
-
- HY-100496
-
|
4'-Fluoro-5'-O-sulfamoyladenosine; NSC 521007
|
Bacterial
|
Infection
|
|
Nucleocidin is an antitrypanosomal antibiotic, inhibiting the transfer of labeled amino acid from S-RNA to protein.
|
-
- HY-B1241
-
|
DHSM sulfate
|
Bacterial
Antibiotic
|
Infection
|
|
Dihydrostreptomycin sulfate is an aminoglycoside antibiotic, used to treat bacterial diseases in cattle, pigs and sheep.
|
-
- HY-116617R
-
|
|
Drug Metabolite
|
Others
|
|
Cefotaxime (Standard) is the analytical standard of Cefotaxime. This product is intended for research and analytical applications. Cefotaxime, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
|
-
- HY-A0088AR
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Cefotaxime (Standard) is the analytical standard of Cefotaxime. This product is intended for research and analytical applications. Cefotaxime, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
|
-
- HY-100436
-
|
ACT-179811
|
Bacterial
Antibiotic
|
Infection
|
|
Cadazolid (ACT-179811) is a new oxazolidinone antibiotic with potent activity against Clostridium difficile.
|
-
- HY-129285
-
-
- HY-B0810
-
|
FL-1039
|
Bacterial
Antibiotic
|
Infection
|
|
Pivmecillinam (FL-1039) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic.
|
-
- HY-N13883
-
-
- HY-122490
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Lincomycin (compound II) is a new polyether antibiotic that can be isolated from streptoverticillium olivoreticuli .
|
-
- HY-137927
-
|
|
Antibiotic
|
Others
|
|
Benapenem is a carbapenem-type agent that belongs to the broad-spectrum β-lactam antibiotic class.
|
-
- HY-N13887
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aerocyanidin is an antibiotic containing an isonitrile group, which is mainly effective against Gram-positive bacteria.
|
-
- HY-B0810A
-
|
FL-1039 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic.
|
-
- HY-131146
-
|
3-Amino-5-morpholinomethyl-2-oxazolidone
|
Antibiotic
|
Infection
|
|
AMOZ, a tissue bound metabolite of Furaltadone, Furaltadone is a synthetic nitrofuran antibiotic widely used
|
-
- HY-I0447
-
-
- HY-108988
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Albicidin is a peptide antibiotic with activity against various Gram-positive and Gram-negative microorganisms .
|
-
- HY-P1695
-
|
Ro 09-0198
|
Antibiotic
Bacterial
|
Infection
|
|
Cinnamycin (Ro 09-0198) is a tetracyclic peptide antibiotic that binds specifically to phosphatidylethanolamine (PE) .
|
-
- HY-22252
-
-
- HY-112639
-
-
- HY-131099
-
|
|
Antibiotic
|
Infection
|
|
Enduracidin B is a major component of Enduracidin. Enduracidin is a polypeptide antibiotic produced by Streptomyces fungicides .
|
-
- HY-N14187
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aspergillic acid is an antibiotic found in Aspergillus flavus. Aspergillic acid has a broad spectrum of antibacterial activity .
|
-
- HY-125070
-
|
|
Antibiotic
|
Infection
|
|
Racemomycin C is an analog of the antibiotic soramycin and is probably the 0-methyl derivative of racemomycin B.
|
-
- HY-N14014
-
-
- HY-N13019
-
|
|
Antibiotic
|
Infection
|
|
Elmycin D is an antibiotic, which can be isolated from Streptomyces cellulosae ssp. griseoincarnatus .
|
-
- HY-114658
-
-
- HY-127072
-
|
|
Antibiotic
|
Infection
|
|
Amicoumacin A is a antibiotic that can be isolated from the culture of Bacillus pumilus BN-103 .
|
-
- HY-119759A
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Lipoxamycin hemisulfate is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC50 of 21 nM .
|
-
- HY-N12223
-
-
- HY-118221
-
-
- HY-N7123
-
|
Sulphacetamide
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfacetamide (Sulphacetamide), a bacteriostatic sulphonamide, is a popular antibiotic prescribed for treating ocular infections .
|
-
- HY-B0408A
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Clindamycin (hydrochloride) is a semisynthetic lincosamide antibiotic, which inhibits protein synthesis by acting on the 50S ribosomal.
|
-
- HY-N13900
-
-
- HY-B0308
-
|
CI-978; AT-4140
|
Bacterial
Antibiotic
|
Infection
|
|
Sparfloxacin (CI-978) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity .
|
-
- HY-A0088R
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Cefotaxime (sodium) (Standard) is the analytical standard of Cefotaxime (sodium). This product is intended for research and analytical applications. Cefotaxime (Cefotaxim) sodium, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
|
-
- HY-112665R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Virginiamycin Complex (Standard) is the analytical standard of Virginiamycin Complex. This product is intended for research and analytical applications. Virginiamycin complex contains two streptogramin antibiotics, virginiamycin M1 and virginiamycin S1 produced by S. virginiae. As a complex, the two antibiotics act synergistically to irreversibly inhibit protein synthesis in bacteria .
|
-
- HY-118132
-
|
|
Antibiotic
|
Infection
|
|
LL-Z1220 is a novel antibiotic with the structure of 2-(3,8-dioxopentacyclo[5.1.0.0^~^~]oct-5-en-5-yl)-4H-pyran-4-one. This appears to be the first reported natural product containing a benzene dioxide group. This antibiotic readily undergoes valence isomerization to form 1,4-dioxopentacyclo. The chemical and spectroscopic properties of the antibiotic suggest that the benzene dioxide has a cis configuration.
|
-
- HY-W654101
-
|
Cefotaxim-d3; HR-756-d3
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
|
Infection
|
|
Cefotaxime-d3 is the deuterium labeled Cefotaxime (HY-A0088A). Cefotaxime is the β-lactamase stable cephalosporin and the third-generation cephalosporin antibiotic. Cefotaxime possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
|
-
- HY-W077634
-
|
AHBA
|
Drug Intermediate
|
Infection
|
|
3-Amino-5-hydroxybenzoic acid is a biosynthetic precursor of the mC7N unit of ansamycin antibiotics, including ansatrienin A and geldanamycin, as well as the antitumor antibiotic mitomycin C. 3-Amino-5-hydroxybenzoic acid may be an early intermediate in the shikimic acid pathway from glucose .
|
-
- HY-105846
-
|
|
DNA/RNA Synthesis
Bacterial
Antibiotic
|
Cancer
|
|
Nogalamycin is an anthracyclinone antibiotic. Nogalamycin is a potent antibiotic against Gram-positive bacteria, also has cytotoxicity against certain tumor cells. Nogalamycin is produced by Streptomyces nogalater var. Nogalater. Nogalamycin selectively inhibits RNA synthesis after binding to DNA template. Nogalamycin can be used for researching anticancer .
|
-
- HY-126783
-
|
11-Deoxycandicidin D
|
Antibiotic
|
|
|
Levorin A0 is a Levorin component. Levorin is an aromatic polyene (heptaene) antibiotic with high antifungal activity.
|
-
- HY-B1190
-
|
BL-S 578
|
Bacterial
Antibiotic
|
Infection
|
|
Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.
|
-
- HY-N13878
-
-
- HY-N7111
-
|
Sultamicillin (tosilate)
|
Bacterial
Antibiotic
|
Infection
|
|
Sultamicillin tosylate is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .
|
-
- HY-122505
-
-
- HY-106571
-
|
Ro 19-5248; T-2588
|
Bacterial
Antibiotic
|
Infection
|
|
Cefteram pivoxil (Ro 19-5248), an orally active cephalosporin antibiotic, is used for bacterial infections .
|
-
- HY-B2072A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cephaloridine hydrate is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity .
|
-
- HY-N6728
-
|
Fumigacin
|
Bacterial
Antibiotic
|
Infection
|
|
Helvolic acid (Fumigacin) is an antibiotic isolated from Xylaria sp, active against the Gram-positive bacteria .
|
-
- HY-121620
-
-
- HY-127007
-
|
|
Antibiotic
|
Infection
|
|
Okilactomycin is a lactone group antibiotic isolated from the culture filtrate of a strain of actinomycetes (Streptomyces species) .
|
-
- HY-N10585
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Malacidin B is a macrocyclic lipopeptide antibiotic that shows antibacterial activity in a calcium-dependent manner .
|
-
- HY-132915
-
|
|
Bacterial
|
Infection
|
|
Anti gram-positive/negative bacteria agent 1 is an antibiotic conjugate with an artificial MECAM-based siderophore.
|
-
- HY-B0330D
-
|
Dextrofloxacin
|
Bacterial
Antibiotic
|
Infection
|
|
(R)-Ofloxacin (Dextrofloxacin) is an antibiotic useful for the treatment of a number of bacterial infections . Antibacterial activity .
|
-
- HY-N10449
-
-
- HY-108874
-
|
Levorin; Vanobid; Candimon
|
Antibiotic
Fungal
Bacterial
|
Infection
|
|
Candicidin is a polyene antifungal antibiotic agent and can be isolated from Streptomyces griseus or Actinomyces levoris .
|
-
- HY-155364
-
-
- HY-N6670
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefotetan is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis .
|
-
- HY-Z7555
-
-
- HY-B0706
-
-
- HY-N7139B
-
|
Benzathine benzylpenicillin tetrahydrate
|
Antibiotic
Bacterial
|
Infection
|
|
Penicillin G benzathine tetrahydrate (Benzathine benzylpenicillin tetrahydrate) is an antibiotic against many bacterial infections .
|
-
- HY-131054
-
-
- HY-135394
-
|
|
Drug Metabolite
Antibiotic
|
Infection
|
|
3-Desacetyl Cefotaxime lactone is the active metabolite of Cefotaxime. Cefotaxime sodium salt is a third-generation cephalosporin antibiotic.
|
-
- HY-B2072
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cephaloridine is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity .
|
-
- HY-B0502
-
-
- HY-N7115
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sultamicillin is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .
|
-
- HY-B0706A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Flomoxef sodium is a oxacephem group antibiotic, with excellent activity against various Gram-positive bacteria .
|
-
- HY-B1075R
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Fosfomycin (calcium) (Standard) is the analytical standard of Fosfomycin (calcium). This product is intended for research and analytical applications. Fosfomycin (MK-0955) calcium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin calcium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-17624AR
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Framycetin (sulfate) (Standard) is the analytical standard of Framycetin (sulfate). This product is intended for research and analytical applications. Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin sulfate, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections .
|
-
- HY-B1907R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Rifamycin (sodium) (Standard) is the analytical standard of Rifamycin (sodium). This product is intended for research and analytical applications. Rifamycin sodium (Rifamycin SV monosodium) belongs to the family of ansamycin antibiotics and has been isolated from the fermentation of A. mediterranei or its mutants. Rifamycin sodium displays a broad spectrum of antibiotic activity against Gram-positive and, to a lesser extent, Gram-negative bacteria .
|
-
- HY-16752A
-
|
MK-7655 sodium
|
Beta-lactamase
Bacterial
|
Infection
|
|
Relebactam sodium (MK-7655 sodium) is a potent and selective β-lactamase inhibitor with the activity of delaying the development of bacterial resistance to antibiotics. Relebactam sodium can bind to a variety of β-lactamases, thereby improving the efficacy of β-lactam antibiotics. Relebactam sodium shows good application potential in inhibiting complicated bacterial infections .
|
-
- HY-B1434R
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
7-Aminocephalosporanic acid (Standard) is the analytical standard of 7-Aminocephalosporanic acid. This product is intended for research and analytical applications. 7-aminocephalosporanic acid (7-ACA) is a HSP90β inhibitor and an antibiotic. 7-Aminocephalosporanic acid is the core chemical structure of the synthesis of cephalosporin antibiotics and an effective β-lactamase inhibitor .
|
-
- HY-118043
-
|
|
Antibiotic
|
Infection
|
|
RK-1441B is an anti-phage antibiotic produced by Streptomyces sp. RK-1441 and belongs to the pyrrolo[1,4]benzodiazepine class. RK-1441B has antiphage activity but no significant antimicrobial activity against a supersusceptible E. coli strain to an antitumor antibiotic. RK-1441B is inactive in vitro and may be converted to the active form in the host organism. Its fellow antibiotic RK-1441A can form an adduct with guanine residues in the DNA chain to exert resistance .
|
-
- HY-112853
-
|
FR-31564
|
Bacterial
Antibiotic
|
Infection
|
|
Fosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial agent, which is active against both Gram-negative and Gram-positive bacteria.
|
-
- HY-118651
-
|
|
Bacterial
|
Infection
|
|
Griseoluteic acid, a phenazine antibiotic, is originally isolated from S. griseoluteus. Griseoluteic acid is a breakdown product of griseolutein A and B .
|
-
- HY-P2311
-
-
- HY-121473
-
-
- HY-B0474
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Tetracycline (hydrochloride) is a broad-spectrum antibiotic, exhibiting activity against a wide range of gram-positive and gram-negative bacteria.
|
-
- HY-17025
-
|
Ansamycin; LM-427
|
Bacterial
Antibiotic
|
Infection
|
|
Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.
|
-
- HY-123444
-
|
|
Antibiotic
|
Others
|
|
Kijimicin is a polyether antibiotic, and its specific mechanism of activity and application details are not described in detail from the existing information.
|
-
- HY-17565
-
|
Bleomycin sulfate
|
DNA/RNA Synthesis
Antibiotic
|
Cancer
|
|
Bleomycin sulfate is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin sulfate is an antitumor antibiotic .
|
-
- HY-A0253
-
|
Cephacetrile; Cephacetril
|
Bacterial
Antibiotic
|
Infection
|
|
Cefacetrile (Cephacetrile) is a broad-spectrum antibiotic that is effective in gram-positive and gram-negative bacterial infection .
|
-
- HY-123174
-
|
AY-24668
|
Antibiotic
Fungal
|
Infection
|
|
Demethoxyrapamycin (AY-24668) is a potent antifungal antibiotic which is co-produced with rapamycin by Streptomyces hygroscopicus .
|
-
- HY-136953
-
|
|
Antibiotic
|
Infection
|
|
LL-BM123γ1 is a potent broad spectrum glycocinnamoylspermidine antibiotic .
|
-
- HY-P5575
-
-
- HY-B0356AS
-
|
Bay-09867-dd8 hydrochloride hydrate
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Ciprofloxacin-d8 (hydrochloride hydrate) is the deuterium labeled Ciprofloxacin hydrochloride monohydrate. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
|
-
- HY-129669
-
|
|
Antibiotic
|
Infection
|
|
Landomycin A is a notable antibiotic belonging to the angucycline class, characterized by its hexasaccharide structure, and is derived from Streptomyces sp.
|
-
- HY-N11874
-
|
|
Bacterial
|
Infection
|
|
Staphyloferrin A is a siderophore protein that can be combined with antibiotics to study drug-resistant bacteria that cause skin diseases .
|
-
- HY-B0671S3
-
-
- HY-P5576
-
-
- HY-108879
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefotetan disodium is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis .
|
-
- HY-P2328
-
-
- HY-135577
-
|
|
Drug Metabolite
|
Infection
|
|
β-Apooxytetracycline is a degradation product of Oxytetracycline (HY-B0275). Oxytetracycline is a widespread antibiotic .
|
-
- HY-126606
-
|
|
Antibiotic
|
Infection
|
|
Isochlortetracycline is an inactive alkaline degradation product of the Chlortetracycline (HY-B1327A) (broad-spectrum antibiotic) .
|
-
- HY-131152
-
-
- HY-125546
-
|
|
Antibiotic
|
Infection
|
|
Erythromycin C is an antibiotic. Erythromycin C could be isolated from the fermentation process of the penicillium Streptomyces erythreus .
|
-
- HY-100997
-
|
A82846B; LY 264826; PA 45052A
|
Antibiotic
|
Infection
|
|
Chloroorienticin A (A82846B) is a glycopeptide antibiotic. Chloroorienticin A exhibits excellent activity against staphylococci and streptococci .
|
-
- HY-B0522
-
|
D-(-)-α-Aminobenzylpenicillin
|
Bacterial
Antibiotic
|
Infection
|
|
Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.
|
-
- HY-129728
-
-
- HY-B0356BS
-
|
Bay-09867-d8 hydrochloride monohydrate
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Ciprofloxacin-d8 (hydrochloride monohydrate) is the deuterium labeled Ciprofloxacin (hydrochloride monohydrate). Ciprofloxacin hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
|
-
- HY-17626B
-
|
WCK-2349 hydrochloride
|
Antibiotic
|
Infection
|
|
Alalevonadifloxacin (hydrochloride) (WCK-2349 (hydrochloride)) is a oraaly active anti-methicillin-resistant Staphylococcus aureus (MRSA) antibiotic .
|
-
- HY-121482
-
|
STA-21
|
STAT
|
Inflammation/Immunology
Cancer
|
|
(+)-Ochromycinone is a natural antibiotic that potently inhibits STAT3. (+)-Ochromycinone is used in the researches of cancers and psoriasis .
|
-
- HY-122207
-
|
|
Antibiotic
|
Infection
|
|
Erythromycin A enol ether is an acidic degradation product of Erythromycin A (macrolide antibiotic) and has no antibacterial effect .
|
-
- HY-125618
-
|
T-2636 D
|
Antibiotic
Bacterial
|
Infection
|
|
Lankacidinol A (T-2636 D) is an antibiotic, and shows antibacterial activity against Gram-positive bacteria .
