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Results for "

DAPK

" in MedChemExpress (MCE) Product Catalog:

By Targets:	DAPK (7) Anaplastic lymphoma kinase (ALK) (1) Pim (1) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (5) Cardiovascular Disease (4) Inflammation/Immunology (1) Neurological Disease (1)

Inhibitors & Agonists

Screening Libraries

Peptides

Recombinant Proteins

Antibodies

Targets Recommended: DAPK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-153595

DAPK-IN-2

Others Cardiovascular Disease

DAPK-IN-2 is a DAPK inhibitor. DAPK-IN-2 can be used for the research of cerebral infarction and ischemic diseases .
HY-P1344A

DAPK Substrate Peptide TFA

DAPK Cancer

DAPK Substrate Peptide TFA is a synthetic peptide substrate for death associated protein kinase (DAPK), with a K_m of 9 μM .

DAPK-IN-2	Others	Cardiovascular Disease
DAPK-IN-2 is a *DAPK* inhibitor. DAPK-IN-2 can be used for the research of cerebral infarction and ischemic diseases .

DAPK Substrate Peptide TFA	DAPK	Cancer
DAPK Substrate Peptide TFA is a synthetic peptide substrate for death associated protein kinase (DAPK), with a K_m of 9 μM .

HY-RS03527

DAPK1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
DAPK1 Human Pre-designed siRNA Set A contains three designed siRNAs for DAPK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

DAPK1 Human Pre-designed siRNA Set A DAPK1 Human Pre-designed siRNA Set A

HY-RS03528

DAPK2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
DAPK2 Human Pre-designed siRNA Set A contains three designed siRNAs for DAPK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

DAPK2 Human Pre-designed siRNA Set A DAPK2 Human Pre-designed siRNA Set A

HY-RS03529

DAPK3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
DAPK3 Human Pre-designed siRNA Set A contains three designed siRNAs for DAPK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

DAPK3 Human Pre-designed siRNA Set A DAPK3 Human Pre-designed siRNA Set A

HY-15513

*TC-DAPK* 6** 5+ Cited Publications	DAPK	Cancer
TC-DAPK 6 is a potent, ATP-competitive, and highly selective *DAPK* inhibitor (IC₅₀=69 and 225 nM against *DAPK1* and *DAPK3*, respectively, with 10 μM ATP).

HY-15847

HS38 1 Publications Verification	DAPK	Cardiovascular Disease
HS38 is a potent, selective, and ATP-competitive inhibitor of death-associated protein kinase 1 (DAPK1) and zipper-interacting protein kinase (ZIPK, also called DAPK3), with K_ds of 300 nM and 280 nM, respectively. HS38 is also a PIM3 inhibitor with an IC₅₀ of 200 nM. HS38 can be used for the research of smooth muscle related disorders .

HY-149006

CK156	DAPK	Inflammation/Immunology Cancer
CK156 is a highly selective death-associated protein kinase (DAPK) inhibitor with IC₅₀s of 182 nM,34 μM, and 39 μM in the DRAK1 NanoBRET assay for DRAK1, CK2a1, and CK2a2, respectively. CK156 can be used for the research of autoimmune and inflammatory diseases .

HY-P5277

TAT-GluN2BCTM	DAPK	Neurological Disease
TAT-GluN2BCTM is a membrane-permeable *DAPK1*-targeting peptide. TAT-GluN2BCTM targets active DAPK1 to lysosomes for degradation. TAT-GluN2BCTM protects neurons from oxidative stress and NMDAR-mediated excitotoxicity by knocking down DAPK1. TAT-GluN2BCTM can be used in the study of neuroprotection .

HY-120040

HS94

DAPK Cardiovascular Disease

HS94 is a selective DAPK3 inhibitor. HS94 can be used for research of hypertension .

HS94	DAPK	Cardiovascular Disease
HS94 is a selective *DAPK3* inhibitor. HS94 can be used for research of hypertension .

HY-123983

HS56	Pim DAPK	Cardiovascular Disease
HS56 is an ATP-competitive dual *Pim/DAPK3* inhibitor with K_i values of 0.26, 0.208, 2.94, and ＞100 μM for DAPK3, Pim-3, Pim-1, and Pim-2, respectively. HS56 inhibits LC20 phosphorylation and smooth muscle contraction. HS56 decreases blood pressure in spontaneously hypertensive mice. HS56 can be used in research of hypertension .

HY-131909

CJ-2360	Anaplastic lymphoma kinase (ALK)	Cancer
CJ-2360 is a potent and orally active ALK inhibitor with IC₅₀s of 2.2, 4.0, 8.8, 6.3, and 8.9 nM against wild-type ALK and F1197M, G1269A, L1196M, and S1206Y ALK mutants, respectively. CJ-2360 displays potent inhibitory activity against two clinically reported ALK mutants (C1156Y and L1196M) and a few other kinases (LTK, MERTK, CLK1, DAPK1, and DAPK2) among the 468 kinases evaluated .

Cat. No.	Product Name

HY-L003

Apoptosis Compound Library	2218 compounds
Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and pathological conditions, which is also called programmed cell death (PCD). Apoptosis plays a crucial role in developing and maintaining the health of the body by eliminating old cells, unhealthy cells and unnecessary cells. Too little or too much apoptosis contribute to many diseases. When apoptosis does not work correctly, cells that should be eliminated may persist and become immortal, for example, in cancer and leukemia. When apoptosis works overly well, it kills too many cells and inflicts grave tissue damage. This is the case in strokes and neurodegenerative disorders such as Alzheimer's, Huntington's, and Parkinson's disease. MCE designs a unique collection of 2218 apoptosis-related compounds mainly focusing on the key targets in the apoptosis signaling pathway and can be used in the research of apoptosis signal pathway and related diseases.

