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Results for "

CD86

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Btk (1) Histone Demethylase (2) IFNAR (1) Small Interfering RNA (siRNA) (1) TNF Receptor (2) Toll-like Receptor (TLR) (5)
By Research Areas:	Cancer (4) Inflammation/Immunology (8)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-RS02274

CD86 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CD86 Human Pre-designed siRNA Set A contains three designed siRNAs for CD86 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CD86 Human Pre-designed siRNA Set A CD86 Human Pre-designed siRNA Set A

HY-152201

BTK-IN-18

Btk Cancer

BTK-IN-18 is a potent, reversible BTK inhibitor with an IC₅₀ of 0.002 µM. BTK-IN-18 inhibits both CD69 and CD86 in vivo .

BTK-IN-18	Btk	Cancer
BTK-IN-18 is a potent, reversible BTK inhibitor with an IC₅₀ of 0.002 µM. BTK-IN-18 inhibits both CD69 and CD86 in vivo .

HY-143410

Anti-inflammatory agent 16	TNF Receptor	Inflammation/Immunology
Anti-inflammatory agent 16 (compound 14), a peptidomimetic, shows potent anti-inflammatory activity. Anti-inflammatory agent 16 reduces TNFα, NO, CD40 and CD86 expression level .

HY-150740

ODN 21595	Toll-like Receptor (TLR)	Inflammation/Immunology
ODN 21595 is a Guanine-Modified TLR7 and TLR9 inhibitor. ODN 21595 inhibits the release of IFN-α and IL-6 with no cytotoxic. ODN 21595 reduces the expression of CD86 and HLA-DR. ODN 21595 has the potential for the research of systemic lupus erythematosus (SLE) .

HY-150740A

ODN 21595 sodium	Toll-like Receptor (TLR)	Inflammation/Immunology
ODN 21595 sodium is a Guanine-Modified TLR7 and TLR9 inhibitor. ODN 21595 sodium inhibits the release of IFN-α and IL-6 with no cytotoxic. ODN 21595 sodium reduces the expression of CD86 and HLA-DR. ODN 21595 sodium has the potential for the research of systemic lupus erythematosus (SLE) .

HY-144675

LSD1-IN-13	Histone Demethylase	Cancer
LSD1-IN-13 (compound 7e) is an orally active and potent LSD1 inhibitor, with an IC₅₀ of 24.43 nM. LSD1-IN-13 can activate CD86 expression, with an EC₅₀ of 470 nM. LSD1-IN-13 induces differentiation of AML (acute myeloid leukemia) cell lines .

HY-144675A

LSD1-IN-13 hydrochloride	Histone Demethylase	Cancer
LSD1-IN-13 hydrochloride (compound 7e) is an orally active and potent LSD1 inhibitor, with an IC₅₀ of 24.43 nM. LSD1-IN-13 hydrochloride can activate CD86 expression, with an EC₅₀ of 470 nM. LSD1-IN-13 hydrochloride induces differentiation of AML (acute myeloid leukemia) cell lines .

HY-150749

ODN D-SL03	IFNAR	Inflammation/Immunology Cancer
ODN D-SL03 is a C class CpG oligonucleotides, can induce stimulate PBMCs to produce high level of IFN-α. ODN D-SL03 can activate human B cells, NK cells and mononuclear cells and up-regulate expression of CD80, CD86 and HLA-DR on the surface of subsets in human PBMCs. ODN D-SL03 also can inhibit the growth of the tumor. ODN D-SL03 sequence: 5'-tcgcgaacgttcgccgcgttcgaacgcgg-3' .

HY-160227

ORN 06	Toll-like Receptor (TLR)	Inflammation/Immunology
ORN 06 (Compound R-0006), a U-rich single-stranded RNA (containing 6 repeats of the UUG sequence motif), is a TLR7/8 agonist. ORN 06 stimulates human TLR7/8-mediated or murine TLR7-mediated immunity .

