Search Result

Results for "

CD33

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (1) Antibody-Drug Conjugates (ADCs) (1) Apoptosis (1) Drug-Linker Conjugates for ADC (1) Small Interfering RNA (siRNA) (1) Topoisomerase (1)
By Research Areas:	Cancer (5) Neurological Disease (2)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-144399

CD33 splicing modulator 1	Others	Neurological Disease
CD33 splicing modulator 1 (Compound 1) is a CD33 splicing modulator. CD33/Siglec 3 is a myeloid lineage cell surface receptor that is known to regulate microglia activity. CD33 splicing modulator 1 increases exon 2 skipping in cellular mRNA pools. CD33 splicing modulator 1 has the potential for the research of neurodegenerative disease including Alzheimer's disease .

HY-109539

Gemtuzumab ozogamicin	Antibody-Drug Conjugates (ADCs) Apoptosis	Cancer
Gemtuzumab ozogamicin is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin (IgG4) antibody directed against CD33 that is conjugated to the cytotoxic drug Calicheamicin (HY-19609). Calicheamicin is a cytotoxic antibiotic. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia (AML) .

HY-P99971

Gemtuzumab	ADC Antibody	Cancer
Gemtuzumab is a monoclonal IgG4-κ antibody targeting *CD33* antigen, which present on leukemic myeloblasts of acute myeloid leukemia (AML). Gemtuzumab can be used for synthesis of antibody-drug conjugate (ADC), Gemtuzumab ozogamicin (HY-109539). Gemtuzumab ozogamicin consists of a cytotoxic derivative of Calicheamicin (a cytotoxic antibiotic), and a monoclonal antibody. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia .

HY-144399A

CD33 splicing modulator 1 hydrochloride	Others	Neurological Disease
CD33 splicing modulator 1 (Compound 1) hydrochloride is a CD33 splicing modulator. CD33/Siglec 3 is a myeloid lineage cell surface receptor that is known to regulate microglia activity. CD33 splicing modulator 1 hydrochloride increases exon 2 skipping in cellular mRNA pools. CD33 splicing modulator 1 hydrochloride has the potential for the research of neurodegenerative disease including Alzheimer's disease .

HY-RS02235

CD33 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CD33 Human Pre-designed siRNA Set A contains three designed siRNAs for CD33 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CD33 Human Pre-designed siRNA Set A CD33 Human Pre-designed siRNA Set A

HY-160649

MC-Gly-Gly-Phe-Gly-GABA-Exatecan	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
MC-Gly-Gly-Phe-Gly-GABA-Exatecan is an agent linker conjugate for ADC, with an inhibitor for Topoisomerase Exatecan (HY-13631) with IC₅₀ of 22 μM. MC-Gly-Gly-Phe-Gly-GABA-Exatecan targets various antibodies, exhibits cytotoxic and antitumor efficacy in vitro and in vivo .

Cat. No.	Product Name	Target	Research Area

HY-P99329

Vadastuximab Anti-Human CD33 Recombinant Antibody	Inhibitory Antibodies	Cancer
Vadastuximab is a humanized monoclonal antibody targeting CD33. Vadastuximab can be used to synthesize an ADC compound, Vadastuximab talirine .

HY-P99971

Gemtuzumab	ADC Antibody	Cancer
Gemtuzumab is a monoclonal IgG4-κ antibody targeting *CD33* antigen, which present on leukemic myeloblasts of acute myeloid leukemia (AML). Gemtuzumab can be used for synthesis of antibody-drug conjugate (ADC), Gemtuzumab ozogamicin (HY-109539). Gemtuzumab ozogamicin consists of a cytotoxic derivative of Calicheamicin (a cytotoxic antibiotic), and a monoclonal antibody. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia .

HY-P99958

Vixtimotamab AMV-564; TandAb T564	Inhibitory Antibodies	Cancer
Vixtimotamab (AMV-564; TandAb T564) is a bispecific tetravalent tandem diabody (TandAb) that targets human *CD33* and human CD3 antigens. Vixtimotamab can be used for the research of acute myeloid leukemia (AML) .

