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Results for "

Cough

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Angiotensin-converting Enzyme (ACE) (2) Apoptosis (4) Arp2/3 Complex (1) Autophagy (2) Bacterial (3) Biochemical Assay Reagents (1) Calcium Channel (1) Cannabinoid Receptor (1) Dopamine Receptor (1) Eukaryotic Initiation Factor (eIF) (1) Histamine Receptor (2) HIV (2) HSP (1) Influenza Virus (1) Interleukin Related (1) Isotope-Labeled Compounds (4) mAChR (5) mGluR (1) MicroRNA (1) Mucin (1) Neurokinin Receptor (3) NF-κB (2) Opioid Receptor (1) P2X Receptor (8) p38 MAPK (1) PARP (1) Potassium Channel (2) SARS-CoV (2) Sigma Receptor (3) Sodium Channel (1) TNF Receptor (1) Topoisomerase (1) TRP Channel (1)
By Research Areas:	Cancer (6) Cardiovascular Disease (5) Endocrinology (3) Infection (6) Inflammation/Immunology (32) Metabolic Disease (4) Neurological Disease (19)

By Targets:

Adrenergic Receptor (1)

Angiotensin-converting Enzyme (ACE) (2)

Apoptosis (4)

Arp2/3 Complex (1)

Autophagy (2)

Bacterial (3)

Biochemical Assay Reagents (1)

Calcium Channel (1)

Cannabinoid Receptor (1)

Dopamine Receptor (1)

Eukaryotic Initiation Factor (eIF) (1)

Histamine Receptor (2)

HIV (2)

HSP (1)

Influenza Virus (1)

Interleukin Related (1)

Isotope-Labeled Compounds (4)

mAChR (5)

mGluR (1)

MicroRNA (1)

Mucin (1)

Neurokinin Receptor (3)

NF-κB (2)

Opioid Receptor (1)

P2X Receptor (8)

p38 MAPK (1)

PARP (1)

Potassium Channel (2)

SARS-CoV (2)

Sigma Receptor (3)

Sodium Channel (1)

TNF Receptor (1)

Topoisomerase (1)

TRP Channel (1)

By Research Areas:

Cancer (6)

Cardiovascular Disease (5)

Endocrinology (3)

Infection (6)

Inflammation/Immunology (32)

Metabolic Disease (4)

Neurological Disease (19)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-121376

Neoamygdalin	Others	Inflammation/Immunology
Neoamygdalin is a compound identified in the different processed bitter almonds. Neoamygdalin has the potential for the research of cough and asthma .

HY-B0264

Guaifenesin Guaiacol glyceryl ether; Guaiphenesin; Glycerol guaiacolate	Mucin	Neurological Disease Inflammation/Immunology
Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough .

HY-109170

Eliapixant BAY 1817080	P2X Receptor	Inflammation/Immunology
Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC₅₀ of 8 nM. Eliapixant can be used for the research of refractory chronic cough .

HY-W181871

Piperidione

Others Others

Piperidione is a cough agent .

Piperidione	Others	Others
Piperidione is a cough agent .

HY-N10620

Melitidin	Others	Inflammation/Immunology
Melitidin is a flavanone glycoside, that can be isolated from Citrus grandis 'Tomentosa'. Melitidin shows a good antitussive effect on cough induced by citric acid in Guinea pig .

HY-B1042

Oxolamine citrate SKF-9976 citrate; AF-438 citrate	Others	Inflammation/Immunology
Oxolamine citrate (SKF-9976 citrate) is a cough suppressant that can be used for the research of respiratory tract diseases. Oxolamine citrate also exhibits anti-inflammatory effect .

HY-B0372

Bromhexine	Others	Inflammation/Immunology
Bromhexine is a potent expectorant. Bromhexine increase mucociliary clearance and reduces cough. Bromhexine can be used in study various respiratory diseases .

HY-A0161A

Chlophedianol hydrochloride Clofedanol hydrochloride; Calmotusin hydrochloride; NSC 113595 hydrochloride	Others	Infection
Chlophedianol (Clofedanol) hydrochloride is an orally active and potent antitussive agent. Chlophedianol hydrochloride can be used for the research of acute cough due to upper respiratory tract infections (URIs) .

