Search Result

Pathways Recommended:	Antibody-drug Conjugate/ADC Related
Targets Recommended:	ADC Linker PROTAC-linker Conjugate for PAC

Results for "Antibody Samplers Inhibitors" in MCE Product Catalog:

By Targets:	ADC Linker (567) PROTAC-linker Conjugate for PAC (1) ADC Cytotoxin (32) Amyloid-β (1) Antibiotic (3) Apoptosis (5) Autophagy (2) Bacterial (6) Bcr-Abl (1) CaMK (1) Casein Kinase (1) DNA Alkylator/Crosslinker (12) DNA/RNA Synthesis (1) Drug-Linker Conjugates for ADC (30) DYRK (2) EGFR (3) Endogenous Metabolite (1) Ephrin Receptor (1) Epigenetic Reader Domain (2) Estrogen Receptor/ERR (3) Factor Xa (1) GLUT (1) HIV (1) HSV (2) Influenza Virus (3) Integrin (2) Interleukin Related (6) Microtubule/Tubulin (14) Mitochondrial Metabolism (1) MMP (1) Nampt (2) Neurokinin Receptor (1) p38 MAPK (1) PD-1/PD-L1 (5) Phosphatase (2) PKA (1) PKC (1) PROTAC (4) PROTAC Linker (52) Reverse Transcriptase (1) SARS-CoV (8) Sodium Channel (1) Thrombin (1) TNF Receptor (2) Toll-like Receptor (TLR) (2) Topoisomerase (1) TSH Receptor (1) VEGFR (2)
By Research Areas:	Cancer (660) Cardiovascular Disease (4) Endocrinology (1) Infection (19) Inflammation/Immunology (50) Metabolic Disease (3) Neurological Disease (4)

By Targets:

ADC Linker (567)

PROTAC-linker Conjugate for PAC (1)

ADC Cytotoxin (32)

Amyloid-β (1)

Antibiotic (3)

Apoptosis (5)

Autophagy (2)

Bacterial (6)

Bcr-Abl (1)

CaMK (1)

Casein Kinase (1)

DNA Alkylator/Crosslinker (12)

DNA/RNA Synthesis (1)

Drug-Linker Conjugates for ADC (30)

DYRK (2)

EGFR (3)

Endogenous Metabolite (1)

Ephrin Receptor (1)

Epigenetic Reader Domain (2)

Estrogen Receptor/ERR (3)

Factor Xa (1)

GLUT (1)

HIV (1)

HSV (2)

Influenza Virus (3)

Integrin (2)

Interleukin Related (6)

Microtubule/Tubulin (14)

Mitochondrial Metabolism (1)

MMP (1)

Nampt (2)

Neurokinin Receptor (1)

p38 MAPK (1)

PD-1/PD-L1 (5)

Phosphatase (2)

PKA (1)

PKC (1)

PROTAC (4)

PROTAC Linker (52)

Reverse Transcriptase (1)

SARS-CoV (8)

Sodium Channel (1)

Thrombin (1)

TNF Receptor (2)

Toll-like Receptor (TLR) (2)

Topoisomerase (1)

TSH Receptor (1)

VEGFR (2)

By Research Areas:

Cancer (660)

Cardiovascular Disease (4)

Endocrinology (1)

Infection (19)

Inflammation/Immunology (50)

Metabolic Disease (3)

Neurological Disease (4)

706

Inhibitors & Agonists

Screening Libraries

Dye Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas

HY-P9917

Tocilizumab Anti-Human IL6R, Humanized Antibody	Interleukin Related	Cancer Inflammation/Immunology
Tocilizumab (Anti-Human IL6R, Humanized Antibody) is an anti-human interleukin-6 receptor (IL-6R) neutralizing antibody, prevents binding of IL-6 to the IL-6R, thereby inhibiting both classic and trans-signaling. Tocilizumab (Anti-Human IL6R, Humanized Antibody) can be used for the treatment of rheumatoid arthritis. Tocilizumab is remarkablely effective for the study of severe COVID-19 (coronavirus disease).

HY-P9803

Anti-SARS-80R mAb SARS-80R; SARS Antibody-80R	SARS-CoV	Infection
Anti-SARS-80R mAb (SARS-80R) is a human monoclonal IgG1 antibody produced in CHO cells. Anti-SARS-80R mAb can specifically bind to Spike (S1) protein to prevent SARS virus infection of susceptible cells.

HY-P9801

Anti-Spike-RBD mAb SARS-CoV-2 (2019-nCoV) Spike RBD Antibody	SARS-CoV	Infection
Anti-Spike-RBD mAb is a CHO cell derived human monoclonal IgG1 antibody. Blocking the interaction of spike protein and ACE2 is a potential therapeutic approach for SARS-CoV-2 treatment.

HY-P9807

Anti-SARS-CoV-2 Spike mAb (CR3022) SARS-CR3022; SARS-CoV-2 Antibody-CR3022	SARS-CoV	Infection Inflammation/Immunology
Anti-SARS-CoV-2 Spike mAb (CR3022) is a a CHO cell derived human monoclonal IgG1 antibody. It binds to both S1 domain of SARS-CoV/SARS-CoV-2 Spike protein.

HY-P9805

Anti-MERS-3A1 mAb MERS-3A1; MERS Antibody-3A1	SARS-CoV	Infection
Anti-MERS-3A1 mAb (MERS-3A1) is a human monoclonal IgG1 antibody with the high binding affinity produced in CHO cells. Anti-MERS-3A1 mAb bocks the binding of MERS-CoV spike protein to DPP4 receptor.

HY-P9802

Anti-Spike-RBD Single Domain mAb SARS-CoV-2 (2019-nCoV) Single-Domain Antibodies; Humanized Single Domain Antibody	SARS-CoV	Infection
Anti-Spike-RBD Single Domain mAb is a CHO cell derived Alpaca monoclonal VHH-huFc antibody, specifically binds to SARS-CoV-2 RBD with high affinity.

HY-P9916

Sarilumab Anti-Human IL6Rα, Human Antibody	Interleukin Related	Inflammation/Immunology
Sarilumab (Anti-Human IL6Rα, Human Antibody) is a human immunoglobulin G1 monoclonal antibody. Sarilumab, a interleukin-6 (IL-6) receptor antagonist, binds to the IL-6 receptor with high affinity and inhibits cis and trans signaling by IL-6, resulting in reduced inflammation. Sarilumab can be used for the research of Rheumatoid arthritis.

HY-P9906

Bevacizumab
Anti-Human VEGF, Humanized Antibody
VEGFR Cancer

Bevacizumab, a humanized monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity.
HY-P9908

Adalimumab
Anti-Human TNF-alpha, Human Antibody
TNF Receptor Inflammation/Immunology

Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).
HY-P9909

Ustekinumab
Anti-Human IL-12/IL-23, Human Antibody
Interleukin Related Inflammation/Immunology

Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.

Bevacizumab Anti-Human VEGF, Humanized Antibody	VEGFR	Cancer
Bevacizumab, a humanized monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity.

Adalimumab Anti-Human TNF-alpha, Human Antibody	TNF Receptor	Inflammation/Immunology
Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).

Ustekinumab Anti-Human IL-12/IL-23, Human Antibody	Interleukin Related	Inflammation/Immunology
Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.

HY-P9907

Trastuzumab Anti-Human HER2, Humanized Antibody	EGFR	Cancer
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has the potential for HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer research.

HY-108730

Avelumab Anti-Human PD-L1, Human Antibody; MSB 0010718C; MSB0010718C	PD-1/PD-L1	Cancer Inflammation/Immunology
Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity.

HY-P9911

Vedolizumab Anti-Human lymphocyte α4β7 integrin, Humanized Antibody	Integrin	Inflammation/Immunology
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease.

HY-P9804

Anti-MERS-2E6 mAb MERS-2E6; MERS Antibody-2E6	SARS-CoV	Infection
Anti-MERS-2E6 mAb (MERS-2E6; MERS Antibody-2E6), a human neutralizing antibody IgG1 (CHO expressed) that can compete for the binding of the virus Spike protein to the receptor (CD26), thereby inhibiting virus invasion into host cells.

HY-U00439

Protein kinase inhibitors 1
DYRK Cancer

Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC₅₀ of 74 nM and K_d of 9.5 nM.
HY-131326

DOTA-tris(tBu)ester NHS ester
Others Cancer

DOTA-tris(tBu)ester NHS ester is a derivative of DOTA for the labeling of peptides and antibodies.

*Protein kinase inhibitors* 1**	DYRK	Cancer
Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC₅₀ of 74 nM and K_d of 9.5 nM.

DOTA-tris(tBu)ester NHS ester	Others	Cancer
DOTA-tris(tBu)ester NHS ester is a derivative of DOTA for the labeling of peptides and antibodies.

HY-P9806

Anti-MERS-D12 mAb MERS-D12; MERS Antibody-D12	SARS-CoV	Infection
Anti-MERS-D12 mAb (MERS-D12; MERS Antibody-D12) is a human monoclonal IgG1. Anti-MERS-D12 mAb binds directly to the DPP4 interacting region of the MERS-CoV Spike receptor binding domain (RBD) and effect neutralization by directly blocking receptor binding.

HY-118870

γ-Globulins from human blood	Endogenous Metabolite	Inflammation/Immunology
γ-Globulins from human blood are a class of proteins in the blood. γ-Globulin is a protein fraction of blood serum containing many antibodies that protect against bacterial and viral infectious diseases. γ-Globulins from human blood is used for common variable immunodeficiency

HY-18286

NCGC00229600	TSH Receptor	Endocrinology
NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR). NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously expressed in Graves' disease.

HY-15583

Auristatin F	Microtubule/Tubulin ADC Cytotoxin	Cancer
Auristatin F is a potent cytotoxin. Auristatin F, a potent microtubule inhibitor and vascular damaging agent (VDA), can be used in antibody-drug conjugates (ADC).

HY-N3522

Platycoside E	Others	Inflammation/Immunology
Platycoside E is a platycodigenin-type saponin isolated from the root of Platycodon grandiflorum with haemolytic activity and adjuvant potential. Platycoside E promotes the production of the sera OVA-specific IgG2a and IgG2b antibody in the ovalbumin (OVA)-immunized mice.

HY-W019939

Hydroxy-PEG10-Boc	ADC Linker	Cancer
Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024). Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel (HY-B0015) or docetaxel (HY-B0011).

HY-131005

Ehp inhibitor 2
Ephrin Receptor Cancer

Ehp inhibitor 2 is a Eph family tyrosine kinase inhibitor.
HY-P9902

Pembrolizumab
MK-3475; Lambrolizumab
PD-1/PD-L1 Cancer

Pembrolizumab is a humanized antibody inhibiting the programmed cell death 1 (PD-1) receptor, used in cancer immunotherapy.

Ehp inhibitor 2	Ephrin Receptor	Cancer
Ehp inhibitor 2 is a Eph family tyrosine kinase inhibitor.

Pembrolizumab MK-3475; Lambrolizumab	PD-1/PD-L1	Cancer
Pembrolizumab is a humanized antibody inhibiting the programmed cell death 1 (PD-1) receptor, used in cancer immunotherapy.

HY-P9923

Benralizumab MEDI-563; BIW-8405	Interleukin Related	Inflammation/Immunology
Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma.

HY-P9919

Durvalumab MEDI 4736	PD-1/PD-L1	Cancer
Durvalumab (MEDI 4736) is an humanized anti-PD-L1 monoclonal antibody. Durvalumab (MEDI4736) completely blocks the binding of PD-L1 to both PD-1 and CD80, with IC₅₀s of 0.1 and 0.04 nM, respectively.

HY-P9912

Pertuzumab
EGFR Cancer

Pertuzumab, a humanized monoclonal antibody, is a HER2 dimerization inhibitor for the treatment of metastatic HER2-positive breast cancer.
HY-121879

SHP836
Phosphatase Cancer

SHP836 is a SHP2 allosteric inhibitor, with an IC₅₀ of 12 μM for the full length SHP2.
HY-P9904

Atezolizumab
MPDL3280A
PD-1/PD-L1 Cancer

Atezolizumab is a selective humanized monoclonal IgG1 antibody against programmed death ligand 1 (PD-L1), used for cancer research.
HY-P9903

Nivolumab
BMS-936558; ONO-4538; MDX-1106
PD-1/PD-L1 Cancer

Nivolumab is a programmed death receptor-1 (PD-1) blocking antibody to treat advanced (metastatic) non-small cell lung cancer.

Pertuzumab	EGFR	Cancer
Pertuzumab, a humanized monoclonal antibody, is a HER2 dimerization inhibitor for the treatment of metastatic HER2-positive breast cancer.

SHP836	Phosphatase	Cancer
SHP836 is a SHP2 allosteric inhibitor, with an IC₅₀ of 12 μM for the full length SHP2.

Atezolizumab MPDL3280A	PD-1/PD-L1	Cancer
Atezolizumab is a selective humanized monoclonal IgG1 antibody against programmed death ligand 1 (PD-L1), used for cancer research.

Nivolumab BMS-936558; ONO-4538; MDX-1106	PD-1/PD-L1	Cancer
Nivolumab is a programmed death receptor-1 (PD-1) blocking antibody to treat advanced (metastatic) non-small cell lung cancer.

HY-P9905

Cetuximab C225	EGFR	Cancer
Cetuximab (C225) is a monoclonal antibody that inhibits epidermal growth factor receptor (EGFR), with a K_d of 0.201 nM for soluble EGFR by SPR. Cetuximab has potent antitumor activity.

HY-19373

RWJ-445167 3DP-10017	Thrombin Factor Xa	Cardiovascular Disease
RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with K_i of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity.

HY-16787

ICA-121431	Sodium Channel	Cardiovascular Disease
ICA-121431 is a nanomolar potent and broad-spectrum voltage-gated sodium channel (Na_v) blocker, shows equipotent selectivity for human Na_v1.1 and Na_v1.3 subtypes with IC₅₀ values of 13 nM and 23 nM, respectively. ICA-121431 shows less potent inhibition of Na_v1.2 (IC₅₀=240 nM) and 1,000 fold selectivity against Na_v1.4, Na_v1.6, and the TTX-resistant human Na_v1.5 and Na_v1.8 channels (IC₅₀s >10 µM).

HY-U00439A

*Protein kinase inhibitors* 1 hydrochloride** (E)-5-((2-Oxo-6'-(piperazin-1-yl)-1,2-dihydro-[3,3'-bipyridin]-5-yl)methylene)thiazolidine-2,4-dione hydrochloride	DYRK	Cancer
Protein kinase inhibitors 1 hydrochloride is a potent HIPK2 inhibitor, with IC₅₀s of 136 and 74 nM for HIPK1 and HIPK2, and a K_d of 9.5 nM for HIPK2.

HY-P1783A

M2e, human TFA	Influenza Virus	Infection
M2e, human TFA, consisting of the 23 extracellular residues of M2 (the third integral membrane protein of influenza A), has been remarkably conserved in all human influenza A. M2e, human TFA is a valid and versatile vaccine candidate to protect against any strain of human influenza A.

HY-135682

Nitrosobiotin
Others Others

Nitrosobiotin is prepared from biotin.

Nitrosobiotin	Others	Others
Nitrosobiotin is prepared from biotin.

HY-P1783

M2e, human	Influenza Virus	Infection
M2e, human, consisting of the 23 extracellular residues of M2 (the third integral membrane protein of influenza A), has been remarkably conserved in all human influenza A, which is a valid and versatile vaccine candidate to protect against any strain of human influenza A.

HY-P9970

Infliximab Avakine; CT-P13	TNF Receptor	Metabolic Disease Inflammation/Immunology Neurological Disease
Infliximab (Avakine) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α. Infliximab has the potential for autoimmune, chronic inflammatory diseases and diabetic neuropathy research.

HY-W012037

8-Hydroxyquinoline hemisulfate 8-Quinolinol hemisulfate	Bacterial Antibiotic	Infection
8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.

HY-135813

LtaS-IN-1	Bacterial	Infection
LtaS-IN-1 (compound 1771) is a potent small-molecule inhibitor of Lipoteichoic acid (LTA) synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 alone inhibits Enterococcus.spp 28 strains with varying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 combination with antibiotics abolishs multidrug-resistant E. faecium growth almost completely.