Recombinant Proteins Recommended:

CD33

Species:	Human (22) Rhesus Macaque (2) Mouse (7) Cynomolgus (3)
Tag:	His (22) Tag Free (2) Avi (10) Myc (1) Fc (12) Flag (1)
Source:	HEK293 (34)

Cat. No.	Compare	Product Name	Species	Source

HY-P72021

	*Siglec-3/CD33* Protein, Human (HEK293, Fc-Myc)** Sialic acid-binding Ig-like lectin 3 Siglec-3; gp67; CD33; SIGLEC3	Human	HEK293
	Siglec-3/CD33 protein is a sialic acid-binding lectin that mediates cell-cell interactions and maintains immune cell quiescence. It prefers α-2,3- and α-2,6-linked glycans with sialic acid. Siglec-3/CD33 Protein, Human (HEK293, Fc-Myc) is the recombinant human-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-Myc, C-Fc labeled tag. The total length of Siglec-3/CD33 Protein, Human (HEK293, Fc-Myc) is 242 a.a., with molecular weight of ~92 kDa.

HY-P72473

	*Siglec-3/CD33* Protein, Mouse (G236R, HEK293, His)** Myeloid Cell Surface Antigen CD33; Sialic Acid-Binding Ig-Like Lectin 3; Siglec-3; gp67; CD33; SIGLEC3	Mouse	HEK293
	Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Mouse (G236R, HEK293, His) is the recombinant mouse-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Siglec-3/CD33 Protein, Mouse (G236R, HEK293, His) is 223 a.a., with molecular weight of 30-45 kDa.

HY-P72472

	*Siglec-3/CD33* Protein, Human (HEK293, Fc-His)** Myeloid Cell Surface Antigen CD33; Sialic Acid-Binding Ig-Like Lectin 3; Siglec-3; gp67; CD33; SIGLEC3	Human	HEK293
	Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Human (HEK293, Fc-His) is the recombinant human-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-hFc, C-6*His labeled tag. The total length of Siglec-3/CD33 Protein, Human (HEK293, Fc-His) is 242 a.a., with molecular weight of ~80 kDa.

HY-P701262

	*FITC-Labeled Siglec-3/CD33* Protein, Human (HEK293, Fc)** CD33; SIGLEC3; gp67	Human	HEK293
	Siglec-3/CD33 protein is a sialic acid-binding lectin that mediates cell-cell interactions and maintains immune cell quiescence. It prefers α-2,3- and α-2,6-linked glycans with sialic acid. FITC-Labeled Siglec-3/CD33 Protein, Human (HEK293, Fc) is the recombinant human-derived FITC-Labeled Siglec-3/CD33 protein, expressed by HEK293 , with Fc labeled tag. The total length of FITC-Labeled Siglec-3/CD33 Protein, Human (HEK293, Fc) is 242 a.a., with molecular weight of 70-90 kDa.

HY-P75652

	*Siglec-3/CD33* Protein, Cynomolgus/Rhesus Macaque (Biotinylated, HEK293, His)** Myeloid Cell Surface Antigen CD33; Siglec-3; gp67; CD33; SIGLEC3	Rhesus Macaque	HEK293
	Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Cynomolgus/Rhesus Macaque (Biotinylated, HEK293, His) is the recombinant Rhesus Macaque-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-3/CD33 Protein, Cynomolgus/Rhesus Macaque (Biotinylated, HEK293, His) is 248 a.a., with molecular weight of ~27.3 kDa.

HY-P75651

	*Siglec-3/CD33* Protein, Cynomolgus/Rhesus Macaque (HEK293, His)** Myeloid Cell Surface Antigen CD33; Siglec-3; gp67; CD33; SIGLEC3	Rhesus Macaque	HEK293
	Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-3/CD33 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is 233 a.a., with molecular weight of ~45.2 kDa.

HY-P77536

	*Siglec-3/CD33* Protein, Human (Biotinylated, HEK293, His)** Myeloid Cell Surface Antigen CD33; Siglec-3; gp67; CD33; SIGLEC3	Human	HEK293
	Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-3/CD33 Protein, Human (Biotinylated, HEK293, His) is 242 a.a., with molecular weight of ~28.2 KDa.

HY-P73644

	*Siglec-3/CD33* Protein, Human (HEK293, His)** Myeloid Cell Surface Antigen CD33; Siglec-3; gp67; CD33; SIGLEC3	Human	HEK293
	Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Human (HEK293, His) is the recombinant human-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-3/CD33 Protein, Human (HEK293, His) is 242 a.a., with molecular weight of 40-46 kDa.