HY-148144

Clobutinol	Potassium Channel	Cardiovascular Disease Inflammation/Immunology
Clobutinol is a compound that has anti-tussive effects. Clobutinol affects heart rate and blood pressure, it can be used for cough related research .

HY-148144A

Clobutinol hydrochloride	Potassium Channel	Cardiovascular Disease Inflammation/Immunology
Clobutinol hydrochloride is a compound that has anti-tussive effects. Clobutinol hydrochloride affects heart rate and blood pressure, it can be used for cough related research .

HY-B1216

Oxeladin citrate	Sigma Receptor	Cardiovascular Disease Others Neurological Disease
Oxeladin citrate is an orally active and brain-penetrant cough suppressant as well as a selective sigma 1 receptor agonist (K_i = 25 nM). Oxeladin can be used for pulmonary diseases and stroke research .

HY-107798

Potassium guaiacolsulfonate hemihydrate	Bacterial	Infection
Potassium guaiacolsulfonate hemihydrate is an orally active expectorant used for acute respiratory tract infections. Potassium guaiacolsulfonate hemihydrate helps loosen mucus and used for a cough caused by the common cold, infections or allergies in combination with other agents .

HY-108668

TC-P 262	P2X Receptor	Others
TC-P 262 is a potent P2X3 inhibitor. TC-P 262 shows inhibition by bindings to hP2X3. TC-P 262 has the potential for the research of rheumatoid arthritis, cough, and pain .

HY-136026

Camlipixant BLU-5937	P2X Receptor	Inflammation/Immunology
Camlipixant (BLU-5937) a potent, selective, non-competitive and orally active P2X3 homotrimeric receptor antagonist with an IC₅₀ of 25 nM against hP2X3 homotrimeric. Camlipixant shows potent anti-tussive effect and no taste alteration. Camlipixant can be used for the research of unexplained, refractory chronic cough .

HY-B0372A

Bromhexine hydrochloride 3 Publications Verification	SARS-CoV Autophagy HIV	Metabolic Disease
Bromhexine hydrochloride is a potent and specific TMPRSS2 protease inhibitor with an IC₅₀ of 0.75 μM. Bromhexine hydrochloride can prevent and manage SARS-CoV-2 infection. Bromhexine hydrochloride is an autophagy agonist. Bromhexine hydrochloride is a mucolytic cough suppressant and has the potential for a range of respiratory conditions .

HY-143481

Nav1.8-IN-2	Sodium Channel	Neurological Disease
Nav1.8-IN-2 (compound 35A) is a potent Na_v1.8 inhibitor with an IC₅₀ value of 0.4 nM. Nav1.8-IN-2 can be used for researching pain disorders, cough disorders, and acute and chronic itch disorders .

HY-115877

GDC-0334	TRP Channel	Others
GDC-0334 is a selective TRPA1 antagonist. GDC-0334 inhibits TRPA1 function on airway smooth muscle and sensory neurons by decreasing cough and allergic airway inflammation in rats and guinea pigs. GDC-0334 can be used for TRPA1-mediated diseases research, such as pain or asthma .

HY-N12081

Oxyresveratrol 4-O-β-D-glucopyranoside	Biochemical Assay Reagents	Metabolic Disease Inflammation/Immunology
Oxyresveratrol 4-O-β-D-glucopyranoside (compound 3) is a natural product that can be obtained from the root bark of Morus atropurpurea. Oxyresveratrol 4-O-β-D-glucopyranoside has potential in studies of diabetes, arthritis, rheumatism, cough and headache .

HY-101588

Gefapixant MK-7264; AF-219	P2X Receptor	Inflammation/Immunology
Gefapixant is an orally active and potent purinergic P2X3 receptor (P2X3R) antagonist, with IC₅₀ values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant can be used for the research of chronic cough and knee osteoarthritis .

HY-101588A

Gefapixant citrate MK-7264 citrate; AF-219 citrate	P2X Receptor	Inflammation/Immunology
Gefapixant citrate is an orally active and potent purinergic P2X3 receptor (P2X3R) antagonist, with IC₅₀ values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant citrate can be used for the research of chronic cough and knee osteoarthritis .

