Search Result

Results for "

CSF

" in MedChemExpress (MCE) Product Catalog:

By Targets:	c-Fms (62) AP-1 (1) Apoptosis (4) Aurora Kinase (1) Autophagy (1) Bacterial (1) Beta-secretase (1) Biochemical Assay Reagents (1) c-Kit (9) c-Met/HGFR (1) COX (2) Fatty Acid Synthase (FASN) (1) FGFR (3) FLT3 (2) Fungal (1) Glutathione Peroxidase (1) HIF/HIF Prolyl-Hydroxylase (1) Interleukin Related (3) Liposome (1) MAP3K (1) Mitochondrial Metabolism (1) NF-κB (1) p38 MAPK (1) PDGFR (6) Raf (1) Ras (1) Reactive Oxygen Species (1) SARS-CoV (3) Small Interfering RNA (siRNA) (9) Src (3) STAT (1) TAM Receptor (2) VEGFR (6)
By Research Areas:	Cancer (51) Cardiovascular Disease (2) Infection (4) Inflammation/Immunology (33) Metabolic Disease (3) Neurological Disease (11)

By Targets:

c-Fms (62)

AP-1 (1)

Apoptosis (4)

Aurora Kinase (1)

Autophagy (1)

Bacterial (1)

Beta-secretase (1)

Biochemical Assay Reagents (1)

c-Kit (9)

c-Met/HGFR (1)

COX (2)

Fatty Acid Synthase (FASN) (1)

FGFR (3)

FLT3 (2)

Fungal (1)

Glutathione Peroxidase (1)

HIF/HIF Prolyl-Hydroxylase (1)

Interleukin Related (3)

Liposome (1)

MAP3K (1)

Mitochondrial Metabolism (1)

NF-κB (1)

p38 MAPK (1)

PDGFR (6)

Raf (1)

Ras (1)

Reactive Oxygen Species (1)

SARS-CoV (3)

Small Interfering RNA (siRNA) (9)

Src (3)

STAT (1)

TAM Receptor (2)

VEGFR (6)

By Research Areas:

Cancer (51)

Cardiovascular Disease (2)

Infection (4)

Inflammation/Immunology (33)

Metabolic Disease (3)

Neurological Disease (11)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

102

Recombinant Proteins

Antibodies

CSF1R-IN-20	c-Fms	Cancer
CSF1R-IN-20 (compound 7a) is a *CSF-1R* Inhibitor with an IC₅₀ value of 467 nM. CSF1R-IN-20 inhibits CSF-1R auto-phosphorylation .

CSF1R-IN-4	c-Fms	Cancer
CSF1R-IN-4 is a potent inhibitor of *CSF1R. CSF-1R is expressed in macrophages, and the survival and differentiation of macrophages depends on the CSF-1/CSF-1R signaling pathway. CSF1R-IN-4 affects the exchange of inflammatory factors between TAMs and glioma cells. CSF*1R-IN-4 has the potential for the research of cancer disease (extracted from patent WO2021197276A1, compound 104) .

CSF1R-IN-5	c-Fms	Cancer
CSF1R-IN-5 is a potent inhibitor of *CSF1R. CSF-1R is expressed in macrophages, and the survival and differentiation of macrophages depends on the CSF-1/CSF-1R signaling pathway. CSF1R-IN-5 affects the exchange of inflammatory factors between TAMs and glioma cells. CSF*1R-IN-5 has the potential for the research of cancer disease (extracted from patent WO2021197276A1, compound 11) .

CSF1R-IN-6	c-Fms	Cancer
CSF1R-IN-6 is a potent inhibitor of *CSF1R. CSF-1R is expressed in macrophages, and the survival and differentiation of macrophages depends on the CSF-1/CSF-1R signaling pathway. CSF1R-IN-6 affects the exchange of inflammatory factors between TAMs and glioma cells. CSF*1R-IN-6 has the potential for the research of cancer disease (extracted from patent WO2021197276A1, compound 5) .

CSF1R-IN-21	c-Fms	Neurological Disease
CSF1R-IN-21 (compound 7e) is a *CSF-1R* Inhibitor with an IC₅₀ value of 31 nM. CSF1R-IN-21 inhibits *CSF-1R* auto-phosphorylation and can be used for the research of neurodegenerative diseases .

CSF1R-IN-7	c-Fms	Neurological Disease
CSF1R-IN-7 (Formula I) is a *CSF-1R* inhibitor. CSF1R-IN-7 can be used for Alzheimer’s disease research .

CSF1R-IN-19	c-Fms	Cancer
CSF1R-IN-19 is a potent inhibitor of *CSF1R. CSF1R-IN-19 affects the exchange of inflammatory factors between TAMs and glioma cells. CSF*1R-IN-19 has the potential for the research of cancer .

CSF1R-IN-14	c-Fms	Cancer
CSF1R-IN-14 is an isoindolinone derivative compound. CSF1R-IN-14 is a potent inhibitor of *CSF1R. Colony stimulating factor 1 (CSF-1, also known as macrophage colony stimulating factor, M-CSF) is an important growth factor that controls bone marrow progenitor cells, monocytes, macrophages, and giants. CSF*1R-IN-14 has the potential for the research of cancer diseases (extracted from patent WO2019134662A1, compound 1) .

CSF1R-IN-10	c-Fms	Cancer
CSF1R-IN-10 (Compound 48) is a *CSF-1R* inhibitor with an IC₅₀ of 0.005 μM .

CSF1R-IN-8	c-Fms	Cancer
CSF1R-IN-8 (Compound 22) is a *CSF-1R* inhibitor with an IC₅₀ of 0.012 μM .

CSF1R-IN-9	c-Fms	Cancer
CSF1R-IN-9 (Compound 46) is a *CSF-1R* inhibitor with an IC₅₀ of 0.028 μM .

CSF1R-IN-17	c-Fms	Inflammation/Immunology
CSF1R-IN-17 (compound 9) is a potent and selective *CSF1R* antagonist, with an IC₅₀ of 0.2 nM. CSF1R-IN-17 can inhibit osteoclast differentiation .

CSF1R-IN-12	c-Fms	Cancer
CSF1R-IN-12 is a potent inhibitor of *CSF1R. Colony stimulating factor 1 (CSF-1, also known as macrophage colony stimulating factor, M-CSF) is an important growth factor that controls bone marrow progenitor cells, monocytes, macrophages, and giants. CSF*1R-IN-12 has the potential for the research of cancer diseases (extracted from patent WO2019134661A1, compound 1) .

CSF1R-IN-13	c-Fms	Cancer
CSF1R-IN-13 is a potent inhibitor of *CSF1R. Colony stimulating factor 1 (CSF-1, also known as macrophage colony stimulating factor, M-CSF) is an important growth factor that controls bone marrow progenitor cells, monocytes, macrophages, and giants. CSF*1R-IN-13 has the potential for the research of cancer diseases (extracted from patent WO2019134661A1, compound 32) .

