Search Result

Results for "

Coffee

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (1) Apoptosis (2) Bacterial (2) Biochemical Assay Reagents (1) Calcium Channel (1) COX (1) Drug Metabolite (1) Endogenous Metabolite (5) ERK (1) Fluorescent Dye (1) Fungal (1) HSV (1) Isotope-Labeled Compounds (2) Monoamine Oxidase (1) NF-κB (1) PGE synthase (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (2) Infection (5) Inflammation/Immunology (5) Metabolic Disease (3) Neurological Disease (2)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W001663

4'-Hydroxy-3'-methylacetophenone	Bacterial	Infection
4'-Hydroxy-3'-methylacetophenone, a phenolic volatile compound, is isolated from Hawaiian green coffee beans (Coffea Arabica L.). 4'-Hydroxy-3'-methylacetophenone has potent antioxidant activities. 4'-Hydroxy-3'-methylacetophenone also can be used to synthesize heterocyclic compounds which have antimycobacterial activity .

HY-N0464

D-(-)-Quinic acid 1 Publications Verification	Endogenous Metabolite	Infection Inflammation/Immunology
D-(-)-Quinic acid is a cyclohexanecarboxylic acid and is implicated in the perceived acidity of coffee.

HY-113340

2-Furoylglycine

Endogenous Metabolite Others

2-Furoylglycine, a urinary metabolite in human, is a putative biomarker for coffee consumption .
HY-116056

16-O-Methylcafestol

Others Others

16-O-Methylcafestol is a derivative of cafestol that can be isolated from green coffee beans .

2-Furoylglycine	Endogenous Metabolite	Others
2-Furoylglycine, a urinary metabolite in human, is a putative biomarker for coffee consumption .

16-O-Methylcafestol	Others	Others
16-O-Methylcafestol is a derivative of cafestol that can be isolated from green coffee beans .

HY-N4241

Kauran-18-oic acid, 16,17,19-trihydroxy-, (4α)-	Others	Others
Kauran-18-oic acid, 16,17,19-trihydroxy-, (4α)- (compound 5) is a endogenous ent-kaurane diterpene compound in green coffee beans, providing direct chemical indicators of low-quality coffee .

HY-W010608

2-Methyltetrahydrofuran-3-one

Others Others

2-Methyltetrahydrofuran-3-one is one of the volatile constituents of roasted coffee .
HY-113472

N-Methyl-4-pyridone-3-carboxamide

Drug Metabolite Others

N-Methyl-4-pyridone-3-carboxamide is a metabolite of coffee pyridines .

2-Methyltetrahydrofuran-3-one	Others	Others
2-Methyltetrahydrofuran-3-one is one of the volatile constituents of roasted coffee .

N-Methyl-4-pyridone-3-carboxamide	Drug Metabolite	Others
N-Methyl-4-pyridone-3-carboxamide is a metabolite of coffee pyridines .

HY-N0464S

Quinic acid-13C3	Endogenous Metabolite	Infection Inflammation/Immunology
Quinic acid- ¹³C₃ is the ¹³C-labeled D-(-)-Quinic acid. D-(-)-Quinic acid is a cyclohexanecarboxylic acid and is implicated in the perceived acidity of coffee.

HY-W010451

1,2,4-Trihydroxybenzene	Calcium Channel	Cardiovascular Disease
1,2,4-Trihydroxybenzene (Hydroxyhydroquinone), a by-product of coffee bean roasting, increases intracellular Ca ²⁺ concentration in rat thymic lymphocytes .

HY-W017389

Xanthine 3 Publications Verification	Endogenous Metabolite	Inflammation/Immunology
Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation .

HY-N0415S

Trigonelline-d3 chloride Trigonelline-d₃ hydrochloride	Isotope-Labeled Compounds HSV Bacterial Fungal	Infection Metabolic Disease Cancer
Trigonelline-d₃ (chloride) is the deuterium labeled Trigonelline chloride. Trigonelline chloride, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee. Trigonelline chloride has anti-HSV-1 , antibacterial, and antifungal activities.

