Search Result
Results for "
Biotin
" in MedChemExpress (MCE) Product Catalog:
51
Biochemical Assay Reagents
3
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-B0511
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Biotin
Maximum Cited Publications
8 Publications Verification
Vitamin B7; Vitamin H; D-Biotin
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Endogenous Metabolite
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Metabolic Disease
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Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .
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- HY-P2549
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- HY-P2551
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Amyloid-β
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Neurological Disease
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Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-ß-(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via post-translational processing of amyloid precursor protein (APP) .
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- HY-140656F
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Fluorescent Dye
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Others
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Biotin-PEG-Biotin (MW 20000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity.
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- HY-D1669
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Fluorescent Dye
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Others
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Biotin-11-UTP is a Biotin-labeled uridine triphosphate (UTP), containing 11 atoms in the linker between biotin and UTP. Biotin-11-UTP can biotinylate transcribed RNA in vitro and has been widely used as labeling RNA probe . Biotin-11-UTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-145445
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- HY-157221
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- HY-151714
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ADC Linker
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Others
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Biotin-MeTz shiyi is a click chemistry reagent with a terminal methyltetrazine group. Biotin-MeTz shiyi, as a biotin derivative, can be used for the preparation of biotinylated conjugates .
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- HY-147206A
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Fluorescent Dye
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Others
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Biotin-PEG-Alk (MW 1000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 1000) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-147206B
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Fluorescent Dye
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Others
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Biotin-PEG-Alk (MW 2000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 2000) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-147206C
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Fluorescent Dye
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Others
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Biotin-PEG-Alk (MW 3400) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 3400) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-147206E
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Fluorescent Dye
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Others
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Biotin-PEG-Alk (MW 10000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 10000) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-147206F
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Fluorescent Dye
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Others
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Biotin-PEG-Alk (MW 20000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 20000) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-P2546
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Neurokinin Receptor
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Neurological Disease
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Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .
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- HY-156381
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Biochemical Assay Reagents
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Others
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Biotin-PEG3-CoenzymeA is a non cell-permeable substrate based on biotin with a PEG linker. Biotin-PEG3-CoenzymeA can be used for biotinylation of living cells, Labeling in solution, interaction studies .
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- HY-141898
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Fluorescent Dye
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Others
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Biotin-4-aminophenol is a biotin-phenol analog. Biotin-4-aminophenol generates free radicals and conjugates to tyrosine residues in proteins more efficiently and selectively than the previously reported BP1 .
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- HY-154801
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Others
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Others
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Biotin-PEG3-CONH-Ph-CF3-diazirine is a biotin labeled PEG3 derivative. Biotin-PEG3-CONH-Ph-CF3-diazirine can be used for protein labeling .
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- HY-P3576
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Fluorescent Dye
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Neurological Disease
Cancer
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Biotin-Gastrin Releasing Peptide, human is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .
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- HY-D1635
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Biotin-XX-SSE
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Fluorescent Dye
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Infection
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Sulfo-NHS-LC-LC-Biotin (Biotin-XX-SSE), a biotin reagent, is used to label the proteins exposed to the external leaflet of intact exosomes and contains a larger spacer arm between the biotin and amine reactive linker. The size of this linker helps to overcome steric hindrance and increases labeling efficiency at the crowded exosome surface .
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- HY-130490
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PROTAC Linkers
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Cancer
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Biotin-bis-amido-SS-NHS is an Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-130143
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PROTAC Linkers
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Cancer
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Biotin-PEG3-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-W250928C
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Carbamic acid, N-(17-azido-3,6,9,12,15-pentaoxaheptadec-1-yl)-, 1,1-dimethylethyl ester
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Fluorescent Dye
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Others
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Biotin-PEG-azide (MW 2000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; azide, is a moderately good leaving group, can react with alkyne by Cu-catalyzation, which improve the efficiency of biotin binding targets.
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- HY-W250928D
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Carbamic acid, N-(17-azido-3,6,9,12,15-pentaoxaheptadec-1-yl)-, 1,1-dimethylethyl ester
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Fluorescent Dye
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Others
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Biotin-PEG-azide (MW 3400) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; azide, is a moderately good leaving group, can react with alkyne by Cu-catalyzation, which improve the efficiency of biotin binding targets.
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- HY-P2136F
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Apoptosis
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Neurological Disease
Inflammation/Immunology
Cancer
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Biotin-COG1410 TFA is a biotin labled COG1410 (HY-P2136). COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological disease .
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- HY-D0802
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Biotin-NHS; Biotin N-hydroxysuccinimide ester; NHS-Biotin
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Fluorescent Dye
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Others
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Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.
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- HY-141793
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- HY-140656A
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PROTAC Linkers
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Cancer
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Biotin-PEG-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140902A
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PROTAC Linkers
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Cancer
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Biotin-PEG3-C3-NH2 is a PEG-based PROTAC linker, with NH2 functional group, that can be used in the synthesis of PROTACs .
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- HY-D1022
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Biotin-16-deoxyuridine-5'-triphosphate
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Fluorescent Dye
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Others
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Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-140656
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PROTAC Linkers
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Cancer
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Biotin-PEG-Biotin (MW 1000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140656B
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PROTAC Linkers
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Cancer
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Biotin-PEG-Biotin (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140656C
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PROTAC Linkers
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Cancer
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Biotin-PEG-Biotin (MW 3400) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140656D
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PROTAC Linkers
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Cancer
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Biotin-PEG-Biotin (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140656E
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PROTAC Linkers
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Cancer
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Biotin-PEG-Biotin (MW 10000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-114776
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Fluorescent Dye
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Others
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Biotin-olefin (Compound 1) is a biotin probe. Biotin-olefin can used for photoimmobilization on thiol-functionalized surfaces .
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- HY-113268
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- HY-135641
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Fluorescent Dye
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Others
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Biotin-probe 1 is a non-radiolabeled probe. Biotin-labeled probes can be applied to in situ hybridization .
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- HY-D1022A
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Biotin-16-deoxyuridine-5'-triphosphate trisodium
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DNA Stain
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Others
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Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-156197
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- HY-D1686
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DNA Stain
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Others
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Biotin-16-UTP is an active substrate for RNA polymerase. Biotin-16-UTP can replace UTP in the in vitro transcription reaction for RNA labeling .
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- HY-D1029
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- HY-152965
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- HY-125501
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Biotin-(AC5)2-hydrazide
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Biochemical Assay Reagents
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Others
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Biotin-XX hydrazide (Biotin-(AC5)2-hydrazide) is a carbonyl-reactive biotinylation reagent which contains two aminohexanoic acid spacers. Biotin-XX hydrazide has higher efficiency of avidin-binding .
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- HY-D1668
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DNA Stain
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Others
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Biotin-11-dCTP is a fluorescent dye for DNA labeling . Biotin-11-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-D1686B
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DNA Stain
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Others
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Biotin-16-UTP tetrasodium is an active substrate for RNA polymerase. Biotin-16-UTP tetrasodium can replace UTP in the in vitro transcription reaction for RNA labeling .
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- HY-D1029A
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- HY-146244A
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Toll-like Receptor (TLR)
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Inflammation/Immunology
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Biotin-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. Biotin-labeled Agatolimod (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
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- HY-100894
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Caspase
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Cancer
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Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates.
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- HY-116027
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PROTAC Linkers
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Cancer
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Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140492
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PROTAC Linkers
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Cancer
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Biotin-PEG8-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140493
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PROTAC Linkers
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Cancer
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Biotin-PEG12-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-D0980
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Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin
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Biochemical Assay Reagents
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Metabolic Disease
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Biotin-DADOO is a biotinylation reagent, which can be used to synthesize a biotin-estradiol conjugate (i.e., biotin-DADOO-estradiol) to develop a direct, broad range enzyme immunoassay to measure plasma estradiol concentrations.
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- HY-139912
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DNA Stain
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Others
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Biotin-aniline is a probe with substantially high reactivity towards RNA and DNA. Biotin-aniline emerges as more efficient probe for capturing subcellular transcriptome in living cells with high spatial specificity .
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- HY-111879
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SNIPERs
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Cancer
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Biotin-BS contains two different ligands, methyl-bestatin (MeBS) for cIAP1 and biotin, which are connected by linkers. MeBS as a ligand for cellular inhibitor of apoptosis protein 1 (cIAP1) ubiquitin ligase .
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- HY-147205B
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- HY-150751A
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Toll-like Receptor (TLR)
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Inflammation/Immunology
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Biotin-labeled ODN TTAGGG (sodium), a inhibitory oligonucleotide (ODN), is a TLR9, AIM2 and cGAS antagonist. Biotin-labeled ODN TTAGGG (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
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- HY-P1264F1
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nAChR
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Neurological Disease
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Biotin-α-Bungarotoxin is the Biotin labelled α-Bungarotoxin (HY-P1264). α-Bungarotoxin is a competitive antagonist at nicotinic acetylcholine receptors (nAChRs) .
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- HY-P2467
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Fluorescent Dye
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Metabolic Disease
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Biotin-TAT (47-57), a biotin tagged TAT, is a transactivator of transcription. Biotin-TAT (47-57) is one of the most widely used protein transduction domains (PTDs) into different primary cells is ATP- and temperature-dependent, indicating the involvement of endocytosis .
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- HY-D1839
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Biotin Tyramide
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Fluorescent Dye
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Others
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Biotin TSA(200×) (Biotin Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-140888
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PROTAC Linkers
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Cancer
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Biotin-PEG2-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140889
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PROTAC Linkers
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Cancer
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Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140893
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PROTAC Linkers
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Cancer
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Biotin-PEG6-alcohol is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140895
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PROTAC Linkers
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Cancer
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Biotin-PEG4-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140896
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PROTAC Linkers
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Cancer
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Biotin-PEG5-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140899
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PROTAC Linkers
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Cancer
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Biotin-PEG8-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140900
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PROTAC Linkers
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Cancer
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Biotin-PEG11-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140907
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PROTAC Linkers
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Cancer
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Biotin-PEG3-Mal is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140908
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PROTAC Linkers
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Cancer
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Biotin-PEG6-Mal is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140932
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PROTAC Linkers
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Cancer
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Biotin-PEG4-hydrazide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140943
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PROTAC Linkers
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Cancer
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Biotin-PEG7-thiourea is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138749
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PROTAC Linkers
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Cancer
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Biotin alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-100215
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- HY-145152
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PROTAC Linkers
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Others
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Biotin-Thalidomide is a cereblon affinity probe for PROTAC and targeted protein degradation research.
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- HY-B0511A
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Vitamin B7 sodium; Vitamin H sodium; D-Biotin sodium
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Endogenous Metabolite
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Metabolic Disease
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Biotin (Vitamin B7) sodium is a water-soluble B vitamin and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin sodium is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .
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- HY-147206
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Fluorescent Dye
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Others
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Biotin-PEG-Alk (MW 600) is a Biotin-labeled Alkyne functionalized polyethylene glycol. Biotin-PEG-Alk (MW 600) can be used to modify proteins, peptides, and oligonucleotides . Biotin-PEG-Alk (MW 600) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-148263
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Fluorescent Dye
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Cancer
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Biotin-PEG-Thiol (MW 2000) is an active compound. Biotin-PEG-Thiol (MW 2000) is pegylated by binding to streptavidin or antibiotin with high affinity and specificity. Biotin-PEG-Thiol (MW 2000) can modify biomolecules, proteins, peptides and other small molecule materials. Biotin-PEG-Thiol (MW 2000) is widely used in the research of agent release and nano new materials .
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- HY-P1468F
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Biotin-amyloid β-protein (1-28)
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Amyloid-β
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Others
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Biotin-β-amyloid (1-28) (Biotin-amyloid β-protein (1-28)) is abiotinylated β-Amyloid (1-28) (HY-P1468).
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- HY-140922
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PROTAC Linkers
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Cancer
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Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-150724A
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Toll-like Receptor (TLR)
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Inflammation/Immunology
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Biotin-labeled ODN 1018 (sodium), an oligodeoxynucleotide, is a TLR-9 agonist. Biotin-labeled ODN 1018 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
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- HY-140934
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PROTAC Linkers
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Cancer
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Biotin-PEG2-NH-Boc is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-151672
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ADC Linker
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Others
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Biotin-TEG-ATFBA is a click chemistry reagent containing a perfluorophenylazide group. Biotin-TEG-ATFBA forms a highly stable azene intermediate that undergoes insertion and addition reactions (non-intermolecular rearrangement) in moderate to good yields after photolysis.