HY-P99821

Ravagalimab

ABBV-323
TNF Receptor Inflammation/Immunology

Ravagalimab (ABBV-323) is a CD40 antagonist (EC₅₀: 3.7 nM). Ravagalimab can be used for research of Crohn's disease .

Ravagalimab ABBV-323	TNF Receptor	Inflammation/Immunology
Ravagalimab (ABBV-323) is a CD40 antagonist (EC₅₀: 3.7 nM). Ravagalimab can be used for research of Crohn's disease .

HY-148980

Polyinosinic acid	Toll-like Receptor (TLR)	Inflammation/Immunology
Polyinosinic acid is a single stranded homonucleic acid, which is a Toll-like Receptor 3 (TLR3) ligand. Polyinosinic acid enhances cellular immune response through TLR3 and TRIF. Polyinosinic acid has potential applications in immune regulation .

HY-148980A

Polyinosinic acid sodium	Toll-like Receptor (TLR)	Inflammation/Immunology
Polyinosinic acid sodium is the sodium form of Polyinosinic acid (HY-148980). Polyinosinic acid is a single stranded homonucleic acid, which is a Toll-like Receptor 3 (TLR3) ligand. Polyinosinic acid enhances cellular immune response through TLR3 and TRIF. Polyinosinic acid has potential applications in immune regulation .

Cat. No.	Product Name	Target	Research Area

HY-P990260

*Anti-Mouse CD86/B7-2 Antibody (GL-1)*	Inhibitory Antibodies	Others
Anti-Mouse CD86/B7-2 Antibody (GL-1) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse CD86/B7-2.

HY-P99821

Ravagalimab

ABBV-323
TNF Receptor Inflammation/Immunology

Ravagalimab (ABBV-323) is a CD40 antagonist (EC₅₀: 3.7 nM). Ravagalimab can be used for research of Crohn's disease .

Ravagalimab ABBV-323	TNF Receptor	Inflammation/Immunology
Ravagalimab (ABBV-323) is a CD40 antagonist (EC₅₀: 3.7 nM). Ravagalimab can be used for research of Crohn's disease .

Species:	Human (6) Rhesus Macaque (3) Rat (2) Mouse (2) Cynomolgus (4) Rabbit (1)
Tag:	His (12) Avi (2) Fc (4)
Source:	HEK293 (16)

Cat. No.	Compare	Product Name	Species	Source

HY-P7323

	*B7-2/CD86* Protein, Human (228a.a, HEK293, Fc-His)** rHuB7-2/CD86, Fc-His; Activation B7-2 antigen; B70; BU63; CD86; CD28LG2	Human	HEK293
	B7-2/CD86 Protein, Human (228a.a, HEK293, Fc-His) is a polypeptide chain with the C-termimal human Fc-His Tag produced in HEK293 cells. B7-2 (CD86) is a costimulatory molecule expressed by antigen-presenting cells (APCs), which interacts with CD28 for T-cell activation and survival and with CTLA4 for immune regulation.

HY-P7322

	*B7-2/CD86* Protein, Human (228a.a, HEK293, Fc)** rHuB7-2/CD86, Fc Chimera; Activation B7-2 antigen; B70; BU63; CD86; CD28LG2	Human	HEK293
	B7-2/CD86 Protein, Human (228a.a, HEK293, Fc) is a polypeptide chain with the C-termimal human IgG1 Fc fragment produced in HEK293 cells. B7-2 (CD86) is a costimulatory molecule expressed by antigen-presenting cells (APCs), which interacts with CD28 for T-cell activation and survival and with CTLA4 for immune regulation.

