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Results for "

B12

" in MedChemExpress (MCE) Product Catalog:

28

Inhibitors & Agonists

1

Fluorescent Dye

2

Biochemical Assay Reagents

1

MCE Kits

15

Natural
Products

3

Recombinant Proteins

5

Isotope-Labeled Compounds

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0315
    Vitamin B12
    2 Publications Verification

    Cyanocobalamin

    Endogenous Metabolite Metabolic Disease Cancer
    Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood .
    Vitamin <em>B12</em>
  • HY-112790

    Coenzyme B12; Cobamamide; AdoCbl

    Endogenous Metabolite Metabolic Disease
    Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B12 which is a cofactor for methylmalonyl CoA mutase
    Adenosylcobalamin
  • HY-B2209
    Hydroxocobalamin
    1 Publications Verification

    Vitamin B12a

    Endogenous Metabolite Metabolic Disease
    Hydroxocobalamin (Vitamin B12a) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .
    Hydroxocobalamin
  • HY-B0315A

    Endogenous Metabolite Metabolic Disease
    Biotin-Vitamin B12 is the biotinylated Vitamin B12. Vitamin B12 is a vitamin that plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood .
    Biotin-Vitamin <em>B12</em>
  • HY-B2209C

    Vitamin B12a hydrochloride

    Endogenous Metabolite Metabolic Disease
    Hydroxocobalamin hydrochloride is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the research of vitamin B12 deficiency including pernicious anemia .
    Hydroxocobalamin hydrochloride
  • HY-B0586
    Methylcobalamin
    1 Publications Verification

    Mecobalamin; CH3-B12

    Endogenous Metabolite Metabolic Disease
    Methylcobalamin (CH3-B12), a cobalamin, is a form of vitamin B12.
    Methylcobalamin
  • HY-B0315S

    Endogenous Metabolite Metabolic Disease
    Vitamin B12- 13C7 is the 13C-labeled Vitamin B12. Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood[1][2].
    Vitamin <em>B12</em>-13C7
  • HY-B2209B
    Hydroxocobalamin acetate
    1 Publications Verification

    Vitamin B12a acetate

    Endogenous Metabolite Metabolic Disease
    Hydroxocobalamin acetate is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the research of vitamin B12 deficiency including pernicious anemia .
    Hydroxocobalamin acetate
  • HY-B2209A
    Hydroxocobalamin monohydrochloride
    1 Publications Verification

    Vitamin B12a monohydrochloride

    Endogenous Metabolite Metabolic Disease
    Hydroxocobalamin monohydrochloride (Vitamin B12a monohydrochloride) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .
    Hydroxocobalamin monohydrochloride
  • HY-B2209BR

    Vitamin B12a acetate (Standard)

    Endogenous Metabolite Metabolic Disease
    Hydroxocobalamin (acetate) (Standard) is the analytical standard of Hydroxocobalamin (acetate). This product is intended for research and analytical applications. Hydroxocobalamin acetate is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the research of vitamin B12 deficiency including pernicious anemia .
    Hydroxocobalamin acetate (Standard)
  • HY-103395
    Methylmalonic acid
    1 Publications Verification

    Methylpropanedioic acid; Methylmalonate

    Endogenous Metabolite Cancer
    Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer.
    Methylmalonic acid
  • HY-W040821
    DL-Homocysteine
    2 Publications Verification

    Endogenous Metabolite Neurological Disease
    DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. DL-Homocysteine is correlated with Vitamin B12, renal functions and folate levels, affects the cross-sectional cognition indirectly through white matter microstructural integrity .
    DL-Homocysteine
  • HY-103395R

    Methylpropanedioic acid (Standard); Methylmalonate (Standard)

    Endogenous Metabolite Cancer
    Methylmalonic acid (Standard) is the analytical standard of Methylmalonic acid. This product is intended for research and analytical applications. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer.
    Methylmalonic acid (Standard)
  • HY-133739

    RAR/RXR Cancer
    NBD-125 (B-12), a berberine analogue, is an RXRα activator, with an IC50 of 31.10 μM in KM12C cell .
    NBD-125
  • HY-103395S

    Methylpropanedioic acid-d3; Methylmalonate-d3

    Endogenous Metabolite Cancer
    Methylmalonic acid-d3 is the deuterium labeled Methylmalonic acid. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[1][2].
    Methylmalonic acid-d3
  • HY-103395S1

    Endogenous Metabolite Cancer
    Methylmalonic acid- 13C4 is the 13C labeled Methylmalonic acid[1]. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[2].
    Methylmalonic acid-13C4
  • HY-17016S

