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Results for "

CRHR1 Inhibitors

" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-124475

    CRFR Neurological Disease
    Antalarmin is a selective nonpeptide corticotropin-releasing factor receptor 1 (CRHR1) antagonist with a Ki of 2.7 nM. Antalarmin can pass through the blood–brain barrier.
  • HY-12131
    DMP 696

    CRFR Endocrinology Neurological Disease
    DMP 696 is a selective corticotropin-releasing hormone receptor 1 (CRHR1) antagonist, used for the treatment of anxiety and depression.
  • HY-103377
    Antalarmin hydrochloride

    CRFR Endocrinology Inflammation/Immunology
    Antalarmin (hydrochloride) is a non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist with a Ki of 1 nM. Antalarmin hydrochloride suppresses CRH-induced ACTH secretion and blocks CRH and novelty induced anxiety-like behavior in animal models. Antalarmin hydrochloride produces anti-inflammatory effects in arthritis models, and suppresses stress-induced gastric ulceration related to irritable bowel syndrome.