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- HY-150743A
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Toll-like Receptor (TLR)
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Inflammation/Immunology
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Biotin-labeled ODN 2395 (sodium), a C class oligodeoxynucleotide, is a TLR9 agonist. Biotin-labeled ODN 2395 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
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- HY-150725A
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Toll-like Receptor (TLR)
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Inflammation/Immunology
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Biotin-labeled ODN 1585 (sodium) is a potent inducer of IFN and TNFα production. Biotin-labeled ODN 1585 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
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- HY-119343
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PROTAC Linkers
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Cancer
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Biotin-PFP ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130893
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PROTAC Linkers
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Cancer
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Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-126958
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- HY-18341F
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Thyroid Hormone Receptor
Endogenous Metabolite
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Endocrinology
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Biotin-(L-Thyroxine) is the biotinylated L-Thyroxine (HY-18341). L-Thyroxine is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from Biotin-(L-Thyroxine) (T4) .
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- HY-156377
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Drug-Linker Conjugates for ADC
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Cancer
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Biotin-PEG7-Maleimide is a biotinylation reagent that reacts with thiol groups (SH). Biotin-PEG7-Maleimide can be used as Drug-Linker Conjugates for ADCs .
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- HY-145383
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Fluorescent Dye
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Others
|
Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide is a clickable, acid-cleavable biotin-picolyl azide. Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide is an enrichment handle of cell surface glycoproteins for protein labeling .
|
-
- HY-150738A
-
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
Biotin-labeled ODN 2088 (sodium) is a potent TLR3, TLR7 and TLR9 inhibitor. Biotin-labeled ODN 2088 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
- HY-150726A
-
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
Biotin-labeled ODN 1668 (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. Biotin-labeled ODN 1668 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
- HY-146245A
-
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
Biotin-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. Biotin-labeled ODN 1826 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
- HY-B0511S2
-
Vitamin B7-d2; Vitamin H-d2; D-Biotin-d2
|
Endogenous Metabolite
|
Metabolic Disease
|
Biotin-d2 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
|
-
- HY-150741A
-
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
Biotin-labeled ODN 2216 (sodium) is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. Biotin-labeled ODN 2216 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
- HY-141729
-
|
Fluorescent Dye
|
Cancer
|
Biotin-NH-PSMA-617 is a biotin-tagged PSMA-617. PSMA-617 is a small molecule targeting the prostate-specific membrane antigen (PSMA), which is directly expressed by the tumor cells .
|
-
- HY-135179
-
(+)-Biotin-PEG3-OH
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
|
-
- HY-136769
-
|
Biochemical Assay Reagents
|
Others
|
Biotin-HPDP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-151741
-
|
ADC Linker
|
Others
|
Biotin-PEG4-MeTz is a click chemistry reagent containing a terminal methyltetrazine group that reacts with trans-cyclooctene. Biotin-PEG4-MeTz can be used for the preparation of biotinylated conjugates .
|
-
- HY-146219
-
|
PROTAC Linkers
|
Others
|
Biotin-nPEG-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-P3657A
-
|
Fluorescent Dye
|
Cancer
|
Biotin-KKKRKV acetate is the biotinylated KKKRKV acetate. KKKRKV is a nuclear localization signal (NLS) peptide derived from simian virus 40 .
|
-
- HY-151649
-
|
ADC Linker
|
Others
|
Biotin-PEG(4)-SS-Alkyne is a click chemistry reagent containing an alkyne group. Biotin-PEG(4)-SS-Alkyne can be used for the research of various biochemical .
|
-
- HY-151670
-
|
ADC Linker
|
Others
|
Biotin-PEG(4)-SS-Azide is a click chemistry reagent containing an azide group. Biotin-PEG(4)-SS-Azide can be used for the research of various biochemical .
|
-
- HY-126959
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
|
-
- HY-133176
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
|
-
- HY-W096127
-
|
ADC Linker
|
Cancer
|
Biotin-sar-oh is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-147169
-
|
Fluorescent Dye
|
Others
|
Biotin-X-NTA can be used for detecting histidine-tagged proteins immobilized on nitrocellulose membranes .
|
-
- HY-140910
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140911
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG6-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-156379
-
-
- HY-140494
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG36-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133377
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG24-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-129832
-
N-(3-Azidopropyl)Biotinamide
|
Biochemical Assay Reagents
|
Others
|
Biotin-azide (N-(3-Azidopropyl)biotinamide) is a form of biotin with a terminal azide group. Biotin-azide can be used to prepare various biotinylated conjugates via Click Chemistry . Biotin-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-B0511S
-
Vitamin B7 d2-1; Vitamin H d2-1; D-Biotin d2-1
|
Endogenous Metabolite
|
Metabolic Disease
|
Biotin-d2-1 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
|
-
- HY-P5830
-
|
Caspase
|
Others
|
Biotin-DEVD-CHO can be used for affinity labeling of Caspase-8 following in vitro caspase cleavage .
|
-
- HY-101885
-
Biotinamidocaproyl hydrazide; BACH; (+)-Biotinamidohexanoic Acid hydrazide; Biotin Aminocaproyl Hydrazide
|
Biochemical Assay Reagents
|
Others
|
Biotin LC hydrazide is a long chain protein modification reagent, which can transform periodate-oxidized glycoproteins.
|
-
- HY-138503
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-139107
-
|
ADC Linker
|
Cancer
|
Biotin-PEG4-SS-azide is a cleavable, biotin-labeled, ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biotin-PEG4-SS-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140940
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130290
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
|
-
- HY-130291
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
|
-
- HY-W010764
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG2-Mal is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
|
-
- HY-140942
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG6-Thalidomide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140938
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG3-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140897
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140901
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG23-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140904
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG12-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140903
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140905
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG24-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140933
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG12-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140939
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG11-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140936
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140909
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG11-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140892
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140906
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG36-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140890
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140891
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135941
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG9-NHS Ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135924
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135911
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140894
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133456
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG2-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133378
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133379
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG12-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134704
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138419
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG6-Silane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138426
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-allyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132112
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG2-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132114
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG3-pyridinrthiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132115
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140898
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-143855
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-143827
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG10-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W190970
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-147206D
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG-Alk (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG-Alk (MW 5000) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-156495
-
|
ADC Linker
|
Cancer
|
Biotin-PEG3-Me-Tet is an ADC Linker containing 3 PEG units. Biotin-PEG3-Me-Tet can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-135915
-
|
PROTAC Linkers
|
Cancer
|
Biotin-C5-NHS Ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135920
-
|
PROTAC Linkers
|
Cancer
|
Biotin-C10-NHS Ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140923
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-amide-Alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-amide-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140654
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG-amine (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140655
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG-amine (MW 3400) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140657
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG-triethoxysilane (MW 1000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140658
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG-triethoxysilane (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140659
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG-triethoxysilane (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W250928A
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG-azide (MW 600) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
|
-
- HY-W250928B
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG-azide (MW 1000) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
|
-
- HY-147205C
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG-OH (MW 5000) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
|
-
- HY-147205D
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG-OH (MW 10000) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
|
-
- HY-W250928E
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG-azide (MW 5000) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
|
-
- HY-147205A
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG-OH (MW 2000) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
|
-
- HY-147205
-
|
PROTAC Linkers
|
Others
|
Biotin-PEG-OH (MW 1000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-147205E
-
|
Fluorescent Dye
|
Others
|
Biotin-PEG-OH (MW 20000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W040254
-
|
Fluorescent Dye
|
Others
|
Biotin-LC-LC-NHS is a SMCC cross-linking reagent that can be used to mark antibody and other small molecules, such as Paclitaxel .
|
-
- HY-130560
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG3-propionic hydrazide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
|
-
- HY-136051
-
|
ADC Linker
|
Cancer
|
Biotin-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-138488
-
|
ADC Linker
|
Cancer
|
Biotin-PEG4-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-151667
-
DecarboxyBiotin-N3
|
Fluorescent Dye
|
Others
|
Biotin-C5-Azide (DecarboxyBiotin-N3) is a biotin reagent and can be used to prepare biotinylated conjugates . Biotin-C5-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-126957
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Biotin-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-133174
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Biotin-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-133175
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG7-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Biotin-PEG7-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-P3861
-
|
Neurokinin Receptor
|
Neurological Disease
|
Biotin-NeurokininA is a biotinylated NeurokininA (HY-P0197). Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues .
|
-
- HY-140935
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG5-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140937
-
|
PROTAC Linkers
|
Cancer
|
Biotin-amido-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140932A
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-hydrazide (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132116
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG3-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W190945
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG6-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140913
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG23-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG23-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140912
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG11-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG11-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-W096133
-
|
ADC Linker
|
Cancer
|
Biotin-PEG1-azide is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Biotin-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-D1546
-
|
Fluorescent Dye
|
Cancer
|
Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule .
|
-
- HY-B0315A
-
|
Endogenous Metabolite
|
Metabolic Disease
|
Biotin-Vitamin B12 is the biotinylated Vitamin B12. Vitamin B12 is a vitamin that plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood .
|
-
- HY-113828
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG2-C4-alkyne is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Biotin-PEG2-C4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-138508
-
|
ADC Linker
|
Cancer
|
Biotin-PEG2-methyl ethanethioate is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-145246
-
-
- HY-P1363F1
-
Biotin-amyloid β-peptide (1-42) (human) TFA
|
Amyloid-β
|
Neurological Disease
|
Biotin-β-Amyloid (1-42), human TFA (Biotin-Amyloid β-Peptide (1-42) (human) TFA) is the botin labeled β-Amyloid (1-42), human TFA (HY-P1363). β-Amyloid (1-42), human TFA is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .
|
-
- HY-W096135
-
|
ADC Linker
|
Cancer
|
Biotin-PEG1-NH2 is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140915
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-Picolyl azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-141091
-
|
Fluorescent Dye
|
Others
|
Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Biotin-PEG4-Dde-TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-P3623
-
|
Fluorescent Dye
|
Others
|
Biotin-Glucagon-Like Peptide 1 (7-36) amide, human is a biologically active peptide. Biotin-Glucagon-Like Peptide 1 (7-36) amide, human can be used for the research of various biochemical studies.
|
-
- HY-140941
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133457
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG2-C1-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096098
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140944
-
|
ADC Linker
|
Cancer
|
Biotin-PEG3-SS-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Biotin-PEG3-SS-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140131
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-PC-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-PC-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-117042
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG2-C6-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Biotin-PEG2-C6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-135916
-
|
PROTAC Linkers
|
Cancer
|
Biotin-C5-amino-C5-amino is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-157919
-
N-6-(Biotinylamino)hexanoyl-N'-[2-(N-maleimido)ethyl]piperazine, hydrochloride
|
Biochemical Assay Reagents
|
Others
|
Biotin-PEAC5-maleimide hydrochloride is a biochemical assay reagent, and can be used in biotin-PEAC5-maleimide (BPM)-labeling assay to assess modification of protein thiols by electrophiles .
|
-
- HY-156882
-
|
Others
|
Cancer
|
Biotin-PEG3-amide-C2-CO-Halofuginone, a kind halofuginone derivative, can be used in the cancer study .
|
-
- HY-133458
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG3-amido-SS-amido-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG3-amido-SS-amido-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140914
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-Amide-C6-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-135937
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG9-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096148
-
|
ADC Linker
|
Cancer
|
Biotin-C4-amide-C5-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-145247
-
-
- HY-140928
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133403A
-
|
PROTAC Linkers
|
Cancer
|
Biotin-C1-PEG3-C3-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-145667
-
Biotin-JQ1
|
Epigenetic Reader Domain
|
Cancer
|
Biotinylated-JQ1 (Biotin-JQ1) is a biotinylated derivative of JQ1 with high affinity for the bromodomain of BRD4. Biotinylated-JQ1 inhibits MM1.S multiple myeloma cells proliferation with the EC50 of 0.4 μM .
|
-
- HY-135912
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG2-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG2-CH2CH2N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140921
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-P3828
-
|
Fluorescent Dye
|
Neurological Disease
|
Biotin-myelin basic protein (94-102) is a peptide fragemt. Myelin basic protein is responsible for adhesion of the cytosolic surfaces of multilayered compact myelin, it plays an important role in the process of myelination of nerves in the nervous system. Myelin basic protein also acts as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin .
|
-
- HY-145248
-
-
- HY-156714
-
BPA-3',5'-pCp
|
Others
|
Cancer
|
Biotin-PEG4-alkane-3',5'-cytidine-bisphosphate (BPA-3',5'-pCp) is a 把iotin-PEG4-alkane modified nucleotide (GB2479833A; compound 6) .