    GS 4104-d5 phosphate

    Isotope-Labeled Compounds Influenza Virus Infection
    Oseltamivir-d5 (phosphate) is the deuterium labeled Oseltamivir phosphate. Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B[1][2].
    Oseltamivir-d5 phosphate
  • HY-137808

    Succinyl-CoA sodium

    Endogenous Metabolite Neurological Disease Metabolic Disease
    Succinyl-Coenzyme A (Succinyl-CoA) sodium is an intermediate of the citric acid cycle. Succinyl-Coenzyme A sodium can be converted to succinic acid and can also combines with glycine to form δ-ALA to synthesize porphyrins (heme). Succinyl-Coenzyme A sodium can be used in the study of metabolic, neurological and haematological abnormalities (such as porphyrias) caused by nutritional vitamin B12 deficiency (resulting in a deficiency in Succinyl-Coenzyme A synthesis) .
    Succinyl-Coenzyme A sodium
  • HY-154992

    F2PhEtyCbl

    Others Others
    2,4-Difluorophenylethynylcobalamin is a potential B12 antivitamin via binding to human B12 -processing enzyme CblC with high affinity (KD=130 nm). 2,4-Difluorophenylethynylcobalamin withstood tailoring by CblC, and stabilizes the ternary complex with the cosubstrate glutathione (GSH) . 2,4-Difluorophenylethynylcobalamin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    2,4-Difluorophenylethynylcobalamin
  • HY-156796

    ADC Cytotoxin Neurological Disease Cancer
    Akt/ROCK-IN-1 (B12) is a dual inhibitor for Akt and ROCK, with the IC50s of 0.023 nM and 1.47 nM, respectively. Akt/ROCK-IN-1 has antitumor activity for neuroblastoma .
    Akt/ROCK-IN-1
  • HY-149615

    Fungal Infection
    Antibacterial agent 157 (compound B12) is a fungicidal agent. Antibacterial agent 157 can influence the protein synthesis of Botrytis cinerea. Antibacterial agent 157 can be used for gray mold resistance control research .
    Antibacterial agent 157
  • HY-126791

    Isosuccinyl coenzyme A; Methylmalonyl coenzyme A

    Endogenous Metabolite Others
    Methylmalonyl coenzyme A (Methylmalonyl-CoA) is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl coenzyme A tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12 .
    Methylmalonyl-CoA
  • HY-126791A

    Isosuccinyl coenzyme A tetralithium; Methylmalonyl coenzyme tetralithium

    Endogenous Metabolite Others
    Methylmalonyl-CoA (Methylmalonyl coenzyme A) tetralithium is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl-CoA tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12 .
    Methylmalonyl-CoA tetralithium
  • HY-W127737

    Mecobalamin hydrate

    Biochemical Assay Reagents Others
    Methylcobalamin Hydrate is a coenzyme required for methionine biosynthesis. Vitamins (hematopoiesis). It acts as a histamine receptor, Alzheimer study. Methylcobalamin is also used in the research of peripheral neuropathy, diabetic neuropathy, and as an initial research for amyotrophic lateral sclerosis. It can be used to prevent or research pathologies caused by vitamin B12 deficiency, such as pernicious anemia.
    Methylcobalamin hydrate
  • HY-115980

    Apoptosis Cancer
    Anticancer agent 39 (compound B12), a fluorescent derivative of Jiyuan Oridonin A (JOA), induces the collapse of mitochondrial membrane potential (MMP)and thus induced apoptosis.Anticancer agent 39 inhibits cell cloning and migration.Anticancer agent 39 exhibits promising anti-proliferative activity against HGC-27 cells with IC50 value of 0.39 μM .
    Anticancer agent 39
  • HY-144761

    JNK Cancer
    TOPK-p38/JNK-IN-1 (Compound B12) is an orally active TOPK-p38/JNK signaling pathway inhibitor with the IC50 value of 2.14 µM for NO production. TOPK-p38/JNK-IN-1 shows anti-inflammatory activities. TOPK-p38/JNK-IN-1 also inhibits phosphorylate downstream related proteins and avoids degradation of TOPK .
    TOPK-p38/JNK-IN-1
  • HY-RS06392

    Small Interfering RNA (siRNA) Others
    HSD17B12 Human Pre-designed siRNA Set A contains three designed siRNAs for HSD17B12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    HSD17B12 Human Pre-designed siRNA Set A
    HSD17B12 Human Pre-designed siRNA Set A
  • HY-B0822S1

    GABA Receptor Cytochrome P450 Inflammation/Immunology
    Fipronil- 13C6 is the 13C-labeled Fipronil. Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.
    Fipronil-13C6

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