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C5

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  • HY-P700862
    Complement C5/C5a Protein, Human (HEK293, His)

    Complement C5; C5; CPAMD4; ECLZB; C5a; C5b; C5D

    		 Human HEK293
    Activated by a C5 convertase, Complement C5 induces the assembly of C5-C9, forming the membrane attack complex. The transient C6 binding site on C5b is pivotal for lytic complex formation. C5 proteolytic degradation yields C5a anaphylatoxin, a local inflammatory mediator. Interacting with C5AR1, C5a induces diverse responses, including calcium release, muscle contraction, vascular permeability, and histamine release. As a potent chemokine, C5a guides leukocyte migration to inflammation sites, orchestrating immune responses. Complement C5/C5a Protein, Human (HEK293, His) is the recombinant human-derived Complement C5/C5a protein, expressed by HEK293, with C-His labeled tag. The total length of Complement C5/C5a Protein, Human (HEK293, His) is 1658 a.a., with molecular weight of 110-114 kDa (α chain) & 69-73 kDa (β chain), respectively.
  • HY-P7695
    Complement C5/C5a Protein, Mouse
    4 Publications Verification

    rMuC5a; Complement C5; Hemolytic Complement; C5a

    		 Mouse E. coli
    Complement C5/C5a Protein, Mouse is a recombinant mouse complement component 5a (C5a). C5a is a potent pro-inflammatory mediator and acts as an essential part of the innate immune response.
  • HY-P71719
    Complement C5/C5a Protein, Pig (P.pastoris, His)

    C5; Complement C5a anaphylatoxin

    		 Pig P. pastoris
    Complement C5/C5a Protein, a component of the complement system, is involved in the immune response and inflammation. It is cleaved to generate C5a, a potent pro-inflammatory mediator. Complement C5/C5a Protein's role in immune regulation and its potential as a therapeutic target make it a promising candidate for the treatment of inflammatory disorders and autoimmune diseases. Complement C5/C5a Protein, Pig (P.pastoris, His) is the recombinant pig-derived Complement C5/C5a protein, expressed by P. pastoris , with N-His labeled tag. The total length of Complement C5/C5a Protein, Pig (P.pastoris, His) is 74 a.a., with molecular weight of ~10.6 kDa.
  • HY-P700959
    Complement C5/C5a Protein, Human (His)

    C5a; Complement C5; C5; CPAMD4; ECLZB

    		 Human E. coli
    Complement C5 is activated by C5 convertase, inducing C5-C9 assembly to form the membrane attack complex. The transient C6 binding site on C5b is critical for the formation of the cleavage complex. Complement C5/C5a Protein, Human (His) is the recombinant human-derived Complement C5/C5a protein, expressed by E. coli , with N-His labeled tag. The total length of Complement C5/C5a Protein, Human (His) is 74 a.a., with molecular weight of 13-14 kDa.
  • HY-P77540
    Complement C5/C5a Protein, Mouse (Biotinylated)

    Complement C5; Hemolytic Complement; C5a

    		 Mouse E. coli
    Complement C5/C5a Protein activates late complement components to form the membrane attack complex, C5-C9. C5b binds C6, initiating lytic complex assembly. C5a, produced by C5 degradation, acts as an anaphylatoxin, inducing local inflammation. C5a stimulates intracellular calcium release, smooth muscle contraction, vascular permeability, histamine release, and acts as a chemokine, guiding leukocyte migration. Complement C5/C5a Protein, Mouse (Biotinylated) is the recombinant mouse-derived Complement C5/C5a protein, expressed by E. coli, with tag free. The total length of Complement C5/C5a Protein, Mouse (Biotinylated) is 77 a.a., with molecular weight of ~9 KDa.
  • HY-P7864
    Complement C5/C5a Protein, Human

    rHuComplement C5/C5a; Complement C5; C5a anaphylatoxin; C5a

    		 Human E. coli
    Complement C5/C5a Protein, Human is a recombinant human complement C5a. C5a is a 74-amino acid glycoprotein generated on activation of the C system. Complement C5 is cleaved by proteolysis in the terminal phase of complement activation generating the pro-inflammatory C5a and membrane attack complex nucleator C5b. C5a is an inflammatory mediator generated by complement activation that positively regulates various arms of immune defense, including Toll-like receptor 4 (TLR4) signaling.
  • HY-P78595
    Complement C5/C5a Protein, Cynomolgus