CSF1R-IN-23	c-Fms	Neurological Disease Inflammation/Immunology
CSF1R-IN-23 (Compound 7dri) is a selective inhibitor for colony-stimulating factor-1 receptor (CSF1R), with IC₅₀ of 36.1 nM. CSF1R-IN-23 serves as antineuroinflammatory agent in mouse model. CSF1R-IN-23 is blood brain barrier (BBB) permeable .

CSF1R-IN-1	c-Fms	Cancer
CSF1R-IN-1 is a *CSF1R* inhibitor with an with an IC₅₀ of 0.5 nM.

CSF1R-IN-15	c-Fms	Others
CSF1R-IN-15 (compound 23) is an inhibitor targeting *CSF1R. The colony-stimulating factor-1 receptor (CSF1R) is a tyrosine kinase embedded in the cell membrane of macrophages. The receptor is activated by colony-stimulating factor-1 (CSF-1) and interleukin-34, and signaling via CSF*1R is crucial for the differentiation, proliferation, and survival of macrophages .

CSF1R-IN-3	c-Fms	Cancer
CSF1R-IN-3 (compound 21) is a potent and orally active *CSF-1R* inhibitor (IC₅₀=2.1 nM). CSF1R-IN-3 is a potent antiproliferative activity against colorectal cancer cells. CSF1R-IN-3 inhibits the progression of colorectal cancer by suppressing the migration of macrophages, reprograming M2-like macrophages to the M1 phenotype, and enhancing the antitumor immunity .

CSF1R-IN-18	c-Fms	Neurological Disease Cancer
CSF1R-IN-18 (Compdound 16t), para-aniline derivative, is a colony-stimulating factor 1 receptor (CSF1R) inhibitor. CSF1R-IN-18 can be used for the research of cancers, CNS-diseases and bone diseases .

CSF1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CSF1 Human Pre-designed siRNA Set A contains three designed siRNAs for CSF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CSF2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CSF2 Human Pre-designed siRNA Set A contains three designed siRNAs for CSF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CSF3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CSF3 Human Pre-designed siRNA Set A contains three designed siRNAs for CSF3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CSF1R Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CSF1R Human Pre-designed siRNA Set A contains three designed siRNAs for CSF1R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Csf1r Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Csf1r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Csf1r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Csf1r Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Csf1r Rat Pre-designed siRNA Set A contains three designed siRNAs for Csf1r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

CSF2RA Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CSF2RA Human Pre-designed siRNA Set A contains three designed siRNAs for CSF2RA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CSF2RB Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CSF2RB Human Pre-designed siRNA Set A contains three designed siRNAs for CSF2RB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CSF3R Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CSF3R Human Pre-designed siRNA Set A contains three designed siRNAs for CSF3R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Elzovantinib TPX-0022; CSF1R-IN-2	Src c-Met/HGFR c-Fms	Cancer
Elzovantinib (TPX-0022) is an oral-active inhibitor of SRC, MET and c-FMS, with IC₅₀ values of 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively .

*Axl/Mer/CSF1R-IN-2*	TAM Receptor c-Fms	Neurological Disease
Axl/Mer/CSF1R-IN-2 (Comp 4) is a Axl, Mer and *CSF1R* inhibitor .

*Anti-Mouse GM-CSF* Antibody (MP1-22E9)**	c-Fms	Inflammation/Immunology
Anti-Mouse GM-CSF Antibody is an anti-mouse GM-CSF IgG2a antibody inhibitor derived from host Rat.

Namilumab AMG-203; Anti-Human CSF2 Recombinant Antibody	c-Fms	Inflammation/Immunology
Namilumab (AMG203) is a human IgG1 monoclonal antibody that binds with high affinity to the *GM-CSF* ligand*, potently neutralizing GM-CSF*. Namilumab can be used for the research of rheumatoid arthritis .

*Axl/Mer/CSF1R-IN-1*	TAM Receptor c-Fms	Cancer
Axl/Mer-IN-1 (Compound 1) is an Axl/Mer receptor tyrosine kinase (Axl/Mer RTK) and *CSF1R* inhibitor with K_ds of <0.1 μM .

Atabecestat JNJ-54861911	Beta-secretase	Neurological Disease
Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction. Atabecestat s tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat has the potential for Alzheimer's Disease treatment .

Romurtide Muroctasin	Interleukin Related	Inflammation/Immunology
Romurtide (Muroctasin), a synthetic muramyl dipeptide derivative, is a cytokines inducer. Romurtide can increase peripheral neutrophils and monocytes in vivo and enhance production of colony-stimulating factors (CSFs), IL-1 and IL-6 in vitro .

Cabiralizumab FPA 008; Anti-Human CSF1R Recombinant Antibody	c-Fms	Inflammation/Immunology Cancer
Cabiralizumab (FPA 008) is an anti-CSF1R monoclonal antibody (MAb). Cabiralizumab enhances T cell infiltration and antitumor T cell immune responses. Cabiralizumab inhibits the activation of osteoclasts and blocks bone destruction, and can be used in the research of rheumatoid arthritis (RA). Cabiralizumab can combine with Nivolumab (HY-P9903) for lung cancer research .

Lacnotuzumab MCS110; Anti-Human B7-H3	c-Fms	Metabolic Disease Cancer
Lacnotuzumab (MCS110) is a neutralizing humanized IgG1/κ monoclonal antibody targeting *CSF-1* that prevents CSF-1 from activating the CSF-1R. Lacnotuzumab can be used for the research of pigmented villonodular synovitis .

cFMS Receptor Inhibitor II	c-Fms	Inflammation/Immunology
cFMS Receptor Inhibitor II is a *CSF1R* kinase inhibitor. CSF-1 is a cytokine .

Emactuzumab RG 7155; RO 5509554	c-Fms	Cancer
Emactuzumab(RG 7155) is a specific monoclonal antibody that inhibits colonystimulating factor 1 receptor *(CSF1R)* activation. Emactuzumab has high affinity for CSF-1R with K_i value of 0.2 nM to blocks CSF-1R dimerization. Emactuzumab can be used for the research of several diseases, such as diffuse-type tenosynovial giant cell tumour (dt-GCT) .

AZD7507 1 Publications Verification	c-Fms	Cancer
AZD7507 is a potent and orally active *CSF-1R* inhibitor, with antitumor activity.

Lenzilumab KB 003	SARS-CoV	Cancer
Lenzilumab (KB 003) is a human monoclonal antibody targeting *CSF2/GM-CSF* for COVID-19, chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML) studies .

Otilimab GSK 3196165; MOR103	c-Fms	Inflammation/Immunology
Otilimab (GSK 3196165) is an anti-granulocyte-macrophage colony-stimulating factor (GM-CSF) human monoclonal antibody. Otilimab neutralises the biological function of GM-CSF by blocking the interaction of GM-CSF with its cell surface receptor .

Mavrilimumab CAM 3001	c-Fms	Cardiovascular Disease Inflammation/Immunology
Mavrilimumab (CAM 3001) is a monoclonal antibody that binds to the α subunit of the granulocyte-macrophage colony stimulating factor (GM-CSF) receptor and blocks intracellular signalling downstream of GM-CSF. GM-CSF might be a mediator of the hyperactive inflammatory response associated with respiratory failure and death .