HY-12844

Ro 64-6198 1 Publications Verification	Opioid Receptor	Neurological Disease
Ro 64-6198 is a potent, selective, nonpeptide, high-affinity, high cellular permeability and brain penetration N/OFQ receptor (NOP) agonist with an EC₅₀ value of 25.6 nM. Ro 64-6198 is at least 100 times more selective for the NOP receptor over the classic opioid receptors. Ro 64-6198 can be used for stress and anxiety, addiction, neuropathic pain, cough, and anorexia .

HY-136587

Oxomemazine	Histamine Receptor mGluR	Inflammation/Immunology
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic properties. Oxomemazine is a selective antagonist for muscarinic M1 receptor, displays about 20-fold difference in the affinity for high (K_i= 84 nM, M1 receptor) and low (K_i= 1.65 μM, M2 receptor) affinity sites . Oxomemazine an antihistamine and anticholinergic agent used for the study of cough treatment .

HY-B0264S

Guaifenesin-d3 Guaiacol glyceryl ether-d₃; Guaiphenesin-d₃; Glycerol guaiacolate-d₃	Isotope-Labeled Compounds	Neurological Disease Inflammation/Immunology
Guaifenesin-d₃ is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough[1][2].

HY-N0214

Peimisine 2 Publications Verification Ebeiensine	mAChR Angiotensin-converting Enzyme (ACE) Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
Peimisine (Ebeiensine) is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research .

HY-N0214A

Peimisine hydrochloride Ebeiensine hydrochloride	mAChR Angiotensin-converting Enzyme (ACE) Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
Peimisine (Ebeiensine) hydrochloride is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine hydrochloride shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research .

HY-114657A

Benproperine phosphate	Arp2/3 Complex	Inflammation/Immunology Cancer
Benproperine phosphate is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. Benproperine phosphate attenuates the actin polymerization rate of action polymerization nucleation by impairing Arp2/3 function. Benproperine phosphate has the potential for a cough suppressant and suppresses cancer cell migration and tumor metastasis .

HY-B2115

Sulfogaiacol

Bacterial Inflammation/Immunology

Sulfogaiacol is a antitussive agent. Sulfogaiacol is used for acute respiratory tract infections, cough and other conditions.

Sulfogaiacol	Bacterial	Inflammation/Immunology
Sulfogaiacol is a antitussive agent. Sulfogaiacol is used for acute respiratory tract infections, cough and other conditions.

HY-134004

Pentoxyverine Carbetapentane	Sigma Receptor mAChR	Neurological Disease Inflammation/Immunology
Pentoxyverine (Carbetapentane) is an orally active sigma-1 receptor agonist, with K_is of 41 nM, 894 nM and 75 nM for σ1, σ2 and guinea-pig brain membran σ1, respectively. Pentoxyverine is a muscarinic antagonist. Pentoxyverine is a potent antitussive, anticonvulsant, and spasmolytic agent. Pentoxyverine can be used for inhibiting bronchial interceptor, weakening of cough reflex, bronchial smooth muscle relaxation and reduction of airway resistance .

HY-B0264R

Guaifenesin (Standard) Guaiacol glyceryl ether(Standard); Guaiphenesin(Standard); Glycerol guaiacolate (Standard)	Others	Neurological Disease Inflammation/Immunology
Guaifenesin (Standard) is the analytical standard of Guaifenesin. This product is intended for research and analytical applications. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough .

HY-B0264S1

Guaifenesin-d5	Isotope-Labeled Compounds	Neurological Disease Inflammation/Immunology
Guaifenesin-d₅ is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough. Guaifenesin also has narcotic effect[1][2].

HY-B1055

Pentoxyverine citrate Carbetapentane citrate	Sigma Receptor mAChR	Neurological Disease Inflammation/Immunology
Pentoxyverine (Carbetapentane) citrate is an orally active sigma-1 receptor agonist, with K_is of 41 nM, 894 nM and 75 nM for σ1, σ2 and guinea-pig brain membrane σ1, respectively. Pentoxyverine citrate is a muscarinic antagonist. Pentoxyverine citrate is a potent antitussive, anticonvulsant, and spasmolytic agent. Pentoxyverine citrate can be used for inhibiting bronchial interceptor, weakening of cough reflex, bronchial smooth muscle relaxation and reduction of airway resistance .