HY-P73642

	*Siglec-3/CD33* Protein, Human (HEK293, hFc)** Myeloid Cell Surface Antigen CD33; Siglec-3; gp67; CD33; SIGLEC3	Human	HEK293
	Siglec-3/CD33 protein is a sialic acid-binding lectin that mediates cell-cell interactions and maintains immune cell quiescence. It prefers α-2,3- and α-2,6-linked glycans with sialic acid. Siglec-3/CD33 Protein, Human (HEK293, hFc) is the recombinant human-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Siglec-3/CD33 Protein, Human (HEK293, hFc) is 242 a.a., with molecular weight (glycosylation form) of 68-80 kDa.

HY-P73640

	*Siglec-3/CD33* Protein, Mouse (HEK293, Fc)** Myeloid Cell Surface Antigen CD33; Siglec-3; gp67; CD33; SIGLEC3	Mouse	HEK293
	Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Siglec-3/CD33 Protein, Mouse (HEK293, Fc) is 240 a.a., with molecular weight of 55-60 kDa.

HY-P73639

	*Siglec-3/CD33* Protein, Mouse (HEK293, His)** Myeloid Cell Surface Antigen CD33; Siglec-3; gp67; CD33; SIGLEC3	Mouse	HEK293
	Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-3/CD33 Protein, Mouse (HEK293, His) is 240 a.a., with molecular weight of 38-42 kDa.

HY-P73643

	*Siglec-3/CD33* Protein, Human (HEK293)** Myeloid Cell Surface Antigen CD33; Siglec-3; gp67; CD33; SIGLEC3	Human	HEK293
	Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Human (HEK293) is the recombinant human-derived Siglec-3/CD33 protein, expressed by HEK293 , with tag free. The total length of Siglec-3/CD33 Protein, Human (HEK293) is 242 a.a., with molecular weight of ~27.4 kDa.

HY-P73641

	*Siglec-3/CD33* Protein, Mouse (HEK293)** Myeloid Cell Surface Antigen CD33; Siglec-3; gp67; CD33; SIGLEC3	Mouse	HEK293
	Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Mouse (HEK293) is the recombinant mouse-derived Siglec-3/CD33 protein, expressed by HEK293 , with tag free. The total length of Siglec-3/CD33 Protein, Mouse (HEK293) is 240 a.a., with molecular weight of ~25.6 kDa.

HY-P78407

	*Siglec-3/CD33* Protein, Human (HEK293, His-Avi)** CD33 molecule; CD33; FLJ00391; gp67; Siglec3; Siglec-3; p67	Human	HEK293
	Siglec-3/CD33 protein is a sialic acid-binding lectin that mediates cell-cell interactions and maintains immune cell quiescence. It prefers α-2,3- and α-2,6-linked glycans with sialic acid. Siglec-3/CD33 Protein, Human (HEK293, His-Avi) is the recombinant human-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Siglec-3/CD33 Protein, Human (HEK293, His-Avi) is 242 a.a., with molecular weight of 52-60 kDa.

HY-P701037

	*Siglec-3/CD33* Protein, Human (Biotinylated, HEK293, His-Avi)** CD33 molecule; CD33; FLJ00391; gp67; Siglec3; Siglec-3; p67	Human	HEK293
	Siglec-3/CD33 protein, a sialic-acid-binding lectin, mediates cell-cell interactions and maintains immune cell quiescence. It prefers alpha-2,3- and more avidly alpha-2,6-linked sialic acid-bearing glycans. Upon ligand engagement, CD33's ITIMs phosphorylate, recruiting PTPN6/SHP-1 and PTPN11/SHP-2. These phosphatases, activated by Src-like kinases, regulate downstream pathways, including the repressive effect on monocyte activation through PI3K. CD33 also forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2, and engages C1QA via its C-terminus, activating inhibitory motifs. Siglec-3/CD33 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Siglec-3/CD33 protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of Siglec-3/CD33 Protein, Human (Biotinylated, HEK293, His-Avi) is 242 a.a., with molecular weight of 48-58 kDa.

HY-P78408

	*FITC-Labeled Siglec-3/CD33* Protein, Human (HEK293, His-Avi)** CD33 molecule; CD33; FLJ00391; gp67; Siglec3; Siglec-3; p67	Human	HEK293
	Siglec-3/CD33 protein is a sialic acid-binding lectin that mediates cell-cell interactions and maintains immune cell quiescence. It prefers α-2,3- and α-2,6-linked glycans with sialic acid. FITC-Labeled Siglec-3/CD33 Protein, Human (HEK293, His-Avi) is the recombinant human-derived FITC-Labeled Siglec-3/CD33 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of FITC-Labeled Siglec-3/CD33 Protein, Human (HEK293, His-Avi) is 242 a.a., with molecular weight of 48-58 kDa.