GENZ-882706 RA03546849	c-Fms	Inflammation/Immunology
GENZ-882706 is a potent colony stimulating factor-1 receptor (CSF-1R) Inhibitor extracted from patent WO 2017015267A1.

JTE-952	c-Fms	Inflammation/Immunology
JTE-952 is a potent, oral active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC₅₀ values of 13 nM and 261 nM for CSF1R and TrkA , respectively. Effective against a mouse collagen-induced model of arthritis .

c-Fms-IN-8	c-Fms	Cancer
c-Fms-IN-8 (compound 4a) is a *colony stimulating factor-1 receptor (CSF-1R, c-FMS)* Type II inhibitor, with an IC₅₀ of 9.1 nM .

Cat. No.	Product Name

HY-L161

Cytokine Inhibitors Library

811 Compounds compounds

Cytokines are a kind of low molecular soluble proteins synthesized and secreted by immunogen, mitogen or other factors. They have functions of regulating innate and adaptive immune responses, promoting hematopoiesis, stimulating cell activation, proliferation and differentiation. The process of releasing a large number of cytokines is also called “Cytokine storm”, which can cause damage to many tissues and organs in the body. Cytokine is involved in the pathogenesis of many human diseases, including cancer, diabetes, chronic inflammatory diseases and so on. Cytokine inhibitors are a class of essential compounds that act by directly inhibiting the synthesis and release of cytokine or blocking the binding of cytokine to their receptors. Cytokine inhibitors are important compounds for the study of tumor and autoimmune diseases.

MCE designs a unique collection of 811 cytokine inhibitors, mainly targeting the receptor interleukin (IL), colony-stimulating factor (CSF), interferon (IFN), tumor necrosis factor (TNF), growth factor (GF) and chemokine, which is an effective tool for development and research of anti-cancer, anti-chronic inflammatory diseases and anti-autoimmune diseases compounds.

Cat. No.	Product Name	Type

HY-139410

Sodium caseinates	Biochemical Assay Reagents
Sodium caseinates, the salt of casein, are the main milk protein. Sodium caseinate are able to induce proliferation and activation of granulocytes as well as increase the serum concentration of two key cytokines, GM-CSF and G-CSF. Sodium caseinate induces mouse granulopoiesis .

HY-151508

Diamino lipid DAL4	Drug Delivery
Diamino lipid DAL4 is diamino lipid for the preparation of lipid nanoparticles (LNPs) encapsulated with mRNAs encoding cytokines including IL-12, IL-27 and GM-CSF. Diamino lipid DAL4 delivers mRNA to tumor cells to exert anti-tumor activity .

Cat. No.	Product Name	Target	Research Area

HY-106228

HLF1-11	Fungal Bacterial Glutathione Peroxidase	Infection
HLF1-11, a human lactoferrin-derived peptide, is a broad spectrum antimicrobial agent. HLF1-11 inhibits human MPO activity. HLF1-11 also directs GM-CSF-driven monocyte differentiation toward macrophages, and enhances immune responses .

HY-122767

Romurtide Muroctasin	Interleukin Related	Inflammation/Immunology
Romurtide (Muroctasin), a synthetic muramyl dipeptide derivative, is a cytokines inducer. Romurtide can increase peripheral neutrophils and monocytes in vivo and enhance production of colony-stimulating factors (CSFs), IL-1 and IL-6 in vitro .

HY-P1111A

Lyn peptide inhibitor TFA	Src Interleukin Related	Inflammation/Immunology
Lyn peptide inhibitor TFA is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn peptide inhibitor TFA blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors. Lyn peptide inhibitor TFA can be used for study of asthma, allergic, and other eosinophilic disorders .

Cat. No.	Product Name	Target	Research Area

HY-P99134

Anti-Mouse GM-CSF Antibody (MP1-22E9)

c-Fms Inflammation/Immunology

Anti-Mouse GM-CSF Antibody is an anti-mouse GM-CSF IgG2a antibody inhibitor derived from host Rat.

HY-P99259

Cabiralizumab FPA 008; Anti-Human CSF1R Recombinant Antibody	c-Fms	Inflammation/Immunology Cancer
Cabiralizumab (FPA 008) is an anti-CSF1R monoclonal antibody (MAb). Cabiralizumab enhances T cell infiltration and antitumor T cell immune responses. Cabiralizumab inhibits the activation of osteoclasts and blocks bone destruction, and can be used in the research of rheumatoid arthritis (RA). Cabiralizumab can combine with Nivolumab (HY-P9903) for lung cancer research .

HY-P990257

Anti-Mouse CSF1 Antibody (5A1)

Inhibitory Antibodies Others

Anti-Mouse CSF1 Antibody (5A1) is a rat-derived IgG1, κ type antibody inhibitor, targeting to mouse CSF1.

HY-P99307

Namilumab AMG-203; Anti-Human CSF2 Recombinant Antibody	c-Fms	Inflammation/Immunology
Namilumab (AMG203) is a human IgG1 monoclonal antibody that binds with high affinity to the *GM-CSF* ligand*, potently neutralizing GM-CSF*. Namilumab can be used for the research of rheumatoid arthritis .

HY-P990125

*Anti-Mouse CSF1R (CD115) Antibody (AFS98)*	Inhibitory Antibodies	Others
Anti-Mouse CSF1R (CD115) Antibody (AFS98) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse CSF1R.

HY-P99368

Lacnotuzumab MCS110; Anti-Human B7-H3	c-Fms	Metabolic Disease Cancer
Lacnotuzumab (MCS110) is a neutralizing humanized IgG1/κ monoclonal antibody targeting *CSF-1* that prevents CSF-1 from activating the CSF-1R. Lacnotuzumab can be used for the research of pigmented villonodular synovitis .

HY-P99245

Emactuzumab RG 7155; RO 5509554	c-Fms	Cancer
Emactuzumab(RG 7155) is a specific monoclonal antibody that inhibits colonystimulating factor 1 receptor *(CSF1R)* activation. Emactuzumab has high affinity for CSF-1R with K_i value of 0.2 nM to blocks CSF-1R dimerization. Emactuzumab can be used for the research of several diseases, such as diffuse-type tenosynovial giant cell tumour (dt-GCT) .

HY-P99207

Lenzilumab KB 003	SARS-CoV	Cancer
Lenzilumab (KB 003) is a human monoclonal antibody targeting *CSF2/GM-CSF* for COVID-19, chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML) studies .

HY-P99795

Otilimab GSK 3196165; MOR103	c-Fms	Inflammation/Immunology
Otilimab (GSK 3196165) is an anti-granulocyte-macrophage colony-stimulating factor (GM-CSF) human monoclonal antibody. Otilimab neutralises the biological function of GM-CSF by blocking the interaction of GM-CSF with its cell surface receptor .

