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C6

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Cat. No. Compare Product Name Species Source
  • HY-P74373
    C6/Complement component C6 Protein, Human (HEK293, His)

    Complement component C6; C6

    		 Human HEK293
    C6/Complement component C6 Protein is a part of the lytic membrane attack complex formed during complement activation, which has an indispensable role in innate and acquired immune responses by forming pores in the plasma membrane of target cells, as well as cancer immune surveillance. It is a component of the complement cascade which can be incorporated into the cell membrane and cause cell lysis. People with C6 deficiency are prone to bacterial infection. C6/Complement component C6 Protein, Human (HEK293, His) is the recombinant human-derived C6/Complement component C6 protein, expressed by HEK293 , with C-His labeled tag. The total length of C6/Complement component C6 Protein, Human (HEK293, His) is 934 a.a., with molecular weight of ~110 kDa.
  • HY-P71658
    OARD1 Protein, Human (Myc, His)

    C6orf130; CF130_HUMAN; Chromosome 6 open reading frame 130; dJ34B21.3; O acetyl ADP ribose deacetylase C6orf130; Uncharacterized protein C6orf130

    		 Human E. coli
    OARD1 is an ADP:ATP antiporter that regulates mitochondrial energy dynamics by shuttling ADP for ATP synthesis and exporting ATP. It induces mitochondrial thermogenesis, uncouples proton flux and regulates ATP production efficiency. OARD1 Protein, Human (Myc, His) is the recombinant human-derived OARD1 protein, expressed by E. coli , with N-His, C-Myc labeled tag. The total length of OARD1 Protein, Human (Myc, His) is 151 a.a., with molecular weight of ~24.3 kDa.
  • HY-P77683
    GFRAL Protein, Cynomolgus (HEK293, His-Avi)

    GFR alpha-like; GFRAL; GRAL; C6orf144

    		 Cynomolgus HEK293
    The GFRAL protein is a brainstem-restricted receptor for GDF15 that regulates food intake, energy expenditure, and body weight in response to metabolic and toxin-induced stress. GFRAL binds to its ligand GDF15, interacts with RET, and activates the MAPK and AKT signaling pathways. GFRAL Protein, Cynomolgus (HEK293, His-Avi) is the recombinant cynomolgus-derived GFRAL protein, expressed by HEK293 , with N-His, N-Avi labeled tag. The total length of GFRAL Protein, Cynomolgus (HEK293, His-Avi) is 332 a.a., with molecular weight of 50-70 kDa.
  • HY-P77947
    GFRAL Protein, Mouse (HEK293, His-Avi)

    GFR alpha-like; GFRAL; GRAL; C6orf144

    		 Mouse HEK293
    GFRAL protein, a brainstem-restricted receptor, regulates food intake, energy expenditure, and body weight in response to metabolic and toxin-induced stresses. It binds with GDF15, interacts with RET, and activates MAPK- and AKT- signaling pathways. GFRAL acts as a receptor for GDF15 and mediates cellular signaling through RET, requiring prior GDF15 binding. GFRAL Protein, Mouse (HEK293, His-Avi) is the recombinant mouse-derived GFRAL protein, expressed by HEK293 , with N-His, N-Avi labeled tag. The total length of GFRAL Protein, Mouse (HEK293, His-Avi) is 331 a.a., with molecular weight of 48-60 kDa.
  • HY-P78449
    GFRAL Protein, Human (HEK293, His-Avi)

    GFR alpha-like; GFRAL; GRAL; C6orf144

    		 Human HEK293
    GFRAL Protein, a brainstem-restricted receptor for GDF15, regulates food intake, energy expenditure, and body weight in response to metabolic and toxin-induced stresses. Binding to its ligand, GDF15, GFRAL interacts with RET, activating MAPK- and AKT-signaling pathways. Through its extracellular domain, the receptor forms complexes with GDF15 and RET, mediating cellular signaling when RET is engaged post GDF15 binding. This interaction sequence underscores GFRAL's role in modulating physiological responses to metabolic challenges. GFRAL Protein, Human (HEK293, His-Avi) is the recombinant human-derived GFRAL protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of GFRAL Protein, Human (HEK293, His-Avi) is 333 a.a., with molecular weight of 48-62 kDa.
  • HY-P700449
    GFRAL Protein, Mouse (HEK293, His-Myc)