HY-P78208

	Siglec-15 Protein, Mouse (Biotinylated, HEK293, His) CD33 molecule-like 3; CD33L3; HsT1361; Siglec15; CD33 antigen-like 3; SIGLEC-15	Mouse	HEK293
	Siglec-15 Protein, a Siglec family member and type-1 transmembrane protein, is constitutively expressed in osteoclasts, macrophages and dendritic cells. Siglec-15 plays a pivotal role in the development and differentiation of osteoclastogenesis, inhibiting antigen-specific T cell responses in vitro and in vivo. Siglec-15 Protein, Mouse (Biotinylated, HEK293, His) is the recombinant mouse-derived Siglec-15 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-15 Protein, Mouse (Biotinylated, HEK293, His) is 239 a.a., with molecular weight of 35-43 kDa.

HY-P78353

	Siglec-15 Protein, Cynomolgus (HEK293, His-Avi) CD33 molecule-like 3; CD33L3; HsT1361; Siglec15; CD33 antigen-like 3; SIGLEC-15	Cynomolgus	HEK293
	Siglec-15 Protein, a Siglec family member and type-1 transmembrane protein, is constitutively expressed in osteoclasts, macrophages and dendritic cells. Siglec-15 plays a pivotal role in the development and differentiation of osteoclastogenesis, inhibiting antigen-specific T cell responses in vitro and in vivo. Siglec-15 Protein, Cynomolgus (HEK293, His-Avi) is the recombinant cynomolgus-derived Siglec-15 protein, expressed by HEK293 , with C-His, C-Avi labeled tag. The total length of Siglec-15 Protein, Cynomolgus (HEK293, His-Avi) is 244 a.a., with molecular weight of 33-43 kDa.

HY-P78515

	Siglec-15 Protein, Human (HEK293, His-Avi) CD33 molecule-like 3; CD33L3; HsT1361; Siglec15; CD33 antigen-like 3; SIGLEC-15	Human	HEK293
	Siglec-15 protein plays a crucial role in cellular interactions, selectively binding to sialylated glycoproteins with an affinity for sialic acid residues. Engaging with TYROBP and HCST, it indicates involvement in intricate signaling pathways. This specific recognition of sialylated glycoproteins underscores Siglec-15's significance in mediating immune responses and cellular communication, contributing to the complex network of cellular interactions. Siglec-15 Protein, Human (HEK293, His-Avi) is the recombinant human-derived Siglec-15 protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of Siglec-15 Protein, Human (HEK293, His-Avi) is 244 a.a., with molecular weight of 30-38 kDa.

HY-P701036

	Siglec-15 Protein, Cynomolgus (Biotinylated, 263a.a, HEK293, His-Avi) CD33 molecule-like 3; CD33L3; HsT1361; Siglec15; CD33 antigen-like 3; SIGLEC-15	Cynomolgus	HEK293
	The Siglec-15 protein plays a critical role in cellular interactions, selectively binding to sialylated glycoproteins with affinity for sialic acid residues. Binding to TYROBP and HCST suggests involvement in complex signaling pathways. Siglec-15 Protein, Cynomolgus (Biotinylated, 263a.a, HEK293, His-Avi) is the recombinant cynomolgus-derived Siglec-15 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Siglec-15 Protein, Cynomolgus (Biotinylated, 263a.a, HEK293, His-Avi) is 263 a.a., with molecular weight of 33-43 kDa.

HY-P70738

	Siglec-15 Protein, Human (HEK293, mFc) Sialic acid-binding Ig-like lectin 15; Siglec-15; CD33 antigen-like 3; CD33L3	Human	HEK293
	The Siglec-15 protein plays a critical role in cellular interactions, selectively binding to sialylated glycoproteins with affinity for sialic acid residues. Binding to TYROBP and HCST suggests involvement in complex signaling pathways. Siglec-15 Protein, Human (HEK293, mFc) is the recombinant human-derived Siglec-15 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of Siglec-15 Protein, Human (HEK293, mFc) is 244 a.a., with molecular weight of 50-70 kDa.

HY-P70742

	Siglec-15 Protein, Human (HEK293, Fc) Sialic acid-binding Ig-like lectin 15; Siglec-15; CD33 antigen-like 3; CD33L3	Human	HEK293
	The Siglec-15 protein plays a critical role in cellular interactions, selectively binding to sialylated glycoproteins with affinity for sialic acid residues. Binding to TYROBP and HCST suggests involvement in complex signaling pathways. Siglec-15 Protein, Human (HEK293, Fc) is the recombinant human-derived Siglec-15 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Siglec-15 Protein, Human (HEK293, Fc) is 244 a.a., with molecular weight of ~50-80 kDa.