HY-P73492

	*B7-2/CD86* Protein, Rat (250a.a, HEK293, His)** Activation B7-2 antigen; B70; BU63; CD86; CD28LG2	Rat	HEK293
	B7-2/CD86 Protein is an immunoglobulin superfamily (IgSF) member with their extracellular regions consisting of one amino-terminal Ig variable-like (IgV) and one membrane proximal Ig constant-like (IgC) domain. CD86, a costimulatory ligand expressed on antigen-presenting cells (APC), binds the homologous T cell receptors CD28 and CTLA-4, and trigger costimulatory signals important for optimal T cell activation. CD86 is an immune checkpoint protein expressed on the surface of tumor cells and infiltrative tumor lymphocytes. B7-2/CD86 Protein, Rat (250a.a, HEK293, His) is the recombinant rat-derived B7-2/CD86 protein, expressed by HEK293 , with C-His labeled tag. The total length of B7-2/CD86 Protein, Rat (250a.a, HEK293, His) is 250 a.a., with molecular weight of 40-70 kDa.

HY-P75494

	*B7-2/CD86* Protein, Cynomolgus/Rhesus Macaque (HEK293, hFc)** Activation B7-2 antigen; B70; BU63; CD86; CD28LG2	Rhesus Macaque;Cynomolgus	HEK293
	B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Cynomolgus/Rhesus Macaque (HEK293, hFc) is the recombinant Rhesus Macaque, cynomolgus-derived B7-2/CD86 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of B7-2/CD86 Protein, Cynomolgus/Rhesus Macaque (HEK293, hFc) is 239 a.a., with molecular weight of ~76-86 & 34 kDa, respectively.

HY-P75493

	*B7-2/CD86* Protein, Cynomolgus/Rhesus Macaque (HEK293, His)** Activation B7-2 antigen; B70; BU63; CD86; CD28LG2	Rhesus Macaque;Cynomolgus	HEK293
	B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque, cynomolgus-derived B7-2/CD86 protein, expressed by HEK293 , with C-His labeled tag. The total length of B7-2/CD86 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is 239 a.a., with molecular weight of 54-66 kDa.

HY-P75489

	*B7-2/CD86* Protein, Human (Biotinylated, HEK293, His)** Activation B7-2 antigen; B70; BU63; CD86; CD28LG2	Human	HEK293
	B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived B7-2/CD86 protein, expressed by HEK293 , with C-His labeled tag. The total length of B7-2/CD86 Protein, Human (Biotinylated, HEK293, His) is 220 a.a., with molecular weight of ~26.2 kDa.

HY-P70795

	*B7-2/CD86* Protein, Human (224a.a, HEK293, His)** T-Lymphocyte Activation Antigen CD86; Activation B7-2 Antigen; B70; BU63; CTLA-4 Counter-Receptor B7.2; FUN-1; CD86; CD28LG2	Human	HEK293
	B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Human (224a.a, HEK293, His) is the recombinant human-derived B7-2/CD86 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of B7-2/CD86 Protein, Human (224a.a, HEK293, His) is 224 a.a., with molecular weight of 57-66 kDa.

HY-P7638

	*B7-2/CD86* Protein, Mouse (221a.a, HEK293, His)** rMuB7-2, His; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; Early T-cell costimulatory molecule 1; ETC-1; CD86	Mouse	HEK293
	B7-2/CD86 Protein, Mouse (HEK293, His), a second CTLA4 ligand expressed on murine B cells, can serve as a costimulatory molecule for T cell activation.

HY-P7835

	ILDR2/B7-2 Protein, Cynomolgus (HEK293, Fc) rCynIg-like domain-containing protein/B7-2, Fc; T-lymphocyte activation antigen CD86 isoform 1; Activation B7-2 antigen; CD86	Cynomolgus	HEK293
	The Ig-like domain of Ig-like domain-containing protein is a classic structure of tailed double-stranded (ds) DNA phage particles, which may be formed through weak interactions with carbohydrates on the surface of bacterial cells. Play an auxiliary role in phage infection. ILDR2/B7-2 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived ILDR2/B7-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ILDR2/B7-2 Protein, Cynomolgus (HEK293, Fc) is 222 a.a., with molecular weight of 90-120 kDa.