|
-
- HY-131455A
-
|
Biochemical Assay Reagents
|
Others
|
Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 TFA is used for detection of modification site for N-myristoylated and GPI-anchored proteins in blood-stage P. falciparum . Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 (TFA) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-101884A
-
|
Others
|
Neurological Disease
|
Biotinylated-D-lysine TFA is a conjugate of L-biotin and D-lysine, where the carboxylate of L-biotin is coupled with the ϵ-amine of D-lysine via a secondary amide bond. Biotinylated-D-lysine TFA is an isomer of the neuroanatomical tracer Biocyte.
|
-
- HY-P1032F
-
|
Endogenous Metabolite
|
Endocrinology
|
Biotinyl-Angiotensin I (human, mouse, rat) is biotin-labeled Angiotensin I . Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE) .
|
-
- HY-125658
-
|
Others
|
Others
|
Biotinyl tyramide is a biotin derivative used for tyramide signal amplification (TSA), as a reagent to amplify both immunohistochemical signals and in situ hybridization protocols. Biotinyl tyramide can be used for the research of tyramide signal amplification .
|
-
- HY-P2504
-
|
Syk
|
Others
|
Syk Kinase Peptide Substrate, Biotin labeled is a biotin-labled Syk kinase peptide substrate.
|
-
- HY-P2491
-
|
Fluorescent Dye
|
Cardiovascular Disease
Endocrinology
|
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .
|
-
- HY-160297
-
|
Others
|
Others
|
GDP-FAzP4Biotin is a biotin junction structure .
|
-
- HY-136924
-
|
FAAH
|
Others
|
FP-biotin is a potent organophosphorus toxicant, well-suited for searching for new biomarkers of organophosphorus toxicants exposure. FP-Biotin quantifies FAAH, ABHD6, and MAG-lipase activity. FP-biotin is used for studies with plasma because biotinylated peptides are readily purified by binding to immobilized avidin beads .
|
-
- HY-147207A
-
|
Liposome
|
Others
|
Phospholipid-PEG-Biotin (MW 2000) is a Biotin labeled phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic “head” and two hydrophobic “tails”; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein .
|
-
- HY-144793
-
|
Others
|
Cancer
|
Deac-SS-Biotin is a potent antitumor agent. Deac-SS-Biotin uptakes into the cells through biotin-mediated internalization. Deac-SS-Biotin combined with DTT (Glutathione mimetic) can effectively inhibit microtubule assembly and displays greater antitumor activity .
|
-
- HY-D0183
-
|
Biochemical Assay Reagents
|
Others
|
ATP-polyamine-biotin, the first cell-permeable ATP analogue, is an efficient kinase cosubstrate. ATP-polyamine-biotin promotes biotin labeling of kinase substrates in live cells .
|
-
- HY-111496
-
|
Fluorescent Dye
|
Others
|
Sulfo-NHS-SS-biotin is a long-chain cleavable and cell-impermeant amine-reactive biotinylation reagent. Sulfo-NHS-SS-biotin can be used for the labeling and purifying of cell-surface protein .
|
-
- HY-147207C
-
|
Liposome
|
Others
|
Phospholipid-PEG-Biotin (MW 5000) is a phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic “head” and two hydrophobic “tails”; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein .
|
-
- HY-147102
-
|
LYTACs
|
Cancer
|
tri-GalNAc biotin is a small molecule lysosome targeting degrader. tri-GalNAc is a ligand of ASGPR (asialoglycoprotein receptor). tri-GalNAc biotin can facilitate the uptake of NeutrAvidin (NA) through ASGPR in liver cells. tri-GalNAc biotin delivers NeutrAvidin to lysosome for degradation. tri-GalNAc biotin can be used for research of LYsosome TArgeting Chimera (LYTAC) .
|
-
- HY-129214
-
-
- HY-147207
-
|
Liposome
|
Others
|
Phospholipid-PEG-Biotin (MW 1000) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
-
- HY-147207B
-
|
Liposome
|
Others
|
Phospholipid-PEG-Biotin (MW 3400) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
-
- HY-147207D
-
|
Liposome
|
Others
|
Phospholipid-PEG-Biotin (MW 10000) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
-
- HY-147207E
-
|
Liposome
|
Others
|
Phospholipid-PEG-Biotin (MW 20000) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
-
- HY-D1030
-
|
Fluorescent Dye
|
Inflammation/Immunology
|
Fluorescein Biotin is used as an alternative to radioactive biotin for detecting and quantitating biotin-binding sites by either fluorescence or absorbance; the the fluorescence or absorbance of Fluorescein Biotin is quenched, upon binding to avidin or streptavidin.
|
-
- HY-139009
-
|
HSP
|
Cancer
|
HA15-Biotin is a chemical probe that consists of HA15 and biotin attached on the amide part of HA15. HA15-Biotin exhibits similar levels of activity to HA15. HA15-Biotin can be used for proteomic analysis .
|
-
- HY-P2510
-
|
Thyroid Hormone Receptor
|
Metabolic Disease
|
Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor, can be used for analyzing the interaction between parathyroid hormone and parathyroid hormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns .
|
-
- HY-145057
-
|
Others
|
Cancer
|
PP-biotin is an irreversible, biotin-labeled probe .
|
-
- HY-W048449
-
|
Others
|
Metabolic Disease
|
L-Biotin, also known as biotin, is a water-soluble vitamin that is an essential cofactor in the carboxylation of several enzymes. L-Biotin is involved in fatty acid synthesis and amino acid metabolism .
|
-
- HY-140946
-
|
Fluorescent Dye
|
Others
|
TAMRA-PEG3-biotin is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-biotin is tagged with biotin.
|
-
- HY-W441000
-
|
Liposome
|
Others
|
DSPE-Biotin is a lipid. DSPE-Biotin can be used for the research of various biochemical .
|
-
- HY-130809
-
|
Biochemical Assay Reagents
|
Cancer
|
DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction . DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-157807
-
-
- HY-111377
-
|
Fluorescent Dye
|
Others
|
Amine-PEG3-Biotin is a signal amplification label containing a biotin group and a terminal primary amine group .
|
-
- HY-163039
-
|
Others
|
Inflammation/Immunology
|
DOTA-biotin is a DOTA-based small molecule hapten. DOTA-biotin has low tissue and whole-body retention in mice 4 h postinjection .
|
-
- HY-P1405
-
-
- HY-157173
-
|
Others
|
Inflammation/Immunology
|
Mannosamine–biotin adduct is a hapten. Mannosamine–biotin adduct conjugated to hsIgG significantly reduces antibody immune responses against hsIgG .
|
-
- HY-130888
-
(+)-Biotin 4-nitrophenyl ester
|
PROTAC Linkers
|
Cancer
|
(+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141183
-
|
PROTAC Linkers
|
Cancer
|
TCO-PEG4-biotin is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-140448
-
|
PROTAC Linkers
|
Cancer
|
Diketone-PEG4-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141094
-
|
PROTAC Linkers
|
Cancer
|
Pyrene-PEG5-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140449
-
|
PROTAC Linkers
|
Cancer
|
Diketone-PEG12-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138490
-
|
PROTAC Linkers
|
Cancer
|
Iodoacetyl-PEG8-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138491
-
|
PROTAC Linkers
|
Cancer
|
Iodoacetyl-PEG4-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-136050
-
|
ADC Linker
|
Cancer
|
TCO-PEG3-Biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG3-Biotin is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-136053
-
|
ADC Linker
|
Cancer
|
Tetrazine-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130924
-
|
ADC Linker
|
Cancer
|
BCN-PEG3-Biotin is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG3-Biotin is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-100342
-
|
Btk
|
Cancer
|
Ibrutinib-biotin is a probe that consists of Ibrutinib linked to biotin via a long chain linker, extracted from patent WO2014059368A1 Compound 1-5, has an IC50 of 0.755-1.02 nM for BTK.
|
-
- HY-D1938
-
|
Fluorescent Dye
|
Others
|
ATTO 465 Biotin is a biotin derivative of ATTO 465 with maximum excitation/emission wavelengths: 453/506 nm.
|
-
- HY-D1942
-
|
Fluorescent Dye
|
Others
|
ATTO 590 Biotin is a biotin derivative of ATTO 590 with maximum excitation/emission wavelengths: 594/622 nm.
|
-
- HY-D1951
-
|
Fluorescent Dye
|
Others
|
ATTO 594 Biotin is a biotin derivative of ATTO 594 with maximum excitation/emission wavelengths: 603/626 nm.
|
-
- HY-D1964
-
|
Fluorescent Dye
|
Others
|
ATTO 633 Biotin is a biotin derivative of ATTO 633 with maximum excitation/emission wavelengths: 630/651 nm.
|
-
- HY-D1965
-
|
Fluorescent Dye
|
Others
|
ATTO 700 Biotin is a biotin derivative of ATTO 700 with maximum excitation/emission wavelengths: 700/716 nm.
|
-
- HY-D1978
-
|
Fluorescent Dye
|
Others
|
ATTO 610 Biotin is a biotin derivative of ATTO 610 with maximum excitation/emission wavelengths: 616/633 nm.
|
-
- HY-D1988
-
|
Fluorescent Dye
|
Others
|
ATTO 620 Biotin is a biotin derivative of ATTO 620 with maximum excitation/emission wavelengths: 620/642 nm.
|
-
- HY-D1989
-
|
Fluorescent Dye
|
Others
|
ATTO 725 Biotin is a biotin derivative of ATTO 725 with maximum excitation/emission wavelengths: 728/751 nm.
|
-
- HY-D1996
-
|
Fluorescent Dye
|
Others
|
ATTO 647 Biotin is a biotin derivative of ATTO 647 with maximum excitation/emission wavelengths: 630/651 nm.
|
-
- HY-D2003
-
|
Fluorescent Dye
|
Others
|
ATTO 565 biotin is a biotin derivative of ATTO 565 with maximum excitation/emission wavelengths: 564/590 nm.
|
-
- HY-D2007
-
|
Fluorescent Dye
|
Others
|
ATTO 488 biotin is a biotin derivative of ATTO 488 with maximum excitation/emission wavelengths: 500/520 nm.
|
-
- HY-D2025
-
|
Fluorescent Dye
|
Others
|
ATTO 550 biotin is a biotin derivative of ATTO 550 with maximum excitation/emission wavelengths: 554/576 nm.
|
-
- HY-D2076
-
|
Fluorescent Dye
|
Others
|
ATTO 740 biotin is a biotin derivative of ATTO 740 with maximum excitation/emission wavelengths: 743/763 nm.
|
-
- HY-D2031
-
|
Fluorescent Dye
|
Others
|
ATTO 514 biotin is a biotin derivative of ATTO 514 with maximum excitation/emission wavelengths: 511/531 nm.
|
-
- HY-D2049
-
|
Fluorescent Dye
|
Others
|
ATTO 532 biotin is a biotin derivative of ATTO 532 with maximum excitation/emission wavelengths: 532/552 nm.
|
-
- HY-D1911
-
|
Fluorescent Dye
|
Others
|
ATTO 665 Biotin is a biotin derivative of ATTO 665 with maximum excitation/emission wavelengths: 663/680 nm.
|
-
- HY-D2065
-
|
Fluorescent Dye
|
Others
|
ATTO 680 biotin is a biotin derivative of ATTO 680 with maximum excitation/emission wavelengths: 681/698 nm.
|
-
- HY-135939
-
|
PROTAC Linkers
|
Cancer
|
DBCO-NHCO-PEG2-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG2-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-135958
-
|
PROTAC Linkers
|
Cancer
|
DBCO-NHCO-PEG6-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG6-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133376
-
|
PROTAC Linkers
|
Cancer
|
DBCO-NHCO-PEG12-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG12-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D1870
-
|
Fluorescent Dye
|
Others
|
Sulfo-Cy3-PEG3-biotin potassium is a biotin-modified derivative of Cy3 (Cyanine3) (HY-D0822) dye containing a TCO group. The TCO group of Sulfo-Cy3-PEG3-biotin potassium reacts with the tetrazine functional group in highly specific click chemistry to form a covalent bond. Thus, Sulfo-Cy3-PEG3-biotin potassium can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples. And because it is labeled with biotin, it is often used in affinity chromatography experiments, such as immunoprecipitation.