HY-P70743

	Siglec-15 Protein, Cynomolgus (HEK293, His) Sialic acid-binding Ig-like lectin 15; Siglec-15; CD33 antigen-like 3; CD33L3	Cynomolgus	HEK293
	Siglec-15 Protein, a Siglec family member and type-1 transmembrane protein, is constitutively expressed in osteoclasts, macrophages and dendritic cells. Siglec-15 plays a pivotal role in the development and differentiation of osteoclastogenesis, inhibiting antigen-specific T cell responses in vitro and in vivo. Siglec-15 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Siglec-15 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Siglec-15 Protein, Cynomolgus (HEK293, His) is 244 a.a., with molecular weight of 30-40 kDa.

HY-P70744

	Siglec-15 Protein, Mouse (HEK293, His) Sialic acid-binding Ig-like lectin 15; Siglec-15; CD33 antigen-like 3; CD33L3	Mouse	HEK293
	Siglec-15 Protein, a Siglec family member and type-1 transmembrane protein, is constitutively expressed in osteoclasts, macrophages and dendritic cells. Siglec-15 plays a pivotal role in the development and differentiation of osteoclastogenesis, inhibiting antigen-specific T cell responses in vitro and in vivo. Siglec-15 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Siglec-15 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Siglec-15 Protein, Mouse (HEK293, His) is 239 a.a., with molecular weight of 30-40 kDa.

HY-P71031

	Siglec-6 Protein, Human (HEK293, Fc) CD327; CD33 antigen-like 1; CD33L1; CDw327; OB-BP1; Siglec6; Siglec-6	Human	HEK293
	Siglec-6 Protein, a putative adhesion molecule, facilitates sialic acid-dependent binding to cells, specifically binding to alpha-2,6-linked sialic acid. Its sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Siglec-6 interacts with LEP. Siglec-6 Protein, Human (HEK293, Fc) is the recombinant human-derived Siglec-6 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Siglec-6 Protein, Human (HEK293, Fc) is 305 a.a., with molecular weight of 70-90 kDa.

HY-P72475

	Siglec-15 Protein, Human (HEK293, His) Sialic acid-binding Ig-like lectin 15; Siglec-15; CD33 antigen-like 3; CD33L3	Human	HEK293
	The Siglec-15 protein plays a critical role in cellular interactions, selectively binding to sialylated glycoproteins with affinity for sialic acid residues. Binding to TYROBP and HCST suggests involvement in complex signaling pathways. Siglec-15 Protein, Human (HEK293, His) is the recombinant human-derived Siglec-15 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Siglec-15 Protein, Human (HEK293, His) is 244 a.a., with molecular weight of 30-40 kDa.

HY-P78354

	Siglec-5 Protein, Mouse (HEK293, His) CD170; CD33 antigen-like 2; CD33L2; OBBP2; Siglec5; SIGLEC5; OB-BP2	Mouse	HEK293
	Siglec-F Protein, a putative adhesion molecule, crucially mediates sialic-acid dependent binding to cells with a preferential affinity for alpha-2,3-linked sialic acid. Notably, its sialic acid recognition site may be concealed through cis interactions with sialic acids on the same cell surface. Siglec-5 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Siglec-5 protein, expressed by HEK293, with C-His labeled tag. The total length of Siglec-5 Protein, Mouse (HEK293, His) is 423 a.a., with molecular weight of 65-68 kDa.

HY-P700825

	Siglec-6 Protein, Human (HEK293, His-Avi) CD327; CD33 antigen-like 1; CD33L1; CDw327; OB-BP1; Siglec-6; SIGLEC6; CD33L; OBBP1	Human	HEK293
	Siglec-6 Protein, a putative adhesion molecule, facilitates sialic acid-dependent binding to cells, specifically binding to alpha-2,6-linked sialic acid. Its sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Siglec-6 interacts with LEP. Siglec-6 Protein, Human (HEK293, His-Avi) is the recombinant human-derived Siglec-6 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Siglec-6 Protein, Human (HEK293, His-Avi) is 305 a.a., with molecular weight of 55-70 kDa.