|
-
- HY-10394R
-
|
PNU-100766 (Standard)
|
Bacterial
Antibiotic
|
Infection
|
|
Linezolid (Standard) is the analytical standard of Linezolid. This product is intended for research and analytical applications. Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics .
|
-
- HY-13725
-
-
- HY-B0671R
-
|
|
Bacterial
Autophagy
Antibiotic
|
Infection
Cancer
|
|
Vancomycin (Standard) is the analytical standard of Vancomycin. This product is intended for research and analytical applications. Vancomycin is an antibiotic for the treatment of bacterial infections.
|
-
- HY-B1275
-
|
Cefalotin sodium
|
Bacterial
Antibiotic
|
Infection
|
|
Cephalothin sodium is a first-generation cephalosporin antibiotic with broad antibacterial activity and is effective against Gram-positive and Gram-negative bacteria.
|
-
- HY-B1366
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Meclocycline Sulfosalicylate Salt is a tetracycline antibiotic with broad-spectrum antibacterial activities, preventing skin bacterial infections such as acne vulgaris .
|
-
- HY-125560
-
-
- HY-134518
-
|
Erythromycin A oxime; Erythromycin-9-oxime
|
Drug Intermediate
|
Infection
|
|
Erythromycin oxime is an intermediate of Azithromycin (HY-17506). Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
|
-
- HY-N14261
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Angiolam A is an antibiotic found in Angiococcus disciformis. Angiolam A exhibits notable antibacterial activity against Gram-positive bacteria .
|
-
- HY-101128
-
|
FR2054
|
Bacterial
Antibiotic
|
Infection
|
|
Bicyclomycin benzoate is an antibiotic exhibiting activity against a broad spectrum of Gram-negative bacteria and against the Gram-positive bacterium.
|
-
- HY-P5572
-
-
- HY-P10158
-
|
Porcine cathelicidin PMAP-36
|
Bacterial
|
Infection
|
|
PMAP-36 is an antimicrobial peptide, with sequence of GRFRRLRKKTRKRLKKIGKVLKWIPPIVGSIPLGCG. PMAP-36 with traditional antibiotics can enhance .
|
-
- HY-B0276S
-
|
2-ethylthioisonicotinamide-d3
|
Bacterial
Antibiotic
|
Infection
|
|
Ethionamide-d3 is the deuterium labeled Ethionamide. Ethionamide (2-ethylthioisonicotinamide) is an antibiotic used in the treatment of tuberculosis.
|
-
- HY-115367
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aldgamycin G is a macrolide antibiotic active against Gram-positive bacteria and can be isolated from Streptomyces avidinii .
|
-
- HY-N0195
-
|
2-Nitroimidazole
|
Bacterial
Antibiotic
|
Infection
|
|
Azomycin (2-Nitroimidazole) is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria.
|
-
- HY-107328
-
-
- HY-13725A
-
-
- HY-113569
-
|
L-Armentomycin
|
Antibiotic
Bacterial
|
Infection
|
|
Armentomycin (L-Armentomycin) is a nonprotein amino acid with antibiotic properties. Armentomycin mainly acts against Gram-negative bacteria .
|
-
- HY-N14910
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Actiketal is a glutarimide antibiotic that inhibits the incorporation of [ 3H]thymidine into EGF-stimulated Balb/MK cells .
|
-
- HY-126708
-
|
|
ADC Cytotoxin
Antibiotic
|
Infection
|
|
Luisol A, an aromatic tetraol, is a major metabolite of an estuarine marine actinomycete of the genus Streptomyces. Luisol A, is an anthraquinone antibiotic analog .
|
-
- HY-B0269S
-
|
DL 473-d9; Cyclopentylrifampicin-d9
|
Bacterial
Antibiotic
|
Infection
|
|
Rifapentine-d9 is the deuterium labeled Rifapentine. Rifapentine (DL 473) is an antibiotic compound used in the treatment of tuberculosis.
|
-
- HY-113735
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cephapirin Benzathine is the benzathine salt form of cephapirin. Cephapirin Benzathine is the first generation cephalosporin with broad spectrum antibiotic activity .
|
-
- HY-B2077
-
|
Tuberactinomycin N
|
Bacterial
Antibiotic
|
Infection
|
|
Enviomycin (Tuberactinomycin N) is a antibacterial antibiotic. Enviomycin has been used to research chronic cavitary pulmonary tuberculosis .
|
-
- HY-N13951
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Aranochlor A is an antibiotic found in Pseudoarachniotus roseus (HIL Y-30499). Aranochlor A exhibits antibacterial and antifungal activities .
|
-
- HY-121922
-
|
Dibromoverongiaquinol
|
Bacterial
|
Infection
|
|
Dienone B is a marine algicide with antibiotic activity against both Gram-positive and Gram-negative marine bacteria .
|
-
- HY-B1743S
-
-
- HY-A0269
-
|
Amdinocillin; FL 1060
|
Bacterial
Antibiotic
|
Infection
|
|
Mecillinam (Amdinocillin), the β-lactam antibiotic, has a broad spectrum of activity against gram-negative organisms .
|
-
- HY-107769
-
-
- HY-139628
-
|
|
Bacterial
|
Infection
Cancer
|
|
JPD447, a MAC-0547630 derivative, is a novel class of UppS inhibitor to potentiate β-lactam antibiotics.
|
-
- HY-W399439
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aurantiogliocladin is a weak antibiotic which was active against Staphylococcus epidermidis but not S. aureus. Aurantiogliocladin could inhibit biofilm formation .
|
-
- HY-121144
-
|
Refosporen
|
Bacterial
Antibiotic
|
Infection
|
|
Cefazedone (Refosporen), a first-generation cephalosporin, is a time-dependent antibiotic with activity against Gram-positive and Gram-negative bacteria .
|
-
- HY-B1244
-
|
1,2-Dimethyl-5-nitroimidazole
|
Parasite
Antibiotic
|
Infection
|
|
Dmetridazole (1,2-Dimethyl-5-nitroimidazole), a nitroimidazole-based antibiotic, combats protozoan infections .
|
-
- HY-129673
-
-
- HY-W739149
-
-
- HY-17442
-
|
Azaerythromycin A; Desmethyl Azithromycin
|
Bacterial
Antibiotic
|
Infection
|
|
Azathramycin (Azaerythromycin A) is an antibiotic that targets ribosomes and possesses antibacterial activity, which can be used in research related to infectious diseases .
|
-
- HY-N6784
-
-
- HY-109125A
-
|
SPA-S-753; SPA-S-752 L-aspartate
|
Antibiotic
Fungal
|
Infection
|
|
Amcipatricin diaspartate (SPA-S-753) is a semi-synthetic polyene antibiotic, with potent broad-spectrum antifungal activity .
|
-
- HY-129493
-
-
- HY-126813
-
|
|
Fungal
|
Infection
|
|
Concanamycin C inhibits proliferation of mouse splenic lymphocytes. Concanamycin C exhibits antibiotic effects against fungal and yeast .
|
-
- HY-N13892
-
-
- HY-N13884
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Amythiamicin D is a thiopeptide antibiotic that inhibits the growth of many Gram-positive bacteria, but not Gram-negative bacteria such as E.coli .
|
-
- HY-B0526
-
-
- HY-113560
-
-
- HY-122302
-
|
|
Antibiotic
|
Others
|
|
BU-2313 A is a compound with antimicrobial activity, whose structure was determined to be a dienoyltetraamide acid-containing antibiotic related to streptolysin and tilamycin.
|
-
- HY-111521
-
|
Carbavance
|
Antibiotic
Bacterial
|
Infection
|
|
Meropenem-vaborbactam is an antibiotic against nonfermenting Gram-negative clinical isolates, including Enterobacteriaceae isolates with resistant and carbapenemase genotypes .
|
-
- HY-Z8447
-
|
|
Drug Metabolite
|
Infection
|
|
(9E)-Erythromycin A oxime is a metabolite of Roxithromycin (HY-B0435). Roxithromycin is a semi-synthetic macrolide antibiotic.
|
-
- HY-B1244S
-
|
1,2-Dimethyl-5-nitroimidazole-d3
|
Parasite
Antibiotic
|
Infection
|
|
Dimetridazole-d3 is a deuterium labeled Dimetridazole. Dmetridazole, a nitroimidazole-based antibiotic, combats protozoan infections[1].
|
-
- HY-B1374
-
-
- HY-P5571
-
-
- HY-B0458AS
-
-
- HY-B0318S1
-
-
- HY-122334
-
|
|
Antibiotic
|
Infection
|
|
Myxopyronin A is an antibiotic that can be found in culture supernatant of the gliding bacterium Myxococcus fulvus strain Mx f50 (Myxobacterales) .
|
-
- HY-B0755
-
|
|
Antibiotic
|
Infection
|
|
Etimicin (sulfate), a fourth-generation aminoglycoside antibiotic, is now widely clinically used due to its high efficacy and low toxicity.
|
-
- HY-129291
-
|
AM 6201
|
Antibiotic
Bacterial
Fungal
|
Infection
Cancer
|
|
Reductiomycin is an antibiotic, which exhibits antimicrobial activity against gram positive bacteria and fungi. Reductiomycin exhibits antitumor activity .
|
-
- HY-W055872
-
|
|
Antibiotic
|
Infection
|
|
Erythromycylamine is a macrolide antibiotic. Erythromycylamine has antibacterial activity against most Gram-positive cocci and M. catarrhalis .
|
-
- HY-120185
-
|
UCT-1003
|
Topoisomerase
|
Infection
Cancer
|
|
Saintopin is an antitumor antibiotic. Saintopin is also an inhibitor of DNA topoisomerases I and II. Saintopin induces DNA cleavage .
|
-
- HY-151567
-
|
|
Bacterial
|
Infection
|
|
Antibacterial agent 123 (compound 111) is a potent membrane-disrupting agent to combat antibiotic-resistant Gram-positive bacteria .
|
-
- HY-137064
-
|
|
iGluR
|
Neurological Disease
|
|
Memantine lactose adduct is a lactose adduct of Memantine (HY-B0591) and an intermediate in the synthesis of adamantane amine antibiotics .
|
-
- HY-117074
-
-
- HY-N7218
-
-
- HY-131557
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
O-Deacetylravidomycin, a microbial metabolite discovered in Streptomyces, is an antibiotic. O-Deacetylravidomycin exhibits light-dependent antibacterial and anticancer activities .
|
-
- HY-10394S1
-
|
PNU-100766-d8
|
Antibiotic
Bacterial
Isotope-Labeled Compounds
|
Infection
|
|
PNU-100766-d8 is deuterated labeled Linezolid (HY-10394). Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics .
|
-
- HY-A0279
-
|
Pristinamycine
|
Bacterial
Antibiotic
|
Infection
|
|
Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF) .
|
-
- HY-149333
-
|
|
Bacterial
|
Infection
|
|
BO-1 is a benzoate ester with antibacterial activity. BO-1 inhibits multidrug-resistant Staphylococcus aureus, and acts function synergistically with antibiotic, such as Ciprofloxacin (HY-B0356). BO-1 can reverse the resistance of antibiotic-resistant S. aureus strains, and decreases the level of inflammatory factors IL-6 and C-reactive protein in vivo in mice .
|
-
- HY-101411R
-
|
|
GABA Receptor
Endogenous Metabolite
Bacterial
|
Others
|
|
Josamycin propionate (Standard) is the analytical standard of Josamycin propionate. This product is intended for research and analytical applications. Josamycin propionate is classified as a macrolide antibiotic.
|
-
- HY-139106
-
|
|
Antibiotic
|
Others
|
|
N-Demethylansamitocin P-3 can be prepared from Ansamitocin (an antitumor ansamycin antibiotic) by Streptomyces minutiscleroticus IFO 13361 .
|
-
- HY-N13905
-
-
- HY-125561R
-
|
|
Antibiotic
|
Others
|
|
Josamycin propionate (Standard) is the analytical standard of Josamycin propionate. This product is intended for research and analytical applications. Josamycin propionate is classified as a macrolide antibiotic.
|
-
- HY-105165A
-
|
BBR 3438
|
Antibiotic
|
Cancer
|
|
Nortopixantrone dihydrochloride (BBR 3438) is a 9-aza-anthrapyrazole-based antineoplastic antibiotic. Nortopixantrone dihydrochloride plays an important role in cacner research .
|
-
- HY-B0026
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Ceftiofur hydrochloride is a semisynthetic antibiotic, with activity against various gram-positive and gram-negative, aerobic and anaerobic bacteria encountered by domestic animals .
|
-
- HY-100180
-
|
LCB01-0371
|
Bacterial
Antibiotic
|
Infection
|
|
Delpazolid is a novel oxazolidinone antibiotic agent which can inhibit the growth of MSSA and MRSA with a MIC90 of 2 μg/mL for both of them.
|
-
- HY-142124
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Kalimantacin A is a potent antibiotic. Kalimantacin A shows antibacterial activity against staphylococcus including methicillin-resistant staphylococcus aureus (MRSA) .
|
-
- HY-N7242
-
|
|
Antibiotic
|
Infection
|
|
Plicacetin is a crystalline antibiotic isolated from the fermentation broth of Streptomyces actinomycetes and is structurally similar to Amicetin (HY-120383) and Bamicetin. .
|
-
- HY-130995
-
|
|
Antibiotic
ADC Cytotoxin
|
Infection
|
|
Agrochelin, an alkaloid cytotoxic antibiotic, is produced by the fermentation of a marine Agrobacterium sp. Agrochelin has cytotoxic activity in tumor cell lines .
|
-
- HY-N7102
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive and gram-negative, aerobic and anaerobic bacteria encountered by domestic animals .
|
-
- HY-B1743AS
-
|
CL13900-d3 dihydrochloride
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Puromycin-d3 (dihydrochloride) is the deuterium labeled Puromycin dihydrochloride. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis[1].
|
-
- HY-N14301
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Aquayamycin is an angucycline antibiotic. Aquayamycin is active against Gram-positive bacteria, Ehrlich ascites carcinoma, and Yoshida rat sarcoma cells .
|
-
- HY-124138
-
|
Albomycetin; Amaromycin
|
Antibiotic
Bacterial
|
Infection
|
|
Pikromycin is a macrolide antibiotic that has been found in S. venezuelae and active against E. coli, S. aureus and B. subtilis .
|
-
- HY-A0071R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tildipirosin (Standard) is the analytical standard of Tildipirosin. This product is intended for research and analytical applications. Tildipirosin, a long-acting macrolide, has antibiotic activity.
|
-
- HY-B0356S
-
|
Bay-09867-d8 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Ciprofloxacin-d8 (hydrochloride) is the deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
|
-
- HY-108881
-
-
- HY-18258
-
-
- HY-B0343BS
-
|
A-56620-d8 hydrochloride trihydrate
|
Bacterial
|
Inflammation/Immunology
|
|
Sarafloxacin-d8 (hydrochloride trihydrate) is the deuterium labeled Sarafloxacin hydrochloride trihydrate. Sarafloxacin hydrochloride trihydrate is a quinolone antibiotic compound[1][2].
|
-
- HY-B2094
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Arbekacin, an aminoglycoside antibiotic, exhibits broad antimicrobial activities against not only Gram-positive bacteria but also Gram-negative bacteria .
|
-
- HY-121004
-
|
Lycopersin
|
Fungal
Antibiotic
|
Infection
|
|
Bikaverin (Lycopersin) is a reddish pigment produced by different fungal species. Bikaverin shows antibiotic properties against certain protozoa and fungi .
|
-
- HY-B0322
-
|
Ro 4-2130
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Sulfamethoxazole (Ro 4-2130) is a sulfonamide bacteriostatic antibiotic, used for bacterial infections. Sulfonamides is a competitive antagonists of para-aminobenzoic acid (PABA) .
|
-
- HY-124035
-
|
SF2583A
|
Antibiotic
Parasite
|
Infection
|
|
Streptochlorin (SF2583A) is an antibiotic. Streptochlorin has antitrypanosomal activity with an IC50 value of 230 ng/ml for GUTat 3.1 .
|
-
- HY-A0076
-
|
LJC 11036
|
Bacterial
Antibiotic
|
Infection
|
|
Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa.
|
-
- HY-B0356S1
-
|
Bay-09867-d8
|
Bacterial
Antibiotic
|
Infection
|
|
Ciprofloxacin-d8 is the deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
|
-
- HY-B0239S
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Chloramphenicol-d5 is the deuterium labeled Chloramphenicol. Chloramphenicol is a broad-spectrum antibiotic against bacterial infections[1][2].
|
-
- HY-N5197
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Dapdiamide A is an antibiotic found in Pantoea agglomerans CU0119 strain, exhibiting antibacterial activity and potential applications in anti-infective research .
|
-
- HY-B0343AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sarafloxacin (hydrochloride) (Standard) is the analytical standard of Sarafloxacin (hydrochloride). This product is intended for research and analytical applications. Sarafloxacin (hydrochloride) (A-56620 (hydrochloride)) is a quinolone antibiotic agent.
|
-
- HY-B1275A
-
-
- HY-N8492
-
|
|
Antibiotic
|
Infection
|
|
Monascorubrin is purified from the mycelium of Monascus purpureus. Monascorubrin has significant antibiotic activities against Bacillus subtilis and Candida pseudotropicalis .