|
-
- HY-123916
-
|
PROTAC Linkers
|
Cancer
|
DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140136
-
|
ADC Linker
|
Cancer
|
PC DBCO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC DBCO-PEG3-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-135979
-
|
ADC Linker
|
Cancer
|
DBCO-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-SS-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-136095
-
|
ADC Linker
|
Cancer
|
Tetrazine-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D1923
-
|
Fluorescent Dye
|
Others
|
ATTO 390 biotin is a biotin derivative of ATTO 390, used for streptavidin reaction, maximum excitation/emission wavelength: 390/476 nm.
|
-
- HY-D1927
-
|
Fluorescent Dye
|
Others
|
ATTO 425 Biotin is a biotin derivative of ATTO 425, used for streptavidin reaction, the maximum excitation emission wavelength: 439/489 nm.
|
-
- HY-D2226
-
-
- HY-136035
-
|
ADC Linker
|
Cancer
|
Methyltetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-SS-PEG4-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136036
-
|
ADC Linker
|
Cancer
|
Tetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-PEG4-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136078
-
|
ADC Linker
|
Cancer
|
Tetrazine-diazo-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-diazo-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-163036
-
-
- HY-140128
-
|
PROTAC Linkers
|
Cancer
|
DBCO-S-S-PEG3-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-S-S-PEG3-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130887
-
|
PROTAC Linkers
|
Cancer
|
(+)-Biotin-SLC is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-P2609F
-
|
PACAP Receptor
|
Others
|
PACAP (1-38), amide, Biotin-labeled is a biological active peptide. (Biotin-labeled HY-P0221)
|
-
- HY-W010721
-
-
- HY-136031
-
|
ADC Linker
|
Cancer
|
Tetrazine-SS-Biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130889
-
(+)-Biotin-PEG10-alcohol
|
PROTAC Linkers
|
Cancer
|
(+)-Biotin-PEG10-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-137360
-
|
Others
|
Others
|
Phosphine-biotin is a labeling reagent that selectively reacts with azido groups on modified proteins through the Staudinger ligation reaction .
|
-
- HY-160299
-
|
Others
|
Others
|
GDP-Fuc-Biotin is a biotinylated GDP-Fucose that can be used to conjugate antibodies .
|
-
- HY-130477
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-Lys (biotin-PEG4)-OH is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-142080
-
|
Bacterial
|
Infection
|
Pimeloyl-CoA is a biotin precursor of Escherichia coli. Pimeloyl-CoA can be used for the research of the pathway of de novo biotin biosynthesis in Escherichia coli .
|
-
- HY-140129
-
|
ADC Linker
|
Cancer
|
NHS-SS-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-B0511S1
-
rel-Vitamin B7-d4; rel-Vitamin H-d4; rel-D-Biotin-d4
|
Endogenous Metabolite
|
Metabolic Disease
|
rel-Biotin-d4 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
|
-
- HY-136964
-
|
Others
|
Others
|
Sulfo-NHS-Biotin (sodium) stongly label single SDS-2ME soluble cuticular protein .
|
-
- HY-130810
-
|
ADC Linker
|
Cancer
|
DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-Link-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140927
-
UV Cleavable Biotin-PEG2-alkyne
|
PROTAC Linkers
|
Cancer
|
Azido-C3-UV-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-C3-UV-biotin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-145249
-
|
PROTAC Linkers
|
Inflammation/Immunology
|
ATP-PEG8-Biotin is a PEG-based linker that incorporates ATP. ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation .
|
-
- HY-W127773
-
|
Biochemical Assay Reagents
|
Others
|
KNI-1293 Biotin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-D0799
-
|
Fluorescent Dye
|
Others
|
Sulfo-NHS-LC-Biotin sodium is an amine-reactive biotinylation reagent that can be used for antibody labeling .
|
-
- HY-140929
-
|
PROTAC Linkers
|
Cancer
|
Bis-Biotin-PEG23 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138065
-
|
Apoptosis
|
Others
|
Iodoacetyl-LC-biotin is a biotinylated electrophile probe that can be used to investigate the scope and characteristics of protein covalent binding to subcellular proteomes .
|
-
- HY-D1403
-
|
Fluorescent Dye
|
Cancer
|
L-Biotin-NH-5MP is a biotin-conjugated 5-Methylene pyrrolone (5MP). 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation .
|
-
- HY-140127
-
|
ADC Linker
|
Cancer
|
Azide-C2-SS-C2-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azide-C2-SS-C2-biotin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130890
-
|
PROTAC Linkers
|
Cancer
|
(+)-Biotin-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130891
-
|
PROTAC Linkers
|
Cancer
|
(+)-Biotin-PEG6-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130892
-
|
PROTAC Linkers
|
Cancer
|
(+)-Biotin-PEG2-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140947
-
|
Fluorescent Dye
|
Others
|
TAMRA-Azide-PEG-biotin is a dye derivative of TAMRA (HY-135640). TAMRA-Azide-PEG-biotin contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140532
-
|
PROTAC Linkers
|
Cancer
|
N-(Amino-PEG4)-N-Biotin-PEG4-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D1695
-
-
- HY-140924
-
|
PROTAC Linkers
|
Cancer
|
Dde Biotin-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140931
-
|
PROTAC Linkers
|
Cancer
|
Dde Biotin-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140925
-
|
PROTAC Linkers
|
Cancer
|
Diazo Biotin-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Diazo Biotin-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140137
-
|
PROTAC Linkers
|
Cancer
|
WSPC Biotin-PEG3-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . WSPC Biotin-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130929
-
|
ADC Linker
|
Cancer
|
β-Estradiol-6-CMO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140877
-
|
Fluorescent Dye
|
Others
|
Dde Biotin-PEG4-TAMRA-PEG4 Alkyne is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Dde Biotin-PEG4-TAMRA-PEG4 Alkyne contains Alkyne groups that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D1406
-
|
Fluorescent Dye
|
Others
|
L-Biotin-NH-5MP-Br is a biotin-conjugated 5-Methylene pyrrolone (5MP). 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation .
|
-
- HY-140930
-
|
ADC Linker
|
Cancer
|
Diazo Biotin-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Diazo Biotin-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140130
-
|
ADC Linker
|
Cancer
|
PC Biotin-PEG3-alkyne is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC Biotin-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-148865
-
|
Others
|
Others
|
Puromycin-bis(PEG2-amide)-Biotin is used for single-cell translatome sequencing .
|
-
- HY-140134
-
|
ADC Linker
|
Cancer
|
PC Biotin-PEG3-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140736
-
-
- HY-140736A
-
|
PROTAC Linkers
|
Others
|
DSPE-PEG-Biotin, MW 1000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140736B
-
-
- HY-140528
-
|
PROTAC Linkers
|
Cancer
|
N-Biotin-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140135
-
|
PROTAC Linkers
|
Cancer
|
PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140945
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-Lys (biotin-PEG12)-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140918
-
|
PROTAC Linkers
|
Cancer
|
Diazo Biotin-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Diazo Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140916
-
|
PROTAC Linkers
|
Cancer
|
Dde Biotin-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140132
-
|
ADC Linker
|
Cancer
|
PC Biotin-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-132276
-
|
Others
|
Others
|
PtdIns-(3,4,5)-P3-biotin sodium is a Biotin-labeled PtdIns-(3,4,5)-P3 (PI(3,4,5)P3). PI(3,4,5)P3 is a substrate of nuclear phosphatidylinositol 5-phosphatase (PIP5Pase). PI(3,4,5)P3 binds to the N-terminus of RAP1 (repressor activator protein 1) and controls its DNA binding activity .
|
-
- HY-140949
-
|
PROTAC Linkers
|
Cancer
|
N-(Biotin)-N-bis(PEG1-alcohol) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W440886
-
|
Liposome
|
|
DSPE-PEG-Biotin, MW 3400 is a phospholipid PEG for biotinylation. The amphiphilic property of the DSPE-PEG is useful for precision drug delivery and cancer therapy.
|
-
- HY-140920
-
|
PROTAC Linkers
|
Cancer
|
UV Cleavable Biotin-PEG2-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . UV Cleavable Biotin-PEG2-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140917
-
|
PROTAC Linkers
|
Cancer
|
Dde Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-Picolyl azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-P3616
-
|
GCGR
|
Metabolic Disease
|
Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide is a biotin labeled glucagon-like peptide-1-(7-36). Glucagon-like peptide-1-(7-36) is a gastrointestinal peptide with antidiabetogenic activity, and can increase the release of insulin .
|
-
- HY-W096159
-
|
Endogenous Metabolite
|
Metabolic Disease
|
D-Biotinol is the nutrition of Lactobacillus arabinosus, L. casei, or Saccharomyces cerevisiae. D-Biotinol replaces the D-biotin (HY-B0511) in saving egg white induced biotin deficiency in rats. D-Biotinol is orally active and displays to be converted to biotin by rats .
|
-
- HY-157916
-
Aldehyde reactive probe
|
Fluorescent Dye
|
Others
|
ARP (Aldehyde reactive probe) is an aldehyde reactive probe for detecting abasic site (common DNA lesions and intermediates in mutagenesis and carcinogenesis) in DNA, which specificially tags AP site with biotin residues. ARP is highly sensitive with a femtomolar-level basic site detection capabilities (less than one site per 10 4 nucleotides) .
|
-
- HY-113409
-
|
Endogenous Metabolite
|
Metabolic Disease
|
3-Hydroxyisovaleric acid is a normal endogenous metabolite excreted in the urine. The urinary excretion of 3-hydroxyisovaleric acid is early and sensitive indicator of biotin deficiency .
|
-
- HY-140531
-
|
PROTAC Linkers
|
Cancer
|
N-(Biotin-PEG4)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140902
-
|
PROTAC Linkers
|
Cancer
|
rel-Biotin-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140582
-
|
PROTAC Linkers
|
Cancer
|
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-115448
-
|
Bacterial
|
Infection
|
Bio-AMS is a potent bacterial biotin protein ligase inhibitor. Bio-AMS possesses selective activity against Mycobacterium tuberculosis (Mtb) and arrests fatty acid and lipid biosynthesis .
|
-
- HY-140133
-
|
ADC Linker
|
Cancer
|
PC-Biotin-PEG4-PEG3-azide is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC-Biotin-PEG4-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-115448A
-
|
Bacterial
|
Infection
|
Bio-AMS (TFA) is a potent bacterial biotin protein ligase inhibitor. Bio-AMS (TFA) possesses selective activity against Mycobacterium tuberculosis (Mtb) and arrests fatty acid and lipid biosynthesis .
|
-
- HY-125392
-
|
PROTAC Linkers
|
Cancer
|
2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W110146
-
-
- HY-141288
-
|
PROTAC Linkers
|
Cancer
|
N-(Biotin-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-141070
-
|
PROTAC Linkers
|
Cancer
|
N-(m-PEG4)-N'-(biotin-PEG3)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140581
-
|
PROTAC Linkers
|
Cancer
|
N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-155681
-
|
PD-1/PD-L1
Monoamine Oxidase
|
Cancer
|
SWS1 is a d-(+)-biotin-conjugated PD-L1 inhibitor (IC50: 1.8 nM) with anticancer activity. SWS1 can increase the number of tumor-infiltrating lymphocytes and exhibit anti-tumor efficacy in the B16-F10 mouse model (TGI=66.1%) .
|
-
- HY-P2535
-
|
GLP Receptor
|
Metabolic Disease
|
Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human is an C-terminal-labelled biotinylated GLP-1 (7-36) amide.
|
-
- HY-128699
-
DethioBiotin
|
Endogenous Metabolite
|
Others
|
D-Desthiobiotin is a biotin derivative used in affinity chromatography and protein chromatography. D-Desthiobiotin also can be used for protein and cell labeling, detection and isolation .
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-
- HY-141069
-
|
PROTAC Linkers
|
Cancer
|
N-(m-PEG4)-N'-(Biotin-PEG2-amido-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-D1804
-
|
Fluorescent Dye
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Others
|
Vari Fluor 680-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=680 nm/701 nm.