    GFR alpha-like; GFRAL; GRAL; C6orf144

    		 Mouse HEK293
    GFRAL protein, a brainstem-restricted receptor, regulates food intake, energy expenditure, and body weight in response to metabolic and toxin-induced stresses. It binds with GDF15, interacts with RET, and activates MAPK- and AKT- signaling pathways. GFRAL acts as a receptor for GDF15 and mediates cellular signaling through RET, requiring prior GDF15 binding. GFRAL Protein, Mouse (HEK293, His-Myc) is the recombinant mouse-derived GFRAL protein, expressed by HEK293, with C-Myc, N-10*His labeled tag. The total length of GFRAL Protein, Mouse (HEK293, His-Myc) is 330 a.a., with molecular weight of 42.1 kDa.
  • HY-P78135
    GFRAL Protein, Human (Biotinylated, HEK293, His-Avi)

    GFR alpha-like; GFRAL; GRAL; C6orf144

    		 Human HEK293
    The GFRAL protein is a brainstem-restricted receptor for GDF15 that regulates food intake, energy expenditure, and body weight in response to metabolic and toxin-induced stress. GFRAL binds to its ligand GDF15, interacts with RET, and activates the MAPK and AKT signaling pathways. GFRAL Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived GFRAL protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of GFRAL Protein, Human (Biotinylated, HEK293, His-Avi) is 333 a.a., with molecular weight of 48-62 kDa.
  • HY-P700728
    GFRAL Protein, Mouse (Biotinylated, HEK293, His-Avi)

    GFR alpha-like; GFRAL; GRAL; C6orf144

    		 Mouse HEK293
    GFRAL protein, a brainstem-restricted receptor, regulates food intake, energy expenditure, and body weight in response to metabolic and toxin-induced stresses. It binds with GDF15, interacts with RET, and activates MAPK- and AKT- signaling pathways. GFRAL acts as a receptor for GDF15 and mediates cellular signaling through RET, requiring prior GDF15 binding. GFRAL Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived GFRAL protein, expressed by HEK293, with C-Avi, N-His labeled tag. The total length of GFRAL Protein, Mouse (Biotinylated, HEK293, His-Avi) is 331 a.a., with molecular weight of 48-60 kDa.
  • HY-P700997
    GFRAL Protein, Cynomolgus (Biotinylated, HEK293, His-Avi)

    GFR alpha-like; GFRAL; GRAL; C6orf144

    		 Cynomolgus HEK293
    The GFRAL protein is a brainstem-restricted receptor for GDF15 that regulates food intake, energy expenditure, and body weight in response to metabolic and toxin-induced stress. GFRAL binds to its ligand GDF15, interacts with RET, and activates the MAPK and AKT signaling pathways. GFRAL Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) is the recombinant cynomolgus-derived GFRAL protein, expressed by HEK293 , with C-Avi, N-His labeled tag. The total length of GFRAL Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) is 332 a.a., with molecular weight of 50-70 kDa.
  • HY-P7847
    CutA Protein, Human (His)

    rHuProtein CutA/CUTA, His; Protein CutA; Acetylcholinesterase-Associated Protein; Brain Acetylcholinesterase Putative Membrane Anchor; CUTA; ACHAP; C6orf82

    		 Human E. coli
    CUTA protein is a trimeric membrane anchor protein of AChE and a homolog of the bacterial divalent cation chelator CutA1 protein. CUTA protein also interacts with BACE1 and inhibits APP beta processing and Aβ production. CutA Protein, Human (His) is the recombinant human-derived CutA protein, expressed by E. coli , with C-6*His labeled tag. The total length of CutA Protein, Human (His) is 156 a.a., with molecular weight of ~17.0 kDa.
  • HY-P701021
    LY6G6F Protein, Human (HEK293, hFc)

    C6orf21; G6F; LY6G6D; NG32

    		 Human HEK293
    LY6G6F protein participates in signal transduction pathways involving GRB2 and GRB7. Forming homodimers and interacting with GRB2 and GRB7 in a phosphorylation-dependent manner, LY6G6F likely modulates signal transduction cascades, suggesting its involvement in intricate cellular signaling networks. LY6G6F Protein, Human (HEK293, hFc) is the recombinant human-derived LY6G6F protein, expressed by HEK293 , with C-hFc labeled tag. The total length of LY6G6F Protein, Human (HEK293, hFc) is 219 a.a., with molecular weight of 53-63 kDa.
  • HY-P76259
    CHST3 Protein, Mouse (HEK293, His)