|
-
- HY-13588
-
|
SCE-129 sodium
|
Bacterial
Antibiotic
|
Infection
|
|
Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC50 value of 16 μM .
|
-
- HY-13588B
-
|
SCE-129 sodium hydrate
|
Antibiotic
Bacterial
|
Infection
|
|
Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC50 value of 16 μM .
|
-
- HY-117869
-
-
- HY-B1592
-
|
|
Bacterial
|
Infection
|
|
Carbomycin is a peptidyl transferase inhibitor with an inhibition rate of 95% at 200 μM .
|
-
- HY-120658
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
(Rac)-LY193239 is a racemic modification of LY193239 (HY-120658A). LY193239 is a higher-lactam pyrazolidinone antibacterial agent .
|
-
- HY-18999R
-
|
|
Antibiotic
|
Infection
|
|
4-epi-Chlortetracycline (hydrochloride) (Standard) is the analytical standard of 4-epi-Chlortetracycline (hydrochloride). This product is intended for research and analytical applications. 4-epi-Chlortetracycline hydrochloride is an epimetabolite of Chlortetracycline hydrochloride. Chlortetracycline hydrochloride is an orally active, potent and selective inhibitor of methanogenic bacteria with bactericidal effect .
|
-
- HY-127019R
-
-
- HY-157027
-
|
|
Fungal
|
Others
|
|
Antifungal agent 85 (compound 24f) is a potent antibacterial compound with the minimum inhibitory concentration (MIC) values between 2.5 and 10 μM against various Gram-positive bacteria .
|
-
- HY-18999
-
|
|
Antibiotic
|
Infection
|
|
4-epi-Chlortetracycline hydrochloride is an epimetabolite of Chlortetracycline hydrochloride. Chlortetracycline hydrochloride is an orally active, potent and selective inhibitor of methanogenic bacteria with bactericidal effect .
|
-
- HY-B1174
-
|
Kanamycin B
|
Antibiotic
Bacterial
|
Infection
|
|
Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .
|
-
- HY-N7120
-
|
PGP hydrate
|
Bacterial
Antibiotic
|
Infection
|
|
Penicillin G Procaine hydrate (PGP hydrate), a β-lactam antibiotic, is a crystalline complex produced by chemically combining penicillin G with procaine .
|
-
- HY-N8401
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Musellactone is a lactone that can be isolated from Musella lasiocarpa. Musellactone is an antibiotic, that exhibits antibacterial activity against Bacillus megaterium and Sarcina lutea .
|
-
- HY-148209
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Balhimycin is a glycopeptide antibiotic, found from the fermentation broth of a Amycolatopsis sp. Balhimycin shows anti-bacterial activity against staphylococci and anaerobes .
|
-
- HY-B0898R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Ceftiofur (sodium) (Standard) is the analytical standard of Ceftiofur (sodium). This product is intended for research and analytical applications. Ceftiofurna sodium is a third-generation cephalosporin antibiotic approved for veterinary use.
|
-
- HY-N10081
-
-
- HY-B0925S
-
-
- HY-N6708
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Alamethicin, isolated from Trichoderma viride, is a channel-forming peptide antibiotic and induces voltage-gated conductance in model and cell membranes .
|
-
- HY-B0522A
-
|
D-(-)-α-Aminobenzylpenicillin sodium salt
|
Bacterial
Antibiotic
|
Infection
|
|
Ampicillin sodium (D-(-)-α-Aminobenzylpenicillin sodium salt) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .
|
-
- HY-N7141R
-
|
|
Parasite
Antibiotic
Bacterial
|
Infection
|
|
Spiramycin I (Standard) is the analytical standard of Spiramycin I. This product is intended for research and analytical applications. Spiramycin I is a macrolide antibiotic and antiparasitic .
|
-
- HY-17506R
-
|
|
Bacterial
Autophagy
Antibiotic
Parasite
|
Infection
Cancer
|
|
Azithromycin (Standard) is the analytical standard of Azithromycin. This product is intended for research and analytical applications. Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
|
-
- HY-B0269R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Rifapentine (Standard) is the analytical standard of Rifapentine. This product is intended for research and analytical applications. Rifapentine (DL 473) is an antibiotic used in tuberculosis research .
|
-
- HY-136434
-
|
m-threo-Chloramphenicol
|
Antibiotic
|
Others
|
|
m-Chloramphenicol (m-threo-Chloramphenicol) is an impurity of Chloramphenicol. Chloramphenicol, a broad-spectrum antibiotic, acts as a potent inhibitor of bacterial protein biosynthesis .
|
-
- HY-Z9100
-
|
|
Antibiotic
|
Infection
|
|
N-demethyl Promethazine hydrochloride is a metabolite of Phenothiazine (HY-Y0055). Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities.
|
-
- HY-N7097
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sulbenicillin disodium is the disodium salt of Sulbenicillin. Sulbenicillin is a Penicillin antibiotic with antibacterial activity against a number of mucoid and non-mucoid strains of Pseudomonas aeruginosa .
|
-
- HY-A0110A
-
|
CTM-HE hydrochloride; SCE-2174 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Cefotiam hexetil hydrochloride (CTM-HE) is an oral third-generation cephalosporin, which is a proagent of cefotiam, but has no anti-bacterial property. Cefotiam is an antibiotic .
|
-
- HY-Y0055
-
-
- HY-N14665
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Atrovenetin is an antibiotic found in Penicillium species. Atrovenetin has inhibitory activity against Bacillus subtilis and Staphylococcus aureus. Atrovenetin is also a potent antioxidant.
|
-
- HY-113795
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aldgamycin E is a neutral macrolide antibiotic that can be derived from culture filtrates of Streptomyces lavendulae. Aldgamycin E has antibacterial activity .
|
-
- HY-156074
-
|
|
Antibiotic
|
Infection
|
|
Erythromycin propionate is an antibiotic that may have some hepatotoxic properties. Erythromycin propionate has no significant side effects below 0.5 mM .
|
-
- HY-B0435R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Roxithromycin (Standard) is the analytical standard of Roxithromycin. This product is intended for research and analytical applications. Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.
|
-
- HY-P2123A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Colistin A sulfate hydrate is a major component of Colistin. Colistin is a polymyxin antibiotic and can be used to combat infections caused by problematic gram-negative bacteria .
|
-
- HY-N13885
-
|
|
Antibiotic
Bacterial
Parasite
|
Infection
|
|
Amythiamicin A is an antimicrobial antibiotic against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum .
|
-
- HY-B0467AS
-
-
- HY-B0458R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefprozil (monohydrate) (Standard) is the analytical standard of Cefprozil (monohydrate). This product is intended for research and analytical applications. Cefprozil monohydrate (Cefzil) is a second-generation cephalosporin type antibiotic .
|
-
- HY-B1436
-
|
|
STAT
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Nifuroxazide is an effective inhibitor of STAT3, also exerts potent anti-tumor and anti-metastasis activity. Nifuroxazide is an orally active nitrofuran antibiotic.
|
-
- HY-B0467S
-
-
- HY-B1252B
-
-
- HY-128916
-
|
|
Bacterial
|
Infection
|
|
dmDNA31 is a rifamycin-class antibiotic that inhibits bacterial DNA-dependent RNA polymerase with potent bactericidal activity against S. aureus .
|
-
- HY-16472
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sulfacytine is a short-acting sulfonamide antibiotic. Sulfacytine is active against bacteria and is an effective agent for the research of acute uncomplicated urinary tract infections .
|
-
- HY-151224R
-
|
|
DNA/RNA Synthesis
|
Others
|
|
Roxithromycin (Standard) is the analytical standard of Roxithromycin. This product is intended for research and analytical applications. Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.
|
-
- HY-18257
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Rolitetracycline, a derivative of tetracycline, is a broad-spectrum antibiotic . Rolitetracyclin has a role as a protein synthesis inhibitor, an antiprotozoal agent and a proagent .
|
-
- HY-U00035
-
|
|
Bacterial
|
Infection
|
|
MGB-BP-3 is an antibiotic that has been shown to be active against a broad range of important multi-resistant Gram-positive pathogens.
|
-
- HY-N11415
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aurachin SS is a nature product that could be isolated from Streptomyces sp. NA04227. Aurachin SS is an antibiotic and has antibacterial activity .
|
-
- HY-17506AR
-
|
|
Bacterial
Autophagy
Antibiotic
Parasite
|
Infection
Cancer
|
|
Azithromycin (hydrate) (Standard) is the analytical standard of Azithromycin (hydrate). This product is intended for research and analytical applications. Azithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
|
-
- HY-138194
-
|
A-16316-C
|
Antibiotic
Fungal
|
Infection
|
|
Destomycin B (A-16316-C) is an antibiotic, and is active against fungi. Destomycin B also has anthelmintic activity .
|
-
- HY-14603
-
|
Iodochlorohydroxyquinoline
|
Fungal
Autophagy
Mitophagy
Antibiotic
Parasite
|
Infection
Cancer
|
|
Clioquinol (Iodochlorhydroxyquin) is a topical antifungal agent with anticancer activity. Clioquinol acts as an oral antimicrobial agent for the research of diarrhea and skin infections. Antibiotic .
|
-
- HY-A0089
-
|
Polymyxin E sulfate
|
Bacterial
Autophagy
Antibiotic
|
Infection
|
|
Colistin sulfate is a polypeptide antibiotic which inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria.
|
-
- HY-13766A
-
|
VX-853-2
|
Bacterial
|
Others
|
|
Timcodar mesylate (VX-853-2) and its analog VX-710 are mammalian multidrug-resistant bacterial efflux pump inhibitors that directly inhibit ethidium bromide efflux in Staphylococcus aureus. Timcodar mesylate has the potential to enhance antibiotic activity by inhibiting bacterial efflux pumps, effectively reducing the minimum inhibitory concentration of some antibiotics against Gram-positive pathogens such as Staphylococcus aureus, Enterococcus and Streptococcus pneumoniae .
|
-
- HY-121136A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Chartreusin sodium is an antibiotic that is active against certain Gram-positive organisms and mycobacteria. Chartreusin is also active against the Micrococcus fiyogenes v. aureus phage .
|
-
- HY-B1894
-
|
Ro 15-8075 free base
|
Bacterial
Antibiotic
|
Infection
|
|
Cefetamet pivoxyl is a cephalosporin antibiotic. Cefetamet pivoxyl inhibits 355 enteropathogens Keime, Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila .
|
-
- HY-B1340
-
-
- HY-B0272
-
-
- HY-118021
-
|
YL-0358M-A
|
Antibiotic
|
Infection
|
|
Hatomamicin is an alkaloid antibiotic that can be isolated from the culture filtrate of Sucrose Polyspora. Hatomamicin exhibits antibacterial activity against Gram-positive bacteria .
|
-
- HY-B0276R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Ethionamide (Standard) is the analytical standard of Ethionamide. This product is intended for research and analytical applications. Ethionamide (2-ethylthioisonicotinamide) is a second-line anti-tuberculosis antibiotic.
|
-
- HY-125608
-
|
Lipiarmycin B3
|
Antibiotic
Bacterial
|
Infection
|
|
Tiacumicin C (Lipiarmycin B3) is an antibiotic with activity against Gram-positive bacteria. Tiacumicin C is employed in research related to bacterial infections .
|
-
- HY-B1086
-
|
N-Acetyl-DL-phenylalanine
|
Endogenous Metabolite
|
Neurological Disease
|
|
Afalanine (N-Acetyl-DL-phenylalanine) is an endogenous metabolite of an endophytic fungus with antidepressant activity. Afalanine can be used in combination with antibiotics to prevent renal damage.
|
-
- HY-B1463R
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Penicillin G sodium salt (Standard) is the analytical standard of Penicillin G sodium salt. This product is intended for research and analytical applications. Penicillin G sodium salt is a typical β-lactam antibiotic.
|
-
- HY-128459R
-
|
|
Drug Metabolite
|
Others
|
|
N-Demethylerythromycin A (Standard) is the analytical standard of N-Demethylerythromycin A. This product is intended for research and analytical applications. N-Demethylerythromycin A is a metabolite of Erythromycin A. Erythromycin A is an antibiotic .
|
-
- HY-N13906
-
-
- HY-B0875B
-
|
SCE-1365 sodium
|
Antibiotic
Bacterial
|
Infection
|
|
Cefmenoxime sodium is a new semisynthetic cephalosporin antibiotic. Cefmenoxime sodium has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .
|
-
- HY-P1720
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Telomycin is a calcium-dependent antibiotic, which can be produced by Streptomyces. Telomycin inhibits gram-positive bacteria, including multidrug-resistant (MDR) pathogens .
|
-
- HY-125388
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Martinomycin is an antibiotic, which inhibits Staphylococcus spp., Streptococcus spp. and Enterococcus spp., with MICs ranging from 0.06 to 0.5 μg/mL .
|
-
- HY-135212
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .
|
-
- HY-B1743AR
-
|
|
Bacterial
Antibiotic
Parasite
|
Infection
|
|
Puromycin (dihydrochloride) (Standard) is the analytical standard of Puromycin (dihydrochloride). This product is intended for research and analytical applications. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis .
|
-
- HY-B0522B
-
|
D-(-)-α-Aminobenzylpenicillin trihydrate
|
Bacterial
Antibiotic
|
Infection
|
|
Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.
|
-
- HY-N10617
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Hygromycin A is a Borrelia burgdorferi-selective antibiotic. Hygromycin A is a spirochete-specific antibacterial that is conducive to gut health. Hygromycin A can be used for Lyme disease research .
|
-
- HY-108279
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Ulifloxacin is a broad-spectrum quinolone antibiotic. Ulifloxacin is the active metabolite of Prulifloxacin (HY-B0024). Ulifloxacin has anti-bacterial activity .
|
-
- HY-105165
-
|
BBR 3438 free base
|
Antibiotic
|
Cancer
|
|
Nortopixantrone (BBR 3438 free base) is a 9-aza-anthrapyrazole-based antineoplastic antibiotic. Nortopixantrone plays an important role in cacner research .
|
-
- HY-P0274
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
PGLa, a 21-residue peptide, is an antimicrobial peptide. PGLa is a member of the magainin family of antibiotic peptides found in frog skin and its secretions .
|
-
- HY-N13881
-
|
|
Antibiotic
Bacterial
Parasite
|
Infection
|
|
Amythiamicin C is an antimicrobial antibiotic against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum .
|
-
- HY-121136
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Chartreusin is an antibiotic that is active against certain Gram-positive organisms and mycobacteria. Chartreusin is also active against the Micrococcus fiyogenes v. aureus phage .
|
-
- HY-B0472R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Streptomycin (sulfate) (Standard) is the analytical standard of Streptomycin (sulfate). This product is intended for research and analytical applications. Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.
|
-
- HY-W129471R
-
|
|
Bacterial
|
Others
|
|
Streptomycin (sulfate) (Standard) is the analytical standard of Streptomycin (sulfate). This product is intended for research and analytical applications. Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.
|
-
- HY-W076898A
-
|
|
Antibiotic
|
Others
|
|
Hydroxyethyl disulfide blocks the inhibitory effect of showdomycin on methotrexate-resistant thymidylate synthase and is also protected by its substrate deoxyuridylic acid, preventing inactivation of the antibiotic .
|
-
- HY-N7123S1
-
-
- HY-126818
-
|
|
Bacterial
|
Infection
|
|
Desfuroylceftiofur is an active metabolite of Ceftiofur which is a broad-spectrum cephalosporin antibiotic. Desfuroylceftiofur is active against gram-positive and gram-negative bacteria .
|
-
- HY-N7123S
-
|
Sulphacetamide-d4
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Sulfacetamide-d4 is the deuterium labeled Sulfacetamide. Sulfacetamide (Sulphacetamide), a bacteriostatic sulphonamide, is a popular antibiotic prescribed for treating ocular infections[1][2].
|
-
- HY-B0337R
-
|
Sulphadimethoxine (Standard)
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfadimethoxine (Standard) is the analytical standard of Sulfadimethoxine. This product is intended for research and analytical applications. Sulfadimethoxine (Sulphadimethoxine) is a sulfonamide antibiotic used to treat many infections .
|
-
- HY-126740
-
|
|
Antibiotic
Fungal
|
Infection
Cancer
|
|
Anguinomycin A is an antibiotic that exhibits good inhibitory activity against G. boninense with an MIC value of 5 µg/disk. Anguinomycin A has antitumor activity .
|
-
- HY-125512
-
|
|
Antibiotic
|
Infection
|
|
Saccharocarcin B is a macrocyclic lactone antibiotic that is active against the Gram-positive bacteria M. luteus and S. aureus as well as the Gram-negative bacteria C. trachomatis.
|
-
- HY-129166
-
|
|
Bacterial
|
Infection
|
|
UCM53, a FtsZ inhibitor, is an antibacterial agent. UCM53 can inhibit the growth of clinical isolates of antibiotic-resistant Staphylococcus aureus and Enterococcus faecalis
|
-
- HY-117260
-
-
- HY-N10338
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Mildiomycin is a Streptoverticillium rimofaciens antibiotic against powdery mildew of barley. Mildiomycin inhibits some Mycobacterium and Rhodotorula growth, but fails against most fungi and bacteria .
|
-
- HY-B1190S
-
|
BL-S 578-d4 hydrate
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Cefadroxil-d4 (hydrate) is the deuterium labeled Cefadroxil. Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.