HY-N6257

Cafestol 1 Publications Verification	ERK PGE synthase COX NF-κB	Inflammation/Immunology Cancer
Cafestol, one of the major components of coffee, is a coffee-specific diterpene from. Cafestol is a ERK inhibitor for AP-1-targeted activity against PGE₂ production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE₂ production by suppressing the NF-kB activation pathway. Cafestol contributes to its beneficial effects through various biological activities such as chemopreventive, antitumorigenic, hepatoprotective, antioxidative and antiinflammatory effects .

HY-N10044

3-Feruloyl-4-caffeoylquinic acid

Others Others

3-Feruloyl-4-caffeoylquinic acidis acaffeoyl, feruloyl quinic acidderivativeisolated fromroasted C.arabica .

3-Feruloyl-4-caffeoylquinic acid	Others	Others
3-Feruloyl-4-caffeoylquinic acidis acaffeoyl, feruloyl quinic acidderivativeisolated fromroasted C.arabica .

HY-W016278

Gamma-undecalactone	Biochemical Assay Reagents	Others
Gamma-undecalactone consists of a five-membered dihydrofuran ring with an ester group and a heptyl chain. This compound has a fruity smell and is commonly used as a flavor additive in various food and beverage products such as coffee, tea and baked goods.

HY-Y1426

2'-Hydroxyacetophenone o-Hydroxyacetophenone; o-Acetylphenol
2'-Hydroxyacetophenone is found in alcoholic beverages. 2'-Hydroxyacetophenone is present in tomato, cassia, fried beef, rum, whiskey, cocoa, coffee and black tea. 2'-Hydroxyacetophenone is a flavouring ingredient. Building block in chemical synthesis.

HY-N6258

Kahweol	AMPK Apoptosis	Metabolic Disease
Kahweol is one of the consituents of the coffee from Coffea Arabica with anti-inflammatory anti-angiogenic, and anti-cancerous activities. Kahweol inhibits adipogenesis and increase glucose uptake by AMP-activated protein kinase (AMPK) activation. Kahweol induces apoptosis.

HY-Y0543

5-Methylfurfural 1 Publications Verification
5-Methylfurfural is a naturally occurring substance, found in cigarette smoke condensate, licorice essential oil, stored dehydrated orange powder, baked potato flour, volatile compounds of roast beef, aroma concentrate of sponge cake. bread and in coffee, tea and cocoa . A flavoring agent.

HY-Y0949

Methyl 2-furoate 1 Publications Verification Methyl furan-2-carboxylate
Methyl 2-furoate (Methyl furan-2-carboxylate) is a building block in chemical synthesis. A flavoring agent in food. Found in cranberries, guava fruits, raisins and other fruits. Also present in baked potato, roasted filberts, roasted peanut, tomatoes, coffee, cocoa, okra, etc.

HY-N0264

Ligustrazine 5 Publications Verification Chuanxiongzine; Tetramethylpyrazine	Apoptosis	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Ligustrazine (Chuanxiongzine), an alkylpyrazine isolated from Ligusticum chuanxiong Hort. (Chuan Xiong) , is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Ligustrazine also has potential nootropic and anti-inflammatory activities in rats .

HY-W012998

2,3-Pentanedione	Others	Others
2,3-Pentanedione is a common constituent of synthetic flavorings and is used to impart a butter, strawberry, caramel, fruit, rum, or cheese flavor in beverages, ice cream, candy, baked goods, gelatins, and puddings. 2,3-Pentanedione also occurs naturally as a fermentation product in beer, wine, and yogurt and is releasedduring roasting of coffee beans .

HY-W008566

Norharmane Norharman; β-Carboline	Monoamine Oxidase Endogenous Metabolite	Infection Neurological Disease Cancer
Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC₅₀ values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .

HY-D2264

Caffeine orange	Fluorescent Dye	Others
Caffeine orange (Compound 1) is an aqueous-phase fluorescence turn-on sensor for caffeine that is highly selective to caffeine. Caffeine orange makes caffeinated coffee appear orange when exposed to 532 nM of green excitation light. Caffeine orange has excellent photophysical properties such as high extinction coefficient, high light stability and narrow emission bandwidth, which can be used in the research of caffeine detection devices 。

HY-W012998S

2,3-Pentanedione-d5	Isotope-Labeled Compounds	Others
2,3-Pentanedione-d₅ is the deuterium labeled 2,3-Pentanedione[1]. 2,3-Pentanedione is a common constituent of synthetic flavorings and is used to impart a butter, strawberry, caramel, fruit, rum, or cheese flavor in beverages, ice cream, candy, baked goods, gelatins, and puddings. 2,3-Pentanedione also occurs naturally as a fermentation product in beer, wine, and yogurt and is releasedduring roasting of coffee beans[2].