HY-P99031

Mavrilimumab CAM 3001	c-Fms	Cardiovascular Disease Inflammation/Immunology
Mavrilimumab (CAM 3001) is a monoclonal antibody that binds to the α subunit of the granulocyte-macrophage colony stimulating factor (GM-CSF) receptor and blocks intracellular signalling downstream of GM-CSF. GM-CSF might be a mediator of the hyperactive inflammatory response associated with respiratory failure and death .

HY-P99452

Axatilimab SNDX-6352	c-Fms	Inflammation/Immunology Cancer
Axatilimab (SNDX-6352) is a humanized IgG4 antibody with high affinity to *CSF-1R*. Axatilimab can be used for the research of chronic graft versus host disease (cGVHD) and neoplastic diseases .

HY-P99913

Eflapegrastim	c-Fms	Inflammation/Immunology
Eflapegrastim is a human IgG4 monoclonal antibody, is also a granulocyte colony-stimulating factor (G-CSF). Eflapegrastim targets to G-CSF receptor (c-Fms). Eflapegrastim stimulates proliferation and differentiation of neutrophil progenitor cells and maintains stable numbers of mature and functional neutrophils. Eflapegrastim also shortens the duration of neutropenia .

HY-P99879

Efbemalenograstim alfa Benegrastim; Bineuta; F 627	Inhibitory Antibodies	Inflammation/Immunology
Efbemalenograstim alfa (F 627) is a recombinant fusion protein. Efbemalenograstim alfa is a long acting dimeric granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2)-Fc fragment with a peptide linker. Efbemalenograstim alfa induces the production of white blood cells .

HY-P99779

Plonmarlimab TJ003234; TJM2	c-Fms SARS-CoV	Infection Inflammation/Immunology
Plonmarlimab (TJ003234) is an anti-GM-CSF monoclonal antibody. Plonmarlimab can be used for research of rheumatoid arthritis and COVID-19 .

HY-P99642

Gimsilumab MORAb-022	c-Fms SARS-CoV	Infection Inflammation/Immunology
Gimsilumab (MORAb-022) is a human anti-GM-CSF monoclonal antibody. Gimsilumab has the potential for the research of COVID-19 and rheumatoid arthritis (RA) .

HY-P99440

Anumigilimab CSL-324	c-Fms	Inflammation/Immunology
Anumigilimab (CSL-324) is an human IgG2a mAb against human *granulocyte colony-stimulating factor (G-CSF) receptor*. Anumigilimab can be used for increasing numbers of neutrophils at sites of inflammation .

HY-P99458

Balugrastim CG 10639	Inhibitory Antibodies	Cancer
Balugrastim (CG 10639) is a novel long-acting recombinant granulocyte colony-stimulating factor (G-CSF) obtained by means of a genetic fusion between recombinant human serum albumin and granulocyte colony-stimulating factor. Balugrastim can be used for the research of breast cancer .

HY-P9933

Dinutuximab Unituxin; APN-311	Inhibitory Antibodies	Cancer
Dinutuximab (Unituxin; APN-311) is a chimeric, human-murine, anti-GD2 monoclonal antibody. Dinutuximab potently enlongs event-free survival and overall survival, in high-risk neuroblastoma treatment, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), aldesleukin (interleukin-2 [IL-2]), and isotretinoin (13-cis-retinoic acid [RA]) .

HY-P990094

Trabikibart CSL311	Inhibitory Antibodies	Inflammation/Immunology
Trabikibart (CSL311), a βc-specific, fully human monoclonal antibody, binds to a unique epitope that is specific to the cytokine-binding site of the human βc receptor. Trabikibart has picomolar binding affinity for the human βc receptor. Trabikibart is a potent inhibitor of the combined effects of IL-3, GM-CSF and IL-5 on the survival of eosinophils. Trabikibart has the potential for chronic inflammatory diseases research .

Species:	Human (52) Porcine (1) Rhesus Macaque (6) Bovine (1) Mouse (23) Rat (9) Cynomolgus (8) Pig (1) Canine (2)
Tag:	His (54) Tag Free (32) Avi (6) Myc (1) GST (2) Fc (15) Flag (2)
Source:	HEK293 (61) CHO (9) P. pastoris (3) Sf9 insect cells (5) E. coli (24)

Cat. No.	Compare	Product Name	Species	Source

HY-P700512

	*GM-CSF* Protein, Bovine (P. pastoris, His-Myc)** colony stimulating factor 2 (granulocyte-macrophage); GMCSF; MGC131935; MGC138897; granulocyte-macrophage colony-stimulating factor; CSF; molgramostin; sargramostim; colony-stimulating factor; granulocyte-macrophage colony stimulating factor	Bovine	P. pastoris
	The GM-CSF protein is a key cytokine that fundamentally stimulates the growth and differentiation of hematopoietic precursor cells, including granulocytes, macrophages, eosinophils, and erythrocytes. As a monomer, GM-CSF interacts with the GM-CSF receptor complex to form a dodecamer, which contains two α, two β, and two head-to-head hexamers of the ligand subunits. GM-CSF Protein, Bovine (P. pastoris, His-Myc) is the recombinant bovine-derived GM-CSF protein, expressed by P. pastoris , with C-Myc, C-6*His labeled tag. The total length of GM-CSF Protein, Bovine (P. pastoris, His-Myc) is 126 a.a., with molecular weight of 18 kDa.

HY-P700180AF

	*Animal-Free GM-CSF* Protein, Mouse (His)** Granulocyte-Macrophage Colony-Stimulating Factor; GM-CSF; Colony-Stimulating Factor; CSF; Molgramostin; Sargramostim; CSF2; GMCSF	Mouse	E. coli
	GM-CSF Protein, a renowned cytokine, promotes the growth and differentiation of hematopoietic precursor cells, including granulocytes, macrophages, eosinophils, and erythrocytes. Operating as a monomer, it interacts with the GM-CSF receptor complex. This complex, comprising two head-to-head hexamers with two alpha, two beta, and two ligand subunits, forms a dodecamer structure. Animal-Free GM-CSF Protein, Mouse (His) is the recombinant mouse-derived animal-FreeGM-CSF protein, expressed by E. coli , with N-His labeled tag. The total length of Animal-Free GM-CSF Protein, Mouse (His) is 124 a.a., with molecular weight of ~15.1 kDa.

HY-P72629

	*GM-CSF* Protein, Rat (HEK293, His)** Granulocyte-Macrophage Colony-Stimulating Factor; GM-CSF; CSF; CSF2; GMCSF	Rat	HEK293
	GM-CSF Protein, a cytokine, promotes the growth and differentiation of hematopoietic precursor cells, including granulocytes, macrophages, eosinophils, and erythrocytes. It functions as a monomer, interacting with the GM-CSF receptor complex, forming a dodecamer structure with two alpha, two beta, and two ligand subunits in head-to-head hexamers (By similarity). GM-CSF Protein, Rat (HEK293, His) is the recombinant rat-derived GM-CSF protein, expressed by HEK293 , with C-6*His labeled tag. The total length of GM-CSF Protein, Rat (HEK293, His) is 127 a.a., with molecular weight of 17-25 kDa.