HY-125957

A-3 hydrochloride	PKA Casein Kinase CaMK PKC	Others
A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It against PKA (K_i=4.3 µM), casein kinase II (K_i=5.1 µM) and myosin light chain kinase (MLCK) (K_i=7.4 µM). A-3 hydrochloride also inhibits PKC and casein kinase I with K_i values of 47 µM and 80 µM, respectively.

HY-108831

Natalizumab	Integrin	Inflammation/Immunology
Natalizumab is a recombinant, humanized monoclonal antibody, binds to α4β1-integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1). Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses.

HY-P9920

Ramucirumab	VEGFR	Cancer
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D.

HY-P9949

Reslizumab Sch 55700	Interleukin Related	Inflammation/Immunology
Reslizumab (Sch 55700) is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. Reslizumab is effective in neutralizing the function of IL-5. Reslizumab inhibits IL-5-dependent cell proliferation, with an IC₅₀ value of approximately 91.1pM. Reslizumab has high binding affinity for human IL-5, with K_D values of 109 pM and 4.3 pM in the the Biacore surface plasmon resonance and Kinetic Exclusion Assay, respectively.

HY-101918

DS-1040 Tosylate	Others	Cardiovascular Disease
DS-1040 Tosylate is an orally active, selective inhibitor of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC₅₀s of 5.92 nM and 8.01 nM for human and rat TAFIa. DS-1040 Tosylate is a fibrinolysis enhancer for thromboembolic diseases.

HY-18728

STF-31
GLUT Autophagy Cancer

STF-31 is a selective inhibitor of glucose transporter 1 (GLUT1), with an IC₅₀ of 1μM^[1][2].

STF-31	GLUT Autophagy	Cancer
STF-31 is a selective inhibitor of glucose transporter 1 (GLUT1), with an IC₅₀ of 1μM^[1][2].

HY-19792

Mertansine DM1; Maytansinoid DM1	Microtubule/Tubulin ADC Cytotoxin	Cancer
Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC).

HY-102090

B7/CD28 interaction inhibitor 1
Others Inflammation/Immunology

B7/CD28 interaction inhibitor 1 is a potent B7.1-CD28 interaction inhibitor with an IC₅₀ of 50 nM.

HY-122470

Stampidine	Reverse Transcriptase HIV	Infection
Stampidine is a nucleoside reverse transcriptase inhibitor (NRTI) with potent and broad-spectrum anti-HIV activity. Stampidine inhibits the laboratory HIV-1 strain HTLV_IIIB (B-envelope subtype) and primary clinical isolates with IC₅₀s of 1 nM and 2 nM, respectively. Stampidine also inhibits NRTI-resistant primary clinical isolates and NNRTI-resistant clinical isolates with IC₅₀s of 8.7 nM and 11.2 nM, respectively.

HY-130082

DM4-SMe	ADC Cytotoxin Microtubule/Tubulin	Cancer
DM4-SMe is a metabolite of antibody-maytansin conjugates (AMCs) and a tubulin inhibitor, and also a cytotoxic moiety of antibody-drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond. DM4-SMe inhibits KB cells with an IC₅₀ of 0.026 nM.

HY-15581

MMAD Demethyldolastatin 10; Monomethylauristatin D; Monomethyl Dolastatin 10	Microtubule/Tubulin ADC Cytotoxin	Cancer
MMAD is a potent tubulin inhibitor, is a toxin payload in antibody drug conjugates (ADCs).

HY-130107

Ald-Ph-NHS ester
ADC Linker Cancer

Ald-Ph-NHS ester is a nonclaevable linker for antibody-drug-conjugation (ADC).
HY-129365

SNPB
ADC Linker Cancer

SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).

HY-112100

PAC	Estrogen Receptor/ERR PROTAC-linker Conjugate for PAC	Cancer
PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).

HY-11007

GNF-2
Bcr-Abl SARS-CoV Cancer

GNF-2 is a highly selective, allosteric, non-ATP competitive inhibitor of Bcr-Abl. GNF-2 inhibits Ba/F3.p210 proliferation with an IC₅₀ of 138 nM .
HY-42146

BMPS
ADC Linker Cancer

BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129376

Sulfo-SNPB
ADC Linker Cancer

Sulfo-SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).
HY-19318

Fmoc-Val-Cit-PAB
ADC Linker Cancer

Fmoc-Val-Cit-PAB is a cleavable linker for antibody-drug-conjugation (ADC).

HY-19839

Ansamitocin P 3' Antibiotic C 15003P3'; Maytansinol butyrate	ADC Cytotoxin Microtubule/Tubulin	Cancer
Ansamitocin P 3' exhibits antitumour activity, is an antibody drug conjugate cytotoxin.

HY-126519

PDdEC-NB
ADC Linker Cancer

PDdEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).
HY-129366

PDB-Pfp
ADC Linker Cancer

PDB-Pfp is a reducible ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129375

SNPB-sulfo-Me
ADC Linker Cancer

SNPB-sulfo-Me is a cleavable linker that is used for making antibody-drug conjugate (ADC).
HY-44235

MC-Gly-Gly-Phe
ADC Linker Cancer

MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).
HY-129373

SPDMV-sulfo
ADC Linker Cancer

SPDMV-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).
HY-126667

SC-Val-Cit-PAB
ADC Linker Cancer

SC-Val-Cit-PAB is a cleavable ADC linker for antibody-drug conjugates (ADCs).
HY-126498

PDEC-NB
ADC Linker Cancer

PDEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).
HY-129369

SPDMB
ADC Linker Cancer

SPDMB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).
HY-12448

SPDB
ADC Linker Cancer

SPDB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).
HY-129368

SPDMV
ADC Linker Cancer

SPDMV is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).
HY-126511

Propargyl-C1-NHS ester
ADC Linker Cancer

Propargyl-C1-NHS ester is a nonclaevable linker for antibody-drug-conjugation (ADC).
HY-126530

PPC-NB
ADC Linker Cancer Cardiovascular Disease

PPC-NB is a glutathione cleavable linker used for the antibody-drug conjugate (ADC).
HY-133540

Maleimide-DOTA
Maleimido-mono-amide-DOTA
ADC Linker Cancer Inflammation/Immunology

Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126518

Cyclooctyne-O-PFP ester
ADC Cytotoxin Cancer

Cyclooctyne-O-PFP ester is a used as an ADC cytotoxin, which connects antibody and linker.
HY-126512

Propargyl-C2-NHS ester
ADC Linker Cancer

Propargyl-C2-NHS ester is a nonclaevable linker for antibody-drug-conjugation (ADC).
HY-129370

SPDB-sulfo
ADC Linker Cancer

SPDB-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .
HY-128927

Mc-Leu-Gly-Arg
ADC Linker Cancer

Mc-Leu-Gly-Arg is a cleavable ether linker for antibody-drug conjugates (ADC) design.

HY-78961

6-Maleimidohexanoic acid N-hydroxysuccinimide ester EMCS	ADC Linker	Cancer
6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates.

HY-17422

Acyclovir Aciclovir; Acycloguanosine	HSV Bacterial Antibiotic Apoptosis	Cancer Infection
Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC₅₀ of 0.85 μM), HSV-2 (IC₅₀ of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia.

HY-136095

Tetrazine-biotin
ADC Linker Cancer

Tetrazine-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130111

DMAC-SPP
ADC Linker Cancer

DMAC-SPP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-41919

Mal-L-PA-NH-Boc
mDPR(boc)
ADC Linker Cancer

Mal-L-PA-NH-Boc is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140014

Val-Cit
ADC Linker Cancer

Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-101151

sulfo-SPDB
ADC Linker Cancer

sulfo-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-128970

Mp-polymer ester
ADC Linker Cancer

Mp-polymer ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-116270

DBCO-Maleimide
ADC Linker Cancer

DBCO-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126349

DTSSP Crosslinker
ADC Linker Cancer

DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140098

Boc-Cystamine
ADC Linker Cancer

Boc-Cystamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129353

Boc-Phe-(Alloc)Lys-PAB-PNP
ADC Linker Cancer

Boc-Phe-(Alloc)Lys-PAB-PNP is a used as a cleavable linker for antibody-drug conjugates (ADC).
HY-126496

PEG4-SPDP
ADC Linker Cancer

PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
HY-129367

NO2-SPP
ADC Linker Cancer

NO2-SPP is a cleavable linker that is used for making antibody-drug conjugate (ADC).
HY-118759

DSP Crosslinker
ADC Linker Inflammation/Immunology

DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs).
HY-42973

DBCO-NHS ester
ADC Linker Cancer

DBCO-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133550

DMAC-SPDB
ADC Linker Cancer

DMAC-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126405

SMPT
ADC Linker Cancer

SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129352

Cbz-Phe-(Alloc)Lys-PAB-PNP
ADC Linker Cancer

Cbz-Phe-(Alloc)Lys-PAB-PNP is an cleavable linker for antibody-drug conjugates (ADC) design.
HY-133542

Dimethylamine-SPDB
ADC Linker Cancer

Dimethylamine-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-117050

PEG12-Tos
ADC Linker Cancer

Tos-PEG12 is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-U00265

3-CPs
3-Carbethoxypsoralen; 3-Ethoxycarbonylpsoralen
Others Infection

3-CPs is a serotype capsular polysaccharide which can interfere with antibody-mediated bacterial killing.
HY-126531

DMAC-PDB
ADC Linker Cancer

DMAC-PDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136104

Methyltetrazine-Maleimide
ADC Linker Cancer

Methyltetrazine-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W000423

DBCO-amine
ADC Linker Cancer

DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W071006

PPC-NHS ester 2,5-Dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate	ADC Linker	Cancer
PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133543

SPDP-sulfo
ADC Linker Cancer

SPDP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-20560

(Ac)Phe-Lys(Alloc)-PABC-PNP
ADC Linker Cancer

(Ac)Phe-Lys(Alloc)-PABC-PNP is an useful cleavable chemical linker in antibody drug conjugates.
HY-114697

DSG Crosslinker
ADC Linker Inflammation/Immunology

DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136033

Methyltetrazine-SS-NHS
ADC Linker Cancer

Methyltetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140987

5-Maleimidovaleric acid
ADC Linker Cancer

5-Maleimidovaleric acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140313

Methyltetrazine-DBCO
ADC Linker Cancer

Methyltetrazine-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130110

Sulfo-DMAC-SPP
ADC Linker Cancer

Sulfo-DMAC-SPP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140306

Mal-Sulfo-DBCO
ADC Linker Cancer

Mal-Sulfo-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W019543

DSS Crosslinker
ADC Linker Cancer

DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-23641

NH-bis(C1-Boc)
ADC Linker Cancer

NH-bis(C1-Boc)is a uncleavable linker used for antibody-drug conjugates (ADC).
HY-140105

Azidoethyl-SS-ethylazide
ADC Linker Cancer

Azidoethyl-SS-ethylazide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141158

N-(Iodoacetamido)-Doxorubicin
ADC Linker Cancer

N-(Iodoacetamido)-Doxorubicin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136031

Tetrazine-SS-Biotin
ADC Linker Cancer

Tetrazine-SS-Biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140100

Azidoethyl-SS-propionic acid
ADC Linker Cancer

Azidoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140296

BDP FL DBCO
ADC Linker Cancer

BDP FL DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130099

Ald-Ph-amido-PEG2
ADC Linker Cancer

Ald-Ph-amido-PEG2 is a noncleavable ADC linker for antibody-drug conjugate.
HY-135973

BCN-SS-NHS
ADC Linker Cancer

BCN-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136032

Tetrazine-SS-NHS
ADC Linker Cancer

Tetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135978

DBCO-SS-amine
ADC Linker Cancer

DBCO-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135972

BCN-SS-amine
ADC Linker Cancer

BCN-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-41189

Fmoc-Val-Cit-PAB-PNP
ADC Linker Cancer

Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140096

Aminoethyl-SS-propionic acid
ADC Linker Cancer

Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126851

Fluorescein-DBCO
ADC Linker Cancer

Fluorescein-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130928

Tetrazine-Ph-OPSS
ADC Linker Cancer

Tetrazine-Ph-OPSS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-116063

Doxorubicin-SMCC
ADC Linker Cancer

Doxorubicin-SMCC is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-128929

Fmoc-PEA
ADC Linker Cancer

Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC).
HY-44221

MAC glucuronide linker-1
ADC Linker Cancer

MAC glucuronide linker-1 is a nonclaevable ADC linker for antibody-drug-conjugations (ADCs).
HY-140122

THP-SS-alcohol
ADC Linker Cancer

THP-SS-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135418

Fmoc-Asp-NH2
ADC Linker Cancer

Fmoc-Asp-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-123687

DBCO-Sulfo-NHS ester sodium
ADC Linker Cancer

DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140104

Azidoethyl-SS-ethylamine
ADC Linker Cancer

Azidoethyl-SS-ethylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129360

Ala-Ala-Asn-PAB
ADC Linker Cancer

Ala-Ala-Asn-PAB is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs).
HY-135977

DBCO-SS-aldehyde
ADC Linker Cancer

DBCO-SS-aldehyde is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-131084

DMAC-SPDB-sulfo
ADC Linker Cancer

DMAC-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-12454

DM4
Microtubule/Tubulin Cancer

DM4 is is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody drug conjugate.
HY-W011541

SIA Crosslinker
ADC Linker Cancer

SIA Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W002213

N-Hydroxysulfosuccinimide sodium
ADC Linker Cancer

N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140129

NHS-SS-biotin
ADC Linker Cancer

NHS-SS-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W044078

N-Boc-diethanolamine
ADC Linker Cancer

N-Boc-diethanolamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136039

TCO-SS-amine
ADC Linker Cancer

TCO-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128527

PROTAC ER Degrader-3	PROTAC Estrogen Receptor/ERR	Cancer
PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).

HY-128528

PROTAC ER Degrader-2	PROTAC Estrogen Receptor/ERR	Cancer
PROTAC ER Degrader-2 is an intermediate for synthesis of PAC. PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).

HY-130081

DM3-SMe	ADC Cytotoxin Microtubule/Tubulin	Cancer
DM3-SMe is a maytansine derivative and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond. DM3-SMe shows highly cytotoxic activity in vitro with an IC₅₀ of 0.0011 nM.