Caffeine orange	Fluorescent Dyes/Probes
Caffeine orange (Compound 1) is an aqueous-phase fluorescence turn-on sensor for caffeine that is highly selective to caffeine. Caffeine orange makes caffeinated coffee appear orange when exposed to 532 nM of green excitation light. Caffeine orange has excellent photophysical properties such as high extinction coefficient, high light stability and narrow emission bandwidth, which can be used in the research of caffeine detection devices 。

Gamma-undecalactone	Biochemical Assay Reagents
Gamma-undecalactone consists of a five-membered dihydrofuran ring with an ester group and a heptyl chain. This compound has a fruity smell and is commonly used as a flavor additive in various food and beverage products such as coffee, tea and baked goods.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W001663

4'-Hydroxy-3'-methylacetophenone	Infection Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Rubiaceae Phenols Plants Disease Research Fields Coffea arabica L.	Bacterial
4'-Hydroxy-3'-methylacetophenone, a phenolic volatile compound, is isolated from Hawaiian green coffee beans (Coffea Arabica L.). 4'-Hydroxy-3'-methylacetophenone has potent antioxidant activities. 4'-Hydroxy-3'-methylacetophenone also can be used to synthesize heterocyclic compounds which have antimycobacterial activity .

HY-N0464

D-(-)-Quinic acid 1 Publications Verification	Infection other families Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
D-(-)-Quinic acid is a cyclohexanecarboxylic acid and is implicated in the perceived acidity of coffee.

HY-113340

2-Furoylglycine	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Furoylglycine, a urinary metabolite in human, is a putative biomarker for coffee consumption .

HY-116056

16-O-Methylcafestol	Structural Classification Terpenoids Coffea canephora Pierre ex Froehn. Source classification Rubiaceae Diterpenoids Plants	Others
16-O-Methylcafestol is a derivative of cafestol that can be isolated from green coffee beans .

HY-N4241

Kauran-18-oic acid, 16,17,19-trihydroxy-, (4α)-	other families Classification of Application Fields Terpenoids Source classification Other Diseases Diterpenoids Plants Disease Research Fields	Others
Kauran-18-oic acid, 16,17,19-trihydroxy-, (4α)- (compound 5) is a endogenous ent-kaurane diterpene compound in green coffee beans, providing direct chemical indicators of low-quality coffee .

HY-W010608

2-Methyltetrahydrofuran-3-one	other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Plants Disease Research Fields	Others
2-Methyltetrahydrofuran-3-one is one of the volatile constituents of roasted coffee .

HY-W010451

1,2,4-Trihydroxybenzene	Cardiovascular Disease Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	Calcium Channel
1,2,4-Trihydroxybenzene (Hydroxyhydroquinone), a by-product of coffee bean roasting, increases intracellular Ca ²⁺ concentration in rat thymic lymphocytes .

HY-W017389

Xanthine 3 Publications Verification	Structural Classification Natural Products Classification of Application Fields Source classification Endocrine diseases Plants Camellia sinensis (L.) O. Ktze. Endogenous metabolite Microorganisms Disease markers Nervous System Disorder Inflammation/Immunology Disease Research Fields Theaceae	Endogenous Metabolite
Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation .

HY-N6257

Cafestol 1 Publications Verification	Classification of Application Fields Terpenoids Rubiaceae Diterpenoids Plants Inflammation/Immunology Disease Research Fields Cancer	ERK PGE synthase COX NF-κB
Cafestol, one of the major components of coffee, is a coffee-specific diterpene from. Cafestol is a ERK inhibitor for AP-1-targeted activity against PGE₂ production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE₂ production by suppressing the NF-kB activation pathway. Cafestol contributes to its beneficial effects through various biological activities such as chemopreventive, antitumorigenic, hepatoprotective, antioxidative and antiinflammatory effects .