HY-P700508

	*GM-CSF* Protein, Human (P. pastoris, N-His)** colony stimulating factor 2 (granulocyte-macrophage); GMCSF; MGC131935; MGC138897; granulocyte-macrophage colony-stimulating factor; CSF; molgramostin; sargramostim; colony-stimulating factor; granulocyte-macrophage colony stimulating factor	Human	P. pastoris
	The GM-CSF protein functions as a key cytokine that promotes the growth and differentiation of hematopoietic precursor cells of different lineages, such as granulocytes, macrophages, eosinophils, and erythrocytes. In its monomeric form, GM-CSF acts as a signaling molecule, orchestrating complex receptor assemblies. GM-CSF Protein, Human (P. pastoris, N-His) is the recombinant human-derived GM-CSF protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of GM-CSF Protein, Human (P. pastoris, N-His) is 127 a.a., with molecular weight of 16.5 kDa.

HY-P73080

	*GM-CSF* Protein, Human (HEK293)** Granulocyte-macrophage colony-stimulating factor; GM-CSF; CSF; CSF-2	Human	HEK293
	The GM-CSF protein functions as a key cytokine that promotes the growth and differentiation of hematopoietic precursor cells of different lineages, such as granulocytes, macrophages, eosinophils, and erythrocytes. In its monomeric form, GM-CSF acts as a signaling molecule, orchestrating complex receptor assemblies. GM-CSF Protein, Human (HEK293) is the recombinant human-derived GM-CSF protein, expressed by HEK293 , with tag free. The total length of GM-CSF Protein, Human (HEK293) is 127 a.a., with molecular weight of ~19-25 kDa.

HY-P73082

	*GM-CSF* Protein, Mouse (HEK293, Fc)** Granulocyte-macrophage colony-stimulating factor; GM-CSF; CSF; CSF-2	Mouse	HEK293
	The GM-CSF protein acts as a potent cytokine that coordinates the growth and differentiation of hematopoietic precursor cells of different lineages, including granulocytes, macrophages, eosinophils, and erythrocytes. Structurally, GM-CSF exists as a monomer and its signaling is mediated through a dodecamer complex. GM-CSF Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived GM-CSF protein, expressed by HEK293 , with N-hFc labeled tag. The total length of GM-CSF Protein, Mouse (HEK293, Fc) is 124 a.a., with molecular weight of 45-60 kDa.

HY-P73081

	*GM-CSF* Protein, Human (HEK293, Fc)** Granulocyte-macrophage colony-stimulating factor; GM-CSF; CSF; CSF-2	Human	HEK293
	The GM-CSF protein functions as a key cytokine that promotes the growth and differentiation of hematopoietic precursor cells of different lineages, such as granulocytes, macrophages, eosinophils, and erythrocytes. In its monomeric form, GM-CSF acts as a signaling molecule, orchestrating complex receptor assemblies. GM-CSF Protein, Human (HEK293, Fc) is the recombinant human-derived GM-CSF protein, expressed by HEK293 , with N-hFc labeled tag. The total length of GM-CSF Protein, Human (HEK293, Fc) is 127 a.a., with molecular weight of 48-55 kDa.

HY-P70567

	*GM-CSF* Protein, Human (HEK293, His)** Granulocyte-macrophage colony-stimulating factor; Colony-stimulating factor; CSF; Molgramostin and Sargramostim.	Human	HEK293
	The GM-CSF protein functions as a key cytokine that promotes the growth and differentiation of hematopoietic precursor cells of different lineages, such as granulocytes, macrophages, eosinophils, and erythrocytes. In its monomeric form, GM-CSF acts as a signaling molecule, orchestrating complex receptor assemblies. GM-CSF Protein, Human (HEK293, His) is the recombinant human-derived GM-CSF protein, expressed by HEK293 , with C-6*His labeled tag. The total length of GM-CSF Protein, Human (HEK293, His) is 127 a.a., with molecular weight of 17-30 kDa.

HY-P70623

	*GM-CSF* Protein, Mouse (HEK293, His)** Granulocyte-Macrophage Colony-Stimulating Factor; GM-CSF; Colony-Stimulating Factor; CSF; Molgramostin; Sargramostim; CSF2; GMCSF	Mouse	HEK293
	The GM-CSF protein acts as a potent cytokine that coordinates the growth and differentiation of hematopoietic precursor cells of different lineages, including granulocytes, macrophages, eosinophils, and erythrocytes. Structurally, GM-CSF exists as a monomer and its signaling is mediated through a dodecamer complex. GM-CSF Protein, Mouse (HEK293, His) is the recombinant mouse-derived GM-CSF protein, expressed by HEK293 , with C-6*His labeled tag. The total length of GM-CSF Protein, Mouse (HEK293, His) is 124 a.a., with molecular weight of 18-30 kDa.

HY-P70567G

	*GMP GM-CSF* Protein, Human (HEK293, His)** Granulocyte-macrophage colony-stimulating factor; Colony-stimulating factor; CSF; Molgramostin and Sargramostim	Human	HEK293
	The GM-CSF protein functions as a key cytokine that promotes the growth and differentiation of hematopoietic precursor cells of different lineages, such as granulocytes, macrophages, eosinophils, and erythrocytes. In its monomeric form, GM-CSF acts as a signaling molecule, orchestrating complex receptor assemblies. GMP GM-CSF Protein, Human (HEK293, His) is the recombinant human-derived GM-CSF protein, expressed by HEK293 , with C-6*His labeled tag. The total length of GMP GM-CSF Protein, Human (HEK293, His) is 127 a.a., with molecular weight of 17-30 kDa.

HY-P7361

	*GM-CSF* Protein, Mouse** 4 Publications Verification rMuGM-CSF; CSF-2; GM-CSF	Mouse	E. coli
	GM-CSF Protein, Mouse is a member of colony-stimulating factors which regulates proliferation, differentiation, and survival of hematopoietic cells.

HY-P7386

	*M-CSF* Protein, Rat** rRtM-CSF; CSF-1; M-CSF	Rat	E. coli
	M-CSF Protein, Rat is a pro-inflammatory cytokine, binds to its receptor CSF1R, and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts which are important in the destruction of bone and cartilage and in the periarticular osteoporotic changes.

HY-P7361A

	*GM-CSF* Protein, Mouse (His)** 2 Publications Verification rMuGM-CSF; CSF-2; GM-CSF	Mouse	E. coli
	GM-CSF Protein, Mouse is a member of colony-stimulating factors which regulates proliferation, differentiation, and survival of hematopoietic cells.

HY-P7085

	*M-CSF* Protein, Mouse** Maximum Cited Publications 26 Publications Verification rMuM-CSF; CSF-1; MGI-IM	Mouse	E. coli
	M-CSF Protein, Mouse is a pro-inflammatory cytokine, binds to its receptor CSF1R, and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts which are important in the destruction of bone and cartilage and in the periarticular osteoporotic changes.