HY-106873

Nepinalone

Others Others

Nepinalone, an alchilaminate derivative of β-tetralone and an orally active cough suppressant, possesses a non-opioid antitussive activity .

Nepinalone	Others	Others
Nepinalone, an alchilaminate derivative of β-tetralone and an orally active cough suppressant, possesses a non-opioid antitussive activity .

HY-106873A

Nepinalone hydrochloride	Others	Others
Nepinalone hydrochloride, an alchilaminate derivative of β-tetralone and an orally active cough suppressant, possesses a non-opioid antitussive activity .

HY-B1032

Dropropizine (±)-Dropropizine; UCB-196	Others	Neurological Disease
Dropropizine ((±)-Dropropizine) is a peripheral antitussive agent that acts by inhibiting cough reflex through its action on the peripheral receptors and their afferent conductors .

HY-111811

Homomangiferin	Others	Inflammation/Immunology
Homomangiferin is mangiferin monomethyl ether. Homomangiferin has important medicinal properties and is widely used to relieve many symptoms, for example coughing and asthma .

HY-N0829

Shionone	Others	Inflammation/Immunology
Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities . Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure .

HY-B2090

Pipazethate SKF 70230A; SQ 15874; Pipazetate
Pipazethate (SKF 70230A), a pyridobenzothiazine derivative, is a potent GABA antagonist. Pipazethate has antitussive activity. Pipazethate can be used in research in cough supressant .

HY-101765

GW 833972A	Cannabinoid Receptor	Neurological Disease
GW 833972A is a selective CB2 receptor agonist. GW 833972A inhibits induced nerve depolarization and citric acid-induced cough in animal models .

HY-A0161

Chlophedianol Clofedanol; Calmotusin; NSC 113595
Chlophedianol (Clofedanol) is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs) .

HY-N0081

(±)-Praeruptorin A	Calcium Channel	Infection
(±)-Praeruptorin A is the di-esterified product of cis-khellactone (CKL) and the major active ingredient in Peucedani Radix which consists of the dried roots of Peucedanum praeruptorumDunn (Apiaceae). (±)-Praeruptorin A has been widely employed as one of the famous traditional Chinese medicines (TCMs) for the treatment of cough with thick sputum and dyspnea, nonproductive cough and upper respiratory infections for centuries in China. (±)-Praeruptorin A has dramatically therapeutic effects on hypertension mainly through acting as a Ca ²⁺-influx blocker .

HY-W354753

Homatropine hydrochloride	mAChR	Others
Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs .

HY-N7593

Tectoruside	Others	Inflammation/Immunology
Tectoruside is a phenol acid glycoside of the rhizome of Iris dichotoma Pall. Iris dichotoma Pall, a traditional Chinese herbal medicine, has been used in several disorders such as inflammation, throat disorders, asthma and coughs .

HY-106659

SCH 900978 NK-1 Antagonist 1	Neurokinin Receptor	Neurological Disease Endocrinology
SCH 900978 (NK-1 Antagonist 1) is an antagonist of NK-1 receptor, used in the research of NK-1 related diseases and conditions such as cough, overactive bladder, alcohol dependency and depression .

HY-B1551

Benzonatate Benzononatine
Benzonatate (Benzononatine) is a peripheral oral antitussive that dampens the activity of cough stretch receptors. Benzonatate has sodium channel-blocking properties and local anesthetic effects on the respiratory stretch receptors due to a tetracaine-like metabolite .

HY-B1032R

Dropropizine (Standard) (±)-Dropropizine (Standard); UCB-196 (Standard)	Others	Neurological Disease
Dropropizine (Standard) is the analytical standard of Dropropizine. This product is intended for research and analytical applications. Dropropizine ((±)-Dropropizine) is a peripheral antitussive agent that acts by inhibiting cough reflex through its action on the peripheral receptors and their afferent conductors .

HY-N8624

Ethyl 3,4-dicaffeoylquinate	Bacterial	Others
Ethyl 3,4-dicaffeoylquinate is a phenolic acid isolated from G. divaricata. G. divaricata is one of the famous traditional Chinese herbs, usually used for bronchitis, tuberculosis, twisted knot cough, rheumatism, diabetes, etc .

