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Results for "

CD36 Inhibitors

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

3

Peptides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P5322
    Thrombospondin (TSP-1)-derived CD36 binding motif

    		Transmembrane Glycoprotein Cardiovascular Disease Cancer
    Thrombospondin (TSP-1)-derived CD36 binding motif is a bioactive hexapeptide. Thrombospondin (TSP-1)-derived CD36 binding motif interferes with the interaction between cells and the extracellular matrix by binding to CD36 and angiostatin, thereby affecting the cell adhesion and migration process. Thrombospondin (TSP-1)-derived CD36 binding motif inhibits platelet aggregation. Thrombospondin (TSP-1)-derived CD36 binding motif exerts an anti-tumor effect against colon cancer .
    Thrombospondin (TSP-1)-derived CD36 binding motif
  • HY-163541
    SMS121

    		Scavenger Receptor Class B type I (SR-BI） Cancer
    SMS121 is a CD36 inhibitor with a KD values of about 5 µM. SMS121 reduces the uptake of lipids and inhibits cell viability in acute myeloid leukemia cells. SMS121 has antitumor activity .
    SMS121
  • HY-112847A
    Sulfosuccinimidyl oleate sodium
    25+ Cited Publications

    Sulfo-N-succinimidyl oleate sodium

    		 Mitophagy Inflammation/Immunology
    Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate sodium is a potent and irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds the CD36 receptor on the surface of microglia. Anti-inflammatory effect .
    Sulfosuccinimidyl oleate sodium
  • HY-163649
    A17

    		AMPK Metabolic Disease
    A17 is a bile acid analog with anti-non-alcoholic steatohepatitis (NASH) and anti-inflammatory activities. A17 reduces fatty acid (FA) uptake and promotes FA oxidation though inhibiting fatty acid translocase (Cd36) expression and activating AMPKα. A17 can be used for NASH research .
    A17
  • HY-155938
    Cyano-myracrylamide

    		Acyltransferase Neurological Disease Inflammation/Immunology Cancer
    Cyano-myracrylamide is an inhibitor of zinc finger DHHC domain-containing palmitoyltransferase 20 (zDHHC20) with an IC50 value of 1.35 µM. Cyano-myracrylamide also inhibits the S-Acylation of EGFR and CD36. Cyano-myracrylamide also inhibits S-acylation of Legionella E3 ligase GobX, MyD88, and Ras, which are substrates of zDHHC20, zDHHC9, and zDHHC6, respectively, in HEK293T cells expressing recombinant Legionella GobX, recombinant human MyD88, or endogenous Ras .
    Cyano-myracrylamide
  • HY-P10183
    CD36 Peptide P (139-155), Cys conjugated

    Cys-CD36(139-155)

    		 Transmembrane Glycoprotein Inflammation/Immunology
    CD36 Peptide P (139-155), Cys conjugated is a Cys labelled CD36 Peptide, and can inhibit the immunoadsorption of CD36 by OKM5 .
    CD36 Peptide P (139-155), Cys conjugated
  • HY-112847
    Sulfosuccinimidyl oleate

    Sulfo-N-succinimidyl oleate

    		 Mitophagy Inflammation/Immunology
    Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate is a potent and irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate binds the CD36 receptor on the surface of microglia. Anti-inflammatory effect .
    Sulfosuccinimidyl oleate
  • HY-112847B
    (E/Z)-Sulfosuccinimidyl oleate sodium

    (E/Z)-Sulfo-N-succinimidyl oleate sodium

    		 Mitophagy Inflammation/Immunology
    (E/Z)-Sulfosuccinimidyl oleate sodium is a racemic compound of (Z)-Sulfosuccinimidyl oleate sodium and (Z)-Sulfosuccinimidyl oleate sodium isomers. Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate sodium is a potent and irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds the CD36 receptor on the surface of microglia. Sulfosuccinimidyl oleate sodium has anti-inflammatory effect .
    (E/Z)-Sulfosuccinimidyl oleate sodium
  • HY-168049
    ZLY06

    		PPAR Akt Metabolic Disease
    ZLY06 is an orally active dual agonist of peroxisome proliferator-activated receptor (PPAR) δ and γ (PPAR δ: EC50=341 nM; PPAR γ: EC50=237 nM). ZLY06 induces hepatic lipid accumulation by inhibiting the phosphorylation of AKT1, mediating the upregulation of CD36. In addition, ZLY06 significantly improves glucose and lipid metabolism without increasing body weight, and alleviates fatty liver by promoting β-oxidation of fatty acids and inhibiting hepatic lipogenesis .
    ZLY06
  • HY-P10873
    ST-CY14

    		Nuclear Hormone Receptor 4A/NR4A Mitochondrial Metabolism Cancer
    ST-CY14 is an inhibitor for Nur77-PPARγ interaction with an EC50 of 3.15 μM, that binds to Nur77 (Kd=32 nM), blocks Nur77 from being ubiquitinated and degraded by PPARγ, reduces fatty acid uptake and mitochondrial respiration, and inhibits the transcription of CD36 and FABP4. ST-CY14 inhibits the proliferation and migration of cancer cell MCF7 and MDA-MB-231. ST-CY14 inhibits tumor growth and bone metastasis in mouse models .
    ST-CY14

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