|
-
- HY-B1369AS
-
|
N-Formimidoyl thienamycin-d4; MK0787-d4
|
Isotope-Labeled Compounds
|
Infection
|
|
Imipenem-d4 (N-Formimidoyl thienamycin-d4) is a deuterium labeled Imipenem (HY-B1369A). Imipenem is an antibiotic .
|
-
- HY-N15184
-
|
Pradimicin C
|
Bacterial
Fungal
|
Infection
|
|
Benanomicin B (Pradimicin C) is an antifungal antibiotic that also has antibacterial activity against two Gram-positive bacteria: Micrococcus luteus and Corynebacterium bovis .
|
-
- HY-B0502S
-
-
- HY-131144S
-
|
|
Antibiotic
|
Infection
|
|
AMOZ-d5 is a deuterium labeled AMOZ. AMOZ, a tissue bound metabolite of Furaltadone, Furaltadone is a synthetic nitrofuran antibiotic widely used[1].
|
-
- HY-107833
-
|
|
Bacterial
|
Infection
|
|
A40926, the precursor of Dalbavancin, is a second-generation glycopeptide antibiotic. A40926 inhibits gram-positive bacteria, and is very active against Neisseria gonorrhoeae .
|
-
- HY-117180
-
|
30-Hydroxy-naphthomycin C
|
Antibiotic
|
Infection
Cancer
|
|
Diastovaricin I (30-Hydroxy-naphthomycin C) is an antibiotic without exhibiting antimicrobial activity. Diastovaricin I induces differentation of mouse Friend cell .
|
-
- HY-119657
-
|
|
Bacterial
|
Others
|
|
Cellocidin is an agricultural antibiotic with preventive effects against rice bacterial leaf blight and is thought to work by inhibiting the α-ketoglutarate-succinate system in Xanthomonas sp.
|
-
- HY-B0132A
-
|
MK-0366 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Norfloxacin hydrochloride (MK-0366 hydrochloride) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.
|
-
- HY-B0337S2
-
-
- HY-119589
-
|
Dactylarin
|
Antibiotic
|
Others
|
|
Altersolanol B (Dactylarin), a compound isolated from fungi, is structurally related to antibiotics and has been shown to induce ATP catabolism in Ehrlich ascites tumor cells.
|
-
- HY-P10233
-
|
|
Bacterial
|
Infection
|
|
SAAP 148 is an antimicrobial and antibiofilm agent, and exhibits inhibitory efficacy against antibiotic-resistant pathogens, with LC50 of 0.8-12.8 μM .
|
-
- HY-B0465R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Oxacillin (sodium monohydrate) (Standard) is the analytical standard of Oxacillin (sodium monohydrate). This product is intended for research and analytical applications. Oxacillin sodium monohydrate is an antibiotic similar to Flucloxacillin used in resistant staphylococci infections study .
|
-
- HY-111525
-
|
|
Oxidative Phosphorylation
Bacterial
Antibiotic
|
Infection
|
|
Monactin is a mactrotetralide antibiotic and a non-selective ionophore for monovalent cations, including potassium, sodium, and lithium. Monactin is isolated from Streptomyces and has antiproliferative activity .
|
-
- HY-17626C
-
|
(R)-WCK-2349
|
Antibiotic
|
Others
|
|
(R)-Alalevonadifloxacin mesylate is an isomer of Alalevonadifloxacin mesylate (HY-17626B). Alalevonadifloxacin mesylate is a oraly active anti-methicillin-resistant Staphylococcus aureus (MRSA) antibiotic .
|
-
- HY-148286
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Gentamicin C1a is the precursor of the semi-synthetic antibiotic Etimicin, and has antibacterial activity. Gentamicin C1a is the major component of the Gentamicin complex .
|
-
- HY-B0132
-
-
- HY-17577
-
-
- HY-158977
-
|
|
Beta-lactamase
Bacterial
|
Infection
|
|
β-Lactamase-IN-9 (compound 2) is a β-lactamase inhibitor that can restore the sensitivity of pathogens to β-lactam antibiotics .
|
-
- HY-B0308S
-
-
- HY-N13919
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Avilamycin B is an orally active antibiotic that can be isolated from Streptomyces viridochomogenes. Avilamycin B can be used for the research of intestinal bacteria-related diseases .
|
-
- HY-W706112
-
-
- HY-106922A
-
|
GV104326 sodium
|
Antibiotic
Bacterial
|
Infection
|
|
Sanfetrinem (GV104326) sodium is a beta-lactamase-stable antibiotic. Sanfetrinem sodium has broad-spectrum activity against gram-positive and gram-negative bacteria .
|
-
- HY-16158
-
|
Wy-4508; Aminocyclohexylpenicillin; Ciclacillin
|
Bacterial
Antibiotic
|
Infection
|
|
Cyclacillin (Wy-4508) is an orally active aminopenicillin antibiotic, shows antibacterial activity against a wide range of gram-positive and gram-negative pathogens .
|
-
- HY-126140
-
|
|
Bacterial
|
Infection
|
|
MDRTB-IN-1 (5aα) is an antibiotic which is against Mycobacterium tuberculosis H37Rv with a MIC90 value of 10.5 μM .
|
-
- HY-136456
-
|
|
Drug Metabolite
|
Others
|
|
2-NP-AMOZ is a 2-nitrophenyl derivative of AMOZ (a metabolite of antibiotic Furaltadone), can be used to detect protein bound AMOZ .
|
-
- HY-136991
-
|
|
Antibiotic
|
Others
|
|
Basacv is a DNA-polyintercalating bifunctional compound with DNA-high affinity. Basacv is structurally analogous to the antibiotic anti-tumour drug Triostin A and act as a bis-intercalator .
|
-
- HY-N13877
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Arugomycin, an anthracycline natural product, is antibiotic against Gram-positive bacteria. Arugomycin has potential as an antitumor agent from its ability to intercalate DNA .
|
-
- HY-P5570
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aurein 2.3 is an antibiotic antimicrobial peptide. Aurein 2.3 partially inhibits E.coli ATPase activity and inhibits cell growth .
|
-
- HY-B0198S
-
-
- HY-N15095
-
|
|
Antibiotic
Bacterial
Parasite
|
Infection
|
|
Aplasmomycin is a boron-containing macrodiolide antibiotic. Aplasmomycin shows antimicrobial activity against Gram-positive bacteria and exhibits inhibitory activity against plasmodium infections in vivo .
|
-
- HY-121349
-
|
|
Bacterial
Fungal
Antibiotic
|
Infection
Cancer
|
|
Aerothionin is an antibiotic with potent antimicrobial efficacy against bacteria and fungi. Aerothionin exhibits antitumor efficacy against adrenal pheochromocytomas and extra-adrenal paragangliomas (PPGLs) .
|
-
- HY-B1222
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria .
|
-
- HY-B0490R
-
|
|
Bacterial
Fungal
Antibiotic
Parasite
|
Infection
|
|
Hygromycin B (Standard) is the analytical standard of Hygromycin B. This product is intended for research and analytical applications. Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.
|
-
- HY-76260R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Faropenem sodium (Standard) is the analytical standard of Faropenem sodium. This product is intended for research and analytical applications. Faropenem sodium is an orally bioavailable penem antibiotic which can efficiently kill Mycobacterium tuberculosis.
|
-
- HY-126804
-
|
|
Antibiotic
|
Infection
Cancer
|
|
Safracin B, a tetrahydroisoquinoline (THIQ) alkaloid, is a naturally occurring antibiotic from Pseudomonas fluorescens. Safracin B exhibits broad spectrum antimicrobial and strong antitumor activities .
|
-
- HY-111264
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Naphthomycin B is an antibiotic, which is initially isolated from Streptomyces sp. Naphthomycin B exhibits antimicrobial activities against gram positive bacteria and many fungis .
|
-
- HY-N13981
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Arylomycin B2, an antibiotic, is a potent signal peptidase I (SPase I) inhibitor. Arylomycin B2 has anti-Gram-positive bacteria activities .
|
-
- HY-A0107S
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tetracycline-d6 is the deuterium labeled Tetracycline. Tetracycline is a broad-spectrum antibiotic, exhibiting activity against a wide range of gram-positive and gram-negative bacteria.
|
-
- HY-A0246AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Flucloxacillin sodium (Standard) is the analytical standard of Flucloxacillin sodium. This product is intended for research and analytical applications. Flucloxacillin sodium is an active antibiotic against gram-positive and gram-negative bacteria .
|
-
- HY-B0221A
-
-
- HY-108877
-
|
BMY-28142 hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Cefepime hydrochloride is a cephalosporin antibiotic agent. Cefepime hydrochloride has inhibitory activity against human serum paraoxonase-1 (hPON1) with an IC50 value of 21.115 mM .
|
-
- HY-136428S
-
|
|
Isotope-Labeled Compounds
|
Cancer
|
|
Desoxycarbadox-d3 is the deuterium labeled Desoxycarbadox. Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound.
|
-
- HY-106597A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Pirlimycin hydrochloride, a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin hydrochloride acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome .
|
-
- HY-108569
-
|
|
Antibiotic
Bacterial
PPAR
|
Infection
|
|
nTZDpa is an antibiotic. nTZDpa is a PPARG partial agonist. nTZDpa has antibacterial activity. nTZDpa is effective against growing and persistent Staphylococcus aureus by lipid bilayer disruption .
|
-
- HY-19584
-
|
|
Fungal
|
Infection
|
|
Variotin is an Anti-Fungal Agent. Variotin has a strong antibiotic activity on dermatophytes such as Trichophyton, Microsporum, and Epidermophyton, and also pathogenic fungi in internal mycosis such as Blastomyces and Cryptococcus .
|
-
- HY-P0274A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
PGLa TFA, a 21-residue peptide, is an antimicrobial peptide. PGLa TFA is a member of the magainin family of antibiotic peptides found in frog skin and its secretions .
|
-
- HY-B0272S2
-
|
Rifampin-d4; Rifamycin AMP-d4
|
Bacterial
Influenza Virus
Antibiotic
|
Infection
|
|
Rifampicin-d4 is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.
|
-
- HY-17025S
-
|
Ansamycin-d7; LM-427-d7
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Rifabutin-d7 is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.
|
-
- HY-125653
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Kapurimycin A2 is an antitumor antibiotic that can be found in the culture of Streptomyces sp.. Kapurimycin A2 is an active against bacteria, particularly Gram-positive organisms .
|
-
- HY-126532
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Fmoc-Val-Cit-PAB-Duocarmycin TM is a agent-linker conjugate for ADC by using the antitumor antibiotic, Duocarmycin TM, linked via Fmoc-Val-Cit-PAB.
|
-
- HY-10394S
-
|
PNU-100766-d3
|
Bacterial
Antibiotic
|
Infection
|
|
Linezolid-d3 is a deuterium labeled Linezolid (PNU-100766). Linezolid is a synthetic antibiotic that acts by inhibiting the initiation of bacterial protein synthesis[1].
|
-
- HY-17506S
-
|
|
Bacterial
Autophagy
Antibiotic
|
Infection
Cancer
|
|
Azithromycin-d3 is the deuterium labeled Azithromycin. Azithromycin (CP-62993) is a macrolide antibiotic useful for the treatment of a number of bacterial infections[1][2].
|
-
- HY-14881AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Bedaquiline (fumarate) (Standard) is the analytical standard of Bedaquiline (fumarate). This product is intended for research and analytical applications. Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
|
-
- HY-138538
-
|
|
Antibiotic
|
Others
|
|
2-Nitrobenzaldehyde Semicarbazone is a derivative of Semicarbazide. 2-Nitrobenzaldehyde Semicarbazone can be measured as a metabolite marker to detect the widely banned antibiotic Nitrofurazone .
|
-
- HY-N6665R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefquinome (sulfate) (Standard) is the analytical standard of Cefquinome (sulfate). This product is intended for research and analytical applications. Cefquinome sulfate is a cephem antibiotic, which inhibits members of the Enterobacteriaceae .
|
-
- HY-P10233A
-
|
|
Bacterial
|
Infection
|
|
SAAP 148 TFA is an antimicrobial and antibiofilm agent, and exhibits inhibitory efficacy against antibiotic-resistant pathogens, with LC50 of 0.8-12.8 μM .
|
-
- HY-B0506R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Nadifloxacin (Standard) is the analytical standard of Nadifloxacin. This product is intended for research and analytical applications. Nadifloxacin (OPC7251) is a broad-spectrum fluoroquinolone antibiotic that is effective against acne vulgaris.
|
-
- HY-129307
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Gilvocarcin V is an antibiotic with antibacterial activity and can be isolated from Actinomycete. Gilvocarcin V also has anti-tumor activity and can be used in cancer research .
|
-
- HY-B1327S
-
|
7-Chlorotetracycline-d6 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Chlortetracycline-d6 (hydrochloride) is the deuterium labeled Chlortetracycline hydrochloride. Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is a specific and potent calcium ionophore antibiotic, inhibits binding of aminoacyl-tRNA to ribosomes.
|
-
- HY-B0318
-
-
- HY-A0163C
-
|
(E)-Clopenthixol dihydrochloride
|
Antibiotic
Bacterial
Parasite
|
Infection
|
|
trans-Clopenthixol ((E)-Clopenthixol) dihydrochloride is an antibiotic agent, without neuroleptic effect. trans-Clopenthixol can be used to inhibit Pseudomonas aeruginosa and Plasmodium falciparum in vitro .
|
-
- HY-N6739R
-
-
- HY-W008923R
-
|
|
MMP
Bacterial
Parasite
Antibiotic
|
Infection
Cancer
|
|
Doxycycline (monohydrate) (Standard) is the analytical standard of Doxycycline (monohydrate). This product is intended for research and analytical applications. Doxycycline monohydrate is an antibiotic and broad-spectrum metalloproteinase (MMP) inhibitor .
|
-
- HY-105180
-
|
BO-2727 free acid
|
Bacterial
|
Infection
|
|
Lenapenem (BO-2727 free acid), a carbapenem antibiotic, has potent antibacterial activity against Gram-positive and Gram-negative bacteria including P. aeruginosa .
|
-
- HY-105841A
-
|
M 139603
|
Antibiotic
|
Infection
|
|
Tetronasin (M 139603) sodium is a growth-promoting antibiotic with activity against Gram-positive bacteria. Tetronasin sodium is an oral activity that can be administered in the animal's food or water supply .
|
-
- HY-B0343AS
-
-
- HY-N9460
-
|
|
DNA Alkylator/Crosslinker
Antibiotic
|
Cancer
|
|
Sibiromycin is a naturally produced glycosylated pyrrolobenzodiazepines (PBDs). Sibiromycin is also a potent antitumor antibiotic that binds covalently to DNA in the minor groove at the NH2 of guanine .
|
-
- HY-106371
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Siccanin is a succinate dehydrogenase (SDH) inhibitor (IC50=0.9 μM) with species-selective activity. Siccanin also is a antibiotic against pathogenic fungi .
|
-
- HY-106597
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Pirlimycin, a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome .
|
-
- HY-W013266
-
|
Acetylsulfamethoxazole
|
Bacterial
|
Infection
Metabolic Disease
|
|
N4-Acetylsulfamethoxazole (Acetylsulfamethoxazole) is a metabolite of Sulfamethoxazole (HY-B0322). Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic, used for bacterial infections .
|
-
- HY-14800
-
|
RX-1741
|
Bacterial
Antibiotic
|
Infection
|
|
Radezolid (RX-1741) is a oxazolidinone antibiotic. Radezolid is active against Staphylococcus, Chlamydia, and Legionella species, and remains active against Linezolid-resistant strains .
|
-
- HY-W040128
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Kanamycins sulfate is a broad-spectrum antibiotic, can be used in certain severe staphylococcal or Gram-negative bacillary infections. Kanamycin sulfate has certain ototoxicity .
|
-
- HY-W653977
-
|
7-Chlorotetracycline-13C,d3 hydrochloride
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
Parasite
|
Infection
|
|
Chlortetracycline-13C,d3 hydrochloride (7-Chlorotetracycline-13C,d3 hydrochloride) is the 13C- and deuterium labeled Chlortetracycline hydrochloride (HY-B1327). Chlortetracycline hydrochloride is an orally active, selective antibiotic, that inhibits methanogenic bacteria through inhibition of bacterial protein synthesis. Chlortetracycline hydrochloride is a specific and potent calcium ionophore antibiotic, that inhibits binding of aminoacyl-tRNA to ribosomes .
|
-
- HY-127146
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Platensimycin is an antibiotic produced by S. platensis that inhibits gram-positive bacteria by selectively inhibiting cellular lipid biosynthesis (IC50=0.1 μM). Platensimycin targets the β-ketoacyl-acyl-carrier-protein synthase I/II, FabF/B, an enzyme that participates in the biosynthesis of fatty acids (IC50s=48 nM and 160 nM for S.aureus and E.coli enzymes, respectively). Platensimycin is a promising agent for overcoming antibiotic resistance.
|
-
- HY-13588R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefsulodin (sodium) (Standard) is the analytical standard of Cefsulodin (sodium). This product is intended for research and analytical applications. Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC50 value of 16 μM .
|
-
- HY-B1921
-
|
Midecamycin acetate; Ponsinomycin
|
Bacterial
|
Infection
|
|
Miocamycin (Midecamycin acetate) is a derivative of midecamycin (HY-B1908), a macrolide antibiotic that can be isolated from a culture broth of Streptomyces mycarofaciens. Miocamycin has antibacterial properties .