HY-P78203

	Siglec-5 Protein, Human (Biotinylated, HEK293, Fc) CD170; CD33 antigen-like 2; CD33L2; OBBP2; Siglec5; SIGLEC5; OB-BP2	Human	HEK293
	Siglec-5 Protein, a putative adhesion molecule, participates in sialic-acid dependent cellular binding, showing equal affinity for alpha-2,3-linked and alpha-2,6-linked sialic acid. Its sialic acid recognition site may be masked through cis interactions with sialic acids on the same cell surface. Siglec-5 Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived Siglec-5 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Siglec-5 Protein, Human (Biotinylated, HEK293, Fc) is 418 a.a., with molecular weight of 90-115 kDa.

HY-P701038

	Siglec-5 Protein, Human (HEK293, His-Avi) CD170; CD33 antigen-like 2; CD33L2; OBBP2; Siglec5; SIGLEC5; OB-BP2	Human	HEK293
	Siglec-5 Protein, a putative adhesion molecule, participates in sialic-acid dependent cellular binding, showing equal affinity for alpha-2,3-linked and alpha-2,6-linked sialic acid. Its sialic acid recognition site may be masked through cis interactions with sialic acids on the same cell surface. Siglec-5 Protein, Human (HEK293, His-Avi) is the recombinant human-derived Siglec-5 protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of Siglec-5 Protein, Human (HEK293, His-Avi) is 418 a.a., with molecular weight of 68-78 kDa.

HY-P70767

	Siglec-15 Protein, Human (Biotinylated, HEK293, Fc-Avi) Sialic acid-binding Ig-like lectin 15; Siglec-15; CD33 antigen-like 3; CD33L3	Human	HEK293
	The Siglec-15 protein plays a critical role in cellular interactions, selectively binding to sialylated glycoproteins with affinity for sialic acid residues. Binding to TYROBP and HCST suggests involvement in complex signaling pathways. Siglec-15 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived Siglec-15 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag. The total length of Siglec-15 Protein, Human (Biotinylated, HEK293, Fc-Avi) is 244 a.a., with molecular weight of 58-75 kDa.

HY-P701039

	Siglec-5 Protein, Human (Biotinylated, HEK293, His-Avi) CD170; CD33 antigen-like 2; CD33L2; OBBP2; Siglec5; SIGLEC5; OB-BP2	Human	HEK293
	Siglec-5 Protein, a putative adhesion molecule, participates in sialic-acid dependent cellular binding, showing equal affinity for alpha-2,3-linked and alpha-2,6-linked sialic acid. Its sialic acid recognition site may be masked through cis interactions with sialic acids on the same cell surface. Siglec-5 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Siglec-5 protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of Siglec-5 Protein, Human (Biotinylated, HEK293, His-Avi) is 418 a.a., with molecular weight of 70-80 kDa.

HY-P72471

	Siglec-5 Protein, Human (HEK293, Fc) Sialic acid-binding Ig-like lectin 5; Siglec-5; CD33 antigen-like 2; Obesity-binding protein 2; OB-BP2; CD170	Human	HEK293
	Siglec-5 Protein, a putative adhesion molecule, participates in sialic-acid dependent cellular binding, showing equal affinity for alpha-2,3-linked and alpha-2,6-linked sialic acid. Its sialic acid recognition site may be masked through cis interactions with sialic acids on the same cell surface. Siglec-5 Protein, Human (HEK293, Fc) is the recombinant human-derived Siglec-5 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Siglec-5 Protein, Human (HEK293, Fc) is 418 a.a., with molecular weight of 90-110 kDa.

HY-P71023

	Siglec-5 Protein, Human (HEK293, His-Flag-Fc) Sialic acid-binding Ig-like lectin 5; Siglec-5; CD33 antigen-like 2; Obesity-binding protein 2; OB-BP2; CD170	Human	HEK293
	Siglec-5 Protein, a putative adhesion molecule, participates in sialic-acid dependent cellular binding, showing equal affinity for alpha-2,3-linked and alpha-2,6-linked sialic acid. Its sialic acid recognition site may be masked through cis interactions with sialic acids on the same cell surface. Siglec-5 Protein, Human (HEK293, His-Flag-Fc) is the recombinant human-derived Siglec-5 protein, expressed by HEK293 , with C-hFc, C-Flag, C-6*His labeled tag. The total length of Siglec-5 Protein, Human (HEK293, His-Flag-Fc) is 418 a.a., with molecular weight of 90-110 kDa.

Cat. No.	Product Name	Application	Reactivity

HY-P81563

CD33 Antibody (YA1308)

Siglec-3
IHC-P Human

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