    C5a; Complement Component 5a

    		 Cynomolgus E. coli
    Complement C5 is activated by C5 convertase, inducing C5-C9 assembly to form the membrane attack complex. The transient C6 binding site on C5b is critical for the formation of the cleavage complex. Complement C5/C5a Protein, Cynomolgus is the recombinant cynomolgus-derived Complement C5/C5a protein, expressed by E. coli , with tag free. The total length of Complement C5/C5a Protein, Cynomolgus is 74 a.a., with molecular weight of ~11 kDa.
  • HY-P700398
    C5AR1 Protein-VLP, Human (HEK293, His)

    complement component 5a receptor 1; C5R1, complement component 5 receptor 1 (C5a ligand); C5a anaphylatoxin chemotactic receptor; C5A; C5AR; CD88; C5a-R; C5a ligand; C5a anaphylatoxin receptor; complement component 5 receptor 1; C5R1

    		 Human HEK293
    C5AR1 Protein-VLP, Human (HEK293, His) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays.
  • HY-P702227
    C5AR2 Protein, Human (Cell-Free, His)

    C5a anaphylatoxin chemotactic receptor 2; Complement component 5a receptor 2; G-protein coupled receptor 77

    		 Human E. coli Cell-free
    The C5AR2 protein is a receptor for C3a, C4a, and C5a peptides as well as ASP/C3adesArg, C4adesArg, and C5adesArg, and is weakly coupled to G(i)-mediated signaling pathways. It interacts with C3 and exhibits higher affinity for the lipogenic hormone ASP. C5AR2 Protein, Human (Cell-Free, His) is the recombinant human-derived C5AR2 protein, expressed by E. coli Cell-free , with C-10*His labeled tag. The total length of C5AR2 Protein, Human (Cell-Free, His) is 337 a.a., with molecular weight of 38.9 kDa.
  • HY-P70882
    FAM172A Protein, Human (HEK293, His)

    Protein FAM172A; C5orf21

    		 Human HEK293
    The FAM172A protein has multiple uses in the regulation of alternative splicing, interacting with AGO2 and CHD7 to coordinate RNA processing and chromatin modification. In addition to its role in splicing, FAM172A stabilizes protein-protein interactions at the chromatin-spliceosome interface, revealing multifaceted functions. FAM172A Protein, Human (HEK293, His) is the recombinant human-derived FAM172A protein, expressed by HEK293 , with C-6*His labeled tag. The total length of FAM172A Protein, Human (HEK293, His) is 398 a.a., with molecular weight of 40-60 kDa.
  • HY-P71122
    NPR3 Protein, Human (HEK293, Fc)

    ANP-C; ANPR-C; NPR3; NPRC; NPR-C; ANPRC; C5orf23

    		 Human HEK293
    NPR3 Protein, a receptor for natriuretic peptides, exhibits similar affinities for NPPA/ANP, NPPB/BNP, and NPPC/CNP. It regulates diuresis, blood pressure, and skeletal development, possibly serving as a clearance receptor for NPPA, NPPB, and NPPC. Despite lacking guanylate cyclase activity, NPR3 forms disulfide-linked homodimers and interacts with OSTN, indicating potential involvement in various physiological processes. NPR3 Protein, Human (HEK293, Fc) is the recombinant human-derived NPR3 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of NPR3 Protein, Human (HEK293, Fc) is 458 a.a., with molecular weight of 90-100 kDa.
  • HY-P71394
    TXNDC15 Protein, Human (HEK293, His)