HY-136138

MC-VC-PAB-Azide
ADC Linker Cancer

MC-VC-PAB-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130112

N-Succinimidyloxycarbonylpropyl methanethiosulfonate NHS-C4-MTS	ADC Linker	Cancer
N-Succinimidyloxycarbonylpropyl methanethiosulfonate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-124329

BS3 Crosslinker
ADC Linker Cancer

BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130935

DBCO-Val-Cit-OH
ADC Linker Cancer

DBCO-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-101153

MC-Val-Ala-OH
ADC Linker Cancer

MC-Val-Ala-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126364

Mc-Val-Ala-PAB
ADC Linker Cancer

Mc-Val-Ala-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140138

PC SPDP-NHS carbonate ester
ADC Linker Cancer

PC SPDP-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-20336

Mc-Val-Cit-PABC-PNP Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate	ADC Linker	Cancer
Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136102

Py-ds-Prp-Osu
ADC Linker Cancer

Py-ds-Prp-Osu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140102

Azidoethyl-SS-propionic NHS ester
ADC Linker Cancer

Azidoethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W023121

Fmoc-Gly-Gly-OH
ADC Linker Cancer

Fmoc-Gly-Gly-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141141

Boc-Val-Cit-PAB
ADC Linker Cancer

Boc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126524

N3-Ph-NHS ester
ADC Linker Cancer

N3-Ph-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140140

PC Mal-NHS carbonate ester
ADC Linker Cancer

PC Mal-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130810

DBCO-Sulfo-Link-biotin
ADC Linker Cancer

DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129362

Phe-Lys(Fmoc)-PAB
ADC Linker Cancer

Phe-Lys(Fmoc)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs).
HY-42745

m-PEG2-Tos
ADC Linker Cancer

m-PEG2-Tos is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129349

Phe-Lys(Trt)-PAB
ADC Linker Cancer

Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs).
HY-78738

MC-Val-Cit-PAB
ADC Linker Cancer

MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate.
HY-W038702

Boc-Val-Cit-OH
ADC Linker Cancer

Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133504

Tetrazine-Ph-SS-amine
ADC Linker Cancer

Tetrazine-Ph-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-114430

Fmoc-Phe-Lys(Boc)-PAB-PNP
ADC Linker Others

Fmoc-Phe-Lys(Boc)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126353

Fmoc-Val-Ala-PAB-OH
ADC Linker Cancer

Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-44234

Fmoc-Gly-Gly-Phe-OtBu
ADC Linker Cancer

Fmoc-Gly-Gly-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130089

Bis-PEG1-NHS ester
ADC Linker Cancer

Bis-PEG1-NHS ester is a nonclaevable 1-unit PEG linker for antibody-drug-conjugation (ADC).
HY-130090

NHPI-PEG4-C2-Pfp ester
ADC Linker Cancer

NHPI-PEG4-C2-Pfp ester is used as a linker for antibody-drug conjugates (ADC).
HY-140116

Boc-NH-ethyl-SS-propionic acid
ADC Linker Cancer

Boc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130937

DBCO-Val-Cit-PABC-PNP
ADC Linker Cancer

DBCO-Val-Cit-PABC-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-D0799

Sulfo-NHS-LC-Biotin sodium
Others Others

Sulfo-NHS-LC-Biotin sodium is a water soluble amine-reactive biotinylation reagent that can be used for antibody labeling.
HY-133412

DBCO-NHCO-S-S-NHS ester
ADC Linker Cancer

DBCO-NHCO-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130936

DBCO-Val-Cit-PABC-OH
ADC Linker Cancer

DBCO-Val-Cit-PABC-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141145

OPSS-Val-Cit-PAB-PNP
ADC Linker Cancer

OPSS-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-44222

MAC glucuronide linker-2
ADC Linker Cancer

MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130932

Boc-Val-Ala-PAB-PNP
ADC Linker Cancer

Boc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136136

Fmoc-Val-Ala-PAB-PNP
ADC Linker Cancer

Fmoc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140118

Fmoc-NH-ethyl-SS-propionic acid
ADC Linker Cancer

Fmoc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133413

DBCO-CONH-S-S-NHS ester
ADC Linker Cancer

DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126533

PDP-C1-Ph-Val-Cit
ADC Linker Cancer

PDP-C1-Ph-Val-Cit is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
HY-141144

OPSS-Val-Cit-PAB-OH
ADC Linker Cancer

OPSS-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126513

Propargyl-PEG1-NHS ester
ADC Linker Cancer

Propargyl-PEG1-NHS ester is a nonclaevable 1-unit PEG linker for antibody-drug-conjugation (ADC).
HY-126670

mDPR(Boc)-Val-Cit-PAB
ADC Linker Cancer

mDPR(Boc)-Val-Cit-PAB is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC).
HY-141142

Boc-Val-Cit-PAB-PNP
ADC Linker Cancer

Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130098

Ald-Ph-amido-PEG3-C-COOH
ADC Linker Cancer

Ald-Ph-amido-PEG3-C-COOH is a noncleavable linker used for the antibody-drug conjugate (ADC).
HY-140117

Boc-aminooxy-ethyl-SS-propanol
ADC Linker Cancer

Boc-aminooxy-ethyl-SS-propanol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130930

Acid-propionylamino-Val-Cit-OH
ADC Linker Cancer

Acid-propionylamino-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130088

Bis-PEG2-NHS ester
ADC Linker Cancer

Bis-PEG2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-drug-conjugation (ADC).
HY-140120

Mal-NH-ethyl-SS-propionic acid
ADC Linker Cancer

Mal-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140125

2-Hydroxyethyl disulfide mono-tosylate
ADC Linker Cancer

2-Hydroxyethyl disulfide mono-tosylate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136139

3-Azidopropionic Acid Sulfo-NHS ester
ADC Linker Cancer

3-Azidopropionic Acid Sulfo-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126497

LC-PEG8-SPDP
ADC Linker Cancer

LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
HY-126516

Propargyl-PEG4-NHS ester
ADC Linker Cancer

Propargyl-PEG4-NHS ester is a nonclaevable 4-unit PEG linker for antibody-drug-conjugation (ADC).
HY-W011561

Boc-NH-C6-Br
ADC Linker Cancer

Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC).
HY-136107

Fmoc-Phe-Lys(Trt)-PAB
ADC Linker Cancer

Fmoc-Phe-Lys(Trt)-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130383

Propargyl-PEG7-acid
ADC Linker Cancer

Propargyl-PEG7-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-41541

Tetraethylene glycol monotosylate Tos-PEG4	ADC Linker	Cancer
Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130386

Propargyl-PEG6-acid
ADC Linker Cancer

Propargyl-PEG6-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126663

N-Me-L-Ala-maytansinol
ADC Cytotoxin Cancer

N-Me-L-Ala-maytansinol is a hydrophobic, cell permeable payload used for making antibody-drug conjugate (ADC).
HY-136329

β-D-glucuronide-pNP-carbonate
ADC Linker Cancer

β-D-glucuronide-pNP-carbonate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130087

Bis-PEG3-NHS ester
ADC Linker Cancer

Bis-PEG3-NHS ester is a nonclaevable 3-unit PEG linker for antibody-drug-conjugation (ADC).
HY-135975

MC-Val-Ala-PAB-PNP
ADC Linker Cancer

MC-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130086

Bis-PEG4-NHS ester
ADC Linker Cancer

Bis-PEG4-NHS ester is a nonclaevable 4-unit PEG linker for antibody-drug-conjugation (ADC).
HY-W071007

NO2-SPDMV
ADC Linker Cancer

NO2-SPDMV is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126974

Propargyl-PEG3-NHS ester
ADC Linker Cancer

Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W040236

m-PEG8-Amine
ADC Linker Cancer

m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130528

m-PEG7-Ms
ADC Linker Cancer

m-PEG7-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126885

DBCO-PEG5-NHS ester
ADC Linker Cancer

DBCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133547

NO2-SPP-sulfo
ADC Linker Cancer

NO2-SPP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141170

TCO-PEG12-NHS ester
ADC Linker Cancer

TCO-PEG12-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130388

Propargyl-PEG5-NHS ester
ADC Linker Cancer

Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130408

m-PEG6-Amine
ADC Linker Cancer

m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-129356A

(S)-Seco-Duocarmycin SA	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
(S)-Seco-Duocarmycin SA is a DNA alkylator, cytotoxic to cancer cells, and acts as a ADC cytotoxin for antibody-drug conjugates.

HY-130457

m-PEG4-Ms
ADC Linker Cancer

m-PEG4-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W018174

m-PEG3-Amine
ADC Linker Cancer

m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129351

Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP
ADC Linker Cancer

Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-120237

m-PEG7-Amine
ADC Linker Cancer

m-PEG7-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133548

NO2-SPDB-sulfo
ADC Linker Cancer

NO2-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130346

DBCO-PEG4-DBCO
ADC Linker Cancer

DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-117009

Bis-PEG9-NHS ester
ADC Linker Cancer

Bis-PEG9-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136132

MC-VC-PAB-NH2
ADC Linker Cancer

MC-VC-PAB-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129350

Fmoc-Phe-Lys(Trt)-PAB-PNP
ADC Linker Cancer

Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141167

TCO-PEG4-NHS ester
ADC Linker Cancer

TCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126889

Bis-PEG5-NHS ester
ADC Linker Cancer

Bis-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-116186

m-PEG5-Ms
ADC Linker Cancer

m-PEG5-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W040222

m-PEG11-Amine
ADC Linker Cancer

m-PEG11-Amino is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W040214

m-PEG4-Amine
ADC Linker Cancer

m-PEG4-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130547

BS2G Crosslinker disodium
ADC Linker Cancer

BS2G Crosslinker (disodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129378

NO2-SPP-sulfo-Me
ADC Linker Cancer

NO2-SPP-sulfo-Me is a cleavable linker that is used for making antibody-drug conjugate (ADC).
HY-136125

BCOT-PEF3-OPFP
ADC Linker Cancer

BCOT-PEF3-OPFP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130825

Bis-PEG13-NHS ester
ADC Linker Cancer

Bis-PEG13-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130381

Propargyl-PEG7-NHS ester
ADC Linker Cancer

Propargyl-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133549

NO2-SPDMV-sulfo
ADC Linker Cancer

NO2-SPDMV-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W008429

m-PEG2-Amine
ADC Linker Cancer

m-PEG2-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140119

Fmoc-NH-ethyl-SS-propionic NHS ester
ADC Linker Cancer

Fmoc-NH-ethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130827

Bis-PEG21-NHS ester
ADC Linker Cancer

Bis-PEG21-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140310

TCO-PEG4-DBCO
ADC Linker Cancer

TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130166

Amino-PEG9-acid
ADC Linker Cancer

Amino-PEG9-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-120770

DBCO-PEG4-Maleimide
ADC Linker Cancer

DBCO-PEG4-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130385

Propargyl-PEG6-NHS ester
ADC Linker Cancer

Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126886

Mal-PEG1-NHS ester
ADC Linker Cancer

Mal-PEG1-NHS ester is a cleavable and PEG-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130571

m-PEG9-Amine
ADC Linker Cancer

m-PEG9-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130933

Fmoc-Ala-Ala-Asn(Trt)-OH
ADC Linker Cancer

Fmoc-Ala-Ala-Asn(Trt)-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130826

Bis-PEG17-NHS ester
ADC Linker Cancer

Bis-PEG17-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130828

Bis-PEG25-NHS ester
ADC Linker Cancer

Bis-PEG25-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126502

Mal-C2-NHS ester
ADC Linker Cancer

Mal-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130376

Propargyl-PEG8-NHS ester
ADC Linker Cancer

Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126890

Bis-PEG7-NHS ester
ADC Linker Cancer

Bis-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130824

Bis-PEG10-NHS ester
ADC Linker Cancer

Bis-PEG10-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-117031

m-PEG8-Ms
ADC Linker Cancer

m-PEG8-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130410

Bis-PEG6-NHS ester
ADC Linker Cancer

Bis-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-112099

Mc-Val-Cit-PAB-Cl	ADC Linker	Cancer
Mc-Val-Cit-PAB-Cl is a cleavable ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC₅₀s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).

HY-120702

N-Boc-PEG5-bromide
ADC Linker Cancer

N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W006445

N-Boc-PEG3-bromide
ADC Linker Cancer

N-Boc-PEG3-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-116427

Propargyl-PEG4-thiol
ADC Linker Cancer

Propargyl-PEG4-thiol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130328

NH-bis-PEG2
ADC Linker Cancer

NH-bis-PEG2 is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126523

N3-C5-NHS ester
ADC Linker Cancer

N3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130372

Propargyl-PEG9-bromide
ADC Linker Cancer

Propargyl-PEG9-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136154

Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP
ADC Linker Cancer

Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126521

N3-C3-NHS ester
ADC Linker Cancer

N3-C3-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130505

N-Boc-PEG7-alcohol
ADC Linker Cancer

N-Boc-PEG7-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141143

MC(C5)-Val-Cit
ADC Linker Cancer

MC(C5)-Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126495A

Sulfo-SPDP-C6-NHS sodium
ADC Linker Cancer

Sulfo-SPDP-C6-NHS sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-131086

Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2	ADC Linker	Cancer Inflammation/Immunology
Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W071584

N-Boc-PEG6-alcohol
ADC Linker Cancer

N-Boc-PEG6-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130097

Ald-Ph-amido-PEG4-C2-acid
ADC Linker Cancer

Ald-Ph-amido-PEG4-C2-acid is a noncleavable linker used for the antibody-drug conjugate (ADC).
HY-126522

N3-C4-NHS ester
ADC Linker Cancer

N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W046471

N-Boc-PEG4-bromide
ADC Linker Cancer

N-Boc-PEG4-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130503

N-Boc-PEG2-bromide
ADC Linker Cancer

N-Boc-PEG2-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133584

Bis-SS-C3-NHS ester
ADC Linker Cancer

Bis-SS-C3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130591

Propargyl-PEG4-Br
ADC Linker Cancer

Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130475

Azido-PEG9-acid
ADC Linker Cancer Inflammation/Immunology

Azido-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126520

N3-C2-NHS ester
ADC Linker Cancer

N3-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126676

DBCO-(PEG2-Val-Cit-PAB)2
ADC Linker Cancer

DBCO-(PEG2-Val-Cit-PAB)2 is a dual cleavable ADC linker for antibody-drug conjugates (ADCs).
HY-130377

Propargyl-PEG8-bromide
ADC Linker Cancer

Propargyl-PEG8-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W071583

N-Boc-PEG9-alcohol
ADC Linker Cancer

N-Boc-PEG9-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126960

Mal-PEG1-acid
ADC Linker Cancer Inflammation/Immunology

Mal-PEG1-acid is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)
HY-140126

Bis-Tos-(2-hydroxyethyl disulfide)
ADC Linker Cancer

Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-125541

DBCO-NHCO-PEG4-acid
ADC Linker Cancer

DBCO-Amide-PEG5-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136261

DM1-PEG4-DBCO	Drug-Linker Conjugates for ADC	Cancer
DM1-(PEG)4-DBCO is a drug-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.

HY-136260

DBCO-PEG4-Ahx-DM1	Drug-Linker Conjugates for ADC	Cancer
DBCO-PEG4-Ahx-DM1 is a drug-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.

HY-P1449

Boc-Gly-Gly-Phe-Gly-OH	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-130165

Tr-PEG8-OH
ADC Linker Cancer Inflammation/Immunology

Tr-PEG8-OH is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141355

OPSS-PEG36-acid
ADC Linker Cancer

OPSS-PEG36-acid is a cleavable 36 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-120845

Tr-PEG5-OH
ADC Linker Cancer Inflammation/Immunology

Tr-PEG5-OH is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136287

DBM-MMAF
Drug-Linker Conjugates for ADC Cancer

DBM-MMAF is a drug-linker conjugate composed of a potent antitubulin agent MMAF and a linker DBM to make antibody drug conjugate (ADC).
HY-126883

Tr-PEG4-OH
PROTAC Linker Cancer Inflammation/Immunology

Tr-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136106

Fmoc-Gly3-Val-Cit-PAB
ADC Linker Cancer

Fmoc-Gly3-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W040254

Biotin-LC-LC-NHS
Others Others

Biotin-LC-LC-NHS is a SMCC cross-linking reagent that can be used to mark antibody and other small molecules, such as Paclitaxel.
HY-136432

Mc-Gly-Gly-Phe-Gly-PAB-OH
Mc-GGFG-PAB-OH
ADC Linker Cancer

Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
HY-141123

SPDP-C6-Gly-Leu-NHS ester
ADC Linker Cancer

SPDP-C6-Gly-Leu-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130222

Mal-PEG2-Val-Cit-amido-PAB-OH
ADC Linker Cancer

Mal-PEG2-Val-Cit-amido-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133408

4-Methyl-4-(methyldisulfanyl)pentanoic acid	ADC Linker	Cancer
4-Methyl-4-(methyldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-126884

DBCO-NHCO-PEG4-NH-Boc
ADC Linker Cancer

DBCO-NHCO-PEG4-NH-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126525

4-N3Pfp-NHS ester
ADC Linker Cancer

4-N3Pfp-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W042654

BnO-PEG6-OH
ADC Linker Cancer Inflammation/Immunology

BnO-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129311

Tr-PEG6-OH
ADC Linker Cancer Inflammation/Immunology

Tr-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133585

Bis-SS-C3-sulfo-NHS ester
ADC Linker Cancer

Bis-SS-C3-sulfo-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133066

m-PEG6-NHS ester
ADC Linker Cancer Inflammation/Immunology

m-PEG6-NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-120258

Tr-PEG3-OH
ADC Linker Cancer Inflammation/Immunology

Tr-PEG3-OH is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-115374

m-PEG6-azide
ADC Linker Cancer Inflammation/Immunology

m-PEG6-azide is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141353

SPDP-PEG12-acid
ADC Linker Cancer

SPDP-PEG12-acid is a cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135971

BCN-PEG4-acid
ADC Linker Cancer

BCN-PEG4-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W019793

m-PEG8-NHS ester
ADC Linker Cancer Inflammation/Immunology

m-PEG8-NHS ester is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126958

Biotin-PEG2-acid
ADC Linker Cancer Inflammation/Immunology

Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136051

Biotin-PEG3-aldehyde
ADC Linker Cancer

Biotin-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136099

Bocaminooxyacetamide-PEG2-Azido
ADC Linker Cancer

Bocaminooxyacetamide-PEG2-Azido is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136044

APN-PEG4-BCN
ADC Linker Cancer

APN-PEG4-BCN is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-118764

Propargyl-PEG2-acid
ADC Linker Cancer

Propargyl-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136309

Ald-PEG23-SPDP
ADC Linker Cancer

Ald-PEG23-SPDP is a cleavable 23 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130080

DM3 Maytansinoid DM3	ADC Cytotoxin Microtubule/Tubulin	Cancer
DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs).