|
-
- HY-B0810AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Pivmecillinam (hydrochloride) (Standard) is the analytical standard of Pivmecillinam (hydrochloride). This product is intended for research and analytical applications. Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic.
|
-
- HY-W327808
-
|
|
Antibiotic
|
Infection
|
|
DL-Lanthionine is a distinctive amino acid and a monosulfide counterpart to cystine, playing a vital role as a component of peptide antibiotics known as lantiobiotics, which encompass well-known examples such as nisin and subtilin.
|
-
- HY-W749146
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Raja 42 is a gamma lactam antibiotic. Raja 42 is effective against a variety of different bacterias, including Gram-positive and Gram-negative bacteria, such as C. difficile strains .
|
-
- HY-B1802B
-
|
A-61827 hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Tosufloxacin (A-61827) hydrochloride is an orally active fluoroquinolone antibiotic. Tosufloxacin hydrochloride shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-B1802C
-
|
A-61827 tosylate
|
Antibiotic
Bacterial
|
Infection
|
|
Tosufloxacin (A-61827) tosylate is an orally active fluoroquinolone antibiotic. Tosufloxacin tosylate shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-B0408AR
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Clindamycin (hydrochloride) (Standard) is the analytical standard of Clindamycin (hydrochloride). This product is intended for research and analytical applications. Clindamycin (hydrochloride) is a semisynthetic lincosamide antibiotic, which inhibits protein synthesis by acting on the 50S ribosomal.
|
-
- HY-114658R
-
|
|
Biochemical Assay Reagents
Antibiotic
|
Cancer
|
|
Daunomycinone (Standard) is the analytical standard of Daunomycinone. This product is intended for research and analytical applications. Daunomycinone (NSC-109351) is a metabolite of daunomycin. Daunomycin is an antibiotic with antitumor activity .
|
-
- HY-B0308R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sparfloxacin (Standard) is the analytical standard of Sparfloxacin. This product is intended for research and analytical applications. Sparfloxacin (CI-978) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity .
|
-
- HY-B0698
-
|
Sch 39720
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Ceftibuten (Sch39720), an antibiotic, is an orally active cephalosporin, possesses potent activity in vitro against a wide range of gram-negative and certain gram-positive pathogens .
|
-
- HY-P4747
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
LL-37 GKE is an active domain of LL-37. LL-37 GKE has antibacterial activity and has potential applications in antibiotics .
|
-
- HY-A0086
-
|
SCH-20569 sulfate
|
Bacterial
Antibiotic
|
Infection
|
|
Netilmicin (sulfate) (SCH-20569 (sulfate)) is an active aminoglycoside antibiotic against most Gram-negative and some Gram-positive bacteria, including certain strains resistant to gentamicin.
|
-
- HY-N5168
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Argimicin B is an antibiotic that can be isolated from Sphingomonas sp.. Argimicin B exhibits algicidal activity against a variety of toxic cyanobacteria with MIC of low micromolar levels .
|
-
- HY-B2060
-
|
Thiamutilin
|
Bacterial
Antibiotic
|
Infection
|
|
Tiamulin (Thiamutilin) is a diterpenic antibiotic that is widely used in pigs and poultry for the control of infectious diseases. Tiamulin is effectively used in the study of airsacculitis, which is primarily caused by Mycoplasma spp .
|
-
- HY-N1944A
-
|
|
Bacterial
|
Infection
|
|
cis-Nerolidol is a sesquiterpene alcohol that can be found in various plants. cis-Nerolidol exhibits antioxidant and antibacterial activities. cis-Nerolidol can also potentiate the action of antibiotics .
|
-
- HY-B2060A
-
|
Thiamutilin fumarate
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Tiamulin (Thiamutilin) fumarate is a diterpenic antibiotic that is widely used in pigs and poultry for the control of infectious diseases. Tiamulin fumarate is effectively used in the study of airsacculitis, which is primarily caused by Mycoplasma spp .
|
-
- HY-N6738
-
|
|
Bacterial
Fungal
Antibiotic
|
Infection
|
|
Bafilomycin B1 is a macrolide antibiotic isolated from Streptomyces sp, inhibits Gram-positive bacteria and fungi, and acts as an inhibitor of K +-dependent ATPase of E. coli .
|
-
- HY-B1802A
-
|
A-61827 tosylate hydrate; T-3262
|
Bacterial
Antibiotic
|
Infection
|
|
Tosufloxacin tosylate hydrate (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-100528
-
|
Nanchangmycin A
|
Bacterial
Antibiotic
Flavivirus
|
Infection
|
|
Nanchangmycin, a polyether antibiotic produced by Streptomyces nanchangensis NS3226, inhibits gram-positive bacteria . Nanchangmycin is a broad spectrum antiviral active against Zika virus .
|
-
- HY-B0875
-
|
SCE-1365 hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Cefmenoxime (SCE-1365) hydrochloride is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .
|
-
- HY-N5169
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Argimicin C is an antibiotic that can be isolated from Sphingomonas sp.. Argimicin C exhibits algicidal activity against a variety of toxic cyanobacteria with MIC of low micromolar levels .
|
-
- HY-W799435
-
|
A-61827 hydrate
|
Antibiotic
Bacterial
|
Infection
|
|
Tosufloxacin (A-61827) tosylate is an orally active fluoroquinolone antibiotic. Tosufloxacin tosylate shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-B0898
-
|
sodium ceftiofur
|
Bacterial
Antibiotic
|
Infection
|
|
Ceftiofur sodium (sodium ceftiofur) is a semisynthetic antibiotic with antimicrobial activity against a wide range of Gram-positive and Gram-negative bacteria, aerobic and anaerobic, targeting livestock .
|
-
- HY-125163
-
|
8-O-Methyltetrangomycin; 6-Deoxy-8-O-methylrabelomycin
|
Bacterial
Antibiotic
|
Infection
|
|
MM 47755 (8-O-Methyltetrangomycin; 6-Deoxy-8-O-methylrabelomycin) is an antibiotic with antibacterial activity. MM 47755 can be isolated from Streptomyces .
|
-
- HY-N13880
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Adustin, an antifungal antibiotic, is a polypeptide with translation-inhibiting activity. Adustin inhibits translation in a cell-free rabbit reticulocyte lysate system with an IC50 of 0.34 μM .
|
-
- HY-B1802
-
|
A-61827
|
Antibiotic
Bacterial
|
Infection
|
|
Tosufloxacin (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-N7123R
-
|
Sulphacetamide (Standard)
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfacetamide (Standard) is the analytical standard of Sulfacetamide. This product is intended for research and analytical applications. Sulfacetamide (Sulphacetamide), a bacteriostatic sulphonamide, is a popular antibiotic prescribed for treating ocular infections .
|
-
- HY-B0300S
-
-
- HY-P3270
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Capreomycin is a macrocyclic peptide antibiotic. Capreomycin can be used for anti-multidrug-resistant-tuberculosis research. Capreomycin can inhibit phenylalanine synthesis in in mycobacterial ribosomes translation
|
-
- HY-B0875A
-
|
SCE-1365
|
Antibiotic
Bacterial
|
Infection
|
|
Cefmenoxime (SCE-1365) is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .
|
-
- HY-B0698B
-
|
Sch 39720 monohydrate
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Ceftibuten (Sch39720) monohydrate, an antibiotic, is an orally active cephalosporin, possesses potent activity in vitro against a wide range of gram-negative and certain gram-positive pathogens .
|
-
- HY-B1824R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefpirome sulfate (Standard) is the analytical standard of Cefpirome sulfate. This product is intended for research and analytical applications. Cefpirome sulfate (HR-810 sulfate) is a fourth generation cephalosporin antibiotic.
|
-
- HY-116010R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Oleandomycin (Standard) is the analytical standard of Oleandomycin. This product is intended for research and analytical applications. Oleandomycin is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity.
|
-
- HY-119673
-
|
|
Antibiotic
|
Others
|
|
Lincophenicol is a hybrid antibiotic that has the activity of inhibiting the puromycin reaction catalyzed by Escherichia coli ribosomal peptidyl transferase and also inhibits the binding of specific compounds to the Escherichia coli ribosome.
|
-
- HY-106959
-
|
(8S)-8-Fluoroerythromycin A; P-0501A
|
Antibiotic
Bacterial
|
Infection
|
|
Flurithromycin ((8S)-8-Fluoroerythromycin A) is an orally active broad spectrum antibiotic. Flurithromycin can be used in the research of bacterial infections .
|
-
- HY-131146R
-
|
|
Antibiotic
|
Infection
|
|
AMOZ (Standard) is the analytical standard of AMOZ. This product is intended for research and analytical applications. AMOZ, a tissue bound metabolite of Furaltadone, Furaltadone is a synthetic nitrofuran antibiotic widely used
|
-
- HY-A0059R
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Nifuratel (Standard) is the analytical standard of Nifuratel. This product is intended for research and analytical applications. Nifuratel (NF 113, SAP 113) is a broad-spectrum antibiotic with activity against bacteria, fungi and trichomonas.
|
-
- HY-W007056
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-N-me-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptide antibiotics with antibacterial activity against Pseudomonas aeruginosa .
|
-
- HY-B0441A
-
|
Nebramycin Factor 6 sulfate; Deoxykanamycin B sulfate
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Tobramycin sulfate (Nebramycin Factor 6 sulfate) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms .
|
-
- HY-125633
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Kapurimycin A3 is an antitumor and antibacterial antibiotic. Kapurimycin A3 has DNA binding and breakage activity. Kapurimycin A3 can be isolated from Streptomyces .
|
-
- HY-142127
-
|
Vistamycin; SF-733
|
Bacterial
Antibiotic
PDI
|
Infection
|
|
Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of PDI .
|
-
- HY-17460A
-
|
BMS284756 Mesylate hydrate
|
Bacterial
Topoisomerase
DNA/RNA Synthesis
Antibiotic
|
Infection
|
|
Garenoxacin (BMS284756) Mesylate hydrate is an orally active quinolone antibiotic and has a broad spectrum of activity against a wide array of gram-positive and gram-negative bacteria, anaerobes, and fastidious organisms .
|
-
- HY-101162
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
SGD-1910 is a agent-linker conjugate for ADC by using the antitumor antibiotic, pyrrolobenzodiazepine (PBD, a cytotoxic DNA crosslinking), linked via the cleavable linker MC-Val-Ala .
|
-
- HY-106758
-
|
|
Antibiotic
|
Infection
|
|
Cefuzonam sodium is a second-generation cephalosporin antibiotic with activity against Staphylococcus aureus, which is resistant to most third-generation cephalosporins. Cefuzonam sodium is effective for preventing infection after cesarean delivery .
|
-
- HY-N7111R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sultamicillin (tosylate) (Standard) is the analytical standard of Sultamicillin (tosylate). This product is intended for research and analytical applications. Sultamicillin tosylate is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .
|
-
- HY-76260
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Faropenem sodium is an orally bioavailable penem antibiotic. Faropenem sodium regulates inorganic phosphate transporter Npt1. Faropenem sodium inhibits M. tuberculosis (MIC of 1.3 μg/mL) and B. anthracis .
|
-
- HY-N6670R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefotetan (Standard) is the analytical standard of Cefotetan. This product is intended for research and analytical applications. Cefotetan is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis .
|
-
- HY-B0271
-
|
Pyrazinecarboxamide; Pyrazinoic acid amide
|
Bacterial
Autophagy
Antibiotic
|
Infection
|
|
Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis.
|
-
- HY-17035
-
|
|
Parasite
Antibiotic
Bacterial
|
Infection
|
|
Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model .
|
-
- HY-N6643
-
|
|
EBV
Fungal
Bacterial
|
Infection
Inflammation/Immunology
|
|
Rubropunctamine is a redMonascus pigment. Not only Rubropunctamine exerts antibiotic action against bacteria but also against some yeast and filamentous fungi strains. Rubropunctamine has potential embryotoxicity and teratogenicity .
|
-
- HY-111428
-
|
PLM D1
|
Antibiotic
|
Infection
|
|
Phleomycin D1 (PLM D1), a glycopeptide antibiotic, is a member of the Bleomycin/Phleomycin family. Phleomycin D1 causes cell death by binding and cleaving DNA .
|
-
- HY-A0256BR
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Clavulanate (lithium) (Standard) is the analytical standard of Clavulanate (lithium). This product is intended for research and analytical applications. Clavulanate lithium is a potent β-lactamase inhibitor and acts as an antibiotic .
|
-
- HY-P1975
-
|
Basifungin
|
Fungal
Parasite
|
Infection
Inflammation/Immunology
|
|
Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has antifungal and antiparasitic activity .
|
-
- HY-B0706AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Flomoxef (sodium) (Standard) is the analytical standard of Flomoxef (sodium). This product is intended for research and analytical applications. Flomoxef sodium is a oxacephem group antibiotic, with excellent activity against various Gram-positive bacteria .
|
-
- HY-139105
-
|
|
Microtubule/Tubulin
|
Infection
Cancer
|
|
20-O-Demethyl-AP3 is a minor metabolite of Ansamitocin P-3. Ansamitocin P-3, a microtubule inhibitor, is a macrocyclic antitumor antibiotic .
|
-
- HY-B0502R
-
-
- HY-B0529
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Azlocillin, an antibiotic, is a semisynthetic penicillin, and has broad-spectrum antibacterial activity. Azlocillin is active against drug-tolerant B. burgdorferi sensu stricto JLB31 infection .
|
-
- HY-W747311
-
-
- HY-13234S
-
-
- HY-B0129
-
-
- HY-131107
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefpodoxime proxetil impurity B is an impurity of Cefpodoxime proxetil (HY-N7101). Cefpodoxime Proxetil is a first oral and broad spectrum antibiotic that belongs to the third generation of cephalosporin .
|
-
- HY-122386
-
|
Mocimycin; Delvomycin
|
Bacterial
Antibiotic
|
Infection
|
|
Kirromycin (Mocimycin) is an antibiotic produced by Streptomyces collinus Tu 365. Kirromycin is a bacterial protein synthesis inhibitor that immobilizes elongation factor Tu (EF-Tu) on the elongating ribosome .
|
-
- HY-129435
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Altromycin E is an antibiotic, that exhibits antibacterial against Streptococci and Staphylococci with MIC of 0.2-3.12 μg/mL. Altromycin E can be used in anti-tumor research .
|
-
- HY-17460
-
-
- HY-A0269S
-
-
- HY-B0502AS
-
-
- HY-N7115R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sultamicillin (Standard) is the analytical standard of Sultamicillin. This product is intended for research and analytical applications. Sultamicillin is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .
|
-
- HY-B0455A
-
|
SC47111A
|
Bacterial
Antibiotic
|
Infection
|
|
Lomefloxacin (SC47111A) is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. .
|
-
- HY-B0555BS
-
-
- HY-A0279A
-
|
Mikamycin B; Mikamycin IA
|
Bacterial
Antibiotic
|
Infection
|
|
Pristinamycin IA (Mikamycin B) is a cycle-peptidic macrolactone antibiotic. Pristinamycin IA is a substrate of P-glycoprotein and inhibits its function. Pristinamycin IA is active against StaphyloEoccus and Srreptococcus .
|
-
- HY-N13292
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Actinorhodin is a blue-pigmented, redox-active microbial secondary metabolite. Actinorhodin is a potent, bacteriostatic, pH-responsive antibiotic. Actinorhodin exhibits antimicrobial activity against Gram-positive bacteria .
|
-
- HY-139071
-
|
|
Amino Acid Derivatives
|
Others
|
|
Boc-D-Leu-OSu is an amino acids building block. Boc-D-Leu-OSu can be used to synthesize analogues of gastrin antagonist and antibiotic Gramicidin S .
|
-
- HY-130337
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Teicoplanin A2-2 is a glycopeptide antibiotic. Teicoplanin A2-2 exhibits antibacterial activity, particularly against coagulase-negative staphylococci (CNS). Teicoplanin A2-2 inhibits bacterial cell wall synthesis by competitively binding to the terminal D-Ala-D-Ala peptide bonds in the cell wall synthesis process, leading to bacterial death. Teicoplanin A2-2 can be used for research into bacterial resistance mechanisms and the development of new antibiotics .
|
-
- HY-B1282A
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Sulfaquinoxaline sodium salt is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections .
|
-
- HY-W154333
-
|
|
Antibiotic
|
Infection
|
|
H-Arg-OtBu (dihydrochloride) is a membrane-targeting antimicrobial. H-Arg-OtBu (dihydrochloride) targets the negatively charged bacterial membrane via a combination of electrostatic and hydrophobic interactions. H-Arg-OtBu (dihydrochloride) can be used for bacterial infections diseases research .
|
-
- HY-B1282
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections .
|
-
- HY-N8228
-
|
|
Bacterial
|
Infection
Inflammation/Immunology
Cancer
|
|
17-Hydroxyneomatrine, extracted from Sophora flavescens, can well inhibit the growth of human cervical carcinoma Hela cells, has the wide-range antibacterial, anti-allergy, anti-tumor, anti-arrhythmia, swelling-subsiding diuresis, immunizing, and biological regulation functions .