    Thioredoxin domain-containing protein 15; C5orf14; UNQ335/PRO534

    		Human HEK293
    TXNDC15 Protein positively regulates ciliary hedgehog signaling, crucial in cellular communication. It actively participates in ciliogenesis, contributing to the structural and functional dynamics of the cellular organelle. TXNDC15 Protein, Human (HEK293, His) is the recombinant human-derived TXNDC15 protein, expressed by HEK293, with C-6*His labeled tag. The total length of TXNDC15 Protein, Human (HEK293, His) is 289 a.a., with molecular weight of 50-60 kDa.
  • HY-P77430
    KCT2 Protein, Human (HEK293, His)

    Keratinocyte-associated transmembrane protein 2; KCT2; C5orf15; HTGN29

    		 Human HEK293
    KCT2 protein, widely expressed across diverse tissues and cell types, indicates potential involvement in various physiological processes, highlighting its ubiquity within the biological landscape. KCT2 Protein, Human (HEK293, His) is the recombinant human-derived KCT2 protein, expressed by HEK293 , with C-His labeled tag. The total length of KCT2 Protein, Human (HEK293, His) is 147 a.a., with molecular weight of 33-47 kDa.
  • HY-P71151
    LMAN2 Protein, Human (HEK293, His)

    Vesicular Integral-Membrane Protein VIP36; Glycoprotein GP36b; Lectin Mannose-Binding 2; Vesicular Integral-Membrane Protein 36; VIP36; LMAN2; C5orf8

    		 Human HEK293
    LMAN2 Protein, an intracellular lectin, interacts with N-acetyl-D-galactosamine and high-mannose type glycans. This protein is integral to the transport and sorting of glycoproteins with high mannose-type glycans within the early secretory pathway, contributing significantly to cellular processes. LMAN2 Protein, Human (HEK293, His) is the recombinant human-derived LMAN2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of LMAN2 Protein, Human (HEK293, His) is 278 a.a., with molecular weight of ~34.8 kDa.
  • HY-P71585
    KDM3B Protein, Human (Myc, His-SUMO)

    5qNCA; C5orf7; JHDM2B; JmjC domain containing histone demethylation protein 2B; JmjC domain-containing histone demethylation protein 2B; jmjd1b; Jumonji domain containing 1B; Jumonji domain containing protein 1B; Jumonji domain-containing protein 1B; KDM3B; KDM3B_HUMAN; KIAA1082; Lysine (K) specific demethylase 3B ; Lysine-specific demethylase 3B; NET22; Nuclear protein 5qNCA

    		 Human E. coli
    KDM3B protein is a histone demethylase that mainly targets "Lys-9" of histone H3, catalyzes demethylation and produces formaldehyde and succinic acid by-products. In addition to histone modifications, KDM3B has been implicated in tumor suppressor activity, indicating its importance in cellular processes, gene expression regulation, and epigenetic modifications. KDM3B Protein, Human (Myc, His-SUMO) is the recombinant human-derived KDM3B protein, expressed by E. coli , with C-Myc, N-SUMO, N-His labeled tag. The total length of KDM3B Protein, Human (Myc, His-SUMO) is 224 a.a., with molecular weight of ~45.6 kDa.
  • HY-P74374
    C2/Complement C2 Protein, Mouse (HEK293, His)

    Complement C2; C3/C5 convertase; C2

    		 Mouse HEK293
    Complement C2 is a component of the classical pathway of the complement system and is cleaved by activated factor C1, resulting in the formation of two distinct fragments: C2b and C2a. The subsequent serine protease activity of C2a is critical for its subsequent interaction with the complement factor C4b, leading to the formation of C3 or C5 convertase. C2/Complement C2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived C2/Complement C2 protein, expressed by HEK293 , with C-His labeled tag. The total length of C2/Complement C2 Protein, Mouse (HEK293, His) is 760 a.a., with molecular weight of ~91.2 kDa.
  • HY-P74375
    C2/Complement C2 Protein, Human (HEK293, His)