HY-140115

Bis-(PEG6-acid)-SS
ADC Linker Cancer

Bis-(PEG6-acid)-SS is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136091

Aldehyde PEG23-thiol
ADC Linker Cancer

Aldehyde PEG23-thiol is a cleavable 23 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130449

N-Boc-N-bis(PEG4-OH)
ADC Linker Cancer

N-Boc-N-bis(PEG4-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140454

Azido-PEG8-acid
ADC Linker Cancer

Azido-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136052

Tetrazine-PEG4-oxyamine hydrochloride	ADC Linker	Cancer
Tetrazine-PEG4-oxyamine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-135961

PTAD-PEG4-amine
ADC Linker Cancer

PTAD-PEG4-amine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136086

Tetrazine-PEG6-amine hydrochloride
ADC Linker Cancer

Tetrazine-PEG6-amine (hydrochloride) is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136049

APN-PEG4-DBCO
ADC Linker Cancer

APN-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-116655

Hydroxy-PEG1-acid
ADC Linker Cancer

Hydroxy-PEG1-acid is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135974

Amino-PEG3-SS-acid
ADC Linker Cancer

Amino-PEG3-SS-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135125

DC4
ADC Cytotoxin Cancer

DC4, a ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4 can be used for the targeted treatment of cancer.
HY-140244

Gly-PEG3-amine
ADC Linker Cancer

Gly-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136046

PTAD-PEG4-alkyne
ADC Linker Cancer

PTAD-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W019799

Amino-PEG8-Boc
ADC Linker Cancer

Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140097

Amino-SS-PEG12-acid
ADC Linker Cancer

Amino-SS-PEG12-acid is a cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136045

APN-PEG4-tetrazine
ADC Linker Cancer

APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136067

DBCO-PEG4-HyNic
ADC Linker Cancer

DBCO-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136048

Methylcyclopropene-PEG4-NHS
ADC Linker Cancer

Methylcyclopropene-PEG4-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-P1449A

Boc-Gly-Gly-Phe-Gly-OH TFA	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-136127

ALD-PEG4-OPFP
ADC Linker Cancer

ALD-PEG4-OPFP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-117104

Hydroxy-PEG4-acid
ADC Linker Cancer

Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136077

TCO-PEG3-aldehyde
ADC Linker Cancer

TCO-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136061

BCN-PEG4-HyNic
ADC Linker Cancer

BCN-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135964

(2-pyridyldithio)-PEG4 acid
ADC Linker Cancer

(2-pyridyldithio)-PEG4 acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136050

TCO-PEG3-Biotin
ADC Linker Cancer

TCO-PEG3-Biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-117079

N-Boc-N-bis(PEG2-OH)
ADC Linker Cancer

N-Boc-N-bis(PEG2-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136075

HyNic-PEG4-alkyne
ADC Linker Cancer

HyNic-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136047

Methylcyclopropene-PEG3-amine
ADC Linker Cancer

Methylcyclopropene-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136101

Bocaminooxyacetamide-PEG3-alkyne
ADC Linker Cancer

Bocaminooxyacetamide-PEG3-alkyne is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136074

Methyltetrazine-PEG4-aldehyde
ADC Linker Cancer

Methyltetrazine-PEG4-aldehyde is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141358

SPDP-PEG36-NHS ester
ADC Linker Cancer

SPDP-PEG36-NHS ester is a cleavable 36 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-120537

m-PEG5-CH2COOH
ADC Linker Cancer

m-PEG5-CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130939

APN-PEG4-Amine hydrochloride
ADC Linker Cancer

APN-PEG4-Amine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136053

Tetrazine-PEG4-biotin
ADC Linker Cancer

Tetrazine-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130977

Tetrazine-PEG4-amine hydrochloride
ADC Linker Cancer

Tetrazine-PEG4-amine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130150

m-PEG5-succinimidyl carbonate	ADC Linker	Cancer Inflammation/Immunology
m-PEG5-succinimidyl carbonate is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-140352

Azide-PEG5-Tos
ADC Linker Cancer

Azide-PEG5-Tos is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136038

Azido-PEG3-SSPy
ADC Linker Cancer

Azido-PEG3-SSPy is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130151

m-PEG7-CH2COOH
ADC Linker Cancer

m-PEG7-CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136056

Methyltetrazine-PEG4-oxyamine
ADC Linker Cancer

Methyltetrazine-PEG4-oxyamine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130925

BCN-PEG4-OH
ADC Linker Cancer

BCN-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126942

Amino-PEG6-alcohol
ADC Linker Cancer

Amino-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133433

DBCO-PEG4-VA-PBD
ADC Linker Cancer

DBCO-PEG4-VA-PBD is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140078

bis-PEG2-endo-BCN
ADC Linker Cancer

bis-PEG2-endo-BCN is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133431

DBCO-PEG3-SS-NHS ester
ADC Linker Cancer

DBCO-PEG3-SS-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-128960

DBA-DM4
Drug-Linker Conjugates for ADC Cancer

DBA-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM1 and a linker SPDP to make antibody drug conjugate (ADC).
HY-135962

Boc-Aminooxy-PEG2-bromide
ADC Linker Cancer

Boc-Aminooxy-PEG2-bromide is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140124

THP-SS-PEG1-Tos
ADC Linker Cancer

THP-SS-PEG1-Tos is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130924

BCN-PEG3-Biotin
ADC Linker Cancer

BCN-PEG3-Biotin is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135966

Azido-PEG3-SS-NHS
ADC Linker Cancer

Azido-PEG3-SS-NHS is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W040165

Amino-PEG3-C2-acid
ADC Linker Cancer

Amino-PEG3-C2-acid is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130926

BCN-PEG3-oxyamine
ADC Linker Cancer

BCN-PEG3-oxyamine is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130324

Azido-PEG7-amine
ADC Linker Cancer

Azido-PEG7-amine is a non-cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136041

Boc-amino-PEG3-SSPy
ADC Linker Cancer

Boc-amino-PEG3-SSPy is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140130

PC Biotin-PEG3-alkyne
ADC Linker Cancer

PC Biotin-PEG3-alkyne is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140123

THP-SS-PEG1-Boc
ADC Linker Cancer

THP-SS-PEG1-Boc is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130927

BCN-PEG4-Ts
ADC Linker Cancer

BCN-PEG4-Ts is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-135660

MMAE-SMCC	Drug-Linker Conjugates for ADC	Cancer
MMAE-SMCC is a drug-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody drug conjugate.

HY-133466

Methyltetrazine-PEG4-SS-NHS ester
ADC Linker Cancer

Methyltetrazine-PEG4-SS-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140108

Propargyl-PEG1-SS-alcohol
ADC Linker Cancer

Propargyl-PEG1-SS-alcohol is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136035

Methyltetrazine-SS-PEG4-Biotin
ADC Linker Cancer

Methyltetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133434

Aminoxyacetamide-PEG3-azide
ADC Linker Cancer

Aminoxyacetamide-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133428

DBCO-PEG3-TCO
ADC Linker Cancer

DBCO-PEG3-TCO is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136096

DBCO-PEG3 acetic-EVCit-PAB
ADC Linker Cancer

DBCO-PEG3 acetic-EVCit-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130298

Amino-PEG11-OH
ADC Linker Cancer

Amino-PEG11-OH is non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133430

DBCO-PEG4-alkyne
ADC Linker Cancer

DBCO-PEG4-alkyne is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-112561

Bis-PEG1-PFP ester
ADC Linker Cancer Inflammation/Immunology

Bis-PEG1-PFP ester is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130955

Amino-bis-PEG3-TCO
ADC Linker Cancer

Amino-bis-PEG3-TCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140134

PC Biotin-PEG3-NHS ester
ADC Linker Cancer

PC Biotin-PEG3-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140152

BCN-PEG3-VC-PFP ester
ADC Linker Cancer

BCN-PEG3-VC-PFP ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136078

Tetrazine-diazo-PEG4-biotin
ADC Linker Cancer

Tetrazine-diazo-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133432

DBCO-PEG4-SS-TCO
ADC Linker Cancer

DBCO-PEG4-SS-TCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130945

Tetrazine-PEG5-SS-amine
ADC Linker Cancer

Tetrazine-PEG5-SS-amine is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-112805

FCHFHS-ST7612AA1
Drug-Linker Conjugates for ADC Cancer

FCHFHS-ST7612AA1 is a part of antibody drug conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity.
HY-130972

Amino-bis-PEG3-DBCO
ADC Linker Cancer

Amino-bis-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136087

Mal-bis-PEG3-DBCO
ADC Linker Cancer

Mal-bis-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136079

Methyltetrazine-PEG4-hydrazone-DBCO
ADC Linker Cancer

Methyltetrazine-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140139

PC Alkyne-PEG4-NHS ester
ADC Linker Cancer

PC Alkyne-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136040

Tetrazine-PEG4-SS-NHS
ADC Linker Cancer

Tetrazine-PEG4-SS-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136085

Amino-bis-PEG3-BCN
ADC Linker Cancer

Amino-bis-PEG3-BCN is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-P1787

β-Amyloid (4-10)	Amyloid-β	Neurological Disease
β-Amyloid (4-10) is an epitope for the polyclonal anti-Aβ(1-42) antibody, reduces amyloid deposition in a transgenic Alzheimer disease mouse model.

HY-136097

Maleimide-PEG2-hydrazide TFA
ADC Linker Cancer

Maleimide-PEG2-hydrazide (TFA) is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140930

Diazo Biotin-PEG3-DBCO
ADC Linker Cancer

Diazo Biotin-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136036

Tetrazine-SS-PEG4-Biotin
ADC Linker Cancer

Tetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133538

4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene	ADC Linker	Cancer
4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130169

Azido-PEG9-amine
ADC Linker Cancer

Azido-PEG9-amine is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133427

Propargyl-PEG4-hydrazide
ADC Linker Cancer

Propargyl-PEG4-hydrazide is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133429

DBCO-PEG3-oxyamine
ADC Linker Cancer

DBCO-PEG3-oxyamine is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136037

Boc-amino-PEG3-SS-acid
ADC Linker Cancer

Boc-amino-PEG3-SS-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140944

Biotin-PEG3-SS-azide
ADC Linker Cancer

Biotin-PEG3-SS-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140132

PC Biotin-PEG3-azide
ADC Linker Cancer

PC Biotin-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130947

Tetrazine-PEG4-SS-Py
ADC Linker Cancer

Tetrazine-PEG4-SS-Py is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140136

PC DBCO-PEG3-biotin
ADC Linker Cancer

PC DBCO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-115384

Amino-PEG5-C2-acid
ADC Linker Cancer

Amino-PEG5-C2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135979

DBCO-SS-PEG4-Biotin
ADC Linker Cancer

DBCO-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-120761

Amino-PEG10-OH
ADC Linker Cancer

Amino-PEG10-OH is non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130485

Bromo-PEG2-C2-azide
ADC Linker Cancer

Bromo-PEG2-C2-azide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130934

TCO-PEG1-Val-Cit-OH
ADC Linker Cancer

TCO-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140309

Gly-Gly-Gly-PEG4-DBCO
ADC Linker Cancer

Gly-Gly-Gly-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141190

Gly-Gly-Gly-PEG3-TCO
ADC Linker Cancer

Gly-Gly-Gly-PEG3-TCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141292

Oleoyl-Gly-Lys-N-(m-PEG11)
ADC Linker Cancer

Oleoyl-Gly-Lys-N-(m-PEG11) is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130103

Ald-Ph-amido-PEG2-C2-Pfp ester
ADC Linker Cancer

Ald-Ph-amido-PEG2-C2-Pfp ester is a nonclaevable 2-unit PEG linker for antibody-drug-conjugation (ADC).
HY-130106

Ald-Ph-amido-PEG1-C2-NHS ester
ADC Linker Cancer

Ald-Ph-amido-PEG1-C2-NHS ester is a nonclaevable 1-unit PEG linker for antibody-drug-conjugation (ADC).
HY-130182

Propargyl-PEG8-NH2
ADC Linker Cancer

Propargyl-PEG8-NH2 (compound 3b) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136134

SS-bis-amino-PEG4-NHS ester
ADC Linker Cancer

SS-bis-amino-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130104

Ald-Ph-amido-PEG2-C2-NHS ester
ADC Linker Cancer

Ald-Ph-amido-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-drug-conjugation (ADC).
HY-136034

Azido-PEG1-Val-Cit-OH
ADC Linker Cancer

Azido-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126510

MC-PEG2-C2-NHS ester
ADC Linker Cancer

MC-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136135

(2-pyridyldithio)-PEG1-hydrazine
ADC Linker Cancer

(2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133544

Mal-CO-PEG5-NHS ester
ADC Linker Cancer

Mal-CO-PEG5-NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-42640

Boc-NH-PEG4-CH2COOH
ADC Linker Cancer

Boc-NH-PEG4-CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC).
HY-130940

PTAD-PEG4-N3
ADC Linker Cancer

PTAD-PEG4-N3 is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133062

Fmoc-NH-PEG5-CH2COOH
ADC Linker Cancer

Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128930

6-O-2-Propyn-1-yl-D-galactose	ADC Linker	Cancer
6-O-2-Propyn-1-yl-D-galactose is a nonclaevable glycolinker for the functionalization of cytotoxic drugs and applications in antibody-drug conjugation.

HY-130922

BCN-PEG1-Val-Cit-OH
ADC Linker Cancer

BCN-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130364

Fmoc-NH-PEG6-CH2COOH
ADC Linker Cancer

Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-131087

Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc	ADC Linker	Cancer
Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-140127

Azide-C2-SS-C2-biotin
ADC Linker Cancer

Azide-C2-SS-C2-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130094

NHPI-PEG2-C2-Pfp ester
ADC Linker Cancer

NHPI-PEG2-C2-Pfp ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140099

Amino-ethyl-SS-PEG3-NHBoc
ADC Linker Cancer

Amino-ethyl-SS-PEG3-NHBoc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141284

Gly-Gly-Gly-PEG4-methyltetrazine
ADC Linker Cancer

Gly-Gly-Gly-PEG4-methyltetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133435

Aminooxy-amido-PEG4-propargyl
ADC Linker Cancer

Aminooxy-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130105

Ald-Ph-amido-PEG1-C2-Pfp ester
ADC Linker Cancer

Ald-Ph-amido-PEG1-C2-Pfp ester is a nonclaevable 1-unit PEG linker for antibody-drug-conjugation (ADC).
HY-133063

Fmoc-NH-PEG8-CH2COOH
ADC Linker Cancer

Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W055861

Fmoc-NH-PEG1-CH2COOH
ADC Linker Cancer

Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130095

NHPI-PEG2-C2-NHS ester
ADC Linker Cancer

NHPI-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136141

DBCO-PEG3-propionic EVCit-PAB
ADC Linker Cancer

DBCO-PEG3-propionic EVCit-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130101

Ald-Ph-amido-PEG4-C2-NHS ester
ADC Linker Cancer

Ald-Ph-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-drug-conjugation (ADC).

HY-15582

Auristatin E	Microtubule/Tubulin ADC Cytotoxin	Cancer
Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates. Auristatin E inhibits cell division by blocking the polymerisation of tubulin.

