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Results for "

C-29

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

3

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100461
    C29
    65+ Cited Publications

    		 Toll-like Receptor (TLR) Inflammation/Immunology
    C29 is a Toll-like receptor 2 (TLR2) inhibitor. C29 blocks hTLR2/1 and hTLR2/6 signaling with IC50s of 19.7 and 37.6 μM, respectively .
    <em>C29</em>
  • HY-N6061
    Ophiopogonin C

    		Others Cancer
    Ophiopogonin C, isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin C shows cytotoxic activity against two human tumor cell lines MG-63 and SNU387 with IC50s of 19.76 μM and 15.51 μM, respectively .
    Ophiopogonin C
  • HY-N3504
    Ophiopogonin D'

    		Sirtuin Cancer
    Ophiopogonin D', isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D' shows cytotoxic activity against two human tumor cell lines MG-63 and SNU387 with IC50s of 3.09 μM and 3.63 μM, respectively . Ophiopogonin D' activates SIRT1 in a dose-dependent manner .
    Ophiopogonin D'
  • HY-N0515
    Ophiopogonin D

    		PPAR NF-κB Calcium Channel Cardiovascular Disease Inflammation/Immunology
    Ophiopogonin D, isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside . Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca 2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D has been used to treat inflammatory and cardiovascular diseases for thousands of years .
    Ophiopogonin D
  • HY-N1962
    Ophiopojaponin C

    Ophiopojaponin C is a naturally occurring C29 steroidal glycoside isolated from the tubers of O. japonicas .
    Ophiopojaponin C

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