HY-P7637

	*B7-2/CD86* Protein, Rhesus macaque (217a.a, HEK293, His)** rRhB7-2, His; T-lymphocyte activation antigen CD86 isoform 1; Activation B7-2 antigen; CD86	Rhesus Macaque	HEK293
	B7-2 Protein, Rhesus macaque (HEK293, His), a second CTLA4 ligand expressed on murine B cells, can serve as a costimulatory molecule for T cell activation.

HY-P7635

	*B7-2/CD86* Protein, Mouse (HEK293, Fc)** rMuB7-2, C-Fc; T-lymphocyte activation antigen CD86; Early T-cell costimulatory molecule 1; ETC-1; CD86	Mouse	HEK293
	B7-2/CD86 Protein, Mouse (HEK293, Fc), a second CTLA4 ligand expressed on murine B cells, can serve as a costimulatory molecule for T cell activation.

HY-P7636

	*B7-2/CD86* Protein, Rat (219a.a, HEK293, His)** rRtB7-2, His; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CD86	Rat	HEK293
	B7-2/CD86 Protein, Rat (HEK293, His), a second CTLA4 ligand expressed on murine B cells, can serve as a costimulatory molecule for T cell activation.

HY-P72766

	*B7-2/CD86* Protein, Rabbit (HEK293, His)** T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CD86	Rabbit	HEK293
	The B7-2/CD86 protein is a key receptor that provides costimulatory signals critical for T lymphocyte proliferation and interleukin-2 production through CD28 or CTLA-4 binding. It plays a decisive role in early T cell activation, affecting immunity or anergy within 24 hours. B7-2/CD86 Protein, Rabbit (HEK293, His) is the recombinant Rabbit-derived B7-2/CD86 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of B7-2/CD86 Protein, Rabbit (HEK293, His) is 224 a.a., with molecular weight of 39-67 kDa.

HY-P78383

	*B7-2/CD86* Protein, Human (HEK293, His-Avi)** CD86 molecule; CD86; B70; B7-2 antigen; B72; B7-2; BU63; FUN-1; LAB72; MGC34413; CD28LG2	Human	HEK293
	B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Human (HEK293, His-Avi) is the recombinant human-derived B7-2/CD86 protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of B7-2/CD86 Protein, Human (HEK293, His-Avi) is 222 a.a., with molecular weight of 55-70 kDa.

HY-P78064

	*B7-2/CD86* Protein, Human (Biotinylated, HEK293, His-Avi)** CD86 molecule; CD86; B70; B7-2 antigen; B72; B7-2; BU63; FUN-1; LAB72; MGC34413; CD28LG2	Human	HEK293
	B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived B7-2/CD86 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of B7-2/CD86 Protein, Human (Biotinylated, HEK293, His-Avi) is 222 a.a., with molecular weight of 55-70 kDa.

HY-P78241

	*B7-2/CD86* Protein, Cynomolgus (215a.a, HEK293, His)** CD86 molecule; CD86; B70; B7-2 antigen; B72; B7-2; BU63; FUN-1; LAB72; MGC34413; CD28LG2	Cynomolgus	HEK293
	The Ig-like domain of Ig-like domain-containing protein is a classic structure of tailed double-stranded (ds) DNA phage particles, which may be formed through weak interactions with carbohydrates on the surface of bacterial cells. Play an auxiliary role in phage infection. B7-2/CD86 Protein, Cynomolgus (215a.a, HEK293, His) is the recombinant cynomolgus-derived B7-2/CD86 protein, expressed by HEK293 , with C-His labeled tag. The total length of B7-2/CD86 Protein, Cynomolgus (215a.a, HEK293, His) is 215 a.a., with molecular weight of 50-70 kDa.


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HY-P80609

CD86 Antibody CD86; CD28LG2; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD antigen CD86	WB, IHC-P, ICC/IF, IP, FC	Human, Rat
CD86 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 38 kDa, targeting to CD86. It can be used for WB,IHC-P,ICC/IF,IP,FC assays with tag free, in the background of Human, Rat.

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