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Results for "

COT

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Recombinant Proteins

Cat. No. Compare Product Name Species Source
  • HY-P75921

    Mitogen-activated protein kinase kinase kinase 8; TPL-2; MAP3K8; COT; ESTF

    Human Sf9 insect cells
    MAP3K8/TPL-2 is critical for LPS-induced, TLR4-mediated activation of MAPK/ERK, leading to TNF production by macrophages. It regulates T cell differentiation, IFNG expression, and host resistance to bacterial infections by negatively regulating type I interferon production. MAP3K8/TPL-2 Protein, Human (sf9, GST) is the recombinant human-derived MAP3K8/TPL-2 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of MAP3K8/TPL-2 Protein, Human (sf9, GST) is 368 a.a., with molecular weight of ~68 kDa.
  • HY-P74218

    Peroxisomal carnitine O-octanoyltransferase; CROT; COT

    Human Sf9 insect cells
    CROT Protein is pivotal in beta-oxidation, displaying highest enzymatic activity on C6 to C10 substrates. As a key player in lipid metabolism, CROT facilitates the conversion of 4,8-dimethylnonanoyl-CoA to its carnitine ester, regulating fatty acid oxidation for cellular energy balance. Understanding CROT's specific activities unveils mechanisms governing fatty acid catabolism, with potential implications for metabolic regulation and energy production. Further investigation into CROT's function holds promise for therapeutic interventions in metabolic disorders. CROT Protein, Human (V474L, sf9, His) is the recombinant human-derived CROT protein, expressed by Sf9 insect cells , with C-His labeled tag and V474L mutation. The total length of CROT Protein, Human (V474L, sf9, His) is 612 a.a., with molecular weight of ~65 kDa.

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