    Carbohydrate sulfotransferase 3; Chondroitin 6-O-sulfotransferase 1; C6ST-1; GST-0

    		 Mouse HEK293
    The CHST3 protein utilizes PAPS to keyly catalyze the transfer of sulfate to position 6 of GalNAc in chondroitin, the major proteoglycan in cartilage. CHST3 also sulfonates Gal residues in keratan sulfate and sialic acid LacNAc oligosaccharides with less efficiency. CHST3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CHST3 protein, expressed by HEK293 , with N-His labeled tag. The total length of CHST3 Protein, Mouse (HEK293, His) is 434 a.a., with molecular weight of 55-75 KDa.
  • HY-P702207
    ADTRP Protein, Human (Cell-Free, His, Myc)

    Androgen-dependent TFPI-regulating protein; Fatty acid esters of hydroxy fatty acids hydrolase ADTRP; FAHFA hydrolase ADTRP; C6orf105

    		 Human E. coli Cell-free
    ADTRP protein exhibits specialized enzymatic activity, specifically hydrolyzing bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), with a notable preference for branched FAHFAs. This unique function distinguishes ADTRP, as it does not hydrolyze other major lipid classes. Moreover, ADTRP regulates endothelial cells, influencing TFPI expression and cell-associated anticoagulant activity, observed in in vitro settings. ADTRP Protein, Human (Cell-Free, His, Myc) is the recombinant human-derived ADTRP protein, expressed by E. coli Cell-free , with N-10*His, C-Myc labeled tag. The total length of ADTRP Protein, Human (Cell-Free, His, Myc) is 230 a.a., with molecular weight of 31.8 kDa.
  • HY-P76944
    GCAP1 Protein, Human (sf9)

    Guanylyl cyclase-activating protein 1; Guanylate cyclase activator 1A; C6orf131; GCAP; GUCA1; GUCA1A

    		 Human Sf9 insect cells
    GCAP1 Proteinas, a pivotal regulator in the visual system, modulates retinal guanylyl cyclase activity based on intracellular calcium concentrations. Under low calcium, GCAP1 stimulates retinal guanylyl cyclase for dark state recovery in rod photoreceptors. Elevated calcium inhibits guanylyl cyclase activity, a crucial aspect of rod photoreceptor phototransduction. Additionally, GCAP1 may contribute to light response and recovery in cone photoreceptors under bright light. The protein's homodimeric structure enhances its regulatory capabilities in the visual signaling pathway. GCAP1 Protein, Human (sf9) is the recombinant human-derived GCAP1 protein, expressed by Sf9 insect cells , with tag free. and with residual Gly-Pro in N-terminal (not related to functional changes) mutation. The total length of GCAP1 Protein, Human (sf9) is 201 a.a., with molecular weight of ~20 kDa.
  • HY-P702208
    ADTRP Protein, Human (Cell-Free, His, SUMO, Myc)

    Androgen-dependent TFPI-regulating protein; Fatty acid esters of hydroxy fatty acids hydrolase ADTRP; FAHFA hydrolase ADTRP; C6orf105

    		 Human E. coli Cell-free
    ADTRP protein exhibits specialized enzymatic activity, specifically hydrolyzing bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), with a notable preference for branched FAHFAs. This unique function distinguishes ADTRP, as it does not hydrolyze other major lipid classes. Moreover, ADTRP regulates endothelial cells, influencing TFPI expression and cell-associated anticoagulant activity, observed in in vitro settings. ADTRP Protein, Human (Cell-Free, His, SUMO, Myc) is the recombinant human-derived ADTRP protein, expressed by E. coli Cell-free , with N-10*His, C-Myc, N-SUMO labeled tag. The total length of ADTRP Protein, Human (Cell-Free, His, SUMO, Myc) is 230 a.a., with molecular weight of 46.8 kDa.
  • HY-P76945
    GCAP1 Protein, Human (sf9, His-GST)

    Guanylyl cyclase-activating protein 1; Guanylate cyclase activator 1A; C6orf131; GCAP; GUCA1; GUCA1A

    		 Human Sf9 insect cells
    The GCAP1 protein is a key regulator in the visual system, regulating retinal guanylyl cyclase activity in response to intracellular calcium concentration. Under low calcium conditions, GCAP1 stimulates retinal guanylyl cyclase to return rod photoreceptors to the dark state. GCAP1 Protein, Human (sf9, His-GST) is the recombinant human-derived GCAP1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of GCAP1 Protein, Human (sf9, His-GST) is 201 a.a., with molecular weight of ~42 kDa.
  • HY-P75784
    G6B Protein, Human (HEK293, Fc)