HY-P7050

	*M-CSF* Protein, Human** 4 Publications Verification rHuM-CSF; CSF-1; MGI-IM	Human	E. coli
	M-CSF Protein, Human is a hematopoietic growth factor with various glycosylation sites, affects survival and function of the tissue macrophages, and possesses antitumor activity.

HY-P7247

	*M-CSF* Protein, Rat (CHO)** 5+ Cited Publications rRtM-CSF; CSF1; MCSF	Rat	CHO
	M-CSF Protein, Rat (CHO) is a pro-inflammatory cytokine which binds to its receptor CSF1R, and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts.

HY-P7050A

	*M-CSF* Protein, Human (CHO)** 5 Publications Verification rHuM-CSF; CSF-1; MGI-IM	Human	CHO
	M-CSF Protein, Human (CHO) is a hematopoietic growth factor with various glycosylation sites, affects survival and function of the tissue macrophages, and possesses antitumor activity.

HY-P7085A

	*M-CSF* Protein, Mouse (CHO)** 4 Publications Verification rMuM-CSF; CSF-1; MGI-IM	Mouse	CHO
	M-CSF Protein, Mouse (CHO) is a pro-inflammatory cytokine, binds to its receptor CSF1R, and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts which are important in the destruction of bone and cartilage and in the periarticular osteoporotic changes.

HY-P700789

	*M-CSF* Protein, Cynomolgus (HEK293, His)** CSF1; CSF-1; MCSF; M-CSF; MGC31930; Lanimostim	Cynomolgus	HEK293
	The M-CSF protein regulates hematopoietic precursor cells, promoting their survival, proliferation, and differentiation. M-CSF Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived M-CSF protein, expressed by HEK293 , with C-His labeled tag. The total length of M-CSF Protein, Cynomolgus (HEK293, His) is 223 a.a., with molecular weight of 45-55 kDa.

HY-P78868

	*GM-CSF* Protein, Human (Tag Free)** 1 Publications Verification GM-CSF; CSF2; MGC131935	Human	HEK293
	The GM-CSF protein functions as a key cytokine that promotes the growth and differentiation of hematopoietic precursor cells of different lineages, such as granulocytes, macrophages, eosinophils, and erythrocytes. In its monomeric form, GM-CSF acts as a signaling molecule, orchestrating complex receptor assemblies. GM-CSF Protein, Human (Tag Free) is the recombinant human-derived GM-CSF protein, expressed by HEK293 , with tag free. The total length of GM-CSF Protein, Human (Tag Free) is 127 a.a., with molecular weight of 19-29 kDa.

HY-P78427

	*M-CSF* Protein, Human (HEK293, His-Avi)** CSF1; CSF-1; MCSF; M-CSF; MGC31930; Lanimostim	Human	HEK293
	The M-CSF protein is an important cytokine that modulates hematopoietic precursor cells, especially mononuclear phagocytes, affecting innate immunity and inflammation through the release of proinflammatory chemokines. It is essential for osteoclast proliferation and regulates bone resorption, bone development and fertility. M-CSF Protein, Human (HEK293, His-Avi) is the recombinant human-derived M-CSF protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of M-CSF Protein, Human (HEK293, His-Avi) is 158 a.a., with molecular weight of 28-34 kDa.

HY-P700222AF

	*Animal-Free M-CSF* Protein, Mouse (His)** rMuM-CSF; CSF-1; MGI-IM	Mouse	E. coli
	The M-CSF protein is a key orchestrator in regulating the survival, proliferation, and differentiation of hematopoietic precursor cells, particularly mononuclear phagocytes, including macrophages and monocytes. It actively promotes the release of pro-inflammatory chemokines, thereby playing a key role in innate immunity and inflammatory processes. Animal-Free M-CSF Protein, Mouse (His) is the recombinant mouse-derived animal-FreeM-CSF protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free M-CSF Protein, Mouse (His) is 155 a.a., with molecular weight of ~19.02 kDa.

HY-P701101

	*M-CSF* Protein, Human (CHO,Tag Free)** rHuM-CSF; CSF-1; MGI-IM	Human	CHO
	M-CSF Protein, Human (CHO) is a hematopoietic growth factor with various glycosylation sites, affects survival and function of the tissue macrophages, and possesses antitumor activity.

HY-P77909

	*GM-CSF* R alpha Protein, Mouse (HEK293, His)** GM-CSF-R-alpha; GMCSFR-alpha; GMR-alpha; CSF2R; CSF2RY; CSF2RA; CDw116; CD116; CSF2RAX; CSF2RAY; CSF2RX; GMCSFR; GMR; SMDP4	Mouse	HEK293
	GM-CSF R alpha is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2. GM-CSF R alpha binds to the cytokine with high specificity and low affinity. GM-CSF R alpha binds to GM-CSF and induces cell differentiation. GM-CSF R alpha monoclonal antibody decreases GM-CSFRα expression on GM-CSF-responsive cells and shows anti-inflammatory activity in rheumatoid arthritis (RA). GM-CSF R alpha Protein, Mouse (HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 298 amino acids (L30-P327) and is produced in HEK293 cells.

HY-P78110

	*GM-CSF* R alpha Protein, Human (Biotinylated, HEK293, His-Avi)** GM-CSF-R-alpha; GMCSFR-alpha; GMR-alpha; CSF2R; CSF2RY; CSF2RA; CDw116; CD116; CSF2RAX; CSF2RAY; CSF2RX; GMCSFR; GMR; SMDP4	Human	HEK293
	GM-CSF R alpha is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2. GM-CSF R alpha binds to the cytokine with high specificity and low affinity. GM-CSF R alpha binds to GM-CSF and induces cell differentiation. GM-CSF R alpha monoclonal antibody decreases GM-CSFRα expression on GM-CSF-responsive cells and shows anti-inflammatory activity in rheumatoid arthritis (RA). GM-CSF R alpha Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant protein with a C-Terminal His label and a C-Terminal Avi label, It consists of 298 amino acids (E23-G320) and is produced in HEK293 cells.

HY-P70493

	*M-CSF* Protein, Rat (HEK293)** Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; CSF1	Rat	HEK293
	The M-CSF protein regulates hematopoietic precursor cells, promoting their survival, proliferation, and differentiation. M-CSF Protein, Rat (HEK293) is the recombinant rat-derived M-CSF protein, expressed by HEK293 , with tag free. The total length of M-CSF Protein, Rat (HEK293) is 222 a.a., with molecular weight of ~46.0 kDa.

HY-P700788

	*M-CSF* Protein, Human (Biotinylated, HEK293, C-His-Avi)** CSF1; CSF-1; MCSF; M-CSF; MGC31930; Lanimostim	Human	HEK293
	The M-CSF protein is an important cytokine that modulates hematopoietic precursor cells, especially mononuclear phagocytes, affecting innate immunity and inflammation through the release of proinflammatory chemokines. It is essential for osteoclast proliferation and regulates bone resorption, bone development and fertility. M-CSF Protein, Human (Biotinylated, HEK293, C-His-Avi) is the recombinant human-derived M-CSF protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of M-CSF Protein, Human (Biotinylated, HEK293, C-His-Avi) is 158 a.a., with molecular weight of 27-37 kDa.