|
-
- HY-W353258
-
|
BAY 12-8039 monohydrate
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Moxifloxacin (BAY 12-8039) hydrochloride monohydrate is an orally active bacterial inhibitor that is effective against Streptococcus pneumoniae. Moxifloxacin hydrochloride monohydrate can be used in tuberculosis research .
|
-
- HY-129379
-
|
|
ADC Cytotoxin
|
Cancer
|
|
DC0-NH2 is an effector moiety for ADC and a simplified analog of DC1 with better stability. DC0-NH2 is about 1000-fold more cytotoxic than commonly used anticancer agents (ex. Doxorubicin). DC0-NH2 can bind to the minor groove of DNA, followed by alkylation of adenine residues by its propabenzindole (CBI) component .
|
-
- HY-A0162R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Bictegravir (sodium) (Standard) is the analytical standard of Bictegravir (sodium). This product is intended for research and analytical applications. Bictegravir sodium is a potent inhibitor of HIV-1 integrase, with an IC50 of 7.5 nM. Bictegravir sodium exhibits potent and selective anti-HIV activity and low cytotoxicity .
|
-
- HY-W127442R
-
|
|
Bacterial
Antibiotic
|
Others
|
|
DPPC (Standard) is the analytical standard of DPPC. This product is intended for research and analytical applications. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .
|
-
- HY-W353258R
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Moxifloxacin (hydrochloride monohydrate) (Standard) is the analytical standard of Moxifloxacin (hydrochloride monohydrate). This product is intended for research and analytical applications. Moxifloxacin (BAY 12-8039) hydrochloride monohydrate is an orally active bacterial inhibitor that is effective against Streptococcus pneumoniae. Moxifloxacin hydrochloride monohydrate can be used in tuberculosis research .
|
-
- HY-161685
-
-
- HY-B1282R
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Sulfaquinoxaline (Standard) is the analytical standard of Sulfaquinoxaline. This product is intended for research and analytical applications. Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections .
|
-
- HY-P5620
-
|
|
Bacterial
|
Infection
|
|
DFTamP1 is an antimicrobial peptide against Staphylococcus aureus USA300 activity (MIC is 3.1 μM) .
|
-
- HY-119067
-
-
- HY-B1282AR
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
3β-Ursodeoxycholic acid (Standard) is the analytical standard of 3β-Ursodeoxycholic acid. This product is intended for research and analytical applications. 3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) is a bile acid. 3β-Ursodeoxycholic acid shows good tolerance and well intestinal absorption by oral adminstation. 3β-Ursodeoxycholic acid can be isomerized by intestinal and hepatic enzymes to yield UDCA .
|
-
- HY-B0396
-
-
- HY-129469
-
|
|
Antibiotic
|
Infection
|
|
Saframycin S is an antibiotic with a racemomycin group that exhibits inhibitory activity against Ehrlich ascites tumors. The LD50 of Saframycin S in ddY mice is 3.2 mg/kg (i.p.) .
|
-
- HY-N13910
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Alnumycin is a naphthoquinone antibiotic with a narrow-spectrum antimicrobial activity against Gram-positive bacteria. Alnumycin inhibits the growth of K562 human leukemia cells with an IC50 of 0.53 μg/mL .
|
-
- HY-N9362
-
|
|
Antibiotic
|
Infection
|
|
Emodinanthrone, an anthraquinone, is a sprecursor of Emodin (HY-14393) with antibiotic activity. Emodinanthrone inhibits respiration-driven solute transport at micromolar concentrations in membrane vesicles of Escherichia coli .
|
-
- HY-147643
-
|
|
Aminoacyl-tRNA Synthetase
|
Infection
|
|
Aminoacyl tRNA synthetase-IN-2 (Compound 14) is an aminoacyl-tRNA synthetase (aaRS) inhibitor. Aminoacyl tRNA synthetase-IN-2 can be used for development of a new family of antibiotics .
|
-
- HY-B0525
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Carbenicillin is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin can interfere the cell wall synthesis while displaying low toxicity to plant tissue .
|
-
- HY-17412S
-
|
|
Isotope-Labeled Compounds
Antibiotic
|
Others
|
|
Minocycline-d6 hydrochloride is deuterated labeled Minocycline hydrochloride (HY-17412). Minocycline hydrochloride is an orally effective semi-synthetic tetracycline antibiotic and HIF-1α inhibitor .
|
-
- HY-B1358
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Lincomycin hydrochloride monohydrate is a narrow-spectrum antibiotic, has similar effects to erythromycin, which has a good effect on gram-positive coccus, mainly used to inhibit the synthesis of bacterial cell protein .
|
-
- HY-B0474R
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Tetracycline (hydrochloride) (Standard) is the analytical standard of Tetracycline (hydrochloride). This product is intended for research and analytical applications. Tetracycline (hydrochloride) is a broad-spectrum antibiotic, exhibiting activity against a wide range of gram-positive and gram-negative bacteria.
|
-
- HY-B0330DS
-
-
- HY-B0502AS1
-
-
- HY-B0502A
-
|
BAY Vp 2674 monohydrochloride; PD160788 monohydrochloride
|
Bacterial
Antibiotic
Endogenous Metabolite
Orthopoxvirus
|
Infection
|
|
Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis. Enrofloxacin monohydrochloride shows inhibitory activity against vaccinia virus (VV).
|
-
- HY-108971
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Demecycline, a tetracycline antibiotic, is the C6-demethylated derivative of Tetracycline (HY-A0107) against bacterial infections including pneumonia and other respiratory tract infections .
|
-
- HY-B0272S
-
|
Rifampin-d3; Rifamycin AMP-d3
|
Bacterial
Influenza Virus
Antibiotic
|
Infection
|
|
Rifampicin-d3 is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities[1][2].
|
-
- HY-17025R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Rifabutin (Standard) is the analytical standard of Rifabutin. This product is intended for research and analytical applications. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.
|
-
- HY-24470B
-
-
- HY-B1256A
-
|
Kefurox
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Cefuroxime is an orally active second-generation cephalosporin antibiotic with increased stability to β-lactamase. Cefuroxime has a broad spectrum activity against Gram-positive and Gram-negative bacteria .
|
-
- HY-B0455
-
|
SC47111A hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Lomefloxacin (SC47111A) hydrochloride is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin hydrochloride is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. .
|
-
- HY-B0698A
-
|
Sch-39720 dihydrate
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Ceftibuten (Sch-39720) dihydrate, an antibiotic, is an orally active cephalosporin, possesses potent activity in vitro against a wide range of gram-negative and certain gram-positive pathogens .
|
-
- HY-123216
-
|
S-1090 free base
|
Antibiotic
Bacterial
|
Infection
|
|
Cefmatilen (S-1090) is an orally-active cephalosporin antibiotic that shows high activity against a variety of Gram-positive and Gram-negative bacteria, including Streptococcus pyogenes and Neisseria gonorrhoeae .
|
-
- HY-17412B
-
|
|
Drug Metabolite
|
Others
|
|
4-Epiminocycline is a Minocycline (HY-17412A) degradation product. Minocycline (HY-17412A) is an antibiotic that has anti-inflammatory, anticancer, antibacterial, immunomodulatory and neuroprotective effects .
|
-
- HY-N8339
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Decatromicin B is an antibiotic. Decatromicin B has potent antibacterial activities against both Gram-positive and Gram-negative bacteria. Decatromicin B can be isolated from Actimonadura sp. .
|
-
- HY-126685
-
-
- HY-109855
-
|
|
Topoisomerase
Antibiotic
Bacterial
|
Infection
|
|
CP-67015, a quinolone antibiotic, is a potent topoisomerase II inhibitor. CP-67015 is a positive direct-acting mutagen in mammalian cells with both gene and chromosomal level effects .
|
-
- HY-17362
-
|
|
Bacterial
Autophagy
Antibiotic
|
Infection
Cancer
|
|
Vancomycin hydrochloride is an antibiotic for the treatment of bacterial infections. It acts by inhibiting the second stage of cell wall synthesis of susceptible bacteria. Vancomycin also alters the permeability of the cell membrane and selectively inhibits ribonucleic acid synthesis.
|
-
- HY-B0522R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Ampicillin (Standard) is the analytical standard of Ampicillin. This product is intended for research and analytical applications. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.
|
-
- HY-N13894
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Auramycin A, an anthracycline antibiotic that shows marked antibacterial activity against Gram-positive bacteria. Auramycin A also exhibits antitumor activity against P388 and L1210 leukemia in mice .
|
-
- HY-B0396A
-
|
L084 hydrochloride
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
|
|
Tebipenem pivoxil (L084) hydrochloride is an orally active antibiotic against a variety of pathogenic bacteria. Tebipenem pivoxil hydrochloride binds penicillin-binding protein (PBP), thereby inhibiting cell wall synthesis .
|
-
- HY-17010
-
|
SB-275833
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Retapamulin (SB-275833) is a topical antibiotic that binds Staphylococcus aureus and E. coli ribosomes with a Kd of 3 nM. Retapamulin can be used in researches of atopic dermatitis and prostate cancer .
|
-
- HY-100760
-
|
Xanthothricin; Toxoflavine; PKF-118-310
|
β-catenin
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor activity . Antibiotic properties.
|
-
- HY-100528A
-
|
Nanchangmycin free acid
|
Bacterial
Antibiotic
Flavivirus
|
Infection
|
|
Dianemycin (Nanchangmycin free acid), a polyether antibiotic produced by Streptomyces nanchangensis NS3226, inhibits gram-positive bacteria . Nanchangmycin is a broad spectrum antiviral active against Zika virus .
|
-
- HY-W415818
-
|
|
Adenosine Deaminase
Antibiotic
|
Cancer
|
|
Oxanosine is an antibiotic isolated from the streptomyces MG265-CF34, which has anti-tumor activity. Oxanosine is also a substrate for adenosine deaminase .
|
-
- HY-A0253R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefacetrile (Standard) is the analytical standard of Cefacetrile. This product is intended for research and analytical applications. Cefacetrile (Cephacetrile) is a broad-spectrum antibiotic that is effective in gram-positive and gram-negative bacterial infection .
|
-
- HY-126906
-
|
|
Antibiotic
P-glycoprotein
|
Cancer
|
|
Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity sup>[2].
|
-
- HY-B1256
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Cefuroxime sodium is an orally active second-generation cephalosporin antibiotic with increased stability to β-lactamase. Cefuroxime sodium has a broad spectrum activity against Gram-positive and Gram-negative bacteria .
|
-
- HY-13725R
-
|
|
Topoisomerase
Autophagy
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Pirarubicin (Standard) is the analytical standard of Pirarubicin. This product is intended for research and analytical applications. Pirarubicin is an anthracycline antibiotics, acts as a topoisomerase II inhibitor, and is a widely used for treatment of various cancers, in particular, solid tumors.
|
-
- HY-B0272S1
-
|
Rifampin-d8; Rifamycin AMP-d8
|
Bacterial
Influenza Virus
Antibiotic
|
Infection
|
|
Rifampicin-d8 (Rifampin-d8) is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.
|
-
- HY-A0269R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Mecillinam (Standard) is the analytical standard of Mecillinam. This product is intended for research and analytical applications. Mecillinam (Amdinocillin), the β-lactam antibiotic, has a broad spectrum of activity against gram-negative organisms .
|
-
- HY-W743944
-
|
|
Apoptosis
|
Inflammation/Immunology
|
|
Tilivalline is an enterotoxin that can be produced by Klebsiella oxytoca. Tilivalline shows cytotoxicity against carcinoma cells. Tilivalline induces epithelial apoptosis. Tilivalline causes antibiotic-associated hemorrhagic colitis (AAHC) .
|
-
- HY-122394
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Thiolactomycin is an antibiotic. Thiolactomycin is active against Gram-negative anaerobes. Thiolactomycin also inhibits malaria and trypanosomes. Thiolactomycin is a FabB inhibitor. Thiolactomycin inhibits the synthesis of fatty acids and mycolic acids .
|
-
- HY-W748013
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cervinomycin A2 is an anti-anaerobic antibiotic that can be isolated from Streptomyces cervicalis. Cervinomycin A2 has a strong inhibitory effect on Clostridium perfringens, Gastrococcus prophylacticus, and Bacteroides fragilis .
|
-
- HY-B0957
-
|
Erythromycin ethyl succinate; EES
|
Bacterial
HIV
Autophagy
Antibiotic
|
Infection
|
|
Erythromycin Ethylsuccinate is an antibiotic useful for the treatment of a number of bacterial infections, has an antimicrobial spectrum similar to or slightly wider than that of penicillin. Erythromycin Ethylsuccinate has antiviral activity against HIV-1.
|
-
- HY-B0318S
-
|
|
Bacterial
Parasite
Apoptosis
Antibiotic
|
Infection
|
|
Metronidazole- 13C2, 15N2 is the 13C-labeled and 15N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
|
-
- HY-B1920A
-
|
EN-141 hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Josamycin (EN-141) hydrochloride is an orally active macrolide antibiotic exhibiting antimicrobial activity against a wide spectrum of pathogens, such as bacteria. The dissociation constant Kd from ribosome for Josamycin hydrochloride is 5.5 nM .
|
-
- HY-A0241
-
|
RP54476
|
Bacterial
Antibiotic
|
Infection
|
|
Dalfopristin (RP54476) is a semisynthetic sulfone antibiotic. Dalfopristin alone has limited antibacterial activity, but synergistically with Quinupristin it has significant bactericidal activity against many pathogenic Gram-positive cocci .
|
-
- HY-121294
-
|
X 14547A
|
Antibiotic
|
Infection
|
|
Indanomycin is an antibiotic of the pyrroloketoindane class, which includes an unusual indane ring structure. It has bactericidal activity against Gram-positive bacteria, with minimum inhibitory concentration (MIC) values of ≤0.2 μg/mL.
|
-
- HY-107164
-
|
4-Hydroxythiomarinol C
|
Antibiotic
Bacterial
|
Infection
|
|
Thiomarinol A (4-Hydroxythiomarinol C) is a potent antibiotic. Thiomarinol A is a hybrid of dithiolopyrrolone and marinolic acid. Thiomarinol A shows antimicrobial activity. Thiomarinol A inhibits MRSA IleRS in a dose-dependent with a Ki app value of 19 nM .
|
-
- HY-N14911
-
|
|
Antibiotic
Bacterial
Fungal
DNA/RNA Synthesis
|
Infection
Cancer
|
|
Actinoplanone A is a polycyclic xanthone antibiotic. Actinoplanone A has strong antimicrobial activities against bacteria and the rice blast fungus. Actinoplanone A is cytotoxic to various tumor cells and has an inhibitory effect on DNA synthesis .
|
-
- HY-N7114
-
|
|
Antibiotic
Bacterial
|
Infection
Metabolic Disease
|
|
Chloramphenicol succinate is a proagent of Chloramphenicol, with Haemotoxicity. Chloramphenicol succinate also is an antibiotic. Chloramphenicol succinate is a competitive substrate and inhibitor of succinate dehydrogenase (SDH) that is the possible reason for its toxicity .
|
-
- HY-B0522S
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Ampicillin-d5 is the deuterium labeled Ampicillin. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria[1][2][3].
|
-
- HY-12459
-
|
|
Bacterial
|
Infection
|
|
Pyrindamycin B is an antibiotic, actives against gram-positive and gram-negative bacterias, and exhibits strong therapeutic effects against both agent-sensitive and resistant cells of P388 leukemia in mice .
|
-
- HY-125637
-
|
Aabomycin A2
|
Antibiotic
Fungal
ATP Synthase
|
Infection
|
|
Venturicidin B (Aabomycin A2) is a macrolide antibiotic isolated from Streptomyces sp., used as an antifungal agent, a potent inhibitor of the mitochondrial F0-ATP synthase complex .
|
-
- HY-118893
-
|
|
Antibiotic
Bacterial
Fungal
Molecular Glues
|
Infection
Cancer
|
|
Asukamycin, a manumycin-type metabolite, could be isolated from Streptomyces nodosus subsp. asukaensis. Asukamycin is an antibiotic and has antimicrobial activity. Asukamycin inhibits growth of various tumor cell lines .
|
-
- HY-B1275R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cephalothin (sodium) (Standard) is the analytical standard of Cephalothin (sodium). This product is intended for research and analytical applications. Cephalothin sodium is a first-generation cephalosporin antibiotic with broad antibacterial activity and is effective against Gram-positive and Gram-negative bacteria.
|
-
- HY-137898
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Avilamycin A is an oral active antibiotic. Avilamycin A is active against veterinary isolates of C. perfringens (MICs ≤ 0.06-0.5 mg/L) and B. hyodysenteriae (MICs = 12.5-100 μg/ml) .
|
-
- HY-B1267S1
-
|
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Sulfaguanidine- 13C6 is the 13C6 labeled Sulfaguanidine. Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery.
|
-
- HY-B0330DR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
(R)-Ofloxacin (Standard) is the analytical standard of (R)-Ofloxacin. This product is intended for research and analytical applications. (R)-Ofloxacin (Dextrofloxacin) is an antibiotic useful for the treatment of a number of bacterial infections . Antibacterial activity .
|
-
- HY-N5167
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Argimicin A is an antibiotic that can be isolated from Sphingomonas sp.. Argimicin A exhibits algicidal activity against toxic cyanobacteria, inhibits M. viridis and M. aeruginosa with IC50 of 12 ng/mL and 100 ng/mL .