    Megakaryocyte and platelet inhibitory receptor G6b; Protein G6b; MPIG6B; C6orf25; G6B-B

    		 Human HEK293
    The G6B protein is an inhibitory receptor critical for hematopoietic lineage differentiation, megakaryocyte function, and platelet production. Its effects include inhibiting platelet aggregation and activation induced by agonists such as ADP and collagen-related peptides. G6B Protein, Human (HEK293, Fc) is the recombinant human-derived G6B protein, expressed by HEK293 , with C-hFc labeled tag. The total length of G6B Protein, Human (HEK293, Fc) is 146 a.a., with molecular weight of ~40.2 kDa.
  • HY-P75785
    G6B Protein, Human (HEK293, His)

    Megakaryocyte and platelet inhibitory receptor G6b; Protein G6b; MPIG6B; C6orf25; G6B-B

    		 Human HEK293
    The G6B protein is an inhibitory receptor critical for hematopoietic lineage differentiation, megakaryocyte function, and platelet production. Its effects include inhibiting platelet aggregation and activation induced by agonists such as ADP and collagen-related peptides. G6B Protein, Human (HEK293, His) is the recombinant human-derived G6B protein, expressed by HEK293 , with C-His labeled tag. The total length of G6B Protein, Human (HEK293, His) is 125 a.a., with molecular weight of ~18-23 kDa.
  • HY-P71580
    GFRAL Protein, Human (His-SUMO)

    bA360D14.1; C6orf144; GDNF family receptor alpha-like; Gfral; GFRAL_HUMAN; GRAL; IVFI9356; UNQ9356; UNQ9356/PRO34128

    		 Human E. coli
    The GFRAL protein is a brainstem-restricted receptor for GDF15 that regulates food intake, energy expenditure, and body weight in response to metabolic and toxin-induced stress. GFRAL binds to its ligand GDF15, interacts with RET, and activates the MAPK and AKT signaling pathways. GFRAL Protein, Human (His-SUMO) is the recombinant human-derived GFRAL protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of GFRAL Protein, Human (His-SUMO) is 333 a.a., with molecular weight of ~53.8 kDa.
  • HY-P72337
    cGAS Protein, Human (His)
    1 Publications Verification

    Cyclic GMP-AMP synthase; cGAMP synthase; h-cGAS; 2'3'-cGAMP synthase; Mab-21 domain-containing protein 1; MB21D1; C6orf150

    		 Human E. coli
    The cGAS protein is a nucleotidyl transferase that crucially mediates innate immunity by catalyzing the formation of 2',3'-cGAMP from ATP and GTP upon binding to double-stranded DNA (dsDNA). As a DNA sensor, cGAS detects exogenous and endogenous DNA, triggering STING1 activation and type I interferon production. cGAS Protein, Human (His) is the recombinant human-derived cGAS protein, expressed by E. coli , with C-6*His labeled tag. The total length of cGAS Protein, Human (His) is 522 a.a., with molecular weight of ~58.9 kDa.
  • HY-P71383
    TREML2 Protein, Human (HEK293, Fc)

    Trem-like transcript 2 protein; TLT2; Triggering receptor expressed on myeloid cells-like protein 2; TLT2; C6orf76;

    		Human HEK293
    TREML2 protein acts as a cell surface receptor, interacting with CD276 on T-cells to enhance T-cell activation and modulate immune responses, particularly in regulating T-cell activation during immune reactions. TREML2 Protein, Human (HEK293, Fc) is the recombinant human-derived TREML2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TREML2 Protein, Human (HEK293, Fc) is 250 a.a., with molecular weight of 80-110 kDa.
  • HY-P71597
    cGAS Protein, Human (His-SUMO)

    C6orf150; cGAMP synthase; cGAS; CGAS_HUMAN; cGMP Synthase; Chromosome 6 open reading frame 150; Cyclic GMP-AMP synthase; h-cGAS; Hypothetical protein LOC115004; Mab 21 domain containing 1; Mab-21 domain-containing protein 1; MB21D1; MGC131892; MGC142166; MGC142168; OTTHUMP00000016743; OTTHUMP00000039330; protein MB21D1; Uncharacterized protein C6orf150