    Complement C2; C3/C5 convertase; C2

    		 Human HEK293
    C2/Complement C2 protein is essential in the classical pathway of the complement system. Activated by factor C1, C2 is cleaved into C2b and C2a. As a serine protease, C2a interacts with C4b, generating the C3 or C5 convertase. This crucial process activates and amplifies the complement cascade. C2/Complement C2 Protein, Human (HEK293, His) is the recombinant human-derived C2/Complement C2 protein, expressed by HEK293 , with C-His labeled tag. The total length of C2/Complement C2 Protein, Human (HEK293, His) is 732 a.a., with molecular weight of ~112 kDa.
  • HY-P74376
    C2/Complement C2 Protein, Human (HEK293, Fc)

    Complement C2; C3/C5 convertase; C2

    		 Human HEK293
    C2/Complement C2 protein is essential in the classical pathway of the complement system. Activated by factor C1, C2 is cleaved into C2b and C2a. As a serine protease, C2a interacts with C4b, generating the C3 or C5 convertase. This crucial process activates and amplifies the complement cascade. C2/Complement C2 Protein, Human (HEK293, Fc) is the recombinant human-derived C2/Complement C2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of C2/Complement C2 Protein, Human (HEK293, Fc) is 732 a.a., with molecular weight of 110-130 kDa.
  • HY-P75711
    DNMT2 Protein, Human (sf9, GST)

    tRNA (cytosine(38)-C(5))-methyltransferase; M.HsaIIP; PuMet; TRDMT1; DNMT2

    		 Human Sf9 insect cells
    The DNMT2 protein exhibits remarkable specificity by selectively methylating cytosine 38 within the anticodon loop of tRNA (Asp). This site-specific methylation is critical for epigenetic modification of transfer RNA, affecting its structure, stability, and functional interactions. DNMT2 Protein, Human (sf9, GST) is the recombinant human-derived DNMT2 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of DNMT2 Protein, Human (sf9, GST) is 391 a.a., with molecular weight of ~60 kDa.
  • HY-P700697
    C2/Complement C2 Protein, Cynomolgus (HEK293, His)

    Complement C2; C3/C5 convertase; C2; ARMD14; CO2

    		 Cynomolgus HEK293
    Complement C2 is a component of the classical pathway of the complement system and is cleaved by activated factor C1, resulting in the formation of two distinct fragments: C2b and C2a. The subsequent serine protease activity of C2a is critical for its subsequent interaction with the complement factor C4b, leading to the formation of C3 or C5 convertase. C2/Complement C2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived C2/Complement C2 protein, expressed by HEK293 , with C-His labeled tag. The total length of C2/Complement C2 Protein, Cynomolgus (HEK293, His) is 732 a.a., with molecular weight of 90-110 kDa.
  • HY-P72137
    CFB Protein, Mouse (His)
    1 Publications Verification

    Cfb; Bf; H2-BfComplement factor B; EC 3.4.21.47; C3/C5 convertase; Complement factor B Ba fragment; Complement factor B Bb fragment

    		 Mouse E. coli
    CFB is an important component of the alternative pathway of the complement system and is cleaved by factor D, producing two fragments: Ba and Bb. The Bb fragment is characterized as a serine protease and subsequently forms a complex with complement factor 3b, ultimately producing a C3 or C5 convertase. CFB Protein, Mouse (His) is the recombinant mouse-derived CFB protein, expressed by E. coli , with N-6*His labeled tag. The total length of CFB Protein, Mouse (His) is 739 a.a., with molecular weight of ~87 kDa.
  • HY-P7813
    Complement Factor B/CFB Protein, Human (HEK293, His)

    rHuComplement Factor B, His; Complement Factor B; C3/C5 Convertase; Glycine-Rich Beta Glycoprotein; GBG; PBF2; Properdin Factor B; CFB; BF; BFD

    		 Human HEK293

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