HY-130175

Fmoc-NH-PEG4-CH2COOH
ADC Linker Cancer

Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130092

NHPI-PEG3-C2-Pfp ester
ADC Linker Cancer

NHPI-PEG3-C2-Pfp ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130093

NHPI-PEG3-C2-NHS ester
ADC Linker Cancer

NHPI-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133459

Mal-PEG1-Val-Cit-OH
ADC Linker Cancer

Mal-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130962

Ald-Ph-amido-PEG23-OPSS
ADC Linker Cancer

Ald-Ph-amido-PEG23-OPSS is a cleavable 23 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130954

Hynic-PEG3-N3
ADC Linker Cancer

Hynic-PEG3-N3 is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-126350

CL2-SN-38	Drug-Linker Conjugates for ADC	Cancer
CL2-SN-38 is a part of the antibody drug conjugate (ADC), can conjugate with the anti-Trop-2-humanized antibody hRS7. SN-38 is a DNA topoisomerase I inhibitor. The anti-Trop-2 hRS7-CL2A-SN-38 ADC provides significant and specific antitumor effects against a range of human solid tumor types.

HY-130941

Fmoc-N-bis-PEG3-NH-Boc
ADC Linker Cancer

Fmoc-N-bis-PEG3-NH-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140145

Mal-PEG4-Val-Cit-PAB-PNP
ADC Linker Cancer

Mal-PEG4-Val-Cit-PAB-PNP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136137

Azide-PEG1-Val-Cit-PABC-OH
ADC Linker Cancer

Azide-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140148

Azido-PEG3-Val-Cit-PAB-OH
ADC Linker Cancer

Azido-PEG3-Val-Cit-PAB-OH is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133576

Cyclooctyne-O-amido-PEG4-PFP ester	ADC Linker	Cancer
Cyclooctyne-O-amido-PEG4-PFP ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133575

Cyclooctyne-O-amido-PEG3-PFP ester	ADC Linker	Cancer
Cyclooctyne-O-amido-PEG3-PFP ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-141150

Azido-PEG5-Ala-Ala-Asn-PAB
ADC Linker Cancer

Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133578

Cyclooctyne-O-amido-PEG3-NHS ester	ADC Linker	Cancer
Cyclooctyne-O-amido-PEG3-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133545

Mal-Ph-CONH-PEG4-NHS ester
ADC Linker Cancer

Mal-Ph-CONH-PEG4-NHS ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136100

TCO-PEG1-Val-Cit-PABC-PNP
ADC Linker Cancer

TCO-PEG1-Val-Cit-PABC-PNP is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136108

Fmoc-Gly3-Val-Cit-PAB-PNP
ADC Linker Cancer

Fmoc-Gly3-Val-Cit-PAB-PNP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141149

Fmoc-PEG4-Ala-Ala-Asn-PAB
ADC Linker Cancer

Fmoc-PEG4-Ala-Ala-Asn-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141156

Mal-PEG8-Val-Cit-PAB-MMAE
ADC Linker Cancer

Mal-PEG8-Val-Cit-PAB-MMAE is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W040168

Amino-PEG2-C2-acid
ADC Linker Cancer

Amino-PEG2-C2-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136157

Py-ds-dmBut-amido-PEG4-NHS ester
ADC Linker Cancer

Py-ds-dmBut-amido-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133426

Ald-Ph-amido-PEG4-propargyl Ald-benzyl-amide-PEG4-propargyl	ADC Linker	Cancer
Ald-Ph-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-140113

Acid-PEG3-SS-PEG3-acid
ADC Linker Cancer

Acid-PEG3-SS-PEG3-acid is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130966

TCO-PEG1-Val-Cit-PABC-OH
ADC Linker Cancer

TCO-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130091

NHPI-PEG4-C2-NHS ester
ADC Linker Cancer

NHPI-PEG4-C2-NHS ester, example 40 (WO2014185985A1), is used as a linker for antibody-drug conjugates (ADC).

HY-112806

MAC-VC-PABC-ST7612AA1	Drug-Linker Conjugates for ADC	Cancer
MAC-VC-PABC-ST7612AA1 is a part of antibody drug conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity.

HY-136155

Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester	ADC Linker	Cancer
Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136098

DBCO-PEG4-acetic-Val-Cit-PAB
ADC Linker Cancer

DBCO-PEG4-acetic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136054

N3-PEG5-aldehyde
ADC Linker Cancer

N3-PEG5-aldehyde is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140143

Mal-PEG4-Val-Cit-PAB-OH
ADC Linker Cancer

Mal-PEG4-Val-Cit-PAB-OH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-112901

DC41
ADC Cytotoxin Cancer

DC41 is a DC1 derivative. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer.
HY-141154

Amino-PEG4-Val-Cit-PAB-MMAE
ADC Linker Cancer

Amino-PEG4-Val-Cit-PAB-MMAE is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-131082

(R)-8-Azido-2-(Fmoc-amino)octanoic acid
ADC Linker Cancer

(R)-8-Azido-2-(Fmoc-amino)octanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W019798

NH2-PEG9-acid
ADC Linker Cancer

NH2-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140112

Acid-PEG2-SS-PEG2-acid
ADC Linker Cancer

Acid-PEG2-SS-PEG2-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133580

Cyclooctyne-O-amido-PEG2-NHS ester	ADC Linker	Cancer
Cyclooctyne-O-amido-PEG2-NHS ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130944

Mal-PEG1-Val-Cit-PABC-OH
ADC Linker Cancer

Mal-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133577

Cyclooctyne-O-amido-PEG4-NHS ester	ADC Linker	Cancer
Cyclooctyne-O-amido-PEG4-NHS ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136286

MC-DM1	Drug-Linker Conjugates for ADC	Cancer
MC-DM1 is a drug-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker MC to make antibody drug conjugate (ADC).

HY-133436

Boc-aminooxy-amide-PEG4-propargyl
ADC Linker Cancer

Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133573

Cyclooctyne-O-amido-PEG2-PFP ester	ADC Linker	Cancer
Cyclooctyne-O-amido-PEG2-PFP ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133579

Ald-Ph-amido-PEG3-NHS ester
ADC Linker Cancer

Ald-Ph-amido-PEG3-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126669

Mal-PEG4-VA
ADC Linker Cancer

Mal-PEG4-VA is a noncleavable ADC linker containing a Maleimide group. Mal-PEG4-VA is used for making antibody-drug conjugate.
HY-136103

DBCO-PEG4-Propionic-Val-Cit-PAB
ADC Linker Cancer

DBCO-PEG4-Propionic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133409

4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid	ADC Linker	Cancer
4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136105

Azido-PEG1-Val-Cit-PABC-PNP
ADC Linker Cancer

Azido-PEG1-Val-Cit-PABC-PNP is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130923

BCN-PEG1-Val-Cit-PABC-OH
ADC Linker Cancer

BCN-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141155

endo-BCN-PEG4-Val-Cit-PAB-MMAE
ADC Linker Cancer

endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141151

Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB
ADC Linker Cancer

Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-112899

DC1	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin. DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer.

HY-140147

Mal-amido-PEG2-Val-Cit-PAB-PNP
ADC Linker Cancer

Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-111456

DBCO-NHCO-PEG4-NHS ester	ADC Linker	Cancer
DBCO-NHCO-PEG4-NHS ester ester is a MMP-2- and cathepsin B- (CatB) cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-141146

Mal-amido-PEG8-val-gly-PAB-OH
ADC Linker Cancer

Mal-amido-PEG8-val-gly-PAB-OH is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133572

Ald-Ph-amido-PEG11-NH-Boc
ADC Linker Cancer

Ald-Ph-amido-PEG11-NH-Boc is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130185

m-PEG7-CH2CH2CHO
ADC Linker Cancer

m-PEG7-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140146

Mal-amido-PEG2-Val-Cit-PAB-OH
ADC Linker Cancer

Mal-amido-PEG2-Val-Cit-PAB-OH is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130144

Ald-CH2-PEG3-azide
ADC Linker Cancer

Ald-CH2-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128873

Duocarmycin GA	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
Duocarmycin GA is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin GA can be used against multi-drug resistant cell lines.

HY-W067509

m-PEG3-CH2CH2COOH
ADC Linker Cancer

m-PEG3-CH2CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-107770

Duocarmycin MB	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
Duocarmycin MB is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MB can be used against multi-drug resistant cell lines.

HY-115524

DBCO-NHS ester 2	ADC Linker	Cancer
DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry.

HY-130315

Br-PEG4-C2-Boc
ADC Linker Cancer

Br-PEG4-C2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W035376

m-PEG6-CH2CH2CHO
ADC Linker Cancer

m-PEG6-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-18987

Duocarmycin MA	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
Duocarmycin MA is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MA can be used against multi-drug resistant cell lines.

HY-140109

Propargyl-PEG1-SS-PEG1-acid
ADC Linker Cancer

Propargyl-PEG1-SS-PEG1-acid is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136076

TCO-PEG3-CH2-aldehyde
ADC Linker Cancer

TCO-PEG3-CH2-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136292

MC-PBD	Drug-Linker Conjugates for ADC	Cancer
MC-PBD consists a non-cleavable ADC linker MC and a cytotoxic DNA crosslinking pyrrolobenzodiazepine (PBD). MC-PBD can be used in the synthesis of antibody-drug conjugates (ADCs).

HY-136318

β-D-tetraacetylgalactopyranoside-PEG1-N3	ADC Linker	Cancer
β-D-tetraacetylgalactopyranoside-PEG1-N3 is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136131

NH2-PEG4-hydrazone-DBCO
ADC Linker Cancer

NH2-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136133

NHS-PEG2-SS-PEG2-NHS
ADC Linker Cancer

NHS-PEG2-SS-PEG2-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140121

m-PEG6-SS-PEG6-methyl
ADC Linker Cancer

m-PEG6-SS-PEG6-methyl is a cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136058

N3-PEG4-amido-Lys(Fmoc)-acid
ADC Linker Cancer

N3-PEG4-amido-Lys(Fmoc)-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126529

N3-PEG3-C2-PFP ester
ADC Linker Cancer

N3-PEG3-C2-PFP ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135970

Alkyne-PEG4-SS-PEG4-alkyne
ADC Linker Cancer

Alkyne-PEG4-SS-PEG4-alkyne is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130968

Amino-PEG4-bis-PEG3-propargyl
ADC Linker Cancer

Amino-PEG4-bis-PEG3-propargyl is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130929

β-Estradiol-6-CMO-PEG3-biotin
ADC Linker Cancer

β-Estradiol-6-CMO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136088

Acid-PEG1-bis-PEG3-BCN
ADC Linker Cancer

Acid-PEG1-bis-PEG3-BCN is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133581

Mal-PEG3-C1-NHS ester
ADC Linker Cancer

Mal-PEG3-C1-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130973

Mal-PEG4-bis-PEG4-propargyl
ADC Linker Cancer

Mal-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128871

VCP-Eribulin	Drug-Linker Conjugates for ADC	Cancer
VCP-Eribulin consists the ADCs linker (VCP) and Eribulin. Eribulin is a mechanistically unique microtubule inhibitor for cancer. VCP-Eribulin is an Eribulin-based drug for antibody conjugates.

HY-130108

N3-PEG4-C2-Pfp ester
ADC Linker Cancer

N3-PEG4-C2-Pfp ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130971

Mal-PEG4-bis-PEG3-DBCO
ADC Linker Cancer

Mal-PEG4-bis-PEG3-DBCO is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130943

Methyltetrazine-PEG4-SS-PEG4-methyltetrazine	ADC Linker	Cancer
Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-140111

Propargyl-PEG1-SS-PEG1-propargyl
ADC Linker Cancer

Propargyl-PEG1-SS-PEG1-propargyl is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130970

Amino-PEG4-bis-PEG3-methyltetrazine
ADC Linker Cancer

Amino-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126527

N3-PEG2-C2-PFP ester
ADC Linker Cancer

N3-PEG2-C2-PFP ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130083

Seco-Duocarmycin TM	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
Seco-Duocarmycin TM is a DNA alkylator agent belonging to Duocarmycins family that inhibits DNA synthesis. Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates (ADC)^[1].

HY-129526

Mal-PEG3-NHS ester
ADC Linker Cancer

Mal-PEG3-NHS ester is a noncleavable ADC linker containing a Maleimide group. Mal-PEG3-NHS ester is used for making antibody-drug conjugate.
HY-130953

Mal-PEG4-bis-PEG3-methyltetrazine
ADC Linker Cancer

Mal-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136089

Aminooxy-PEG2-bis-PEG3-DBCO
ADC Linker Cancer

Aminooxy-PEG2-bis-PEG3-DBCO is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140110

Propargyl-PEG1-SS-PEG1-PFP ester
ADC Linker Cancer

Propargyl-PEG1-SS-PEG1-PFP ester is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130379

Propargyl-PEG8-acid	ADC Linker Bacterial	Cancer Infection
Propargyl-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria.

HY-126528

N3-PEG3-C2-NHS ester
ADC Linker Cancer

N3-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128915

Duocarmycin	DNA Alkylator/Crosslinker	Cancer
Duocarmycin is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity. Duocarmycin is a DNA minor groove binding alkylating agent and explored as drug–antibody conjugates (ADCs) .

HY-126526

N3-PEG2-C2-NHS ester
ADC Linker Cancer

N3-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-114816

N-Butanoyl-L-homoserine lactone C4-HSL; N-Butyryl-L-homoserine lactone	ADC Linker Bacterial	Infection
N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm.

HY-140634

Ald-CH2-PEG5-azide
ADC Linker Cancer

Ald-CH2-PEG5-azide is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140133

PC-Biotin-PEG4-PEG3-azide
ADC Linker Cancer

PC-Biotin-PEG4-PEG3-azide is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136060

Mal-PEG2-bis-PEG3-BCN
ADC Linker Cancer

Mal-PEG2-bis-PEG3-BCN is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130109

N3-PEG4-C2-NHS ester
ADC Linker Cancer

N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130167

Fmoc-NH-PEG9-CH2CH2COOH
ADC Linker Cancer

Fmoc-NH-PEG9-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-101150

DGN462	DNA Alkylator/Crosslinker	Cancer
DGN462, a potent DNA-alkylating agent, shows anti-tumor activity, such as acute myeloid leukemia (AML). DGN462 can be used as a cytotoxic component of antibody-drug conjugates (ADCs).

HY-130690

Propargyl-PEG1-SS-PEG1-C2-Boc
ADC Linker Cancer

Propargyl-PEG1-SS-PEG1-C2-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W040135

Fmoc-NH-PEG8-CH2CH2COOH
ADC Linker Cancer

Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128880

(+)-CBI-CDPI1	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
(+)-CBI-CDPI1 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI1 is an antibody drug conjugates (ADCs) toxin.

HY-133574

Mal-amido-PEG3-C1-PFP ester
ADC Linker Cancer

Mal-amido-PEG3-C1-PFP ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W040238

Fmoc-NH-PEG2-CH2CH2COOH
ADC Linker Cancer

Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126514

Propargyl-O-C1-amido-PEG2-C2-NHS ester
ADC Linker Cancer

Propargyl-O-C1-amido-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-drug-conjugation (ADC).

HY-130817

Mc-O-Si(di-iso)-Cl	ADC Linker	Cancer
Mc-O-Si(di-iso)-Cl is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) ).

HY-W040246

Fmoc-NH-PEG6-CH2CH2COOH
ADC Linker Cancer

Fmoc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128881

(+)-CBI-CDPI2	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
(+)-CBI-CDPI2 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI2 is an antibody drug conjugates (ADCs) toxin.

HY-130967

Ald-Ph-PEG4-bis-PEG4-propargyl
ADC Linker Cancer

Ald-Ph-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130974

Ald-Ph-PEG4-bis-PEG3-methyltetrazine	ADC Linker	Cancer
Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-141091

Biotin-PEG4-Dde-TAMRA-PEG3-Azide
ADC Linker Cancer

Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130572

Azido-PEG5-acid	ADC Linker	Cancer Inflammation/Immunology
Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as the conjugate CPT-APO (CPT: Camptothecin (HY-16560)).