Apoptosis Compound Library

2218 compounds

Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and pathological conditions, which is also called programmed cell death (PCD). Apoptosis plays a crucial role in developing and maintaining the health of the body by eliminating old cells, unhealthy cells and unnecessary cells. Too little or too much apoptosis contribute to many diseases. When apoptosis does not work correctly, cells that should be eliminated may persist and become immortal, for example, in cancer and leukemia. When apoptosis works overly well, it kills too many cells and inflicts grave tissue damage. This is the case in strokes and neurodegenerative disorders such as Alzheimer's, Huntington's, and Parkinson's disease.

MCE designs a unique collection of 2218 apoptosis-related compounds mainly focusing on the key targets in the apoptosis signaling pathway and can be used in the research of apoptosis signal pathway and related diseases.

Cat. No.	Product Name	Target	Research Area

HY-P1344A

DAPK Substrate Peptide TFA

DAPK Cancer

DAPK Substrate Peptide TFA is a synthetic peptide substrate for death associated protein kinase (DAPK), with a K_m of 9 μM .
HY-P1344

DAPK Substrate Peptide

Peptides Cancer

DAPK Substrate Peptide is a synthetic peptide substrate for death associated protein kinase (DAPK), with a K_m of 9 μM .

DAPK Substrate Peptide TFA	DAPK	Cancer
DAPK Substrate Peptide TFA is a synthetic peptide substrate for death associated protein kinase (DAPK), with a K_m of 9 μM .

DAPK Substrate Peptide	Peptides	Cancer
DAPK Substrate Peptide is a synthetic peptide substrate for death associated protein kinase (DAPK), with a K_m of 9 μM .

HY-P5277

TAT-GluN2BCTM	DAPK	Neurological Disease
TAT-GluN2BCTM is a membrane-permeable *DAPK1*-targeting peptide. TAT-GluN2BCTM targets active DAPK1 to lysosomes for degradation. TAT-GluN2BCTM protects neurons from oxidative stress and NMDAR-mediated excitotoxicity by knocking down DAPK1. TAT-GluN2BCTM can be used in the study of neuroprotection .

Species:	Human (4)
Tag:	His (2) GST (4)
Source:	Sf9 insect cells (4)

Cat. No.	Compare	Product Name	Species	Source

HY-P76858

	DAPK1 Protein, Human (sf9, His-GST) Death-associated protein kinase 1; DAP kinase 1; DAPK	Human	Sf9 insect cells
	The DAPK1 protein is a calcium/calmodulin-dependent kinase involved in multiple cellular pathways, regulating cell survival, apoptosis, and autophagy. The DAPK1 protein also acts as a signal amplifier for NMDA receptors, causing brain damage in stroke. DAPK1 Protein, Human (sf9, His-GST) is the recombinant human-derived DAPK1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of DAPK1 Protein, Human (sf9, His-GST) is 363 a.a., with molecular weight of ~64 kDa.

HY-P702658

DAPK2 Protein, Human (sf9, His, GST)

DAPK2; death associated protein kinase 2; DRP1; DRP-1
Human Sf9 insect cells
HY-P702657

DAPK1 Protein, Human (289a.a, sf9, GST)

Death-associated protein kinase 1; DAP kinase 1; DAPK
Human Sf9 insect cells

HY-P77286

	DAPK3/ZIPK Protein, Human (sf9, GST) Death-associated protein kinase 3; DAP kinase 3; Dlk; MYPT1 kinase; ZIPK	Human	Sf9 insect cells
	The DAPK3/ZIPK protein is a multifunctional serine/threonine kinase that complexly regulates apoptosis, autophagy, transcription, translation, and actin cytoskeletal reorganization. Its key roles include coordinating apoptotic and autophagy signaling, influencing smooth muscle contraction, and regulating starvation-induced autophagy. DAPK3/ZIPK Protein, Human (sf9, GST) is the recombinant human-derived DAPK3/ZIPK protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of DAPK3/ZIPK Protein, Human (sf9, GST) is 454 a.a., with molecular weight of ~70 kDa.


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Cat. No.	Product Name	Application	Reactivity

HY-P83053

DAP Kinase 1 Antibody (YA2798) DAK1; DAP K1; DAP kinase 1; DAPK 1; DAPK; DAPK1; DAPK1_HUMAN; Death Associated Protein Kinase 1; Death-associated protein kinase 1	WB, IHC-P, ICC/IF	Human, Mouse, Rat

HY-P82898

DAPK2 Antibody (YA2643)

DAPK2; Death-associated protein kinase 2; DAP kinase 2; DAP-kinase-related protein 1; DRP-1
WB, IHC-P Rat
HY-P82146

MIB1 Antibody (YA1891)

Dip1; LVNC7; MIB; mib1; ZZANK2; ZZZ6; DAPK-interacting protein 1; Mind bomb homolog 1; RING-type E3 ubiquitin transferase MIB1
WB, IHC-P, ICC/IF Human, Mouse
HY-P83574

DAP kinase 3 Antibody (YA3319)

DAPK3; ZIPK; Death-associated protein kinase 3; DAP kinase 3; DAP-like kinase; Dlk; MYPT1 kinase; Zipper-interacting protein kinase; ZIP-kinase
WB Human

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