|
-
- HY-136295
-
|
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
|
Quinaldopeptin, a quinomycin antibiotic isolated from the culture of Streptoverticillium album strain, is highly active against Gram-positive bacteria and anaerobes and strongly cytotoxic against cultured B16 melanoma cells .
|
-
- HY-136828
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
LL-BM123α is a basic antibiotic isolated from Nocardia sp. LL-BM123α exhibits moderate activity against Gram-negative bacteria.
|
-
- HY-G0016
-
|
MADDS; Monoacetyldapsone
|
Drug Metabolite
|
Others
|
|
N-Acetyl dapsone (MADDS) is the major metabolite of Dapsone (HY-B0688). Dapsone is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities .
|
-
- HY-139798
-
|
|
Bacterial
|
Infection
|
|
Iboxamycin is a potent antibiotic candidate bearing a fused bicyclic amino acid residue. Iboxamycin is orally bioavailable, safe and effective in researching both Gram-positive and Gram-negative bacterial infections in mice .
|
-
- HY-106571R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefteram pivoxil (Standard) is the analytical standard of Cefteram pivoxil. This product is intended for research and analytical applications. Cefteram pivoxil (Ro 19-5248), an orally active cephalosporin antibiotic, is used for bacterial infections .
|
-
- HY-B1078
-
-
- HY-B1920
-
|
EN-141
|
Bacterial
Antibiotic
|
Infection
|
|
Josamycin (EN-141) is an orally active macrolide antibiotic exhibiting antimicrobial activity against a wide spectrum of pathogens, such as bacteria. The dissociation constant Kd from ribosome for Josamycin is 5.5 nM .
|
-
- HY-18258S
-
-
- HY-B0526S
-
-
- HY-136512
-
|
|
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Streptazolin is an antibiotic. Streptazolin increases bacterial killing and elaboration of immunostimulatory cytokines by macrophages in vitro. Streptazolin stimulates the macrophage NF-κB pathway via PI3K signaling .
|
-
- HY-B1175R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
(2S,5R,6R)-Ticarcillin (disodium) (Standard) is the analytical standard of (2S,5R,6R)-Ticarcillin (disodium). This product is intended for research and analytical applications. (2S,5R,6R)-Ticarcillin disodium is an injectable antibiotic for the treatment of Gram-negative bacteria, particularly Pseudomonas aeruginosa. It is also one of the few antibiotics capable of treating Stenotrophomonas maltophilia infections.
|
-
- HY-107579R
-
|
|
GPR109A
|
Cardiovascular Disease
|
|
(2S,5R,6R)-Ticarcillin (disodium) (Standard) is the analytical standard of (2S,5R,6R)-Ticarcillin (disodium). This product is intended for research and analytical applications. (2S,5R,6R)-Ticarcillin disodium is an injectable antibiotic for the treatment of Gram-negative bacteria, particularly Pseudomonas aeruginosa. It is also one of the few antibiotics capable of treating Stenotrophomonas maltophilia infections.
|
-
- HY-107813R
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Streptomycin (Standard) is the analytical standard of Streptomycin. This product is intended for research and analytical applications. Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes .
|
-
- HY-122062R
-
|
|
Insecticide
|
Others
|
|
Erythromycin C (Standard) is the analytical standard of Erythromycin C. This product is intended for research and analytical applications. Erythromycin C is an antibiotic. Erythromycin C could be isolated from the fermentation process of the penicillium Streptomyces erythreus .
|
-
- HY-B0526R
-
|
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
Cancer
|
|
Flumequine (Standard) is the analytical standard of Flumequine. This product is intended for research and analytical applications. Flumequine (R-802) is a quinolone antibiotic, and acts as a topoisomerase II inhibitor, with an IC50 of 15 μM (3.92 μg/mL).
|
-
- HY-B1340S
-
|
|
Bacterial
Antibiotic
Endogenous Metabolite
|
Infection
|
|
Carbadox-d3 is the deuterium labeled Carbadox. Carbadox is a quinoxaline-di-N-oxide antibiotic compound which is widely fed to nursery-age pigs to control enteric diseases and improve feed efficiency.
|
-
- HY-135176
-
|
|
Endogenous Metabolite
|
Cancer
|
|
13-Dihydrocarminomycin (compound D788-12) is the major metabolite of the antitumor antibiotic Carminomycin (HY-B2171). 13-Dihydrocarminomycin has weak antitumor activity .
|
-
- HY-121144R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefazedone (Standard) is the analytical standard of Cefazedone. This product is intended for research and analytical applications. Cefazedone (Refosporen), a first-generation cephalosporin, is a time-dependent antibiotic with activity against Gram-positive and Gram-negative bacteria .
|
-
- HY-B0771
-
|
SCE-2787
|
Bacterial
Antibiotic
|
Infection
|
|
Cefozopran (SCE-2787) is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms .
|
-
- HY-100589
-
|
Sch 21420 sulfate
|
Bacterial
Antibiotic
|
Infection
|
|
Isepamicin sulfate (Sch 21420 sulfate) is a broad spectrum aminoglycoside antibiotic. Isepamicin sulfate exhibits considerable antimicrobial activity against Gram-negative non-fermenters in a region with high antimicrobial resistance .
|
-
- HY-P0230
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Teixobactin is a potent antibiotic. Teixobactin shows antibacterial activity for gram-negative bacteria. Teixobactin inhibits cell wall synthesis by binding to a highly conserved motif of lipid II and lipid III .
|
-
- HY-I0447R
-
|
|
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
|
4-Aminosalicylic acid (Standard) is the analytical standard of 4-Aminosalicylic acid. This product is intended for research and analytical applications. 4-Aminosalicylic acid (ASA) is an orally active antibiotic and has the potential to treat tuberculosis .
|
-
- HY-126569
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Efrotomycin is an orally active antibiotic. Efrotomycin can be isolated from the Streptomyces Lactamdurans. Efrotomycin has insignificant effect on Salmonella typhimurium quantity, duration, shedding rate, and antimicrobial susceptibility in infected pigs .
|
-
- HY-17442R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Azathramycin (Standard) is the analytical standard of Azathramycin. This product is intended for research and analytical applications. Azathramycin (Azaerythromycin A) is an antibiotic that targets ribosomes and possesses antibacterial activity, which can be used in research related to infectious diseases .
|
-
- HY-N8273
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Gliovirin is an antibiotic active against Pythium ultimum. Gliovirin is isolated from Gliocla-dium virens. Gliovirin may be derived from L,L-phenylalanine anhydride, which is also isolated from G. virens .
|
-
- HY-107330
-
|
|
Antibiotic
|
Others
|
|
(6R,7S)-Cefminox sodium heptahydrate is an isomer of Cefminox sodium heptahydrate. Cefminox sodium heptahydrate is a β-lactam cephalosporin antibiotic, which exhibits a broad spectrum of antibacterial activity .
|
-
- HY-129623R
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Nigericin (sodium salt) (Standard) is the analytical standard of Nigericin (sodium salt). This product is intended for research and analytical applications. Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus that works by acting as an H+, K+, and Pb2+ ionophore, a NLRP3 activator .
|
-
- HY-B1244R
-
|
|
Parasite
Antibiotic
|
Infection
|
|
Dimetridazole (Standard) is the analytical standard of Dimetridazole. This product is intended for research and analytical applications. Dmetridazole (1,2-Dimethyl-5-nitroimidazole), a nitroimidazole-based antibiotic, combats protozoan infections .
|
-
- HY-123162A
-
|
Fortimicin A disulfate; KW-1070 disulfate
|
Antibiotic
Bacterial
|
Infection
|
|
Astromicin disulfate is a water-soluble aminoglycoside antibiotic that can be isolated from the genus Micromonospora. Astromicin disulfate exhibits broad spectrum antibacterial activity against gram positive and negative bacteria .
|
-
- HY-N13895
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Auramycin B, an anthracycline antibiotic that shows marked antibacterial activity against Gram-positive bacteria. Auramycin B also exhibits antitumor activity against P388 and L1210 leukemia in mice .
|
-
- HY-N7095
-
|
CTZ
|
Bacterial
Antibiotic
|
Infection
|
|
Ceftezole (CTZ) is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria. Ceftezole (CTZ) is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity .
|
-
- HY-114798
-
-
- HY-B1267S
-
|
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Sulfaguanidine-d4 is the deuterium labeled Sulfaguanidine. Sulfaguanidine, belongs to the class of sulfonamide agent, is an orally active antibiotic. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery[1][2].
|
-
- HY-101967
-
|
|
DNA/RNA Synthesis
Bacterial
|
Infection
|
|
GSK 299423 is an antibiotic agent.GSK299423 shows potent inhibition of supercoiling by DNA gyrase from S. aureus(IC50=14 nM）and Escherichia coli(IC50=100 nM .
|
-
- HY-B1374R
-
|
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
|
Florfenicol (Standard) is the analytical standard of Florfenicol. This product is intended for research and analytical applications. Florfenicol ((-)-Florfenicol) is an orally active broad-spectrum antibacterial antibiotic with anti-inflammatory, pro apoptotic, and immunomodulatory functions .
|
-
- HY-N7096
-
|
CTZ sodium
|
Bacterial
Antibiotic
|
Infection
|
|
Ceftezole sodium (CTZ sodium) is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria. Ceftezole sodium (CTZ sodium) is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity .
|
-
- HY-B0525A
-
|
Sodium carbenicillin
|
Antibiotic
Bacterial
|
Infection
|
|
Carbenicillin disodium (Sodium carbenicillin) is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin disodium can interfere the cell wall synthesis while displaying low toxicity to plant tissue .
|
-
- HY-133178R
-
|
|
Ephrin Receptor
|
Cancer
|
|
Azathramycin (Standard) is the analytical standard of Azathramycin. This product is intended for research and analytical applications. Azathramycin (Azaerythromycin A) is an antibiotic that targets ribosomes and possesses antibacterial activity, which can be used in research related to infectious diseases .
|
-
- HY-120809
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Spiramycin III (SPMIII) is a main component of Spiramycin. Spiramycin (HY-100593) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect .
|
-
- HY-168799
-
-
- HY-17560
-
-
- HY-B0226
-
|
Nitrofural
|
Bacterial
Antibiotic
|
Infection
|
|
Nitrofurazone (Nitrofural) is a broad spectrum antibiotic that has oral activity. Nitrofurazone is a nitro-aromatic drug. Nitrofurazone is active against both Gram-positive and Gram-negative bacteria .
|
-
- HY-17565R
-
|
|
DNA/RNA Synthesis
Antibiotic
|
Cancer
|
|
Bleomycin (sulfate) (Standard) is the analytical standard of Bleomycin (sulfate). This product is intended for research and analytical applications. Bleomycin sulfate is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin sulfate is an antitumor antibiotic .
|
-
- HY-125546R
-
|
|
Antibiotic
|
Infection
|
|
Erythromycin C (Standard) is the analytical standard of Erythromycin C. This product is intended for research and analytical applications. Erythromycin C is an antibiotic. Erythromycin C could be isolated from the fermentation process of the penicillium Streptomyces erythreus .
|
-
- HY-113627A
-
|
|
Antibiotic
Bacterial
Apoptosis
|
Infection
Inflammation/Immunology
Cancer
|
|
Undecylprodigiosin hydrochloride, a member of the family of prodiginines, is a potent antibiotic. Undecylprodigiosin hydrochloride can selectively induce apoptosis in human breast carcinoma cells independent of p53. Undecylprodigiosin hydrochloride shows immunosuppressive, anticancer properties and antimicrobial activities .
|
-
- HY-117319
-
|
TAK-083; PA-155A
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
|
Indolmycin (TAK-083), an antibiotic, is a competitive inhibitor of prokaryotic tryptophanyl-tRNA synthetase (TrpS). Indolmycin (TAK-083) possesses both anti-viral and anti-bacterial activity .
|
-
- HY-B1690
-
|
|
Antibiotic
Bacterial
Histamine Receptor
|
Infection
|
|
Methdilazine is an orally active antibiotic (histamine antagonist). Methdilazine can inhibit various mycobacterium with MIC values at 5-15 μg/mL in vitro and in vivo, which can be used for the research of infectious diseases .
|
-
- HY-B0771A
-
|
SCE-2787 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Cefozopran (SCE-2787) hydrochloride is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran hydrochloride, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms .
|
-
- HY-B1690A
-
|
|
Antibiotic
Bacterial
Histamine Receptor
|
Infection
|
|
Methdilazine hydrochloride is an orally active antibiotic (histamine antagonist). Methdilazine hydrochloride can inhibit various mycobacterium with MIC values at 5-15 μg/mL in vitro and in vivo, which can be used for the research of infectious diseases .
|
-
- HY-101021
-
|
Ilicicolin D
|
STAT
Apoptosis
Antibiotic
|
Inflammation/Immunology
Cancer
|
|
Ascochlorin (Ilicicolin D), an isoprenoid antibiotic, mediates its anti-tumor effects predominantly through the suppression of STAT3 signaling cascade. Ascochlorin induces apoptosis. Anti-inflammatory activity .
|
-
- HY-U00291
-
|
|
Antibiotic
|
Infection
|
|
Tauroxicum can be used as a nontoxic, non-antimicrobial agent that can replace or supplement the use of antibiotics in the animal husbandry of livestock animals to increase health and general well-being, productivity, feed efficiency and weight gain.
|
-
- HY-Y0055S
-
|
|
Antibiotic
Fungal
Bacterial
|
Infection
Neurological Disease
|
|
Phenothiazine-d8 is the deuterium labeled Phenothiazine. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases[1][2].
|
-
- HY-B1892
-
-
- HY-113627
-
|
|
Antibiotic
Bacterial
Apoptosis
|
Infection
Inflammation/Immunology
Cancer
|
|
Undecylprodigiosin, a member of the family of prodiginines, is a potent antibiotic. Undecylprodigiosin can selectively induce apoptosis in human breast carcinoma cells independent of p53. Undecylprodigiosin shows immunosuppressive, anticancer properties and antimicrobial activities .
|
-
- HY-B1864
-
|
Ksg
|
Antibiotic
Bacterial
|
Infection
|
|
Kasugamycin (Ksg) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation .
|
-
- HY-129347
-
|
T-2636E
|
Antibiotic
Bacterial
|
Infection
|
|
Lankacyclinol A is an orally active antibiotic isolated from Streptomyces rochei. Lankacyclinol A has broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria. Lankacyclinol A exhibits low toxicity in mice .
|
-
- HY-19806
-
|
CXA-101 free base; FR264205 free base
|
Antibiotic
Bacterial
|
Infection
|
|
Ceftolozane (CXA-101 free base; FR264205 free base) is a cephalosporin antibiotic with potent activity againstPseudomonas aeruginosa and strains Enterobacteriaceae, with MICs of 0.5 and 0.25-0.5 mg/L .
|
-
- HY-B1325
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefuroxime Axetil, a proagent of the cephalosporin cefuroxime and an oarl broad spectrum antibiotic, inhibits several gram-positive and gram-negative organisms, including those most frequently associated with various common community-acquired infections .
|
-
- HY-124431
-
|
|
Antibiotic
Bacterial
Parasite
|
Infection
|
|
Kikumycin A is an antibiotic, which can be generated from Streptomyces. Kikumycin A exhibits antibacterial activity against Gram-positive and Gram-negative bacteria. Kikumycin A exhibits antitrichomonal activity, with MIC of 25 μg/mL for Trichomonas foetus .
|
-
- HY-B1484
-
|
Latamoxef sodium; Lamoxactam sodium; LY-127935 sodium
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Moxalactam (Latamoxef) sodium salt is a synthetic oxa-β-lactam antibiotic. Moxalactam sodium salt has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Moxalactam sodium salt inhibits production of β-lactamases .
|
-
- HY-P0269
-
|
Magainin I
|
Bacterial
Fungal
Antibiotic
|
Infection
|
|
Magainin 1 (Magainin I) is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. Magainin 1 exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria .
|
-
- HY-116010A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Oleandomycin phosphate is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes .
|
-
- HY-B1222AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sisomicin (Standard) is the analytical standard of Sisomicin. This product is intended for research and analytical applications. Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria .
|
-
- HY-B0242
-
|
Sulphanilamide
|
Bacterial
Antibiotic
|
Infection
|
|
ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum .
|
-
- HY-N7102R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Ceftiofur (Standard) is the analytical standard of Ceftiofur. This product is intended for research and analytical applications. Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive and gram-negative, aerobic and anaerobic bacteria encountered by domestic animals .
|
-
- HY-B1275AR
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Cephalothin (Standard) is the analytical standard of Cephalothin. This product is intended for research and analytical applications. Cephalotin (Cephalotin) is a beta-lactam antibiotic, inhibits class C β-lactamase AmpC, with an Ki of 0.32 µM .
|
-
- HY-W048478
-
|
|
Bacterial
Antibiotic
|
Others
|
|
2',3'-Dideoxy-5-iodocytidine is used for gene sequencing can be used as an antibiotic. 2',3'-Dideoxy-5-iodocytidine is particular effective against Mycobacterium .
|
-
- HY-112177
-
|
|
Fungal
Mitochondrial Metabolism
Antibiotic
|
Infection
|
|
Myxothiazol, an antifungal antibiotic, is a mitochondrial electron transport chain complex III (bc1 complex) inhibitor. Myxothiazol inhibits the growth of many yeasts and fungi at concentrations between 0.01 and 3 μg/ml .
