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BCX1777

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16210
    Forodesine
    10+ Cited Publications

    BCX-1777; Immucillin-H

    		 Nucleoside Antimetabolite/Analog Apoptosis Cancer
    Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels .
    Forodesine
  • HY-16209
    Forodesine hydrochloride
    10+ Cited Publications

    BCX-1777 hydrochloride; Immucillin-H hydrochloride

    		 Nucleoside Antimetabolite/Analog Apoptosis Cancer
    Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels .
    Forodesine hydrochloride

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