HY-N0212

Peimine 1 Publications Verification Verticine; Dihydroisoimperialine	Apoptosis Interleukin Related TNF Receptor p38 MAPK NF-κB	Inflammation/Immunology Cancer
Peimine (Verticine; Dihydroisoimperialine) is an orally active natural product. Peimine has anti-inflammatory, analgesic and cough relieving effects. Peimine can be used in cancer and inflammation related research .

HY-B1895

Levodropropizine (S)-(-)-Dropropizine; DF-526	Histamine Receptor	Neurological Disease Inflammation/Immunology Endocrinology
Levodropropizine (DF-526) is an orally active histamine receptor inhibitor, Levodropropizine is an effective and very well tolerated peripheral antitussive agent .

HY-137451A

(E/Z)-Sivopixant (E/Z)-S-600918	P2X Receptor	Inflammation/Immunology
(E/Z)-Sivopixant ((E/Z)-S-600918) is a potent P2X3 receptor antagonist with an IC₅₀ of 4 nM. (E/Z)-Sivopixant can be used for respiratory diseases research .

HY-112779

Pertussis Toxin	Others	Infection
Pertussis Toxin is a protein-based AB₅-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. Pertussis Toxin inhibits G protein-coupled receptor (GPR) signaling through Gi proteins .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-121376

Neoamygdalin	Alkaloids Classification of Application Fields Source classification Rosaceae Plants Prunus armeniaca L. Disease Research Fields Inflammation/Immunology Food Research	Others
Neoamygdalin is a compound identified in the different processed bitter almonds. Neoamygdalin has the potential for the research of cough and asthma .

HY-B0264

Guaifenesin Guaiacol glyceryl ether; Guaiphenesin; Glycerol guaiacolate	Guaiacum officinale L. Structural Classification Natural Products other families Neurological Disease Classification of Application Fields Zygophyllaceae Source classification Plants Inflammation/Immunology Disease Research Fields	Mucin
Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough .

HY-N0214

Peimisine 2 Publications Verification Ebeiensine	Alkaloids Piperidine Alkaloids Liliaceae Classification of Application Fields Source classification Plants Inflammation/Immunology Disease Research Fields Fritillaria cirrhosa	mAChR Angiotensin-converting Enzyme (ACE) Apoptosis
Peimisine (Ebeiensine) is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research .

HY-N10620

Melitidin	Structural Classification Flavonoids Citrus maxima (Burm.) Merr. Flavones Rutaceae Plants	Others
Melitidin is a flavanone glycoside, that can be isolated from Citrus grandis 'Tomentosa'. Melitidin shows a good antitussive effect on cough induced by citric acid in Guinea pig .

HY-N12081

Oxyresveratrol 4-O-β-D-glucopyranoside	Structural Classification Source classification Phenols Polyphenols Plants Moraceae Morus alba Linn.	Biochemical Assay Reagents
Oxyresveratrol 4-O-β-D-glucopyranoside (compound 3) is a natural product that can be obtained from the root bark of Morus atropurpurea. Oxyresveratrol 4-O-β-D-glucopyranoside has potential in studies of diabetes, arthritis, rheumatism, cough and headache .

HY-N0214A

Peimisine hydrochloride Ebeiensine hydrochloride	Alkaloids Piperidine Alkaloids Liliaceae Classification of Application Fields Source classification Plants Fritillaria ussuriensis Maxim. Inflammation/Immunology Disease Research Fields	mAChR Angiotensin-converting Enzyme (ACE) Apoptosis
Peimisine (Ebeiensine) hydrochloride is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine hydrochloride shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research .

HY-B0264R

Guaifenesin (Standard) Guaiacol glyceryl ether(Standard); Guaiphenesin(Standard); Glycerol guaiacolate (Standard)	Guaiacum officinale L. Structural Classification Natural Products other families Neurological Disease Classification of Application Fields Zygophyllaceae Source classification Plants Inflammation/Immunology Disease Research Fields	Others
Guaifenesin (Standard) is the analytical standard of Guaifenesin. This product is intended for research and analytical applications. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough .

HY-111811

Homomangiferin	other families Xanthones Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology	Others
Homomangiferin is mangiferin monomethyl ether. Homomangiferin has important medicinal properties and is widely used to relieve many symptoms, for example coughing and asthma .