|
-
- HY-124218
-
|
|
Antibiotic
|
Others
|
|
S 863390 is a compound with the ability to inhibit the intestinal uptake system, which can interact with the intestinal uptake system to inhibit the uptake of β-lactam antibiotics and small peptides while also being transported itself.
|
-
- HY-B1366R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Meclocycline (Sulfosalicylate Salt) (Standard) is the analytical standard of Meclocycline (Sulfosalicylate Salt). This product is intended for research and analytical applications. Meclocycline Sulfosalicylate Salt is a tetracycline antibiotic with broad-spectrum antibacterial activities, preventing skin bacterial infections such as acne vulgaris .
|
-
- HY-122430
-
|
|
Antibiotic
|
Others
|
|
Rosaramicin is a macrolide antibiotic that binds to the ribosomal P site and produces a synergistic effect with puromycin. This synergistic effect may be related to the interaction between the A and P sites. At the same time, its binding activity is affected by multiple substances.
|
-
- HY-B0132S
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Norfloxacin-d5 is the deuterium labeled Norfloxacin. Norfloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase[1][2].
|
-
- HY-B0322R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfamethoxazole (Standard) is the analytical standard of Sulfamethoxazole. This product is intended for research and analytical applications. Sulfamethoxazole (Ro 4-2130) is a sulfonamide bacteriostatic antibiotic, used for bacterial infections. Sulfonamides is a competitive antagonists of para-aminobenzoic acid (PABA) .
|
-
- HY-125496
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
A201A is a aminoacylnucleoside antibiotic with antibacterial activities. A201A is highly effective against Gram-positive and most Gram-negative anaerobic bacteria. A201A inhibits tRNA accommodation during translation .
|
-
- HY-P5561
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aurein 2.2 is a major component of the skin secretion of L.aurea. Aurein 2.2 is an antibiotic with broad-spectrum antibacterial activity against Gram positive bacteria such as Staphylococcus aureus and S. epidermidis .
|
-
- HY-B0455B
-
|
SC47111A (aspartate)
|
Bacterial
Antibiotic
|
Infection
|
|
Lomefloxacin (SC47111A) aspartate is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin aspartate can be used for researching respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. .
|
-
- HY-N0465S
-
|
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Others
|
|
Olaquindox-d4 is the deuterium labeled Olaquindox (HY-N0465) . Olaquindox, a quinoxalin derivative, is an orally active antibiotic. Olaquindox stimulates growth and decreases intestinal mucosal immunity of piglets .
|
-
- HY-123436
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sarubicin B is an active product that can be isolated from the culture filtrate of a Streptomyces strain JA 2861. Sarubicin B is a quinone antibiotic that inhibit Gram-positive bacteria and not active against Gram-negative microorganisms .
|
-
- HY-167651
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
TAN-1057C is a potent antibiotic which exhibits antibacterial activity against Gram-negative and Gram-positive bacteria, including Methicillin (HY-121544)-resistant Staphylococcus aureus .
|
-
- HY-B1484A
-
|
Latamoxef; Lamoxactam; LY-127935
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Moxalactam (Latamoxef) is a synthetic oxa-β-lactam antibiotic. Moxalactam has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Moxalactam inhibits production of β-lactamases .
|
-
- HY-P5708
-
|
Dermaseptin b2
|
Antibiotic
Fungal
Bacterial
|
Infection
|
|
Adenoregulin (Dermaseptin b2) is an antimicrobial peptide antibiotic. Adenoregulin is active against Gram-negative and Gram-positive bacteria, yeast and fungi. Adenoregulin also enhances the binding of agonists to the A1 adenosine receptor .
|
-
- HY-P3119
-
|
Desotamide A
|
Bacterial
|
Infection
|
|
Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces. It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs=16, 12.5, and 32 μg/mL, respectively).
|
-
- HY-P10210
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Paenilagicin is a Gram-positive active antibiotic with a unique diphosphorylated prenyl binding mechanism that does not induce drug resistance. Paenilagicin exhibits a MIC value of 2 μg/mL against multidrug-resistant Gram-positive bacteria .
|
-
- HY-B0132S1
-
|
MK-0366-d8
|
Bacterial
Endogenous Metabolite
Antibiotic
|
Infection
|
|
Norfloxacin-d8 is the deuterium labeled Norfloxacin. Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.
|
-
- HY-124210
-
|
|
Antibiotic
Parasite
|
Infection
Cancer
|
|
Formycin B is an antibiotic, which exhibits antiparasitic activity against Leishmania. Formycin B exhibits toxicity to leukocytes, reversibly decreases neutrophils. Formycin B can be used in research about myeloid leukemia .
|
-
- HY-B1117
-
|
MK-306
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Cefoxitin sodium (MK-306) is a cephamycin antibiotic, often grouped with the second generation cephalosporins, acts by interfering with cell wall synthesis, its activity spectrum includes a broad range of gram-negative and gram-positive bacteria.
|
-
- HY-B0756
-
-
- HY-A0076R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tebipenem (Standard) is the analytical standard of Tebipenem. This product is intended for research and analytical applications. Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa.
|
-
- HY-19825
-
|
|
Topoisomerase
ADC Cytotoxin
Antibiotic
|
Cancer
|
|
Rebeccamycin, an antitumor antibiotic, inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I and has negligible effect on protein kinase C and topoisomerase II .
|
-
- HY-18258R
-
-
- HY-N7545
-
|
|
Antibiotic
Reverse Transcriptase
|
Infection
|
|
Protorubradirin is an antibiotic that can be isolated from Streptomyces achromogenes var. rubradirin together with Rubradirin. Protorubradirin has inhibitory activity against HIV reverse transcriptase. In vitro studies have shown that Protorubradirin also inhibits Staphylococcus aureus strains and Streptococci. In infected mice, subcutaneous injection of Protorubradirin showed in vivo inhibitory efficacy against antibiotic-resistant Staphylococcus aureus strains. However, oral administration may result in a significant reduction in the activity of Protorubradirin, possibly due to faster cleavage of its C-nitroso sugar in the acidic gastric environment compared to Rubradirin .
|
-
- HY-B1455
-
|
|
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
|
Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria .
|
-
- HY-17591S
-
|
Benzylpenicillin-d5 potassium
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Penicillin G-d5 (potassium) is the deuterium labeled Penicillin G potassium. Penicillin G potassium is a fast-acting antibiotic; used to treat bacterial infections that affect the blood, heart, lungs, joints, and genital areas[1][2].
|
-
- HY-14814
-
|
RX-3341; WQ-3034; ABT492
|
Bacterial
Antibiotic
|
Infection
|
|
Delafloxacin (RX-3341; WQ-3034; ABT492) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia .
|
-
- HY-106702
-
|
CI-920
|
Antibiotic
Phosphatase
|
Cancer
|
|
Fostriecin (sodium) (compound 1, CI-920) is an antibiotic with a cytotoxic activity. Fostriecin (sodium) is also an inhibitor of protein phosphatase including PP4 (IC50= 3 nM)and PP2 (IC50=1.5 nM) .
|
-
- HY-N12823
-
|
|
Bacterial
|
Metabolic Disease
|
|
Caprazene is an antimycobacterial compound and precursor molecule for semi-synthetic antibacterial antibiotics, used for studies on tuberculosis and Mycobacterium avium complex infections, which can be isolated from the acid-treated caprazamycin (CPZ) A-G mixture .
|
-
- HY-14603R
-
|
Iodochlorohydroxyquinoline (Standard)
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Fungal
Autophagy
Mitophagy
Antibiotic
Parasite
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Infection
Cancer
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Clioquinol (Standard) is the analytical standard of Clioquinol. This product is intended for research and analytical applications. Clioquinol (Iodochlorhydroxyquin) is a topical antifungal agent with anticancer activity. Clioquinol acts as an oral antimicrobial agent for the research of diarrhea and skin infections. Antibiotic .
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- HY-B1174R
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Antibiotic
Bacterial
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Infection
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Bekanamycin (Standard) is the analytical standard of Bekanamycin. This product is intended for research and analytical applications. Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .
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- HY-120203
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Antibiotic
Bacterial
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Infection
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DA 1131 is an anionic Carbapenem antibiotic. DA 1131 has broad spectrum antibacterial activity for both gram-positive and gram-negative organisms. DA 1131 is resistant to degradation by various types of β-lactamases .
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- HY-B1825
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Antibiotic
Bacterial
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Infection
Cancer
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Cefoxitin, a β-lactam antibiotic, is a broad-spectrum, second-generation cephalosporin. Cefoxitin has a broad spectrum antibacterial activity which includes anaerobic as well as Gram-positive and Gram-negative aerobic bacteria .
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- HY-P1974
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WF11899A
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Antibiotic
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Infection
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FR901379 (WF11899A) is a novel echinocandin-type lipopeptide antibiotic. FR901379 is primarily produced by mutant strain M-7 of Coleophoma empetri F-11899 (FERM BP-2635) .
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- HY-B1071R
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Bacterial
Autophagy
Antibiotic
Parasite
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Infection
Cancer
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Lasalocid (Standard) is the analytical standard of Lasalocid. This product is intended for research and analytical applications. Lasalocid (Lasalocid-A; Ionophore X-537A; Antibiotic X-537A) is an antibacterial and anticoccidial agent used in feed additives.
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- HY-B0522AR
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Bacterial
Antibiotic
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Infection
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Ampicillin (sodium) (Standard) is the analytical standard of Ampicillin (sodium). This product is intended for research and analytical applications. Ampicillin sodium (D-(-)-α-Aminobenzylpenicillin sodium salt) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .
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- HY-14283
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NND 502
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Fungal
Antibiotic
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Infection
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Luliconazole (NND 502)?is a topical antifungal imidazole antibiotic with broad-spectrum and potent antifungal activity. Luliconazole can be used for the research of skin infection, including?dermatophytosis, tinea corporis, tinea pedis?et al .
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- HY-W010611R
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Bacterial
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Infection
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Lasalocid (Standard) is the analytical standard of Lasalocid. This product is intended for research and analytical applications. Lasalocid (Lasalocid-A; Ionophore X-537A; Antibiotic X-537A) is an antibacterial and anticoccidial agent used in feed additives.
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- HY-B0435S
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- HY-122207R
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Antibiotic
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Infection
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Erythromycin A enol ether (Standard) is the analytical standard of Erythromycin A enol ether. This product is intended for research and analytical applications. Erythromycin A enol ether is an acidic degradation product of Erythromycin A (macrolide antibiotic) and has no antibacterial effect .
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- HY-129949
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Antibiotic
Bacterial
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Infection
Cancer
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Aztreonam (lysine) is a monocyclic beta-lactam antibiotic, and has a very high affinity for penicillin-binding protein 3 (PBP-3). Aztreonam (lysine) is active against Gram-negative aerobic bacteria .
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- HY-N6800
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- HY-15662
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Tulathromycin; CP 472295
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Antibiotic
Bacterial
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Infection
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Tulathromycin A (Tulathromycin), a macrolide antibiotic, inhibits protein synthesis (IC50=0.26 μM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects .
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- HY-Y0055R
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Antibiotic
Fungal
Bacterial
Parasite
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Infection
Neurological Disease
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Phenothiazine (Standard) is the analytical standard of Phenothiazine. This product is intended for research and analytical applications. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases .
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- HY-135577R
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Drug Metabolite
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Infection
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β-Apooxytetracycline (Standard) is the analytical standard of β-Apooxytetracycline. This product is intended for research and analytical applications. β-Apooxytetracycline is a degradation product of Oxytetracycline (HY-B0275). Oxytetracycline is a widespread antibiotic .
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- HY-19581S
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Isotope-Labeled Compounds
Antibiotic
Bacterial
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Infection
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Baquiloprim-d6 is deuterium labeled Baquiloprim. Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria[1][2].
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- HY-P2206
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Bacterial
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Infection
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Zelkovamycin is a cyclic peptide antibiotic originally isolated from Streptomyces. It inhibits growth of X. oryzae, P. oryzae, S. aureus, and A. laidlawii in a concentration-dependent manner when used at concentrations ranging from 0.01 to 300 μg/mL.
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- HY-B0186A
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Bacterial
Antibiotic
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Infection
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Cefoselis hydrochloride, the fourth gen-eration of cephalosporin, is a β-lactam antibiotic. Cefoselis hydrochloride exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis hydrochloride penetrates the blood-brain barrier .
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- HY-P1687
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Bacterial
Apoptosis
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Cancer
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Siomycin A is a thiopeptide antibiotic and is a Forkhead box M1(FOXM1) selective inhibitor without affecting other members of the Forkhead box family. Siomycin A has anti-tumor and promotes apoptosis .
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- HY-B0213S1
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Sulfametoxydiazine-13C6; 5-Methoxysulfadiazine-13C6
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Isotope-Labeled Compounds
Antibiotic
Bacterial
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Infection
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Sulfameter- 13C6 is the 13C6 labeled Sulfameter. Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis.
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- HY-108279R
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Antibiotic
Bacterial
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Infection
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Ulifloxacin (Standard) is the analytical standard of Ulifloxacin. This product is intended for research and analytical applications. Ulifloxacin is a broad-spectrum quinolone antibiotic. Ulifloxacin is the active metabolite of Prulifloxacin (HY-B0024). Ulifloxacin has anti-bacterial activity .
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- HY-N6782
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- HY-P1872
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Bacterial
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Infection
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OV-1, sheep is an alpha-helical antimicrobial ovispirin peptide derived from SMAP29 peptide (sheep), which inhibits several antibiotic-resistant bacterial strains including mucoid and nonmucoid Pseudomonas aeruginosa .
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- HY-N5158B
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Antibiotic
Endogenous Metabolite
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Infection
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(5S)-Neosamine C is an aminocyclic alcohol antibiotic derived from microbial secondary metabolites. (5S)-Neosamine C has a cyclized structure and can be used for biosynthesis of Neomycins (HY-B0470).
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- HY-124439
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Antibiotic
Bacterial
SARS-CoV
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Infection
Cancer
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Setomimycin is a potent antibiotic. Setomimycin inhibits the SARS-CoV-2 Mpro enzyme with an IC50 value of 12.02 µM. Setomimycin shows anti-inflammatory and antioxidant properties. Setomimycin shows antiproliferative and antitumor activity .
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- HY-112176
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Fungal
Bacterial
Antibiotic
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Infection
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Kanosamine hydrochloride is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain fungi and a few bacterial species. Kanosamine inhibits Phytophthora medicaginis M2913 and Aphanomyces euteiches WI-98 with MICs of 25 and 60 μg/mL, respectively.
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- HY-N7139BR
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Bacterial
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Infection
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Penicillin G benzathine (tetrahydrate) (Standard) is the analytical standard of Penicillin G benzathine (tetrahydrate). This product is intended for research and analytical applications. Penicillin G benzathine tetrahydrate (Benzathine benzylpenicillin tetrahydrate) is an antibiotic against many bacterial infections .
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- HY-16742B
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Antibiotic
Bacterial
Topoisomerase
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Infection
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Gepotidacin mesylate hydrate is an orally active triazaacenaphthylene antibiotic and bacterial type II topoisomerase inhibitor. Gepotidacin mesylate hydrate inhibits bacterial DNA replication by blocking topoisomerase enzymes. Gepotidacin mesylate hydrate selectively inhibits topoisomerase IV and the B subunit of DNA gyrase .
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- HY-W051723
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(R)-(-)-3-Hydroxybutanoic acid; (R)-3-Hydroxybutyric acid
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Endogenous Metabolite
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Metabolic Disease
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(R)-3-Hydroxybutanoic acid is a metabolite, and converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid has applications as a nutrition source and as a precursor for vitamins, antibiotics and pheromones .
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- HY-B0272R
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Rifampin (Standard); Rifamycin AMP (Standard)
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Bacterial
Influenza Virus
Antibiotic
Orthopoxvirus
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Infection
Cancer
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Rifampicin (Standard) is the analytical standard of Rifampicin. This product is intended for research and analytical applications. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities. Rifampicin shows anti-orthopoxvirus activity.
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- HY-B0186
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Bacterial
Antibiotic
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Infection
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Cefoselis, the fourth gen-eration of cephalosporin, is a β-lactam antibiotic. Cefoselis exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis penetrates the blood-brain barrier .
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- HY-121268
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Antibiotic
Bacterial
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Infection
Inflammation/Immunology
Cancer
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Demeclocycline is an orally active tetracycline antibiotic. Demeclocycline impairs protein synthesis by binding to the 30S ribosomal subunit to inhibit binding of aminoacyl tRNA. Demeclocycline shows anti-bacterial activitise to a wide variety of bacterial infections .
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- HY-N6800A
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- HY-N6718
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Antibiotic
Fungal
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Inflammation/Immunology
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Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure .
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- HY-111320
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Bacterial
Antibiotic
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Cancer
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Chrysomycin B is an antibiotic isolated from a strain of Streptomyces. Chrysomycin B causes DNA damage in the human lung adenocarcinoma A549 cell line and inhibits topoisomerase II. Chrysomycin B suppresses the growth of transplantable tumors in mice.
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- HY-135212S
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Endogenous Metabolite
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Metabolic Disease
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Hydroxy ipronidazole-d3 is the deuterium labeled Hydroxy ipronidazole. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound[1].
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- HY-111402
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