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-
- HY-D1805
-
|
Fluorescent Dye
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Others
|
Vari Fluor 647-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=650 nm/665 nm.
|
-
- HY-D1806
-
|
Fluorescent Dye
|
Others
|
Vari Fluor 594-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=590 nm/617 nm.
|
-
- HY-D1807
-
|
Fluorescent Dye
|
Others
|
Vari Fluor 555-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=555 nm/565 nm.
|
-
- HY-D1808
-
|
Fluorescent Dye
|
Others
|
Vari Fluor 488-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=490 nm/515 nm.
|
-
- HY-D1809
-
|
Fluorescent Dye
|
Others
|
Vari Fluor 405-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=405 nm/431 nm.
|
-
- HY-N11200
-
|
Endogenous Metabolite
|
Metabolic Disease
|
3-Hydroxyisovalerylcarnitine is a carnitine derivative. 3-Hydroxyisovaleryl carnitine in plasma may serve as a novel biomarker of biotin deficiency in humans, with its concentration increasing with biotin deficiency. Biotin deficiency reduces the activity of biotin-dependent 3-methylcrotonyl-CoA carboxylase, hinders the conversion of 3-methylcrotonyl-CoA into 3-methylglutaconyl-CoA, and impairs the leucine catabolism pathway; resulting in plasma 3-Hydroxyisovalerylcarnitine concentrations rise .
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-
- HY-135682
-
-
- HY-153846
-
|
Others
|
Others
|
RNA Aptamer Mango Ⅰ (sodium) consists of 39 nucleotides and has an exceptionally high affinity to TO1-biotin (a thiazole orange derivative fluorophore). RNA Aptamer Mango Ⅰ (sodium) can be used to visualize RNA expression or localization in live cells.
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-
- HY-153850
-
|
Others
|
Others
|
RNA Aptamer Peach Ⅰ (sodium) has an exceptionally high affinity to TO3-Biotin (TO3-B, red channel, ex: 637 nm, em: 658 nm), and can be used to visualize RNA expression or localization in live cells.
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-
- HY-153851
-
|
Others
|
Others
|
RNA Aptamer Peach Ⅱ (sodium) has an exceptionally high affinity to TO3-Biotin (TO3-B, red channel, ex: 637 nm, em: 658 nm), and can be used to visualize RNA expression or localization in live cells.
|
-
- HY-D1919
-
|
Fluorescent Dye
|
Others
|
ATTO 390 amine is a biotin derivative of ATTO 390 with maximum excitation/emission wavelengths: 390/476 nm.
|
-
- HY-101884
-
(+)-Biocytin
|
Endogenous Metabolite
|
Neurological Disease
|
Biocytin is a conjugate of D-biotin and L-lysine, where the carboxylate of D-biotin is coupled with the ϵ-amine of L-lysine via a secondary amide bond. Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is used as a versatile marker in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays .
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-
- HY-153847
-
|
Others
|
Others
|
RNA Aptamer Mango Ⅱ (sodium) has an exceptionally high affinity to TO1-biotin (a thiazole orange derivative fluorophore), and can be used to visualize RNA expression or localization in live cells. Compared to the original Mango I aptamer, RNA Aptamer Mango Ⅱ (sodium) has markedly improved fluorescent properties, binding affinities, and salt dependencies.
|
-
- HY-153848
-
|
Others
|
Others
|
RNA Aptamer Mango Ⅳ (sodium) has an exceptionally high affinity to TO1-biotin (a thiazole orange derivative fluorophore), and can be used to visualize RNA expression or localization in live cells. Compared to the original Mango I aptamer, RNA Aptamer Mango Ⅳ has markedly improved fluorescent properties, binding affinities, and salt dependencies.
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-
- HY-153849
-
|
Others
|
Others
|
RNA Aptamer Mango Ⅲ (sodium) has an exceptionally high affinity to TO1-biotin (a thiazole orange derivative fluorophore), and can be used to visualize RNA expression or localization in live cells. Compared to the original Mango I aptamer, RNA Aptamer Mango Ⅲ has markedly improved fluorescent properties, binding affinities, and salt dependencies.
|
-
- HY-147168
-
|
Others
|
Metabolic Disease
|
Biocytin hydrazide is a selective label for sialic acids, galactose, and other sugars in glycoconjugates using avidin-biotin technology .
|
-
- HY-W038001
-
|
Others
|
Cancer
|
DOTA-benzene is a DOTA-based small molecule hapten. DOTA-biotin has been used extensively as a hapten for PRIT .
|
-
- HY-113930
-
|
Others
|
Others
|
3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid is a SS-biotin that can be utilized in cellular proximity biotinylation assays to label interactors .
|
-
- HY-116872
-
|
Bacterial
|
Infection
|
MAC13772 is a potent inhibitor of the enzyme BioA (IC50=250 nM), the antepenultimate step in biotin biosynthesis. MAC13772 is a novel antibacterial compound .
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-
- HY-135717
-
|
Others
|
Cancer
|
Norbiotinamine is an alternative to biotin. Norbiotinamine can be coupled with a carboxylic group of amino acids to give inverse peptides, having the amide linkage oriented in the opposite direction .
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-
- HY-135717A
-
|
Others
|
Cancer
|
Norbiotinamine hydrochloride is an alternative to biotin. Norbiotinamine can be coupled with a carboxylic group of amino acids to give inverse peptides, having the amide linkage oriented in the opposite direction .
|
-
- HY-136849
-
|
Others
|
Others
|
TL13-68 is a biotin-tagged version of SM1-71, and it can be used to research the mechanism of SM1-71 .
|
-
- HY-D2170
-
|
Fluorescent Dye
|
Others
|
AF488 streptavidin is a fluorescence labeled streptavidin. AF488 streptavidin comprises a biotin-binding protein (streptavidin) covalently attached to a fluorescent label (AF488). AF488 is a bright, photostable green fluorophore .
|
-
- HY-124781
-
|
Bacterial
Antibiotic
|
Infection
|
ML406 is a small molecule probe that shows anti-tubercular activity via M.tuberculosis BioA (DAPA synthase) enzyme inhibition with an IC50 of 30 nM. M.tuberculosis BioA is an enzyme involved in biotin biosynthesis in M.tuberculosis .
|
-
- HY-P2989
-
|
Endogenous Metabolite
|
Metabolic Disease
|
Pyruvate carboxylase is a biotin-containing enzyme that catalyzes the HCO3 − and MgATP dependent carboxylation of pyruvate to form oxaloacetate. Pyruvate carboxylase plays an essential role in controlling whole-body energetics through regulation of gluconeogenesis in the liver, synthesis of fatty acids in adipocytes, and insulin secretion in pancreatic β cells .
|
-
- HY-153797
-
-
- HY-125965
-
|
Bacterial
|
Infection
|
BioA-IN-13 is a potent, cell permeable and whole-cell active inhibitor of Mycobacterium tuberculosis BioA enzyme .
|
-
- HY-100627
-
|
MEK
|
Cancer
|
APS-2-79 is a KSR-dependent MEK antagonist. APS-2-79 inhibits ATP biotin binding to KSR2 within the KSR2-MEK1 complexe with an IC50 of 120 nM. APS-2-79 makes the stabilization of the KSR inactive state antagonizes oncogenic Ras-MAPK signaling .
|
-
- HY-100627A
-
|
|
|
APS-2-79 hydrochloride is a KSR-dependent MEK antagonist. APS-2-79 inhibits ATP biotin binding to KSR2 within the KSR2-MEK1 complexe with an IC50 of 120 nM. APS-2-79 makes the stabilization of the KSR inactive state antagonizes oncogenic Ras-MAPK signaling .
|
-
- HY-148979
-
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphorylethanolamine
|
Fluorescent Dye
|
Cancer
|
SAPE (1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphorylethanolamine) is an R-Phycoerythrin (HY-D0988) labeled Streptavidin (HY-P3152) fluorescent probe. SAPE can be used for tumor detection when combined with biotin. SAPE has high sensitivity and a wide detection range .
|
-
- HY-118700
-
GuanidinoBiotin
|
NO Synthase
|
Neurological Disease
|
2-Iminobiotin (Guanidinobiotin) is a biotin (vitamin H or B7) analog. 2-Iminobiotin is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5μM for murine iNOS and rat n-cNOS, respectively . 2-Iminobiotin superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage .
|
-
- HY-D1687
-
|
Fluorescent Dye
|
Others
|
Flubi-2 is a fluorescein-biotin based pH-ratio dye (Ex=480 nm, Em= 520-560 nm) with a pK value of 6.7. Flubi-2 is a hydrolysis product of Flubida-2 (non-fluorescent, membrane permeable). Flubi-2 can be used for pH determination of organelles of the secretory pathway (such as golgi apparatus and endoplasmic reticulum) in living cells .
|
-
- HY-112295
-
|
Biochemical Assay Reagents
|
Infection
|
AzKTB is a capture reagent which bears a short trypsin-cleavable peptide sequence between the azide module and the TAMRA/PEG-biotin labels. AzKTB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-100338
-
|
|
|
CNX-500 is a probe consisting of a covalent Btk inhibitor (CC-292) chemically linked to biotin. CNX-500 retains inhibitory activity against Btk (IC50 of 0.5 nM) and the ability to form a covalent bond with Btk. CNX-500 has low inhibitory effects on kinase epidermal growth factor receptor, and upstream Src-family kinases including Syk and Lyn .
|
-
- HY-118700A
-
GuanidinoBiotin hydrobromide
|
NO Synthase
|
Neurological Disease
|
2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5 μM for murine iNOS and rat n-cNOS, respectively . 2-Iminobiotin hydrobromide superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage .
|
-
- HY-144012A
-
DPPE-PEG350; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Liposome
|
Others
|
16:0 PEG350 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144012B
-
DPPE-PEG550; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Biochemical Assay Reagents
Liposome
|
Others
|
16:0 PEG550 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144012C
-
DPPE-PEG750; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium
|
Biochemical Assay Reagents
Liposome
|
Others
|
16:0 PEG750 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013A
-
DSPE-mPEG350 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Liposome
|
Others
|
18:0 mPEG350 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013B
-
DSPE-mPEG550 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Biochemical Assay Reagents
Liposome
|
Others
|
18:0 mPEG550 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013C
-
DSPE-mPEG750 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium
|
Biochemical Assay Reagents
Liposome
|
Others
|
18:0 mPEG750 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144012D
-
DPPE-PEG1000; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Liposome
|
Others
|
16:0 PEG1000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144012E
-
DPPE-PEG3000; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Liposome
|
Others
|
16:0 PEG3000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144012H
-
DPPE-PEG5000; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Liposome
|
Others
|
16:0 PEG5000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013D
-
DSPE-mPEG1000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Liposome
|
Others
|
18:0 mPEG1000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013E
-
DSPE-mPEG3000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Liposome
|
Others
|
18:0 mPEG3000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013H
-
DSPE-mPEG5000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Liposome
|
Others
|
18:0 mPEG5000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155924
-
DMPE-PEG350; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Liposome
|
Others
|
14:0 PEG350 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155925
-
DMPE-PEG550; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Liposome
|
Others
|
14:0 PEG550 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155926
-
DMPE-PEG750; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium
|
Liposome
|
Others
|
14:0 PEG750 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155927
-
DMPE-PEG1000; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Liposome
|
Others
|
14:0 PEG1000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155928
-
DMPE-PEG3000; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Liposome
|
Others
|
14:0 PEG3000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155929
-
DMPE-PEG5000; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Liposome
|
Others
|
14:0 PEG5000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155930
-
DOPE-PEG350; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Liposome
|
Others
|
18:1 PEG350 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155931
-
DOPE-PEG550; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Liposome
|
Others
|
18:1 PEG550 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155932
-
DOPE-PEG1000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Liposome
|
Others
|
18:1 PEG1000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155933
-
DOPE-PEG3000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Liposome
|
Others
|
18:1 PEG3000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155934
-
DOPE-PEG5000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Liposome
|
Others
|
18:1 PEG5000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
Cat. No. |
Product Name |
Type |
-
- HY-D0802
-
Biotin NHS
Maximum Cited Publications
7 Publications Verification
Biotin-NHS; Biotin N-hydroxysuccinimide ester; NHS-Biotin
|
Fluorescent Dyes/Probes
|
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.
|
-
- HY-D1669
-
|
Fluorescent Dyes/Probes
|
Biotin-11-UTP is a Biotin-labeled uridine triphosphate (UTP), containing 11 atoms in the linker between biotin and UTP. Biotin-11-UTP can biotinylate transcribed RNA in vitro and has been widely used as labeling RNA probe . Biotin-11-UTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D1022
-
Biotin-16-deoxyuridine-5'-triphosphate
|
Fluorescent Dyes/Probes
|
Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
|
-
- HY-135641
-
|
Fluorescent Dyes/Probes
|
Biotin-probe 1 is a non-radiolabeled probe. Biotin-labeled probes can be applied to in situ hybridization .