HY-126678

Dimethyl-SGD-1882 Dimethyl-PBD dimer	ADC Cytotoxin	Cancer
Dimethyl-SGD-1882 (Dimethyl-PBD dimer) is a highly potent DNA alkylator, and is used as an antibody-drug conjugate (ADC) cytotoxin. PBD Dimer is a DNA alkylator which inhibits DNA replication.

HY-130931

Propargyl-NH-PEG3-C2-NHS ester
ADC Linker Cancer

Propargyl-NH-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128954

Sulfo-PDBA-DM4	Drug-Linker Conjugates for ADC	Cancer Inflammation/Immunology
Sulfo-PDBA-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Sulfo-PDBA to make antibody drug conjugate (ADC). Sulfo-PDBA is a gluthatione cleavable linker.

HY-133539

Propargyl-C8-amido-PEG2-NHS ester
ADC Linker Cancer

Propargyl-C8-amido-PEG2-NHS ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126515

Propargyl-O-C1-amido-PEG4-C2-NHS ester
ADC Linker Cancer

Propargyl-O-C1-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-drug-conjugation (ADC).
HY-133582

Mal-amido-PEG3-C1-NHS ester
ADC Linker Cancer

Mal-amido-PEG3-C1-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W040231

Fmoc-NH-PEG3-CH2CH2COOH
ADC Linker Cancer

Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W040244

Boc-NH-PEG6-CH2CH2COOH
ADC Linker Cancer

Boc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC).

HY-122907

JNJ4796	Influenza Virus	Infection
JNJ4796 is an oral active fusion inhibitor of influenza virus, neutralizing influenza A group 1 viruses by inhibiting hemagglutinin (HA)-mediated fusion. JNJ4796 mimics the functionality of the broadly neutralizing antibodies (bnAbs).

HY-W000434

Fmoc-NH-PEG4-CH2CH2COOH Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid	ADC Linker	Cancer
Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130546

Hydroxy-PEG3-SS-PEG3-alcohol
ADC Linker Cancer

Hydroxy-PEG3-SS-PEG3-alcohol is also a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-122872

MKK7-COV-9	p38 MAPK	Cancer
MKK7-COV-9 is a potent and selective covalent inhibitor of MKK7 and targets a specific protein–protein interaction of MKK7. MKK7-COV-9 blocks primary B cell activation in response to LPS with an EC₅₀ of 4.98 μM.

HY-130818

N-(5-Hydroxypentyl)maleimide	ADC Linker	Cancer
N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) ).

HY-W035378

Fmoc-N-methyl-PEG3-CH2CH2COOH
ADC Linker Cancer

Fmoc-N-methyl-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-44149

m-C-tri(CH2-PEG1-NHS ester)
ADC Linker Cancer

m-C-tri(CH2-PEG1-NHS ester) is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-121805

DBCO-C6-acid	ADC Linker	Cancer
DBCO-C6-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be used in the synthesis of carmaphycin analogues.

HY-136090

Amino-PEG4-bis-PEG3-N3
ADC Linker Cancer

Amino-PEG4-bis-PEG3-N3 is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130194

Azido-PEG5-CH2CO2H
ADC Linker Cancer

Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140101

Azido-C2-SS-PEG2-C2-acid
ADC Linker Cancer

Azido-C2-SS-PEG2-C2-acid is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-101070

SMCC-DM1 DM1-SMCC	Drug-Linker Conjugates for ADC	Cancer
SMCC-DM1 (DM1-SMCC) is a drug-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody drug conjugate (ADC).

HY-131085

Desmethyl Vc-seco-DUBA	Drug-Linker Conjugates for ADC	Cancer
Desmethyl Vc-seco-DUBA consists a cleavable ADC linker (Desmethyl Vc-seco) and a DNA alkylating agent (DUBA). Desmethyl Vc-seco-DUBA can be used in the synthesis of antibody-drug conjugates (ADCs).

HY-130957

Amino-PEG6-amido-bis-PEG5-N3
ADC Linker Cancer

Amino-PEG6-amido-bis-PEG5-N3 is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130969

Ald-Ph-PEG4-bis-PEG3-N3
ADC Linker Cancer

Ald-Ph-PEG4-bis-PEG3-N3 is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-126671

Mal-Phe-C4-Val-Cit-PAB	ADC Linker	Cancer
Mal-Phe-C4-Val-Cit-PAB is a cleavable ADC linker containing a Maleimide group. Mal-Phe-C4-Val-Cit-PAB is used for making antibody-drug conjugate.

HY-133546

Ald-Ph-amido-PEG11-C2-NH2
ADC Linker Cancer

Ald-Ph-amido-PEG11-C2-NH2 is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140242

NH2-PEG4-Lys(Boc)-NH-(m-PEG24)
ADC Linker Cancer

NH2-PEG4-Lys(Boc)-NH-(m-PEG24) is a cleavable 28 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136084

Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO)
ADC Linker Cancer

Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO) is a cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136130

N,N-Bis(PEG2-alkyne)-N-amido-PEG2-thiol	ADC Linker	Cancer
N,N-Bis(PEG2-alkyne)-N-amido-PEG2-thiol is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-126894

Bis-PEG9-acid	PROTAC Linker ADC Linker	Cancer
Bis-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG9-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-126893

Bis-PEG8-acid	PROTAC Linker ADC Linker	Cancer
Bis-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-141379

N-Bromoacetyl-β-alanine	PROTAC Linker ADC Linker	Cancer
N-Bromoacetyl-β-alanine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. N-Bromoacetyl-β-alanine is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W021787

NH2-PEG4-CH2CH2COOH
ADC Linker Cancer

NH2-PEG4-CH2CH2COOH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-15162

Monomethyl auristatin E MMAE; SGD-1010	Microtubule/Tubulin ADC Cytotoxin Apoptosis	Cancer
Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types.

HY-126892

Bis-PEG7-acid	PROTAC Linker ADC Linker	Cancer
Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-15579B

MMAF sodium Monomethylauristatin F sodium	Microtubule/Tubulin ADC Cytotoxin	Cancer
MMAF sodium (Monomethylauristatin F sodium) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF sodium (Monomethylauristatin F sodium) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A.

HY-15579A

MMAF Hydrochloride Monomethylauristatin F Hydrochloride	Microtubule/Tubulin ADC Cytotoxin	Cancer
MMAF Hydrochloride (Monomethylauristatin F Hydrochloride) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF Hydrochloride (Monomethylauristatin F Hydrochloride) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A.

HY-126668

Mal-PEG4-VC-PAB-DMEA	ADC Linker	Cancer
Mal-PEG4-VC-PAB-DMEA is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-VC-PAB-DMEA is used in the synthesis of antibody-drug conjugates (ADCs).

HY-15579

MMAF Monomethylauristatin F	Microtubule/Tubulin ADC Cytotoxin	Cancer
MMAF (Monomethylauristatin F) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin and SGN-CD19A.

HY-126672

Mal-PEG4-Val-Cit-PAB	ADC Linker	Cancer
Mal-PEG4-Val-Cit-PAB is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-Val-Cit-PAB is used in the synthesis of antibody-drug conjugates (ADCs).

HY-111012

DBCO-(PEG)3-VC-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
DBCO-(PEG)3-VC-PAB-MMAE is made by MMAE conjugated to DBCO-(PEG)3-vc-PAB linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.

HY-128946

CL2A-SN-38	Drug-Linker Conjugates for ADC	Cancer Inflammation/Immunology
CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A is a nonclaevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond.

HY-126674

Mal-Phe-C4-Val-Cit-PAB-DMEA	ADC Linker	Cancer
Mal-Phe-C4-Val-Cit-PAB-DMEA is a cleavable ADC linker containing a Maleimide group. Mal-Phe-C4-Val-Cit-PAB-DMEA is used for making antibody-drug conjugate.

HY-136288

Azide-PEG4-VC-PAB-Doxorubicin	Drug-Linker Conjugates for ADC	Cancer
Azide-PEG4-VC-PAB-Doxorubicin is a drug-linker conjugate composed of a cytotoxic anthracycline antibiotic Doxorubicin and a linker Azide-PEG4-VC-PAB to make antibody drug conjugate (ADC).

HY-117409

Aminoethyl-SS-ethylalcohol	PROTAC Linker ADC Linker	Cancer
Aminoethyl-SS-ethylalcohol (Compound 3) is an Alkyl-Chain-based PROTAC linker can be used in the synthesis of PROTACs. Aminoethyl-SS-ethylalcohol is also a glutathione cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-101157

Propargyl-PEG5-acid	ADC Linker	Cancer
Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3.

HY-118808

Propargyl-PEG2-NHBoc	ADC Linker PROTAC Linker	Cancer
Propargyl-PEG2-NHBoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-126673

Mal-C2-Gly3-EDA
ADC Linker Cancer

Mal-C2-Gly3-EDA is a cleavable ADC linker containing a Maleimide group. Mal-C2-Gly3-EDA is used for making antibody-drug conjugate.

HY-136297

DGN549-C	Drug-Linker Conjugates for ADC	Cancer
DGN549-C consists a cleavable ADC linker valine-alanine (va) and PBD dimer. DGN549 is a novel DNA-alkylating cytotoxic payload and can be used in the synthesis of antibody-drug conjugates (ADCs).

HY-117519

Amino-Tri-(carboxyethoxymethyl)-methane	ADC Linker PROTAC Linker	Cancer
Amino-Tri-(carboxyethoxymethyl)-methane is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(carboxyethoxymethyl)-methan is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-W008352

Boc-NH-PEG4-CH2CH2NH2
ADC Linker Cancer

Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133583

Propargyl-O-C1-amido-PEG3-C2-NHS ester	ADC Linker	Cancer
Propargyl-O-C1-amido-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W040257

NH2-PEG6-CH2CH2COOH
ADC Linker Cancer

NH2-PEG6-CH2CH2COOH is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130442

Mal-PEG2-acid	ADC Linker	Cancer
Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule.

HY-130387

Propargyl-PEG4-Tos	PROTAC Linker ADC Linker	Cancer
Propargyl-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W007713

Fmoc-8-amino-3,6-dioxaoctanoic acid Fmoc-NH-PEG2-CH2COOH	ADC Linker	Cancer
Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136129

N,N-Bis(PEG2-N3)-N-amido-PEG2-thiol
ADC Linker Cancer

N,N-Bis(PEG2-N3)-N-amido-PEG2-thiol is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-115545

DBCO-NHS ester 3	ADC Linker	Cancer
DBCO-NHS ester 3 (Compound 12) is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 3 is a derivative of Dibenzylcyclooctyne (DBCO) obtained by activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC).

HY-125586

β-Amanitin	DNA/RNA Synthesis ADC Cytotoxin	Cancer
β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs).

HY-126686

Mal-Phe-C4-VC-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
Mal-Phe-C4-VC-PAB-MMAE is made by MMAE conjugated to Mal-Phe-C4-VC-PAB linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.

HY-126976

Propargyl-PEG5-amine	ADC Linker PROTAC Linker	Cancer
Propargyl-PEG5-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-44234A

Fmoc-Gly-Gly-D-Phe-OtBu	ADC Linker	Cancer
Fmoc-Gly-Gly-D-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Gly-Gly-D-Phe-OtBu is the R-isomer of Fmoc-Gly-Gly-Phe-OtBu (HY-44234).

HY-131057

Mc-VC-PAB-SN38	Drug-Linker Conjugates for ADC	Cancer
Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs).

HY-126677

Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA	ADC Linker	Cancer
Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA is a double claevable 3-unit and 4-unit PEG linker for antibody-drug-conjugation (ADC).

HY-100216

SPDP SPDP Crosslinker	ADC Linker	Cancer
SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).

HY-130989

SuO-Glu-Val-Cit-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
SuO-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs).

HY-W051634

Propargyl-PEG2-amine	ADC Linker PROTAC Linker	Cancer
Propargyl-PEG2-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-141385

N-Succinimidyl 3-(Bromoacetamido)propionate 3-(2-Bromoacetamido)propanoic acid NHS ester	PROTAC Linker ADC Linker	Cancer
N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-Succinimidyl 3-(Bromoacetamido)propionate is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-21577

Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine	ADC Linker PROTAC Linker	Cancer
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-141382

Bromoacetamido-PEG4-acid	PROTAC Linker ADC Linker	Cancer
Bromoacetamido-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Bromoacetamido-PEG4-acid is also a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128945

CL2A	ADC Linker	Cancer Inflammation/Immunology
CL2A is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker.

HY-10581B

Gatifloxacin mesylate AM-1155 mesylate; BMS-206584 mesylate; PD135432 mesylate	Bacterial Topoisomerase Antibiotic	Infection
Gatifloxacin mesylate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin mesylate inhibits bacterial type II topoisomerases (IC₅₀=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC₅₀ = 0.109 μg/ml). Gatifloxacin mesylate can be used to treat bacterial conjunctivitis in vivo.

HY-P9926

Dupilumab REGN-668; SAR-231893	Interleukin Related	Inflammation/Immunology
Dupilumab (REGN-668) is a fully human mAb to IL-4 receptor α (IL-4Rα) that inhibits both IL-4 and IL-13 signaling, markedly improved moderate-to-severe atopic dermatitis.

HY-30105

N-Boc-piperazine
PROTAC Linker Cancer

N-Boc-piperazine is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183).

HY-140501

m-PEG11-acid	ADC Linker PROTAC Linker	Cancer
m-PEG11-acid is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG11-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-124386

DBCO-NHCO-PEG4-amine	ADC Linker	Cancer
DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE (HY-15162) and antibody (e.g., DBCO-VCpAB−MMAE and DBCO-TRX−MMAE with EC₅₀s of 280 nM and 22 nM in SKBR3 cells, respectively).

HY-140500

m-PEG10-acid	ADC Linker PROTAC Linker	Cancer
m-PEG10-acid is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG10-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-131056

Gly3-VC-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
Gly3-VC-PAB-MMAE consists a cleavable ADC linker (Gly3-VC-PAB) and a potent tubulin inhibitor (MMAE). Gly3-VC-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs).

HY-141395

m-PEG4-Boc	ADC Linker PROTAC Linker	Cancer
m-PEG4-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG4-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-140811

Azido-PEG3-maleimide	PROTAC Linker ADC Linker	Cancer
Azido-PEG3-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG3-maleimide is also a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130435

DBCO-PEG4-amine	ADC Linker	Cancer
DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker).

HY-126690

DBCO-(PEG2-VC-PAB-MMAE)2	Drug-Linker Conjugates for ADC	Cancer
DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.

HY-135122

DC10SMe	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
DC10SMe is a DNA alkylator, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC10SMe exhibits IC₅₀s of 15 pM, 12 pM, and 12 pM for Ramos, Namalwa, and HL60/s cancer cells, respectively.

HY-140215

Azido-PEG6-amine	PROTAC Linker ADC Linker	Cancer
Azido-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG6-amine is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-126918

THP-PEG6-OH	PROTAC Linker ADC Linker	Cancer
THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-140226

m-PEG10-amine	ADC Linker PROTAC Linker	Cancer
m-PEG10-amine is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG10-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-126951

Aminooxy-PEG2-alcohol	ADC Linker PROTAC Linker	Cancer
Aminooxy-PEG2-alcohol is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminooxy-PEG2-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-140004

Azide-PEG3-Tos	PROTAC Linker ADC Linker	Cancer
Azide-PEG3-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azide-PEG3-Tos is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-113931

Aminooxy-PEG2-azide	PROTAC Linker ADC Linker	Cancer
Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Aminooxy-PEG2-azide is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130537

Azido-PEG6-alcohol	PROTAC Linker ADC Linker	Cancer
Azido-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG6-alcohol is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130211

Azido-PEG5-alcohol	ADC Linker PROTAC Linker	Cancer
Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-141220

m-PEG12-OH	PROTAC Linker ADC Linker	Cancer
m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130946

NH2-C5-PEG4-N3-L-Lysine-PEG3-N3
ADC Linker Cancer

NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-140227

m-PEG12-amine	PROTAC Linker ADC Linker	Cancer
m-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG12-amine is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W039178

Hydroxy-PEG4-(CH2)2-Boc	ADC Linker	Cancer
Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 191).

