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Results for "

COX1/2

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

1

Fluorescent Dye

1

Biochemical Assay Reagents

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-115966
    COX-1/2-IN-1

    		COX Inflammation/Immunology
    COX-1/2-IN-2 is a potent COX1/2 inhibitor. COX-1/2-IN-2 exhibits significant inhibitory effect against COX-1 and COX-2 inhibitor with IC50 values of 13.9 ± 3.21 µM and 6.4±0.74 µM, respectively [1].
    <em>COX-1/2</em>-IN-1
  • HY-115967
    COX-1/2-IN-2

    		COX Inflammation/Immunology
    COX-1/2-IN-2 is a potent COX1/2 inhibitor. COX-1/2-IN-2 exhibits significant inhibitory effect against COX-1 and COX-2 inhibitor with IC50 values of 9.7 ± 0.09 µM and 4.6 ± 1.45 µM, respectively [1].
    <em>COX-1/2</em>-IN-2
  • HY-155768
    COX-1/2-IN-5

    		COX Cancer
    COX-1/2-IN-5 (compound 2a) is a dual inhibitor of COX1/2 (IC50=2.650 μM, 0.958 μM), with anticancer activity. COX-1/2-IN-5 inhibits liver cancer HepG2 with an IC50 of 60.75 μM [1].
    <em>COX-1/2</em>-IN-5
  • HY-162044
    COX-1/2-IN-6

    		COX Inflammation/Immunology
    COX-1/2-IN-6 (compound 4 h) is a potent dual inhibitor of COX-1 and COX-2 with IC50s of 68 and 91 nM, respectively. COX-1/2-IN-6 can used in study inflammation diseases [1].
    <em>COX-1/2</em>-IN-6
  • HY-147693
    COX-1/2-IN-3

    		COX Inflammation/Immunology
    COX-1/2-IN-3 (Compound 7a) is a COX-1 and COX-2 inhibitor. COX-2-IN-15 shows anti-inflammatory activity with low toxicity [1].
    <em>COX-1/2</em>-IN-3
  • HY-155764
    COX-1/2-IN-4

    		COX Cancer
    COX-1/2-IN-4 (compound 2b) is anCOX inhibitorwith IC50 values of 0.239 μM and 0.191 μM for COX-1 enzyme and COX-2 enzyme , respectively. COX-1/2-IN-4showsmoderateanticanceractivity against COLO205 and B16F1 cancer cell lines with IC50 values of 30.79 and 74.15 μM, respectively [1].
    <em>COX-1/2</em>-IN-4
  • HY-14397
    Indomethacin
    Maximum Cited Publications
    31 Publications Verification

    Indometacin

    		 COX Antibiotic Influenza Virus Bacterial Inflammation/Immunology Cancer
    Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research [1] .
    Indomethacin
  • HY-15034
    Indomethacin sodium

    Indometacin sodium

    		 COX Antibiotic Influenza Virus Bacterial Inflammation/Immunology Cancer
    Indomethacin (Indometacin) sodium is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium has anticancer activity and anti-infective activity. Indomethacin sodium can be used for cancer, inflammation and viral infection research. [1] .
    Indomethacin sodium
  • HY-14397A
    Indomethacin sodium hydrate
    Maximum Cited Publications
    31 Publications Verification

    Indometacin sodium hydrate

    		 COX Bacterial Influenza Virus Antibiotic Inflammation/Immunology Cancer
    Indomethacin (Indometacin) sodium hydrateis a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium hydrateis has anticancer activity and anti-infective activity. Indomethacin sodium hydrateis can be used for cancer, inflammation and viral infection research [1] .
    Indomethacin sodium hydrate
  • HY-153980
    K-80001

    		RAR/RXR COX Inflammation/Immunology
    K-80001 is an RXRα-binder and COX-1/2 inhibitor, with IC50s of with an IC50 of 82.9μM, 3.4μM, 1.2μM for RXRα, COX-1 and COX-2, respectively [1].
    K-80001
  • HY-14397G
    Indomethacin

    Indometacin

    		 Antibiotic Influenza Virus Bacterial COX Cancer
    Indomethacin (GMP) is Indomethacin (HY-14397) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research [1] .
    Indomethacin
  • HY-124481
    Oleocanthal

    		COX Inflammation/Immunology
    Oleocanthal is a COX-1/2 enzyme inhibitor and a nonsteroidal anti-inflammatory agent. Oleocanthal is obtained from virgin olive oil [1].
    Oleocanthal
  • HY-148224
    Pifoxime

    		COX Inflammation/Immunology
    Pifoxime is a COX-1/2 inhibitor, a non-steroidal anti-inflammatory agent (NSAID). Pifoxime shows anti-inflammatory activity, and can be used in neuropsychiatric research [1] .
    Pifoxime
  • HY-121585
    CAY10698

    		Lipoxygenase Inflammation/Immunology
    CAY10698 (compound 1) is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 5.1 μM. CAY10698 is inactive against 5-LOX, 15-LOX-1, 15-LOX-2 and COX-1/2 [1].
    CAY10698

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