HY-P700730

	*GM-CSF* R alpha Protein, Cynomolgus (298.a.a, HEK293, His)** GM-CSF-R-alpha; GMCSFR-alpha; GMR-alpha; CSF2R; CSF2RY; CSF2RA; CDw116; CD116; CSF2RAX; CSF2RAY; CSF2RX; GMCSFR; GMR; SMDP4	Cynomolgus	HEK293
	GM-CSF R alpha Protein, a crucial type I cytokine receptor in the Type 5 subfamily, plays an essential role in mediating cellular responses to various cytokines. Sharing conserved features with related receptors, it transduces signals from specific type I cytokines, emphasizing its unique contributions to hematopoiesis and immune regulation within the broader context of cell signaling. Understanding GM-CSF R alpha's role holds promise for therapeutic interventions in hematopoietic disorders and immune dysregulation. GM-CSF R alpha Protein, Cynomolgus (298.a.a, HEK293, His) is the recombinant cynomolgus-derived GM-CSF R alpha protein, expressed by HEK293, with C-His labeled tag. The total length of GM-CSF R alpha Protein, Cynomolgus (298.a.a, HEK293, His) is 298 a.a., with molecular weight of 60-70 kDa.

HY-P79256

	*GM-CSF* Protein, Porcine** Granulocyte-macrophage colony-stimulating factor; CSF2; GM-CSF; Colony-stimulating factor; CSF; Granulocyte Macrophage Growth Factor	Porcine	E. coli
	The GM-CSF protein acts as a potent cytokine that coordinates the growth and differentiation of hematopoietic precursor cells of different lineages, including granulocytes, macrophages, eosinophils, and erythrocytes. Structurally, GM-CSF exists as a monomer and its signaling is mediated through a dodecamer complex. GM-CSF Protein, Porcine is the recombinant Porcine-derived GM-CSF protein, expressed by E. coli , with tag free. The total length of GM-CSF Protein, Porcine is 127 a.a., with molecular weight of ~17.02 kDa.

HY-P7015A

	*G-CSF* Protein, Human (CHO)** rHuG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim	Human	CHO
	G-CSF Protein, Human (CHO) is a polypeptide growth factor that regulates the production of neutrophilic granulocytes.

HY-P7068

	*G-CSF* Protein, Mouse (CHO)** rMuG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim	Mouse	CHO
	G-CSF Protein, Mouse (CHO) is a polypeptide growth factor that regulates the production of neutrophilic granulocytes.

HY-P7016A

	*GM-CSF* Protein, Human** 3 Publications Verification rHuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim	Human	E. coli
	GM-CSF Protein, Human is a hematopoietic growth factor and immune modulator.

HY-P7184

	*GM-CSF* Protein, Rhesus macaque** rRhGM-CSF; CSF2; Colony stimulating factor 2	Rhesus Macaque	E. coli
	GM-CSF Protein, Rhesus macaque functions as a cytokine and affects many cell types, especially macrophages and eosinophils.

HY-P70554

	*G-CSF* Protein, Mouse (HEK293, His)** Granulocyte colony-stimulating factor; CSF3; G-CSF	Mouse	HEK293
	The G-CSF Protein, a monomeric cytokine in the granulocyte/macrophage colony-stimulating factor family, crucially regulates hematopoiesis by orchestrating the production, differentiation, and function of granulocytes and monocytes-macrophages. Its production emphasizes its significance in maintaining immune system balance and functionality. G-CSF Protein, Mouse (HEK293, His) is the recombinant mouse-derived G-CSF protein, expressed by HEK293 , with C-6*His labeled tag. The total length of G-CSF Protein, Mouse (HEK293, His) is 178 a.a., with molecular weight of 25-27 kDa.

HY-P700137AF

	*Animal-Free M-CSF* Protein, Human (His)** Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; MCSF; Lanimostim; CSF1	Human	E. coli
	The M-CSF protein regulates macrophage production, differentiation, and function. It exists as an active disulfide-linked homodimer outside of cells, generated through proteolytic cleavage. It may also play a role in placental development. Alternative splicing produces multiple transcript variants. M-CSF is widely expressed in tissues such as placenta, spleen, and 25 other tissues. Animal-Free M-CSF Protein, Human (His) is the recombinant human-derived animal-FreeM-CSF protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free M-CSF Protein, Human (His) is 232 a.a., with molecular weight of ~13.34 kDa.

HY-P700239AF

	*Animal-Free GM-CSF* Protein, Pig (His)** CSF2	Pig	E. coli
	The GM-CSF protein acts as a potent cytokine that coordinates the growth and differentiation of hematopoietic precursor cells of different lineages, including granulocytes, macrophages, eosinophils, and erythrocytes. Structurally, GM-CSF exists as a monomer and its signaling is mediated through a dodecamer complex. Animal-Free GM-CSF Protein, Pig (His) is the recombinant pig-derived animal-FreeGM-CSF protein, expressed by E. coli , with N-His labeled tag. The total length of Animal-Free GM-CSF Protein, Pig (His) is 127 a.a., with molecular weight of ~15.3 kDa.

HY-P7069

	*GM-CSF* Protein, Mouse (CHO)** 1 Publications Verification rMuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim	Mouse	CHO
	GM-CSF Protein, Mouse (CHO) is a hematopoietic growth factor and immune modulator.

HY-P7093A

	*G-CSF* Protein, Rat (HEK293)** rRtG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim	Rat	HEK293
	G-CSF Protein, Rat (HEK293) is a glycoprotein, acting to stimulate granulopoiesis, the innate immunity, and the differentiation of neural progenitor cells.

HY-P7094

	*GM-CSF* Protein, Rat (CHO)** rRtGM-CSF; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim	Rat	CHO
	GM-CSF Protein, Rat (CHO) is a hematopoietic growth factor and immune modulator.

HY-P7016

	*GM-CSF* Protein, Human (CHO)** rHuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim	Human	CHO
	GM-CSF Protein, Human (CHO) is a hematopoietic growth factor and immune modulator.

HY-P700083AF

	*Animal-Free G-CSF* Protein, Human (His)** CSF-3; MGI-1G; GM-CSF beta; pluripoietin	Human	E. coli
	G-CSF, a pivotal cytokine, regulates hematopoiesis by controlling the production, differentiation, and function of granulocytes and monocytes-macrophages. This monomeric protein specifically promotes granulocyte development, playing a crucial role in immune system regulation and blood cell formation. Animal-Free G-CSF Protein, Human (His) is the recombinant human-derived animal-FreeG-CSF protein, expressed by E. coli , with N-His labeled tag. The total length of Animal-Free G-CSF Protein, Human (His) is 174 a.a., with molecular weight of ~19.48 kDa.

HY-P7016C

	*GM-CSF* Protein, Human (His)** rHuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim	Human	E. coli
	GM-CSF Protein, Human is a hematopoietic growth factor and immune modulator.

HY-P7015

	*G-CSF* Protein, Human (167a.a)** rHuG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim	Human	E. coli
	G-CSF Protein, Human (167a.a) is a polypeptide growth factor that regulates the production of neutrophilic granulocytes.

HY-P7016B

	*GM-CSF* Protein, Human (P.pastoris)** rHuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim	Human	P. pastoris
	GM-CSF Protein, Human (P.pastoris) is a hematopoietic growth factor and immune modulator.

HY-P700178AF

	*Animal-Free G-CSF* Protein, Mouse (His)** rMuG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim	Mouse	E. coli
	The G-CSF Protein, a monomeric cytokine in the granulocyte/macrophage colony-stimulating factor family, crucially regulates hematopoiesis by orchestrating the production, differentiation, and function of granulocytes and monocytes-macrophages. Its production emphasizes its significance in maintaining immune system balance and functionality. Animal-Free G-CSF Protein, Mouse (His) is the recombinant mouse-derived animal-FreeG-CSF protein, expressed by E. coli , with N-His labeled tag. The total length of Animal-Free G-CSF Protein, Mouse (His) is 178 a.a., with molecular weight of ~19.76 kDa.

HY-P70124

	CSF1R Protein, Cynomolgus (HEK293, His) rCynReceptor protein-tyrosine kinase/CSF1R, His; Macrophage colony-stimulating factor 1 receptor; CSF-1 receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD115; CSF1R; FMS	Cynomolgus	HEK293
	CSF1R is colony-stimulating factor receptor, a type I transmembrane protein receptor. Binding of CSF1R to CSF-1 or IL-34 activates a cascade of extracellular pro-cell survival kinases, including PI3K, ERK1/2, and JNK. CSF1R also recruits multiple downstream effector proteins/pathways, including PI3K, Grb2, SFK, Src, PKC, etc. CSF1R is involved in embryonic development and tissue repair and is associated with tumorigenesis and cancer progression. CSF1R Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CSF1R protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CSF1R Protein, Cynomolgus (HEK293, His) is 498 a.a., with molecular weight of 80-120 kDa.

HY-P700511

	CSF1R Protein, Human (HEK293, His-Flag) rCynReceptor protein-tyrosine kinase/CSF1R, His; Macrophage colony-stimulating factor 1 receptor; CSF-1 receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD115; CSF1R; FMS	Human	HEK293
	CSF1R protein is ubiquitously found in mononuclear phagocytes, especially macrophages and monocytes, and is involved in a variety of biological processes. It induces the release of proinflammatory chemokines in response to IL34 and CSF1, contributing to innate immunity and inflammation. CSF1R Protein, Human (HEK293, His-Flag) is the recombinant human-derived CSF1R protein, expressed by HEK293 , with C-6*His, C-Flag labeled tag. The total length of CSF1R Protein, Human (HEK293, His-Flag) is 493 a.a., with molecular weight of 57.7 kDa.

HY-P70488

	*M-CSF* Protein, Human (223a.a, HEK293, His)** 1 Publications Verification Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; MCSF; Lanimostim; CSF1	Human	HEK293
	The M-CSF protein is an important cytokine that modulates hematopoietic precursor cells, especially mononuclear phagocytes, affecting innate immunity and inflammation through the release of proinflammatory chemokines. It is essential for osteoclast proliferation and regulates bone resorption, bone development and fertility. M-CSF Protein, Human (223a.a, HEK293, His) is the recombinant human-derived M-CSF protein, expressed by HEK293 , with C-6*His labeled tag. The total length of M-CSF Protein, Human (223a.a, HEK293, His) is 223 a.a., with molecular weight of ~41.0 kDa.

HY-P700725

	G-CSFR/CD114 Protein, Mouse (HEK293, His) G-CSF-R; G-CSF R; CD114; G CSF R; CSF3R; CSFgr; GCSFR	Mouse	HEK293
	G-CSFR/CD114 Protein, functioning as the receptor for granulocyte colony-stimulating factor (CSF3), plays a pivotal role in granulocyte development and function. As a homodimer, it binds two CSF3 molecules, transducing signals. G-CSFR/CD114's interaction with CEACAM1 down-regulates the CSF3R-STAT3 pathway, recruiting PTPN6 for dephosphorylation, revealing regulatory roles in modulating granulocyte colony-stimulating factor responses. These interactions emphasize G-CSFR/CD114's intricate regulatory involvement in immune responses and hematopoiesis. G-CSFR/CD114 Protein, Mouse (HEK293, His) is the recombinant mouse-derived G-CSFR/CD114 protein, expressed by HEK293, with C-His labeled tag. The total length of G-CSFR/CD114 Protein, Mouse (HEK293, His) is 601 a.a., with molecular weight of 90-110 kDa.

HY-P73523

	*G-CSF* Protein, Human (HEK293)** Granulocyte Colony-Stimulating Factor; G-CSF; CSF3; C17orf33	Human	HEK293
	G-CSF, a pivotal cytokine, regulates hematopoiesis by controlling the production, differentiation, and function of granulocytes and monocytes-macrophages. This monomeric protein specifically promotes granulocyte development, playing a crucial role in immune system regulation and blood cell formation. G-CSF Protein, Human (HEK293) is the recombinant human-derived G-CSF protein, expressed by HEK293 , with tag free. The total length of G-CSF Protein, Human (HEK293) is 175 a.a., with molecular weight of ~17.8 kDa.

Cat. No.	Product Name	Application	Reactivity

HY-P83562

G-CSF Antibody (YA3307)

G-CSF; CSF beta; CSF3; CSF3OS; CSFg; Filgrastim; GCSA; GCSF; MGI 2; Pluripoietin
WB, ICC/IF, IP Human, Mouse, Rat

HY-P80750

*M-CSF* Antibody** CSF1; Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; Lanimostim	WB, IHC-F, IHC-P, ICC/IF	Human
M-CSF Antibody is a non-conjugated and Rabbit origined monoclonal antibody, targeting to M-CSF. It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human.

HY-P81554

CSF-1R Antibody (YA1299)

CSF-1R, M-CSF-R, CD115, CSF1R, FMS
IHC-P Human, Mouse
HY-P83460

M-CSF Receptor Antibody (YA3205)

M-CSF Receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD115
WB Human
HY-P83628

G-CSF Receptor Antibody (YA3373)

CSF3R; GCSFR; Granulocyte colony-stimulating factor receptor; G-CSF receptor; G-CSF-R; CD114
WB, FC Human
HY-P81444

CSF1R Antibody (YA1189)

CSF1R; FMS; Macrophage colony-stimulating factor 1 receptor; CSF-1 receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD antigen CD115
IHC-P Human
HY-P81686

CD114 Antibody (YA1431)

CSF3R; GCSFR; Granulocyte colony-stimulating factor receptor; G-CSF receptor; G-CSF-R; CD114
FC, ELISA Human

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