HY-124123

Aminooxy-PEG4-alcohol	ADC Linker PROTAC Linker	Cancer
Aminooxy-PEG4-alcohol is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminooxy-PEG4-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-B0245S

Busulfan-D8	DNA Alkylator/Crosslinker Apoptosis
Busulfan-D8 is a deuterium labeled Busulfan. Busulfan is an alkyl sulfonate that acts as an alkylating antineoplastic agent. Busulfan forms both intra- and interstrand crosslinks on DNA. In mammals, Busulfan causes profound and prolonged reduction in the generation of hematopoietic progenitors without significantly affecting lymphocyte levels or humoral antibody responses.

HY-W008005

Amino-PEG4-alcohol	PROTAC Linker ADC Linker	Cancer
Amino-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG4-alcohol is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-114995

Tr-PEG2-OH	PROTAC Linker ADC Linker	Cancer Inflammation/Immunology
Tr-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Tr-PEG2-OH is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130426

Maleimido-tri(ethylene glycol)-propionic acid Mal-PEG3-acid	ADC Linker	Cancer
Maleimido-tri(ethylene glycol)-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Maleimido-tri(ethylene glycol)-propionic acid is used for the preparation of neolymphostin-based ADC precursors for site-specific cysteine mutant trastuzumab-A114C conjugation.

HY-130474

Azido-PEG6-NHS ester	ADC Linker PROTAC Linker	Cancer
Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs.

HY-120775

Boc-NH-PEG1-CH2CH2COOH	ADC Linker PROTAC Linker	Cancer
Boc-NH-PEG1-CH2CH2COOH is a cleavable (1 unit PEG) ADC linker and also a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of antibody-drug conjugates (ADCs) or PROTACs.

HY-140151

BCN-PEG3-Val-Cit	PROTAC Linker ADC Linker	Cancer
BCN-PEG3-Val-Cit is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. BCN-PEG3-Val-Cit is also a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130184

Azido-PEG8-NHS ester	ADC Linker PROTAC Linker	Cancer
Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-112560

Bis-PEG2-PFP ester	ADC Linker PROTAC Linker	Cancer
Bis-PEG2-PFP ester is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bis-PEG2-PFP ester is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-42488

Hydroxy-PEG3-(CH2)2-Boc	ADC Linker	Cancer
Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196).

HY-W067061

Hydroxy-PEG2-(CH2)2-Boc	ADC Linker	Cancer
Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196).

HY-122534

Mensacarcin	Mitochondrial Metabolism ADC Cytotoxin Apoptosis	Cancer
Mensacarcin, a highly complex polyketide, strongly inhibits cell growth universally in cancer cell lines and potently induces apoptosis in melanoma cells. Mensacarcin targets to mitochondria, affects energy metabolism in mitochondria, and activates caspase-dependent apoptotic pathways. Mensacarcin, an antibiotic, can be used as a cytotoxic component of antibody-drug conjugates (ADCs).

HY-128870

Mal-PEG2-VCP-Eribulin	Drug-Linker Conjugates for ADC	Cancer
Mal-PEG2-VCP-Eribulin consists the ADCs linker (Mal-PEG2-VCP) and Eribulin. Eribulin is a mechanistically unique microtubule inhibitor for cancer. Mal-PEG2-VCP-Eribulin is an Eribulin-based drug for antibody conjugates.

HY-140081

Boc-gly-PEG3-endo-BCN	PROTAC Linker ADC Linker	Cancer
Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Boc-gly-PEG3-endo-BCN is also a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-140150

Azido-PEG3-Val-Cit-PAB-PNP	ADC Linker PROTAC Linker	Cancer
Azido-PEG3-Val-Cit-PAB-PNP is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG3-Val-Cit-PAB-PNP is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-140149

Azido-PEG4-Val-Cit-PAB-OH	ADC Linker PROTAC Linker	Cancer
Azido-PEG4-Val-Cit-PAB-OH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-Val-Cit-PAB-OH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-126949

Aminooxy-PEG3-azide	ADC Linker PROTAC Linker	Cancer
Aminooxy-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminooxy-C2-PEG3-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-112900

DC41SMe	ADC Cytotoxin	Cancer
DC41SMe, a DC1 derivative, shows cytotoxicity in Ramos, Namalwa, and HL60/s cells with IC₅₀s ranging from 18-25 pM. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer.

HY-141218

m-PEG10-alcohol Decaethylene glycol monomethyl ether	ADC Linker PROTAC Linker	Cancer
m-PEG10-alcohol (Decaethylene glycol monomethyl ether) is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG10-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-130653

Azido-PEG4-C2-acid	PROTAC Linker ADC Linker	Cancer Inflammation/Immunology
Azido-PEG4-C2-acid a PEG-based PROTAC linker can be used in the synthesis of vRucaparib-TP4. Azido-PEG4-C2-acid is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136170

MC-SN38	Drug-Linker Conjugates for ADC	Cancer
MC-SN38 is a drug-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody drug conjugate (ADC). SN-38, an active metabolite of the Topoisomerase I inhibitor Irinotecan, inhibits DNA synthesis and causes frequent DNA single-strand breaks.

HY-130161

m-PEG4-Br	ADC Linker	Cancer
m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab (HY-P9907). m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency.

HY-130486

NH2-PEG6-Boc	PROTAC Linker ADC Linker	Cancer
NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-129637

NH2-PEG5-OH	PROTAC Linker ADC Linker	Cancer
NH2-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG5-OH is also a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-109714

3,4-Benzocoumarin	Others	Inflammation/Immunology
3,4-Benzocoumarin is a kind of the expanded structure of coumarin derivatives.Coumarin is a chemical compound in the benzopyrone chemical class that can be found in many natural species. Coumarins possess variety of biological activities and unique photophysical properties. 3,4-Benzocoumarin, a AOH‐like compound , has the sensibility of the antibody with an IC₅₀ of 919.2 ng/mL.

HY-126493

DM4-SPDP	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
DM4-SPDP is a drug-linker conjugate composed of a potent antitubulin agent DM4 and a linker SMCC to make antibody drug conjugate. SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

HY-P1439

RS 09	Toll-like Receptor (TLR)	Inflammation/Immunology
RS 09 is a TLR4 agonist. RS 09 promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. RS 09 acts as an adjuvant in vivo; RS 09 enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.

HY-130524

Amino-PEG4-CH2COOH	PROTAC Linker ADC Linker	Cancer
Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-15486

Salubrinal	Phosphatase HSV Autophagy Apoptosis	Cancer Infection Inflammation/Immunology
Salubrinal is a cell-permeable and selective inhibitor of eIF2α dephosphorylation. Salubrinal acts as a dual-specificity phosphatase 2 (Dusp2) inhibitor and suppresses inflammation in anti-collagen antibody-induced arthritis. Salubrinal has antiviral activity against HSV-1 and inhibits dephosphorylation of eIF2α mediated by the HSV-1 protein ICP34.5.

HY-130990

DBCO-PEG4-Val-Cit-PAB-MMAF	Drug-Linker Conjugates for ADC	Cancer
DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs).

HY-42618

Azido-PEG4-CH2-Boc	ADC Linker PROTAC Linker	Cancer
Azido-PEG4-CH2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-135124

DC44SMe	ADC Cytotoxin	Cancer
DC44SMe, a phosphate prodrug of cytotoxic DNA alkylator DC44, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC44SMe exhibits IC₅₀s of 2.0 nM, 2.8 nM, and 1.9 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC44SMe can be used for the targeted treatment of cancer.

HY-135123

DC4SMe	ADC Cytotoxin	Cancer
DC4SMe, a phosphate prodrug of cytotoxic DNA alkylator DC4, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4SMe exhibits IC₅₀s of 1.9 nM, 2.9 nM, and 1.8 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC4SMe can be used for the targeted treatment of cancer.

HY-129937

(S)-GNE-987	PROTAC Epigenetic Reader Domain	Cancer
(S)-GNE-987 (compound 4), the GNE-987 (a chimeric BET degrader) hydroxy-proline epimer, abrogates binding to VHL and does not degrade BRD4 protein. (S)-GNE-987 binds to the BRD4 BD1(IC₅₀=4 nM) and BD2 (3.9 nM) bromodomains and can be used to design PROTAC-Antibody Conjugate (PAC).

HY-P1439A

RS 09 TFA	Toll-like Receptor (TLR)	Inflammation/Immunology
RS 09 TFA is a TLR4 agonist. RS 09 TFA promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. RS 09 TFA acts as an adjuvant in vivo; RS 09 TFA enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.

HY-112615

NAMPT inhibitor-linker 1	Nampt Drug-Linker Conjugates for ADC	Cancer
NAMPT inhibitor-linker 1 is a drug-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-3 consists of an NAMPT inhibitor-linker 1 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressing cell lines such as GIST-T1 and NCI-H526 cells, with IC₅₀s of <3 pM and 9 pM, respectively.

HY-129942

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate	ADC Linker	Cancer
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes.

HY-112616

NAMPT inhibitor-linker 2	Nampt Drug-Linker Conjugates for ADC	Cancer
NAMPT inhibitor-linker 2 is a drug-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-4 consists of an NAMPT inhibitor-linker 2 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressing cell lines such as GIST-T1 and NCI-H526, with IC₅₀s of <7 pM and 40 pM, respectively.

HY-W040132

Boc-NH-PEG4-CH2CH2COOH	PROTAC Linker ADC Linker	Cancer
Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC).

HY-42149

NH2-PEG2-C2-Boc	PROTAC Linker ADC Linker	Cancer
NH2-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG2-C2-Boc is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-112898

DC1SMe	ADC Cytotoxin	Cancer
DC1Sme, a DC1 derivative, exhibits IC₅₀ values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively. DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin. DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer.

HY-136314

DBCO-PEG4-VC-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization.

HY-42490

N3-PEG3-CH2CH2COOH	PROTAC Linker ADC Linker	Cancer Inflammation/Immunology
N3-PEG3-CH2CH2COOH a PEG-based PROTAC linker can be used in the synthesis of BI-3663 (HY-111546), BI-4216 and BI-0319. Azido-PEG3-acid is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-P1279A

[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA	Neurokinin Receptor	Neurological Disease
[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA is a highly selective and potent NK₂ receptor agonist, with an IC₅₀ of 6.1 nM.

HY-42489

N3-PEG3-CH2CH2-Boc	ADC Linker PROTAC Linker	Cancer
N3-PEG3-CH2CH2-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-D1110

TFAX 594,SE	Others
TFAX 594,SE, an amine reactive red fluorescent dye, is insensitive to pH in the range 4-10. TFAX 594,SE forms bright and photostable conjugates with proteins and antibodies. TFAX 594,SE is suitable for use in flow cytometry, 2-photon excitation microscopy, and super resolution mircoscopy techniques, such as dSTORM. Excitation/emission maxima ~ 590 / 660 nm; extinction coefficient=92,000 M-1cm-1; quantum yield=0.66.

HY-D1111

TFAX 568, SE	Others
TFAX 568, SE, an amine reactive orange fluorescent dye, is insensitive to pH in the range 4-10. TFAX 568, SE forms bright and photostable conjugates with proteins and antibodies. TFAX 568, SE is suitable for use in flow cytometry, 2-photon excitation microscopy, and super resolution mircoscopy techniques, such as dSTORM. Excitation maximum=578 nm; emission maximum=602 nm; quantum yield=0.69; extinction coefficient=60720 M-1cm-1.

HY-140213

Azido-PEG2-C2-amine N3-PEG2-CH2CH2NH2	PROTAC Linker ADC Linker	Cancer
Azido-PEG2-C2-amine (N3-PEG2-CH2CH2NH2) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG2-C2-amine is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-120944

BAY-7598	MMP	Inflammation/Immunology
BAY-7598 is a potent, orally bioavailable, and selective MMP12 inhibitor probe with IC₅₀s of 0.085, 0.67 and 1.1 nM for human MMP12, murine MMP12, and rat MMP12, respectively.

HY-D1114

TFAX 488,SE dilithium	Others
TFAX 488,SE dilithium, an amine reactive green fluorescent dye, is insensitive to pH in the range 4-10. TFAX 488,SE dilithium forms bright and photostable conjugates with proteins and antibodies. TFAX 488,SE dilithium is suitable for use in flow cytometry, two-photon excitation microscopy (TPE), and super resolution microscopy techniques, such as dSTORM, SIM and STED. Excitation maximum=495 nm; emission maximum=515 nm; extinction coefficient=73,000 M-1cm-1; quantum yield=0.92.

HY-129937A

GNE-987	PROTAC Epigenetic Reader Domain	Cancer
GNE-987 is a highly active chimeric BET degrader. GNE-987 exhibits picomolar cell BRD4 degradation activity (DC₅₀=0.03 nM for EOL-1 AML cell line). GNE-987 binds equipotently to the BD1 and BD2 bromodomains of BRD4 with low nanomolar affinities (IC₅₀=4.7 and 4.4 nM, respectively). GNE-987 incorporates a potent BET binder/inhibitor, a VHL-binding fragment, and a ten methylene spacer moiety. GNE-987 can be used in PROTAC-Antibody Conjugate (PAC).

HY-D1113

TFAX 488,TFP	Others
TFAX 488,TFP, an amine reactive green fluorescent dye, is insensitive to pH in the range 4-10. TFAX 488,TFP forms bright and photostable conjugates with proteins and antibodies. TFAX 488,TFP is less susceptible to spontaneous hydrolysis during conjugation reactions compared to SE or NHS dyes. TFAX 488,TFP also displays greater stability compared to NHS and SE versions, typically lasting several hours. TFAX 488,TFP is suitable for use in flow cytometry, two-photon excitation microscopy (TPE), and super resolution microscopy techniques, such as dSTORM, SIM and STED. Excitation maximum=495 nm; emission maximum=515 nm; extinction coefficient=73,000 M-1cm-1; quantum yield=0.92.

Cat. No.	Product Name

HY-L023

Toxins for Antibody-Drug Conjugate Research Library

32 compounds

Antibody-Drug Conjugates (ADCs), a new class of treatment for cancer, are composed with a monoclonal antibody, a linker and a cytotoxic agent also referred to as a payload. To date, several ADCs have received market approval and more than 60 ADCs are currently in clinical trials. ADCs are one of the fastest growing classes of oncology drugs worldwide.

The payload or cytotoxic agent is the most important unit in the ADC. ADC has the capability to kill cancer cell depending on the potency of the payload. MCE provides 32 highly potent cytotoxins that contain auristatin derivatives, maytansinoids, calicheamicin, duocarmycin, pyrrolobenzodiazepines (PBDs), etc.

Cat. No.	Product Name	Type

HY-15943

6-TAMRA 6-Carboxytetramethylrhodamine	Fluorescent Dyes/Probes
6-TAMRA has been a widely used fluorophore for preparing bioconjugates, especially fluorescent antibody and avidin derivatives used in immunochemistry.

HY-D1052

Cy7-YNE
Fluorescent Dyes/Probes

Cy7-YNE is a fluorescence labeling agent (Ex=700-770 nm，Em=790 nm). Cyanine dyes are used to label proteins, antibodies, and peptides.

HY-D0825

CY7 Sulfo-Cyanine7	Fluorescent Dyes/Probes
Cy7 (Sulfo-Cyanine7) is a fluorescence labeling agent (Ex=750 nm, Em=773 nm). Cyanine dyes are used to label proteins, antibodies, peptides, and oligonucleotides.

HY-D0824

CY7-SE Sulfo-Cyanine7 Succinimidyl Ester	Fluorescent Dyes/Probes
CY7-SE (Sulfo-Cyanine7 Succinimidyl Ester) is a fluorescence labeling agent (Ex=700-770 nm，Em=790 nm). Cyanine dyes are used to label proteins, antibodies, peptides, and oligonucleotides.

HY-D0824A

CY7-SE triethylamine Sulfo-Cyanine7 Succinimidyl Ester triethylamine	Fluorescent Dyes/Probes
CY7-SE triethylamine (Sulfo-Cyanine7 Succinimidyl Ester triethylamine) is a fluorescence labeling agent (Ex=700-770 nm，Em=790 nm). Cyanine dyes are used to label proteins, antibodies, peptides, and oligonucleotides.