    		 Human E. coli
    The cGAS protein is a nucleotidyl transferase that crucially mediates innate immunity by catalyzing the formation of 2',3'-cGAMP from ATP and GTP upon binding to double-stranded DNA (dsDNA). As a DNA sensor, cGAS detects exogenous and endogenous DNA, triggering STING1 activation and type I interferon production. cGAS Protein, Human (His-SUMO) is the recombinant human-derived cGAS protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of cGAS Protein, Human (His-SUMO) is 362 a.a., with molecular weight of ~58.3 kDa.
  • HY-P700473
    LY6G6D Protein, Macaca fascicularis (P. pastoris, His)

    Protein Ly6-D; Megakaryocyte-enhanced gene transcript 1 protein; G6D; NG25; LY6-D; MEGT1; C6orf23

    		 Cynomolgus P. pastoris
  • HY-P72107
    BRCC36 Protein, Human (His-SUMO)

    BRCA1-A complex subunit BRCC36; BRCA1/BRCA2 containing complex subunit 3; BRCA1/BRCA2 containing complex subunit 36; BRCA1/BRCA2-containing complex subunit 3; BRCA1/BRCA2-containing complex subunit 36; Brcc3; BRCC3_HUMAN; BRCC36; BRISC complex subunit BRCC36; C6.1A ; Chromosome X open reading frame 53; CXorf53; Lys-63-specific deubiquitinase BRCC36; OTTHUMP00000061450

    		 Human E. coli
    BRCC36 is a metalloprotease that selectively cleaves "Lys-63" linked polyubiquitin chains, especially histones H2A and H2AX in the BRCA1-A complex during the DNA damage response. As the catalytic subunit of the BRISC complex, it also targets “Lys-63”-linked ubiquitin in various substrates, affecting mitotic spindle assembly and interferon signaling. BRCC36 Protein, Human (His-SUMO) is the recombinant human-derived BRCC36 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of BRCC36 Protein, Human (His-SUMO) is 315 a.a., with molecular weight of ~51.9 kDa.
  • HY-P71684
    BCAP31 Protein, Human (GST)

    6C6 AG; 6C6 AG tumor associated antigen; B-cell receptor-associated protein 31; BA31; CDM; CDM protein; DXS1357E; MS950; p28; p28 Bap31; Protein CDM; RP23-329M9.5

    		 Human E. coli
    The BCAP31 protein acts as a chaperone and is one of the most abundant endoplasmic reticulum (ER) proteins. The BCAP31 protein also serves as a cargo receptor for transmembrane protein export. BCAP31 stimulates the translocation of NDUFS4 and NDUFB11 to mitochondria, interacts with BCL2, and may be involved in caspase-8-mediated apoptosis. BCAP31 Protein, Human (GST) is the recombinant human-derived BCAP31 protein, expressed by E. coli , with N-GST labeled tag. The total length of BCAP31 Protein, Human (GST) is 242 a.a., with molecular weight of ~54.5 kDa.
  • HY-P77508
    XTP3TPA Protein, Human (His)

    dCTP pyrophosphatase 1; dCTPase 1; RS21C6; DCTPP1; CDA03

    		 Human E. coli
    XTP3TPA protein crucially hydrolyzes deoxynucleoside triphosphates (dNTPs), particularly preferring dCTP and its analogs, like 5-iodo-dCTP and 5-methyl-dCTP. This selective hydrolysis, reflecting high efficiency, likely safeguards against the incorporation of genotoxic nucleotide analogs into DNA or RNA, contributing to genomic integrity and protecting cellular nucleotide pools. XTP3TPA Protein, Human (His) is the recombinant human-derived XTP3TPA protein, expressed by E. coli , with N-His labeled tag. The total length of XTP3TPA Protein, Human (His) is 170 a.a., with molecular weight of ~19 kDa.
  • HY-P70216B
    Legumain Protein, Mouse (HEK293, C-6His)

    rMuLegumain/Asparaginyl Endopeptidase, His; Legumain; Lgmn; Asparaginyl endopeptidase; Protease cysteine 1; Prsc1

    		 Mouse HEK293
    Legumain proteins can slowly cleave aspartyl bonds, especially under acidic conditions. Legumain Protein, Mouse (HEK293, C-6His) is the recombinant mouse-derived Legumain protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Legumain Protein, Mouse (HEK293, C-6His) is 418 a.a., with molecular weight of ~54.8 kDa.

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