HY-N0829

Shionone	Structural Classification Classification of Application Fields Terpenoids Diterpenoids Plants Compositae Inflammation/Immunology Disease Research Fields Sesbania vesicaria (Jacq.) Elliott	Others
Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities . Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure .

HY-N0081

(±)-Praeruptorin A	Infection Chrysanthemum × morifolium (Ramat.) Hemsl. Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Umbelliferae Disease Research Fields	Calcium Channel
(±)-Praeruptorin A is the di-esterified product of cis-khellactone (CKL) and the major active ingredient in Peucedani Radix which consists of the dried roots of Peucedanum praeruptorumDunn (Apiaceae). (±)-Praeruptorin A has been widely employed as one of the famous traditional Chinese medicines (TCMs) for the treatment of cough with thick sputum and dyspnea, nonproductive cough and upper respiratory infections for centuries in China. (±)-Praeruptorin A has dramatically therapeutic effects on hypertension mainly through acting as a Ca ²⁺-influx blocker .

HY-N7593

Tectoruside	Iris tectorum Maxim. Iridaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Lridaceae Plants Disease Research Fields Inflammation/Immunology	Others
Tectoruside is a phenol acid glycoside of the rhizome of Iris dichotoma Pall. Iris dichotoma Pall, a traditional Chinese herbal medicine, has been used in several disorders such as inflammation, throat disorders, asthma and coughs .

HY-N8624

Ethyl 3,4-dicaffeoylquinate	Structural Classification Source classification Phenols Polyphenols Plants Compositae Desmodium uncinatum DC.	Bacterial
Ethyl 3,4-dicaffeoylquinate is a phenolic acid isolated from G. divaricata. G. divaricata is one of the famous traditional Chinese herbs, usually used for bronchitis, tuberculosis, twisted knot cough, rheumatism, diabetes, etc .

HY-N0212

Peimine 1 Publications Verification Verticine; Dihydroisoimperialine	Alkaloids Piperidine Alkaloids Structural Classification Fritillaria thunbergii Miq. Liliaceae Classification of Application Fields Source classification Plants Inflammation/Immunology Disease Research Fields	Apoptosis Interleukin Related TNF Receptor p38 MAPK NF-κB
Peimine (Verticine; Dihydroisoimperialine) is an orally active natural product. Peimine has anti-inflammatory, analgesic and cough relieving effects. Peimine can be used in cancer and inflammation related research .

HY-N0789

Delsoline	Alkaloids Pyrrole Alkaloids Source classification Ranunculaceae Aconitum carmichaeli Debx. Plants	Others
Delsoline, a major alkaloid of Delphinium anthriscifolium Hance, has both a curare-like effect and a ganglion-blocking effect and is used to relieve muscle tension or hyperkinesia. D. anthriscifolium Hance has effects of dispelling wind and dampness, activating collaterals, and relieving pains and is used to treat rheumatism, hemiplegia, indigestion, and cough .

HY-19356

Rocaglamide Maximum Cited Publications 20 Publications Verification Roc-A; MG-002	Alkaloids Structural Classification Classification of Application Fields Other Alkaloids Source classification Plants Meliaceae Disease Research Fields Aglaia elliptifolia Cancer	NF-κB HSP Eukaryotic Initiation Factor (eIF)
Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC₅₀ of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia .

Cat. No.	Product Name	Chemical Structure

HY-B0264S

Guaifenesin-d3
Guaifenesin-d₃ is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough[1][2].

HY-B0372AS

Bromhexine-d3 hydrochloride

Bromhexine-d₃ (hydrochloride) is deuterium labeled Bromhexine (hydrochloride). Bromhexine hydrochloride is a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM. Bromhexine hydrochloride can prevent and manage SARS-CoV-2 infection. Bromhexine hydrochloride is an autophagy agonist. Bromhexine hydrochloride is a mucolytic cough suppressant and has the potential for a range of respiratory conditions[1][2][3][4].

HY-B0264S1

Guaifenesin-d5
Guaifenesin-d₅ is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough. Guaifenesin also has narcotic effect[1][2].

HY-A0161S

Chlophedianol-13C6
Chlophedianol- ¹³C₆ is the ¹³C labeled Chlophedianol (HY-A0161). Chlophedianol is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs)[1][2][3].

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MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
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Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks