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Results for "

Chelating

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Amyloid-β (5) Antibiotic (2) Apoptosis (3) Autophagy (2) Bacterial (11) Biochemical Assay Reagents (21) Btk (1) Cholinesterase (ChE) (4) COX (1) Cuproptosis (2) DNA-PK (2) Dopamine β-hydroxylase (1) Drug Metabolite (1) Endogenous Metabolite (10) FAP (2) Ferroptosis (5) Fluorescent Dye (6) Fungal (3) GSK-3 (1) HCV (2) HDAC (1) Isotope-Labeled Compounds (5) Lipoxygenase (1) MCHR1 (GPR24) (2) Mitochondrial Metabolism (1) MMP (6) Monoamine Oxidase (4) NOD-like Receptor (NLR) (1) Oxidative Phosphorylation (1) Parasite (2) PSMA (3) Reactive Oxygen Species (2) Reverse Transcriptase (1) ROS Kinase (1) SOD (5) Xanthine Oxidase (2)
By Research Areas:	Cancer (35) Cardiovascular Disease (8) Endocrinology (2) Infection (13) Inflammation/Immunology (14) Metabolic Disease (5) Neurological Disease (25)
Click Chemistry:	Alkynes (1)

115

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y0569C

D-Gluconic acid potassium	Endogenous Metabolite Fungal	Infection Cancer
D-Gluconic acid potassium is an orally active carboxylic acid by the oxidation with antiseptic and chelating properties .

HY-114377

p-SCN-Bn-DOTA	Others	Cancer
p-SCN-Bn-DOTA is a bifunctional chelating agent. p-SCN-Bn-DOTA can simultaneously chelate radionuclides and link monoclonal antibody for radioimmunoresearch of tumor .

HY-W351339

BAPTA-TMFM

Fluorescent Dye Cancer

BAPTA-TMFM is a fluorescent chelating indicator used to study the role of cytosolic free calcium.
HY-155483

PSMA-BCH

NOTA-PSMA
Others Cancer

PSMA-BCH (NOTA-PSMA) is a NOTA-conjugated precursor. NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools .

BAPTA-TMFM	Fluorescent Dye	Cancer
BAPTA-TMFM is a fluorescent chelating indicator used to study the role of cytosolic free calcium.

PSMA-BCH NOTA-PSMA	Others	Cancer
PSMA-BCH (NOTA-PSMA) is a NOTA-conjugated precursor. NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools .

HY-W012037

8-Hydroxyquinoline hemisulfate 8-Quinolinol hemisulfate	Bacterial Antibiotic	Infection
8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.

HY-153551

HBED-CC-tris(tert-butyl ester)	Others	Others
HBED-CC-tris(tert-butyl ester), a HBED-CC derivative, is a bifunctional chelating agent. HBED-CC-tris(tert-butyl ester) is used in agricultural research and radiopharmacy .

HY-153551A

HBED-CC-tris(tert-butyl ester) TFA	Others	Others
HBED-CC-tris(tert-butyl ester) TFA, a HBED-CC derivative, is a bifunctional chelating agent. HBED-CC-tris(tert-butyl ester) is used in agricultural research and radiopharmacy .

HY-139975

Antitumor agent-31

Fluorescent Dye Cancer

Antitumor agent-31 is a nanosized chelates of anchoring bisazo dye. Antitumor agent-31 can be used for an antioxidant and antitumor agent .

Antitumor agent-31	Fluorescent Dye	Cancer
Antitumor agent-31 is a nanosized chelates of anchoring bisazo dye. Antitumor agent-31 can be used for an antioxidant and antitumor agent .

HY-129328

Magnesium glycinate 1 Publications Verification Magnesium bisglycinate; Magnesium diglycinate	Others	Cancer
Magnesium glycinate (Magnesium bisglycinate), the magnesium salt of glycine, is a nutrient supplement. Magnesium glycinate has satisfactory physico-chemical properties and bioactivities. Metal glycinate chelates are formed by glycine and metal compounds through chemical reactions. Magnesium is an essential mineral that plays a critical role in the human body. Magnesium takes part in the process of energy metabolism and assists the maintenance of normal muscle function .

HY-149820

MAO-B-IN-22	Monoamine Oxidase	Neurological Disease
MAO-B-IN-22 (compound 6h) is a potent MAO-B inhibitor with an IC₅₀ of 0.014 μM. MAO-B-IN-22 has high antioxidant activity, good metal chelating ability, proper BBB permeability and significant neuroprotective effect .

HY-121075

Alizarin complexone	Reverse Transcriptase	Infection
Alizarin complexone is a calcium-tracer and a chelating agent. Alizarin complexone is Rous-associated virus 2 reverse transcriptase (RAV-2 RT) inhibitor .

HY-N7059

Lactobionic acid	Bacterial	Infection
Lactobionic acid is a bionic acid naturally found in the Caspian Sea yogurt and chemically constituted of a gluconic acid bonded to a galactose. Lactobionic acid has antioxidant, antimicrobial, chelating, stabilizer, acidulant, and moisturizing properties .

HY-134418

NOTA	Others	Cancer
NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools. NOTA also can be used for probe design and signal amplification via the multivalent effect .

HY-W017457

DL-Penicillamine (±)-Penicillamine	Others	Others
DL-Penicillamine [(±)-Penicillamine] is a copper chelating agent. DL-Penicillamine has antidotal effects in thallotoxicosis rats when co-treated with Prussian blue (HY-106594A). DL-Penicillamine can cause pyridoxine deficiency and then induce optic axial neuritis. DL-Penicillamine can also depress primary immune response .

HY-W012683

Iminodiacetic acid	Others	Cancer
Iminodiacetic acid (IDA) is a chelating agent that strongly binds transition metals . Iminodiacetic acid can be used for removal of toxic metal ions from water . Iminodiacetic acid can serve as a biomarker to potentially predict the severity of ARDS (acute respiratory distress syndrome) .

HY-D0020

2,2'-Bipyridine	Biochemical Assay Reagents	Infection Endocrinology
2,2'-Bipyridine is the unique molecular scaffold of the bioactive natural products. 2,2'-Bipyridine is extensively used as the core structure of many chelating ligands by acting as a bridge in the arrangement of the catalytic center. 2,2'-Bipyridine shows robust redox stability and hyperglycemic activity .

HY-153552A

NH2-UAMC1110 TFA	FAP	Cancer
NH2-UAMC1110 TFA is a UAMC1110 derivative that can be used in the synthesis of FAPI-QS. UAMC1110 is a fibroblast activation protein (FAP) inhibitor. FAPI-QS is a chelating agent that can be used to synthesize high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors .

HY-N0420

Succinic acid 4 Publications Verification Wormwood acid	Endogenous Metabolite	Neurological Disease
Succinic acid is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid is an important platform chemical. Succinic acid can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .

HY-114091

PF-00356231 hydrochloride 1 Publications Verification	MMP	Inflammation/Immunology
PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC₅₀=1.4 μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC₅₀s of 0.00065, 1.7, 0.98, 0.39 μM, respectively .

HY-16564

Deferasirox (Fe3+ chelate)

Ferroptosis Bacterial Others

Deferasirox Fe3+ Chelate is an iron chelating agent extracted from patent WO2003053986 .

*Deferasirox (Fe3+ chelate)*	Ferroptosis Bacterial	Others
Deferasirox Fe3+ Chelate is an iron chelating agent extracted from patent WO2003053986 .

HY-W015410

Disodium succinate 4 Publications Verification	Endogenous Metabolite	Inflammation/Immunology
Disodium succinate is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Disodium succinate is an intermediate product of the tricarboxylic acid cycle. Disodium succinate is an important platform chemical. Disodium succinate can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .

HY-D1640

5',5-Difluoro BAPTA tetrapotassium	Biochemical Assay Reagents	Others
5,5'-Difluoro BAPTA tetrapotassium is a difluoro-derivative of BAPTA (HY-100168). 5,5'-Difluoro BAPTA tetrapotassium shows large ¹⁹F NMR chemical shifts upon chelating divalent cations. 5,5'-Difluoro BAPTA tetrapotassium has high selectivity for Ca ²⁺. 5,5'-Difluoro BAPTA tetrapotassium can inhibit the growth of pollen tube .

HY-150563

Neuroinflammatory-IN-2	Monoamine Oxidase Amyloid-β	Neurological Disease Inflammation/Immunology
Neuroinflammatory-IN-2 is a potent anti-neuroinflammatory agent with an IC₅₀ value of 10.30 μM for MAO-B, and 96.33% inhibition of Aβ_1-42 aggregation at 25 μM. Neuroinflammatory-IN-2 has neuroprotective activity in H₂O₂-induced PC-12 cell injury. Neuroinflammatory-IN-2 also has biometal chelating abilities, antioxidant activity, anti-neuroinflammatory activity and appropriate BBB permeability. Neuroinflammatory-IN-2 can be used for researching Alzheimer’s disease .

HY-Y0682

Ethylenediaminetetraacetic acid 5+ Cited Publications EDTA	Biochemical Assay Reagents Bacterial SOD	Cardiovascular Disease Neurological Disease
Ethylenediaminetetraacetic acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .

HY-W105700

Ethylenediaminetetraacetic acid sodium hydrate 5 Publications Verification EDTA sodium hydrate	Biochemical Assay Reagents Bacterial SOD	Cardiovascular Disease Neurological Disease
Ethylenediaminetetraacetic acid (EDTA) sodium hydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid sodium hydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid sodium hydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid sodium hydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid sodium hydrate can be used for coronary artery disease and neural system disease research .

HY-B1009

Ethylenediaminetetraacetic acid trisodium salt 5+ Cited Publications EDTA trisodium salt; Trisodium EDTA	Ferroptosis Bacterial SOD	Cardiovascular Disease Neurological Disease
Ethylenediaminetetraacetic acid trisodium salt (EDTA trisodium salt; Trisodium EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid trisodium salt has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid trisodium salt decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid trisodium salt can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .

HY-Y0682B

Ethylenediaminetetraacetic acid tetrasodium 5 Publications Verification EDTA tetrasodium	Biochemical Assay Reagents Bacterial SOD	Cardiovascular Disease Neurological Disease
Ethylenediaminetetraacetic acid (EDTA) tetrasodium is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid tetrasodium has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid tetrasodium decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid tetrasodium can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid tetrasodium can be used for coronary artery disease and neural system disease research .

HY-Y0682A

Ethylenediaminetetraacetic acid disodium dihydrate 5 Publications Verification EDTA disodium dihydrate	Biochemical Assay Reagents Bacterial SOD	Cardiovascular Disease Neurological Disease
Ethylenediaminetetraacetic acid (EDTA) disodium dehydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid disodium dehydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid disodium dehydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid disodium dehydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid disodium dehydrate can be used for coronary artery disease and neural system disease research .

HY-Y0569

D-Gluconic acid (solution)

D-Gluconic acid is the carboxylic acid by the oxidation with antiseptic and chelating properties.
HY-122107

Tropantiol

TRODAT-1
Others Others

Tropantiol (TRODAT-1) is a chelating agent .
HY-122107A

Tropantiol hydrochloride

TRODAT-1 hydrochloride
Others Others

Tropantiol (TRODAT-1) hydrochloride is a chelating agent .
HY-B1768

Succimer

Dimercaptosuccinic acid; DMSA
Others Others

Succimer is a widely used chelating agent for the treatment of Pb poisoning.
HY-W127819

Phenyleneethylenetriamine pentaacetic acid

Biochemical Assay Reagents Others

Phenyleneethylenetriamine Pentaacetic Acid is a precursor of a dual functional chelating agent .
HY-Y0569B

D-Gluconic acid calcium hydrate

Fungal Endogenous Metabolite Cancer

D-Gluconic acid calcium hydrate is the carboxylic acid by the oxidation with antiseptic and chelating properties.
HY-148646

p-NH2-CHX-A"-DTPA

Others Others

p-NH2-CHX-A"-DTPA is a bifunctional chelating agent .
HY-100332

CP 375

CP 375 is a Fe ³⁺ chelating agent, with a log K₁ value of 14.50.
HY-W342983

ATBTA-Eu3+

Fluorescent Dye Others

ATBTA-Eu3+ is a europium chelate that is fluorescent and can be used to label DNA .
HY-13950

S186

Others Others

S186 is a kind of sodium salts of calcium-acetylpropylamine phosphonate(APA); a new strontium-specific chelating agent.

D-Gluconic acid (solution)
D-Gluconic acid is the carboxylic acid by the oxidation with antiseptic and chelating properties.

Tropantiol TRODAT-1	Others	Others
Tropantiol (TRODAT-1) is a chelating agent .

Tropantiol hydrochloride TRODAT-1 hydrochloride	Others	Others
Tropantiol (TRODAT-1) hydrochloride is a chelating agent .

Succimer Dimercaptosuccinic acid; DMSA	Others	Others
Succimer is a widely used chelating agent for the treatment of Pb poisoning.

Phenyleneethylenetriamine pentaacetic acid	Biochemical Assay Reagents	Others
Phenyleneethylenetriamine Pentaacetic Acid is a precursor of a dual functional chelating agent .

D-Gluconic acid calcium hydrate	Fungal Endogenous Metabolite	Cancer
D-Gluconic acid calcium hydrate is the carboxylic acid by the oxidation with antiseptic and chelating properties.

p-NH2-CHX-A"-DTPA	Others	Others
p-NH2-CHX-A"-DTPA is a bifunctional chelating agent .

CP 375
CP 375 is a Fe ³⁺ chelating agent, with a log K₁ value of 14.50.

ATBTA-Eu3+	Fluorescent Dye	Others
ATBTA-Eu3+ is a europium chelate that is fluorescent and can be used to label DNA .

S186	Others	Others
S186 is a kind of sodium salts of calcium-acetylpropylamine phosphonate(APA); a new strontium-specific chelating agent.

HY-W030778

Nitrilotriacetic acid Triglycollamic acid	Others	Others
Nitrilotriacetic acid is an aminotricarboxylic acid. Nitrilotriacetic acid can be used as a chelating agent, forming coordination compounds with metal ions .

HY-W004650

TETA hydrochloride hydrate	Biochemical Assay Reagents	Others
TETA hydrochloride hydrate is an effective selective chelating agent for copper (II). TETA hydrochloride hydrate can be used for drug coupling .

HY-W102590

DOTMP	Biochemical Assay Reagents	Others
DOTMP is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-I0301

D-(+)-Glucono-1,5-lactone Gluconic acid lactone	Endogenous Metabolite Reactive Oxygen Species	Others
D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.

HY-114758

Pyridoxal isonicotinoyl hydrazone 2 Publications Verification PIH	Others	Cancer
Pyridoxal isonicotinoyl hydrazone (PIH) is a lipophilic, tridentate Fe-chelating agent that shows high Fe chelation efficacy .

HY-W749867

Ca(Ⅱ)-EDTA disodium dihydrate Calcium disodium EDTA dihydrate	Bacterial	Infection Others
CaⅡ-EDTA disodium dihydrate (Calcium disodium EDTA dihydrate) is an orally active metal chelating reagent, exhibits bactericidal activities against periodontal pathogens Aggregatibacter actinomycetemcomitans, Prevotella intermedia and Porphyromonas gingivalis . CaⅡ-EDTA disodium dihydrate is effective chelating antidotes for lead- and cadmium poisoning .

HY-W007656

Cyclen	Others	Others
Cyclen is the aza analogue of crown ether, used as a precursor for MRI contrast agents, and is an intermediate for the preparation of effective macrocyclic chelates .

HY-Y0308E

Sodium phosphate dibasic, for cell culture Disodium hydrogen phosphate, for cell culture	Biochemical Assay Reagents	Others
Sodium phosphate dibasic (Disodium hydrogen phosphate), for cell culture can be used as an excipient, such as buffer, chelating agent, can used for cell culture .

HY-W134005

Mg(Ⅱ)-EDTA disodium tetrahydrate Ethylenediaminetetraacetic acid magnesium disodium tetrahydrate	Biochemical Assay Reagents	Others
Mg(II)-EDTA (disodium tetrahydrate) is an ion-chelating agent that can be used to prepare reagents for ion-sensitive experiments .

HY-W004649

Tris-BOC-cyclen	Biochemical Assay Reagents	Others
Tris-BOC-cyclen is a bifunctional chelator. Bifunctional chelating agentscan be used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-W402032

Bis-Cbz-cyclen	Biochemical Assay Reagents	Others
Bis-Cbz-cyclen is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-W013178

DCTA monohydrate	Biochemical Assay Reagents	Others
DCTA monohydrate is an organic acid. DCTA refers to N,N,N',N' -tetraacetic acid, which has a strong chelating ability. DCTA monohydrate can be used as a chelating agent and coordination reagent for metal ions. DCTA monohydrate, for example, forms stable complexes with many metal ions, including calcium, magnesium and zinc. DCTA modified with ethylene glycol is selective to calcium ions in the presence of magnesium ions .

Cat. No.	Product Name	Type

HY-Y0682

Ethylenediaminetetraacetic acid

Maximum Cited Publications

8 Publications Verification

EDTA

Biochemical Assay Reagents

Ethylenediaminetetraacetic acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .

HY-W105700

Ethylenediaminetetraacetic acid sodium hydrate

5 Publications Verification

EDTA sodium hydrate

Biochemical Assay Reagents

Ethylenediaminetetraacetic acid (EDTA) sodium hydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid sodium hydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid sodium hydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid sodium hydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid sodium hydrate can be used for coronary artery disease and neural system disease research .

HY-Y0682B

Ethylenediaminetetraacetic acid tetrasodium

5 Publications Verification

EDTA tetrasodium

Biochemical Assay Reagents

Ethylenediaminetetraacetic acid (EDTA) tetrasodium is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid tetrasodium has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid tetrasodium decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid tetrasodium can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid tetrasodium can be used for coronary artery disease and neural system disease research .

HY-Y0682A

Ethylenediaminetetraacetic acid disodium dihydrate

5 Publications Verification

EDTA disodium dihydrate

Biochemical Assay Reagents

Ethylenediaminetetraacetic acid (EDTA) disodium dehydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid disodium dehydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid disodium dehydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid disodium dehydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid disodium dehydrate can be used for coronary artery disease and neural system disease research .

HY-W127819

Phenyleneethylenetriamine pentaacetic acid

Biochemical Assay Reagents

Phenyleneethylenetriamine Pentaacetic Acid is a precursor of a dual functional chelating agent .

HY-W013851

EDTA-OH	Chelators
EDTA-OH is a chelating agent, which forms thermodynamically stable chelates with metal ions like calcium, magnesium, iron, zinc and copper . EDTA-OH exhibits ability of phytoremediation in heavy-metal-contaminated soils . EDTA-OH is able to cross brain-blood barrier .

HY-W342983

ATBTA-Eu3+

Biochemical Assay Reagents

ATBTA-Eu3+ is a europium chelate that is fluorescent and can be used to label DNA .
HY-W004650

TETA hydrochloride hydrate

Chelators

TETA hydrochloride hydrate is an effective selective chelating agent for copper (II). TETA hydrochloride hydrate can be used for drug coupling .
HY-W102590

DOTMP

Chelators

DOTMP is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-W749867

Ca(Ⅱ)-EDTA disodium dihydrate Calcium disodium EDTA dihydrate	Chelators
CaⅡ-EDTA disodium dihydrate (Calcium disodium EDTA dihydrate) is an orally active metal chelating reagent, exhibits bactericidal activities against periodontal pathogens Aggregatibacter actinomycetemcomitans, Prevotella intermedia and Porphyromonas gingivalis . CaⅡ-EDTA disodium dihydrate is effective chelating antidotes for lead- and cadmium poisoning .

HY-Y0308E

Sodium phosphate dibasic, for cell culture Disodium hydrogen phosphate, for cell culture	Biochemical Assay Reagents
Sodium phosphate dibasic (Disodium hydrogen phosphate), for cell culture can be used as an excipient, such as buffer, chelating agent, can used for cell culture .

HY-W134005

Mg(Ⅱ)-EDTA disodium tetrahydrate Ethylenediaminetetraacetic acid magnesium disodium tetrahydrate	Chelators
Mg(II)-EDTA (disodium tetrahydrate) is an ion-chelating agent that can be used to prepare reagents for ion-sensitive experiments .

HY-W004649

Tris-BOC-cyclen	Chelators
Tris-BOC-cyclen is a bifunctional chelator. Bifunctional chelating agentscan be used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-W402032

Bis-Cbz-cyclen	Chelators
Bis-Cbz-cyclen is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-W013178

DCTA monohydrate

Biochemical Assay Reagents

DCTA monohydrate is an organic acid. DCTA refers to N,N,N',N' -tetraacetic acid, which has a strong chelating ability. DCTA monohydrate can be used as a chelating agent and coordination reagent for metal ions. DCTA monohydrate, for example, forms stable complexes with many metal ions, including calcium, magnesium and zinc. DCTA modified with ethylene glycol is selective to calcium ions in the presence of magnesium ions .

HY-D0973

EGTA-AM 3 Publications Verification EGTA Acetoxymethyl ester	Biochemical Assay Reagents
EGTA-AM is a membrane permeable form of EGTA, can be passively loaded into cells to generate intracellular EGTA; EGTA-AM is also a Ca ²⁺ chelator with slow chelating dynamics.

HY-W127847

Nitrilotriacetic acid trisodium salt Triglycollamic acid trisodium salt	Biochemical Assay Reagents
Nitrilotriacetic acid (Triglycollamic acid) trisodium salt is a chelating agent commonly used in various industrial processes, especially in the production of detergents, cleaners and metal plating solutions. Nitrilotriacetic acid trisodium salt has unique chemical properties that bind to metal ions, preventing them from reacting or precipitating out of solution.

HY-Y1841

o-Phenanthroline monohydrate 2 Publications Verification 1,10-Phenanthroline monohydrate	Biochemical Assay Reagents
o-Phenanthroline (1,10-Phenanthroline) monohydrate, a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline monohydrate forms a red chelate with Fe ²⁺ that absorbs maximally at 510 nm. o-Phenanthroline (1,10-Phenanthroline) monohydrate is also a MMP inhibitor .

HY-W004544

o-Phenanthroline 2 Publications Verification 1,10-Phenanthroline	Biochemical Assay Reagents
o-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline (1,10-Phenanthroline) forms a red chelate with Fe ²⁺ that absorbs maximally at 510 nm. o-Phenanthroline (1,10-Phenanthroline) is also a MMP inhibitor .

HY-W034674

Silver diethyldithiocarbamate

Silver(1+) diethyldithiocarbamate

Biochemical Assay Reagents

Silver diethyldithiocarbamate (SDDC) is an organic compound consisting of silver ions complexed with the ligand diethyldithiocarbamate. SDDC is mainly used as a reagent in analytical chemistry to detect the presence of copper, iron and other heavy metals in various materials. It acts as a chelating agent, binding to metal ions and forming stable complexes that can be easily analyzed using techniques such as UV-Vis spectroscopy.

HY-W034576

Hexacyclen hexahydrochloride

Hexaaza-18-crown-6 hexahydrochloride; 1,4,7,10,13,16-Hexaazacyclooctadecane hexahydrochloride

Biochemical Assay Reagents

Hexacyclen (Cycloalkene) is an organic compound with a unique macrocyclic structure composed of six nitrogen-containing rings. Hexacyclen is commonly used as a chelating agent in chemistry and biochemistry due to its ability to bind metal ions, and is often used to selectively bind metal ions in proteins or enzymes to study their structure and function. Hexacyclen also acts as an inhibitor of cancer .

HY-157926

Nitroso-PSAP	Chelators
Nitroso-PSAP is a sensitive and specific chromogenic reagent for iron (Fe ²⁺), which is used for the colorimetric determination of iron in blood after mineralization with periodic acid. TNitroso-PSAP chelates with iron (Fe ²⁺) to produce a green complex (λmax=756 nm, Epsilon = 4.5 x 10 < sup > 4 < / sup > dm < sup > 3 < / sup > mol < sup > 1 < / sup > cm < sup > 1 < / sup >) .

HY-W034566A

Hexacyclen trisulfate

Hexaaza-18-crown-6 trisulfate; 1,4,7,10,13,16-Hexaazacyclooctadecane trisulfate

Biochemical Assay Reagents

Hexacyclen, also known as cycloalkene, is an organic compound with a unique macrocyclic structure composed of six nitrogen-containing rings. It is commonly used as a chelating agent in chemistry and biochemistry due to its ability to bind metal ions. Inhibitors of certain diseases such as cancer. In biochemistry, Hexacyclen is often used to selectively bind metal ions in proteins or enzymes to study their structure and function. Due to its large size and complex structure, Hexacyclen is not widely used in daily products or applications.

Cat. No.	Product Name	Target	Research Area

HY-P2512A

Phytochelatin 2 (PC2) (TFA)	Peptides	Others
Phytochelatin 2 (PC2) TFA is a phytochelatin, an important heavy metal-binding peptide. Phytochelatin 2 (PC2) TFA can chelate metals, prevent metal toxicity, and maintain metal stability in the internal environment .

HY-P2512

Phytochelatin 2 (PC2)	Peptides	Others
Phytochelatin 2, a short phytochelatin, is a key plant peptide binding heavy metals. Phytochelatins are a diverse set of plant compounds that chelate metals, protect against metal toxicity and function in metal homeostasis .

HY-P3320

Phytochelatin 3

PC 3
Peptides Others

Phytochelatin 3 (PC 3) is the small metal chelating peptide that can be used for chelating heavy metals .
HY-P3320A

Phytochelatin 3 TFA

PC 3 TFA
Peptides Others

Phytochelatin 3 (PC 3) TFA is the small metal chelating peptide that can be used for chelating heavy metals .

HY-P10012

Pendetide GYK-DTPA	Peptides	Cancer
Pendetide is a chelating agent, can be conjugated with Indium (111In) Capromab for further diagnostic use. Capromab pendetide is a FDA-approved imaging agent for the detection of soft tissue metastases in prostate carcinoma .

HY-N9413

γ-Glutamyl-S-allylcysteine L-γ-Glutamyl-(S)-Allyl-Cysteine	Peptides	Metabolic Disease
γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a naturally occurring organosulfur compound found in garlic. γ-Glutamyl-S-allylcysteine has antiglycative effect and shows radical-scavenging and metal-chelating capacities .

HY-P1204

[Ala17]-MCH	MCHR1 (GPR24)	Metabolic Disease
[Ala17]-MCH, a MCH analogue (HY-P1525A), is a selective ligand for MCHR₁ (K_i=0.16 nM) over MCHR₂ (K_i=34 nM). [Eu ³⁺ chelate-labeled [Ala17]-MCH shows high affnity for MCHR₁ (K_d=0.37 nM) while has little demonstrable binding affnity for MCHR₂ .

HY-P1204A

[Ala17]-MCH TFA	MCHR1 (GPR24)	Metabolic Disease
[Ala17]-MCH TFA, a MCH analogue (HY-P1525A), is a selective ligand for MCHR₁ (K_i=0.16 nM) over MCHR₂ (K_i=34 nM). [Eu ³⁺ chelate-labeled [Ala17]-MCH shows high affnity for MCHR₁ (K_d=0.37 nM) while has little demonstrable binding affnity for MCHR₂ .

HY-W006064

(S)-2-Aminopent-4-ynoic acid	Peptides	Others
(S)-2-Aminopent-4-ynoic acid is a synthetic amino acid. (S)-2-Aminopent-4-ynoic acid can be used in synthesis of folate-conjugates and corresponding metal-chelate complexes . (S)-2-Aminopent-4-ynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y0569C

D-Gluconic acid potassium	Infection Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Saccharides Monosaccharides Cancer	Endogenous Metabolite Fungal
D-Gluconic acid potassium is an orally active carboxylic acid by the oxidation with antiseptic and chelating properties .

HY-N7059

Lactobionic acid	Infection Microorganisms Classification of Application Fields Source classification Disease Research Fields Saccharides	Bacterial
Lactobionic acid is a bionic acid naturally found in the Caspian Sea yogurt and chemically constituted of a gluconic acid bonded to a galactose. Lactobionic acid has antioxidant, antimicrobial, chelating, stabilizer, acidulant, and moisturizing properties .

HY-W012683

Iminodiacetic acid	Alkaloids Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Others
Iminodiacetic acid (IDA) is a chelating agent that strongly binds transition metals . Iminodiacetic acid can be used for removal of toxic metal ions from water . Iminodiacetic acid can serve as a biomarker to potentially predict the severity of ARDS (acute respiratory distress syndrome) .

HY-N0420

Succinic acid 4 Publications Verification Wormwood acid	Structural Classification Microorganisms Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Nervous System Disorder Endogenous metabolite Disease Research Fields Cardiovascular System Disorder Cancer	Endogenous Metabolite
Succinic acid is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid is an important platform chemical. Succinic acid can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .

HY-W015410

Disodium succinate 4 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Disodium succinate is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Disodium succinate is an intermediate product of the tricarboxylic acid cycle. Disodium succinate is an important platform chemical. Disodium succinate can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .

HY-Y0569B

D-Gluconic acid calcium hydrate	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Saccharides Monosaccharides Cancer	Fungal Endogenous Metabolite
D-Gluconic acid calcium hydrate is the carboxylic acid by the oxidation with antiseptic and chelating properties.

HY-I0301

D-(+)-Glucono-1,5-lactone Gluconic acid lactone	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Saccharides	Endogenous Metabolite Reactive Oxygen Species
D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.

HY-W007656

Cyclen	Natural Products Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields Menispermaceae Stephania japonica (Thunb.) Miers	Others
Cyclen is the aza analogue of crown ether, used as a precursor for MRI contrast agents, and is an intermediate for the preparation of effective macrocyclic chelates .

HY-N0151

Morin monohydrate	Infection Flavonols Flavonoids other families Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields Cancer	Others
Morin monohydrate, a plant-derived flavonoid, possesses low antioxidant activity. Morin is a fluorescing chelating agent used in aluminum speciation .

HY-N0621

Morin 4 Publications Verification	Flavonols Flavonoids other families Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields Cancer	Others
Morin, a plant-derived flavonoid, possesses low antioxidant activity. Morin is a fluorescing chelating agent used in aluminum speciation .

HY-N0666B

Aspartic acid calcium 2 Publications Verification Calcium L-aspartate	Cardiovascular Disease other families Microorganisms Classification of Application Fields Animals Source classification Amino acids Plants Disease Research Fields	Endogenous Metabolite
Aspartic acid calcium (Calcium L-aspartate) is a chelate where calcium is attached to an amino acid naming L-Aspartic acid. L-Aspartic acid is an amino acid and serves as a building block for proteins in the body.

HY-N9413

γ-Glutamyl-S-allylcysteine L-γ-Glutamyl-(S)-Allyl-Cysteine	Liliaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Allium sativum Linn. Plants Disease Research Fields	Others
γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a naturally occurring organosulfur compound found in garlic. γ-Glutamyl-S-allylcysteine has antiglycative effect and shows radical-scavenging and metal-chelating capacities .

HY-N7648

Atherosperminine Atherospermine	Infection Alkaloids Classification of Application Fields Source classification Fissistigma glaucescens Plants Annonaceae Disease Research Fields	Parasite
Atherosperminine（Atherospermine）is a nature occurring alkaloid, has antiplasmodial activities in vitro, with an IC₅₀ of 5.80 μM. Atherosperminine is a good reductant with the ability to chelate metals. Atherosperminine has scavenging activity towards the free radical DPPH, with an IC₅₀ of 29.56 µg/mL. Atherosperminine exerts a non-specific relaxant effect on the trachealis .

HY-N0814B

Phytic acid hexasodium Inositol hexaphosphate hexasodium; SNF472	Structural Classification other families Ketones, Aldehydes, Acids Source classification Plants	Endogenous Metabolite
Phytic acid (Inositol hexaphosphate) hexasodium is a phosphorus storage compound of seeds and cereal grains. Phytic acid hexasodium has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid hexasodium inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.

HY-N0814

Phytic acid 1 Publications Verification Inositol hexaphosphate; SNF472 free acid	Structural Classification Neurological Disease Classification of Application Fields Food Preservation Research Source classification Plants Endogenous metabolite Agricultural Research other families Microorganisms Ketones, Aldehydes, Acids Inflammation/Immunology Disease Research Fields	Xanthine Oxidase Endogenous Metabolite
Phytic acid (Inositol hexaphosphate) is a phosphorus storage compound of seeds and cereal grains. Phytic acid is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects .

HY-N10473

Pulcherriminic acid	Structural Classification Microorganisms Cyclopeptides	Bacterial Fungal
Pulcherriminic acid is a cyclic dipeptide antimicrobial agent with high affinity for Fe ³⁺, found mainly in Bacillus and yeast. Pulcherriminic acid chelates iron ions through a non-enzymatic reaction to form the extracellular red pigment pulcherrimin, which competes for iron nutrition and thus achieves an antibacterial effect. Pulcherriminic acid has great applications in food, agriculture and medical industries .

HY-N0814A

Phytic acid dodecasodium hydrate 1 Publications Verification Inositol hexaphosphate dodecasodium hydrate; SNF472 dodecasodium hydrate	Structural Classification other families Ketones, Aldehydes, Acids Source classification Plants Endogenous metabolite	Xanthine Oxidase Endogenous Metabolite
Phytic acid (Inositol hexaphosphate) dodecasodium hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects .

HY-131300

Colchicoside	Colchicaceae Source classification Gloriosa superbaL. Plants	Parasite
Colchicoside is a bioactive tropolone alkaloid with anti-leishmanial and anti-leishmanial?activities .

HY-N0123

Aloin Maximum Cited Publications 7 Publications Verification Aloin-A; Barbaloin-A	Quinones Structural Classification Liliaceae Classification of Application Fields Anthraquinones Source classification Phenols Polyphenols Aloe vera (L.) Burm. f. Plants Disease Research Fields Cancer	Others
Aloin (Aloin-A; Barbaloin-A) is a natural anti-tumor anthraquinone glycoside with iron chelating activity. Aloin induces the differentiation of MC3T3-E1 cells into osteoblasts through MAPK-mediated Wnt and Bmp signaling pathways. Alkaline phosphatase (ALP) is an early marker of osteoblast differentiation, and the activity of ALP is also enhanced by Aloin. Aloin also reduces brain edema, reduces blood-brain barrier disruption and improves cortical impact injuries. Aloin is used in research into osteoporosis and traumatic brain injury (TBI) .

HY-N0373

Licochalcone B 4 Publications Verification	Chalcones Flavonoids Leguminosae Source classification Plants Glycyrrhiza uralensis Fisch.	Amyloid-β Apoptosis NOD-like Receptor (NLR)
Licochalcone B is an extract from the root of Glycyrrhiza uralensis. Licochalcone B inhibits amyloid β (₄₂) self-aggregation (IC₅₀=2.16 μM) and disaggregate pre-formed Aβ₄₂ fibrils, reduce metal-induced Aβ₄₂ aggregation through chelating metal ionsLicochalcone B inhibits phosphorylation of NF-κB p65 in LPS signaling pathway. Licochalcone B inhibits growth and induces apoptosis of NSCLC cells. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction .

Cat. No.	Product Name	Chemical Structure

HY-B0300S

Penicillamine-d3
Penicillamine-d₃ is the deuterium labeled Penicillamine. Penicillamine (D-(-)-Penicillamine) is the most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.

HY-B0568S

Deferiprone-d3
Deferiprone-d₃ is the deuterium labeled Deferiprone. Deferiprone is the only orally active iron-chelating agent to be used therapeutically in conditions of transfusional iron overload[1][2].

HY-W030778S

Nitrilotriacetic acid-d9
Nitrilotriacetic acid-d₉ is the deuterium labeled Nitrilotriacetic acid[1]. Nitrilotriacetic acid is an aminotricarboxylic acid. Nitrilotriacetic acid can be used as a chelating agent, forming coordination compounds with metal ions[2].

HY-B1159S

Nitroxoline-D4
Nitroxoline-d₄ is the deuterium labeled Nitroxoline. Nitroxoline is an antibiotic that has proven to be very effective at combating biofilm infections. Nitroxoline functions by chelating Fe2+ and Zn2+ ions from the biofilm matrix[1][2].

HY-I0301S

D-(+)-Glucono-1,5-lactone-1-13C
D-(+)-Glucono-1,5-lactone-1- ¹³C is the ¹³C labeled D-(+)-Glucono-1,5-lactone. D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activ[1][2].

HY-W004544S

o-Phenanthroline-d8
o-Phenanthroline-d₈ is the deuterium labeled o-Phenanthroline. o-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline (1,10-Phenanthroline) forms a red chelate with Fe2+ that absorbs maximally at 510 nm. o-Phenanthroline (1,10-Phenanthroline) is also a MMP inhibitor[1][2].

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