HY-D1049

DNP-X acid 6-((2,4-Dinitrophenyl)amino)hexanoic acid	Fluorescent Dyes/Probes
DNP-X acid (6-((2,4-Dinitrophenyl)amino)hexanoic acid), an amine-reactive building block for developing a probe, can be recognized by anti-DNP antibodies. DNP-X acid is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.

HY-D0926

Cy7.5	Protein Labeling
Cy7.5 is a fluorescence imaging (FI) agent (Ex=700-770 nm，Em=790 nm) as well as a magnetic resonance imaging (MRI) imaging agent. Cyanine dyes are used to label proteins, antibodies, peptides, and oligonucleotide.

HY-15941

5(6)-FITC Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers	Fluorescent Dyes/Probes
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of fluorescein dye that has wide-ranging applications as a label for antibodies and other probes, for use in fluorescence microscopy, flow cytometry and immunofluorescence-based assays such as Western blotting and ELISA.

HY-D1050

DNP-X, SE 6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester	Fluorescent Dyes/Probes
DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester), the DNP-X acid modified by succinimidyl ester, is an amine-reactive building block for developing a probe, which can be recognized by anti-DNP antibodies. DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester) is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.

Cat. No.	Product Name	Target	Research Area

HY-P2171

CCP peptide	Peptides	Inflammation/Immunology
CCP peptide is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA).

HY-P2171A

CCP peptide TFA	Peptides	Inflammation/Immunology
CCP peptide TFA is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide TFA functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA).

HY-P1783A

M2e, human TFA	Influenza Virus	Infection
M2e, human TFA, consisting of the 23 extracellular residues of M2 (the third integral membrane protein of influenza A), has been remarkably conserved in all human influenza A. M2e, human TFA is a valid and versatile vaccine candidate to protect against any strain of human influenza A.

HY-P9970

Infliximab Avakine; CT-P13	TNF Receptor	Metabolic Disease Inflammation/Immunology Neurological Disease
Infliximab (Avakine) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α. Infliximab has the potential for autoimmune, chronic inflammatory diseases and diabetic neuropathy research.

HY-P9920

Ramucirumab	VEGFR	Cancer
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D.

HY-41189

Fmoc-Val-Cit-PAB-PNP
ADC Linker Cancer

Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-P1449

Boc-Gly-Gly-Phe-Gly-OH	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-P1449A

Boc-Gly-Gly-Phe-Gly-OH TFA	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-P1787

β-Amyloid (4-10)	Amyloid-β	Neurological Disease
β-Amyloid (4-10) is an epitope for the polyclonal anti-Aβ(1-42) antibody, reduces amyloid deposition in a transgenic Alzheimer disease mouse model.

HY-P0223

FLAG peptide	Peptides	Inflammation/Immunology
FLAG peptide is an eight amino acids peptide (Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys) with an enterokinase-cleavage site; designed for antibody-mediated identification and purification of recombinant proteins.

HY-P1509

Rhodopsin Epitope Tag	Peptides	Neurological Disease
Rhodopsin Epitope Tag is a 9-amino acid peptide localized within the C-terminal region of bovine rhodopsin . Rhodopsin Epitope Tag is widely used as an epitope tag and can be recognized by a number of anti-rhodopsin antibodies.

HY-P0329

X-press Tag Peptide	Peptides	Others
X-press Tag Peptide is a tag peptide used for protein purification. X-press Tag is also an N-terminal leader peptide; this N-terminal peptide contains a polyhistidine sequence, the Xpress epitope (part of bacteriophage T7 gene 10 protein) and an enterokinase cleavage site. Anti-Xpress antibodies recognize the Xpress epitope sequence found in this leader peptide.

HY-P1439

RS 09	Toll-like Receptor (TLR)	Inflammation/Immunology
RS 09 is a TLR4 agonist. RS 09 promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. RS 09 acts as an adjuvant in vivo; RS 09 enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.

HY-P9900

Human IgG1 Control	Peptides	Others
Human IgG1 Control is purified from normal human serum through Protein G chromatography. Human IgG1 Control can be used as control, standard, blocking agent, or coating protein in a variety of assays, including ELISA, immunobloting (Western and Dot blots), immunoprecipitation, immunodiffusion, and immunoelectrophoresis. Human IgG1 Control may also be used as antigen or ligand in immunochemical conjugation reactions.

HY-P1279A

[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA	Neurokinin Receptor	Neurological Disease
[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA is a highly selective and potent NK₂ receptor agonist, with an IC₅₀ of 6.1 nM.

Cat. No.	Product Name

HY-K0221

Affinity Chromatography Column
MCE Affinity Chromatography (AC) Columns are designed for purification of recombinant proteins with different tags, enzymes, antibodies, antigens and nucleic acids.

HY-K0701

Antibody/Protein Labeling Kit – FITC
The Antibody/Protein Labeling Kit – FITC is used for protein fluorescent labeling. Spin Desalting Columns contained in this kit offer exceptional desalting for protein samples (>5 kDa).

HY-K1005

Ultra High Sensitivity ECL Kit
MCE Ultra High Sensitivity ECL Kit is an ultra-sensitive, luminol-based enhanced chemiluminescent substrate for detecting horseradish peroxidase (HRP) labeled antibodies on western blots.

Cat. No.	Product Name	Target	Research Area

HY-P9917

Tocilizumab Anti-Human IL6R, Humanized Antibody	Interleukin Related	Cancer Inflammation/Immunology
Tocilizumab (Anti-Human IL6R, Humanized Antibody) is an anti-human interleukin-6 receptor (IL-6R) neutralizing antibody, prevents binding of IL-6 to the IL-6R, thereby inhibiting both classic and trans-signaling. Tocilizumab (Anti-Human IL6R, Humanized Antibody) can be used for the treatment of rheumatoid arthritis. Tocilizumab is remarkablely effective for the study of severe COVID-19 (coronavirus disease).

HY-P9803

Anti-SARS-80R mAb SARS-80R; SARS Antibody-80R	SARS-CoV	Infection
Anti-SARS-80R mAb (SARS-80R) is a human monoclonal IgG1 antibody produced in CHO cells. Anti-SARS-80R mAb can specifically bind to Spike (S1) protein to prevent SARS virus infection of susceptible cells.

HY-P9801

Anti-Spike-RBD mAb SARS-CoV-2 (2019-nCoV) Spike RBD Antibody	SARS-CoV	Infection
Anti-Spike-RBD mAb is a CHO cell derived human monoclonal IgG1 antibody. Blocking the interaction of spike protein and ACE2 is a potential therapeutic approach for SARS-CoV-2 treatment.

HY-P9807

Anti-SARS-CoV-2 Spike mAb (CR3022) SARS-CR3022; SARS-CoV-2 Antibody-CR3022	SARS-CoV	Infection Inflammation/Immunology
Anti-SARS-CoV-2 Spike mAb (CR3022) is a a CHO cell derived human monoclonal IgG1 antibody. It binds to both S1 domain of SARS-CoV/SARS-CoV-2 Spike protein.

HY-P9805

Anti-MERS-3A1 mAb MERS-3A1; MERS Antibody-3A1	SARS-CoV	Infection
Anti-MERS-3A1 mAb (MERS-3A1) is a human monoclonal IgG1 antibody with the high binding affinity produced in CHO cells. Anti-MERS-3A1 mAb bocks the binding of MERS-CoV spike protein to DPP4 receptor.

HY-P9802

Anti-Spike-RBD Single Domain mAb SARS-CoV-2 (2019-nCoV) Single-Domain Antibodies; Humanized Single Domain Antibody	SARS-CoV	Infection
Anti-Spike-RBD Single Domain mAb is a CHO cell derived Alpaca monoclonal VHH-huFc antibody, specifically binds to SARS-CoV-2 RBD with high affinity.

HY-P9906

Bevacizumab
Anti-Human VEGF, Humanized Antibody
VEGFR Cancer

Bevacizumab, a humanized monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity.
HY-P9908

Adalimumab
Anti-Human TNF-alpha, Human Antibody
TNF Receptor Inflammation/Immunology

Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).
HY-P9909

Ustekinumab
Anti-Human IL-12/IL-23, Human Antibody
Interleukin Related Inflammation/Immunology

Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.

HY-P9907

Trastuzumab Anti-Human HER2, Humanized Antibody	EGFR	Cancer
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has the potential for HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer research.

HY-P9913

Rituximab Anti-Human CD20 type I, Chimeric Antibody	Inhibitory Antibodies	Cancer Inflammation/Immunology
Rituximab is an anti-CD20 chimeric monoclonal antibody used to treat certain autoimmune diseases and types of cancer.

HY-108730

Avelumab Anti-Human PD-L1, Human Antibody; MSB 0010718C; MSB0010718C	PD-1/PD-L1	Cancer Inflammation/Immunology
Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity.

HY-P9911

Vedolizumab Anti-Human lymphocyte α4β7 integrin, Humanized Antibody	Integrin	Inflammation/Immunology
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease.

HY-P9910

Obinutuzumab GA101; Anti-Human CD20 type II, Humanized Antibody	Inhibitory Antibodies	Cancer
Obinutuzumab (GA101) a novel glycoengineered Type II CD20 monoclonal antibody in development for non-Hodgkin lymphoma.

HY-P9804

Anti-MERS-2E6 mAb MERS-2E6; MERS Antibody-2E6	SARS-CoV	Infection
Anti-MERS-2E6 mAb (MERS-2E6; MERS Antibody-2E6), a human neutralizing antibody IgG1 (CHO expressed) that can compete for the binding of the virus Spike protein to the receptor (CD26), thereby inhibiting virus invasion into host cells.

HY-P9806

Anti-MERS-D12 mAb MERS-D12; MERS Antibody-D12	SARS-CoV	Infection
Anti-MERS-D12 mAb (MERS-D12; MERS Antibody-D12) is a human monoclonal IgG1. Anti-MERS-D12 mAb binds directly to the DPP4 interacting region of the MERS-CoV Spike receptor binding domain (RBD) and effect neutralization by directly blocking receptor binding.

HY-P9902

Pembrolizumab
MK-3475; Lambrolizumab
PD-1/PD-L1 Cancer

Pembrolizumab is a humanized antibody inhibiting the programmed cell death 1 (PD-1) receptor, used in cancer immunotherapy.

HY-P9923

Benralizumab MEDI-563; BIW-8405	Interleukin Related	Inflammation/Immunology
Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma.

HY-P9919

Durvalumab MEDI 4736	PD-1/PD-L1	Cancer
Durvalumab (MEDI 4736) is an humanized anti-PD-L1 monoclonal antibody. Durvalumab (MEDI4736) completely blocks the binding of PD-L1 to both PD-1 and CD80, with IC₅₀s of 0.1 and 0.04 nM, respectively.

HY-P9912

Pertuzumab
EGFR Cancer

Pertuzumab, a humanized monoclonal antibody, is a HER2 dimerization inhibitor for the treatment of metastatic HER2-positive breast cancer.
HY-P9904

Atezolizumab
MPDL3280A
PD-1/PD-L1 Cancer

Atezolizumab is a selective humanized monoclonal IgG1 antibody against programmed death ligand 1 (PD-L1), used for cancer research.

HY-P9903

Nivolumab BMS-936558; ONO-4538; MDX-1106	PD-1/PD-L1	Cancer
Nivolumab is a programmed death receptor-1 (PD-1) blocking antibody to treat advanced (metastatic) non-small cell lung cancer.

HY-P9905

Cetuximab C225	EGFR	Cancer
Cetuximab (C225) is a monoclonal antibody that inhibits epidermal growth factor receptor (EGFR), with a K_d of 0.201 nM for soluble EGFR by SPR. Cetuximab has potent antitumor activity.

HY-P9901

Ipilimumab MDX-010; BMS-734016	Inhibitory Antibodies	Cancer
Ipilimumab is a fully human monoclonal IgG1κ antibody against the cytotoxic T-lymphocyte antigen-4 (CTLA-4), an immune-inhibitory molecule expressed in activated T cells and in suppressor T regulatory cells.

HY-P9970

Infliximab Avakine; CT-P13	TNF Receptor	Metabolic Disease Inflammation/Immunology Neurological Disease
Infliximab (Avakine) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α. Infliximab has the potential for autoimmune, chronic inflammatory diseases and diabetic neuropathy research.

HY-108831

Natalizumab	Integrin	Inflammation/Immunology
Natalizumab is a recombinant, humanized monoclonal antibody, binds to α4β1-integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1). Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses.

HY-P9920

Ramucirumab	VEGFR	Cancer
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D.

HY-P9949

Reslizumab Sch 55700	Interleukin Related	Inflammation/Immunology
Reslizumab (Sch 55700) is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. Reslizumab is effective in neutralizing the function of IL-5. Reslizumab inhibits IL-5-dependent cell proliferation, with an IC₅₀ value of approximately 91.1pM. Reslizumab has high binding affinity for human IL-5, with K_D values of 109 pM and 4.3 pM in the the Biacore surface plasmon resonance and Kinetic Exclusion Assay, respectively.

HY-10581B

Gatifloxacin mesylate AM-1155 mesylate; BMS-206584 mesylate; PD135432 mesylate	Bacterial Topoisomerase Antibiotic	Infection
Gatifloxacin mesylate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin mesylate inhibits bacterial type II topoisomerases (IC₅₀=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC₅₀ = 0.109 μg/ml). Gatifloxacin mesylate can be used to treat bacterial conjunctivitis in vivo.

HY-P9926

Dupilumab REGN-668; SAR-231893	Interleukin Related	Inflammation/Immunology
Dupilumab (REGN-668) is a fully human mAb to IL-4 receptor α (IL-4Rα) that inhibits both IL-4 and IL-13 signaling, markedly improved moderate-to-severe atopic dermatitis.

HY-30105

N-Boc-piperazine
PROTAC Linker Cancer

N-Boc-piperazine is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183).

HY-108829

Abatacept CTLA4lg; BMS-188667	Inhibitory Antibodies	Inflammation/Immunology
Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains). Abatacept is a selective T-cell co-stimulation modulator and a protein drug for the autoimmune diseases.

HY-P9900

Human IgG1 Control	Inhibitory Antibodies	Others
Human IgG1 Control is purified from normal human serum through Protein G chromatography. Human IgG1 Control can be used as control, standard, blocking agent, or coating protein in a variety of assays, including ELISA, immunobloting (Western and Dot blots), immunoprecipitation, immunodiffusion, and immunoelectrophoresis. Human IgG1 Control may also be used as antigen or ligand in immunochemical conjugation reactions.

HY-P1279A

[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA	Neurokinin Receptor	Neurological Disease
[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA is a highly selective and potent NK₂ receptor agonist, with an IC₅₀ of 6.1 nM.

Cat. No.	Product Name	Target	Category

HY-118870

γ-Globulins from human blood	Endogenous Metabolite	Acids and Aldehydes
γ-Globulins from human blood are a class of proteins in the blood. γ-Globulin is a protein fraction of blood serum containing many antibodies that protect against bacterial and viral infectious diseases. γ-Globulins from human blood is used for common variable immunodeficiency

HY-N3522

Platycoside E	Others	Terpenoids and Glycosides
Platycoside E is a platycodigenin-type saponin isolated from the root of Platycodon grandiflorum with haemolytic activity and adjuvant potential. Platycoside E promotes the production of the sera OVA-specific IgG2a and IgG2b antibody in the ovalbumin (OVA)-immunized mice.

HY-17422

Acyclovir Aciclovir; Acycloguanosine	HSV Bacterial Antibiotic Apoptosis	Saccharides and Glycosides Alkaloids
Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC₅₀ of 0.85 μM), HSV-2 (IC₅₀ of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia.

HY-P0223

FLAG peptide	Others	Acids and Aldehydes
FLAG peptide is an eight amino acids peptide (Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys) with an enterokinase-cleavage site; designed for antibody-mediated identification and purification of recombinant proteins.

Cat. No.	Product Name	Species	Source

HY-P9806

Anti-MERS-D12 mAb MERS-D12; MERS Antibody-D12		CHO
Anti-MERS-D12 mAb is a human monoclonal IgG1. It binds directly to the DPP4 interacting region of the MERS-CoV Spike receptor binding domain (RBD) and effect neutralization by directly blocking receptor binding.

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