|
-
- HY-D1022A
-
Biotin-16-deoxyuridine-5'-triphosphate trisodium
|
Fluorescent Dyes/Probes
|
Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .
|
-
- HY-D1686
-
|
Fluorescent Dyes/Probes
|
Biotin-16-UTP is an active substrate for RNA polymerase. Biotin-16-UTP can replace UTP in the in vitro transcription reaction for RNA labeling .
|
-
- HY-D1029
-
-
- HY-D1668
-
|
Fluorescent Dyes/Probes
|
Biotin-11-dCTP is a fluorescent dye for DNA labeling . Biotin-11-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D1029A
-
-
- HY-D1839
-
Biotin Tyramide
|
Dyes
|
Biotin TSA(200×) (Biotin Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
|
-
- HY-18341F
-
|
Dyes
|
Biotin-(L-Thyroxine) is the biotinylated L-Thyroxine (HY-18341). L-Thyroxine is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from Biotin-(L-Thyroxine) (T4) .
|
-
- HY-145383
-
|
Protein Labeling
|
Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide is a clickable, acid-cleavable biotin-picolyl azide. Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide is an enrichment handle of cell surface glycoproteins for protein labeling .
|
-
- HY-18341F1
-
|
Dyes
|
Biotin-hexanamide-(L-Thyroxine) is biotinylated L-Thyroxine (HY-18341). L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism .
|
-
- HY-D1546
-
|
Fluorescent Dyes/Probes
|
Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule .
|
-
- HY-B0315A
-
|
Fluorescent Dyes/Probes
|
Biotin-Vitamin B12 is the biotinylated Vitamin B12. Vitamin B12 is a vitamin that plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood .
|
-
- HY-111496
-
|
Dyes
|
Sulfo-NHS-SS-biotin is a long-chain cleavable and cell-impermeant amine-reactive biotinylation reagent. Sulfo-NHS-SS-biotin can be used for the labeling and purifying of cell-surface protein .
|
-
- HY-D1030
-
|
Fluorescent Dyes/Probes
|
Fluorescein Biotin is used as an alternative to radioactive biotin for detecting and quantitating biotin-binding sites by either fluorescence or absorbance; the the fluorescence or absorbance of Fluorescein Biotin is quenched, upon binding to avidin or streptavidin.
|
-
- HY-111377
-
|
Chromogenic Assays
|
Amine-PEG3-Biotin is a signal amplification label containing a biotin group and a terminal primary amine group .
|
-
- HY-D1938
-
|
Fluorescent Dyes/Probes
|
ATTO 465 Biotin is a biotin derivative of ATTO 465 with maximum excitation/emission wavelengths: 453/506 nm.
|
-
- HY-D1942
-
|
Fluorescent Dyes/Probes
|
ATTO 590 Biotin is a biotin derivative of ATTO 590 with maximum excitation/emission wavelengths: 594/622 nm.
|
-
- HY-D1951
-
|
Fluorescent Dyes/Probes
|
ATTO 594 Biotin is a biotin derivative of ATTO 594 with maximum excitation/emission wavelengths: 603/626 nm.
|
-
- HY-D1964
-
|
Fluorescent Dyes/Probes
|
ATTO 633 Biotin is a biotin derivative of ATTO 633 with maximum excitation/emission wavelengths: 630/651 nm.
|
-
- HY-D1965
-
|
Fluorescent Dyes/Probes
|
ATTO 700 Biotin is a biotin derivative of ATTO 700 with maximum excitation/emission wavelengths: 700/716 nm.
|
-
- HY-D1978
-
|
Fluorescent Dyes/Probes
|
ATTO 610 Biotin is a biotin derivative of ATTO 610 with maximum excitation/emission wavelengths: 616/633 nm.
|
-
- HY-D1988
-
|
Fluorescent Dyes/Probes
|
ATTO 620 Biotin is a biotin derivative of ATTO 620 with maximum excitation/emission wavelengths: 620/642 nm.
|
-
- HY-D1989
-
|
Fluorescent Dyes/Probes
|
ATTO 725 Biotin is a biotin derivative of ATTO 725 with maximum excitation/emission wavelengths: 728/751 nm.
|
-
- HY-D1996
-
|
Fluorescent Dyes/Probes
|
ATTO 647 Biotin is a biotin derivative of ATTO 647 with maximum excitation/emission wavelengths: 630/651 nm.
|
-
- HY-D2003
-
|
Fluorescent Dyes/Probes
|
ATTO 565 biotin is a biotin derivative of ATTO 565 with maximum excitation/emission wavelengths: 564/590 nm.
|
-
- HY-D2007
-
|
Fluorescent Dyes/Probes
|
ATTO 488 biotin is a biotin derivative of ATTO 488 with maximum excitation/emission wavelengths: 500/520 nm.
|
-
- HY-D2025
-
|
Fluorescent Dyes/Probes
|
ATTO 550 biotin is a biotin derivative of ATTO 550 with maximum excitation/emission wavelengths: 554/576 nm.
|
-
- HY-D2076
-
|
Fluorescent Dyes/Probes
|
ATTO 740 biotin is a biotin derivative of ATTO 740 with maximum excitation/emission wavelengths: 743/763 nm.
|
-
- HY-D2031
-
|
Fluorescent Dyes/Probes
|
ATTO 514 biotin is a biotin derivative of ATTO 514 with maximum excitation/emission wavelengths: 511/531 nm.
|
-
- HY-D2049
-
|
Fluorescent Dyes/Probes
|
ATTO 532 biotin is a biotin derivative of ATTO 532 with maximum excitation/emission wavelengths: 532/552 nm.
|
-
- HY-D1911
-
|
Fluorescent Dyes/Probes
|
ATTO 665 Biotin is a biotin derivative of ATTO 665 with maximum excitation/emission wavelengths: 663/680 nm.
|
-
- HY-D2065
-
|
Fluorescent Dyes/Probes
|
ATTO 680 biotin is a biotin derivative of ATTO 680 with maximum excitation/emission wavelengths: 681/698 nm.
|
-
- HY-133376
-
|
Dyes
|
DBCO-NHCO-PEG12-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG12-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D1870
-
|
Dyes
|
Sulfo-Cy3-PEG3-biotin potassium is a biotin-modified derivative of Cy3 (Cyanine3) (HY-D0822) dye containing a TCO group. The TCO group of Sulfo-Cy3-PEG3-biotin potassium reacts with the tetrazine functional group in highly specific click chemistry to form a covalent bond. Thus, Sulfo-Cy3-PEG3-biotin potassium can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples. And because it is labeled with biotin, it is often used in affinity chromatography experiments, such as immunoprecipitation.
|
-
- HY-D1923
-
|
Fluorescent Dyes/Probes
|
ATTO 390 biotin is a biotin derivative of ATTO 390, used for streptavidin reaction, maximum excitation/emission wavelength: 390/476 nm.
|
-
- HY-D1927
-
|
Fluorescent Dyes/Probes
|
ATTO 425 Biotin is a biotin derivative of ATTO 425, used for streptavidin reaction, the maximum excitation emission wavelength: 439/489 nm.
|
-
- HY-D2226
-
-
- HY-D1403
-
|
Protein Labeling
|
L-Biotin-NH-5MP is a biotin-conjugated 5-Methylene pyrrolone (5MP). 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation .
|
-
- HY-D1695
-
-
- HY-D1406
-
|
Protein Labeling
|
L-Biotin-NH-5MP-Br is a biotin-conjugated 5-Methylene pyrrolone (5MP). 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation .
|
-
- HY-D1804
-
|
Dyes
|
Vari Fluor 680-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=680 nm/701 nm.
|
-
- HY-D1805
-
|
Dyes
|
Vari Fluor 647-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=650 nm/665 nm.
|
-
- HY-D1806
-
|
Dyes
|
Vari Fluor 594-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=590 nm/617 nm.
|
-
- HY-D1807
-
|
Dyes
|
Vari Fluor 555-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=555 nm/565 nm.
|
-
- HY-D1808
-
|
Dyes
|
Vari Fluor 488-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=490 nm/515 nm.
|
-
- HY-D1809
-
|
Dyes
|
Vari Fluor 405-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=405 nm/431 nm.
|
-
- HY-D1919
-
|
Fluorescent Dyes/Probes
|
ATTO 390 amine is a biotin derivative of ATTO 390 with maximum excitation/emission wavelengths: 390/476 nm.
|
- HY-D2170
-
|
Fluorescent Dyes/Probes
|
AF488 streptavidin is a fluorescence labeled streptavidin. AF488 streptavidin comprises a biotin-binding protein (streptavidin) covalently attached to a fluorescent label (AF488). AF488 is a bright, photostable green fluorophore .
|
- HY-D1687
-
|
Fluorescent Dyes/Probes
|
Flubi-2 is a fluorescein-biotin based pH-ratio dye (Ex=480 nm, Em= 520-560 nm) with a pK value of 6.7. Flubi-2 is a hydrolysis product of Flubida-2 (non-fluorescent, membrane permeable). Flubi-2 can be used for pH determination of organelles of the secretory pathway (such as golgi apparatus and endoplasmic reticulum) in living cells .
|
Cat. No. |
Product Name |
Type |
-
- HY-100894
-
|
Cell Assay Reagents
|
Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates.
|
-
- HY-D0980
-
Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin
|
Biochemical Assay Reagents
|
Biotin-DADOO is a biotinylation reagent, which can be used to synthesize a biotin-estradiol conjugate (i.e., biotin-DADOO-estradiol) to develop a direct, broad range enzyme immunoassay to measure plasma estradiol concentrations.
|
-
- HY-157920
-
N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine
|
Biochemical Assay Reagents
|
Biotin-PE-maleimide (N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine) is a bulky, membrane-impermeable, sulfhydryl-containing reagent with a relatively large molecular size. Biotin-PE-maleimide can be used for biotin labeling (such as thiol groups) and detection of proteins or other biomolecules .
|
-
- HY-125501
-
Biotin-(AC5)2-hydrazide
|
Biochemical Assay Reagents
|
Biotin-XX hydrazide (Biotin-(AC5)2-hydrazide) is a carbonyl-reactive biotinylation reagent which contains two aminohexanoic acid spacers. Biotin-XX hydrazide has higher efficiency of avidin-binding .
|
-
- HY-156145
-
-
- HY-100215
-
-
- HY-136769
-
|
Biochemical Assay Reagents
|
Biotin-HPDP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-129832
-
N-(3-Azidopropyl)Biotinamide
|
Biochemical Assay Reagents
|
Biotin-azide (N-(3-Azidopropyl)biotinamide) is a form of biotin with a terminal azide group. Biotin-azide can be used to prepare various biotinylated conjugates via Click Chemistry . Biotin-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-101885
-
Biotinamidocaproyl hydrazide; BACH; (+)-Biotinamidohexanoic Acid hydrazide; Biotin Aminocaproyl Hydrazide
|
Biochemical Assay Reagents
|
Biotin LC hydrazide is a long chain protein modification reagent, which can transform periodate-oxidized glycoproteins.
|
-
- HY-157919
-
N-6-(Biotinylamino)hexanoyl-N'-[2-(N-maleimido)ethyl]piperazine, hydrochloride
|
Biochemical Assay Reagents
|
Biotin-PEAC5-maleimide hydrochloride is a biochemical assay reagent, and can be used in biotin-PEAC5-maleimide (BPM)-labeling assay to assess modification of protein thiols by electrophiles .
|
-
- HY-131455A
-
|
Biochemical Assay Reagents
|
Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 TFA is used for detection of modification site for N-myristoylated and GPI-anchored proteins in blood-stage P. falciparum . Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 (TFA) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-147207A
-
|
Drug Delivery
|
Phospholipid-PEG-Biotin (MW 2000) is a Biotin labeled phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic “head” and two hydrophobic “tails”; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein .
|
-
- HY-D0183
-
|
Enzyme Substrates
|
ATP-polyamine-biotin, the first cell-permeable ATP analogue, is an efficient kinase cosubstrate. ATP-polyamine-biotin promotes biotin labeling of kinase substrates in live cells .
|
-
- HY-147207C
-
|
Drug Delivery
|
Phospholipid-PEG-Biotin (MW 5000) is a phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic “head” and two hydrophobic “tails”; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein .
|
-
- HY-147207
-
|
Drug Delivery
|
Phospholipid-PEG-Biotin (MW 1000) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
-
- HY-147207B
-
|
Drug Delivery
|
Phospholipid-PEG-Biotin (MW 3400) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
-
- HY-147207D
-
|
Drug Delivery
|
Phospholipid-PEG-Biotin (MW 10000) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
-
- HY-147207E
-
|
Drug Delivery
|
Phospholipid-PEG-Biotin (MW 20000) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
-
- HY-W441000
-
|
Drug Delivery
|
DSPE-Biotin is a lipid. DSPE-Biotin can be used for the research of various biochemical .
|
-
- HY-W127773
-
|
Biochemical Assay Reagents
|
KNI-1293 Biotin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-140736
-
|
Drug Delivery
|
DSPE-PEG-Biotin, MW 2000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140736B
-
|
Drug Delivery
|
DSPE-PEG-Biotin, MW 5000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-P3152
-
|
Native Proteins
|
Streptavidin is a ∼60 kDa homotetramer. Streptavidin binds four molecules of biotin with the highest affinity. The binding affinity of biotin to streptavidin is one of the highest reported for a non-covalent interaction to date, with a KD ∼ 0.01 pM . Streptavidin has an immunosuppressive role .
|
-
- HY-W440886
-
|
Drug Delivery
|
DSPE-PEG-Biotin, MW 3400 is a phospholipid PEG for biotinylation. The amphiphilic property of the DSPE-PEG is useful for precision drug delivery and cancer therapy.
|
-
- HY-157916
-
Aldehyde reactive probe
|
Biochemical Assay Reagents
|
ARP (Aldehyde reactive probe) is an aldehyde reactive probe for detecting abasic site (common DNA lesions and intermediates in mutagenesis and carcinogenesis) in DNA, which specificially tags AP site with biotin residues. ARP is highly sensitive with a femtomolar-level basic site detection capabilities (less than one site per 10 4 nucleotides) .
|
-
- HY-156144
-
DBB chloride
|
Gene Sequencing and Synthesis
|
p-Diazobenzoyl-biocytin chloride is a biotin derivative that can be used for the labeling of tyrosine and histidines in peptides and proteins .
|
-
- HY-156146
-
-
- HY-P2989
-
|
Biochemical Assay Reagents
|
Pyruvate carboxylase is a biotin-containing enzyme that catalyzes the HCO3 − and MgATP dependent carboxylation of pyruvate to form oxaloacetate. Pyruvate carboxylase plays an essential role in controlling whole-body energetics through regulation of gluconeogenesis in the liver, synthesis of fatty acids in adipocytes, and insulin secretion in pancreatic β cells .
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-
- HY-144012A
-
DPPE-PEG350; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Drug Delivery
|
16:0 PEG350 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144012B
-
DPPE-PEG550; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Drug Delivery
|
16:0 PEG550 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144012C
-
DPPE-PEG750; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium
|
Drug Delivery
|
16:0 PEG750 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013A
-
DSPE-mPEG350 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Drug Delivery
|
18:0 mPEG350 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013B
-
DSPE-mPEG550 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Drug Delivery
|
18:0 mPEG550 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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-
- HY-144013C
-
DSPE-mPEG750 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium
|
Drug Delivery
|
18:0 mPEG750 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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-
- HY-144012D
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DPPE-PEG1000; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Drug Delivery
|
16:0 PEG1000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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-
- HY-144012E
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DPPE-PEG3000; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Drug Delivery
|
16:0 PEG3000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144012H
-
DPPE-PEG5000; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Drug Delivery
|
16:0 PEG5000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013D
-
DSPE-mPEG1000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Drug Delivery
|
18:0 mPEG1000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013E
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DSPE-mPEG3000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Drug Delivery
|
18:0 mPEG3000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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-
- HY-144013H
-
DSPE-mPEG5000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Drug Delivery
|
18:0 mPEG5000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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-
- HY-155924
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DMPE-PEG350; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Drug Delivery
|
14:0 PEG350 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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-
- HY-155925
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DMPE-PEG550; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Drug Delivery
|
14:0 PEG550 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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-
- HY-155926
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DMPE-PEG750; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium
|
Drug Delivery
|
14:0 PEG750 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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-
- HY-155927
-
DMPE-PEG1000; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Drug Delivery
|
14:0 PEG1000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155928
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DMPE-PEG3000; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Drug Delivery
|
14:0 PEG3000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155929
-
DMPE-PEG5000; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Drug Delivery
|
14:0 PEG5000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155930
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DOPE-PEG350; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Drug Delivery
|
18:1 PEG350 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155931
-
DOPE-PEG550; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Drug Delivery
|
18:1 PEG550 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155932
-
DOPE-PEG1000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Drug Delivery
|
18:1 PEG1000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155933
-
DOPE-PEG3000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Drug Delivery
|
18:1 PEG3000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155934
-
DOPE-PEG5000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Drug Delivery
|
18:1 PEG5000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P2546
-
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Neurokinin Receptor
|
Neurological Disease
|
Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .
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- HY-P2136F
-
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Apoptosis
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Neurological Disease
Inflammation/Immunology
Cancer
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Biotin-COG1410 TFA is a biotin labled COG1410 (HY-P2136). COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological disease .
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-
- HY-P2549
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-
- HY-P2551
-
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Amyloid-β
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Neurological Disease
|
Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-ß-(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via post-translational processing of amyloid precursor protein (APP) .
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-
- HY-P3576
-
|
Fluorescent Dye
|
Neurological Disease
Cancer
|
Biotin-Gastrin Releasing Peptide, human is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .
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-
- HY-17571F
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Biotin-α-Hypophamine; Biotin-Oxytocic hormone
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Peptides
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Others
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Biotin-Oxytocin (Biotin-α-Hypophamine; Biotin-Oxytocic hormone) is a biological active peptide. (This is Oxytocin (HY-17571) N-terminally labeled with Biotin.)
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-
- HY-13948F
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Biotin-Ahx-Angiotensin II; Biotin-Ahx-Ang II; Biotin-Ahx-DRVYIHPF
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Peptides
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Others
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Biotin-Ahx-Angiotensin II human (Biotin-Ahx-Angiotensin II; Biotin-Ahx-Ang II; Biotin-Ahx-DRVYIHPF) is a biological active peptide. (biotin labeled HY-13948)
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-
- HY-P0206F
-
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Peptides
|
Others
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biotin-Bradykinin is a biological active peptide. (Biotin labeled HY-P0206)
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-
- HY-P0286F
-
|
Peptides
|
Others
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Biotin-OVA (323-339) is a biological active peptide. (Biotin labeled HY-P0286)
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-
- HY-P1264F1
-
|
nAChR
|
Neurological Disease
|
Biotin-α-Bungarotoxin is the Biotin labelled α-Bungarotoxin (HY-P1264). α-Bungarotoxin is a competitive antagonist at nicotinic acetylcholine receptors (nAChRs) .
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-
- HY-P2467
-
|
Fluorescent Dye
|
Metabolic Disease
|
Biotin-TAT (47-57), a biotin tagged TAT, is a transactivator of transcription. Biotin-TAT (47-57) is one of the most widely used protein transduction domains (PTDs) into different primary cells is ATP- and temperature-dependent, indicating the involvement of endocytosis .
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-
- HY-P0315F
-
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Peptides
|
Others
|
Biotin-Crosstide is abiotinylated Crosstide (HY-P0315).
|
-
- HY-P5831
-
|
Peptides
|
Cancer
|
Biotin-H10 is a specific anterior gradient homolog 2 (AGR2) inhibitor with a KD of 6.4 nM. Biotin-H10 inhibits cancer cells viability .
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-
- HY-P4869
-
-
- HY-P5347
-
-
- HY-P1468F
-
Biotin-amyloid β-protein (1-28)
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Amyloid-β
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Others
|
Biotin-β-amyloid (1-28) (Biotin-amyloid β-protein (1-28)) is abiotinylated β-Amyloid (1-28) (HY-P1468).
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-
- HY-P0265F
-
|
Peptides
|
Others
|
Biotin-Ahx-β-Amyloid (1-40) is a biological active peptide. (Biotin labled HY-P0265)
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-
- HY-P1097F
-
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Peptides
|
Others
|
Biotin-Gastrin-1, human (1-17) is a biological active peptide. (Biotin-labeled HY-P1097)
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-
- HY-P3657A
-
|
Fluorescent Dye
|
Cancer
|
Biotin-KKKRKV acetate is the biotinylated KKKRKV acetate. KKKRKV is a nuclear localization signal (NLS) peptide derived from simian virus 40 .
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-
- HY-P5830
-
|
Caspase
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Others
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Biotin-DEVD-CHO can be used for affinity labeling of Caspase-8 following in vitro caspase cleavage .
|
-
- HY-P3861
-
|
Neurokinin Receptor
|
Neurological Disease
|
Biotin-NeurokininA is a biotinylated NeurokininA (HY-P0197). Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues .
|
-
- HY-P1363F1
-
Biotin-amyloid β-peptide (1-42) (human) TFA
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Amyloid-β
|
Neurological Disease
|
Biotin-β-Amyloid (1-42), human TFA (Biotin-Amyloid β-Peptide (1-42) (human) TFA) is the botin labeled β-Amyloid (1-42), human TFA (HY-P1363). β-Amyloid (1-42), human TFA is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .
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-
- HY-P3623
-
|
Fluorescent Dye
|
Others
|
Biotin-Glucagon-Like Peptide 1 (7-36) amide, human is a biologically active peptide. Biotin-Glucagon-Like Peptide 1 (7-36) amide, human can be used for the research of various biochemical studies.
|
-
- HY-P3828
-
|
Fluorescent Dye
|
Neurological Disease
|
Biotin-myelin basic protein (94-102) is a peptide fragemt. Myelin basic protein is responsible for adhesion of the cytosolic surfaces of multilayered compact myelin, it plays an important role in the process of myelination of nerves in the nervous system. Myelin basic protein also acts as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin .
|
-
- HY-P3844
-
-
- HY-P1032F
-
|
Endogenous Metabolite
|
Endocrinology
|
Biotinyl-Angiotensin I (human, mouse, rat) is biotin-labeled Angiotensin I . Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE) .
|
-
- HY-13443F
-
|
Peptides
|
Others
|
Exendin 4, biotin labeled is a biological active peptide. (Biotin labeled HY-13443)
|
-
- HY-P4078
-
|
Peptides
|
Others
|
(Arg)9 biotin labeled is a cell-permeable peptide. (Arg)9 biotin labeled can be used for drug delivery. (Arg)9 biotin labeled can traverse the plasma membrane of eukaryotic cells .
|
-
- HY-P2504
-
|
Syk
|
Others
|
Syk Kinase Peptide Substrate, Biotin labeled is a biotin-labled Syk kinase peptide substrate.
|
-
- HY-P5351
-
|
Peptides
|
Others
|
Hyaluronan-binding peptide, biotin labeled is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.)
|
-
- HY-P2491
-
|
Fluorescent Dye
|
Cardiovascular Disease
Endocrinology
|
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .
|
-
- HY-P2510
-
|
Thyroid Hormone Receptor
|
Metabolic Disease
|
Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor, can be used for analyzing the interaction between parathyroid hormone and parathyroid hormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns .
|
-
- HY-P1405
-
-
- HY-P2609F
-
|
PACAP Receptor
|
Others
|
PACAP (1-38), amide, Biotin-labeled is a biological active peptide. (Biotin-labeled HY-P0221)
|
-
- HY-W010721
-
-
- HY-P3616
-
|
GCGR
|
Metabolic Disease
|
Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide is a biotin labeled glucagon-like peptide-1-(7-36). Glucagon-like peptide-1-(7-36) is a gastrointestinal peptide with antidiabetogenic activity, and can increase the release of insulin .
|
-
- HY-P2535
-
|
GLP Receptor
|
Metabolic Disease
|
Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human is an C-terminal-labelled biotinylated GLP-1 (7-36) amide.
|
-
- HY-P2989
-
|
Endogenous Metabolite
|
Metabolic Disease
|
Pyruvate carboxylase is a biotin-containing enzyme that catalyzes the HCO3 − and MgATP dependent carboxylation of pyruvate to form oxaloacetate. Pyruvate carboxylase plays an essential role in controlling whole-body energetics through regulation of gluconeogenesis in the liver, synthesis of fatty acids in adipocytes, and insulin secretion in pancreatic β cells .
|
-
- HY-K3004
-
1 Publications Verification
|
RPMI 1640 contains glutathione and high concentration of vitamins, also contains biotin, vitamin B12, 4-Aminobenzoic acid (PABA) not found in MEM and DMEM, as well as high concentration of inositol and choline chloride.
|
-
- HY-K0218A
-
1 Publications Verification
|
MCE Streptavidin Agarose 6FF, a 6% highly cross-linked agarose reagent coupled with recombinant streptavidin, is an affinity chromatography medium for separation and purification of biotinylated peptides, antibodies, lectins, etc. The total binding capacity of Streptavidin Agarose 6FF is more than 200 nmol of D-Biotin/mL settled resin.
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
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Product Name |
Species |
Source |
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Source |
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Tag |
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Accession |
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Gene ID |
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Molecular Weight |
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Endotoxin Level |
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Formulation |
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Storage & Stability |
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Free Sample |
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* This product has been "discontinued".
Optimized version of product available:
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Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B0511S
-
|
Biotin-d2-1 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
|
-
-
- HY-B0511S1
-
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rel-Biotin-d4 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
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-
-
- HY-B0511S2
-
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Biotin-d2 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
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Cat. No. |
Product Name |
Application |
Reactivity |
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- HY-P80949
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WB, IHC-F, IHC-P, ELISA, ICC/IF
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Mouse |
Biotin-conjugated Anti-Mouse IgG H&L is a Biotin-conjugated and Goat origined monoclonal antibody, targeting to Mouse IgG antibody. Biotin-conjugated Anti-Mouse IgG H&L can binds to the light and heavy chains of Mouse IgG antibodies, thus can be used for WB, IHC-F, IHC-P, ELISA, ICC/IF assays in the background of Mouse.
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- HY-P80953
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WB, IHC-F, IHC-P, ELISA, ICC/IF
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Rabbit |
Biotin-conjugated Anti-Rabbit IgG H&L is a Biotin-conjugated and Goat origined monoclonal antibody, targeting to Rabbit IgG antibody. Biotin-conjugated Anti-Rabbit IgG H&L can binds to the light and heavy chains of Rabbit IgG antibodies, thus can be used for WB, IHC-F, IHC-P, ELISA, ICC/IF assays in the background of Rabbit.
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Cat. No. |
Product Name |
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Classification |
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- HY-151714
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Tetrazine
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Biotin-MeTz shiyi is a click chemistry reagent with a terminal methyltetrazine group. Biotin-MeTz shiyi, as a biotin derivative, can be used for the preparation of biotinylated conjugates .
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- HY-156497
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- HY-147206A
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Alkynes
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Biotin-PEG-Alk (MW 1000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 1000) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-147206B
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Alkynes
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Biotin-PEG-Alk (MW 2000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 2000) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-147206C
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Alkynes
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Biotin-PEG-Alk (MW 3400) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 3400) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-147206E
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Alkynes
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Biotin-PEG-Alk (MW 10000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 10000) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-147206F
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Alkynes
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Biotin-PEG-Alk (MW 20000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 20000) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130143
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PROTAC Synthesis
Azide
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Biotin-PEG3-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-138749
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Alkynes
PROTAC Synthesis
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Biotin alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-147206
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Alkynes
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Biotin-PEG-Alk (MW 600) is a Biotin-labeled Alkyne functionalized polyethylene glycol. Biotin-PEG-Alk (MW 600) can be used to modify proteins, peptides, and oligonucleotides . Biotin-PEG-Alk (MW 600) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140922
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PROTAC Synthesis
Alkynes
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Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-151672
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Azide
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Biotin-TEG-ATFBA is a click chemistry reagent containing a perfluorophenylazide group. Biotin-TEG-ATFBA forms a highly stable azene intermediate that undergoes insertion and addition reactions (non-intermolecular rearrangement) in moderate to good yields after photolysis.
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- HY-151741
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Labeling and Fluorescence Imaging
Tetrazine
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Biotin-PEG4-MeTz is a click chemistry reagent containing a terminal methyltetrazine group that reacts with trans-cyclooctene. Biotin-PEG4-MeTz can be used for the preparation of biotinylated conjugates .
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- HY-151649
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Alkynes
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Biotin-PEG(4)-SS-Alkyne is a click chemistry reagent containing an alkyne group. Biotin-PEG(4)-SS-Alkyne can be used for the research of various biochemical .
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- HY-151670
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Azide
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Biotin-PEG(4)-SS-Azide is a click chemistry reagent containing an azide group. Biotin-PEG(4)-SS-Azide can be used for the research of various biochemical .
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- HY-140910
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Azide
PROTAC Synthesis
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Biotin-PEG4-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-140911
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PROTAC Synthesis
Azide
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Biotin-PEG6-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-156379
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- HY-129832
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N-(3-Azidopropyl)Biotinamide
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Azide
Labeling and Fluorescence Imaging
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Biotin-azide (N-(3-Azidopropyl)biotinamide) is a form of biotin with a terminal azide group. Biotin-azide can be used to prepare various biotinylated conjugates via Click Chemistry . Biotin-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-138503
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Alkynes
PROTAC Synthesis
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Biotin-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-139107
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ADC Synthesis
Azide
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Biotin-PEG4-SS-azide is a cleavable, biotin-labeled, ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biotin-PEG4-SS-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-140940
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Tetrazine
PROTAC Synthesis
|
Biotin-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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-
- HY-147206D
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Alkynes
PROTAC Synthesis
|
Biotin-PEG-Alk (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG-Alk (MW 5000) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-156495
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|
|
Tetrazine
Labeling and Fluorescence Imaging
|
Biotin-PEG3-Me-Tet is an ADC Linker containing 3 PEG units. Biotin-PEG3-Me-Tet can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
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-
- HY-140923
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Alkynes
PROTAC Synthesis
|
Biotin-PEG4-amide-Alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-amide-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-W250928A
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Azide
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Biotin-PEG-azide (MW 600) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
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- HY-W250928B
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|
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Azide
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Biotin-PEG-azide (MW 1000) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
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- HY-W250928E
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Azide
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Biotin-PEG-azide (MW 5000) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
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-
- HY-151667
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DecarboxyBiotin-N3
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|
Azide
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Biotin-C5-Azide (DecarboxyBiotin-N3) is a biotin reagent and can be used to prepare biotinylated conjugates . Biotin-C5-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-126957
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Azide
PROTAC Synthesis
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Biotin-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Biotin-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-133174
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PROTAC Synthesis
Azide
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Biotin-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Biotin-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-133175
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Azide
PROTAC Synthesis
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Biotin-PEG7-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Biotin-PEG7-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-140913
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Azide
PROTAC Synthesis
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Biotin-PEG23-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG23-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-140912
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Azide
PROTAC Synthesis
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Biotin-PEG11-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG11-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-W096133
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ADC Synthesis
Azide
|
Biotin-PEG1-azide is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Biotin-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-113828
-
|
|
PROTAC Synthesis
Alkynes
|
Biotin-PEG2-C4-alkyne is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Biotin-PEG2-C4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-140915
-
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Azide
PROTAC Synthesis
|
Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-Picolyl azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-141091
-
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Azide
ADC Synthesis
|
Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Biotin-PEG4-Dde-TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-140944
-
|
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ADC Synthesis
Azide
|
Biotin-PEG3-SS-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Biotin-PEG3-SS-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-140131
-
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Alkynes
PROTAC Synthesis
|
Biotin-PEG4-PC-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-PC-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-117042
-
|
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PROTAC Synthesis
Azide
|
Biotin-PEG2-C6-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Biotin-PEG2-C6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-133458
-
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PROTAC Synthesis
Azide
|
Biotin-PEG3-amido-SS-amido-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG3-amido-SS-amido-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-140914
-
|
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Azide
PROTAC Synthesis
|
Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-Amide-C6-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-140928
-
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Alkynes
PROTAC Synthesis
|
Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-135912
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|
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PROTAC Synthesis
Azide
|
Biotin-PEG2-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG2-CH2CH2N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-140921
-
|
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Azide
PROTAC Synthesis
|
Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-131455A
-
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Azide
|
Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 TFA is used for detection of modification site for N-myristoylated and GPI-anchored proteins in blood-stage P. falciparum . Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 (TFA) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-130809
-
|
|
DBCO
|
DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction . DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-141183
-
|
|
TCO
|
TCO-PEG4-biotin is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-136050
-
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|
TCO
ADC Synthesis
|
TCO-PEG3-Biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG3-Biotin is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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- HY-136053
-
|
|
ADC Synthesis
Tetrazine
|
Tetrazine-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130924
-
|
|
ADC Synthesis
BCN
|
BCN-PEG3-Biotin is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG3-Biotin is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-135939
-
|
|
DBCO
PROTAC Synthesis
|
DBCO-NHCO-PEG2-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG2-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-135958
-
|
|
DBCO
PROTAC Synthesis
|
DBCO-NHCO-PEG6-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG6-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-133376
-
|
|
PROTAC Synthesis
DBCO
|
DBCO-NHCO-PEG12-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG12-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-123916
-
|
|
PROTAC Synthesis
DBCO
|
DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140136
-
|
|
ADC Synthesis
DBCO
|
PC DBCO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC DBCO-PEG3-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-135979
-
|
|
DBCO
ADC Synthesis
|
DBCO-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-SS-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-136095
-
|
|
Tetrazine
ADC Synthesis
|
Tetrazine-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136035
-
|
|
ADC Synthesis
Tetrazine
|
Methyltetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-SS-PEG4-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136036
-
|
|
ADC Synthesis
Tetrazine
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Tetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-PEG4-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-136078
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ADC Synthesis
Tetrazine
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Tetrazine-diazo-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-diazo-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-140128
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DBCO
PROTAC Synthesis
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DBCO-S-S-PEG3-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-S-S-PEG3-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-136031
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Tetrazine
ADC Synthesis
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Tetrazine-SS-Biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-130810
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DBCO
ADC Synthesis
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DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-Link-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140927
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UV Cleavable Biotin-PEG2-alkyne
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PROTAC Synthesis
Alkynes
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Azido-C3-UV-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-C3-UV-biotin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140127
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Azide
ADC Synthesis
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Azide-C2-SS-C2-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azide-C2-SS-C2-biotin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140947
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PROTAC Synthesis
Azide
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TAMRA-Azide-PEG-biotin is a dye derivative of TAMRA (HY-135640). TAMRA-Azide-PEG-biotin contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140924
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Alkynes
PROTAC Synthesis
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Dde Biotin-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140931
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DBCO
PROTAC Synthesis
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Dde Biotin-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140925
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Alkynes
PROTAC Synthesis
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Diazo Biotin-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Diazo Biotin-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140137
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DBCO
PROTAC Synthesis
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WSPC Biotin-PEG3-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . WSPC Biotin-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140877
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Alkynes
PROTAC Synthesis
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Dde Biotin-PEG4-TAMRA-PEG4 Alkyne is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Dde Biotin-PEG4-TAMRA-PEG4 Alkyne contains Alkyne groups that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140930
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ADC Synthesis
DBCO
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Diazo Biotin-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Diazo Biotin-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140130
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ADC Synthesis
Alkynes
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PC Biotin-PEG3-alkyne is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC Biotin-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140918
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Azide
PROTAC Synthesis
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Diazo Biotin-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Diazo Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140916
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PROTAC Synthesis
Azide
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Dde Biotin-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140132
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Azide
ADC Synthesis
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PC Biotin-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140920
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Azide
PROTAC Synthesis
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UV Cleavable Biotin-PEG2-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . UV Cleavable Biotin-PEG2-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140917
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Azide
PROTAC Synthesis
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Dde Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-Picolyl azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140582
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DBCO
PROTAC Synthesis
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N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140133
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Azide
ADC Synthesis
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PC-Biotin-PEG4-PEG3-azide is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC-Biotin-PEG4-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-W110146
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- HY-140581
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PROTAC Synthesis
Azide
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N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-127112
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Alkynes
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Oleic acid alkyne is oleic acid with an acetylene group. The terminal alkyne group can be used for click chemical ligation reactions. Oleic acid can be hydroxylated by a microsomal cytochrome P-450-dependent system (ω-OAH). Through click chemistry reactions, fluorescent or biotin-labeled oleic acid can be introduced to analyze its metabolism and biological activity.
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- HY-112295
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Azide
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AzKTB is a capture reagent which bears a short trypsin-cleavable peptide sequence between the azide module and the TAMRA/PEG-biotin labels. AzKTB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-131442
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Alkyne tyramide; Alk-Ph
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Alkynes
Labeling and Fluorescence Imaging
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Alkyne-phenol (Alk-Ph) is a clickable ascorbate peroxidase 2 (APEX2) probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP). Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins . Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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