HY-N10044

3-Feruloyl-4-caffeoylquinic acid	Structural Classification Coffea canephora Pierre ex Froehn. Source classification Rubiaceae Phenols Polyphenols Plants	Others
3-Feruloyl-4-caffeoylquinic acidis acaffeoyl, feruloyl quinic acidderivativeisolated fromroasted C.arabica .

HY-N6258

Kahweol	other families Classification of Application Fields Terpenoids Source classification Rubiaceae Metabolic Disease Diterpenoids Plants Disease Research Fields Coffea arabica L.	AMPK Apoptosis
Kahweol is one of the consituents of the coffee from Coffea Arabica with anti-inflammatory anti-angiogenic, and anti-cancerous activities. Kahweol inhibits adipogenesis and increase glucose uptake by AMP-activated protein kinase (AMPK) activation. Kahweol induces apoptosis.

HY-N0264

Ligustrazine 5 Publications Verification Chuanxiongzine; Tetramethylpyrazine	Cardiovascular Disease Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Metabolic Disease Dicerothamnus rhinocerotis Plants Umbelliferae Inflammation/Immunology Disease Research Fields	Apoptosis
Ligustrazine (Chuanxiongzine), an alkylpyrazine isolated from Ligusticum chuanxiong Hort. (Chuan Xiong) , is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Ligustrazine also has potential nootropic and anti-inflammatory activities in rats .

HY-W012998

2,3-Pentanedione	other families Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Plants Disease Research Fields	Others
2,3-Pentanedione is a common constituent of synthetic flavorings and is used to impart a butter, strawberry, caramel, fruit, rum, or cheese flavor in beverages, ice cream, candy, baked goods, gelatins, and puddings. 2,3-Pentanedione also occurs naturally as a fermentation product in beer, wine, and yogurt and is releasedduring roasting of coffee beans .

HY-W008566

Norharmane Norharman; β-Carboline	Structural Classification Neurological Disease Classification of Application Fields Source classification Pyridine Alkaloids Endogenous metabolite Biological Pesticide Research Indole Alkaloids Agricultural Research Infection Alkaloids Microorganisms Disease Research Fields Cancer	Monoamine Oxidase Endogenous Metabolite
Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC₅₀ values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .

Cat. No.	Product Name	Chemical Structure

HY-N0415S

Trigonelline-d3 chloride
Trigonelline-d₃ (chloride) is the deuterium labeled Trigonelline chloride. Trigonelline chloride, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee. Trigonelline chloride has anti-HSV-1 , antibacterial, and antifungal activities.

HY-N0464S

Quinic acid-13C3

Quinic acid- ¹³C₃ is the ¹³C-labeled D-(-)-Quinic acid. D-(-)-Quinic acid is a cyclohexanecarboxylic acid and is implicated in the perceived acidity of coffee.

Quinic acid-13C3
Quinic acid- ¹³C₃ is the ¹³C-labeled D-(-)-Quinic acid. D-(-)-Quinic acid is a cyclohexanecarboxylic acid and is implicated in the perceived acidity of coffee.

HY-W012998S

2,3-Pentanedione-d5
2,3-Pentanedione-d₅ is the deuterium labeled 2,3-Pentanedione[1]. 2,3-Pentanedione is a common constituent of synthetic flavorings and is used to impart a butter, strawberry, caramel, fruit, rum, or cheese flavor in beverages, ice cream, candy, baked goods, gelatins, and puddings. 2,3-Pentanedione also occurs naturally as a fermentation product in beer, wine, and yogurt and is releasedduring roasting of coffee beans[2].

2,3-Pentanedione-d5

2,3-Pentanedione-d₅ is the deuterium labeled 2,3-Pentanedione[1]. 2,3-Pentanedione is a common constituent of synthetic flavorings and is used to impart a butter, strawberry, caramel, fruit, rum, or cheese flavor in beverages, ice cream, candy, baked goods, gelatins, and puddings. 2,3-Pentanedione also occurs naturally as a fermentation product in beer, wine, and yogurt and is releasedduring roasting of coffee beans[2].

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Coffee

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Natural
Products